We're sorry, but BRENDA doesn't work properly without JavaScript. Please make sure you have JavaScript enabled in your browser settings.
Information on EC 5.1.3.36 - heparosan-glucuronate 5-epimerase for references in articles please use BRENDA:EC5.1.3.36
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments The enzyme, characterized from the giant African snail Achatina fulica, participates in the biosynthetic pathway of acharan sulfate. Unlike EC 5.1.3.17, heparosan-N-sulfate-glucuronate 5-epimerase, it shows no activity with D-glucuronate residues in heparosan-N-sulfate.
The expected taxonomic range for this enzyme is: Achatina fulica
Synonyms
hg-5epi,
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
[heparosan]-D-glucuronate = [acharan]-L-iduronate
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
[heparosan]-D-glucuronate 5-epimerase
The enzyme, characterized from the giant African snail Achatina fulica, participates in the biosynthetic pathway of acharan sulfate. Unlike EC 5.1.3.17, heparosan-N-sulfate-glucuronate 5-epimerase, it shows no activity with D-glucuronate residues in heparosan-N-sulfate.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
[heparosan]-D-glucuronate
[heparosan]-L-iduronate
[heparosan]-D-glucuronate
[heparosan]-L-iduronate
A0A0C6EX43
it is suggested that the enzyme participates in the biosynthetic pathway of acharan sulfate
-
-
?
[heparosan]-D-glucuronate
[heparosan]-L-iduronate
A0A0C6EX43
no activity with [heparosan]-N-sulfate D-glucuronate. At equilibrium of the epimerization, the proportion of IdoA in the reaction product reaches up to 30% of total hexuronic acid
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
[heparosan]-D-glucuronate
[heparosan]-L-iduronate
A0A0C6EX43
it is suggested that the enzyme participates in the biosynthetic pathway of acharan sulfate
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CHAPS
A0A0C6EX43
0.1%, completely abolishes activity
sodium deoxycholate
A0A0C6EX43
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
5.5 - 7
A0A0C6EX43
pH 5.0: about 50% of maximal activity, pH 7.0: about 40% of maximal activity
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
A0A0C6EX43
UniProt
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
75000
A0A0C6EX43
x * 75000, SDS-PAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
?
A0A0C6EX43
x * 75000, SDS-PAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
35
A0A0C6EX43
unstable above
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
expressed in insect cells
A0A0C6EX43
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Mochizuki, H.; Yamagishi, K.; Suzuki, K.; Kim, Y.S.; Kimata, K.
Heparosan-glucuronate 5-epimerase: molecular cloning and characterization of a novel enzyme
Glycobiology
25
735-744
2015
Achatina fulica (A0A0C6EX43), Achatina fulica
brenda
Select items on the left to see more content.
html completed
HOME
login
history
all enzymes
BRENDA home
History
5.1.3.36 heparosan-glucuronate 5-epimerase
more
top
Information
