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UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-(2Z,6Z)-farnesol
UDP + beta-D-galactofuranosyl-(1-4)-alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-(2Z,6Z)-farnesol
UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octacis-decaprenol
UDP + beta-D-galactofuranosyl-(1-4)-alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octacis-decaprenol
UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
UDP + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
additional information
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UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-(2Z,6Z)-farnesol
UDP + beta-D-galactofuranosyl-(1-4)-alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-(2Z,6Z)-farnesol
synthetic substrate surrogate. Substitution of the farnesol group to isoprenol reduces activity by about 75%
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UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-(2Z,6Z)-farnesol
UDP + beta-D-galactofuranosyl-(1-4)-alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-(2Z,6Z)-farnesol
synthetic substrate surrogate. Substitution of the farnesol group to isoprenol reduces activity by about 75%
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UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octacis-decaprenol
UDP + beta-D-galactofuranosyl-(1-4)-alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octacis-decaprenol
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UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octacis-decaprenol
UDP + beta-D-galactofuranosyl-(1-4)-alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octacis-decaprenol
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UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
UDP + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
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UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
UDP + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
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UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
UDP + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
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the bifunctional enzyme is responsible for the initial synthesis of C50-P-P-GlcNAc-Rha-Galf, followed by immediate conversion to C50-P-P-GlcNAc-Rha-Galf-Galf
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enzyme requires a substrate bearing the disaccharide L-Rha-alpha-(1,3)-D-GlcNAc. Phosphonophosphate analogues serve as effective substrates, being processed to lipid-linked oligosaccharides
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additional information
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enzyme requires a substrate bearing the disaccharide L-Rha-alpha-(1,3)-D-GlcNAc. Phosphonophosphate analogues serve as effective substrates, being processed to lipid-linked oligosaccharides
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additional information
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the bifunctional enzyme is responsible for the initial synthesis of C50-P-P-GlcNAc-Rha-Galf, followed by immediate conversion to C50-P-P-GlcNAc-Rha-Galf-Galf
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additional information
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the enzyme harbors dual beta-(1->4) and beta-(1->5) galactofuranose transferase activities. The enzyme cannot catalyze subsequent galactan chain extension. Gal-Gal-Gal-Rha-GlcNAc-P-P-decaprenol is not a substrate
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Atherosclerosis
Galactosyl transferase assay. Application to experimental atherosclerosis.
Brain Diseases
Biochemical changes in Cuprizone-induced spongiform encephalopathy. I. Changes in the activities of 2',3'-cyclic nucleotide 3'-phosphohydrolase, oligodendroglial ceramide galactosyl transferase, and the hydrolysis of the alkenyl group of alkenyl, acyl-glycerophospholipids by plasmalogenase in different regions of the brain.
Breast Neoplasms
Gene expression of ceramide kinase, galactosyl ceramide synthase and ganglioside GD3 synthase is associated with prognosis in breast cancer.
Carcinogenesis
Galactosyl transferase activity in rat bladder transitional cell carcinoma lines and in exfoliated cells in urine during carcinogenesis and reversible hyperplasia.
Carcinoma
Correlation between tumour size, metastatic spread and galactosyl transferase activity in cyclophosphamide-treated mice bearing the Lewis lung carcinoma.
Carcinoma
Galactosyl transferase activity in human transitional cell carcinoma lines and in benign and neoplastic human bladder epithelium.
Carcinoma
Galactosyl transferase activity in rat bladder transitional cell carcinoma lines and in exfoliated cells in urine during carcinogenesis and reversible hyperplasia.
Carcinoma, Ehrlich Tumor
Glycoprotein biosynthesis: purification and characterization of a glycoprotein: galactosyl transferase from Ehrlich ascites tumor cell membranes.
Carcinoma, Hepatocellular
[Recent advances in laboratory tests for liver diseases]
Carcinoma, Lewis Lung
Correlation between tumour size, metastatic spread and galactosyl transferase activity in cyclophosphamide-treated mice bearing the Lewis lung carcinoma.
Carcinoma, Transitional Cell
Galactosyl transferase activity in human transitional cell carcinoma lines and in benign and neoplastic human bladder epithelium.
Carcinoma, Transitional Cell
Galactosyl transferase activity in rat bladder transitional cell carcinoma lines and in exfoliated cells in urine during carcinogenesis and reversible hyperplasia.
Colonic Neoplasms
[Blood serum galactosyltransferase in oncologic diseases]
Cystic Fibrosis
Enhanced UDP-galactose:glycoprotein galactosyl transferase activity in cultivated skin fibroblasts from patients with cystic fibrosis and its possible relationship to the pathogenesis of the disease.
Demyelinating Diseases
Cerebroside synthesis as a measure of the rate of remyelination following cuprizone-induced demyelination in brain.
Ehlers-Danlos Syndrome
Glycan profiling of a defect in decorin glycosylation in equine systemic proteoglycan accumulation, a potential model of progeroid form of Ehlers-Danlos syndrome.
Galactosemias
The molecular relationship between deficient UDP-galactose uridyl transferase (GALT) and ceramide galactosyltransferase (CGT) enzyme function: a possible cause for poor long-term prognosis in classic galactosemia.
