Disease on EC 3.4.23.B10 - Rous sarcoma virus retropepsin
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Acquired Immunodeficiency Syndrome
A cell-penetrating helical peptide as a potential HIV-1 inhibitor.
Acquired Immunodeficiency Syndrome
Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations.
Acquired Immunodeficiency Syndrome
Human immunodeficiency virus type-1 accessory protein Vpr: a causative agent of the AIDS-related insulin resistance/lipodystrophy syndrome?
Acquired Immunodeficiency Syndrome
Reversal of HIV drug resistance and novel strategies to curb HIV infection: the viral infectivity factor Vif as a target and tool of therapy.
Acquired Immunodeficiency Syndrome
The Current Recommended Drugs and Strategies for the Treatment of Coronavirus Disease (COVID-19).
Adenocarcinoma of Lung
Jaagsiekte sheep retrovirus is not detected in human lung adenocarcinomas expressing antigens related to the Gag polyprotein of betaretroviruses.
Adenomatous Polyposis Coli
The tumour suppressor APC promotes HIV-1 assembly via interaction with Gag precursor protein.
Adenoviridae Infections
Detection and Quantification of Label-Free Infectious Adenovirus Using a Switch-On Cell-Based Fluorescent Biosensor.
Adenoviridae Infections
Inhibition of adenovirus infection and adenain by green tea catechins.
Alzheimer Disease
Expression of the plant viral protease NIa in the brain of a mouse model of Alzheimer's disease mitigates A? pathology and improves cognitive function.
Anemia
Equine infectious anemia virus Gag polyprotein late domain specifically recruits cellular AP-2 adapter protein complexes during virion assembly.
Anemia
Functional replacement and positional dependence of homologous and heterologous L domains in equine infectious anemia virus replication.
Anemia
Functional roles of equine infectious anemia virus Gag p9 in viral budding and infection.
Anemia, Hemolytic
Sequences responsible for the distinctive hemolytic potentials of Friend and Moloney murine leukemia viruses are dispersed but confined to the psi-gag-PR region.
Angina Pectoris
The chemistry and pharmacology of alkaloids and allied nitrogen compounds from Artemisia species: A review.
Avian Leukosis
Proteolytic cleavage at the Gag-Pol junction in avian leukosis virus: differences in vitro and in vivo.
Avian Leukosis
trans-acting viral protease is necessary and sufficient for activation of avian leukosis virus reverse transcriptase.
Carcinoma
Immunohistochemical determination of the P15 protein expression in cutaneous squamous cell carcinoma.
Carcinoma, Hepatocellular
Innate immune response induced by baculovirus attenuates transgene expression in mammalian cells.
Carcinoma, Squamous Cell
Immunohistochemical determination of the P15 protein expression in cutaneous squamous cell carcinoma.
Cardiomyopathies
Nitric oxide inhibits dystrophin proteolysis by coxsackieviral protease 2A through S-nitrosylation: A protective mechanism against enteroviral cardiomyopathy.
Coronavirus Infections
Identification of lead compounds from large natural product library targeting 3C-like protease of SARS-CoV-2 using E-pharmacophore modelling, QSAR and molecular dynamics simulation.
COVID-19
Analysis of the efficacy of HIV protease inhibitors against SARS-CoV-2's main protease.
COVID-19
Carvacrol, a Plant Metabolite Targeting Viral Protease (Mpro) and ACE2 in Host Cells Can Be a Possible Candidate for COVID-19.
COVID-19
Computation screening and molecular docking of FDA approved viral protease inhibitors as a potential drug against COVID-19.
COVID-19
Evaluation of the Binding Affinity of Anti-Viral Drugs against Main Protease of SARS-CoV-2 through a Molecular Docking Study.
COVID-19
In silico analysis of phytochemicals as potential inhibitors of proteases involved in SARS-CoV-2 infection.
