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Information on EC 3.1.3.57 - inositol-1,4-bisphosphate 1-phosphatase and Organism(s) Arabidopsis thaliana and UniProt Accession Q42546

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.3 Phosphoric-monoester hydrolases
                3.1.3.57 inositol-1,4-bisphosphate 1-phosphatase
IUBMB Comments
The enzyme acts on inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate (forming inositol 3,4-bisphosphate) with similar Vmax values for both substrates, but with a five-times higher affinity for the bisphosphate. Does not act on inositol 1-phosphate, inositol 1,4,5-trisphosphate or inositol 1,3,4,5-tetrakisphosphate.
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This record set is specific for:
Arabidopsis thaliana
UNIPROT: Q42546
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
inositol polyphosphate 1-phosphatase, inositol polyphosphate-1-phosphatase, rnpip, inositol-1,4-bisphosphate 1-phosphatase, inositol-polyphosphate 1-phosphatase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
inositol polyphosphate-1-phosphatase
dual enzymatic activity: 3'(2'),5'-bisphosphate nucleosidase, gene FRY1, FIERY1
inositol-polyphosphate 1-phosphatase
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INPP
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IPP
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IPPase
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phosphatase, inositol 1,4-bisphosphate 1-
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RnPIP
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of phosphoric ester
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
1D-myo-inositol-1,4-bisphosphate 1-phosphohydrolase
The enzyme acts on inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate (forming inositol 3,4-bisphosphate) with similar Vmax values for both substrates, but with a five-times higher affinity for the bisphosphate. Does not act on inositol 1-phosphate, inositol 1,4,5-trisphosphate or inositol 1,3,4,5-tetrakisphosphate.
CAS REGISTRY NUMBER
COMMENTARY hide
111070-17-8
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
additional information
?
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involved in stress signal transduction and abscisic acid signaling
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-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
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involved in stress signal transduction and abscisic acid signaling
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-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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SwissProt
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
DPNP1_ARATH
353
0
37564
Swiss-Prot
other Location (Reliability: 4)
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
for genetic complementation
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Xiong, L.; Lee, B.; Ishitani, M.; Lee, H.; Zhang, C.; Zhu, J.K.
FIERY1 encoding an inositol polyphosphate 1-phosphatase is a negative regulator of abscisic acid and stress signaling in Arabidopsis
Genes Dev.
15
1971-1984
2001
Arabidopsis thaliana
Manually annotated by BRENDA team
Kim, B.H.; von Arnim, A.G.
FIERY1 regulates light-mediated repression of cell elongation and flowering time via its 3(2),5-bisphosphate nucleotidase activity
Plant J.
58
208-219
2009
Arabidopsis thaliana (Q42546)
Manually annotated by BRENDA team