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Adenocarcinoma
Characterisation of the complement-regulatory proteins decay-accelerating factor (DAF, CD55) and membrane cofactor protein (MCP, CD46) on a human colonic adenocarcinoma cell line.
Alzheimer Disease
HLA-linked complement markers in Alzheimer's and Parkinson's disease: C4 variant (C4B2) a possible marker for senile dementia of the Alzheimer type.
Arthritis
Genetic markers in rheumatoid arthritis.
Arthritis, Juvenile
[Genetic study of properdin factor B in juvenile rheumatoid arthritis]
Arthritis, Rheumatoid
Bf and C3 polymorphisms in rheumatoid arthritis.
Arthritis, Rheumatoid
Correlation between levels of breakdown products of C3, C4, and properdin factor B in synovial fluids from patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Depressed synovial fluid levels of properdin and properdin factor B in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Genetic variants of properdin factor B (Bf) in rheumatoid arthritis.
Arthritis, Rheumatoid
Properdin factor B and complement factor C4 allotypes in rheumatoid arthritis: results of a follow-up study.
Asthma
Inactivation of heamolytic complement by house dust allergen in the serum of children with atopic diseases.
Asthma
T and B lymphocytes, immunoglobulins and complement components in bronchial asthma.
Atypical Hemolytic Uremic Syndrome
C3 glomerulonephritis secondary to mutations in factors H and I: rapid recurrence in deceased donor kidney transplant effectively treated with eculizumab.
Atypical Hemolytic Uremic Syndrome
Disease-linked mutations in factor H reveal pivotal role of cofactor activity in self-surface-selective regulation of complement activation.
Bacteremia
Activation of the properdin pathway of complement in patients with gram-negative of bacteremia.
Bacterial Infections
The role of immune complexes in the pathogenesis of pleural effusions.
Caplan Syndrome
HLA-A, B and DR antigens and properdin factor B allotypes in Caplan's syndrome.
Carcinoma, Ehrlich Tumor
Further studies on cytolysis of Ehrlich ascites tumor cells brought into contact with normal human serum. The nature of the heat-labile factor.
Carcinoma, Hepatocellular
Complements as new diagnostic tools of hepatocellular carcinoma in cirrhotic patients.
Carcinoma, Hepatocellular
Soluble factors from liver and hepatomas which inhibit [3H]thymidine incorporation into DNA of Novikoff hepatoma cells.
Carcinoma, Hepatocellular
[A clinical study of complements as a marker of a hepatocellular carcinoma]
Celiac Disease
Properdin factor B and glyoxalase 1 polymorphism in celiac disease.
Colitis, Ulcerative
Complement inhibitors and immunoconglutinins in ulcerative colitis and Crohn's disease.
Colitis, Ulcerative
Humoral immune system in inflammatory bowel disease: I. Complement levels.
Connective Tissue Diseases
The role of immune complexes in the pathogenesis of pleural effusions.
Crohn Disease
Complement inhibitors and immunoconglutinins in ulcerative colitis and Crohn's disease.
Crohn Disease
Humoral immune system in inflammatory bowel disease: I. Complement levels.
Dermatitis, Atopic
Inactivation of heamolytic complement by house dust allergen in the serum of children with atopic diseases.
Diabetes Mellitus
Genetic heterogeneity of insulin-dependent (type I) diabetes mellitus: evidence from a study of extended haplotypes.
Diabetes Mellitus
Genetic polymorphism of properdin factor B (BF) in Chinese patients with two types of diabetes mellitus.
Diabetes Mellitus
Genetic susceptibility to diabetes mellitus: the distribution of properdin factor B (Bf) and glyoxalase (GLO) phenotypes.
Diabetes Mellitus, Type 1
A multicenter study on HLA and autoimmunity in Japanese patients with early-onset insulin-dependent diabetes mellitus (IDDM): the JDS Study.
Diabetes Mellitus, Type 1
Association studies between Type 1 (insulin-dependent) diabetes and 27 genetic markers: lack of association between Type 1 diabetes and Kidd blood group.
Diabetes Mellitus, Type 1
BF types and the mode of inheritance of insulin-dependent diabetes mellitus (IDDM).
Diabetes Mellitus, Type 1
Close genetic linkage between diabetes mellitus and kidd blood group.
Diabetes Mellitus, Type 1
Genetic marker for insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
Immunogenetics of early-onset insulin-dependent diabetes mellitus among the Japanese: HLA, Gm, BF, GLO, and organ-specific autoantibodies--the J.D.S. study.
Diabetes Mellitus, Type 1
Insulin-dependent diabetes mellitus and properdin factor B.