COVID-19
Molecular modeling study of tectoquinone and acteoside from Tectona grandis linn: a new SARS-CoV-2 main protease inhibitor against COVID-19.
COVID-19
Role of Iron Chelation and Protease Inhibition of Natural Products on COVID-19 Infection.
COVID-19
The Current Recommended Drugs and Strategies for the Treatment of Coronavirus Disease (COVID-19).
Coxsackievirus Infections
Viral protease cleavage of inhibitor of kappaBalpha triggers host cell apoptosis.
Dengue
Activation of dengue protease autocleavage at the NS2B-NS3 junction by recombinant NS3 and GST-NS2B fusion proteins.
Dengue
Cleavage of the dengue virus polyprotein at the NS3/NS4A and NS4B/NS5 junctions is mediated by viral protease NS2B-NS3, whereas NS4A/NS4B may be processed by a cellular protease.
Dengue
Construction of dengue virus protease expression plasmid and in vitro protease assay for screening antiviral inhibitors.
Dengue
Dengue viral protease interaction with NF-?B inhibitor ?/? results in endothelial cell apoptosis and hemorrhage development.
Dengue
Development and utility of an in vitro, fluorescence-based assay for the discovery of novel compounds against dengue 2 viral protease.
Dengue
Structural insights into a multifunctional inhibitor, 'AMTIN' from tubers of Alocasia macrorrhizos and its possible role in dengue protease (NS2B-NS3) inhibition.
Dengue
Synthesis and biological evaluation of ?-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture.
Diabetes Mellitus
Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations.
Encephalitis
Substrate-based peptidomimetic inhibitors of the Murray Valley encephalitis virus NS2B/NS3 serine protease: A P1-P4 SAR study.
Encephalitis, Japanese
Processing of Japanese encephalitis virus non-structural proteins: NS2B-NS3 complex and heterologous proteases.
Enzootic Bovine Leukosis
A new form of particulate single and multiple immunogen delivery system based on recombinant bluetongue virus-derived tubules.
Enzootic Bovine Leukosis
Bovine leukemia virus Gag particle assembly in insect cells: formation of chimeric particles by domain-switched leukemia/lentivirus Gag polyprotein.
Enzootic Bovine Leukosis
Involvement of the matrix and nucleocapsid domains of the bovine leukemia virus Gag polyprotein precursor in viral RNA packaging.
Equine Infectious Anemia
Equine infectious anemia virus Gag polyprotein late domain specifically recruits cellular AP-2 adapter protein complexes during virion assembly.
Equine Infectious Anemia
Functional replacement and positional dependence of homologous and heterologous L domains in equine infectious anemia virus replication.
Equine Infectious Anemia
Functional roles of equine infectious anemia virus Gag p9 in viral budding and infection.
Foot-and-Mouth Disease
Nucleotide and amino acid sequence coding for polypeptides of foot-and-mouth disease virus type A12.
Foot-and-Mouth Disease
Plant molecular farming of virus-like nanoparticles as vaccines and reagents.
Hand, Foot and Mouth Disease
Expression, purification and characterization of enterovirus-71 virus-like particles.
Hepatitis A
Comparative evaluation of new TaqMan real-time assays for the detection of hepatitis A virus.
Hepatitis B
A new form of particulate single and multiple immunogen delivery system based on recombinant bluetongue virus-derived tubules.
Hepatitis C
A drug repurposing screen identifies hepatitis C antivirals as inhibitors of the SARS-CoV2 main protease.
Hepatitis C
Amantadine and rimantadine have no direct inhibitory effects against hepatitis C viral protease, helicase, ATPase, polymerase, and internal ribosomal entry site-mediated translation.
Hepatitis C
Coronaviruses resistant to a 3C-like protease inhibitor are attenuated for replication and pathogenesis, revealing a low genetic barrier but high fitness cost of resistance.
Hepatitis C
Curing a viral infection by targeting the host: the example of cyclophilin inhibitors.
