Disease on EC 3.5.4.4 - adenosine deaminase

Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
5'-nucleotidase deficiency
Clinical consequences of enzyme deficiencies in the erythrocyte.
Ecto-5'-nucleotidase deficiency: association with adenosine deaminase deficiency and nonassociation with deoxyadenosine toxicity.
Inborn errors of purine metabolism: clinical update and therapies.
Abortion, Habitual
Interaction between adenosine deaminase and ABO system polymorphisms: effects on intrauterine survival and reproduction.
Abortion, Missed
Adenosine deaminase activity in serum and placenta of patients with anembryonic pregnancies and missed abortions.
Biochemical clinical factors associated with missed abortion independent of maternal age: A retrospective study of 795 cases with missed abortion and 694 cases with normal pregnancy.
Abortion, Spontaneous
Adenosine deaminase activity and its isoenzyme pattern in women with recurrent spontaneous abortions.
Adenosine deaminase and human reproduction: a comparative study of fertile women and women with recurrent spontaneous abortion.
Effect of ADA1 mother-fetus and wife-husband phenotypic differences on the ratio birth weight/placental weight in fertile women and on reproductive success in couples with RSA.
Repeated spontaneous abortion. Cooperative effects of ADA and ACP1 genetic polymorphisms.
The ADA*2 allele of the adenosine deaminase gene (20q13.11) and recurrent spontaneous abortions: an age-dependent association.
Abscess
Primary tuberculous abscess of the spleen in an immununocompetent patient diagnosed by biochemical markers and radiologic findings.
Acidosis, Lactic
Pearson bone marrow-pancreas syndrome with insulin-dependent diabetes, progressive renal tubulopathy, organic aciduria and elevated fetal haemoglobin caused by deletion and duplication of mitochondrial DNA.
Acne Vulgaris
Autoinflammatory diseases in childhood, part 1: monogenic syndromes.
The activity of adenosine deaminase and oxidative stress biomarkers in scraping samples of acne lesions.
Acquired Immunodeficiency Syndrome
Adenosine deaminase activity and acquired immunodeficiency syndrome (AIDS).
Adenosine deaminase in the acquired immunodeficiency syndrome.
Adenosine deaminase, acquired immunodeficiency syndrome (AIDS), and hepatitis B infection.
Elevated adenosine deaminase and purine nucleoside phosphorylase activity in peripheral blood null lymphocytes from patients with acquired immune deficiency syndrome.
Elevated erythrocyte adenosine deaminase activity in patients with acquired immunodeficiency syndrome.
In vitro modulation of purine enzyme metabolism and lymphocyte surface marker expression by thymosin fraction 5 in homosexual males.
Prognostic value of adenosine deaminase compared to other markers for progression to acquired immunodeficiency syndrome among intravenous drug users.
Retrovirally transduced CD34++ human cord blood cells generate T cells expressing high levels of the retroviral encoded green fluorescent protein marker in vitro.
[Adenosine deaminase in the cerebrospinal fluid of patients with acquired immunodeficiency syndrome]
Acute Coronary Syndrome
Impact of the rs73598374 polymorphism of the adenosine deaminase gene on platelet reactivity and long-term outcomes among patients with acute coronary syndrome treated with ticagrelor.
adenine phosphoribosyltransferase deficiency
Two-dimensional thin-layer chromatography for the screening of disorders of purine and pyrimidine metabolism.
Use of intact erythrocytes in the diagnosis of inherited purine and pyrimidine disorders.
Adenocarcinoma
Adenosine deaminase (ADA; E.C. no. 3.5.4.4.) in colorectal adenocarcinoma in man.
Adenosine deaminase activity in peripheral lymphocytes of patients with gynaecologic malignancies.
Adenosine modulates cell proliferation in human colonic adenocarcinoma. I. Possible involvement of adenosine A1 receptor subtypes in HT29 cells.
Increased Cytokeratin 19 Fragment Levels Are Positively Correlated with Adenosine Deaminase Activity in Malignant Pleural Effusions from Adenocarcinomas.
Quantitative changes in adenosine deaminase isoenzymes in human colorectal adenocarcinomas.
[Lactate dehydrogenase, adenosine deaminase and thymidine phosphorylase activity of blood and tissues in breast tumor patients]
Adenocarcinoma of Lung
Normal Tumor Markers and Increased Adenosine Deaminase in Pericardial Effusion Misdiagnosed as Tuberculous Pericarditis Ultimately Proven as Lung Adenocarcinoma with Pericardial Metastasis: a Case Report and Literature Review.
Adenofibroma
[Lactate dehydrogenase, adenosine deaminase and thymidine phosphorylase activity of blood and tissues in breast tumor patients]
adenosine deaminase deficiency
"Immune" Thrombocytopenia as Key Feature of a Novel ADA2 Deficiency Variant: Implication on Differential Diagnostics of ITP in Children.
1-Methyladenine in urine of an adenosine deaminase-deficient adult without immunodeficiency.
2-Chlorodeoxyadenosine (2-CdA): A Potent Chemotherapeutic and Immunosuppressive Nucleoside.
2-Chlorodeoxyadenosine in haematological malignancies.
2-Chlorodeoxyadenosine: hairy cell leukemia takes a surprising turn.
5'-Deoxy-5'-methylthioadenosine inhibition of rat T lymphocyte phosphodiesterase: correlation with inhibition of Con A induced proliferation.
A case of osteoporosis associated with adenosine deaminase deficiency.
A case of severe combined immunodeficiency caused by adenosine deaminase deficiency with a new mutation.
A clinical score to guide in decision making for monogenic type I IFNopathies.
A family of adenosine deaminase deficiency with severe combined immunodeficiency.
A girl with diabetes and severe combined immunodeficiency from adenosine deaminase deficiency.
A micromethod for determining adenosine deaminase and purine nucleoside phosphorylase activity in cells from human peripheral blood.
A new approach to detection of heterozygotes for adenosine deaminase deficiency: a hypothetical method.
A novel mutation in the ADA gene causing severe combined immunodeficiency in an Arab patient: a case report.
A phenotypically normal revertant of an adenosine deaminase-deficient lymphoblast cell line.
A Rare Case of Adenosine Deaminase 2 Deficiency Presenting With Temporal Arteritis.
A short perspective on gene therapy: Clinical experience on gene therapy of gliomablastoma multiforme.
A(2A) receptor dependent and A(2A) receptor independent effects of extracellular adenosine on murine thymocytes in conditions of adenosine deaminase deficiency.
Abnormal platelet aggregation in severe combined immunodeficiency disease with adenosine deaminase deficiency.
Abnormalities in S-adenosylhomocysteine hydrolysis, ATP catabolism, and lymphoid differentiation in adenosine deaminase deficiency.
Absence of oroticaciduria in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency.
Acquired hemoglobin H disease associated with idiopathic myelofibrosis and hereditary adenosine deaminase deficiency.
Activation of deoxycytidine kinase by deoxyadenosine: implications in deoxyadenosine-mediated cytotoxicity.
Adenosine and deoxyadenosine metabolism in the erythrocytes of a patient with adenosine deaminase deficiency.
Adenosine as a prostaglandin antagonist. Possible mechanism of the defect in combined immunodeficiency disease due to adenosine deaminase deficiency.
Adenosine deaminase 2 deficiency presenting as spastic paraplegia and systemic vasculitis.
Adenosine Deaminase 2 Deficiency: More Than Monogenic Vasculitis.
Adenosine deaminase activity and superoxide formation during phagocytosis and membrane perturbation of macrophages.
Adenosine deaminase activity in normal tissues and tissues from a child with severe combined immunodeficiency and adenosine deaminase deficiency.
Adenosine Deaminase Deficiency - More Than Just an Immunodeficiency.
Adenosine deaminase deficiency and chondro-osseous dysplasia.
Adenosine deaminase deficiency and immunodeficiencies.
Adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency in common variable immunodeficiency.
Adenosine deaminase deficiency and severe combined immunodeficiency disease.
Adenosine deaminase deficiency as the first target disorder in gene therapy.
Adenosine deaminase deficiency can present with features of Omenn syndrome.
Adenosine deaminase deficiency due to heterozygous abnormality consisting of a deletion of exon 7 and the absence of enzyme mRNA.
Adenosine deaminase deficiency in a child with severe combined immunodeficiency.
Adenosine deaminase deficiency in adults.
Adenosine deaminase deficiency in combined immunologic deficiency disease.
Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling.
Adenosine Deaminase Deficiency with a Novel Gene Mutation.
Adenosine deaminase deficiency with altered biochemical parameters in two sisters with late-onset immunodeficiency.
Adenosine deaminase deficiency with late onset of recurrent infections: response to treatment with polyethylene glycol-modified adenosine deaminase.
Adenosine deaminase deficiency with mosaicism for a "second-site suppressor" of a splicing mutation: decline in revertant T lymphocytes during enzyme replacement therapy.
Adenosine deaminase deficiency with normal immune function. An acidic enzyme mutation.
Adenosine deaminase deficiency without immunodeficiency: clinical and metabolic studies.
Adenosine deaminase deficiency.
Adenosine deaminase deficiency: a model system for human somatic cell gene correction therapy.
Adenosine deaminase deficiency: a review.
Adenosine deaminase deficiency: another family with "silent" ADA allele and normal ADA activity in two heterozygotes.
Adenosine deaminase deficiency: clinical expression, molecular basis, and therapy.
Adenosine deaminase deficiency: disappearance of adenine deoxynucleotides from a patient's erythrocytes after successful marrow transplantation.
Adenosine deaminase deficiency: frequency and comparative pathology in autosomally recessive severe combined immunodeficiency.
Adenosine deaminase deficiency: genotype-phenotype correlations based on expressed activity of 29 mutant alleles.
Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation.
Adenosine deaminase deficiency: molecular basis and recent developments.
Adenosine deaminase deficiency: the first inborn error of metabolism noted in immunodeficiency disease.
Adenosine deaminase deficiency: unanticipated benefits from the study of a rare immunodeficiency.
Adenosine deaminase impairment and ribonucleotide reductase activity and levels in HeLa cells.
Adenosine deaminase is not required for the generation of superoxide anion.
Adenosine deaminase messenger RNAs in lymphoblast cell lines derived from leukemic patients and patients with hereditary adenosine deaminase deficiency.
Adenosine inhibition of lymphocyte-mediated cytolysis: possible role of cyclic adenosine monophosphate.
Adenosine-induced apoptosis in EL-4 thymoma cells is caspase-independent and mediated through a non-classical adenosine receptor.
Adult onset immunodeficiency caused by inherited adenosine deaminase deficiency.
Adult presentation of adenosine deaminase deficiency.
Advances in basic and clinical immunology in 2011.
Advances of gene therapy for primary immunodeficiencies.
Altered regulation of S-adenosylmethionine dependent methylation in adenosine deaminase deficiency.
Alveolar-like Stem Cell-derived Myb(neg) Macrophages Promote Recovery and Survival in Airway Disease.
Amendment to Clinical Research Project. Project 90-C-195. April 1, 1993. Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with autologous lymphocytes transduced with a human ADA gene.
Amerioration of neurologic abnormalities after "enzyme replacement" in adenosine deaminase deficiency.
Aminohydrolases acting on adenine, adenosine and their derivatives.
An abnormal amino acid pattern in adenosine deaminase deficiency.
An improved screening test for adenosine deaminase deficiency.
Animal model for immune dysfunction associated with adenosine deaminase deficiency.
Antibody responses to bacteriophage phi X174 in patients with adenosine deaminase deficiency.
Are contemporary methods for somatic gene therapy suitable for clinical applications?
Atmospheric pressure ionization mass spectrometry of purine and pyrimidine markers of inherited metabolic disorders.
Atypical Omenn Syndrome due to Adenosine Deaminase Deficiency.
Autoimmune dysregulation and purine metabolism in adenosine deaminase deficiency.
Autoimmune thyroiditis and acquired hypothyroidism in an infant with severe combined immunodeficiency due to adenosine deaminase deficiency.
Autoinflammatory diseases in childhood, part 1: monogenic syndromes.
Basic defect in the expression of adenosine deaminase in ADA- SCID disease investigated through the cells of an obligate heterozygote.
Basis for the chondro-osseous dysplasia associated with adenosine deaminase deficiency: selective toxicity to immature chondrocytes.
Beware the lymphopenia: A case of severe combined immunodeficiency.
Bilateral sensorineural deafness in adenosine deaminase-deficient severe combined immunodeficiency.
Bone marrow gene therapy for adenosine deaminase deficiency.
Bone marrow gene transfer in three patients with adenosine deaminase deficiency.
Bone marrow transplantation and alternatives for adenosine deaminase deficiency.
Bone marrow transplantation in a case of severe combined immunodeficiency with adenosine deaminase deficiency [proceedings]
Brief report: hepatic dysfunction as a complication of adenosine deaminase deficiency.
Capillary electrophoresis in diagnosis and monitoring of adenosine deaminase deficiency.
Carrier erythrocyte entrapped adenosine deaminase therapy in adenosine deaminase deficiency.
Cellular gene therapy: an overview.
Cellular radiosensitivity in human severe-combined-immunodeficiency (SCID) syndromes.
Characterization of a cultured human T-cell line with genetically altered ribonucleotide reductase activity. Model for immunodeficiency.
Characterization of residual enzyme activity in fibroblasts from patients with adenosine deaminase deficiency and combined immunodeficiency: evidence for a mutant enzyme.
Characterization of the residual adenosine deaminating activity in the spleen of a patient with combined immunodeficiency disease and adenosine deaminase deficiency.
Chondroosseous dysplasia in severe combined immunodeficiency due to adenosine deaminase deficiency (chondroosseous dysplasia in ADA deficiency SCID).
Chronic leg ulcer revealing adenosine deaminase 2 deficiency: an atypical presentation.
Cicalese MP, Ferrua F, Castagnaro L, et al. Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency. Blood. 2016;128(1):45-54.
Clinical delineation of adenosine deaminase deficiency.
Combined Immunodeficiency Disease and Adenosine Deaminase Deficiency. A Molecular Defect.
Combined immunodeficiency disease associated with adenosine deaminase deficiency. Report on a workshop held in Albany, New York, October 1, 1973.
Comparative characterization of B-lymphoblastoid cell lines in adenosine deaminase deficiency and its heterozygote.
Comparison of red cell transfusion and polyethylene glycol-modified adenosine deaminase therapy in an adenosine deaminase-deficient child: measurement of erythrocyte deoxyadenosine triphosphate as a useful tool.
Complete and partial adenosine deaminase deficiency. Relationship of immune function to metabolite concentrations, enzyme activity, and effects of therapy.
Consensus approach for the management of severe combined immune deficiency caused by adenosine deaminase deficiency.
Consequences of adenosine deaminase deficiency on thymocyte metabolism.
Correct splicing despite mutation of the invariant first nucleotide of a 5' splice site: a possible basis for disparate clinical phenotypes in siblings with adenosine deaminase deficiency.
Correction of adenosine deaminase deficiency in cultured human T and B cells by retrovirus-mediated gene transfer.
Cost analysis of treatments for severe combined immunodeficiency patients caused by adenosine deaminase deficiency: comparison of gene therapy and bone marrow transplantation.
Current status and future prospects of human gene therapy.
dATP accumulation and ATP depletion in platelets in adenosine deaminase deficiency: significance for the immune response?
dATP causes specific release of cytochrome C from mitochondria.
Decreased S-adenosylhomocysteine hydrolase in inborn errors of purine metabolism.
Defective B cell tolerance in adenosine deaminase deficiency is corrected by gene therapy.
Delayed onset adenosine deaminase deficiency associated with acute disseminated encephalomyelitis.
Delayed-onset adenosine deaminase deficiency: Strategies for an early diagnosis.
Deoxyadenosine blockade of G0 to G1 transition in lymphocytes: possible involvement of protein kinases.
Deoxyadenosine inhibits DNA synthesis in cultured human fibroblasts.
Deoxyadenosine toxicity in an adenosine deaminase-inhibited human CCRF-CEM T-lymphoblastoid cell line causes cell swelling.
Deoxyadenosine triphosphate accumulation in erythrocytes of deoxycoformycin-treated mice.
Deoxyadenosine triphosphate as a potentially toxic metabolite in adenosine deaminase deficiency.
Deoxycoformycin-induced response in chronic lymphocytic leukaemia: deoxyadenosine toxicity in non-replicating lymphocytes.
Deoxycytidine excretion by mouse peritoneal macrophages: its implication in modulation of immunological functions.
Deoxycytidine therapy in two patients with adenosine deaminase deficiency and severe immunodeficiency disease.
Detection of JC virus by anti-VP1 immunohistochemistry in brains with progressive multifocal leukoencephalopathy.
Detection of the carrier state in combined immunodeficiency disease associated with adenosine deaminase deficiency.
Development of gene therapy for immunodeficiency: adenosine deaminase deficiency.
Development of gene therapy: potential in severe combined immunodeficiency due to adenosine deaminase deficiency.
Differential deoxyadenosine toxicity to immature rabbit cartilage in vitro. A model for the chondro-osseous dysplasia of adenosine deaminase deficiency.
Dipyridamole and intravenous deoxycytidine therapy in a patient with adenosine deaminase deficiency.
Disorders of purine and pyrimidine metabolism.
Disseminated infection with varicella-zoster virus vaccine strain presenting as hepatitis in a child with adenosine deaminase deficiency.
Drug evaluation: ADA-transduced hematopoietic stem cell therapy for ADA-SCID.
Dysregulation in B-cell responses and T follicular helper cell function in ADA2 deficiency patients.
Early prenatal investigation of a pregnancy at risk of adenosine deaminase deficiency using chorionic villi.
Ecto-5'-nucleotidase deficiency: association with adenosine deaminase deficiency and nonassociation with deoxyadenosine toxicity.
Ecto-enzyme activity of human erythrocyte adenosine deaminase.
Effect of adenosine deaminase replacement therapy on a child of adenosine deaminase deficiency with severe combined immunodeficiency disease.
Effect of red cell transfusions on clinical, immunological and biochemical parameters of a child with adenosine deaminase deficiency.
Effect of red cell transfusions, thymic hormone and deoxycytidine in severe combined immunodeficiency due to adenosine deaminase deficiency.
Effects of deoxyadenosine on ribonucleotide reductase in adenosine deaminase-deficient lymphocytes.
Effects of deoxyadenosine on the activation of ADA inhibited T & B cells.
Effects of deoxycoformycin in mice. III. A murine model reproducing multi-system pathology of human adenosine deaminase deficiency.
Elevation of serum IgE level and peripheral eosinophil count during T lymphocyte-directed gene therapy for ADA deficiency: implication of Tc2-like cells after gene transduction procedure.
Engraftment and chimerism, particularly of T- and B-cells, in children undergoing allogeneic bone marrow transplantation.
Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency.
Enzyme replacement and other biochemical approaches to the therapy of adenosine deaminase deficiency.
Enzyme replacement therapy for adenosine deaminase deficiency and severe combined immunodeficiency.
Enzyme replacement therapy of adenosine deaminase deficiency with polyethylene glycol-modified adenosine deaminase (PEG-ADA).
Enzyme replacement therapy with polyethylene glycol-adenosine deaminase in adenosine deaminase deficiency: overview and case reports of three patients, including two now receiving gene therapy.
Epstein-Barr virus-induced lymphoblastoid cell lines from patients with primary immunodeficiency diseases.
Errors of morphogenesis and inborn errors of immunity 20 years after the discovery of DiGeorge anomaly.
Erythrocyte adenosine deaminase deficiency without immunodeficiency. Evidence for an unstable mutant enzyme.
Evaluation of the expanded newborn screening program in New York City.
Evidence for distinct catabolic pathways of adenine ribonucleotides and deoxyribonucleotides in human T lymphoblastoid cells.
Evidence that X-linked severe combined immunodeficiency is not a differentiation defect of T lymphocytes.
Expression of a functional human adenosine deaminase in transgenic tobacco plants.
Extending the Clinical Phenotype of Adenosine Deaminase 2 Deficiency.
First trimester diagnosis of adenosine deaminase deficiency.
Food allergy in a patient with adenosine deaminase deficiency undergoing enzyme replacement with polyethylene glycol-modified adenosine deaminase.
Formation and degradation of deoxyadenosine nucleotides in inherited adenosine deaminase deficiency.
Gene Therapy Approaches to Immunodeficiency.
Gene therapy for adenosine deaminase deficiency.
Gene Therapy for Adenosine Deaminase Deficiency: A Comprehensive Evaluation of Short- and Medium-Term Safety.
Gene therapy for cystic fibrosis.
Gene therapy for immunodeficiency due to adenosine deaminase deficiency.
Gene therapy for inherited disorders.
Gene therapy for inherited immunodeficiencies.
Gene therapy for inherited immunodeficiency.
Gene therapy for monogenic disorders of the bone marrow.
Gene therapy for ovarian carcinoma.
Gene therapy for primary adaptive immune deficiencies.
Gene therapy for severe combined immune deficiency.
Gene therapy for severe combined immunodeficiency caused by adenosine deaminase deficiency: improved retroviral vectors for clinical trials.
Gene Therapy for Severe Combined Immunodeficiency due to Adenosine Deaminase Deficiency.
Gene Therapy for the Treatment of Primary Immune Deficiencies.
Gene therapy in cardiac arrhythmias.
Gene therapy in infants with severe combined immunodeficiency.
Gene therapy in man and mice: adenosine deaminase deficiency, ornithine transcarbamylase deficiency, and Duchenne muscular dystrophy.
Gene therapy in The Netherlands: highlights from the Low Countries.
Gene therapy of genetic diseases and cancer.
Gene therapy of primary T cell immunodeficiencies.
Gene therapy techniques.
Gene Therapy with Hematopoietic Stem Cells: The Diseased Bone Marrow's Point of View.
Gene therapy: here to stay.
Gene transfer and antisense nucleic acid techniques.
Gene transfer into hematopoietic stem cells as treatment for primary immunodeficiency diseases.
Generation of a high-titer packaging cell line for the production of retroviral vectors in suspension and serum-free media.
Genetic and biochemical consequences of adenosine deaminase deficiency in humans.
Genetic Engineering and Manufacturing of Hematopoietic Stem Cells.
Genetic expression in partial adenosine deaminase deficiency. mRNA levels and protein turnover for the enzyme variants in human B-lymphoblast cell lines.
Genetic heterogeneity in partial adenosine deaminase deficiency.
Genetic manipulation of hematopoietic stem cells in adenosine deaminase deficiency.
Genotoxicity of retroviral hematopoietic stem cell gene therapy.
Genotype is an important determinant of phenotype in adenosine deaminase deficiency.
Giant-cell fibroblastoma in a patient with a bone-marrow transplant.
Glaxo/MRS Young Investigator Medal. Molecular studies on adenosine deaminase deficiency and hereditary haemorrhagic telangiectasia.
Good Laboratory Practice Preclinical Safety Studies for GSK2696273 (MLV Vector-Based Ex Vivo Gene Therapy for Adenosine Deaminase Deficiency Severe Combined Immunodeficiency) in NSG Mice.
Hematopoietic stem cell gene therapy with drug resistance genes: an update.
Hematopoietic stem cell transplantation rescues the immunologic phenotype and prevents vasculopathy in patients with adenosine deaminase 2 deficiency.
Hereditary adenosine deaminase deficiency detected by screening test.
Hereditary sever combined immunodeficiency and adenosine deaminase deficiency.
Heterogeneity for adenosine deaminase deficiency: Expression of the enzyme in cultured skin fibroblasts and amniotic fluid cells.
Heterogeneity of biochemical, clinical and immunological parameters in severe combined immunodeficiency due to adenosine deaminase deficiency.
Heterogeneity of phenotype in two siblings with adenosine deaminase deficiency.
HLA typing of amniotic fluid cells for the prenatal determination of therapeutic transplantation options for a fetus affected with adenosine deaminase deficiency.
HLA-haploidentical bone marrow transplantation in three infants with adenosine deaminase deficiency: stable immunological reconstitution and reversal of skeletal abnormalities.
Homozygosity for a newly identified missense mutation in a patient with very severe combined immunodeficiency due to adenosine deaminase deficiency (ADA-SCID).
Host natural killer immunity is a key indicator of permissiveness for donor cell engraftment in patients with severe combined immunodeficiency.
Hot spot mutations in adenosine deaminase deficiency.
Human adenosine deaminase 2 deficiency: A multi-faceted inborn error of immunity.
Human gene therapy in gastrointestinal diseases: in vivo and in vitro approaches.
Human gene therapy: a brief overview of the genetic revolution.
Hyperbilirubinemia and Rapid Fatal Hepatic Failure in Severe Combined Immunodeficiency Caused by Adenosine Deaminase Deficiency (ADA-SCID).
Identification and quantitation of adenine deoxynucleotides in erythrocytes of a patient with adenosine deaminase deficiency and severe combined immunodeficiency.
Identification of a deletion in the adenosine deaminase gene in a child with severe combined immunodeficiency.
IgG antibody response to polyethylene glycol-modified adenosine deaminase in patients with adenosine deaminase deficiency.
IL-17 receptor A and adenosine deaminase 2 deficiency in siblings with recurrent infections and chronic inflammation.
Immunodeficiency disease in animals.
Immunodeficiency secondary to adenosine deaminase deficiency and purine nucleoside phosphorylation deficiency.
Immunological and metabolic reconstitution following successful bone marrow transplantation from a HLA-identical sibling in an infant with adenosine deaminase deficiency and severe combined immunodeficiency: partial restoration of purine metabolism.