Glioma
Increased myelination related enzymatic activities in neuron-glial heterokarya.
Herpes Simplex
Altered kinetic properties of sialyl and galactosyl transferases associated with herpes simplex virus infection of GMK and BHK cells.
Herpes Zoster
Molecular aspects of mammalian fertilization.
Hyperprolactinemia
Role of prolactin on epididymal glycoprotein metabolism in matured monkeys, Macaca radiata: specific activities of glycosyltransferases and glycosidases.
Infections
The specificity of serum uridine 5'-phosphogalactose: glycoprotein galactosyl transferase activity in the diagnosis of ovarian cancer.
Malaria
Association of malaria with inactivation of alpha1,3-galactosyl transferase in catarrhines.
Multiple Sclerosis
Are the decrease in circulating anti-?1,3-Gal IgG and the lower content of galactosyl transferase A1 in the microbiota of patients with multiple sclerosis a novel environmental risk factor for the disease?
Neoplasms
Correlation between tumour size, metastatic spread and galactosyl transferase activity in cyclophosphamide-treated mice bearing the Lewis lung carcinoma.
Neoplasms
Exosomes Secreted by Adipose-Derived Mesenchymal Stem Cells Foster Metastasis and Osteosarcoma Proliferation by Increasing COLGALT2 Expression.
Neoplasms
Gene expression of ceramide kinase, galactosyl ceramide synthase and ganglioside GD3 synthase is associated with prognosis in breast cancer.
Neoplasms
Glycoprotein biosynthesis: purification and characterization of a glycoprotein: galactosyl transferase from Ehrlich ascites tumor cell membranes.
Neoplasms
Serum galactosyl transferase levels in patients with advanced cancer.
Neoplasms
The specificity of serum uridine 5'-phosphogalactose: glycoprotein galactosyl transferase activity in the diagnosis of ovarian cancer.
Neoplasms
Tumor necrosis factor alpha induces endothelial galactosyl transferase activity and verocytotoxin receptors. Role of specific tumor necrosis factor receptors and protein kinase C.
Neoplasms
[A galactosyl transferase isoenzyme as a tumor specific diagnostic aid]
Neoplasms
[Blood serum galactosyltransferase in oncologic diseases]
Neoplasms
[Possible markers of the progression and ulcerogenesis of stomach cancer]
Neoplasms
[Preparative isolation of human galactosyltransferase. A comparison of methods]
Neuroblastoma
Increased myelination related enzymatic activities in neuron-glial heterokarya.
Ovarian Neoplasms
The specificity of serum uridine 5'-phosphogalactose: glycoprotein galactosyl transferase activity in the diagnosis of ovarian cancer.
Ovarian Neoplasms
[Blood serum galactosyltransferase in oncologic diseases]
Ovarian Neoplasms
[Preparative isolation of human galactosyltransferase. A comparison of methods]
Ovarian Neoplasms
[The usefulness and limitation of sugar antigen in ovarian cancers--with special reference to a new tumor marker, CA54/61]
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Blood serum galactosyltransferase in oncologic diseases]
Stomach Neoplasms
[Possible markers of the progression and ulcerogenesis of stomach cancer]
Thrombosis
Life-supporting function of genetically modified swine lungs in baboons.
Thrombosis
Uridine 5'-diphosphate galactose: glycoprotein galactosyl transferase activity in exfoliated bladder epithelial cells in rats fed N-(4-(5-nitro-2-furyl)-2-thiazolyl) formamide.
Tuberculosis
Biosynthesis of Galactan in Mycobacterium tuberculosis as a Viable TB Drug Target?
Tuberculosis
Expression, purification and characterisation of soluble GlfT and the identification of a novel galactofuranosyltransferase Rv3782 involved in priming GlfT-mediated galactan polymerisation in Mycobacterium tuberculosis.
Tuberculosis
Galactosyl transferases in mycobacterial cell wall synthesis.
Tuberculosis
Identification of a novel galactosyl transferase involved in biosynthesis of the mycobacterial cell wall.
Vitamin A Deficiency
Vitamin A and galactosyl transferase of tracheal epithelium.
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Mikusova, K.; Belanova, M.; Kordulakova, J.; Honda, K.; McNeil, M.; Mahapatra, S.; Crick, D.; Brennan, P.
Identification of a novel galactosyl transferase involved in biosynthesis of the mycobacterial cell wall
J. Bacteriol.
188
6592-6598
2006
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
brenda
Belanova, M.; Dianiskova, P.; Brennan, P.J.; Completo, G.C.; Rose, N.L.; Lowary, T.L.; Mikusova, K.
Galactosyl transferases in mycobacterial cell wall synthesis
J. Bacteriol.
190
1141-1145
2008
Mycolicibacterium smegmatis
brenda
Martinez Farias, M.A.; Kincaid, V.A.; Annamalai, V.R.; Kiessling, L.L.
Isoprenoid phosphonophosphates as glycosyltransferase acceptor substrates
J. Am. Chem. Soc.
136
8492-8495
2014
Mycobacterium tuberculosis (P9WMX3), Mycobacterium tuberculosis ATCC 25618 (P9WMX3)
brenda
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2.4.1.287 rhamnopyranosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,4/1,5-galactofuranosyltransferase
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