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Information on EC 3.4.17.25 - glutathione-S-conjugate glycine hydrolase

for references in articles please use BRENDA:EC3.4.17.25

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IUBMB Comments

The enzyme participates in a glutathione-mediated detoxification pathway found in plants, algae, fungi, and some bacteria. The enzymes from the plant Arabidopsis thaliana and the yeast Saccharomyces cerevisiae also catalyse the activity of EC 2.3.2.15, glutathione γ-glutamylcysteinyltransferase (phytochelatin synthase).

The enzyme appears in viruses and cellular organisms

Synonyms
alr0975, ATG42, CPC, PCS1, PRC1, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a glutathione-S-conjugate + H2O = a [gamma-glutamyl-L-cysteine]-S-conjugate + glycine
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
glutathione-mediated detoxification II, indole glucosinolate activation (intact plant cell)
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