Immunoreactive protein in adenosine deaminase deficient human lymphoblast cell lines.
Impaired germinal center maturation in adenosine deaminase deficiency.
Impulse oscillometry identifies peripheral airway dysfunction in children with adenosine deaminase deficiency.
In vitro and in vivo studies with human carrier erythrocytes loaded with polyethylene glycol-conjugated and native adenosine deaminase.
In vitro platelet abnormality in adenosine deaminase deficiency and severe combined immunodeficiency.
In vivo and in vitro effects of thymosin and adenosine deaminase on adenosine-deaminase-deficient lymphocytes.
In vivo inactivation of erythrocyte S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine in adenosine deaminase-deficient patients.
Inability of immunocompetent thymocytes to produce T-cell growth factor under adenosine deaminase deficiency conditions.
Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency.
Influence of adenosine deaminase inhibition on the phosphoinositide turnover in the initial stages of human T cell activation.
Inhibition of fetal thymic caspases abrogates the consequences of adenosine deaminase deficiency.
Inhibition of mitogen mediated lymphocyte blastogenesis by adenosine.
Inosine triphosphate pyrophosphohydrolase deficiency in a kindred with adenosine deaminase deficiency.
Insights into adenosine deaminase deficiency provided by murine fetal thymic organ culture with 2'-deoxycoformycin.
Insights into thymic purine metabolism and adenosine deaminase deficiency revealed by transgenic mice overexpressing ecto-5'-nucleotidase (CD73).
Insulin-dependent diabetes mellitus and severe atopic dermatitis in a child with adenosine deaminase deficiency.
Interleukin 2 liberation and absorption capacities of rat T lymphocytes in conditions of severe adenylic nucleotide pool depletion due to adenosine deaminase deficiency.
Interleukin 2 responsive lymphocytes in patients with adenosine deaminase deficiency.
Intravenous deoxycytidine therapy in a patient with adenosine deaminase deficiency.
Investor Outlook: Rising from the Ashes; GSK's European Approval of Strimvelis for ADA-SCID.
Iron overload as a result of transfusion therapy in a patient with adenosine deaminase deficiency.
Keratinocyte gene therapy for adenosine deaminase deficiency: a model approach for inherited metabolic disorders.
Lack of adenosine deaminase deficiency in the mutant mouse wasted.
Late-onset adenosine deaminase deficiency presenting with Heck's disease.
Limited effect of erythrocyte and plasma infusions in adenosine deaminase deficiency.
Liquid-chromatographic measurement of purine nucleotides in blood cells.
Lithium chloride induces partial responsiveness to LPS in nonresponder B cells.
Long-term culture and T cell receptor analysis of T cell clones isolated from a patient with adenosine deaminase deficiency and type I diabetes.
Long-term expression of human adenosine deaminase in rhesus monkeys transplanted with retrovirus-infected bone-marrow cells.
Lymphocyte dysfunction after DNA damage by toxic oxygen species. A model of immunodeficiency.
Lymphocyte subpopulations in primary immunodeficiency disorders.
Lymphocytes as cellular vehicles for gene therapy in mouse and man.
Lymphokine-activated killer cells in primary immunodeficiencies and acquired immunodeficiency syndrome.
Lymphoma in a patient with severe combined immunodeficiency with adenosine deaminase deficiency, following unsustained engraftment of histoincompatible T cell-depleted bone marrow.
Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: possible role of nucleoside kinase(s).
Management of Gaucher disease in a post-communist transitional health care system: Croatian experience.
Management options for adenosine deaminase deficiency; proceedings of the EBMT satellite workshop (Hamburg, March 2006).
Management options: SCIDS with adenosine deaminase deficiency.
Memory of extracellular adenosine A2A purinergic receptor-mediated signaling in murine T cells.
Metabolic abnormalities of human adenosine deaminase deficiency reproduced in the mouse by 2'-deoxycoformycin, and adenosine deaminase inhibitor.
Metabolic basis for immune dysfunction in adenosine deaminase deficiency.
Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction.
Metabolic findings in a patient with adenosine deaminase deficiency and severe combined immunodeficiency.
Molecular analysis of T lymphocyte-directed gene therapy for adenosine deaminase deficiency: long-term expression in vivo of genes introduced with a retroviral vector.
Molecular basis of adenosine deaminase deficiency.
Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution.
Morphological changes in leukemic lymphoblasts and normal lymphocytes treated with deoxyadenosine plus deoxycoformycin.
Neurologic abnormalities in patients with adenosine deaminase deficiency.
Neutropenia among patients with adenosine deaminase deficiency.
Neutropenia and myeloid dysplasia in a patient with delayed-onset adenosine deaminase deficiency.
New insights into adenosine-receptor-mediated immunosuppression and the role of adenosine in causing the immunodeficiency associated with adenosine deaminase deficiency.
New models for the study of adenosine deaminase deficiency.
Newborn screening for severe combined immunodeficiency: an opportunity for intervention.
Non-infectious Lung Disease in Patients with Adenosine Deaminase Deficient Severe Combined Immunodeficiency.
Nonmyeloablative stem cell transplantation for congenital immunodeficiencies.
Nucleoside kinases in T and B lymphoblasts distinguished by autoradiography.
Nucleotide pool imbalance and adenosine deaminase deficiency induce alterations of N-region insertions during V(D)J recombination.
Outcomes of patients with severe combined immunodeficiency treated with hematopoietic stem cell transplantation with and without preconditioning.
Overproduction of adenine deoxynucleosides and deoxynucletides in adenosine deaminase deficiency with severe combined immunodeficiency disease.
Overview of biochemical abnormalities and molecular genetics of adenosine deaminase deficiency.
p53 expression is required for thymocyte apoptosis induced by adenosine deaminase deficiency.
Paradoxical expression of adenosine deaminase in T cells cultured from a patient with adenosine deaminase deficiency and combine immunodeficiency.
Partial adenosine deaminase deficiency: another family from southern Africa.
Partial resolution of bone lesions. A child with severe combined immunodeficiency disease and adenosine deaminase deficiency after enzyme-replacement therapy.
Patients with adenosine deaminase deficiency surviving after hematopoietic stem cell transplantation are at high risk of CNS complications.
Pattern recognitions receptors in immunodeficiency disorders.
PEG-ADA replacement therapy for adenosine deaminase deficiency: an update after 8.5 years.
PEG-ADA: an alternative to haploidentical bone marrow transplantation and an adjunct to gene therapy for adenosine deaminase deficiency.
Pegademase bovine (PEG-ADA) for the treatment of infants and children with severe combined immunodeficiency (SCID).
Perspectives of gene therapy for primary immunodeficiencies.
Polyethylene glycol-conjugated adenosine phosphorylase: development of alternative enzyme therapy for adenosine deaminase deficiency.
Polyethylene glycol-modified adenosine deaminase improved lung disease but not liver disease in partial adenosine deaminase deficiency.
Polymorphism of S-adenosylhomocysteine hydrolase in Italy.
Positive correlation between adenosine deaminase activity and superoxide formation during phagocytosis.
Potential of gene therapy in bone marrow transplantation.
Preclinical demonstration of lentiviral vector-mediated correction of immunological and metabolic abnormalities in models of adenosine deaminase deficiency.
Prenatal detection of a probable heterozygote for ADA deficiency and severe combined immunodeficiency disease using a microradioassay.
Prenatal diagnosis for adenosine deaminase deficiency.
Prenatal diagnosis of three cases of severe combined immunodeficiency: severe T cell deficiency during the first half of gestation in fetuses with adenosine deaminase deficiency.
Primary hyperoxaluria and adenosine deaminase deficiency without immunodeficiency.
Probable autoimmune thyroid disease and combined immunodeficiency disease.
Production of IL-4 and expression of CD40 ligand by human CD8 T cells.
Progress and prospects: gene therapy for inherited immunodeficiencies.
Progress in genetic therapy for severe combined immunodeficiency associated with adenosine deaminase deficiency.
Protection by various deoxynucleosides against deoxyadenosine-induced DNA damage in adenosine deaminase-inactivated lymphocytes.
Pulmonary alveolar proteinosis in patients with adenosine deaminase deficiency.
Purine deoxynucleoside toxicity in nondividing human lymphoid cells.
Purine dysfunction in cells from patients with adenosine deaminase deficiency.
Purine excretion by cultured skin fibroblasts from patients with abnormal purine metabolism.
Purine excretion by mouse peritoneal macrophages lacking adenosine deaminase activity.
Purine metabolic enzymes in lymphocytes. IV. Effects of enzyme inhibitors and enzyme substrates on the blastogenic responses of human lymphocytes.
Purine metabolism in adenosine deaminase deficiency.
Purine metabolism of lymphocytes. Targets for chemotherapy drug development.
Purine metabolism, immune reconstitution, and abdominal adipose tumor after gene therapy for adenosine deaminase deficiency.
Purine nucleoside metabolism in the erythrocytes of patients with adenosine deaminase deficiency and severe combined immunodeficiency.
Purine nucleoside modulation of functions of human lymphocytes.
Rapid prenatal diagnosis of adenosine deaminase deficiency and other purine disorders using foetal blood.
Recalcitrant palmoplantar warts associated with adult-onset adenosine deaminase deficiency.
Recent developments and new frontiers in childhood arterial ischemic stroke.
Recombinant proteins for genetic disease.
Reconstitution of T- and B-cell function after T-lymphocyte-depleted haploidentical bone marrow transplantation in severe combined immunodeficiency due to adenosine deaminase deficiency.
Red-blood-cell adenosine deaminase deficiency in a "healthy" Kung individual.
Regulation of deoxyadenosine and nucleoside analog phosphorylation by human placental adenosine kinase.
Rejection of bone marrow transplant and resistance of alloantigen reactive cells to in vivo deoxyadenosine in adenosine deaminase deficiency.
Retrospective TREC testing of newborns with Severe Combined Immunodeficiency and other primary immunodeficiency diseases.
Role of adenosine deaminase in the early stages of precursor T cell maturation.
Role of reduced intensity conditioning in T-cell and B-cell immune reconstitution after HLA-identical bone marrow transplantation in ADA-SCID.
S-Adenosylhomocysteine accumulation and selective cytotoxicity in cultured T- and B-lymphocytes.
S-Adenosylhomocysteine hydrolase activity in a lymphoblastoid cell line from a patient with adenosine deaminase dificiency disease.
SCID: the role of adenosine deaminase deficiency.
Screening for primary immunodeficiencies associated with purine nucleoside phosphorylase deficiency or adenosine deaminase deficiency.
Sensorineural deafness in siblings with adenosine deaminase deficiency.
Severe combined immunodeficiency and adenosine deaminase deficiency.
Severe combined immunodeficiency and adenosine deaminase deficiency: failure of enzyme replacement therapy.
Severe combined immunodeficiency disease with adenosine deaminase deficiency.
Severe combined immunodeficiency disease, adenosine deaminase deficiency and gene therapy.
Severe combined immunodeficiency due to adenosine deaminase deficiency.
Severe combined immunodeficiency: a national surveillance study.
Severe combined immunodeficiency: a retrospective single-center study of clinical presentation and outcome in 117 patients.
Severe Combined Immunodeficiency: A Review for Neonatal Clinicians.
Severe phenotype of severe combined immunodeficiency caused by adenosine deaminase deficiency in a patient with a homozygous mutation due to uniparental disomy.
Short stature/short limb skeletal dysplasia with severe combined immunodeficiency and bowing of the femora: report of two patients and review.
Somatic cell gene therapy: the model of adenosine deaminase deficiency.
Spontaneous in vivo reversion to normal of an inherited mutation in a patient with adenosine deaminase deficiency.
Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity.
Steps toward gene therapy: 1. The initial trials.
Strategies for Retrovirus-Based Correction of Severe, Combined Immunodeficiency (SCID).
Strimvelis® for Treating Severe Combined Immunodeficiency Caused by Adenosine Deaminase Deficiency: An Evidence Review Group Perspective of a NICE Highly Specialised Technology Evaluation.
Stroke as Initial Manifestation of Adenosine Deaminase 2 Deficiency.
Studies of the relationship between adenosine deaminase and immune function.
Substrate inhibition of adenosine phosphorylation in adenosine deaminase deficiency and adenosine-mediated inhibition of PP-ribose-P dependent nucleotide synthesis in hypoxanthine phosphoribosyltransferase deficient erythrocytes.
Successful bone marrow transplantation and treatment of BCG infection in two patients with severe combined immunodeficiency.
Successful bone marrow transplantation with reduced intensity conditioning in a patient with delayed-onset adenosine deaminase deficiency.
Successful peripheral T-lymphocyte-directed gene transfer for a patient with severe combined immune deficiency caused by adenosine deaminase deficiency.
Tandem mass spectrometry, but not T-cell receptor excision circle analysis, identifies newborns with late-onset adenosine deaminase deficiency.
Testing newborns for adenosine deaminase deficiency not cost effective.
The chondro-osseous dysplasia of adenosine deaminase deficiency with severe combined immunodeficiency.
The different extent of B and T cell immune reconstitution after hematopoietic stem cell transplantation and enzyme replacement therapies in SCID patients with adenosine deaminase deficiency.
The effects of an induced adenosine deaminase deficiency on T-cell differentiation in the rat.
The human genes for S-adenosylhomocysteine hydrolase and adenosine deaminase are syntenic on chromosome 20.
The Many Faces of a Monogenic Autoinflammatory Disease: Adenosine Deaminase 2 Deficiency.
The mechanism of inhibition and "reversal" of mitogen-induced lymphocyte activation in a model of adenosine deaminase deficiency.
The molecular genetics of pediatric lipid disorders: recent progress and future research directions.
The role of de novo purine synthesis in lymphocyte transformation.
The same mutation in a family with adenosine deaminase 2 deficiency.
The treatment of adenosine deaminase deficiency.
The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice. Differential impact on pulmonary and immunologic abnormalities.
Thirty Years of Followup in 3 Patients with Familial Polyarteritis Nodosa due to Adenosine Deaminase 2 Deficiency.
Toll-like receptor signaling in primary immune deficiencies.
Towards a rAAV-based gene therapy for ADA-SCID: from ADA deficiency to current and future treatment strategies.
Towards gene therapy for adenosine deaminase deficiency.
Towards gene therapy for the central nervous system.
Treatment of adenosine deaminase deficiency with polyethylene glycol-modified adenosine deaminase.
Treatment of adenosine deaminase deficiency.
Treatment of respiratory viral infection in an immunodeficient infant with ribavirin aerosol.
Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with CD34+ selected autologous peripheral blood cells transduced with a human ADA gene. Amendment to clinical research project, Project 90-C-195, January 10, 1992.
Two-dimensional thin-layer chromatography for the screening of disorders of purine and pyrimidine metabolism.
Ultra-performance liquid chromatography-tandem mass spectrometry-based multiplex enzyme assay for six enzymes associated with hereditary hemolytic anemia.
Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency.
Urinary excretion of purines, purine nucleosides, and pseudouridine in adenosine deaminase deficiency.
Urogenital Abnormalities in Adenosine Deaminase Deficiency.
Variable Clinical Phenotypes and Relation of Interferon Signature with Disease Activity in ADA2 Deficiency.
Workshop on severe combined immunological deficiency disease and adenosine deaminase deficiency. Albany, New York, on October 1, 1973.
[A method detecting heterozygotes for adenosine deaminase deficiency with blood samples dried on filter paper]
[Adenosine deaminase deficiency and severe combined immunodeficiency]
[Adenosine deaminase deficiency associated severe combined immunodeficiency with disseminated varicella infection after vaccination: a case report]
[Adenosine deaminase deficiency in primary immunodeficiencies (author's transl)]
[Adenosine deaminase deficiency]
[Adenosine deaminase 1 deficiency, an inborn error of metabolism underlying a severe form of combined immunodeficiency].
[Clinical study of gene therapy for adenosine deaminase deficiency]
[Current status and future prospects of stem cell gene therapy for primary immunodeficiency].
[Diagnosis and treatment of Gaucher disease in Croatia]
[Gene therapy for adenosine deaminase deficiency]
[Gene therapy for severe combined immunodeficiency]
[Gene therapy: a review 6 years after the first trials in man. Round Table No 6 at Giens XIII]
[Gene therapy: application possibilities]
[Gene transfer and gene therapy]
[Immunological failure caused by adenosine deaminase deficiency]
[Molecular pathology of immunological deficiency. Apropos of adenosine deaminase deficiency and nucleoside phosphorylase deficiency]
[Polyethylene glycol-adenosine deaminase: a new adenosine deaminase deficiency therapy. Value of deoxyadenosine triphosphate determination for therapeutic monitoring]
[Present status and future prospects of human gene therapy]
[Principles, possibilities and limits of gene therapy]
[Severe combined immunodeficiency with adenosine deaminase deficiency (author's transl)]
[Severe combined immunodeficiency: description of a clinical case]
[Transplantation of T cell-depleted marrow from parents in a case of severe combined immunodeficiency with adenosine deaminase deficiency]
[Treatment of adenosine deaminase deficiency using gene transfer]
[Treatment of adenosine deaminase deficiency with adenosine deaminase combined with polyethylene glycol]
[Treatment of primary immune defects]
[Treatment of severe combined immunodeficiency with bone marrow or foetal liver transplants (author's transl)]
adenosine kinase deficiency
Increased expression of one of two adenosine deaminase alleles in a human choriocarcinoma cell line following selection with adenine nucleosides.
adenylate kinase deficiency
Hereditary disorders of erythrocyte enzymes in non-glycolytic metabolic pathways.
Adrenoleukodystrophy
Genotoxicity of retroviral hematopoietic stem cell gene therapy.
Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity.
Agammaglobulinemia
A case of hypogammaglobulinemia with enteroviral meningoencephalitis, associated with increased adenosine deaminase in cerebrospinal fluid.
Dysregulation in B-cell responses and T follicular helper cell function in ADA2 deficiency patients.
Observational, hypothesis-driven and genomics research strategies for analyzing inherited differences in responses to infectious diseases.
AIDS-Related Complex
Enhancement of erythrocytic adenosine deaminase following treatment of AIDS-related complex/AIDS patients with zidovudine.
Airway Obstruction
Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction.
Alopecia Areata
Oxidative Stress Biomarkers and Adenosine Deaminase over the Alopecic Area of the Patients with Alopecia Areata.
alpha-Thalassemia
Acquired hemoglobin H disease associated with idiopathic myelofibrosis and hereditary adenosine deaminase deficiency.
Alzheimer Disease
Purine-related metabolites and their converting enzymes are altered in frontal, parietal and temporal cortex at early stages of Alzheimer's disease pathology.
amidase deficiency
Adenosine as a prostaglandin antagonist. Possible mechanism of the defect in combined immunodeficiency disease due to adenosine deaminase deficiency.
Amendment to Clinical Research Project. Project 90-C-195. April 1, 1993. Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with autologous lymphocytes transduced with a human ADA gene.
Cicalese MP, Ferrua F, Castagnaro L, et al. Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency. Blood. 2016;128(1):45-54.
Differential deoxyadenosine toxicity to immature rabbit cartilage in vitro. A model for the chondro-osseous dysplasia of adenosine deaminase deficiency.
Effects of deoxycoformycin in mice. III. A murine model reproducing multi-system pathology of human adenosine deaminase deficiency.
Glaxo/MRS Young Investigator Medal. Molecular studies on adenosine deaminase deficiency and hereditary haemorrhagic telangiectasia.
Partial resolution of bone lesions. A child with severe combined immunodeficiency disease and adenosine deaminase deficiency after enzyme-replacement therapy.
[Molecular pathology of immunological deficiency. Apropos of adenosine deaminase deficiency and nucleoside phosphorylase deficiency]
Amyloidosis
Renal Amyloidosis in Deficiency of Adenosine Deaminase 2: Successful Experience With Canakinumab.
Amyotrophic Lateral Sclerosis
Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis.
Autophagy in spinal motor neurons of conditional ADAR2-knockout mice: An implication for a role of calcium in increased autophagy flux in ALS.
Cell death cascade and molecular therapy in ADAR2-deficient motor neurons of ALS.
Co-Occurrence of TDP-43 Mislocalization with Reduced Activity of an RNA Editing Enzyme, ADAR2, in Aged Mouse Motor Neurons.
The molecular link between inefficient GluA2 Q/R site-RNA editing and TDP-43 pathology in motor neurons of sporadic amyotrophic lateral sclerosis patients.
Unique nuclear vacuoles in the motor neurons of conditional ADAR2-knockout mice.
[Perampanel for Sporadic Amyotrophic Lateral Sclerosis].
Anaphylaxis
Effect of adenosine on histamine release and atrioventricular conduction during guinea pig cardiac anaphylaxis.
Anemia
Erythrocyte adenosine deaminase levels are elevated in Diamond Blackfan anemia but not in the 5q- syndrome.
Erythrocyte disorders of purine and pyrimidine metabolism.
Evaluation of the expanded newborn screening program in New York City.
High adenosine deaminase level among healthy probands of Diamond Blackfan anemia (DBA) cosegregates with the DBA gene region on chromosome 19q13. The DBA Working Group of Société d'Immunologie Pédiatrique (SHIP).
Increased adenosine deaminase activity in a patient with cartilage-hair hypoplasia.
Role of adenosine signaling in coordinating cardiomyocyte function and coronary vascular growth in chronic fetal anemia.
[Diamond-Blackfan anemia confirmed by RPS19 gene mutation analysis: a case study and literature review of Korean patients]
[Influence of iron deficiency anemia on development of thymus and spleen and adenosine deaminase activity in rats]
Anemia, Aplastic
Pearson bone marrow-pancreas syndrome with insulin-dependent diabetes, progressive renal tubulopathy, organic aciduria and elevated fetal haemoglobin caused by deletion and duplication of mitochondrial DNA.
Anemia, Diamond-Blackfan
Comparative activity of erythrocyte adenosine deaminase and orotidine decarboxylase in Diamond-Blackfan anemia.
Elevated red cell adenosine deaminase activity: a marker of disordered erythropoiesis in Diamond-Blackfan anaemia and other haematologic diseases.
Erythrocyte adenosine deaminase levels are elevated in Diamond Blackfan anemia but not in the 5q- syndrome.
Erythrocyte adenosine deaminase: diagnostic value for Diamond-Blackfan anaemia.
High adenosine deaminase level among healthy probands of Diamond Blackfan anemia (DBA) cosegregates with the DBA gene region on chromosome 19q13. The DBA Working Group of Société d'Immunologie Pédiatrique (SHIP).
Nomimmune hydrops fetalis due to Diamond-Blackfan anemia.
Transient erythrophagocytosis in Diamond-Blackfan anemia.
Anemia, Hemolytic
Adenosine deaminase (ADA) overproduction associated with congenital hemolytic anemia: case report and molecular analysis.
ATP depletion as a consequence of adenosine deaminase inhibition in man.
Autosomal dominant hemolytic anemia and adenosine deaminase overproduction.
Biochemical study of a case of hemolytic anemia with increased (85 fold) red cell adenosine deaminase.
Biochemical study of a case of hemolytic anemia with increased (85-fold) red cell adenosine deaminase.
Erythrocyte adenosine deaminase overproduction in hereditary hemolytic anemia.
Erythrocyte disorders of purine and pyrimidine metabolism.
Erythrocyte-specific overproduction of adenosine deaminase: molecular genetic studies.
Hereditary disorders of erythrocyte enzymes in non-glycolytic metabolic pathways.
Hereditary overexpression of adenosine deaminase in erythrocytes: evidence for a cis-acting mutation.
Hereditary overexpression of adenosine deaminase in erythrocytes: studies in erythroid cell lines and transgenic mice.
Increased erythrocyte adenosine deaminase activity without haemolytic anaemia.
Molecular basis of erythroenzymopathies associated with hereditary hemolytic anemia: tabulation of mutant enzymes.
Overproduction of structurally normal enzyme in man: hereditary haemolytic anaemia with increased red cell adenosine deaminase activity.
Recent progress in the molecular genetic analysis of erythroenzymopathy.
Red cell enzymopathies as a model of inborn errors of metabolism.
Studies on pyruvate kinase deficiency, pyrimidine 5-'nucleotidase deficiency and adenosine deaminase overproduction.
Three kinds of foamy cells in the spleen: comparative histochemical and ultrastructural studies.
[Pathophysiology and laboratory tests of hemolytic anemia: with special reference to erythroenzymopathies]
Anemia, Hemolytic, Autoimmune
Heterozygous Mutation in Adenosine Deaminase Gene in a Patient With Severe Lymphopenia Following Corticosteroid Treatment of Autoimmune Hemolytic Anemia.
Anemia, Hemolytic, Congenital
A case of red-cell adenosine deaminase overproduction associated with hereditary hemolytic anemia found in Japan.
Adenosine deaminase (ADA) overproduction associated with congenital hemolytic anemia: case report and molecular analysis.
Elevated adenosine deaminase activity and hereditary hemolytic anemia. Evidence for abnormal translational control of protein synthesis.
Elevated erythrocyte adenosine deaminase activity in congenital hypoplastic anemia.
Erythrocyte adenosine deaminase overproduction in hereditary hemolytic anemia.
Hereditary hemolytic anemia with increased red cell adenosine deaminase (45- to 70-fold) and decreased adenosine triphosphate.
Purification and properties of adenosine deaminase in normal and hereditary hemolytic anemia with increased red cell activity.
Anemia, Hypoplastic, Congenital
Complexities of genetic diagnosis illustrated by an atypical case of congenital hypoplastic anemia.
Elevated erythrocyte adenosine deaminase activity in congenital hypoplastic anemia.
