Information on EC 2.7.11.26 - tau-protein kinase and Organism(s) Schizosaccharomyces pombe and UniProt Accession Q10452

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Schizosaccharomyces pombe
UNIPROT: Q10452
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The taxonomic range for the selected organisms is: Schizosaccharomyces pombe

The enzyme appears in selected viruses and cellular organisms

EC NUMBER
COMMENTARY hide
2.7.11.26
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RECOMMENDED NAME
GeneOntology No.
tau-protein kinase
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
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SYSTEMATIC NAME
IUBMB Comments
ATP:[tau-protein] O-phosphotransferase
Activated by tubulin. Involved in the formation of paired helical filaments, which are the main fibrous component of all fibrillary lesions in brain and are associated with Alzheimer's disease.
CAS REGISTRY NUMBER
COMMENTARY hide
111694-09-8
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
POSTTRANSLATIONAL MODIFICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phosphoprotein
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autophosphorylation, phosphorylation on a conserved tyrosine residue is required for efficient activity. Phosphorylated at a Ser225 is likely to inhibit its function
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE