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Information on EC 2.7.7.80 - molybdopterin-synthase adenylyltransferase

for references in articles please use BRENDA:EC2.7.7.80

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IUBMB Comments

Adenylates the C-terminus of the small subunit of the molybdopterin synthase. This activation is required to form the thiocarboxylated C-terminus of the active molybdopterin synthase small subunit. The reaction occurs in prokaryotes and eukaryotes. In the human, the reaction is catalysed by the N-terminal domain of the protein MOCS3, which also includes a molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) C-terminal domain.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea

Synonyms
mocs3, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate + [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
molybdopterin biosynthesis
Highest Expressing Human Cell Lines
Cell Line Links Gene Links