Anemia, Iron-Deficiency
[Influence of iron deficiency anemia on development of thymus and spleen and adenosine deaminase activity in rats]
Anemia, Pernicious
Adenosine deaminase activity in gastric mucosa of pernicious anemia patients. Effect of treatment with cyanocobalamin (vitamin B12).
Anemia, Sickle Cell
Evaluation of the expanded newborn screening program in New York City.
Anemia, Sideroblastic
Elevated erythrocyte adenosine deaminase activity in a patient with primary acquired sideroblastic anemia.
Angina, Stable
Adenosine deaminase activity in blood of patients with stable angina pectoris.
Angina, Unstable
5'-nucleotidase and adenosine deaminase activities in blood of patients with unstable angina pectoris.
Anthrax
Serum adenosine deaminase activity in cutaneous anthrax.
Antiphospholipid Syndrome
Novel CECR1 gene mutations causing deficiency of adenosine deaminase 2, mimicking antiphospholipid syndrome.
Appendicitis
Serum adenosine deaminase levels in diagnosis of acute appendicitis.
Arrhythmias, Cardiac
Adenosine deaminase and BW A1433U attenuate hypoxia-induced ventricular ectopy.
Gene therapy in cardiac arrhythmias.
Arteriosclerosis
[Peripheral blood albumin level in significantly correlated with the severity of atherosclerosis in hypertensive patients].
Arthritis
A clinical score to guide in decision making for monogenic type I IFNopathies.
A fatal case of tuberculous meningitis in a child with juvenile idiopathic arthritis: a diagnostic challenge.
Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis.
Autoinflammatory diseases in childhood, part 1: monogenic syndromes.
Modulatory effect of eugenol on arginase, nucleotidase, and adenosine deaminase activities of platelets in a carrageenan-induced arthritis rat model: A possible anti-arthritic mechanism of eugenol.
Sensitivity and specificity of adenosine deaminase in diagnosis of juvenile idiopathic arthritis.
Synovial fluid adenosine deaminase activity to diagnose tuberculous septic arthritis.
[Activity of adenosine deaminase in the serum of children ill with rheumatism and chronic progressive arthritis]
[Adenosine deaminase activity in tuberculous arthritis and other monoarthritis]
[Adenosine deaminase in tuberculous arthritis]
Arthritis, Experimental
Effects of pentostatin (2'deoxycoformycin), an inhibitor of adenosine deaminase, on type II collagen-induced arthritis in rats.
Methotrexate and erythro-9-(2-hydroxynon-3-yl) adenine therapy for rat adjuvant arthritis and the effect of methotrexate on in vivo purine metabolism.
Arthritis, Gouty
[Adenosine deaminase activity in the lymphocytes of patients with gouty arthritis]
Arthritis, Infectious
Synovial fluid adenosine deaminase activity to diagnose tuberculous septic arthritis.
Arthritis, Juvenile
A clinical score to guide in decision making for monogenic type I IFNopathies.
A fatal case of tuberculous meningitis in a child with juvenile idiopathic arthritis: a diagnostic challenge.
Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis.
Adenosine deaminase activity and its isoenzyme pattern in patients with juvenile rheumatoid arthritis and systemic lupus erythematosus.
Management of Gaucher disease in a post-communist transitional health care system: Croatian experience.
Sensitivity and specificity of adenosine deaminase in diagnosis of juvenile idiopathic arthritis.
[Diagnosis and treatment of Gaucher disease in Croatia]
Arthritis, Reactive
Serum and synovial fluid adenosine deaminase activity in patients with rheumatoid arthritis, osteoarthritis, and reactive arthritis.
Arthritis, Rheumatoid
A study of adenosine-deaminase genetic polymorphism in rheumatoid arthritis.
Activities of enzymes that hydrolyze adenine nucleotides in lymphocytes from patients with rheumatoid arthritis.
Adenosine Deaminase activity and HLA-DRB as diagnostic markers for Rheumatoid Arthritis.
Adenosine deaminase and C-reactive protein in diagnosing and monitoring of rheumatoid arthritis.
Adenosine deaminase in the modulation of immune system and its potential as a novel target for treatment of inflammatory disorders.
Assessment of adenosine deaminase levels in rheumatoid arthritis patients receiving anti-TNF-alpha therapy.
Biochemical analysis of pleural fluid: what should we measure?
Comparison of adenosine deaminase levels in serum and synovial fluid between patients with rheumatoid arthritis and osteoarthritis.
Correlation of serum levels of adenosine deaminase activity and its isoenzymes with disease activity in rheumatoid arthritis.
Correlations between matrix metalloproteinase-9 and adenosine deaminase isozymes in synovial fluid from patients with rheumatoid arthritis.
Effect of cyclosporin on the activity of cytidine deaminase and adenosine deaminase in the serum and polymorphonuclear leukocytes of patients with rheumatoid arthritis.
Plasma adenosine deaminase activity in children with rheumatic fever and rheumatoid arthritis.
Pleural fluid adenosine deaminase in rheumatoid arthritis and systemic lupus erythematosus.
Purine enzyme levels in rheumatoid arthritis.
Serum Adenosine Deaminase as Inflammatory Marker in Rheumatoid Arthritis.
Serum adenosine deaminase in patients with rheumatoid arthritis treated with methotrexate.
Serum Adenosine Deaminase Level is High But Not Related with Disease Activity Parameters in Patients with Rheumatoid Arthritis.
Serum adenosine deaminase may predict disease activity in rheumatoid arthritis.
Serum and synovial fluid adenosine deaminase activity in patients with rheumatoid arthritis, osteoarthritis, and reactive arthritis.
Serum interleukin-12, interleukin-15, soluble CD26, and adenosine deaminase in patients with rheumatoid arthritis.
Specific increase in enzymatic activity of adenosine deaminase 1 in rheumatoid synovial fibroblasts.
Three kinds of foamy cells in the spleen: comparative histochemical and ultrastructural studies.
[Aberrant over-expression of adenosine deaminase and its significance on rheumatoid arthritis]
[Adenosine deaminase activity in levamisole treatment of patients with rheumatoid arthritis]
Asthma
A genetic basis for heterogeneity of asthma syndrome in pediatric ages: adenosine deaminase phenotypes.
Aberrant purine metabolism in allergic asthma revealed by plasma metabolomics.
Adaptation to past malarial endemia and susceptibility to common diseases in modern populations: a study of adenosine deaminase and MN blood group genetic polymorphisms.
Adenosine deaminase and adenosine receptor polymorphisms in aspirin-intolerant asthma.
Alveolar-like Stem Cell-derived Myb(neg) Macrophages Promote Recovery and Survival in Airway Disease.
Cooperative effect of adenosine deaminase and ABO-secretor genetic complex on susceptibility to childhood asthma.
Genetic polymorphism and TH1/TH2 orientation.
Involvement of A1 adenosine receptors and neural pathways in adenosine-induced bronchoconstriction in mice.
The role of plasma adenosine deaminase in chemoattractant-stimulated oxygen radical production in neutrophils.
[Enzymes of purine metabolism of lymphocytes and eosinophiles in bronchial asthma]
[The effect of aminophylline on plasma oxypurines in patients with bronchial asthma or cor pulmonale]
Astrocytoma
Novel metabolic aspects related to adenosine deaminase inhibition in a human astrocytoma cell line.
The combination of adenosine deaminase inhibition and deoxyadenosine induces apoptosis in a human astrocytoma cell line.
Atherosclerosis
Extracellular Purine Metabolism in Blood Vessels (Part II): Activity of Ecto-Enzymes in Blood Vessels of Patients With Abdominal Aortic Aneurysm.
Increased activity of vascular adenosine deaminase in atherosclerosis and therapeutic potential of its inhibition.
Atrial Fibrillation
A novel association of adenosine deaminase with paroxysmal atrial fibrillation: a propensity score analysis from a case-control study.
Atrioventricular Block
Effect of adenosine on histamine release and atrioventricular conduction during guinea pig cardiac anaphylaxis.
On augmentation of adenosine-mediated negative dromotropic effect by K+ released during myocardial ischemia.
Autoimmune Diseases
Adenosine deaminase activity in plasma and blood cells of patients with haematological and autoimmune diseases.
Delayed onset adenosine deaminase deficiency associated with acute disseminated encephalomyelitis.
Polyserositis: a diagnostic challenge.
Serum adenosine deaminase activity is increased in systemic lupus erythematosus patients and correlated with disease activity.
[Pathogenetic significance of adenosine deaminase in autoimmune diseases]
Bacterial Infections
Significance of adenosine deaminase activity and its isoenzymes in tuberculous effusions.
The chondro-osseous dysplasia of adenosine deaminase deficiency with severe combined immunodeficiency.
The diagnostic and prognostic value of adenosine deaminase in tuberculous pericarditis.
[Clinical significance of cytokine measurement in pleural effusion]
Behcet Syndrome
Current concepts in the etiology and treatment of Behçet disease.
Bernard-Soulier Syndrome
A self-controlled comparative clinical trial to explore the effectiveness of three topical hemostatic agents for stopping severe epistaxis in pediatrics with inherited coagulopathies.
Blast Crisis
5'nucleotidase, adenosine deaminase and purine nucleoside phosphorylase activities in acute leukaemia.
A biological marker model for predicting disease transitions.
Adenosine deaminase activity in leukaemia.
Adenosine deaminase and ecto-5'-nucleotidase activities in various leukemias with special reference to blast crisis: significance of ecto-5'-nucleotidase in lymphoid blast crisis of chronic myeloid leukemia.
Differential expression of adenosine deaminase isozymes in acute leukemia.
[Certain biochemical features of leukocytes in blast crisis of chronic myelogenous leukemia]
[Enzymatic markers in chronic myeloleukemia and their importance for identifying a blast crisis]
Bone Diseases, Developmental
Partial resolution of bone lesions. A child with severe combined immunodeficiency disease and adenosine deaminase deficiency after enzyme-replacement therapy.
Bone Marrow Failure Disorders
Deficiency of adenosine deaminase 2 (DADA2) in Adults and Children: Experience from India.
Hematologic Manifestations of Deficiency of Adenosine Deaminase 2 (DADA2) and Response to Tumor Necrosis Factor Inhibition in DADA2-Associated Bone Marrow Failure.
Novel ADA2 mutation presenting with neutropenia, lymphopenia and bone marrow failure in patients with deficiency in adenosine deaminase 2 (DADA2).
Vasculopathy, Immunodeficiency, and Bone Marrow Failure: The Intriguing Syndrome Caused by Deficiency of Adenosine Deaminase 2.
Boutonneuse Fever
[Adenosine deaminase and boutonneuse fever]
[Serum adenosine deaminase activity in Mediterranean spotted fever]
Brain Diseases
Adenosine deaminase and protein pattern in serum and cerebrospinal fluid in experimental manganese encephalopathy.
Biallelic variants in ADARB1, encoding a dsRNA-specific adenosine deaminase, cause a severe developmental and epileptic encephalopathy.
Brain Infarction
[Juvenile familial vertebrobasilar brain infarctions due to adenosine deaminase 2 deficiency].
Brain Injuries
A1 adenosine receptors mediate hypoxia-induced ventriculomegaly.
Brain Ischemia
Neuroprotective effects of adenosine deaminase in the striatum.
Brain Neoplasms
Gene transfer and antisense nucleic acid techniques.
Hematopoietic stem cell gene therapy with drug resistance genes: an update.
Serum adenosine deaminase activity in brain tumours.
Breast Diseases
Diagnostic value of adenosine deaminase activity in benign and malignant breast tumors.
Breast Neoplasms
Activation of adenosine deaminase in MCF-7 cells through IGF-estrogen receptor alpha crosstalk.
Adenosine deaminase activity in the serum and malignant tumors of breast cancer: the assessment of isoenzyme ADA1 and ADA2 activities.
Adenosine deaminase inhibition suppresses progression of 4T1 murine breast cancer by adenosine receptor-dependent mechanisms.
Diagnostic value of adenosine deaminase activity in benign and malignant breast tumors.
Estrogen induces adenosine deaminase gene expression in MCF-7 human breast cancer cells: role of estrogen receptor-Sp1 interactions.
Hematopoietic stem cell gene therapy with drug resistance genes: an update.
Molecular characterization as a target for cancer therapy in relation to orphan status disorders (Review).
Oxidative stress and its relationship with adenosine deaminase activity in various stages of breast cancer.
Purine salvage enzyme activities in normal and neoplastic human tissues.
Serum adenosine deaminase, 5'-nucleotidase & alkaline phosphatase in breast cancer patients.
Urtica dioica inhibits cell growth and induces apoptosis by targeting Ornithine decarboxylase and Adenosine deaminase as key regulatory enzymes in adenosine and polyamines homeostasis in human breast cancer cell lines.
[Activity of the enzymes of DNA metabolism in the blood of patients with breast cancer]
[Lactate dehydrogenase, adenosine deaminase and thymidine phosphorylase activity of blood and tissues in breast tumor patients]
[Use of enzyme test in chemotherapy of patients with cancer of the breast]
Bronchitis, Chronic
[Changes in adenosine deaminase and antioxidative enzyme activity in patients with lung diseases of dust etiology]
Bronchopulmonary Dysplasia
Adenosine deaminase levels in premature infants with respiratory distress syndrome and bronchopulmonary dysplasia.
Brucellosis
Increased pleural fluid adenosine deaminase in brucellosis is difficult to differentiate from tuberculosis.
Primary peritonitis due to brucellosis mimicking tuberculous peritonitis.
[Activity of adenosine deaminase in acute brucellosis and complicated brucellosis]
Burkitt Lymphoma
Burkitt's lymphoma in a patient with adenosine deaminase deficiency-severe combined immunodeficiency treated with polyethylene glycol-adenosine deaminase.
Candidiasis
Properties of adenosine deaminase from Candida albicans.
Severe combined immunodeficiency disease with adenosine deaminase deficiency.
Carcinogenesis
Adenylic acid and adenosine deaminase activities in rat livers during azo-dye carcinogenesis.
Behaviour of adenylic acid and adenosine deaminase in spontaneous mammary carcinogenesis in mice.
Berries as chemopreventive dietary constituents--a mechanistic approach with the ApcMin/+ mouse.
The lymphocyte activity of adenosine deaminase and enzymes of AMP metabolism in mammary carcinogenesis: the effect of thymostimulin.
Three Nordic berries inhibit intestinal tumorigenesis in multiple intestinal neoplasia/+ mice by modulating beta-catenin signaling in the tumor and transcription in the mucosa.
[Influence of thymostimulin on the activity of certain enzymes of adenosine and AMP metabolism in lymphocytes of rats with mammary cancer]
Carcinoma
9-Deazaadenosine--a new potent antitumor agent.
A novel diagnostic method for distinguishing parapneumonic effusion and empyema from other diseases by using the pleural lactate dehydrogenase to adenosine deaminase ratio and carcinoembryonic antigen levels.
Activities of serum Ada, GGT and alp in carcinoma breast-a case control study for diagnostic and prognostic significance.
ADAR1 overexpression is associated with cervical cancer progression and angiogenesis.
Adenosine Deaminase - a Novel Diagnostic and Prognostic Biomarker for Oral Squamous Cell Carcinoma.
Adenosine deaminase activity in a transplantable murine renal adenocarcinoma.
Adenosine deaminase activity in gastric cancer.
Adenosine deaminase activity in patients with carcinoma of the bladder.
Adenosine deaminase activity in patients with renal adenocarcinoma.
Adenosine deaminase activity in patients with the intestinal type of gastric carcinoma.
Adenosine deaminase activity in peripheral lymphocytes of patients with gynaecologic malignancies.
Adenosine deaminase and purine nucleoside phosphorylase activities in peripheral blood cells of patients with neoplastic diseases. I. Bronchogenic carcinoma.
Adenosine deaminase and purine phosphorylase activities in lymphocytes and red blood cells of patients with carcinoma of the larynx.
Adenosine deaminase in saliva as a diagnostic marker of squamous cell carcinoma of tongue.
Adenosine deaminase, 5' nucleotidase, xanthine oxidase, superoxide dismutase, and catalase activities in cancerous and noncancerous human laryngeal tissues.
Adenosine deaminase, xanthine oxidase, superoxide dismutase, glutathione peroxidase activities and malondialdehyde levels in the sera of patients with head and neck carcinoma.
CD26 expression and adenosine deaminase activity in regulatory T cells (Treg) and CD4(+) T effector cells in patients with head and neck squamous cell carcinoma.
Characterization of adenosine deaminase from normal human epidermis and squamous cell carcinoma of the skin.
Diagnostic significance of adenosine deaminase, uric acid and C-reactive protein levels in patients of head and neck carcinoma.
Effects of 8-azaadenosine and formycin on cell lethality and the synthesis and methylation of nucleic acids in human colon carcinoma cells in culture.
Gastrointestinal tumor markers, other than carcinoembryonic antigen, and alpha fetal protein.
High adenosine deaminase level in pleural effusion due to bronchoalveolar carcinoma.
Oxidative stress and inflammatory response biomarkers in dogs with mammary carcinoma.
Purine enzyme profile in human colon-carcinoma cell lines and differential sensitivity to deoxycoformycin and 2'-deoxyadenosine in combination.
Purine metabolizing enzymes in lymphocytes from patients with solid tumors.
Reinforcement of antitumor effect of Cordyceps sinensis by 2'-deoxycoformycin, an adenosine deaminase inhibitor.
Role of downregulated ADARB1 in lung squamous cell carcinoma.
Serum Adenosine Deaminase Levels and Human Papillomavirus as Prognostic and Predictive Factors for Laryngeal and Pharyngeal Carcinomas.
Serum adenosine deaminase, 5'-nucleotidase & alkaline phosphatase in breast cancer patients.
Serum adenosine deaminase, catalase, and carbonic anhydrase activities in patients with renal cell carcinoma.
Studies of lymphocyte adenosine deaminase activity in patients with renal and transitional cell carcinoma.
Studies on purine enzymes in experimental colitis.
[Adenosine deaminase activity in hepatomas of varying degrees of malignancy]
[Adenosine metabolism in lymphocytes and neurochemical stressor reactions in mice with metastatic Lewis carcinoma after surgical removal of the tumor]
[Antimetastatic action of bacterial endotoxins and changes in the activity of the enzymes of purine metabolism in macrophages]
[Effect of GMDP encapsulated into liposomes on metastatic spread of Lewis lung carcinoma]
[Specificity of adenosine deaminase of living cancerous tissue of atypic rat epithelioma.]
[Use of the study of DNA metabolism enzyme activities as a test system in the treatment of breast cancer]
Carcinoma, Bronchogenic
Adenosine deaminase and purine nucleoside phosphorylase activities in peripheral blood cells of patients with neoplastic diseases. I. Bronchogenic carcinoma.
Role of biochemical tests in the diagnosis of exudative pleural effusions.
The association of adenosine deaminase activity with T-lymphocytes and subsets in pulmonary tuberculosis and bronchogenic carcinoma.
[Studies on the activity of adenosine deaminase in plasma in cancerous diseases with special regard to bronchial carcinoma.]
Carcinoma, Ehrlich Tumor
Cell proliferation in the thymus of Ehrlich ascites tumor bearing mice.
Synergistic effect of 3'-deoxyadenosine N1-oxide and adenosine deaminase inhibitors on growth of Ehrlich ascites tumor cells in vivo.
Carcinoma, Hepatocellular
Adenosine deaminase and adenosine kinase in rat hepatomas and kidney tumours.
Adenosine deaminase from deoxycoformycin-sensitive and -resistant rat hepatoma cells. Purification and characterization.
Adenosine deaminase gene amplification in deoxycoformycin-resistant mammalian cells.
Amplification of adenosine deaminase gene sequences in deoxycoformycin-resistant rat hepatoma cells.
Biochemical approaches to enhancement of antitumor drug selectivity: selective protection of cells from 6-thioguanine and 6-mercaptopurine by adenosine.
Chromosome anomalies associated with amplification of the adenosine deaminase gene (ADA) in rat hepatoma cells.
Circular RNA expression is suppressed by androgen receptor (AR)-regulated adenosine deaminase that acts on RNA (ADAR1) in human hepatocellular carcinoma.
Destabilization of the adenosine deaminase gene sequences in rat-rat somatic cell hybrids.
Increased adenosine deaminase synthesis and messenger RNA activity in deoxycoformycin-resistant cells.
Inhibition of hepatoma cell growth by analogs of adenosine and cyclic AMP and the influence of enzymes in mammalian sera.
Some biochemical mechanisms underlying the impairment of T and B cell immunity in C3HA mice during hepatoma growth.
[Adenosine deaminase activity in hepatomas of varying degrees of malignancy]
[Changes in DNA and purine nucleotide synthesis in lymphoid cells and sensitivity to glucocorticoids associated with the impairment of differentiation and immune function in mice during tumor growth. Spleen T- and B-lymphocytes]
[Changes in purine metabolism and in the immune response in the thymic and splenic lymphocytes of C3HA mice during chemical hepatocarcinogenesis]
[Changes in the lymphoid cells of DNA and purine nucleotide synthesis and sensitivity to glucocorticoids associated with impairment of differentiation and immune function during tumor growth in mice. Thymocytes]
Carcinoma, Lewis Lung
[Effect of GMDP encapsulated into liposomes on metastatic spread of Lewis lung carcinoma]
Carcinoma, Renal Cell
Adenosine deaminase activity in a transplantable murine renal adenocarcinoma.
Adenosine deaminase activity in patients with renal adenocarcinoma.
Serum adenosine deaminase, catalase, and carbonic anhydrase activities in patients with renal cell carcinoma.
Carcinoma, Small Cell
A novel diagnostic method for distinguishing parapneumonic effusion and empyema from other diseases by using the pleural lactate dehydrogenase to adenosine deaminase ratio and carcinoembryonic antigen levels.
Carcinoma, Squamous Cell
A novel diagnostic method for distinguishing parapneumonic effusion and empyema from other diseases by using the pleural lactate dehydrogenase to adenosine deaminase ratio and carcinoembryonic antigen levels.
ADAR1 overexpression is associated with cervical cancer progression and angiogenesis.
Adenosine Deaminase - a Novel Diagnostic and Prognostic Biomarker for Oral Squamous Cell Carcinoma.
Adenosine deaminase in saliva as a diagnostic marker of squamous cell carcinoma of tongue.
Adenosine deaminase, 5' nucleotidase, xanthine oxidase, superoxide dismutase, and catalase activities in cancerous and noncancerous human laryngeal tissues.
CD26 expression and adenosine deaminase activity in regulatory T cells (Treg) and CD4(+) T effector cells in patients with head and neck squamous cell carcinoma.
Characterization of adenosine deaminase from normal human epidermis and squamous cell carcinoma of the skin.
Diagnostic significance of adenosine deaminase, uric acid and C-reactive protein levels in patients of head and neck carcinoma.
Role of downregulated ADARB1 in lung squamous cell carcinoma.
Carcinoma, Transitional Cell
Adenosine deaminase activity in patients with carcinoma of the bladder.
Studies of lymphocyte adenosine deaminase activity in patients with renal and transitional cell carcinoma.
Cardiomegaly
[The enzymatic activity of adenosine metabolism in the rat heart. The effects of cardiac hypertrophy]
Cauda Equina Syndrome
[Cauda equina syndrome with elevated adenosine deaminase in a patient with HIV infection]
Celiac Disease
DNA damage, oxidative stress, and inflammation in children with celiac disease.
Elevated adenosine deaminase levels in celiac disease.
Cerebral Infarction
Profile of tuberculous meningitis with or without HIV infection and the predicators of adverse outcome.
Cerebrovascular Disorders
Diagnostic value of cerebrospinal fluid adenosine deaminase determination.
Chagas Disease
ADENOSINE DEAMINASE ACTIVITY AND SERUM C-REACTIVE PROTEIN AS PROGNOSTIC MARKERS OF CHAGAS DISEASE SEVERITY.
E-NTPDase and E-ADA activities are altered in lymphocytes of patients with indeterminate form of Chagas' disease.
Chemical and Drug Induced Liver Injury
AMP deaminase and adenosine deaminase activities in liver and brain regions in acute ammonia intoxication and subacute toxic hepatitis.
Chickenpox
[Adenosine deaminase deficiency associated severe combined immunodeficiency with disseminated varicella infection after vaccination: a case report]
Cholecystitis, Acute
[Dynamics of the cytokines, homocysteine contents, indices of oxydative and nitrosative stress and cytopathic hypoxia in patients after cholecystectomy for acute cholecystitis. Connection with rate of postoperative purulent-inflammatory complications]
Cholelithiasis
[Enzymatic activity of serum adenosine deaminase in different liver disorders]
Cholera
Evaluation of adenosine or related nucleosides as physiological regulators of lipolysis in adipose tissue.
Inhibition of lipolysis and cyclic AMP accumulation by adenosine analogues in hamster epididymal adipocytes exposed to cholera toxin.
Chordoma
Overexpression of adenosine deaminase acting on RNA 1 in chordoma tissues is associated with chordoma pathogenesis by reducing miR?125a and miR?10a expression.
Choriocarcinoma
Increased expression of one of two adenosine deaminase alleles in a human choriocarcinoma cell line following selection with adenine nucleosides.
coagulation factor viia deficiency
A self-controlled comparative clinical trial to explore the effectiveness of three topical hemostatic agents for stopping severe epistaxis in pediatrics with inherited coagulopathies.
Coccidioidomycosis
Coccidioidomycosis: ADA levels, serologic parameters, culture results, and PCR testing in pleural fluid.
