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Information on EC 3.2.2.25 - N-methyl nucleosidase

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EC Tree
     3 Hydrolases
         3.2 Glycosylases
             3.2.2 Hydrolysing N-glycosyl compounds
                3.2.2.25 N-methyl nucleosidase
IUBMB Comments
The enzyme preferentially hydrolyses 3- and 7-methylpurine nucleosides, such as 3-methylxanthosine, 3-methyladenosine and 7-methylguanosine. Hydrolysis of 7-methylxanthosine to form 7-methylxanthine is the second step in the caffeine-biosynthesis pathway.
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The enzyme appears in viruses and cellular organisms
Synonyms
7-methyl-N9-nucleoside hydrolase, N-MeNase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
7-methylxanthosine + H2O = 7-methylxanthine + D-ribose
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