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Information on EC 2.5.1.141 - heme o synthase and Organism(s) Cereibacter sphaeroides and UniProt Accession Q3J5F9

for references in articles please use BRENDA:EC2.5.1.141
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IUBMB Comments
The enzyme, found in many archaea, bacteria, and eukaryotes, produces heme o, which in many cases is further modified into heme a. In organisms that produce heme a, the enzyme forms a complex with heme a synthase. In some archaeal species the enzyme transfers a geranylgeranyl group instead of a farnesyl group.
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This record set is specific for:
Cereibacter sphaeroides
UNIPROT: Q3J5F9
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The taxonomic range for the selected organisms is: Cereibacter sphaeroides
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
cox10, heme o synthase, heme a:farnesyltransferase, protoheme ix farnesyltransferase, cyoe protein, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
protoheme IX farnesyltransferase
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SYSTEMATIC NAME
IUBMB Comments
(2E,6E)-farnesyl-diphosphate:protoheme IX farnesyltranstransferase
The enzyme, found in many archaea, bacteria, and eukaryotes, produces heme o, which in many cases is further modified into heme a. In organisms that produce heme a, the enzyme forms a complex with heme a synthase. In some archaeal species the enzyme transfers a geranylgeranyl group instead of a farnesyl group.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed of 6 * His epitope-tagged enzyme in Escherichia coli
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Brown, B.M.; Wang, Z.; Brown, K.R.; Cricco, J.A.; Hegg, E.L.
Heme O synthase and heme A synthase from Bacillus subtilis and Rhodobacter sphaeroides interact in Escherichia coli
Biochemistry
43
13541-13548
2004
Bacillus subtilis (P24009), Bacillus subtilis, Bacillus subtilis 168 (P24009), Cereibacter sphaeroides (Q3J5F9), Cereibacter sphaeroides, Cereibacter sphaeroides DSM 158 (Q3J5F9)
Manually annotated by BRENDA team