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IUBMB CommentsThe enzyme, characterized from the bacterium Mycobacterium smegmatis, participates in the degradation of L-threitol.
The enzyme appears in viruses and cellular organisms
Synonyms
L-erythrulose 4-kinase,
lerK,
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L-erythrulose 4-kinase
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ATP + L-erythrulose = ADP + L-erythrulose 1-phosphate
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ATP:L-erythrulose 1-phosphotransferase
The enzyme, characterized from the bacterium Mycobacterium smegmatis, participates in the degradation of L-threitol.
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ATP + D-erythrulose
ADP + D-erythrulose 4-phosphate
catalytic efficiency is 4fold lower compared to L-erythrulose as substrate
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ATP + dihydroxyacetone
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catalytic efficiency is about 100fold lower compared to L-erythrulose as substrate
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ATP + L-erythrulose
ADP + L-erythrulose 4-phosphate
ATP + L-erythrulose
ADP + L-erythrulose 4-phosphate
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ATP + L-erythrulose
ADP + L-erythrulose 4-phosphate
the enzyme participates in the degradation of L-threitol
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ATP + L-erythrulose
ADP + L-erythrulose 4-phosphate
the enzyme participates in the degradation of L-threitol
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0.0106
D-erythrulose
pH and temperature not specified in the publication
0.0378
dihydroxyacetone
pH and temperature not specified in the publication
0.003
L-erythrulose
pH and temperature not specified in the publication
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1.6
D-erythrulose
pH and temperature not specified in the publication
2.12
dihydroxyacetone
pH and temperature not specified in the publication
1.79
L-erythrulose
pH and temperature not specified in the publication
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150.9
D-erythrulose
pH and temperature not specified in the publication
56.1
dihydroxyacetone
pH and temperature not specified in the publication
597
L-erythrulose
pH and temperature not specified in the publication
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SwissProt
brenda
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metabolism
the enzyme participates in the degradation of L-threitol
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LERK_MYCS2
Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
571
0
59357
Swiss-Prot
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LERK_PECAS
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
590
0
61435
Swiss-Prot
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A0A3Q9J256_9MICO
584
0
59065
TrEMBL
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A0A653QEX3_9GAMM
581
0
60214
TrEMBL
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A0A653QGD7_9MICO
594
0
60115
TrEMBL
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A0A653LNK2_9MICO
589
0
60836
TrEMBL
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A0A3S9WGS9_9MICO
566
0
58650
TrEMBL
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A0A344UVN8_9ACTN
566
0
57754
TrEMBL
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A0A653NTA3_9MICC
585
0
59393
TrEMBL
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A0A653VT32_9GAMM
576
0
59949
TrEMBL
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A0A3Q9J2X7_9MICO
576
0
57973
TrEMBL
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A0A653VQ31_9MICC
584
0
59694
TrEMBL
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A0A645AS19_9ZZZZ
342
0
37277
TrEMBL
other Location (Reliability: 1)
A0A6N7CIA8_9NOCA
577
0
59732
TrEMBL
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Huang, H.; Carter, M.S.; Vetting, M.W.; Al-Obaidi, N.; Patskovsky, Y.; Almo, S.C.; Gerlt, J.A.
A general strategy for the discovery of metabolic pathways: D-threitol, L-threitol, and erythritol utilization in Mycobacterium smegmatis
J. Am. Chem. Soc.
137
14570-14573
2015
Mycolicibacterium smegmatis (A0R758)
brenda
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