Hepatitis C
Global Origin and Transmission of Hepatitis C Virus Nonstructural Protein 3 Q80K Polymorphism.
Hepatitis C
HCV protease inhibitory, cytotoxic and apoptosis-inducing effects of oleanolic acid derivatives.
Hepatitis C
Hepatitis C virus/human interactome identifies SMURF2 and the viral protease as critical elements for the control of TGF-? signaling.
Hepatitis C
High-throughput cell-based screening for hepatitis C virus NS3/4A protease inhibitors.
Hepatitis C
Improving the Resistance Profile of Hepatitis C NS3/4A Inhibitors: Dynamic Substrate Envelope Guided Design.
Hepatitis C
Inhibition of both protease and helicase activities of hepatitis C virus NS3 by an ethyl acetate extract of marine sponge Amphimedon sp.
Hepatitis C
Innate immune response induced by baculovirus attenuates transgene expression in mammalian cells.
Hepatitis C
Limited effect on NS3-NS4A protein cleavage after alanine substitutions within the immunodominant HLA-A2-restricted epitope of the hepatitis C virus genotype 3a non-structural 3/4A protease.
Hepatitis C
Molecular characterization of hepatitis C virus for determination of subtypes and detection of resistance mutations to protease inhibitors in a group of intravenous drug users co-infected with HIV.
Hepatitis C
Pharmacokinetic characteristics of telaprevir in healthy Korean male subjects and comparisons with Japanese.
Hepatitis C
Production of nonstructural proteins of hepatitis C virus requires a putative viral protease encoded by NS3.
Hepatitis C
Recombinant adeno-associated virus expressing a modified transcription factor triggered by the hepatitis C viral protease NS3/4a.
Hepatitis C
Safety of Hepatitis C Viral Protease Inhibitors in Compensated Cirrhotics: Lingering Concerns Put to Rest?
Hepatitis C
SCREENING OF PROTEASE INHIBITORS RESISTANCE MUTATIONS IN HEPATITIS C VIRUS ISOLATES INFECTING ROMANIAN PATIENTS UNEXPOSED TO TRIPLE THERAPY.
Hepatitis C
Validating Enterovirus D68-2Apro as an Antiviral Drug Target and the Discovery of Telaprevir as a Potent D68-2Apro Inhibitor.
Herpes Simplex
The putative herpes simplex virus 1 chaperone protein UL32 modulates disulfide bond formation during infection.
HIV Infections
Proteolytic events of HIV-1 replication as targets for therapeutic intervention.
HIV Infections
Understanding the HIV-1 protease nelfinavir resistance mutation D30N in subtypes B and C through molecular dynamics simulations.
Hyperlipidemias
Mitochondria in the pathogenesis of lipodystrophy induced by anti-HIV antiretroviral drugs: actors or bystanders?
Infections
Aberrant PD-1 ligand expression contributes to the myocardial inflammatory injury caused by Coxsackievirus B infection.
Infections
An Overview of Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy.
Infections
Characterization of human immunodeficiency virus type 1 (HIV-1) containing mutations in the nucleocapsid protein at a putative HIV-1 protease cleavage site.
Infections
Citrus Psorosis Virus Movement Protein Contains an Aspartic Protease Required for Autocleavage and the Formation of Tubule-Like Structures at Plasmodesmata.
Infections
Cleavage of sequestosome 1/p62 by an enteroviral protease results in disrupted selective autophagy and impaired NFKB signaling.
Infections
Conditional human immunodeficiency virus type 1 protease mutants show no role for the viral protease early in virus replication.
Infections
Contribution of PDZD8 to Stabilization of the Human Immunodeficiency Virus Type 1 Capsid.
Infections
Coxsackievirus Counters the Host Innate Immune Response by Blocking Type III Interferon Expression.
Infections
Cytoplasmic translocation, aggregation, and cleavage of TDP-43 by enteroviral proteases modulate viral pathogenesis.
