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Information on EC 4.2.1.74 - medium-chain-enoyl-CoA hydratase

for references in articles please use BRENDA:EC4.2.1.74

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IUBMB Comments

Acts in the reverse direction. The best substrate for the porcine enzyme is oct-2-enoyl-CoA. Unlike EC 4.2.1.17 enoyl-CoA hydratase, it does not act on crotonoyl-CoA.

The enzyme appears in viruses and cellular organisms

Synonyms
2-enoyl-coa hydratase 2, d-3-hydroxyacyl-coa dehydratase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a medium-chain (3S)-3-hydroxyacyl-CoA = a medium-chain trans-2-enoyl-CoA + H2O
show the reaction diagram
a medium-chain acyl-CoA = an acyl-CoA thioester where the acyl chain contains 6 to 12 carbon atoms.
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PATHWAY SOURCE
PATHWAYS
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Highest Expressing Human Cell Lines
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