Information on EC 5.4.99.54 - beta-seco-amyrin synthase

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The expected taxonomic range for this enzyme is: Arabidopsis thaliana

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EC NUMBER
COMMENTARY hide
5.4.99.54
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RECOMMENDED NAME
GeneOntology No.
beta-seco-amyrin synthase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(3S)-2,3-epoxy-2,3-dihydrosqualene = beta-seco-amyrin
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Sesquiterpenoid and triterpenoid biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, beta-seco-amyrin-forming)
The enzyme from Arabidopsis thaliana is multifunctional and produces about equal amounts of alpha- and beta-seco-amyrin. See EC 5.4.99.52, alpha-seco-amyrin synthase.
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(3S)-2,3-epoxy-2,3-dihydrosqualene
beta-seco-amyrin
show the reaction diagram
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beta-seco-amyrin is produced from the oleanyl cation through bond cleavage between C8 and C14
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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed in a lanosterol synthase-deficient Saccharomyces cerevisiae strain GIL77
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LINKS TO OTHER DATABASES (specific for EC-Number 5.4.99.54)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
InterPro (database of protein families, domains and functional sites)