Coinfection
Serum Adenosine Deaminase (ADA) Activity: A Novel Screening Test to Differentiate HIV Monoinfection From HIV-HBV and HIV-HCV Coinfections.
Colitis
Blood purine and energy status in rats with colitis.
Inhibition of adenosine deaminase attenuates inflammation in experimental colitis.
The blockade of adenosine deaminase ameliorates chronic experimental colitis through the recruitment of adenosine A2A and A3 receptors.
Therapeutic potentials of adenosine receptors agonists and antagonists in colitis; Current status and perspectives.
Colitis, Ulcerative
Serum adenosine deaminase activity as a predictor of disease severity in ulcerative colitis.
Colonic Neoplasms
Adenosine suppresses CW2 human colonic cancer growth by inducing apoptosis via A(1) adenosine receptors.
Effects of aqueous green tea extract on activities of DNA turn-over enzymes in cancerous and non-cancerous human gastric and colon tissues.
Genetic variability within Adenosine Deaminase gene and uterine leiomyomas.
Colorectal Neoplasms
Activities of adenosine deaminase and 5'-nucleotidase in cancerous and noncancerous human colorectal tissues.
Coma
Characteristic abnormalities in cerebrospinal fluid biochemistry in children with cerebral malaria compared to viral encephalitis.
Profile of tuberculous meningitis with or without HIV infection and the predicators of adverse outcome.
Common Variable Immunodeficiency
Adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency in common variable immunodeficiency.
Epstein-Barr virus-induced lymphoblastoid cell lines from patients with primary immunodeficiency diseases.
Communicable Diseases
Serum adenosine deaminase and xanthine oxidase activities in silver catfish naturally infected with Ichthyophthirius multifiliis: The influence of these enzymes on inflammatory and oxidative status.
Congenital Abnormalities
Enzymatic and extraenzymatic role of adenosine deaminase 1 in T-cell-dendritic cell contacts and in alterations of the immune function.
Enzymatic and extraenzymatic role of ecto-adenosine deaminase in lymphocytes.
The molecular genetics of pediatric lipid disorders: recent progress and future research directions.
[Adenosine deaminase as costimulatory molecule and marker of cellular immunity].
Contracture
Adenosine reduces the reverse mode of the Na+/Ca(2+) exchanger in ferret cardiac fibres.
Effects of endogenous adenosine and adenosine receptor agonists on hypoxia-induced myocardial stunning in Guinea-pig atria and papillary muscles.
In vitro ischaemic preconditioning of isolated rabbit cardiomyocytes: effects of selective adenosine receptor blockade and calphostin C.
Coronary Artery Disease
ADA*2 Allele of the Adenosine Deaminase Gene May Protect against Coronary Artery Disease.
Adenosine Deaminase Genetic Polymorphism and Coronary Artery Disease.
Coronary artery disease. A study of three polymorphic sites of adenosine deaminase gene.
Coronary artery disease: a study on the joint role of birth weight, adenosine deaminase, and gender.
Does adenosine deaminase play a key role in coronary artery disease.
Genetic Polymorphism of Adenosine Deaminase and Early Neonatal Events: Is There an Association with Susceptibility to Coronary Artery Disease in Adult Life?
Serum adenosine deaminase activity and coronary artery disease: a retrospective case-control study based on 9929 participants.
The interaction of ACP1, ADA1, diabetes and gender in coronary artery disease.
The role of plasma adenosine deaminase in chemoattractant-stimulated oxygen radical production in neutrophils.
Coronary Disease
Type-2 diabetes mellitus and the frequency of the G22A polymorphism of the adenosine deaminase gene in a mixed population in Brazil.
Coronary Occlusion
Augmentation of endogenous adenosine attenuates myocardial 'stunning' independently of coronary flow or hemodynamic effects.
Effect of adenosine deaminase inhibitors on myocardial reactive hyperaemia following brief coronary occlusions.
Effect of exogenous adenosine deaminase on arrhythmias and the release of adenine nucleotide catabolites in isolated rat hearts with coronary occlusion and reperfusion.
Effect of temperature on myocardial infarction in swine.
Role of adenosine in coronary blood flow regulation after reductions in perfusion pressure.
Role of adenosine in coronary vasodilation during exercise.
Role of adenosine in the maintenance of coronary vasodilation distal to a severe coronary artery stenosis. Observations in conscious domestic swine.
Coronavirus Infections
Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus.
Cough
Development of a clinical prediction rule for tuberculous meningitis in adults in Lima, Peru.
[Exploratory research on diagnostic essentials of pediatric tuberculous pleurisy].
Crohn Disease
Adaptation to past malarial endemia and susceptibility to common diseases in modern populations: a study of adenosine deaminase and MN blood group genetic polymorphisms.
Adenosine deaminase activity in patients with Crohn's disease: distinction between active and nonactive disease.
No Association Between Serum Adenosine Deaminase Activity and Disease Activity in Crohn's Disease.
Crush Syndrome
Activity of enzymes of adenyline compounds metabolism during crush and decompression of muscle tissue. Part II. Adenosine deaminase activity at experimental crush syndrome.
Cryopyrin-Associated Periodic Syndromes
Diagnostic utility of a targeted next-generation sequencing gene panel in the clinical suspicion of systemic autoinflammatory diseases: a multi-center study.
Cystic Fibrosis
Alveolar-like Stem Cell-derived Myb(neg) Macrophages Promote Recovery and Survival in Airway Disease.
Evaluation of Serum Adenosine Deaminase in Cystic Fibrosis Patients in an Iranian Referral Hospital.
Gene therapy for ovarian carcinoma.
Human gene therapy for hereditary diseases: a review of trials.
Towards gene therapy for the central nervous system.
Cysts
A rare presentation of splenic tuberculosis with a pseudocyst.
Analysis of the ectoenzymes ADA, ALP, ENPP1, and ENPP3, in the contents of ovarian endometriomas as candidate biomarkers of endometriosis.
Omental cyst presenting as tubercular ascites.
dctp diphosphatase deficiency
Inosine triphosphate pyrophosphohydrolase deficiency in a kindred with adenosine deaminase deficiency.
Deafness
Sensorineural deafness in siblings with adenosine deaminase deficiency.
Deficiency Diseases
Adenosine deaminase deficiency in combined immunologic deficiency disease.
Adenosine deaminase impairment and ribonucleotide reductase activity and levels in HeLa cells.
Bone marrow gene transfer in three patients with adenosine deaminase deficiency.
Effect of adenosine deaminase replacement therapy on a child of adenosine deaminase deficiency with severe combined immunodeficiency disease.
S-Adenosylhomocysteine hydrolase activity in a lymphoblastoid cell line from a patient with adenosine deaminase dificiency disease.
Treatment of adenosine deaminase deficiency.
Workshop on severe combined immunological deficiency disease and adenosine deaminase deficiency. Albany, New York, on October 1, 1973.
Dementia
Enhanced oral bioavailability of DDI after administration of 6-Cl-ddP, an adenosine deaminase-activated prodrug, to chronically catheterized rats.
Serum markers of monocyte/macrophage activation in patients with Alzheimer's disease and other types of dementia.
Dermatitis, Atopic
Insulin-dependent diabetes mellitus and severe atopic dermatitis in a child with adenosine deaminase deficiency.
Dermatitis, Contact
Adenosine deaminase levels in construction workers with asbestos contact dermatitis.
Dermatomyositis
A clinical score to guide in decision making for monogenic type I IFNopathies.
Diabetes Insipidus
The map of chromosome 20.
Diabetes Mellitus
A girl with diabetes and severe combined immunodeficiency from adenosine deaminase deficiency.
A study of three polymorphic sites of the ADA gene in children with type 1 diabetes mellitus.
Adenosine deaminase activity in the serum of type 2 diabetic patients.
Adenosine deaminase activity in type 2 diabetes mellitus: does it have any role?
Changes in Adenosine Deaminase Activity in Patients with Type 2 Diabetes Mellitus and Effect of DPP-4 Inhibitor Treatment on ADA Activity.
Correlation study of adenosine deaminase and its isoenzymes in type 2 diabetes mellitus.
Diagnostic Value of Adenosine Deaminase and Its Isoforms in Type II Diabetes Mellitus.
Disease-specific induced pluripotent stem cells.
Early-onset type 2 (non-insulin-dependent) diabetes mellitus is associated with glucokinase locus, but not with adenosine deaminase locus, in the Japanese population.
Effects of coenzyme Q10 supplementation on the serum levels of amylase, adenosine deaminase, catalase, and total antioxidant capacity in women with type 2 diabetes mellitus: A randomized, double-blind placebo-controlled trial.
Elevated adenosine deaminase activity in the serum of patients with diabetes mellitus.
Platelet aggregation and serum adenosine deaminase (ADA) activity in pregnancy associated with diabetes, hypertension and HIV.
Raised serum adenosine deaminase level in nonobese type 2 diabetes mellitus.
Type-2 diabetes mellitus and the frequency of the G22A polymorphism of the adenosine deaminase gene in a mixed population in Brazil.
Diabetes Mellitus, Experimental
Alloxan diabetes regulates adenosine deaminase activity in mice: tissue- and age-specific correlation.
[Characteristics of purine and nucleotide metabolism in juvenile rats with alloxan diabetes]
Diabetes Mellitus, Type 1
A study of three polymorphic sites of the ADA gene in children with type 1 diabetes mellitus.
Disease-specific induced pluripotent stem cells.
Effect of diabetes/hyperglycemia on the rat retinal adenosinergic system.
Immunotherapy for insulin-dependent diabetes mellitus in the "BB" rat.
Insulin-dependent diabetes mellitus and severe atopic dermatitis in a child with adenosine deaminase deficiency.
Long-term culture and T cell receptor analysis of T cell clones isolated from a patient with adenosine deaminase deficiency and type I diabetes.
Prevention of insulin-dependent diabetes mellitus by 2'-deoxycoformycin in the BB Wistar rat.
Diabetes Mellitus, Type 2
A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene.
Adenosine deaminase activity in type 2 diabetes mellitus: does it have any role?
Adenosine deaminase and body mass index in non-insulin-dependent diabetes mellitus.
Adenosine deaminase gene polymorphism is associated with obesity in Iranian population.
Changes in Adenosine Deaminase Activity in Patients with Type 2 Diabetes Mellitus and Effect of DPP-4 Inhibitor Treatment on ADA Activity.
Correlation study of adenosine deaminase and its isoenzymes in type 2 diabetes mellitus.
Early-onset type 2 (non-insulin-dependent) diabetes mellitus is associated with glucokinase locus, but not with adenosine deaminase locus, in the Japanese population.
Effects of coenzyme Q10 supplementation on the serum levels of amylase, adenosine deaminase, catalase, and total antioxidant capacity in women with type 2 diabetes mellitus: A randomized, double-blind placebo-controlled trial.
Exclusion of adenosine deaminase gene locus on chromosome 20q12-13.1 in familial NIDDM in Taiwanese patients.
Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q.
Genetic analysis of glucokinase and the chromosome 20 diabetes susceptibility locus in families with type 2 diabetes.
Raised serum adenosine deaminase level in nonobese type 2 diabetes mellitus.
Search for a third susceptibility gene for maturity-onset diabetes of the young. Studies with eleven candidate genes.
Sib-pair analysis of adenosine deaminase locus in NIDDM.
Type 2 diabetes and the genetics of signal transduction: a study of interaction between adenosine deaminase and acid phosphatase locus 1 polymorphisms.
[Diabetes mellitus and molecular biology]
Diabetes, Gestational
G22A Polymorphism of Adenosine Deaminase and its Association with Biochemical Characteristics of Gestational Diabetes Mellitus in an Iranian Population.
Maternal circulating levels of some metabolic syndrome biomarkers in gestational diabetes mellitus.
Serum adenosine deaminase activity in gestational diabetes mellitus and normal pregnancy.
Diabetic Retinopathy
Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage.
DiGeorge Syndrome
Epstein-Barr virus-induced lymphoblastoid cell lines from patients with primary immunodeficiency diseases.
dihydropyrimidinase deficiency
Application of metabolomic principles to disorders of nucleotide metabolism reveals new metabolic perturbations.
Dihydropyrimidine Dehydrogenase Deficiency
Application of metabolomic principles to disorders of nucleotide metabolism reveals new metabolic perturbations.
Disseminated Intravascular Coagulation
Effects of enrofloxacin, flunixin meglumine and dexamethasone on disseminated intravascular coagulation, cytokine levels and adenosine deaminase activity in endotoxaemia in rats +.
double-stranded rna adenine deaminase deficiency
RNA adenosine deaminase ADAR1 deficiency leads to increased activation of protein kinase PKR and reduced vesicular stomatitis virus growth following interferon treatment.
RNA editing of the Q/R site of GluA2 in different cultured cell lines that constitutively express different levels of RNA editing enzyme ADAR2.
Down Syndrome
Disease-specific induced pluripotent stem cells.
Elevated erythrocyte adenosine deaminase activity in Down's syndrome.
Erythrocyte adenosine deaminase, purine nucleoside phosphorylase and phosphoribosyltransferase activity in patients with Down's syndrome.
Levels of some purine metabolizing enzymes in lymphocytes from patients with Down's syndrome.
Duodenal Ulcer
Adenosine deaminase activity in the gastric mucosa of duodenal ulcer patients in relation to the severity of chronic gastritis and gastric acid secretion.
Duodenal ulcer and mucosal adenosine deaminase activity. Effects of ranitidine and sucralfate.
Mucosal adenosine deaminase activity and stump ulcer healing.
Dwarfism
The map of chromosome 20.
Dyspnea
Potential role of endogenous adenosine in ticagrelor-induced dyspnea.
Eclampsia
Relationship between erythrocyte catalase and serum adenosine deaminase activities in eclampsia.
Empyema
A continuous method for the estimation of adenosine deaminase catalytic concentration in pleural effusions with a Hitachi 705 discrete analyser.
A novel diagnostic method for distinguishing parapneumonic effusion and empyema from other diseases by using the pleural lactate dehydrogenase to adenosine deaminase ratio and carcinoembryonic antigen levels.
Evaluation of polymerase chain reaction and adenosine deaminase assay for the diagnosis of tuberculous effusions in children.
Immune status with empyema thoracis.
Risk factors for tuberculous empyema in pleural tuberculosis patients.
[Diagnosis and treatment of tuberculous pleurisy--with special reference to the significance of measurement of pleural fluid cytokines]
[Management of pleural disease].
Encephalitis
Cerebrospinal fluid adenosine deaminase activity for the diagnosis of tuberculous meningitis in children.
Elevated Adenosine Deaminase Levels in the Cerebrospinal Fluid in Immune Checkpoint Inhibitor-induced Autoimmune Encephalitis: A Report of Two Cases.
Encephalitis, Herpes Simplex
High levels of adenosine deaminase in a patient with herpetic encephalitis and initial negative PCR results.
Encephalitis, Viral
Characteristic abnormalities in cerebrospinal fluid biochemistry in children with cerebral malaria compared to viral encephalitis.
Encephalomyelitis
Delayed onset adenosine deaminase deficiency associated with acute disseminated encephalomyelitis.
Encephalomyelitis, Acute Disseminated
Delayed onset adenosine deaminase deficiency associated with acute disseminated encephalomyelitis.
Endometriosis
Analysis of the ectoenzymes ADA, ALP, ENPP1, and ENPP3, in the contents of ovarian endometriomas as candidate biomarkers of endometriosis.
Identification of global transcriptome abnormalities and potential biomarkers in eutopic endometria of women with endometriosis: A preliminary study.
Endotoxemia
Inhibiting adenosine deaminase modulates the systemic inflammatory response syndrome in endotoxemia and sepsis.
Inhibition of adenosine deaminase attenuates endotoxin-induced release of cytokines in vivo in rats.
Enteritis
Adenosine deaminase inhibition prevents Clostridium difficile toxin A-induced enteritis in mice.
Effect of novel A2A adenosine receptor agonist ATL 313 on Clostridium difficile toxin A-induced murine ileal enteritis.
Eosinophilia
Adenosine and adenosine receptors in the pathomechanism and treatment of respiratory diseases.
Epilepsy
Adenosine deaminase and adenosine kinase expression in human glioma and their correlation with glioma?associated epilepsy.
Effects of progesterone on total brain tissue adenosine deaminase activity in experimental epilepsy.
Novel exon of mammalian ADAR2 extends open reading frame.
Epstein-Barr Virus Infections
Prognostic Value of Blood-Based Inflammatory Biomarkers in Secondary Hemophagocytic Lymphohistiocytosis.
Essential Hypertension
The role of adenosine-related genes variants in susceptibility to essential hypertension.
[Value of oxypurines and uric acid in plasma, renal excretion of oxypurines and uric acid as well as plasma adenosine deaminase and AMP deaminase activity in patients with essential hypertension]
Exanthema
A homozygote novel L451W mutation in CECR1 gene causes deficiency of adenosine deaminase 2 in a pediatric patient representing with chronic lymphoproliferation and cytopenia.
ADA2 Deficiency Mimicking Idiopathic Multicentric Castleman Disease.
Clinical and Laboratory Predictors associated with Complicated Scrub Typhus.
Monogenic polyarteritis: the lesson of ADA2 deficiency.
Exfoliation Syndrome
The Activities of Paraoxonase, Xanthine Oxidase, Adenosine Deaminase and the Level of Nitrite in Pseudoexfoliation Syndrome.
Fabry Disease
Management of Gaucher disease in a post-communist transitional health care system: Croatian experience.
Factor VII Deficiency
A self-controlled comparative clinical trial to explore the effectiveness of three topical hemostatic agents for stopping severe epistaxis in pediatrics with inherited coagulopathies.
Familial Mediterranean Fever
Autoinflammatory diseases in childhood, part 1: monogenic syndromes.
Diagnostic utility of a targeted next-generation sequencing gene panel in the clinical suspicion of systemic autoinflammatory diseases: a multi-center study.
Growth Parameters of Turkish Children With an Autoinflammatory Disease Before and After Canakinumab Treatment.
Old Dogs, New Tricks: Monogenic Autoinflammatory Disease Unleashed.
Serum adenosine deaminase activities during acute attacks and attack-free periods of familial Mediterranean fever.
Fanconi Syndrome
Pearson bone marrow-pancreas syndrome with insulin-dependent diabetes, progressive renal tubulopathy, organic aciduria and elevated fetal haemoglobin caused by deletion and duplication of mitochondrial DNA.
Fibromyalgia
Serum activities of adenosine deaminase, dipeptidyl peptidase IV and prolyl endopeptidase in patients with fibromyalgia: diagnostic implications.
Fibrosarcoma
Blood plasma adenosine deaminase in rats with fibrosarcoma.
Focal Epithelial Hyperplasia
Late-onset adenosine deaminase deficiency presenting with Heck's disease.
Food Hypersensitivity
Food allergy in a patient with adenosine deaminase deficiency undergoing enzyme replacement with polyethylene glycol-modified adenosine deaminase.
Foot-and-Mouth Disease
High-titer bicistronic retroviral vectors employing foot-and-mouth disease virus internal ribosome entry site.
Foramen Ovale, Patent
Ischemic Stroke in Young Adults.
Galactosemias
Evaluation of the expanded newborn screening program in New York City.
Gastritis
Adenosine deaminase activity in the gastric mucosa of duodenal ulcer patients in relation to the severity of chronic gastritis and gastric acid secretion.
Adenosine deaminase, 5'-nucleotidase, xanthine oxidase, superoxide dismutase, and catalase activities in gastric juices from patients with gastric cancer, ulcer, and atrophic gastritis.
Mucosal adenosine deaminase activity and gastritis histology: a comparative study of partially resected and intact stomachs.
Gastritis, Atrophic
Adenosine deaminase, 5'-nucleotidase, xanthine oxidase, superoxide dismutase, and catalase activities in gastric juices from patients with gastric cancer, ulcer, and atrophic gastritis.
An indication for correlation between the serum ADA level and gastric cancer risk.
Gastrointestinal Diseases
Caspase-4 activation in association with decreased adenosine deaminase activity may be a factor for gastric ulcer.
GATA2 Deficiency
Adenosine deaminase type 2 deficiency masquerading as GATA2 deficiency: Successful hematopoietic stem cell transplantation.
Gaucher Disease
Disease-specific induced pluripotent stem cells.
Management of Gaucher disease in a post-communist transitional health care system: Croatian experience.
Towards gene therapy for the central nervous system.
Genetic Diseases, Inborn
Adenosine Deaminase Two and Immunoglobulin M Accurately Differentiate Adult Sneddon's Syndrome of Unknown Cause.
An in vivo model of somatic cell gene therapy for human severe combined immunodeficiency.
Disease-specific induced pluripotent stem cells.
Gene therapy for cystic fibrosis.
Gene therapy for severe combined immunodeficiency caused by adenosine deaminase deficiency: improved retroviral vectors for clinical trials.
Gene therapy in infants with severe combined immunodeficiency.
Gene therapy in peripheral blood lymphocytes and bone marrow for ADA- immunodeficient patients.
Human gene therapy for hereditary diseases: a review of trials.
Human gene therapy in gastrointestinal diseases: in vivo and in vitro approaches.
Metabolic and immunologic consequences of limited adenosine deaminase expression in mice.
Mutations in the human adenosine deaminase gene that affect protein structure and RNA splicing.
Towards gene therapy for the central nervous system.
Transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA-deficient SCID.
[Values and limits of adenoviral vectors for gene transfer in vivo]
Giant Cell Arteritis
A Rare Case of Adenosine Deaminase 2 Deficiency Presenting With Temporal Arteritis.
Glioblastoma
Adenosine Deaminase That Acts on RNA 3 (ADAR3) Binding to Glutamate Receptor Subunit B Pre-mRNA Inhibits RNA Editing in Glioblastoma.
Glioma
ADAR3 expression is an independent prognostic factor in lower-grade diffuse gliomas and positively correlated with the editing level of GRIA2Q607R.
Adenosine deaminase and adenosine kinase expression in human glioma and their correlation with glioma?associated epilepsy.
Growth inhibition of human glioma cells induced by 8-chloroadenosine, an active metabolite of 8-chloro cyclic adenosine 3':5'-monophosphate.
Glomerulonephritis
Aldolase and adenosine deaminase activity in lymphocytes of patients with glomerulonephritis.
[Guanine deaminase and adenosine deaminase activity in chronic glomerulonephritis]
Gout
Erythrocyte adenosine deaminase and purine nucleoside phosphorylase activity in gout.
Purine excretion by cultured skin fibroblasts from patients with abnormal purine metabolism.
Graft vs Host Disease
Engraftment and chimerism, particularly of T- and B-cells, in children undergoing allogeneic bone marrow transplantation.
Specific immunosuppressive effects of constant infusion of 2'-deoxycoformycin.
Standard pentostatin dose reductions in renal insufficiency are not adequate: selected patients with steroid-refractory acute graft-versus-host disease.
Gram-Positive Bacterial Infections
Pleural effusion adenosine deaminase: a candidate biomarker to discriminate between Gram-negative and Gram-positive bacterial infections of the pleural space.
Granuloma
The diagnostic yield of closed needle pleural biopsy in exudative pleural effusion: a retrospective 10-year study.
Tuberculous pleural effusion.
[A 67-year-old man with fever, night sweat and ascites].
Granulomatous Disease, Chronic
Advances of gene therapy for primary immunodeficiencies.
Gene Therapy Approaches to Immunodeficiency.
Gene therapy for monogenic disorders of the bone marrow.
Gene therapy for primary immunodeficiencies: current status and future prospects.
Gene Therapy for the Treatment of Primary Immune Deficiencies.
Gene therapy of genetic diseases and cancer.
Gene therapy of inherited immunodeficiencies.
Gene transfer into hematopoietic stem cells as treatment for primary immunodeficiency diseases.
Granulocyte colony-stimulating factor recruitment of CD34+ progenitors to peripheral blood: impaired mobilization in chronic granulomatous disease and adenosine deaminase--deficient severe combined immunodeficiency disease patients.
Lentiviral-mediated Genetic Correction of Hematopoietic and Mesenchymal Progenitor Cells From Fanconi Anemia Patients.
Progress in gene therapy for primary immunodeficiencies using lentiviral vectors.
Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity.
Ten years of gene therapy for primary immune deficiencies.
Update on gene therapy for immunodeficiencies.
[Current status and future prospects of stem cell gene therapy for primary immunodeficiency].
Graves Disease
[Adenosine deaminase isoenzymes in patients with Graves' disease]
Guillain-Barre Syndrome
Guillain-Barré syndrome and tularemia pleuritis with high adenosine deaminase activity in pleural fluid.
Hashimoto Disease
Expression of genes for certain enzymes of pyrimidine and purine salvage pathway in peripheral blood leukocytes collected from patients with Graves' or Hashimoto's disease.
Head and Neck Neoplasms
Evaluation of adenosine deaminase activity in patients with head and neck cancer.
Serum enzymes in head and neck cancer III.
Heart Failure
Evaluation of adenosine deaminase (ADA) isoenzymes activity and tumor necrosis factor-? (TNF?) concentration in chronic heart failure.
The adenosine deaminase gene polymorphism is associated with chronic heart failure risk in Chinese.
The diagnosis of pleural effusions.
[Clinical significance of cytokine measurement in pleural effusion]
Hematologic Diseases
[Adenosine deaminase and purine nucleoside phosphorylase of thrombocytes in various hematologic diseases]
[Adenosine deaminase in formed blood elements: distribution and properties in normal states and in various hematologic diseases]
[Platelet adenosine desaminase in various hematological diseases]
Hematologic Neoplasms
2 chlorodeoxyadenosine activity and cross resistance patterns in primary cultures of human hematologic neoplasms.