Infections
Cytoskeletal association of an aphthovirus-induced polypeptide derived from the P3ABC region of the viral polyprotein.
Infections
Effect of internal cleavage site mutations in human immunodeficiency virus type 1 capsid protein on its structure and function.
Infections
Foot-and-Mouth Disease Virus Counteracts on Internal Ribosome Entry Site Suppression by G3BP1 and Inhibits G3BP1-Mediated Stress Granule Assembly via Post-Translational Mechanisms.
Infections
Identification of mixed HIV-1/HIV-2 infections in Brazil by polymerase chain reaction.
Infections
Identification of single and dual infections with distinct subtypes of human immunodeficiency virus type 1 by using restriction fragment length polymorphism analysis.
Infections
Intracellularly expressed single-domain antibody against p15 matrix protein prevents the production of porcine retroviruses.
Infections
N-Naphthoyl-substituted indole thio-barbituric acid analogs inhibit the helicase activity of the hepatitis C virus NS3.
Infections
Nidovirus papain-like proteases: Multifunctional enzymes with protease, deubiquitinating and deISGylating activities.
Infections
Nuclear entry of poliovirus protease-polymerase precursor 3CD: implications for host cell transcription shut-off.
Infections
Peptidyl-prolyl cis-trans isomerases, a superfamily of ubiquitous folding catalysts.
Infections
Pharmacokinetic characteristics of telaprevir in healthy Korean male subjects and comparisons with Japanese.
Infections
Recombinant adeno-associated virus expressing a modified transcription factor triggered by the hepatitis C viral protease NS3/4a.
Infections
SCREENING OF PROTEASE INHIBITORS RESISTANCE MUTATIONS IN HEPATITIS C VIRUS ISOLATES INFECTING ROMANIAN PATIENTS UNEXPOSED TO TRIPLE THERAPY.
Infections
Structural and molecular determinants of HIV-1 Gag binding to the plasma membrane.
Infections
The impact of genetic variation in IL28B, IFNL4 and HLA genes on treatment responses against chronic hepatitis C virus infection.
Infections
The mammalian host protein DAP5 facilitates the initial round of translation of Coxsackievirus B3 RNA.
Influenza, Human
Analysis of bovine leukemia virus gag membrane targeting and late domain function.
Influenza, Human
Plant molecular farming of virus-like nanoparticles as vaccines and reagents.
Influenza, Human
The Current Recommended Drugs and Strategies for the Treatment of Coronavirus Disease (COVID-19).
Insulin Resistance
Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations.
Insulin Resistance
Mitochondria in the pathogenesis of lipodystrophy induced by anti-HIV antiretroviral drugs: actors or bystanders?
Leukemia
An internal ribosomal entry mechanism promotes translation of murine leukemia virus gag polyprotein precursors.
Leukemia
Avian sarcoma leukemia virus protease linked to the adjacent Gag polyprotein is enzymatically active.
Leukemia
Construction and characterization of Moloney murine leukemia virus mutants unable to synthesize glycosylated gag polyprotein.
Leukemia
Cooperative effect of gag proteins p12 and capsid during early events of murine leukemia virus replication.
Leukemia
Genetic control of natural immunity to ecotropic mouse leukemia viruses: immune response genes.
Leukemia
HIV-1 Matrix Trimerization-Impaired Mutants Are Rescued by Matrix Substitutions That Enhance Envelope Glycoprotein Incorporation.
Leukemia
Immune response of the mouse to the major core protein (p30) of ecotropic leukemia viruses.
Leukemia
Localization of actin in Moloney murine leukemia virus by immunoelectron microscopy.
Leukemia
Murine leukemia virus glycosylated Gag (gPr80gag) facilitates interferon-sensitive virus release through lipid rafts.
Leukemia
Mutation in the glycosylated gag protein of murine leukemia virus results in reduced in vivo infectivity and a novel defect in viral budding or release.