Diabetes Mellitus, Type 1
Lymphocytotoxic antibodies and histocompatibility antigens in juvenile-onset diabetes mellitus.
Diabetes Mellitus, Type 1
The HLAB*18,BF*F1 in haplotype in type 1 diabetes.
Diabetes Mellitus, Type 1
The search for heterogeneity in insulin-dependent diabetes mellitus (IDDM): linkage studies, two-locus models, and genetic heterogeneity.
Diabetes Mellitus, Type 2
Elevated Properdin and Enhanced Complement Activation in First-Degree Relatives of South Asian Subjects With Type 2 Diabetes.
Glomerulonephritis
A study of complement components C3, C5, C6, C7, C8 and C9 in chronic membranoproliferative glomerulonephritis, systemic lupus erythematosus, poststreptococcal nephritis, idiopathic nephrotic syndrome and anaphylactoid purpura.
Glomerulonephritis
An inherited defect in the C3 convertase, C3b,Bb, associated with glomerulonephritis.
Glomerulonephritis
Hereditary and acquired complement dysregulation in membranoproliferative glomerulonephritis.
Glomerulonephritis
Human anti-idiotypic antibody responses to autoantibody against the alternative pathway C3 convertase.
Glomerulonephritis
Properdin anc C3 proactivator: alternate pathway components in human glomerulonephritis.
Glomerulonephritis, IGA
Factor B subtypes in Japanese patients with IgA nephropathy and with idiopathic membranous nephropathy.
Glomerulonephritis, Membranoproliferative
A novel ELISA assay for the detection of C3 nephritic factor.
Glomerulonephritis, Membranoproliferative
Autoantibody to complement neoantigens in membranoproliferative glomerulonephritis.
Glomerulonephritis, Membranoproliferative
Autoimmune forms of thrombotic microangiopathy and membranoproliferative glomerulonephritis: Indications for a disease spectrum and common pathogenic principles.
Glomerulonephritis, Membranoproliferative
Biological significance of the C3 nephritic factor in membranoproliferative glomerulonephritis.
Glomerulonephritis, Membranoproliferative
C5 Convertase Blockade in Membranoproliferative Glomerulonephritis: A Single-Arm Clinical Trial.
Glomerulonephritis, Membranoproliferative
Clearances of complement components, C3 proactivator and other serum proteins in chronic membranoproliferative glomerulonephritis (CMPGN).
Glomerulonephritis, Membranoproliferative
Complement breakdown products in plasma from patients with systemic lupus erythematosus and patients with membranoproliferative or other glomerulonephritis.
Glomerulonephritis, Membranoproliferative
Hereditary and acquired complement dysregulation in membranoproliferative glomerulonephritis.
Glomerulonephritis, Membranoproliferative
Human anti-idiotypic antibody responses to autoantibody against the alternative pathway C3 convertase.
Glomerulonephritis, Membranoproliferative
Morphofunctional Effects of C5 Convertase Blockade in Immune Complex-Mediated Membranoproliferative Glomerulonephritis: Report of Two Cases with Evidence of Terminal Complement Activation.
Glomerulonephritis, Membranoproliferative
MPGN II--genetically determined by defective complement regulation?
Glomerulonephritis, Membranoproliferative
Nucleotide sequence of a human autoantibody to the alternative pathway C3/C5 convertase (C3NeF).
Glomerulonephritis, Membranoproliferative
Production of IgG and IgM autoantibody to the alternative pathway C3 convertase in normal individuals and patients with membranoproliferative glomerulonephritis.
Glomerulonephritis, Membranoproliferative
Selective disappearance of C3NeF IgG autoantibody in the plasma of a patient with membranoproliferative glomerulonephritis following renal transplantation.
Glomerulonephritis, Membranoproliferative
Study of the idiotypic response to autoantibody to the alternative pathway C3/C5 convertase in normal individuals, patients with membranoproliferative glomerulonephritis, and experimental animals.
Glomerulonephritis, Membranoproliferative
Two types of C3 nephritic factor: properdin-dependent C3NeF and properdin-independent C3NeF.
Glomerulonephritis, Membranoproliferative
[Direct detection C3bBb stabilizing activity in sera from hypocomplementaemic membranoproliferative glomerulonephritis (MPGN) and complement profiles of C3NeF positive cases]
Glomerulonephritis, Membranous
Factor B subtypes in Japanese patients with IgA nephropathy and with idiopathic membranous nephropathy.
Glomerulonephritis, Membranous
Properdin factor B alleles in patients with idiopathic membranous nephropathy.
Glucose Intolerance
Elevated Properdin and Enhanced Complement Activation in First-Degree Relatives of South Asian Subjects With Type 2 Diabetes.
