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Information on EC 2.4.2.26 - protein xylosyltransferase and Organism(s) Caenorhabditis elegans and UniProt Accession Q965Q8

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.26 protein xylosyltransferase
IUBMB Comments
Involved in the biosynthesis of the linkage region of glycosaminoglycan chains as part of proteoglycan biosynthesis (chondroitin, dermatan and heparan sulfates).
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This record set is specific for:
Caenorhabditis elegans
UNIPROT: Q965Q8
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Word Map
The taxonomic range for the selected organisms is: Caenorhabditis elegans
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
xylt2, xt-ii, xylt-ii, xylosyltransferase 1, xylt-i, xylosyltransferase ii, xylosyltransferase 2, protein xylosyltransferase, peptide o-xylosyltransferase, sqv-6, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
peptide O-xylosyltransferase
-
squashed vulva protein 6
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UDP-alpha-D-xylose:proteoglycan core protein beta-D-xylosyltransferase
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xylosyltransferase sqv-6
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UDP-D-xylose:core protein beta-D-xylosyltransferase
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-
-
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UDP-D-xylose:core protein xylosyltransferase
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-
-
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UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase
-
-
-
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UDP-xylose-core protein beta-D-xylosyltransferase
-
-
-
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uridine diphosphoxylose-core protein beta-xylosyltransferase
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-
-
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uridine diphosphoxylose-protein xylosyltransferase
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-
-
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xylosyltransferase, uridine diphosphoxylose-core protein beta-
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pentosyl group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
UDP-alpha-D-xylose:protein beta-D-xylosyltransferase (configuration-inverting)
Involved in the biosynthesis of the linkage region of glycosaminoglycan chains as part of proteoglycan biosynthesis (chondroitin, dermatan and heparan sulfates).
CAS REGISTRY NUMBER
COMMENTARY hide
55576-38-0
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
UDP-D-xylose + DDDSIEGSGSGGR
UDP + DDD-(D-xylosyl)SIEGSGSGGR
show the reaction diagram
-
-
-
?
UDP-D-xylose + QEEEGSGGGGQR
UDP + QEEEG(-D-xylosyl)SGGGGQR
show the reaction diagram
-
-
-
?
UDP-D-xylose + SIEGSGGR
UDP + (D-xylosyl)SIEGSGGR
show the reaction diagram
-
-
-
?
additional information
?
-
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
XYLT_CAEEL
806
1
93115
Swiss-Prot
Secretory Pathway (Reliability: 2)
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Pichia pastoris
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Brunner, A.; Kolarich, D.; Voglmeir, J.; Paschinger, K.; Wilson, I.B.
Comparative characterisation of recombinant invertebrate and vertebrate peptide O-xylosyltransferases
Glycoconj. J.
23
543-554
2006
Caenorhabditis elegans (Q965Q8), Caenorhabditis elegans, Drosophila melanogaster, Homo sapiens (Q86Y38), Homo sapiens
Manually annotated by BRENDA team