Literature summary for 1.1.1.16 extracted from

Liu, J.J.; Zhang, G.C.; Kwak, S.; Oh, E.J.; Yun, E.J.; Chomvong, K.; Cate, J.H.D.; Jin, Y.S.
Overcoming the thermodynamic equilibrium of an isomerization reaction through oxidoreductive reactions for biotransformation (2019), Nat. Commun., 10, 1356 .

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Application

Application	Comment	Organism
synthesis	a yeast strain capable of consuming lactose intracellularly is engineered to produce tagatose from lactose. GAL1 coding for galactose kinase is deleted to eliminate galactose utilization. Heterologous xylose reductase (XR) and galactitol dehydrogenase (GDH) are introduced into the Gal1 deletion strain. The expression levels of XR and GDH are adjusted to maximize tagatose production. The resulting engineered yeast produces 37.69 g/l of tagatose from lactose with a tagatose and galactose ratio of 9:1 in the reaction broth	Rhizobium leguminosarum bv. viciae

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Saccharomyces cerevisiae	Rhizobium leguminosarum bv. viciae

Organism

Organism	UniProt	Comment	Textmining
Rhizobium leguminosarum bv. viciae	Q1MLL4	-	-

Synonyms

Synonyms	Comment	Organism
GDH	-	Rhizobium leguminosarum bv. viciae

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Release 2023.1 (January 2023)