Adenosine deaminase activity in lymphocytes of normal persons, leukemic patients, and kidney-transplant recipients.
Clinical, pharmacologic, and immunologic effects of 2'-deoxycoformycin.
Metabolism and action of fludarabine phosphate.
[Adenosine deaminase and purine nucleoside phosphorylase activities of various cultured cell lines derived from human hematologic malignancies]
Hemoglobinuria
Biologic relevance of elevated red cell adenosine deaminase activity in myelodysplastic syndromes and paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Biologic relevance of elevated red cell adenosine deaminase activity in myelodysplastic syndromes and paroxysmal nocturnal hemoglobinuria.
Hemorrhagic Fever, Crimean
Determination of serum adenosine deaminase and xanthine oxidase levels in patients with crimean-congo hemorrhagic fever.
Hepatitis
Activation of AMP deaminase and adenosine deaminase in the liver during ammonia poisoning and hepatitis.
Adenosine deaminase activity in serum of patients with hepatitis - a useful tool in monitoring clinical status.
Adenosine deaminase and guanosine deaminase activities in sera of patients with viral hepatitis.
Disseminated infection with varicella-zoster virus vaccine strain presenting as hepatitis in a child with adenosine deaminase deficiency.
Editing of glutamate receptor B subunit ion channel RNAs by four alternatively spliced DRADA2 double-stranded RNA adenosine deaminases.
Effects of conserved RNA secondary structures on hepatitis delta virus genotype I RNA editing, replication, and virus production.
Serum adenosine deaminase, 5' nucleotidase and malondialdehyde in acute infective hepatitis.
Studies on the age dependent changes in serum adenosine deaminase activity and its changes in hepatitis.
Studies on the serum adenosine deaminase activity test in patients with hepatitis.
THE ACTIVITY OF ADENOSINE DEAMINASE IN THE BLOOD SERUM OF VIRAL HEPATITIS PATIENTS.
The fraction of RNA that folds into the correct branched secondary structure determines hepatitis delta virus type 3 RNA editing levels.
[Activity of adenosine deaminase in severe course of viral hepatitis]
[Adenosine deaminase activity in peripheral lymphocytes during acute viral hepatitis (preliminary data)]
[Adenosine deaminase activity in the serum in viral hepatitis in children]
[Enzymatic activity of serum adenosine deaminase in different liver disorders]
[Guanine and adenosine deaminase activities in blood serum in the course of viral hepatitis]
[Serum adenosine deaminase in acute viral hepatitis and chronic liver diseases]
Hepatitis B
Adenosine deaminase, acquired immunodeficiency syndrome (AIDS), and hepatitis B infection.
Hepatitis C
[Serum adenosine deaminase and hepatitis C virus infection]
Hepatitis, Autoimmune
Relationship between serum adenosine deaminase levels and liver histology in autoimmune hepatitis.
Hepatitis, Chronic
Clinicopathological analysis of alcoholic liver disease complicating chronic type C hepatitis.
Herpes Simplex
Adenosine deaminase in herpes simplex virus induced corneal stromal disease.
Antiviral activity in the rabbit cornea of adenine arabinoside, Ara-A 5' monophosphate, and hypoxanthine arabinoside; and interactions with adenosine deaminase inhibitor.
Antiviral activity of an adenosine deaminase inhibitor: decreased replication of herpes simplex virus.
Antiviral activity of arabinosyladenine and arabinosylhypoxanthine in herpes simplex virus-infected KB cells: selective inhibition of viral deoxyribonucleic acid synthesis in the presence of an adenosine deaminase inhibitor.
Carbocyclic arabinofuranosyladenine (cyclaradine): efficacy against genital herpes in guinea pigs.
Erythro-9-(2-hydroxy-3-nonyl) Adenine alone and in combination with 9-beta-D-arabinofuranosyladenine in treatment of systemic herpesvirus infections in mice.
Erythro-9-(2-hydroxy-3-nonyl)adenine as a specific inhibitor of herpes simplex virus replication in the presence and absence of adenosine analogues.
Herpes simplex virus mutants resistant to arabinosyladenine in the presence of deoxycoformycin.
Inhibition of herpes simplex virus replication by purine deoxyribonucleosides.
The antiherpesvirus activity and cytotoxicity of sangivamycin.
The antiviral activity of 9-beta-D-arabinofuranosyladenine is enhanced by the 2',3'-dideoxyriboside, the 2',3'-didehydro-2',3'-dideoxyriboside and the 3'-azido-2',3'-dideoxyriboside of 2,6-diaminopurine.
Herpes Zoster
Adenosine effects on hormone-stimulated steroidogenesis in isolated bovine adrenal zona fasciculata cells.
HIV Infections
Adenosine deaminase binding to human CD26 is inhibited by HIV-1 envelope glycoprotein gp120 and viral particles.
Adenosine signaling and adenosine deaminase regulation of immune responses: impact on the immunopathogenesis of HIV infection.
Depressed activities of purine enzymes in lymphocytes of patients infected with human immunodeficiency virus.
Diagnostic significance of immunoglobulins and adenosine deaminase in pleural effusion.
Diagnostic value of pleural fluid adenosine deaminase in tuberculous pleuritis with reference to HIV coinfection and a Bayesian analysis.
HIV-1 envelope gp120 and viral particles block adenosine deaminase binding to human CD26.
Plasma adenosine deaminase activity among HIV1 Clade C seropositives: relation to CD4 T cell population and antiretroviral therapy.
Serum Adenosine Deaminase and Total Immunoglobulin G Correlate with Markers of Immune Activation and Inversely with CD4 Counts in Asymptomatic, Treatment-Naive HIV Infection.
Usefulness of Adenosine Deaminase Assay in Diagnosis of Patients with HIV Infection and Pleural Tuberculosis.
[Cauda equina syndrome with elevated adenosine deaminase in a patient with HIV infection]
[Serum adenosine deaminase and HIV infection]
Hodgkin Disease
Action of levamisole on E-rosette forming cells and serum adenosine deaminase in Hodgkin's disease.
Blood lymphocytes in chronic lymphocytic leukaemia and Hodgkin's disease: Immunological features and enzymes of nucleoside metabolism.
CD26, together with cell surface adenosine deaminase, is selectively expressed on ALK-positive, but not on ALK-negative, anaplastic large cell lymphoma and Hodgkin's lymphoma.
Decreased adenosine deaminase (ADA) and 5'nucleotidase (5NT) activity in peripheral blood T cells in Hodgkin disease.
[Adenosine deaminase activity in Hodgkin's disease (author's transl)]
[Decreased adenosine deaminase activity in the T-lymphocytes in Hodgkin's disease]
Homocystinuria
Evaluation of the expanded newborn screening program in New York City.
Huntington Disease
Disease-specific induced pluripotent stem cells.
Hydatidiform Mole
Increased adenosine deaminase in hydatidiform mole.
Hydrocephalus
Pearls & Oy-sters: chronic mumps meningoencephalitis with low CSF glucose and acute hydrocephalus in an adult.
Profile of tuberculous meningitis with or without HIV infection and the predicators of adverse outcome.
Hydronephrosis
[Diamond-Blackfan anemia confirmed by RPS19 gene mutation analysis: a case study and literature review of Korean patients]
Hydrothorax
CD4(+)CD25(-)Foxp3(+) T cells play a role in tuberculous hydrothorax rather than malignant hydrothorax.
Hyperalgesia
Antinociception by adenosine analogs and inhibitors of adenosine metabolism in an inflammatory thermal hyperalgesia model in the rat.
Antinociceptive and anti-inflammatory properties of an adenosine kinase inhibitor and an adenosine deaminase inhibitor.
Exogenous and endogenous adenosine enhance the spinal antiallodynic effects of morphine in a rat model of neuropathic pain.
RNA editing enzyme ADAR2 is a mediator of neuropathic pain after peripheral nerve injury.
Hypercholesterolemia
Enzymes that hydrolyze adenine nucleotides in a model of hypercholesterolemia induced by Triton WR-1339: protective effects of ?-caryophyllene.
Hyperemesis Gravidarum
Alterations in lipid peroxidation and T-cell function in women with hyperemesis gravidarum.
Serum adenosine deaminase activity in women with hyperemesis gravidarum.
Serum levels of adenosine deaminase and pregnancy-related hormones in hyperemesis gravidarum.
Hyperemia
Adenosine deaminase attenuates norepinephrine-induced coronary functional hyperemia.
Adenosine deaminase inhibitors enhance cerebral anoxic hyperemia in the rat.
Adenosine modulates reactive hyperemia in rat gut.
Autoregulation of the coronary circulation.
Effect of adenosine deaminase on myocardial reactive hyperemia: preliminary report.
Intracoronary adenosine deaminase reduces canine myocardial reactive hyperemia.
Multifactorial mediation of post norepinephrine induced intestinal hyperemia.
Relative participation of adenosine and endothelium derived mediators in coronary reactive hyperemia in the dog.
Role of adenosine for reactive hyperemia in normal and stunned porcine myocardium.
Role of adenosine in coronary blood flow regulation after reductions in perfusion pressure.
Role of adenosine in coronary vasodilation during exercise.
Role of adenosine in postprandial and reactive hyperemia in canine jejunum.
Short-time adenosine deaminase interventions upon underperfused rat hearts in vitro--a test for the role of adenosine in the coronary flow control.
Systemic adenosine deaminase administration does not reduce active hyperemia in running rats.
The role of adenosine in glycine-induced glomerular hyperfiltration in rats.
Hyperglycemia
Effect of diabetes/hyperglycemia on the rat retinal adenosinergic system.
Hyperglycemia alters E-NTPDases, ecto-5'-nucleotidase, and ectosolic and cytosolic adenosine deaminase activities and expression from encephala of adult zebrafish (Danio rerio).
Hyperhomocysteinemia
[Effect of thiolactone homocysteine loading on adenosine metabolism in rats: relationship with platelet hyper-reactivity, correction of this metabolism disorders by vitamin-microelement complex]
Hyperlipoproteinemia Type II
Human gene therapy for hereditary diseases: a review of trials.
Towards gene therapy for the central nervous system.
Hyperoxaluria, Primary
Complete adenosine deaminase (ADA) deficiency without immunodeficiency, and primary hyperoxaluria, in a 12-year-old boy.
Primary hyperoxaluria and adenosine deaminase deficiency without immunodeficiency.
Hypersensitivity
Adenosine deaminase levels in construction workers with asbestos contact dermatitis.
Anti-inflammatory activity of non-nucleoside adenosine deaminase inhibitor FR234938.
Biomarkers of Cutaneous Leishmaniasis.
Sustained Elevated Adenosine via ADORA2B Promotes Chronic Pain through Neuro-immune Interaction.
Hypertension
A 9.5-year-old boy with recurrent neurological manifestations and severe hypertension, treated initially for polyarteritis nodosa, was subsequently diagnosed with adenosine deaminase type 2 deficiency (DADA2) which responded to anti-TNF-?.
Adenosine deaminase activity in subjects with normal pregnancy, pregnancy induced hypertension and pre-eclampsia.
Effects of adenosine deaminase inhibition on blood pressure in old spontaneously hypertensive rats.
Intrarenal adenosine produces hypertension via renal nerves in the one-kidney, one clip rat.
Platelet aggregation and serum adenosine deaminase (ADA) activity in pregnancy associated with diabetes, hypertension and HIV.
Smoking and hypertension: Effect of adenosine deaminase polymorphism.
Swimming training prevents alterations in ecto-NTPDase and adenosine deaminase activities in lymphocytes from N?-nitro-L-arginine methyl ester hydrochloride induced hypertension rats.
Hypertension, Portal
[Adenosine deaminase activity in peritoneal tuberculosis]
Hypertension, Pregnancy-Induced
Adenosine deaminase activity in subjects with normal pregnancy, pregnancy induced hypertension and pre-eclampsia.
Hyperthyroidism
Adenosine deaminase inhibition enhances the inotropic response mediated by A1 adenosine receptor in hyperthyroid guinea pig atrium.
Effect of thyroid status on alpha- and beta-catecholamine responsiveness of hamster adipocytes.
Hyperthyroidism increases adenosine transport and metabolism in the rat heart.
Hypothyroidism and hyperthyroidism change ectoenzyme activity in rat platelets.
Reduced binding and antilipolytic effect of prostaglandin E2 in adipocytes from patients with hyperthyroidism.
Short-term hyperthyroidism modulates adenosine receptors and catalytic activity of adenylate cyclase in adipocytes.
The effect of adenosine deaminase inhibition on the A1 adenosinergic and M2 muscarinergic control of contractility in eu- and hyperthyroid guinea pig atria.
[The effect of somatotropin on adenosine deaminase activity in tissues of rats with hypo- and hyperthyroidism]
Hypotension
Oxygen-dependent mechanisms in cerebral autoregulation.
Hypothyroidism
Autoimmune thyroiditis and acquired hypothyroidism in an infant with severe combined immunodeficiency due to adenosine deaminase deficiency.
Changes in the activities of adenosine-metabolizing enzymes in six regions of the rat brain on chemical induction of hypothyroidism.
Effect of adenosine deaminase, N6-phenylisopropyladenosine and hypothyroidism on the responsiveness of rat brown adipocytes to noradrenaline.
Enzymes involved in adenosine metabolism in rat white and brown adipocytes. Effects of streptozotocin-diabetes, hypothyroidism, age and sex differences.
Hypothyroidism and hyperthyroidism change ectoenzyme activity in rat platelets.
Hypothyroidism Enhanced Ectonucleotidases and Acetylcholinesterase Activities in Rat Synaptosomes can be Prevented by the Naturally Occurring Polyphenol Quercetin.
Quercetin changes purinergic enzyme activities and oxidative profile in platelets of rats with hypothyroidism.
hypoxanthine phosphoribosyltransferase deficiency
Substrate inhibition of adenosine phosphorylation in adenosine deaminase deficiency and adenosine-mediated inhibition of PP-ribose-P dependent nucleotide synthesis in hypoxanthine phosphoribosyltransferase deficient erythrocytes.
Two-dimensional thin-layer chromatography for the screening of disorders of purine and pyrimidine metabolism.
Use of intact erythrocytes in the diagnosis of inherited purine and pyrimidine disorders.
Ileitis
Feed-forward inhibition of CD73 and upregulation of adenosine deaminase contribute to the loss of adenosine neuromodulation in postinflammatory ileitis.
Immune System Diseases
First trimester diagnosis of Lesch-Nyhan syndrome: applications to other disorders of purine metabolism.
Gene therapy for inherited immunodeficiencies.
Vascular complications and gene therapy.
Immunoglobulin G4-Related Disease
IgG4-related disease manifesting as pericarditis with elevated adenosine deaminase and IL-10 levels in pericardial fluid.
IgG4-related disease with elevated adenosine deaminase in pleural effusion diagnosed clinically using thoracoscopy under local anesthesia and FDG-PET-CT.
IgG4-related Pleuritis with Elevated Adenosine Deaminase in Pleural Effusion: A Case Report.
Long-term spontaneous remission with active surveillance in IgG4-related pleuritis: A case report and literature review.
Infarction, Middle Cerebral Artery
[The role of adenosine deaminase in the electroacupuncture preconditioning induced rapid tolerance to focal cerebral ischemia].
Infections
A case of Strongyloides hyperinfection associated with tuberculosis.
A study on the status of inflammatory systems in camels naturally infected with Toxoplasma gondii.
Activity of the enzyme adenosine deaminase in serum, erythrocytes and lymphocytes of rats infected with Trypanosoma evansi.
ADAR2 Is Involved in Self and Nonself Recognition of Borna Disease Virus Genomic RNA in the Nucleus.
Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus.
Adenosine deaminase deficiency with late onset of recurrent infections: response to treatment with polyethylene glycol-modified adenosine deaminase.
Adenosine deaminase in malaria infection: effect of 2'-deoxycoformycin in vivo.
Adenosine deaminase isoenzyme levels in patients with human T-cell lymphotropic virus type 1 and human immunodeficiency virus type 1 infections.
Adenosine deaminase isoenzymes and HIV/HTLV-1 infections.
Adenosine deaminase isoenzymes in typhoid fever.
Adenosine deaminase regulates Treg expression in autologous T cell-dendritic cell cocultures from patients infected with HIV-1.
Adenosine deaminase, acquired immunodeficiency syndrome (AIDS), and hepatitis B infection.
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID.
Antischistosomal and liver protective effects of Curcuma longa extract in Schistosoma mansoni infected mice.
Biomarkers of Cutaneous Leishmaniasis.
Comparison of an adenosine deaminase assay with ELISA for the diagnosis of tuberculous meningitis infection.
Concurrent small bowel lymphoma and mycobacterial infection: use of adenosine deaminase activity and polymerase chain reaction to facilitate rapid diagnosis and treatment.
Conversion of asymptomatic infection to symptomatic visceral leishmaniasis: A study of possible immunological markers.
Critical Role for the Adenosine Pathway in Controlling Simian Immunodeficiency Virus-Related Immune Activation and Inflammation in Gut Mucosal Tissues.
Curcumin pre-treatment modulate the activities of adenine nucleotide and nucleoside degradation enzymes in lymphocyte of rats infected with Trypanosoma evansi.
Cutaneous polyarteritis nodosa successfully treated with topical diflucortolone valerate--a case report & review of the literature.
Diagnostic Performance of Pleural Fluid Adenosine Deaminase for Tuberculous Pleural Effusion in a Low-Incidence Setting.
Disseminated infection with varicella-zoster virus vaccine strain presenting as hepatitis in a child with adenosine deaminase deficiency.
Double-stranded RNA adenosine deaminase activity during measles virus infection.
Ectonucleotidases and adenosine deaminase activity in laying hens naturally infected by Salmonella Gallinarum and their effects on the pathogenesis of the disease.
Efficient gene transfer into primary murine lymphocytes obviating the need for drug selection.
Efficient, low-cost protein factories: expression of human adenosine deaminase in baculovirus-infected insect larvae.
Elevated Adenosine Deaminase in Pleural Effusion A Case of Non-Hodgkin Lymphoma Misdiagnosis.
Enhancement of erythrocytic adenosine deaminase following treatment of AIDS-related complex/AIDS patients with zidovudine.
Erythro-9-(2-hydroxy-3-nonyl) Adenine alone and in combination with 9-beta-D-arabinofuranosyladenine in treatment of systemic herpesvirus infections in mice.
Experimental infection of cattle with Listeria monocytogenes: Participation of purinergic metabolism in disease pathogenesis.
Expression of human adenosine deaminase in murine hematopoietic cells.
Expression of interferon-inducible RNA adenosine deaminase ADAR1 during pathogen infection and mouse embryo development involves tissue-selective promoter utilization and alternative splicing.
Extracellular adenosine modulates host-pathogen interactions through regulation of systemic metabolism during immune response in Drosophila.
Genome-block expression-assisted association studies discover malaria resistance genes in Anopheles gambiae.
Glaxo/MRS Young Investigator Medal. Molecular studies on adenosine deaminase deficiency and hereditary haemorrhagic telangiectasia.
Host resistance to murine malaria in mice exposed to the adenosine deaminase inhibitor, 2'-deoxycoformycin.
IgG4-related disease manifesting as pericarditis with elevated adenosine deaminase and IL-10 levels in pericardial fluid.
IL-17 receptor A and adenosine deaminase 2 deficiency in siblings with recurrent infections and chronic inflammation.
Impacts of Escherichia coli infection in young breeder chicks on the animal behavior and cerebral activity of purinergic and cholinergic enzymes involved in the regulation of molecules with neurotransmitter and neuromodulator function.
Improving the accuracy of synovial fluid analysis in the diagnosis of prosthetic joint infection with simple and inexpensive biomarkers: C-reactive protein and adenosine deaminase.
Increased plasma adenosine deaminase activity in the early phase of Legionella pneumophila infection in guinea pigs.
Insulin-dependent diabetes mellitus and severe atopic dermatitis in a child with adenosine deaminase deficiency.
Long-term expression of human adenosine deaminase in mice after transplantation of bone marrow infected with amphotropic retroviral vectors.
Lymphocytic ascites with high adenosine deaminase levels secondary to Chlamydia trachomatis infection.
Mucosal adenosine deaminase activity and gastritis histology: a comparative study of partially resected and intact stomachs.
Neuroprotective role of resveratrol mediated by purinergic signalling in cerebral cortex of mice infected by Toxoplasma gondii.
Optimising the utility of pleural fluid adenosine deaminase for the diagnosis of adult tuberculous pleural effusion in Hong Kong.
Pearls & Oy-sters: chronic mumps meningoencephalitis with low CSF glucose and acute hydrocephalus in an adult.
Pearls and myths in pleural fluid analysis.
Plasma Adenosine Deaminase Enzyme Reduces with Treatment of Pulmonary Tuberculosis in Nigerian Patients: Indication for Diagnosis and Treatment Monitoring.
Prognostic significance of adenosine deaminase determinations in subjects with the lymphoadenopathy syndrome.
Properties of adenosine deaminase from Candida albicans.
Protamine sulfate as an effective alternative to polybrene in retroviral-mediated gene-transfer: implications for human gene therapy.
Role of Adenosine Deaminase in Common Chronic ENT Infections.
Sensorineural deafness in siblings with adenosine deaminase deficiency.
Serum adenosine deaminase 2 and neopterin levels are increased in a majority of hemophiliacs irrespective of infection with human immunodeficiency virus type 1.
Serum adenosine deaminase levels in intravenous drug users with and without infection due to human immunodeficiency virus.
Significance of adenosine deaminase measurement in sera of patients with HIV-1 infection.
Successful lectin-separated bone marrow transplantation in adenosine deaminase deficiency-related severe immunodeficiency.
Synovial fluid adenosine deaminase activity to diagnose tuberculous septic arthritis.
The predictive value of several markers in the progression to acquired immunodeficiency syndrome.
Tissue selectivity of interferon-stimulated gene expression in mice infected with Dam(+) versus Dam(-) Salmonella enterica serovar Typhimurium strains.
Transthyretin as a potential biomarker for the differential diagnosis between lung cancer and lung infection.
Treatment of African trypanosomiasis with cordycepin and adenosine deaminase inhibitors in a mouse model.
Treatment of respiratory viral infection in an immunodeficient infant with ribavirin aerosol.
Tuberculous pleurisy mimicking Mycoplasma pneumoniae infection in a previously healthy young adult: A case report.
Two cases of tuberculous peritonitis with liver cirrhosis complicated by refractory ascites.
Usefulness of Adenosine Deaminase Assay in Diagnosis of Patients with HIV Infection and Pleural Tuberculosis.
[A case of systemic IgG4-related disease with bilateral pleural effusions].
[Adenosine deaminase deficiency associated severe combined immunodeficiency with disseminated varicella infection after vaccination: a case report]
[Adenosine deaminase in differential diagnosis of peripheral lymph node tuberculosis]
[Further contribution to the study of the adenosine deaminase activity of the blood during typhoid infection]
[Study of serum adenosine deaminase activity in typhoid infection]
Infectious Mononucleosis
Adenosine deaminase, purine nucleoside phosphorylase and 5'-nucleotidase activities in infectious mononucleosis.
Infertility
Sperm DNA Integrity in Leukocytospermia and Its Association with Seminal Adenosine Deaminase.
Inflammatory Bowel Diseases
Adenosine Deaminase as a Useful Biomarker for Diagnosis and Monitoring of Inflammatory Bowel Disease.
Adenosine deaminase in the modulation of immune system and its potential as a novel target for treatment of inflammatory disorders.
Studies on purine enzymes in experimental colitis.
Insulin Resistance
Alterations in response of rat white adipocytes to insulin, noradrenaline, corticotropin and glucagon after adrenalectomy. Correction of these changes by adenosine deaminase.
Cellular cyclic AMP levels modulate insulin sensitivity and responsiveness--evidence against a significant role of Gi in insulin signal transduction.
Effect of adenosine deaminase and an adenosine analogue on insulin sensitivity in soleus muscle of the rat.
Effects of coenzyme Q10 supplementation on the serum levels of amylase, adenosine deaminase, catalase, and total antioxidant capacity in women with type 2 diabetes mellitus: A randomized, double-blind placebo-controlled trial.
Effects of insulin and norepinephrine on glucose transport and metabolism in rat brown adipocytes. Potentiation by insulin of norepinephrine-induced glucose oxidation.
In vitro effect of adenosine agonist GR79236 on the insulin sensitivity of glucose utilisation in rat soleus and human rectus abdominus muscle.
Insulin resistance and depressed cardiac G6PD activity induced by glucocorticoid exposure during pregnancy are attenuated by maternal estrogen-progestin therapy.
Insulin-induced subcellular redistribution of insulin-like growth factor II receptors in the rat adipose cell. Counterregulatory effects of isoproterenol, adenosine, and cAMP analogues.
Maternal circulating levels of some metabolic syndrome biomarkers in gestational diabetes mellitus.
Reversal of dietary-induced insulin resistance in muscle of the rat by adenosine deaminase and an adenosine-receptor antagonist.
Serum activities of dipeptidyl peptidase-4 and adenosine deaminase in polycystic ovary syndrome: association with obesity.
Suppression of uric acid and lactate production by sodium acetate ameliorates hepatic triglyceride accumulation in fructose-insulin resistant pregnant rats.
Syzygium cumini seed extract ameliorates adenosine deaminase activity and biochemical parameters but does not alter insulin sensitivity and pancreas architecture in a short-term model of diabetes.
The role of adenosine in insulin action coupling in rat adipocytes.
