Information on EC 184.108.40.206 - tau-protein kinase and Organism(s) Schizosaccharomyces pombe and UniProt Accession Q10452for references in articles please use BRENDA:EC220.127.116.11
Word Map on EC 18.104.22.168
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The taxonomic range for the selected organisms is: Schizosaccharomyces pombe
The enzyme appears in selected viruses and cellular organisms
phospho group transfer
Activated by tubulin. Involved in the formation of paired helical filaments, which are the main fibrous component of all fibrillary lesions in brain and are associated with Alzheimer's disease.
autophosphorylation, phosphorylation on a conserved tyrosine residue is required for efficient activity. Phosphorylated at a Ser225 is likely to inhibit its function