Leukemia
Mutations at the capsid-nucleocapsid cleavage site of gag polyprotein of Moloney murine leukemia virus abolish virus infectivity.
Leukemia
Mutations in the cytoplasmic tail of murine leukemia virus envelope protein suppress fusion inhibition by R peptide.
Leukemia
Promyelocytic Leukemia Restricts Enterovirus 71 Replication by Inhibiting Autophagy.
Leukemia
Replication of human immunodeficiency virus 1 and Moloney murine leukemia virus is inhibited by different heteroatom-containing analogs of myristic acid.
Leukemia
The Cellular Protein La Functions in Enhancement of Virus Release through Lipid Rafts Facilitated by Murine Leukemia Virus Glycosylated Gag.
Leukemia
The effect of cerulenin on the synthesis of the precursor gag polyprotein in defective murine leukemia and sarcoma virus producing cell lines.
Leukemia
The nucleocapsid domain is responsible for the ability of spleen necrosis virus (SNV) Gag polyprotein to package both SNV and murine leukemia virus RNA.
Leukemia
Viral interactions with the host-cell cytoskeleton: the role of retroviral proteases.
Leukemia, Feline
Mutation in the glycosylated gag protein of murine leukemia virus results in reduced in vivo infectivity and a novel defect in viral budding or release.
Leukemia, T-Cell
PPPYVEPTAP motif is the late domain of human T-cell leukemia virus type 1 Gag and mediates its functional interaction with cellular proteins Nedd4 and Tsg101 [corrected].
Lipodystrophy
Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations.
Lipodystrophy
Mitochondria in the pathogenesis of lipodystrophy induced by anti-HIV antiretroviral drugs: actors or bystanders?
Liver Diseases
HCV protease inhibitory, cytotoxic and apoptosis-inducing effects of oleanolic acid derivatives.
Liver Diseases
Sofosbuvir (Sovaldi°). Active against hepatitis C virus, but evaluation is incomplete .
Lymphatic Metastasis
[Expression of p15 protein in poorly differentiated nasopharyngeal carcinoma]
Mouth Diseases
Expression, purification and characterization of enterovirus-71 virus-like particles.
Mouth Diseases
Plant molecular farming of virus-like nanoparticles as vaccines and reagents.
Murine Acquired Immunodeficiency Syndrome
CTL responses to the gag polyprotein encoded by the murine AIDS defective retrovirus are strain dependent.
Murine Acquired Immunodeficiency Syndrome
STAT6-deficient mice exhibit normal induction of murine AIDS and expression of immunoglobulin E following infection with LP-BM5 murine leukemia viruses.
Nasopharyngeal Carcinoma
[Expression of p15 protein in poorly differentiated nasopharyngeal carcinoma]
Neoplasm Metastasis
[Expression of p15 protein in poorly differentiated nasopharyngeal carcinoma]
Neoplasms
Alterations of INK4a(p16-p14ARF)/INK4b(p15) expression and telomerase activation in meningioma progression.
Neoplasms
Cyclin-Dependent Kinase Inhibitor 2b Controls Fibrosis and Functional Changes in Ischemia-Induced Heart Failure via the BMI1-p15-Rb Signalling Pathway.
Neoplasms
Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.
Neoplasms
Membrane properties of the gag gene-coded p15 protein of mouse type-C RNA tumor viruses.
Neoplasms
Poliovirus 3C protease-mediated degradation of transcriptional activator p53 requires a cellular activity.
Neoplasms
Premature processing of mouse mammary tumor virus Gag polyprotein impairs intracellular capsid assembly.
Neoplasms
Seneca Valley Virus 3C Protease Induces Pyroptosis by Directly Cleaving Porcine Gasdermin D.
Neoplasms
The tumour suppressor APC promotes HIV-1 assembly via interaction with Gag precursor protein.
