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Information on EC 5.1.99.2 - 16-hydroxysteroid epimerase and Organism(s) Homo sapiens

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     5 Isomerases
         5.1 Racemases and epimerases
             5.1.99 Acting on other compounds
                5.1.99.2 16-hydroxysteroid epimerase
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Homo sapiens
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The taxonomic range for the selected organisms is: Homo sapiens
The enzyme appears in selected viruses and cellular organisms
Synonyms
16-Hydroxy steroid epimerase, Epimerase, 16-hydroxy steroid, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
16-Hydroxy steroid epimerase
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Epimerase, 16-hydroxy steroid
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
epimerization
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SYSTEMATIC NAME
IUBMB Comments
16-Hydroxysteroid 16-epimerase
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CAS REGISTRY NUMBER
COMMENTARY hide
37318-40-4
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
16alpha-Hydroxyestrone
16beta-Hydroxyestrone
show the reaction diagram
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3.9
16alpha-hydroxyestrone
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-
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6 - 8
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-
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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-
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
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-
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
-
exclusively in
Manually annotated by BRENDA team
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
45800 - 48500
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gel filtration
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
2°C, stable for at least 2 months
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Dahm, K.; Lindlau, M.; Breuer, H.
Steroidepimerase - ein neues Enzym des Íestrogenstoffwechsels
Biochim. Biophys. Acta
159
377-389
1968
Cavia porcellus, Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
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