Intellectual Disability
Association of adenosine deaminase polymorphism with mild mental retardation.
Mutation in ADAT3, encoding adenosine deaminase acting on transfer RNA, causes intellectual disability and strabismus.
Novel Missense Variants in ADAT3 as a Cause of Syndromic Intellectual Disability.
Iron Overload
Iron overload as a result of transfusion therapy in a patient with adenosine deaminase deficiency.
Jaundice, Neonatal
Enzyme variability and neonatal jaundice. The role of adenosine deaminase and acid phosphatase.
Job Syndrome
Pattern recognitions receptors in immunodeficiency disorders.
Toll-like receptor signaling in primary immune deficiencies.
Keratitis
Chemotherapy of herpetic keratitis induced by acyclovir-resistant strains of herpes simplex virus type 1.
Kidney Failure, Chronic
Study of the activity of lymphocyte adenosine deaminase in chronic renal failure.
[Adenosine deaminase is useful for the diagnosis of peritoneal tuberculosis in patients with end-stage renal failure]
Kidney Neoplasms
The antigen identified by a mouse monoclonal antibody raised against human renal cancer cells is the adenosine deaminase binding protein.
Laryngeal Neoplasms
Adenosine deaminase and 5'-nucleotidase activities in saliva from patients with oral and laryngeal cancer.
Adenosine deaminase and purine phosphorylase activities in lymphocytes and red blood cells of patients with carcinoma of the larynx.
Serum adenosine deaminase and total superoxide dismutase activities before and after surgical removal of cancerous laryngeal tissue.
Leg Ulcer
Chronic leg ulcer revealing adenosine deaminase 2 deficiency: an atypical presentation.
Legionnaires' Disease
High adenosine deaminase activity in the pleural effusion of a patient with Legionnaires' disease.
Increased plasma adenosine deaminase activity in the early phase of Legionella pneumophila infection in guinea pigs.
Leiomyoma
Epstein-Barr virus-associated leiomyomatosis and posttransplant lymphoproliferative disorder in a child with severe combined immunodeficiency: case report and review of the literature.
Genetic variability within Adenosine Deaminase gene and uterine leiomyomas.
Leishmaniasis
Elevated Serum ADA Activity as a Marker for Diagnosis and Prognosis of Visceral Leishmaniasis and Post Kala-Azar Dermal Leishmaniasis in Indian Patients.
Leishmaniasis, Cutaneous
Adenosine deaminase activities in sera, lymphocytes and granulocytes in patients with cutaneous leishmaniasis.
Leishmaniasis, Visceral
Adenosine deaminase activity in sera of patients with visceral leishmaniasis in India.
Adenosine deaminase activity in sera of patients with visceral leishmaniasis in Nepal.
Conversion of asymptomatic infection to symptomatic visceral leishmaniasis: A study of possible immunological markers.
Elevated Serum ADA Activity as a Marker for Diagnosis and Prognosis of Visceral Leishmaniasis and Post Kala-Azar Dermal Leishmaniasis in Indian Patients.
Increased level of soluble adenosine deaminase in bone marrow of visceral leishmaniasis patients: an inverse relation with parasite load.
Serum nitrite level and adenosine deaminase activity is altered in visceral leishmaniasis.
Leprosy
Adenosine deaminase activity in leprosy (a preliminary study).
Adenosine deaminase activity in leprosy.
Adenosine deaminase activity in sera of patients with visceral leishmaniasis in India.
Lymphocyte adenosine deaminase activity (L-ADA) in leprosy, during and after treatment of reactions.
Serum adenosine deaminase levels in reactional and non-reactional leprosy.
The level of serum adenosine deaminase activity in leprosy and tuberculosis.
Leprosy, Multibacillary
Adenosine deaminase activity in serum and lymphocytes of multibacillary leprosy patients.
Lesch-Nyhan Syndrome
Disease-specific induced pluripotent stem cells.
Substrate inhibition of adenosine phosphorylation in adenosine deaminase deficiency and adenosine-mediated inhibition of PP-ribose-P dependent nucleotide synthesis in hypoxanthine phosphoribosyltransferase deficient erythrocytes.
Use of intact erythrocytes in the diagnosis of inherited purine and pyrimidine disorders.
Leukemia
2'-deoxycoformycin (DCF) and 9-beta-D-arabinofuranosyladenine (Ara-A) in the treatment of refractory acute myelocytic leukemia.
A comparison of some leucocyte differentiation markers and the adenosine deaminase and purine nucleoside phosphorylase values in B and T cell leukemias and lymphomas.
A novel therapeutic strategy against monocytic leukemia with deoxyadenosine analogs and adenosine deaminase inhibitors.
A single cycle of 2-chlorodeoxyadenosine results in complete remission in the majority of patients with hairy cell leukemia.
Adenosine analogs as possible differentiation-inducing agents against acute myeloid leukemia.
Adenosine deaminase (ADA) in leukemia: clinical value of plasma ADA activity and characterization of leukemic cell ADA.
Adenosine deaminase activity in lymphoid subpopulations and leukemias.
Adenosine deaminase activity in sera of patients with psoriasis, mycosis fungoides and adult T cell leukemia.
Adenosine deaminase activity in virus-induced murine leukemia.
Adenosine deaminase activity of normal lymphocytes and leukemic cells.
Adenosine deaminase and ecto-5'-nucleotidase activities in various leukemias with special reference to blast crisis: significance of ecto-5'-nucleotidase in lymphoid blast crisis of chronic myeloid leukemia.
Adenosine deaminase and purine nucleoside phosphorylase in acute and chronic lymphatic leukemia.
Adenosine deaminase and purine nucleoside phosphorylase levels in acute myeloblastic leukemia cells. Relationship to diagnosis and clinical course.
Adenosine deaminase in adult T cell leukemia.
Adenosine deaminase, terminal deoxynucleotidyl transferase (TdT), and cell surface markers in childhood acute leukemia.
Adenosine metabolism in plasma and platelets. IV. Elevated plasmatic adenosine deaminase activity, impaired platelet 14C-adenosine incorporation and hemostatic dysfunction in chronic myeloid leukemia.
Analysis by high-pressure liquid chromatography of 9-beta-D-arabinofuranosyladenine 5'-triphosphate levels in murine leukemia cells.
Antileukemic activity and mechanism of action of cordycepin against terminal deoxynucleotidyl transferase-positive (TdT+) leukemic cells.
Antiproliferative effects of 9-beta-D-arabinofuranosyladenine 5'-monophosphate and related compounds in combination with adenosine deaminase inhibitors against mouse leukemia L1210/C2 cells in culture.
Biochemical and biophysical approaches to improving the anticancer effectiveness of Ara-adenine.
Biochemical changes induced in hairy-cell leukemia following treatment with the adenosine deaminase inhibitor 2'-deoxycoformycin.
Biochemical consequences of adenosine deaminase inhibition in vivo. Differential effects in acute and chronic T cell leukemia.
Biochemical correlates of the differential sensitivity of subtypes of human leukemia to deoxyadenosine and deoxycoformycin.
Changes in the activities of cytidine deaminase during differentiation of HL60 cells induced by 1,25 dihydroxy D3.
Chemical stability of pentostatin (NSC-218321), a cytotoxic and immunosuppressant agent.
Cladribine. Ortho Biotech Inc.
Clinical relevance of terminal transferase and adenosine deaminase in leukemia.
Clinical significance of serum adenosine deaminase activity in patients with mycosis fungoides.
Clinical utility of terminal deoxynucleotidyl transferase and adenosine deaminase determinations in adult leukemia with a lymphoid phenotype.
Combined effects of interferon and 2'-deoxycoformycin on 2',5'-oligoadenylate synthetase and adenosine deaminase in hairy cell and chronic lymphocytic leukemia cells.
Conversion of a stem cell leukemia from a T-lymphoid to a myeloid phenotype induced by the adenosine deaminase inhibitor 2'-deoxycoformycin.
Current status of clinical trials of m-AMSA, dihydroxyanthracenedione, and deoxycoformycin.
Deoxycoformycin: an active new drug for indolent lymphomas and hairy cell leukemia.
Deoxyribonucleoside triphosphate accumulation by leukemic cells.
Detection of JC virus by anti-VP1 immunohistochemistry in brains with progressive multifocal leukoencephalopathy.
Development of a Simple Assay Method for Adenosine Deaminase via Enzymatic Formation of an Inosine-Tb3+ Complex.
Differential expression of adenosine deaminase isozymes in acute leukemia.
Differential sensitivity of leukemic cells to growth inhibition by deoxyadenosine and deoxycoformycin.
Dipyridamole enhancement of toxicity to L1210 cells by deoxyadenosine and deoxycoformycin combinations in vitro.
Durable complete remissions after 2'-deoxycoformycin treatment in patients with hairy cell leukemia resistant to interferon alpha.
Elevated erythrocyte adenosine deaminase activity in congenital hypoplastic anemia.
Enhancement of the antitumor activity of N6-(delta 2-isopentenyl)adenosine against cultured L-1210 leukemia cells by pentostatin using a polymeric delivery system.
Enhancement of the biological activity of adenosine analogs by the adenosine deaminase inhibitor 2'-deoxycoformycin.
Enzymatic differences between chronic lymphocytic leukemia and prolymphocytic leukemia.
Enzymes of the purine interconversion system in chronic lymphatic leukemia: decreased purine nucleoside phosphorylase and adenosine deaminase activity.
Establishment of the DU.528 human lymphohemopoietic stem cell line.
Genetic deficiencies of adenosine deaminase and purine nucleoside phosphorylase and their implications for therapy of leukemias.
Hairy cell leukemia: a successful model for experimental therapeutics--pentostatin and new ideas.
Hairy cell leukemia: results of 2-chlorodeoxyadenosine therapy in Jerusalem.
High adenosine deaminase level in the pleural effusion of a case with leukemia.
High-level expression from a cytomegalovirus promoter in macrophage cells.
Human monocytoid leukemia cells are highly sensitive to apoptosis induced by 2'-deoxycoformycin and 2'-deoxyadenosine: association with dATP-dependent activation of caspase-3.
Improved production of pentostatin and identification of fermentation cometabolites.
Increased cytotoxicity of N6-(delta 2-isopentenyl)adenosine in combination with pentostatin against L-1210 leukemia cells.
Induction of adenosine deaminase and 5' nucleotidase activity in cultured human blood monocytes and monocytic leukemia (THP-1) cells by differentiating agents.
Induction of apoptosis in vivo and in vitro in hairy cell leukemia treated by deoxycoformycin.
Leukemia inhibitory factor improves survival of retroviral vector-infected hematopoietic stem cells in vitro, allowing efficient long-term expression of vector-encoded human adenosine deaminase in vivo.
Leukocyte adenosine deaminase phenotypes in acute leukemia.
Long-term expression of human adenosine deaminase in mice after transplantation of bone marrow infected with amphotropic retroviral vectors.
Mechanism of adenosine triphosphate catabolism induced by deoxyadenosine and by nucleoside analogues in adenosine deaminase-inhibited human erythrocytes.
Molecular characterization as a target for cancer therapy in relation to orphan status disorders (Review).
Pentostatin and purine analogs for indolent lymphoid malignancies.
Pentostatin in the treatment of advanced hairy cell leukemia.
Pentostatin in the treatment of hairy-cell leukemia.
Pentostatin: an adenosine deaminase inhibitor for the treatment of hairy cell leukemia.
Phase II study of cladribine (2-chlorodeoxyadenosine) in relapsed or refractory adult T-cell leukemia-lymphoma.
PORPHOBILINOGEN DEAMINASE AND ADENOSINE DEAMINASE ACTIVITY AS A POSSIBLE DIAGNOSTIC AID IN LYMPHATIC LEUKEMIAS.
Possible pentostatin-induced symptomatic hyponatremia.
Purine metabolism enzymes and immunological phenotype in chronic B-cell malignancies: chronic lymphocytic leukemia, prolymphocytic leukemia and hairy cell leukemia.
Recovery of 2'-deoxycoformycin-inhibited adenosine deaminase of mouse erythrocytes and leukemia L1210 in vivo.
Relationship between adenosine deaminase and a human thymus leukemia antigen isolated from MOLT 4 cells.
Retroviral vectors encoding ADA regulatory locus control region provide enhanced T-cell-specific transgene expression.
Retrovirus-mediated gene transfer of human adenosine deaminase: expression of functional enzyme in murine hematopoietic stem cells in vivo.
Significance of enzyme markers as a part of multiple marker analysis in leukemia research.
Subchronic toxicity of pentostatin in Wistar rats.
Surface adenosine deaminase. A novel B-cell marker in chronic lymphocytic leukemia.
Synthesis and biological properties of 9-(trans-4-hydroxy-2-buten-1-yl)adenine and guanine: open-chain analogues of neplanocin A.
Therapeutic benefit of pentostatin in severe IL-10-/- colitis.
[Activity of adenosine deaminase in the blood serum of children. II. Activity of adenosine deaminase in leukemias in children.]
[Adenosine deaminase activity in blood cells; influence of cytostatic therapy in patients with acute leukemia and with renal transplants (author's transl)]
[Adenosine deaminase activity in blood plasma, erythrocytes and lymphocytes in leukemias]
[Adenosine deaminase activity in childhood acute leukemia]
[Adenosine deaminase activity in leukemia patients]
[Adenosine deaminase, purine nucleoside phosphorylase and ecto-5'-nucleotidase--markers of acute leukemia variants]
[Clinical significance of plasma adenosine deaminase (ADA) activity in leukemia]
[Combination assay of IAP and ADA in hematologic malignancies]
[Serum adenosine deaminase and its isozyme activity in leukemia and MDS]
Leukemia L1210
Comparison of the actions of 9-beta-D-arabinofuranosyl-2-fluoroadenine and 9-beta-D-arabinofuranosyladenine on target enzymes from mouse tumor cells.
Enhancement of 9-beta-d-arabinofuranosyladenine cytotoxicity to mouse leukemia L1210 in vitro by 2'-deoxycoformycin.
In vivo inhibition of adenosine deaminase by 2'-deoxycoformycin in mouse blood and leukemia L1210 cells.
Recovery of 2'-deoxycoformycin-inhibited adenosine deaminase of mouse erythrocytes and leukemia L1210 in vivo.
Synthesis and biological properties of 9-(trans-4-hydroxy-2-buten-1-yl)adenine and guanine: open-chain analogues of neplanocin A.
Leukemia, Feline
Purine metabolism in feline lymphomas.
Leukemia, Hairy Cell
A single cycle of 2-chlorodeoxyadenosine results in complete remission in the majority of patients with hairy cell leukemia.
Chemical stability of pentostatin (NSC-218321), a cytotoxic and immunosuppressant agent.
Combined effects of interferon and 2'-deoxycoformycin on 2',5'-oligoadenylate synthetase and adenosine deaminase in hairy cell and chronic lymphocytic leukemia cells.
Deoxycoformycin: an active new drug for indolent lymphomas and hairy cell leukemia.
Durable complete remissions after 2'-deoxycoformycin treatment in patients with hairy cell leukemia resistant to interferon alpha.
Hairy cell leukemia: results of 2-chlorodeoxyadenosine therapy in Jerusalem.
Improved production of pentostatin and identification of fermentation cometabolites.
Induction of apoptosis in vivo and in vitro in hairy cell leukemia treated by deoxycoformycin.
Pentostatin and purine analogs for indolent lymphoid malignancies.
Pentostatin in the treatment of advanced hairy cell leukemia.
Pentostatin: an adenosine deaminase inhibitor for the treatment of hairy cell leukemia.
Phase II study of cladribine (2-chlorodeoxyadenosine) in relapsed or refractory adult T-cell leukemia-lymphoma.
Possible pentostatin-induced symptomatic hyponatremia.
Purine metabolism enzymes and immunological phenotype in chronic B-cell malignancies: chronic lymphocytic leukemia, prolymphocytic leukemia and hairy cell leukemia.
Subchronic toxicity of pentostatin in Wistar rats.
Leukemia, Lymphocytic, Chronic, B-Cell
Adenosine and adenosine analogues are more toxic to chronic lymphocytic leukemia than to normal lymphocytes.
Adenosine Deaminase Activity in Chronic Lymphocytic Leukemia and Healthy Subjects.
Adenosine deaminase activity in chronic lymphocytic leukemia. Relationship to B- and T-cell subpopulations.
Adenosine deaminase activity in chronic lymphocytic leukemia: evaluation of lymphocytic ADA during and after treatment.
Cladribine. Ortho Biotech Inc.
Combined effects of interferon and 2'-deoxycoformycin on 2',5'-oligoadenylate synthetase and adenosine deaminase in hairy cell and chronic lymphocytic leukemia cells.
Deoxyribonucleoside triphosphate accumulation by leukemic cells.
Enzymatic differences between chronic lymphocytic leukemia and prolymphocytic leukemia.
Enzymological studies in chronic lymphocytic leukemia.
Induction of DNA strand breaks in chronic lymphocytic leukemia following treatment with 2'-deoxycoformycin in vivo and in vitro.
Intralymphocytic adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNPase) activity in chronic lymphocytic leukemia (CLL): effect of thymostimulin.
Patterns of adenosine deaminase, ecto-5'-nucleotidase, poly(A)polymerase and surface light chain expression in chronic lymphocytic leukemias.
Purine metabolism enzymes and immunological phenotype in chronic B-cell malignancies: chronic lymphocytic leukemia, prolymphocytic leukemia and hairy cell leukemia.
Purine nucleoside phosphorylase in chronic lymphocytic leukemia (CLL).
Surface adenosine deaminase. A novel B-cell marker in chronic lymphocytic leukemia.
Tumor lysis syndrome (TLS) following fludarabine therapy for chronic lymphocytic leukemia (CLL): case report and review of the literature.
[Enzymes of purine nucleotide catabolism in lymphocytes in normal states and in chronic lymphoid leukemia]
Leukemia, Lymphoid
Combined assay of adenosine deaminase, purine nucleoside phosphorylase, and lactate dehydrogenase in the early clinical evaluation of B-chronic lymphocytic leukemia.
Enhancement of the antitumor activity of N6-(delta 2-isopentenyl)adenosine against cultured L-1210 leukemia cells by pentostatin using a polymeric delivery system.
Enzymes of purine metabolism in B-chronic lymphocytic leukemia.
Surface adenosine deaminase. A novel B-cell marker in chronic lymphocytic leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
A biological marker model for predicting disease transitions.
Adenosine deaminase and ecto-5'-nucleotidase activities in various leukemias with special reference to blast crisis: significance of ecto-5'-nucleotidase in lymphoid blast crisis of chronic myeloid leukemia.
Adenosine deaminase and terminal deoxynucleotidyl transferase: biochemical markers in the management of chronic myelogenous leukemia.
Adenosine metabolism in plasma and platelets. IV. Elevated plasmatic adenosine deaminase activity, impaired platelet 14C-adenosine incorporation and hemostatic dysfunction in chronic myeloid leukemia.
Cladribine. Ortho Biotech Inc.
Differential expression of adenosine deaminase isozymes in acute leukemia.
Management of Gaucher disease in a post-communist transitional health care system: Croatian experience.
Molecular characterization as a target for cancer therapy in relation to orphan status disorders (Review).
Prognostic significance of terminal transferase and adenosine deaminase in acute and chronic myeloid leukemia.
[Certain biochemical features of leukocytes in blast crisis of chronic myelogenous leukemia]
[Combination assay of IAP and ADA in hematologic malignancies]
[Comparative characteristics of the catalytic properties of platelet adenosine deaminase in normal states and in chronic myeloid leukemia]
[Diagnosis and treatment of Gaucher disease in Croatia]
Leukemia, Myeloid
Adenosine metabolism in plasma and platelets. IV. Elevated plasmatic adenosine deaminase activity, impaired platelet 14C-adenosine incorporation and hemostatic dysfunction in chronic myeloid leukemia.
Leukemia, Myeloid, Acute
2'-deoxycoformycin (DCF) and 9-beta-D-arabinofuranosyladenine (Ara-A) in the treatment of refractory acute myelocytic leukemia.
Adenosine deaminase and purine nucleoside phosphorylase levels in acute myeloblastic leukemia cells. Relationship to diagnosis and clinical course.
Cladribine. Ortho Biotech Inc.
Deoxyribonucleoside triphosphate accumulation by leukemic cells.
Purine degradative enzymes and terminal transferase in acute myelogenous leukemia: clinical relevance.
[Combination assay of IAP and ADA in hematologic malignancies]
[Serum adenosine deaminase and its isozyme activity in leukemia and MDS]
Leukemia, Prolymphocytic
Enzymatic differences between chronic lymphocytic leukemia and prolymphocytic leukemia.
Induction of apoptosis in CD4+ prolymphocytic leukemia by deoxyadenosine and 2'-deoxycoformycin.
Purine metabolism enzymes and immunological phenotype in chronic B-cell malignancies: chronic lymphocytic leukemia, prolymphocytic leukemia and hairy cell leukemia.
Leukemia, T-Cell
Adenosine deaminase activity in lymphoid subpopulations and leukemias.
Adenosine deaminase activity in sera of patients with psoriasis, mycosis fungoides and adult T cell leukemia.
Adenosine deaminase in adult T cell leukemia.
Biochemical consequences of adenosine deaminase inhibition in vivo. Differential effects in acute and chronic T cell leukemia.
Clinical significance of serum adenosine deaminase activity in patients with mycosis fungoides.
Metabolism of adenosine and deoxyadenosine by human erythrocytes and CCRF-CEM leukemia cells.
[Combination assay of IAP and ADA in hematologic malignancies]
Leukemia-Lymphoma, Adult T-Cell
Adenosine deaminase in plasma of patients with adult T-cell leukemia (ATL): correlation between enzyme activity and the ATL subtypes.
Genetic analysis of adenosine deaminase expression in adult T-cell leukemia.
Leukocytosis
Longitudinal cerebrospinal fluid assessment in a patient with tuberculous meningitis-A case report.
Primary leptomeningeal lymphoma presenting as cerebellopontine angle lesion.
Primary peritonitis due to brucellosis mimicking tuberculous peritonitis.
[A case of listeria meningitis showed high levels of adenosine deaminase in cerebrospinal fluid]
Leukopenia
[Clinical characteristics of lung NK/T cell lymphoma misdiagnosed as pneumonia].
Liposarcoma
Adenosine deaminase activity in peripheral lymphocytes of patients with gynaecologic malignancies.
Livedo Reticularis
A homozygote novel L451W mutation in CECR1 gene causes deficiency of adenosine deaminase 2 in a pediatric patient representing with chronic lymphoproliferation and cytopenia.
Renal Amyloidosis in Deficiency of Adenosine Deaminase 2: Successful Experience With Canakinumab.
Liver Abscess, Amebic
Decreased adenosine deaminase activity in peripheral lymphocytes of patients suffering from amebic liver abscess.
Liver Cirrhosis
Adenosine deaminase activity in tuberculous peritonitis among patients with underlying liver cirrhosis.
Adenosine deaminase isoenzymes and neopterin in liver cirrhosis.
Serum Activity of Macrophage-Derived Adenosine Deaminase 2 Is Associated With Liver Fibrosis in Nonalcoholic Fatty Liver Disease.
[Clinical significance of cytokine measurement in pleural effusion]
[Correlation between serum adenosine deaminase, peripheral T lymphocyte subsets and syndrome types of traditional Chinese medicine in liver-cirrhosis patients]
[Determination of serum adenosine deaminase: its diagnostic value in jaundice and liver fibrosis]
[Enzymatic activity of serum adenosine deaminase in different liver disorders]
[Value of adenosine deaminase as indicator of tuberculosis in ascites fluid in a case of liver cirrhosis]
Liver Cirrhosis, Alcoholic
Blunted anti-inflammatory response to adenosine in alcoholic cirrhosis.
Diagnostic value of ascites adenosine deaminase in tuberculous peritonitis.
Liver Diseases
Adenosine deaminase activity in liver diseases.
Adenosine deaminase in the serum of patients with liver diseases.
Adenosine deaminase isoenzymes in liver disease.
Diagnostic value of adenosine deaminase in some liver diseases.
Different levels of lymphocyte adenosine deaminase in active and inactive forms of chronic liver disease.
Lymphocyte adenosine deaminase levels in active and in inactive forms of HBsAg-positive chronic liver disease.
Observations on serum adenosine deaminase activity in experimentally produced liver diseases of cattle and sheep: yellow-wood, lantana, carbon tetrachloride and chronic copper poisoning.
Polyethylene glycol-modified adenosine deaminase improved lung disease but not liver disease in partial adenosine deaminase deficiency.
Serum Activity of Macrophage-Derived Adenosine Deaminase 2 Is Associated With Liver Fibrosis in Nonalcoholic Fatty Liver Disease.
Serum adenosine deaminase activity in bovine liver diseases.
Serum adenosine deaminase, 5' nucleotidase and malondialdehyde in acute infective hepatitis.
[Adenosine deaminase activity--an indicator of inflammation in liver disease]
[Clinical characteristics of lung NK/T cell lymphoma misdiagnosed as pneumonia].
[Clinical significance of measurement of serum adenosine deaminase activity in patients with various liver diseases]
[Enzymatic activity of serum adenosine deaminase in different liver disorders]
[Serum adenosine deaminase in acute viral hepatitis and chronic liver diseases]
Liver Failure
Activation of AMP deaminase and adenosine deaminase in the liver during ammonia poisoning and hepatitis.
Hyperbilirubinemia and Rapid Fatal Hepatic Failure in Severe Combined Immunodeficiency Caused by Adenosine Deaminase Deficiency (ADA-SCID).