Graves Disease
Properdin factor B (Bf) and glyoxalase in Graves' disease.
Guillain-Barre Syndrome
Complement factors and acute phase reactants in the Guillain-Barré syndrome.
Hemoglobinuria
Regulation of the activity of platelet-bound C3 convertase of the alternative pathway of complement by platelet factor H.
Hemoglobinuria, Paroxysmal
Regulation of the activity of platelet-bound C3 convertase of the alternative pathway of complement by platelet factor H.
Hepatitis
Role of fibronectin and complement in immunopathogenesis of acute and subacute hepatic failure.
Hereditary Complement Deficiency Diseases
Serum bactericidal activity against Neisseria meningitidis in patients with C3 nephritic factors is dependent on IgG allotypes.
HIV Infections
Bf S gene frequency in Nigerians with HIV infection.
Hodgkin Disease
Serum levels of ceruloplasmin, properdin factor B and copper in lymphoma patients.
Hypersensitivity
Inactivation of heamolytic complement by house dust allergen in the serum of children with atopic diseases.
Hypertension
The complements and immunoglobulins in different media of healthy pregnant women and in pregnant women with increased blood pressure.
IgA Vasculitis
A study of complement components C3, C5, C6, C7, C8 and C9 in chronic membranoproliferative glomerulonephritis, systemic lupus erythematosus, poststreptococcal nephritis, idiopathic nephrotic syndrome and anaphylactoid purpura.
Infections
Consumptive opsoninopathy: possible pathogenesis in lethal and opportunistic infections.
Infections
Fresh-frozen plasma vs. plasma protein derivative as adjunctive therapy for patients with massive burns.
Infections
Lessons from functional and structural analyses of disease-associated genetic variants in the complement alternative pathway.
Infections
Stringent regulation of complement lectin pathway C3/C5 convertase by C4b-binding protein (C4BP).
Inflammatory Bowel Diseases
The alternate complement pathway in inflammatory bowel disease. Quantitation of the C3 proactivator (factor B) protein.
Influenza, Human
THE QUANTITATIVE DETERMINATION OF INFLUENZA VIRUS AND ANTIBODIES BY MEANS OF RED CELL AGGLUTINATION.
Insulin Resistance
Elevated Properdin and Enhanced Complement Activation in First-Degree Relatives of South Asian Subjects With Type 2 Diabetes.
Kidney Failure, Chronic
Complement gene variants determine the risk of immunoglobulin-associated MPGN and C3 glomerulopathy and predict long-term renal outcome.
Lichen Sclerosus et Atrophicus
HLA antigens and Bf allotypes in lichen sclerosus et atrophicus.
Lipodystrophy
Metabolism of the fifth component of complement, and its relation to metabolism of the third component, in patients with complement activation.
Lipodystrophy
Two types of C3 nephritic factor: properdin-dependent C3NeF and properdin-independent C3NeF.
Liver Cirrhosis
Complement breakdown products in plasma from patients with systemic lupus erythematosus and patients with membranoproliferative or other glomerulonephritis.
Liver Cirrhosis
Complements as new diagnostic tools of hepatocellular carcinoma in cirrhotic patients.
Liver Cirrhosis
[A clinical study of complements as a marker of a hepatocellular carcinoma]
Liver Diseases
Role of serum complement, immunoglobulins, and cell-mediated immune system in the pathogenesis of spontaneous bacterial peritonitis (SBP).
Liver Failure
Role of fibronectin and complement in immunopathogenesis of acute and subacute hepatic failure.
Liver Failure, Acute
Role of fibronectin and complement in immunopathogenesis of acute and subacute hepatic failure.
Lung Injury
Effect of complement fragment 1 esterase inhibition on survival of human decay-accelerating factor pig lungs perfused with human blood.
Lupus Erythematosus, Systemic
A circulating inhibitor of fluid-phase amplification. C3 convertase formation in systemic lupus erythematosus.
Lupus Erythematosus, Systemic
A study of complement components C3, C5, C6, C7, C8 and C9 in chronic membranoproliferative glomerulonephritis, systemic lupus erythematosus, poststreptococcal nephritis, idiopathic nephrotic syndrome and anaphylactoid purpura.
Lupus Erythematosus, Systemic
Dermal-epidermal deposition of complement components and properdin in systemic lupus erythematosus.
Lymphoma
Serum levels of ceruloplasmin, properdin factor B and copper in lymphoma patients.
Lymphoma, Non-Hodgkin
Serum levels of ceruloplasmin, properdin factor B and copper in lymphoma patients.
Malaria, Cerebral
The C5 convertase is not required for activation of the terminal complement pathway in murine experimental cerebral malaria.