Pancreatitis, Acute Necrotizing
Active residues and viral substrate cleavage sites of the protease of the birnavirus infectious pancreatic necrosis virus.
Peritonitis
In silico and in vitro analysis of small molecules and natural compounds targeting the 3CL protease of feline infectious peritonitis virus.
Pulmonary Adenomatosis, Ovine
Jaagsiekte sheep retrovirus is not detected in human lung adenocarcinomas expressing antigens related to the Gag polyprotein of betaretroviruses.
Rubella
A cysteine-rich metal-binding domain from rubella virus non-structural protein is essential for viral protease activity and virus replication.
Sarcoma
Identification of a new viral protein containing CAp30 and NCp10 sequences in murine and feline leukemia retroviruses.
Sarcoma
The effect of cerulenin on the synthesis of the precursor gag polyprotein in defective murine leukemia and sarcoma virus producing cell lines.
Sarcoma, Avian
1H, 15N and 13C assignments of a monomeric N-terminal deletion mutant of the Rous sarcoma virus protease.
Sarcoma, Avian
Altered Rous sarcoma virus Gag polyprotein processing and its effects on particle formation.
Sarcoma, Avian
Amino acids encoded downstream of gag are not required by Rous sarcoma virus protease during gag-mediated assembly.
Sarcoma, Avian
Avian sarcoma leukemia virus protease linked to the adjacent Gag polyprotein is enzymatically active.
Sarcoma, Avian
Cleavage of four avian sarcoma virus polyproteins with virion protease p15 removes gag sequences and yields large fragments that function as tyrosine phosphoacceptors in vitro.
Sarcoma, Avian
Cleavage of the X-Pro peptide bond by pepsin is specific for the trans isomer.
Sarcoma, Avian
Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease.
Sarcoma, Avian
Deletion of a Cys-His motif from the Alpharetrovirus nucleocapsid domain reveals late domain mutant-like budding defects.
Sarcoma, Avian
Detailed mapping of the nuclear export signal in the Rous sarcoma virus Gag protein.
Sarcoma, Avian
Fine mapping and characterization of the Rous sarcoma virus Pr76gag late assembly domain.
Sarcoma, Avian
Importance of basic residues in binding of rous sarcoma virus nucleocapsid to the RNA packaging signal.
Sarcoma, Avian
Importance of the N terminus of rous sarcoma virus protease for structure and enzymatic function.
Sarcoma, Avian
Modeling of structure of human immunodeficiency virus-1 protease with substrate based on crystal structure of Rous sarcoma virus protease.
Sarcoma, Avian
Molecular mechanics calculations on Rous sarcoma virus protease with peptide substrates.
Sarcoma, Avian
Mutational analysis of the substrate binding pockets of the Rous sarcoma virus and human immunodeficiency virus-1 proteases.
Sarcoma, Avian
Mutations affecting cleavage at the p10-capsid protease cleavage site block Rous sarcoma virus replication.
Sarcoma, Avian
NMR Relaxation Studies of an RNA-Binding Segment of the Rous Sarcoma Virus Gag Polyprotein in Free and Bound States: A Model for Autoinhibition of Assembly.
Sarcoma, Avian
Nuclear entry and CRM1-dependent nuclear export of the Rous sarcoma virus Gag polyprotein.
Sarcoma, Avian
Overlapping roles of the Rous sarcoma virus Gag p10 domain in nuclear export and virion core morphology.
Sarcoma, Avian
Peptides derived from HIV-1 Vif: a non-substrate based novel type of HIV-1 protease inhibitors.
Sarcoma, Avian
Possible role of some groups in the structure and function of HIV-1 protease as revealed by molecular modeling studies.
Sarcoma, Avian
Production of Rous sarcoma virus-like particles displaying human transmembrane protein in silkworm larvae and its application to ligand-receptor binding assay.