Lung Diseases
Adenosine deaminase 1 and concentrative nucleoside transporters 2 and 3 regulate adenosine on the apical surface of human airway epithelia: implications for inflammatory lung diseases.
Adenosine deaminase in the modulation of immune system and its potential as a novel target for treatment of inflammatory disorders.
Enhanced airway inflammation and remodeling in adenosine deaminase-deficient mice lacking the A2B adenosine receptor.
Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice.
Non-infectious Lung Disease in Patients with Adenosine Deaminase Deficient Severe Combined Immunodeficiency.
Polyethylene glycol-modified adenosine deaminase improved lung disease but not liver disease in partial adenosine deaminase deficiency.
[Changes in adenosine deaminase and antioxidative enzyme activity in patients with lung diseases of dust etiology]
Lung Injury
Endothelial cell-specific deficiency of the adenosine deaminase ADAR1 aggravates LPS-induced lung injury in mice via an MDA5-independent pathway.
Role of pulmonary adenosine during hypoxia: extracellular generation, signaling and metabolism by surface adenosine deaminase/CD26.
Lung Neoplasms
A novel diagnostic method for distinguishing parapneumonic effusion and empyema from other diseases by using the pleural lactate dehydrogenase to adenosine deaminase ratio and carcinoembryonic antigen levels.
Adenosine deaminase and purine nucleoside phosphorylase activities in lymphocytes from patients with lung cancer.
Adenosine deaminase isozymes in tuberculous pleural effusion.
Changes in lymphocyte adenosine deaminase and purine nucleoside phosphorylase levels in lung cancer after radical surgery.
Effect of TEI-6720, a xanthine oxidase inhibitor, on the nucleoside transport in the lung cancer cell line A549.
Gene transfer and antisense nucleic acid techniques.
Is adenosine deaminase in pleural fluid a useful marker for differentiating tuberculosis from lung cancer or mesothelioma in Japan, a country with intermediate incidence of tuberculosis?
Lung cancer alters the hydrolysis of nucleotides and nucleosides in platelets.
Multienzyme patterns of serum adenosine deaminase by agar gel electrophoresis: an evaluation of the diagnostic value in lung cancer.
RNA editing of AZIN1 induces the malignant progression of non-small-cell lung cancers.
Serum adenosine deaminase activities in lung cancer and mesothelioma.
The case for performing pleural biopsies for the aetiological diagnosis of exudates. Yes.
The diagnostic value of adenosine deaminase activity in sputum in pulmonary tuberculosis.
The effects of quercetin on antioxidant status and tumor markers in the lung and serum of mice treated with benzo(a)pyrene.
Transthyretin as a potential biomarker for the differential diagnosis between lung cancer and lung infection.
Tumor markers in pleural effusion diagnosis.
Lupus Erythematosus, Systemic
A clinical score to guide in decision making for monogenic type I IFNopathies.
Adenosine deaminase activity and its isoenzyme pattern in patients with juvenile rheumatoid arthritis and systemic lupus erythematosus.
Altered editing in RNA editing adenosine deaminase ADAR2 gene transcripts of systemic lupus erythematosus T lymphocytes.
Elevated signal transducers and activators of transcription 1 correlates with increased C-C motif chemokine ligand 2 and C-X-C motif chemokine 10 levels in peripheral blood of patients with systemic lupus erythematosus.
Induction of 150-kDa adenosine deaminase that acts on RNA (ADAR)-1 gene expression in normal T lymphocytes by anti-CD3-epsilon and anti-CD28.
Pleural fluid adenosine deaminase in rheumatoid arthritis and systemic lupus erythematosus.
Potential role of adenosine deaminase in the diagnosis of adult-onset Still's disease.
Reduced levels of CCL2 and CXCL10 in systemic lupus erythematosus patients under treatment with prednisone, mycophenolate mofetil, or hydroxychloroquine, except in a high STAT1 subset.
Serum adenosine deaminase activity and its isoenzyme pattern in patients with systemic lupus erythematosus.
Serum adenosine deaminase activity in patients with systemic lupus erythematosus: a study based on ADA1 and ADA2 isoenzymes pattern.
Serum adenosine deaminase activity is increased in systemic lupus erythematosus patients and correlated with disease activity.
Serum adenosine deaminase and cytidine deaminase activities in patients with systemic lupus erythematosus.
Lymphadenopathy
Development of a clinical prediction rule for the diagnosis of pleural tuberculosis in Peru.
[Adenosine deaminase in differential diagnosis of peripheral lymph node tuberculosis]
Lymphocytosis
[A case of tuberculous meningitis with pleural effusion as a manifestation of a paradoxical reaction during anti-tuberculosis therapy].
[A case of tuberculous pleurisy distinguished from pleurisy caused by Mycoplasma infection].
Lymphohistiocytosis, Hemophagocytic
Elevated serum adenosine deaminase levels in secondary hemophagocytic lymphohistiocytosis.
[The clinical significance of serum neopterin and adenosine deaminase in patients with secondary hemophagocytic lymphohistiocytosis].
Lymphoma
A comparison of some leucocyte differentiation markers and the adenosine deaminase and purine nucleoside phosphorylase values in B and T cell leukemias and lymphomas.
A novel diagnostic method for distinguishing parapneumonic effusion and empyema from other diseases by using the pleural lactate dehydrogenase to adenosine deaminase ratio and carcinoembryonic antigen levels.
A novel therapeutic strategy against monocytic leukemia with deoxyadenosine analogs and adenosine deaminase inhibitors.
A role for sialoadhesin-positive tissue macrophages in host resistance to lymphoma metastasis in vivo.
Adenosine deaminase activity in pleural effusions of lymphoma patients.
Adenosine deaminase and terminal deoxynucleotidyl transferase in human lymphomas: an aid to the diagnosis and subclassification of lymphoblastic lymphomas.
Adenosine deaminase concentrations in leukaemia and lymphoma: relation to cell phenotypes.
Adenosine deaminase positive, E receptor negative lymphoma.
CD26, together with cell surface adenosine deaminase, is selectively expressed on ALK-positive, but not on ALK-negative, anaplastic large cell lymphoma and Hodgkin's lymphoma.
CD26/dipeptidyl peptidase IV expression in human lymphomas is restricted to CD30-positive anaplastic large cell and a subset of T-cell non-Hodgkin's lymphomas.
Cerebral lymphoma in an adenosine deaminase-deficient patient with severe combined immunodeficiency receiving polyethylene glycol-conjugated adenosine deaminase.
Clinical resistance to antimetabolites.
Concurrent small bowel lymphoma and mycobacterial infection: use of adenosine deaminase activity and polymerase chain reaction to facilitate rapid diagnosis and treatment.
Diagnostic value of cerebrospinal fluid adenosine deaminase determination.
Hematopoietic stem cell gene therapy with drug resistance genes: an update.
Human monocytoid leukemia cells are highly sensitive to apoptosis induced by 2'-deoxycoformycin and 2'-deoxyadenosine: association with dATP-dependent activation of caspase-3.
Immunohistochemical localization of adenosine deaminase in human lymphoid tissues and lymphomas.
In-situ activated macrophages are involved in host-resistance to lymphoma metastasis by production of nitric-oxide.
Isolation and characterization of S49 mouse lymphoma cell mutants deficient in adenosine deaminase.
Lymphoma in a patient with severe combined immunodeficiency with adenosine deaminase deficiency, following unsustained engraftment of histoincompatible T cell-depleted bone marrow.
Misdiagnosis of primary pleural DLBCL as tuberculosis: A case report and literature review.
Modulation of adenine nucleoside excretion and incorporation in adenosine deaminase deficient human lymphoma cells.
Pentostatin and purine analogs for indolent lymphoid malignancies.
Phase II study of cladribine (2-chlorodeoxyadenosine) in relapsed or refractory adult T-cell leukemia-lymphoma.
Pleural Fluid Adenosine Deaminase (ADA) Predicts Survival in Patients with Malignant Pleural Effusion.
Relation between enzymatic activities and the degree of malignancy of human lymphomas.
Simultaneous assay of adenosine deaminase and purine nucleoside phosphorylase activity as possible biochemical means to detect non-Hodgkin lymphomas of the oral cavity.
Treatment of cutaneous T cell lymphoma with 2'-deoxycoformycin (pentostatin).
[A case of natural killer cell lymphoma with high adenosine deaminase level in pleural effusion]
[Clinical characteristics of lung NK/T cell lymphoma misdiagnosed as pneumonia].
[Combination assay of IAP and ADA in hematologic malignancies]
Lymphoma, B-Cell
Immunohistochemical localization of adenosine deaminase in human benign extrathymic lymphoid tissues and B-cell lymphomas.
Lymphoma, Follicular
[Treatment of recurrent lymphoma]
Lymphoma, Large B-Cell, Diffuse
Deoxynucleoside overproduction in deoxyadenosine-resistant, adenosine deaminase-deficient human histiocytic lymphoma cells.
Increased level of ribonucleotide reductase in deoxyadenosine resistant adenosine deaminase deficient human histiocytic lymphoma cells.
Lymphoma, Large-Cell, Anaplastic
CD26, together with cell surface adenosine deaminase, is selectively expressed on ALK-positive, but not on ALK-negative, anaplastic large cell lymphoma and Hodgkin's lymphoma.
Lymphoma, Non-Hodgkin
Adenosine deaminase activity in pleural effusions of lymphoma patients.
Cladribine. Ortho Biotech Inc.
Elevated Adenosine Deaminase in Pleural Effusion A Case of Non-Hodgkin Lymphoma Misdiagnosis.
Non-Hodgkin lymphoma with high adenosine deaminase levels mimicking peritoneal tuberculosis: An unusual presentation.
Pyrimidine and purine activities in non-Hodgkin's lymphoma. Correlation with histological status and survival.
Lymphoma, T-Cell
2-Chlorodeoxyadenosine: an active agent in the treatment of cutaneous T-cell lymphoma.
Analysis of adenosine-mediated pyrimidine starvation using cultured wild-type and mutant mouse T-lymphoma cells.
CD26 in T-cell lymphomas: a potential clinical role?
CD26, together with cell surface adenosine deaminase, is selectively expressed on ALK-positive, but not on ALK-negative, anaplastic large cell lymphoma and Hodgkin's lymphoma.
Cladribine. Ortho Biotech Inc.
Possible pentostatin-induced symptomatic hyponatremia.
Transient stimulatory adenosine deaminase activity in peripheral lymphocyte lysates from a case of T-cell lymphoma.
Lymphoma, T-Cell, Cutaneous
Phase II study of cladribine (2-chlorodeoxyadenosine) in relapsed or refractory adult T-cell leukemia-lymphoma.
Treatment of cutaneous T cell lymphoma with 2'-deoxycoformycin (pentostatin).
Lymphopenia
Adenosine deaminase deficiency with normal immune function. An acidic enzyme mutation.
Adenosine deaminase deficiency: genotype-phenotype correlations based on expressed activity of 29 mutant alleles.
Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation.
Adenosine deaminase messenger RNAs in lymphoblast cell lines derived from leukemic patients and patients with hereditary adenosine deaminase deficiency.
Advances in basic and clinical immunology in 2011.
Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs toward malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo.
Function of murine adenosine deaminase in the gastrointestinal tract.
Heterozygous Mutation in Adenosine Deaminase Gene in a Patient With Severe Lymphopenia Following Corticosteroid Treatment of Autoimmune Hemolytic Anemia.
Inhibition of DNA repair by deoxyadenosine in resting human lymphocytes.
Inhibition of RNA synthesis by deoxyadenosine plus deoxycoformycin in resting lymphocytes.
Lymphocyte dysfunction caused by deficiencies in purine metabolism.
Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes.
Myeloid dysplasia and bone marrow hypocellularity in adenosine deaminase-deficient severe combined immune deficiency.
Novel ADA2 mutation presenting with neutropenia, lymphopenia and bone marrow failure in patients with deficiency in adenosine deaminase 2 (DADA2).
Purine analogs in chronic lymphocytic leukemia and Waldenström's macroglobulinemia.
Resistance of an adenosine kinase-deficient human lymphoblastoid cell line to effects of deoxyadenosine on growth, S-adenosylhomocysteine hydrolase inactivation, and dATP accumulation.
The importance of adenosine deaminase for lymphocyte development and function.
[Adenosine deaminase 1 deficiency, an inborn error of metabolism underlying a severe form of combined immunodeficiency].
Lymphoproliferative Disorders
A new mixed inhibitor of adenosine deaminase produced by endophytic Cochliobolus sp. from medicinal plant seeds.
Immunological and genetic abnormalities in chronic lymphocytic leukaemia. Impact of the purine analogues.
Pentostatin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in lymphoproliferative disorders.
Purine nucleoside phosphorylase (PNP) and adenosine deaminase (ADA) activities examined cytochemically in unfixed lymphocytes of patients with lymphoproliferative disorders.
Reynoutria Japonica from Traditional Chinese Medicine: A Source of Competitive Adenosine Deaminase Inhibitors for Anticancer.
Macrophage Activation Syndrome
Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis.
Old Dogs, New Tricks: Monogenic Autoinflammatory Disease Unleashed.
Malaria
Adenosine deaminase activity in sera of patients with visceral leishmaniasis in India.
Adenosine deaminase in malaria infected erythrocytes: unique parasite enzyme presents a new therapeutic target.
Adenosine deaminase in malaria infection: effect of 2'-deoxycoformycin in vivo.
Host resistance to murine malaria in mice exposed to the adenosine deaminase inhibitor, 2'-deoxycoformycin.
Human malaria parasite adenosine deaminase. Characterization in host enzyme-deficient erythrocyte culture.
L-purine nucleosides as selective antimalarials.
Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity.
Studies on biochemical changes with special reference to oxidant and antioxidants in malaria patients.
The deamination of adenosine and adenosine monophosphate in Plasmodium falciparum-infected human erythrocytes: in vitro use of 2'deoxycoformycin and AMP deaminase-deficient red cells.
[Adenosine deaminase and nucleoside phosphorylase in malaria parasites]
Malaria, Cerebral
Characteristic abnormalities in cerebrospinal fluid biochemistry in children with cerebral malaria compared to viral encephalitis.
Malaria, Vivax
Serum erythrocyte and leukocyte adenosine deaminase activities in patients with vivax malaria in Turkey.
Malnutrition
Effect of undernutrition on some enzymes of purine metabolism in different regions of developing rat brain.
Maple Syrup Urine Disease
Evaluation of the expanded newborn screening program in New York City.
Measles
Double-stranded RNA adenosine deaminase activity during measles virus infection.
Measles Virus Defective Interfering RNAs Are Generated Frequently and Early in the Absence of C Protein and Can Be Destabilized by Adenosine Deaminase Acting on RNA-1-Like Hypermutations.
RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis.
RNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKR.
Stress granule formation induced by measles virus is protein kinase PKR dependent and impaired by RNA adenosine deaminase ADAR1.
Melanoma
1?, 25-Dihydroxyvitamin D3 alters ectonucleotidase expression and activity in human cutaneous melanoma cells.
A novel diagnostic method for distinguishing parapneumonic effusion and empyema from other diseases by using the pleural lactate dehydrogenase to adenosine deaminase ratio and carcinoembryonic antigen levels.
Adenosine deaminase activity in lymphocyte subpopulations of B-16 melanoma and normal C57BL bearing mice.
Cell surface antigens of human melanocytes and melanoma. Expression of adenosine deaminase binding protein is extinguished with melanocyte transformation.
Characterization of adenosine-induced cytostasis in melanoma cells.
Gene therapy: here to stay.
Gene transfer and antisense nucleic acid techniques.
High-sensitivity capillary electrophoresis method for monitoring purine nucleoside phosphorylase and adenosine deaminase reactions by a reversed electrode polarity switching mode.
Nucleotide-metabolism and chromosome alterations in human-malignant melanoma xenografts.
Reinforcement of antitumor effect of Cordyceps sinensis by 2'-deoxycoformycin, an adenosine deaminase inhibitor.
Safety and efficacy of suicide gene therapy with adenosine deaminase 5-fluorocytosine silmutaneously in in vitro cultures of melanoma and retinal cell lines.
The p150 Isoform of ADAR1 Blocks Sustained RLR signaling and Apoptosis during Influenza Virus Infection.
[Gene transfer and gene therapy]
Meningeal Carcinomatosis
Cerebrospinal fluid adenosine deaminase activity for the diagnosis of tuberculous meningitis in adults.
Meningitis
A Hospital Based Study on Estimation of Adenosine Deaminase Activity (ADA) in Cerebrospinal Fluid (CSF) in Various Types of Meningitis.
Activity of adenosine deaminase in cerebrospinal fluid for the diagnosis and follow-up of tuberculous meningitis in adults.
Adenosine deaminase activity in cerebrospinal fluid and serum for the diagnosis of tuberculous meningitis.
Adenosine deaminase activity in the CSF of patients with aseptic meningitis: utility in the diagnosis of tuberculous meningitis or neurobrucellosis.
Adenosine deaminase and C-reactive protein in cerebrospinal fluid for differential diagnosis of tubercular meningitis in children.
Adenosine deaminase concentration in cerebrospinal fluid during brucella meningitis.
Adenosine deaminase in cerebrospinal fluid during brucella meningitis.
Adenosine deaminase levels in cerebrospinal fluid as a diagnostic test for tuberculous meningitis in children.
Aseptic meningitis in Kikuchi's disease mimicking tuberculous meningitis.
Cerebrospinal fluid adenosine deaminase activity for the diagnosis of tuberculous meningitis in adults.
Cerebrospinal fluid C reactive protein and adenosine deaminase in meningitis in adults.
Comparative analysis of cerebrospinal fluid adenosine deaminase activity in meningitis.
Comparative analysis of cerebrospinal fluid adenosine deaminase in tuberculous and non-tuberculous meningitis.
Comparative study of cerebrospinal fluid adenosine deaminase activity in patients with meningitis.
Determination of cerebrospinal fluid adenosine deaminase activity cut-off for the diagnosis of tuberculous meningitis in Hong Kong.
Elevated cerebrospinal fluid adenosine deaminase levels in patients with meningitis caused by varicella-zoster virus.
Elevation of CSF adenosine deaminase in HIV patient with meningitis from retroviral rebound syndrome, a case report.
Evaluation of Cerebrospinal Fluid Adenosine Deaminase Activity for the Differential Diagnosis of Tuberculous and Nontuberculous Meningitis.
Molecular forms of adenosine deaminase do not aid the diagnosis of tuberculosis.
Sarcoid meningitis, high adenosine deaminase levels in CSF and results of cranial irradiation.
Significance of cerebrospinal fluid adenosine deaminase isoenzymes in tuberculous (TB) meningitis.
The possible role of cerebrospinal fluid adenosine deaminase activity in the diagnosis of tuberculous meningitis in adults.
The value of CSF adenosine deaminase levels in the differential diagnosis of childhood meningitis.
[Adenosine deaminase in the complex diagnosis of different forms of extrapulmonary tuberculosis]
[Adenosine deaminase. False negatives in tuberculous meningitis]
[Diagnosis of tuberculosis meningitis by detection of adenosine deaminase activity and amplification of nucleotide sequences with PCR]
[Meningitis caused by Listeria monocytogenes with high levels of adenosine deaminase.]
[The activities of 3 enzymes in serum and cerebrospinal fluid for diagnosis of tuberculous meningitis]
Meningitis, Aseptic
Adenosine deaminase activity in the CSF of patients with aseptic meningitis: utility in the diagnosis of tuberculous meningitis or neurobrucellosis.
Adenosine deaminase and C-reactive protein in cerebrospinal fluid for differential diagnosis of tubercular meningitis in children.
Adenosine deaminase levels in cerebrospinal fluid as a diagnostic test for tuberculous meningitis in children.
Adenosine deaminase levels in cerebrospinal fluid in the diagnosis of tuberculous meningitis.
Cerebrospinal fluid adenosine deaminase activity for the diagnosis of tuberculous meningitis in adults.
High levels of adenosine deaminase in patients with aseptic meningitis.
[Aseptic meningitis with elevated adenosine deaminase (ADA) after interruption of antiretroviral treatment.]
Meningitis, Bacterial
Adenosine deaminase levels in cerebrospinal fluid in the diagnosis of tuberculous meningitis.
Adenosine deaminase levels in cerebrospinal fluid in tuberculosis and bacterial meningitis.
Cerebrospinal fluid adenosine deaminase activity and C-reactive protein in tuberculous and partially treated bacterial meningitis.
Cerebrospinal fluid adenosine deaminase activity for the diagnosis of tuberculous meningitis in adults.
Cerebrospinal fluid adenosine deaminase activity for the diagnosis of tuberculous meningitis in children.
Diagnostic value of cerebrospinal fluid adenosine deaminase determination.
Prognostic significance of cerebrospinal fluid adenosine deaminase in acute bacterial meningitis.
Revival of old diagnostic markers in the cerebrospinal fluid for the detection of infectious meningitis.
The value of CSF adenosine deaminase levels in the differential diagnosis of childhood meningitis.
Meningitis, Cryptococcal
Cerebrospinal fluid adenosine deaminase activity for the diagnosis of tuberculous meningitis in adults.
Cerebrospinal fluid adenosine deaminase levels in a patient with cryptococcal meningitis.
Cryptococcal meningitis associated with increased adenosine deaminase in the cerebrospinal fluid.
[Cryptococcal meningitis in patients with AIDS: combined treatment with amphotericin B and fluconazole, and high levels of adenosine deaminase in cerebrospinal fluid]
Meningitis, Listeria
A case of Listeria meningitis associated with increased adenosine deaminase in cerebrospinal fluid.
[A case of listeria meningitis showed high levels of adenosine deaminase in cerebrospinal fluid]
Meningitis, Viral
Diagnostic value of cerebrospinal fluid adenosine deaminase determination.
Meningoencephalitis
A case of hypogammaglobulinemia with enteroviral meningoencephalitis, associated with increased adenosine deaminase in cerebrospinal fluid.
Pearls & Oy-sters: chronic mumps meningoencephalitis with low CSF glucose and acute hydrocephalus in an adult.
The value of CSF adenosine deaminase levels in the differential diagnosis of childhood meningitis.
Mesothelioma
A continuous method for the estimation of adenosine deaminase catalytic concentration in pleural effusions with a Hitachi 705 discrete analyser.
A novel diagnostic method for distinguishing parapneumonic effusion and empyema from other diseases by using the pleural lactate dehydrogenase to adenosine deaminase ratio and carcinoembryonic antigen levels.
Adenosine Deaminase in Pleural Effusion and Its Relationship with Clinical Parameters in Patients with Malignant Pleural Mesothelioma.
Adenosine deaminase inhibitor EHNA exhibits a potent anticancer effect against malignant pleural mesothelioma.
Is adenosine deaminase in pleural fluid a useful marker for differentiating tuberculosis from lung cancer or mesothelioma in Japan, a country with intermediate incidence of tuberculosis?
Role of biochemical tests in the diagnosis of exudative pleural effusions.
Serum adenosine deaminase activities in lung cancer and mesothelioma.
The case for performing pleural biopsies for the aetiological diagnosis of exudates. Yes.
[Adenosine deaminase and mesothelioma]
[Mesothelioma and pleural adenosine deaminase]
Metabolic Diseases
Determination of adenosine deaminase activity in dried blood spots by a nonradiochemical assay using reversed-phase high-performance liquid chromatography.
Patients with adenosine deaminase deficiency surviving after hematopoietic stem cell transplantation are at high risk of CNS complications.
Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency.
Metabolic Syndrome
Contributory role of adenosine deaminase in metabolic syndrome.
Mevalonate Kinase Deficiency
Autoinflammatory diseases in childhood, part 1: monogenic syndromes.
Diagnostic utility of a targeted next-generation sequencing gene panel in the clinical suspicion of systemic autoinflammatory diseases: a multi-center study.
Growth Parameters of Turkish Children With an Autoinflammatory Disease Before and After Canakinumab Treatment.
Migraine Disorders
Case-control study of ADARB1 and ADARB2 gene variants in migraine.
Mucolipidoses
Electrophoretic analysis of glycoprotein enzymes in the sialidoses and mucolipidoses.
Multiple Myeloma
Pleural effusion in multiple myeloma.
[Combination assay of IAP and ADA in hematologic malignancies]
Multiple Sclerosis
Activity of adenosine deaminase in red blood cells of patients suffering from multiple sclerosis treated with adrenocorticotropic hormone.
Adenosine deaminase and 5'nucleotidase activities in peripheral blood T cells of multiple sclerosis patients.
Alterations in the cholinesterase and adenosine deaminase activities and inflammation biomarker levels in patients with multiple sclerosis.
Management of Gaucher disease in a post-communist transitional health care system: Croatian experience.
Multiple sclerosis showing elevation of adenosine deaminase levels in the cerebrospinal fluid.
Red blood cell adenosine deaminase activity in multiple sclerosis.
[Diagnosis and treatment of Gaucher disease in Croatia]
Mumps
Sensorineural deafness in siblings with adenosine deaminase deficiency.
The value of CSF adenosine deaminase levels in the differential diagnosis of childhood meningitis.
Muscular Dystrophies
Towards gene therapy for the central nervous system.
Muscular Dystrophy, Duchenne
Disease-specific induced pluripotent stem cells.
Gene therapy in man and mice: adenosine deaminase deficiency, ornithine transcarbamylase deficiency, and Duchenne muscular dystrophy.
Increased Number of Circulating CD8/CD26 T Cells in the Blood of Duchenne Muscular Dystrophy Patients Is Associated with Augmented Binding of Adenosine Deaminase and Higher Muscular Strength Scores.