Melanoma
Associations of properdin factor B with melanoma.
Melanoma
Characterisation of human malignant melanoma cell lines. VI. Inhibition of 3H-thymidine uptake by normal stimulated lymphocytes.
Melanoma
Induction of immune cytolysis: tumor-cell killing by complement is initiated by covalent complex of monoclonal antibody and stable C3/C5 convertase.
Meningococcal Infections
Serum bactericidal activity against Neisseria meningitidis in patients with C3 nephritic factors is dependent on IgG allotypes.
Multiple Sclerosis
Disease markers in acute multiple sclerosis.
Multiple Sclerosis
HLA-Dw1 and BfF as protective markers in multiple sclerosis.
Multiple Sclerosis
Strong linkage disequilibrium between HLA-Dw2 and and BfS in multiple sclerosis and in the normal population.
Neoplasms
Complement and cancer: activation of the alternative pathway as a theoretical base for immunotherapy.
Neoplasms
Further studies on cytolysis of Ehrlich ascites tumor cells brought into contact with normal human serum. The nature of the heat-labile factor.
Nephritis
A study of complement components C3, C5, C6, C7, C8 and C9 in chronic membranoproliferative glomerulonephritis, systemic lupus erythematosus, poststreptococcal nephritis, idiopathic nephrotic syndrome and anaphylactoid purpura.
Nephritis
Complement breakdown products in plasma from patients with systemic lupus erythematosus and patients with membranoproliferative or other glomerulonephritis.
Nephritis
Hypocomplementemia of membranoproliferative nephritis. Dependence of the nephritic factor reaction on properdin factor B.
Nephritis
Metabolism of the fifth component of complement, and its relation to metabolism of the third component, in patients with complement activation.
Nephritis
The alternative pathway C3 convertase and glomerular deposits.
Nephrotic Syndrome
A study of complement components C3, C5, C6, C7, C8 and C9 in chronic membranoproliferative glomerulonephritis, systemic lupus erythematosus, poststreptococcal nephritis, idiopathic nephrotic syndrome and anaphylactoid purpura.
Nephrotic Syndrome
T-cell subsets and response to mitogens in patients with steroid responsive nephrotic syndrome.
Osteoarthritis
Correlation between levels of breakdown products of C3, C4, and properdin factor B in synovial fluids from patients with rheumatoid arthritis.
Otitis Media
Chronic serous otitis media: an immune complex disease.
Parkinson Disease
HLA-linked complement markers in Alzheimer's and Parkinson's disease: C4 variant (C4B2) a possible marker for senile dementia of the Alzheimer type.
Periodontal Diseases
Gingival fluid and serum in periodontal diseases. II. Evidence for cleavage of complement components C3, C3 proactivator (factor B) and C4 in gingival fluid.
Periodontal Pocket
Gingival fluid and serum in periodontal diseases. II. Evidence for cleavage of complement components C3, C3 proactivator (factor B) and C4 in gingival fluid.
Periodontitis
Association between HLA-A9 and rapidly progressive periodontitis.
Pleural Effusion
High levels of complement breakdown products in tuberculous pleural effusions.
Pleuropneumonia
Role of haemophilus pleuropneumoniae lipopolysaccharide endotoxin in the pathogenesis of porcine Haemophilus pleuropneumonia.
Pneumococcal Infections
Complement system in pneumococcal infections.
Postpartum Thyroiditis
Major histocompatibility complex class II and complement polymorphisms in postpartum thyroiditis.
Pre-Eclampsia
Properdin factor B alleles in pre-eclampsia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Properdin factor B and acute lymphocytic leukemia (ALL).
Psoriasis
Properdin factor B allotypes in Japanese patients with psoriasis.
Sepsis
How immune complexes from certain IgG NAbs and any F(ab')? can mediate excessive complement activation.
Spinocerebellar Degenerations
Hereditary ataxia and the sixth chromosome.
Urogenital Neoplasms
Transferrin, C3 complement, haptoglobin, plasminogen and alpha 2-microglobulin in patients with urogenital tumors.
Virus Diseases
Role of fibronectin and complement in immunopathogenesis of acute and subacute hepatic failure.
Virus Diseases
[Significance of immunocomplexes and complement in renal transplantation. Preliminary data]
Whooping Cough
Oxygen pressure-dependent control of carbonic anhydrase synthesis in chick embryonic erythrocytes.
Xanthomatosis, Cerebrotendinous
Study of a family with Cerebrotendinous Xanthomatosis. No HLA linkage, but an informative recombination between HLA-B and Bf.
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3.4.21.47 alternative-complement-pathway C3/C5 convertase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