Sarcoma, Avian
Programming the Rous sarcoma virus protease to cleave new substrate sequences.
Sarcoma, Avian
Proteases from human immunodeficiency virus and avian myeloblastosis virus show distinct specificities in hydrolysis of multidomain protein substrates.
Sarcoma, Avian
Proteolytic activity of purified avian sarcoma and leukemia virus NC-PR protein expressed in Escherichia coli.
Sarcoma, Avian
Requirement of N- and C-terminal regions for enzymatic activity of human T-cell leukemia virus type I protease.
Sarcoma, Avian
RNA-Binding Domains of Heterologous Viral Proteins Substituted for Basic Residues in the RSV Gag NC Domain Restore Specific Packaging of Genomic RNA.
Sarcoma, Avian
Role of the gag polyprotein precursor in packaging and maturation of Rous sarcoma virus genomic RNA.
Sarcoma, Avian
Site-directed mutagenesis of the P2 region of the Rous sarcoma virus gag gene: effects on Gag polyprotein processing.
Sarcoma, Avian
Structural basis for targeting avian sarcoma virus Gag polyprotein to the plasma membrane for virus assembly.
Sarcoma, Avian
Structure of the aspartic protease from Rous sarcoma retrovirus refined at 2-A resolution.
Starvation
Glutamine starvation of murine leukaemia virus-infected cells inhibits the readthrough of the gag-pol genes and proteolytic processing of the gag polyprotein.
Vaccinia
A synthetic HIV-1 protease inhibitor with antiviral activity arrests HIV-like particle maturation.
Vaccinia
Human immunodeficiency virus envelope protein determines the site of virus release in polarized epithelial cells.
Vaccinia
Identification of a region in the Pr55gag-polyprotein essential for HIV-1 particle formation.
Vaccinia
Processing of Japanese encephalitis virus non-structural proteins: NS2B-NS3 complex and heterologous proteases.
Vaccinia
Processing of the intracellular form of the west Nile virus capsid protein by the viral NS2B-NS3 protease: an in vitro study.
Vaccinia
Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.
Vaccinia
Studies on processing, particle formation, and immunogenicity of the HIV-1 gag gene product: a possible component of a HIV vaccine.
Viremia
Methylene blue is a potent and broad-spectrum inhibitor against Zika virus in vitro and in vivo.
Virus Diseases
Cytoplasmic viral RNA-dependent RNA polymerase disrupts the intracellular splicing machinery by entering the nucleus and interfering with Prp8.
Virus Diseases
Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease.
Virus Diseases
Inhibition of desipramine hydroxylation (Cytochrome P450-2D6) in vitro by quinidine and by viral protease inhibitors: relation to drug interactions in vivo.
Virus Diseases
Regulated Cleavages at the West Nile Virus NS4A-2K-NS4B Junctions Play a Major Role in Rearranging Cytoplasmic Membranes and Golgi Trafficking of the NS4A Protein.
Virus Diseases
Stimulation of the Internal Ribosome Entry Site (IRES)-Dependent Translation of Enterovirus 71 by DDX3X RNA Helicase and Viral 2A and 3C Proteases.
Virus Diseases
Substrate-based peptidomimetic inhibitors of the Murray Valley encephalitis virus NS2B/NS3 serine protease: A P1-P4 SAR study.
Virus Diseases
Subunit-specific analysis of the human immunodeficiency virus type 1 reverse transcriptase in vivo.
Virus Diseases
The C-terminal amyloidogenic peptide contributes to self-assembly of Avibirnavirus viral protease.
Visna
Truncation of the human immunodeficiency virus type 1 envelope glycoprotein allows efficient pseudotyping of Moloney murine leukemia virus particles and gene transfer into CD4+ cells.
West Nile Fever
Synthesis and biological evaluation of ?-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture.
Zika Virus Infection
Methylene blue is a potent and broad-spectrum inhibitor against Zika virus in vitro and in vivo.
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