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Information on EC 3.2.1.52 - beta-N-acetylhexosaminidase and Organism(s) Coccidioides posadasii and UniProt Accession E9DFH0

for references in articles please use BRENDA:EC3.2.1.52
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EC Tree
IUBMB Comments
Acts on N-acetylglucosides and N-acetylgalactosides.
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Select one or more organisms in this record: ?
This record set is specific for:
Coccidioides posadasii
UNIPROT: E9DFH0
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Word Map
The taxonomic range for the selected organisms is: Coccidioides posadasii
The enzyme appears in selected viruses and cellular organisms
Synonyms
beta-hexosaminidase, hexosaminidase, n-acetyl-beta-glucosaminidase, o-glcnacase, hex a, n-acetylglucosaminidase, hexosaminidase a, beta-n-acetylhexosaminidase, hex b, beta-hexosaminidase a, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
chitobiase
Q309C3
-
2-acetamido-2-deoxy-beta-D-glucoside acetamidodeoxyglucohydrolase
-
-
-
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65 kDa epididymal boar protein
-
-
-
-
beta-acetylaminodeoxyhexosidase
-
-
-
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beta-acetylhexosaminidase
-
-
-
-
beta-acetylhexosaminidinase
-
-
-
-
beta-D-hexosaminidase
-
-
-
-
beta-D-N-acetylhexosaminidase
-
-
-
-
Beta-GlcNAcase
-
-
-
-
beta-hexosaminidase
-
-
-
-
beta-N-acetyl-D-hexosaminidase
-
-
-
-
beta-N-acetyl-hexosaminidase
-
-
-
-
beta-N-acetylgalactosaminidase
-
-
-
-
beta-N-acetylglucosaminidase
-
-
-
-
Beta-N-acetylhexosaminidase
-
-
-
-
beta-NAHA
-
-
-
-
Beta-NAHASE
-
-
-
-
chitobiase
-
-
-
-
Hex
-
-
-
-
hexosaminidase
-
-
-
-
hexosaminidase A
-
-
-
-
N-acetyl-beta-D-hexosaminidase
-
-
-
-
N-acetyl-beta-glucosaminidase
-
-
-
-
N-acetyl-beta-hexosaminidase
-
-
-
-
N-acetylhexosaminidase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
O-glycosyl bond hydrolysis
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
beta-N-acetyl-D-hexosaminide N-acetylhexosaminohydrolase
Acts on N-acetylglucosides and N-acetylgalactosides.
CAS REGISTRY NUMBER
COMMENTARY hide
9012-33-3
c.f. EC 3.2.1.165
9027-52-5
deleted
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
4-methylumbelliferyl N,N',N''-triacetyl-beta-D-chitotrioside + 3 H2O
4-methylumbelliferone + 3 N-acetylglucosamine
show the reaction diagram
A7XUU4, Q309C3
-
-
-
?
4-methylumbelliferyl N,N'-diacetyl-beta-D-chitobioside + 2 H2O
4-methylumbelliferone + 2 N-acetylgalactosamine
show the reaction diagram
A7XUU4, Q309C3
-
-
-
?
4-methylumbelliferyl N-acetyl-beta-D-galactosamine + H2O
4-methylumbelliferone + N-acetylgalactosamine
show the reaction diagram
A7XUU4, Q309C3
-
-
-
?
4-methylumbelliferyl N-acetyl-beta-D-glucosamine + H2O
4-methylumbelliferone + N-acetylglucosamine
show the reaction diagram
A7XUU4, Q309C3
-
-
-
?
4-methylumbelliferyl N,N',N''-triacetyl-beta-D-chitotrioside + 3 H2O
4-methylumbelliferone + 3 N-acetylglucosamine
show the reaction diagram
A7XUU4, Q309C3
-
-
-
?
4-methylumbelliferyl N,N'-diacetyl-beta-D-chitobioside + 2 H2O
4-methylumbelliferone + 2 N-acetylgalactosamine
show the reaction diagram
A7XUU4, Q309C3
-
-
-
?
4-methylumbelliferyl N-acetyl-beta-D-galactosamine + H2O
4-methylumbelliferone + N-acetylgalactosamine
show the reaction diagram
A7XUU4, Q309C3
-
-
-
?
4-methylumbelliferyl N-acetyl-beta-D-glucosamine + H2O
4-methylumbelliferone + N-acetylglucosamine
show the reaction diagram
A7XUU4, Q309C3
-
-
-
?
additional information
?
-
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
A7XUU4, Q309C3
cells in SE phase
Manually annotated by BRENDA team
A7XUU4, Q309C3
cells in SE phase
Manually annotated by BRENDA team
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
68500
A7XUU4, Q309C3
x * 68500, about, SDS-PAGE and amino acid sequence calculation
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
?
A7XUU4, Q309C3
x * 68500, about, SDS-PAGE and amino acid sequence calculation
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
native Hex1 from SE cells partly by ammonium sulfate fractionation, recombinant His-tagged enzyme from Escherichia coli by nickel affinity chromatography
A7XUU4, Q309C3
native Hex2 from SE cells partly by ammonium sulfate fractionation, recombinant His-tagged enzyme from Escherichia coli by nickel affinity chromatography
A7XUU4, Q309C3
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene CpHEX1, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression in Escherichia coli strain BL21
A7XUU4, Q309C3
gene CpHEX2, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression in Escherichia coli strain BL21
A7XUU4, Q309C3
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lunetta, J.M.; Johnson, S.M.; Pappagianis, D.
Molecular cloning, characterization and expression analysis of two beta-N-acetylhexosaminidase homologs of Coccidioides posadasii
Med. Mycol.
48
744-756
2010
Coccidioides posadasii (A7XUU4), Coccidioides posadasii (Q309C3), Coccidioides posadasii, Coccidioides posadasii Silveira (A7XUU4), Coccidioides posadasii Silveira (Q309C3)
Manually annotated by BRENDA team