Myasthenia Gravis
A molecular hypothesis concerning the pathogenesis of myasthenia gravis.
High serum adenosine deaminase activity and its correlation with lymphocyte subsets in myasthenia gravis.
Isozyme analysis of the high serum adenosine deaminase activity in patients with myasthenia gravis.
Mycoses
A prospective study of magnetic resonance imaging patterns of central nervous system infections in pediatric age group and young adults and their clinico-biochemical correlation.
Mycosis Fungoides
Adenosine deaminase activity in sera of patients with psoriasis, mycosis fungoides and adult T cell leukemia.
An investigation of 2'-deoxycoformycin in the treatment of cutaneous T-cell lymphoma.
Clinical significance of serum adenosine deaminase activity in patients with mycosis fungoides.
Normal serum adenosine deaminase activity in mycosis fungoides.
Myelitis
Tuberculous myelitis diagnosed by elevated adenosine deaminase activity in cerebrospinal fluid.
Myelodysplastic Syndromes
Biologic relevance of elevated red cell adenosine deaminase activity in myelodysplastic syndromes and paroxysmal nocturnal hemoglobinuria.
Elevated red cell adenosine deaminase and haemolysis in a patient with a myelodysplastic syndrome.
[Combination assay of IAP and ADA in hematologic malignancies]
Myeloproliferative Disorders
[Adenosine deaminase (ADA), 5'-nucleotidase (5'N) and purine nucleoside phosphorylase (PNP) in lympho- and myeloproliferative disorders]
Myocardial Infarction
Adenosine deaminase in ischemia reperfusion injury in patients with myocardial infarction.
Adenosine deaminase inhibition augments interstitial adenosine but does not attenuate myocardial infarction.
AMP deaminase, 5'-nucleotidase and adenosine deaminase in rat myocardial tissue in myocardial infarction and hypothermia.
Effect of temperature on myocardial infarction in swine.
Effects of ischemia, preconditioning, and adenosine deaminase inhibition on interstitial adenosine levels and infarct size.
Erythrocyte adenosine deaminase as a marker of reperfusion injury in patients with myocardial infarction.
Erythrocytic adenosine deaminase in post myocardial infarction angina patients.
Evaluation of the roles of adenosine deaminase and xanthine oxidase in reperfusion injury in patients with myocardial infarction.
[The involvement of adenosine and adenosine deaminase in experimental myocardial infarct]
Myocardial Ischemia
Effect of adenosine deaminase inhibition with pentostatin on myocardial stunning in dogs.
Myocardial Stunning
Augmentation of endogenous adenosine attenuates myocardial 'stunning' independently of coronary flow or hemodynamic effects.
Differential cardioprotection with selective inhibitors of adenosine metabolism and transport: role of purine release in ischemic and reperfusion injury.
Effect of adenosine deaminase inhibition with pentostatin on myocardial stunning in dogs.
Enhanced interstitial fluid adenosine attenuates myocardial stunning.
Hot shot induction and reperfusion with a specific blocker of the es-ENT1 nucleoside transporter before and after hypothermic cardioplegia abolishes myocardial stunning in acutely ischemic hearts despite metabolic derangement: Hot shot drug delivery before hypothermic cardioplegia.
Protective effects of adenosine in the reversibly injured heart.
Role of adenosine for reactive hyperemia in normal and stunned porcine myocardium.
Role of nucleoside transport and purine release in a rabbit model of myocardial stunning.
Myxedema
Probable autoimmune thyroid disease and combined immunodeficiency disease.
Nasal Polyps
Malondialdehyde level and adenosine deaminase activity in nasal polyps.
Neoplasm Metastasis
A novel diagnostic method for distinguishing parapneumonic effusion and empyema from other diseases by using the pleural lactate dehydrogenase to adenosine deaminase ratio and carcinoembryonic antigen levels.
A role for sialoadhesin-positive tissue macrophages in host resistance to lymphoma metastasis in vivo.
Decreased adenosine deaminase activity in peripheral lymphocytes from tumor patients with metastasis.
Ectonucleotide pyrophosphatase/phosphodiesterase (E-NPP) and adenosine deaminase (ADA) activities in prostate cancer patients: Influence of Gleason score, treatment and bone metastasis.
In-situ activated macrophages are involved in host-resistance to lymphoma metastasis by production of nitric-oxide.
Normal Tumor Markers and Increased Adenosine Deaminase in Pericardial Effusion Misdiagnosed as Tuberculous Pericarditis Ultimately Proven as Lung Adenocarcinoma with Pericardial Metastasis: a Case Report and Literature Review.
[Adenosine metabolism in lymphocytes and neurochemical stressor reactions in mice with metastatic Lewis carcinoma after surgical removal of the tumor]
[Enzymes of adenosine metabolism in lymphocytes and the functional state of the sympatho-adrenal system in tumor processes]
[The effect of Leu- and Met-enkephalins on the adenosine deaminase and 5'-nucleotidase activities of the lymphocytes under conditions of stress stimulation of metastasis]
Neoplasms
2-Chlorodeoxyadenosine: an active agent in the treatment of cutaneous T-cell lymphoma.
A Case of Askin's Tumor Presenting with Pleural Effusion and High Level of Adenosine Deaminase.
A case of tuberculous peritonitis in a hemodialysis patient with high serum soluble interleukin-2 receptor and CA-125 levels.
A fatal case of tuberculous meningitis in a child with juvenile idiopathic arthritis: a diagnostic challenge.
A new mixed inhibitor of adenosine deaminase produced by endophytic Cochliobolus sp. from medicinal plant seeds.
A phase I trial of alpha-interferon in combination with pentostatin in hematologic malignancies.
A role for sialoadhesin-positive tissue macrophages in host resistance to lymphoma metastasis in vivo.
Action of deoxycoformycin on human T cell colonies in vitro.
Activity of adenosine deaminase in cerebrospinal fluid for the diagnosis and follow-up of tuberculous meningitis in adults.
Activity of pentostatin (Nipent) in cutaneous T-cell lymphoma: single-agent and combination studies.
Acute effect of ?-sitosterol on calcium uptake mediates anti-inflammatory effect in murine activated neutrophils.
ADAR and Immune Silencing in Cancer.
ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis.
Adenosine Deaminase (ADA) Level in Tubercular Pleural Effusion.
Adenosine deaminase activity in a transplantable murine renal adenocarcinoma.
Adenosine deaminase activity in gastric cancer.
Adenosine deaminase activity in patients with carcinoma of the bladder.
Adenosine deaminase activity in patients with the intestinal type of gastric carcinoma.
Adenosine deaminase activity in peripheral blood cells of patients with haematological malignancies.
Adenosine deaminase activity in peripheral lymphocytes of patients with gynaecologic malignancies.
Adenosine deaminase activity in the diagnosis of tuberculous peritonitis.
Adenosine deaminase activity in the serum and malignant tumors of breast cancer: the assessment of isoenzyme ADA1 and ADA2 activities.
Adenosine deaminase activity: to be an useful marker in distinguishing pleural effusions due to malignancy from tuberculosis.
Adenosine deaminase and adenosine kinase in rat hepatomas and kidney tumours.
Adenosine deaminase and AMP deaminase activities in blood of cancer patients.
Adenosine deaminase and purine nucleoside phosphorylase activities in peripheral lymphocytes from patients with solid tumours.
Adenosine deaminase and purine phosphorylase activities in lymphocytes and red blood cells of patients with carcinoma of the larynx.
ADENOSINE DEAMINASE AND XANTHINE OXIDASE ACTIVITIES IN TUMOR BEARING RATS.
Adenosine deaminase complexing protein (ADCP): a transformation sensitive protein with potentials of a cancer marker.
Adenosine deaminase in cell transformation. Biophysical manifestation of membrane dynamics.
Adenosine deaminase in childhood malignancy: should there be a second look?
Adenosine deaminase inhibition suppresses progression of 4T1 murine breast cancer by adenosine receptor-dependent mechanisms.
Adenosine deaminase levels in blood type A patients with metastatic tumor.
Adenosine Deaminase That Acts on RNA 3 (ADAR3) Binding to Glutamate Receptor Subunit B Pre-mRNA Inhibits RNA Editing in Glioblastoma.
Adenosine deaminase, nucleoside phorphorylase and xanthine oxidase in liver tumours.
Adenosine deaminase, xanthine oxidase, superoxide dismutase, glutathione peroxidase activities and malondialdehyde levels in the sera of patients with head and neck carcinoma.
Adenosine inhibition of lymphocyte-mediated cytolysis: possible role of cyclic adenosine monophosphate.
Adenosine inhibits tumor cell invasion via receptor-independent mechanisms.
Adenosine receptor mRNA expression in normal and failing minipig hearts.
Adenosine receptors in colon carcinoma tissues and colon tumoral cell lines: focus on the A(3) adenosine subtype.
Age- and gender-specific epistasis between ADA and TNF-? influences human life-expectancy.
Alteration of adenosine deaminase levels in peripheral blood lymphocytes of patients with gastric cancer.
Alterations in erythrocyte adenine nucleotide pools resulting from 2'-deoxycoformycin therapy.
Antigenicity of UV radiation-induced murine tumors correlates positively with the level of adenosine deaminase activity.
Are contemporary methods for somatic gene therapy suitable for clinical applications?
Association of severe and fatal infections and treatment with pentostatin.
ATP depletion as a consequence of adenosine deaminase inhibition in man.
Autoinflammatory diseases in childhood, part 1: monogenic syndromes.
Beneficial effect of Ageratum conyzoides Linn (Asteraceae) upon inflammatory response induced by carrageenan into the mice pleural cavity.
Cancer in families with severe combined immune deficiency.
CD26 in T-cell lymphomas: a potential clinical role?
CECR1-mediated cross talk between macrophages and vascular mural cells promotes neovascularization in malignant glioma.
Cell proliferation in the thymus of Ehrlich ascites tumor bearing mice.
Characterization of adenosine deaminase from normal colon and colon tumors. Evidence for tumor-specific variants.
Chemopreventive task of capsaicin against benzo(a)pyrene-induced lung cancer in Swiss albino mice.
Cladribine. Ortho Biotech Inc.
Clinical response to deoxycoformycin in chronic lymphoid neoplasms and biochemical changes in circulating malignant cells in vivo.
Clinical significance of serum adenosine deaminase activity in patients with mycosis fungoides.
Clinical utility of pleural fluid YKL-40 as a marker of malignant pleural effusion.
Connecting p63 to cellular proliferation: the example of the adenosine deaminase target gene.
Conversion of asymptomatic infection to symptomatic visceral leishmaniasis: A study of possible immunological markers.
Decreased adenosine deaminase activity in peripheral lymphocytes from tumor patients with metastasis.
Decreased lymphocyte adenosine deaminase activity in tumor patients.
Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs toward malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo.
Diagnosing malignant pleural effusion using clinical and analytical parameters.
Diagnostic accuracy of tumor necrosis factor-alpha, interferon-gamma, interlukine-10 and adenosine deaminase 2 in differential diagnosis between tuberculous pleural effusion and malignant pleural effusion.
Diagnostic Performance of Different Pleural Fluid Biomarkers in Tuberculous Pleurisy.
Diagnostic Value of Interferon-Gamma Release Assays Combined with Multiple Indicators for Tuberculous Peritonitis.
Differential diagnosis of tuberculous and malignant pleural effusions: comparison of the Th1/Th2 cytokine panel, tumor marker panel and chemistry panel.
Discrimination of exudative pleural effusions based on multiple biological parameters.
Distinction of seventy-one cultured human tumor cell lines by polymorphic enzyme analysis.
Distribution and inhibition of adenosine deaminase in tissues of man, rat, and mouse.
Ectonucleotide Pyrophosphatase/Phosphodiesterase (E-NPP) and Adenosine Deaminase (ADA) activities in patients with uterine cervix neoplasia.
Effect of infliximab on renal injury due to methotrexate in rat.
Effect of novel A2A adenosine receptor agonist ATL 313 on Clostridium difficile toxin A-induced murine ileal enteritis.
Enzyme activities of leukemic cells and biochemical changes induced by deoxycoformycin in vitro--lack of correlation with clinical response.
Enzymes of purine metabolism in hairy cell leukemia.
Establishment of monoclonal anti-human CD26 antibodies suitable for immunostaining of formalin-fixed tissue.
Etanercept administration prevents the inflammatory response induced by carrageenan in the murine air pouch model.
Etiology and pleural fluid characteristics of large and massive effusions.
Evaluation of adenosine deaminase (ADA) isoenzymes activity and tumor necrosis factor-? (TNF?) concentration in chronic heart failure.
Evaluation of serum adenosine deaminase and 5'-nucleotidase activities as probable markers in ovarian cancer.
Function of low ADARB1 expression in lung adenocarcinoma.
Gastrointestinal tumor markers, other than carcinoembryonic antigen, and alpha fetal protein.
Gene technology based therapies in the brain.
Gene therapy for ovarian carcinoma.
Gene therapy techniques.
Gene transfer and antisense nucleic acid techniques.
Genetic expression of adenosine deaminase in human lymphoid malignancies.
Genetic variability within Adenosine Deaminase gene and uterine leiomyomas.
Growth Parameters of Turkish Children With an Autoinflammatory Disease Before and After Canakinumab Treatment.
Hematologic Manifestations of Deficiency of Adenosine Deaminase 2 (DADA2) and Response to Tumor Necrosis Factor Inhibition in DADA2-Associated Bone Marrow Failure.
Heterogeneity of isozyme expression in tumor cells does not correlate with metastatic potential.
Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation.
Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells.
Identification of transgelin as a potential novel biomarker for gastric adenocarcinoma based on proteomics technology.
In cancer, A-to-I RNA editing can be the driver, the passenger, or the mechanic.
Induction of differentiation of human myeloid leukemia cells by 2'-deoxycoformycin in combination with 2'-deoxyadenosine.
Inhibition of the NF-?B and p38 MAPK pathways by scopoletin reduce the inflammation caused by carrageenan in the mouse model of pleurisy.
Kinetics of some immunological and biochemical changes of immunocompetent cells during tumor growth in rats.
Levels of adenosine deaminase in some experimental animal tumours and the possible therapeutic effect of the ADA inhibitor 2-deoxy-coformycin.
Low-dose deoxycoformycin in lymphoid malignancy.
Lymphocytes as cellular vehicles for gene therapy in mouse and man.
Membrane phenotype and response to deoxycoformycin in mature T cell malignancies.
Memory of extracellular adenosine A2A purinergic receptor-mediated signaling in murine T cells.
Merits of HPLC-based method over spectrophotometric method for assessing the kinetics and inhibition of mammalian adenosine deaminase.
MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth.
Modulatory effect of mycophenolate mofetil on carrageenan-induced inflammation in the mouse air pouch model.
Molecular characterization as a target for cancer therapy in relation to orphan status disorders (Review).
Monoclonal antibody and enzymatic profiles of human malignant T-lymphoid cells and derived cell lines.
Mycophenolate Mofetil Has Potent Anti-inflammatory Actions in a Mouse Model of Acute Lung Injury.
Neopterin, soluble interleukin-2 receptor and adenosine deaminase levels in pleural effusions.
New scoring system using tumor markers in diagnosing patients with moderate pericardial effusions.
Normal Tumor Markers and Increased Adenosine Deaminase in Pericardial Effusion Misdiagnosed as Tuberculous Pericarditis Ultimately Proven as Lung Adenocarcinoma with Pericardial Metastasis: a Case Report and Literature Review.
On the regulatory role of dipeptidyl peptidase IV (=CD=adenosine deaminase complexing protein) on adenosine deaminase activity.
Opposite effects of recombinant interferon-alpha A and deoxycoformycin on adenosine deaminase activity in the Daudi B lymphoblastoid cell line.
Optimising the utility of pleural fluid adenosine deaminase for the diagnosis of adult tuberculous pleural effusion in Hong Kong.
Overexpression of adenosine deaminase acting on RNA 1 in chordoma tissues is associated with chordoma pathogenesis by reducing miR?125a and miR?10a expression.
Oxidative stress parameters and inflammatory and immune mediators as markers of the severity of sepsis.
Pentostatin (2'deoxycoformycin) for the treatment of lymphoid neoplasms.
Pentostatin treatment of cutaneous T-cell lymphoma.
Phase II study of cladribine (2-chlorodeoxyadenosine) in relapsed or refractory adult T-cell leukemia-lymphoma.
Plasma adenosine deaminase activity among HIV1 Clade C seropositives: relation to CD4 T cell population and antiretroviral therapy.
Plasma adenosine deaminase activity in tumour cases.
Plasma adenosine deaminase isoform 2 in cancer patients undergoing chemotherapy.
Pleural Fluid Adenosine Deaminase (ADA) Predicts Survival in Patients with Malignant Pleural Effusion.
Potent antitumor and antineoplastic efficacy of baicalein on benzo(a)pyrene-induced experimental pulmonary tumorigenesis.
Potential of gene therapy in bone marrow transplantation.
PPAR-Gamma Agonist Rosiglitazone Attenuates the Inflammation Caused by Carrageenan in the Mouse Model of Pleurisy.
Predicting malignant and tuberculous pleural effusions through demographics and pleural fluid analysis of patients.
Predictive Factors and Treatment Outcomes of Tuberculous Pleural Effusion in Patients With Cancer and Pleural Effusion.
Prognostic significance of adenosine deaminase in children with malignancies.
Purine analogs in chronic lymphocytic leukemia and Waldenström's macroglobulinemia.
Purine degradative enzymes and immunological phenotypes in chronic B-lymphocytic leukaemia: indications that leukaemic immunocytoma is a separate entity.
Purine degradative enzymes in circulating malignant cells of patients with chronic B cell neoplasia.
Purine metabolism in feline lymphomas.
Purine metabolism, immune reconstitution, and abdominal adipose tumor after gene therapy for adenosine deaminase deficiency.
Purine-Metabolising Enzymes and Apoptosis in Cancer.
Quantitative changes in adenosine deaminase isoenzymes in human colorectal adenocarcinomas.
Rapid, reliable, and sensitive detection of adenosine deaminase activity by UHPLC-Q-Orbitrap HRMS and its application to inhibitory activity evaluation of traditional Chinese medicines.
Rational design of arabinosyl nucleosides as antitumor and antiviral agents.
Relation between enzymatic activities and the degree of malignancy of human lymphomas.
Relationship between the levels of purine salvage pathway enzymes and clinical/biological aggressiveness of human colon carcinoma.
Repeated Electroacupuncture Persistently Elevates Adenosine and Ameliorates Collagen-Induced Arthritis in Rats.
Reynoutria Japonica from Traditional Chinese Medicine: A Source of Competitive Adenosine Deaminase Inhibitors for Anticancer.
Role of adenosine deaminase in human monocyte differentiation and tumor cell cytotoxicity.
Role of ascites adenosine deaminase in differentiating between tuberculous peritonitis and peritoneal carcinomatosis.
Role of IS6110-targeted PCR, culture, biochemical, clinical, and immunological criteria for diagnosis of tuberculous meningitis.
Serum adenosine deaminase activity in brain tumours.
Serum adenosine deaminase activity in cancer.
Serum adenosine deaminase enzyme and plasma platelet factor 4 activities in active pulmonary tuberculosis, HIV-seropositive subjects and cancer patients.
Serum adenosine deaminase in pulmonary tuberculosis, malignancy and non-tubercular respiratory diseases.
Serum adenosine deaminase levels as an index of tumor growth in head and neck malignancy.
Serum adenosine deaminase, 5'-nucleotidase & alkaline phosphatase in breast cancer patients.
Serum adenosine deaminase, catalase and carbonic anhydrase activities in patients with bladder cancer.
Serum adenosine deaminase, catalase, and carbonic anhydrase activities in patients with renal cell carcinoma.
Studies on the mechanism of cytotoxicity of 3'-deoxyadenosine N1-oxide in different strains of Ehrlich ascites tumor cells.
Synergistic Activity of an Antimetabolite Drug and Tyrosine Kinase Inhibitors against Breast Cancer Cells.
Synergistic effect of 3'-deoxyadenosine N1-oxide and adenosine deaminase inhibitors on growth of Ehrlich ascites tumor cells in vivo.
Systemic Administration of Calea pinnatifida Inhibits Inflammation Induced by Carrageenan in a Murine Model of Pulmonary Neutrophilia.
The anti-inflammatory modulatory role of Solidago chilensis Meyen in the murine model of the air pouch.
The correlation of adenosine deaminase and purine nucleoside phosphorylase activities in human lymphocytes subpopulations and in various lymphoid malignancies.
The diagnostic and prognostic value of adenosine deaminase in tuberculous pericarditis.
The diagnostic utility of pleural markers for tuberculosis pleural effusion.
The effect of pleural fluid content on the development of pleural thickness.
The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine.
The Impact of Purinergic System Enzymes on Noncommunicable, Neurological, and Degenerative Diseases.
The potentiation of radiation response on murine tumor by fludarabine phosphate.
To edit or not to edit: regulation of ADAR editing specificity and efficiency.
Tomato (Solanum lycopersicum) carotenoids & lycopenes chemistry; Metabolism, absorption, nutrition and allied health claims- A comprehensive review.
Towards gene therapy for the central nervous system.
Tumor markers in pleural effusion diagnosis.
Tumour necrosis factor, interleukin-1 and adenosine deaminase in tuberculous pleural effusion.
Tumour necrosis factor-alpha in comparison to adenosine deaminase in tuberculous pleuritis.
Vitamin U has a protective effect on valproic acid-induced renal damage due to its anti-oxidant, anti-inflammatory, and anti-fibrotic properties.
Wnt and beta-catenin signaling target the expression of ecto-5'-nucleotidase and increase extracellular adenosine generation.
[A case of CD56 positive T-cell lymphoma originating from mediastinal lymph nodes]
[Activity of adenosine metabolism enzymes and spontaneous chemiluminescence in macrophages in the tumor growth process]
[Adenosine deaminase activity in hemoblastoses]
[Adenosine deaminase activity in hepatomas of varying degrees of malignancy]
[Adenosine deaminase activity in the plasma of women with genital tumors.]
[Adenosine deaminase in tumors: a marker of the pleural invasion of lymphoproliferative processes?]
[Adenosine deaminase. Molecular variability in human neoplasms]
[Age-dependent characteristics of metabolism of DNA precursors in healthy women, patients with mastopathy and breast cancer]
[Clinical significance of cytokine measurement in pleural effusion]
[Dynamics of the cytokines, homocysteine contents, indices of oxydative and nitrosative stress and cytopathic hypoxia in patients after cholecystectomy for acute cholecystitis. Connection with rate of postoperative purulent-inflammatory complications]
[Enzymatic activity of serum adenosine deaminase in different liver disorders]
[Enzymes of adenosine metabolism in lymphocytes and the functional state of the sympatho-adrenal system in tumor processes]
[Evaluation of cerebrospinal fluid and blood adenosine deaminase activity in nervous system tumors.]
[Lactate dehydrogenase, adenosine deaminase and thymidine phosphorylase activity of blood and tissues in breast tumor patients]
[Measurement of adenosine deaminase activity in blood plasma as tumor diagnostic test.]
[Metformin impact on purine metabolism in breast cancer].
[Studies on increase of diagnostic possibilities in cancer; determination of activity of adenosine deaminase in plasma.]
[The pool of free purine and pyrimidine nucleosides and bases in the thymocytes, and splenic T- and B-lymphocytes of C3HA mice during the growth of solid hepatoma 22a]
[Transgenesis and gene therapy]
Nephrotic Syndrome
Adenosine deaminase activity in nephrotic syndrome.
Lymphocyte adenosine deaminase activity in children with idiopathic nephrotic syndrome.
Nervous System Diseases
Diagnostic value of cerebrospinal fluid adenosine deaminase determination.
Nervous System Malformations
Activity of adenosine deaminase in mothers who have conceived a fetus with central nervous system malformations.
Nervous System Neoplasms
[Evaluation of cerebrospinal fluid and blood adenosine deaminase activity in nervous system tumors.]
Neuralgia
RNA editing enzyme ADAR2 is a mediator of neuropathic pain after peripheral nerve injury.
Neuroblastoma
Control of cyclic adenosine 3':5'-monophosphate-elevating effect of adenosine in C-1300 murine neuroblastoma in tissue culture.
Effects of exogenous adenosine deaminase and erythro-9-(2-hydroxy-3-nonyl) adenine on intracellular cyclic AMP levels in C1300 murine neuroblastoma in tissue culture.
In vitro ultrastructural localization of the catalytic activity of adenosine deaminase in murine C-1300 neuroblastoma.
Mitochondrial Damage and Apoptosis Induced by Adenosine Deaminase Inhibition and Deoxyadenosine in Human Neuroblastoma Cell Lines.
Neurodegenerative Diseases
Co-administration of adenosine kinase and deaminase inhibitors produces supra-additive potentiation of N-methyl-D-aspartate-evoked adenosine formation in cortex.
Neurofibrosarcoma
cDNA microarray analysis of cancer associated gene expression profiles in malignant peripheral nerve sheath tumours.
Neurologic Manifestations
A 9.5-year-old boy with recurrent neurological manifestations and severe hypertension, treated initially for polyarteritis nodosa, was subsequently diagnosed with adenosine deaminase type 2 deficiency (DADA2) which responded to anti-TNF-?.
Neutropenia
Neutropenia among patients with adenosine deaminase deficiency.
Neutropenia and myeloid dysplasia in a patient with delayed-onset adenosine deaminase def