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Information on EC 3.1.7.10 - (13E)-labda-7,13-dien-15-ol synthase and Organism(s) Selaginella moellendorffii and UniProt Accession G1DGI7

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.7 Diphosphoric-monoester hydrolases
                3.1.7.10 (13E)-labda-7,13-dien-15-ol synthase
IUBMB Comments
The enzyme from the lycophyte Selaginella moellendorffii is bifunctional, initially forming (13E)-labda-7,13-dien-15-yl diphosphate, which is hydrolysed to the alcohol.
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This record set is specific for:
Selaginella moellendorffii
UNIPROT: G1DGI7
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The taxonomic range for the selected organisms is: Selaginella moellendorffii
The enzyme appears in selected viruses and cellular organisms
Synonyms
CPSKSL1, labda-7,13E-dien-15-ol-producing bifunctional diterpene synthase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
labda-7,13E-dien-15-ol-producing bifunctional diterpene synthase
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SYSTEMATIC NAME
IUBMB Comments
geranylgeranyl-diphosphate diphosphohydrolase [(13E)-labda-7,13-dien-15-ol-forming]
The enzyme from the lycophyte Selaginella moellendorffii is bifunctional, initially forming (13E)-labda-7,13-dien-15-yl diphosphate, which is hydrolysed to the alcohol.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
geranylgeranyl diphosphate + H2O
(13E)-labda-7,13-dien-15-ol + diphosphate
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-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
TPS7_SELML
750
0
86619
Swiss-Prot
other Location (Reliability: 2)
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
Ni-NTA resin column chromatography
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli C41 cells
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Mafu, S.; Hillwig, M.; Peters, R.
A novel labda-7,13E-dien-15-ol-producing bifunctional diterpene synthase from Selaginella moellendorffii
ChemBioChem
12
1984-1987
2011
Selaginella moellendorffii (G1DGI7), Selaginella moellendorffii
Manually annotated by BRENDA team