Information on EC 3.1.1.21 - retinyl-palmitate esterase

for references in articles please use BRENDA:EC3.1.1.21
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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
3.1.1.21
deleted, Now known to be catalysed by EC 3.1.1.1, carboxylesterase and EC 3.1.1.3, triacylglycerol lipase
RECOMMENDED NAME
GeneOntology No.
retinyl-palmitate esterase
-
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
physiological function
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hormone-sensitive lipase displays prominent REH activity. Importance of hormone-sensitive lipase as a REH of adipose tissue, hormone-sensitive lipase via this action provides retinoic acid and other retinoids for signaling events that are crucial for adipocyte differentiation and lineage commitment. REH activity in visceral white adipose tissue of hormone-sensitive lipase-null mice is completely blunted and accompanied by increased levels of retinyl esters and decreased levels of retinol, retinaldehyde and all-trans retinoic acid. REH activity is also reduced in brown adipose tissue of hormone-sensitive lipase-null mice