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Information on EC 3.4.22.B79 - nsP2 protease and Organism(s) Murine coronavirus and UniProt Accession P0C6X9

for references in articles please use BRENDA:EC3.4.22.B79
preliminary BRENDA-supplied EC number
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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B79 nsP2 protease
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This record set is specific for:
Murine coronavirus
UNIPROT: P0C6X9
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Word Map
The taxonomic range for the selected organisms is: Murine coronavirus
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
the enzymes processes the alphavirus nonstructural polyprotein (nsP1234). The enzyme from Venezuelan equine encephalitis virus shwos a preferens for Gly or Als in position P1', Ala or Cys in P1, and Gly in P2
Synonyms
nonstructural protein 2, nonstructural polyprotein, nsp2 protease, nsp2 protein, nsp2pro, ns polyprotein, more
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
replicase polyprotein
UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
complete elimination of nonstructural proteins nsp1 and nsp2 does not abolish viral viability
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hurst-Hess, K.R.; Kuo, L.; Masters, P.S.
Dissection of amino-terminal functional domains of murine coronavirus nonstructural protein 3
J. Virol.
89
6033-6047
2015
Murine coronavirus (P0C6X9), Murine coronavirus A59 (P0C6X9)
Manually annotated by BRENDA team