Inhibitors | Comment | Organism | Structure |
---|---|---|---|
epicatechin | - |
Rattus norvegicus | |
kaempferol | - |
Rattus norvegicus | |
kaempferol 3-O-rutinoside | - |
Rattus norvegicus | |
additional information | flavonoids from Litsea japonica inhibit advanced glycation end products formation and rat lense aldose reductase in vitro with IC50 values of 0.0074-0.072 mM, flavonoid structure determinations by NMR spectroscopy, overview. No significant inhibition by 1, 2, afzelin, quercitrin, rutin, and lyoniside | Rattus norvegicus | |
Myricitrin | - |
Rattus norvegicus | |
quercetin 3-O-beta-D-apiofuranosyl-(1->2)-beta-D-glucopyranoside | - |
Rattus norvegicus | |
rhamnocitrin-3-O-rhamnoside | - |
Rattus norvegicus | |
tiliroside | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P07943 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lens | - |
Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
aldose reductase | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
additional information | - |
IC50 values and 95% confidence intervals of flavonoids from Litsea japonica on advanced glycation end products formation, IC50 values of 0.0074-0.072 mM, overview | Rattus norvegicus | additional information |
General Information | Comment | Organism |
---|---|---|
malfunction | inhibition of the enzyme causes advanced glycation end products formation | Rattus norvegicus |