Information on EC 2.4.1.199 - beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase

for references in articles please use BRENDA:EC2.4.1.199
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The expected taxonomic range for this enzyme is: Mycobacterium smegmatis

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EC NUMBER
COMMENTARY hide
2.4.1.199
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RECOMMENDED NAME
GeneOntology No.
beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
beta-D-mannosylphosphodecaprenol + (1->6)-alpha-D-mannosyloligosaccharide = decaprenol phosphate + (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-oligosaccharide
show the reaction diagram
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-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hexosyl group transfer
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-
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SYSTEMATIC NAME
IUBMB Comments
beta-D-mannosylphosphodecaprenol:(1->6)-alpha-D-mannosyloligosaccharide 6-alpha-D-mannosyltransferase
Involved in the formation of mannooligosaccharides in the membrane of Mycobacterium smegmatis.
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CAS REGISTRY NUMBER
COMMENTARY hide
125008-27-7
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
mannosylphosphodecaprenol + 1,6-alpha-D-mannooligosaccharides
decaprenol phosphate + 1,6-alpha-D-mannosyl-1,6-alpha-D-mannooligosaccharides
show the reaction diagram
mannosylphosphodecaprenol + 1,6-alpha-D-mannopentaose
decaprenol phosphate + 1,6-alpha-D-mannohexaose
show the reaction diagram
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-
-
-
?
mannosylphosphodecaprenol + 1,6-alpha-D-mannotetraose
decaprenol phosphate + 1,6-alpha-D-mannosylpentaose
show the reaction diagram
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-
-
-
?
mannosylphosphodecaprenol + 1,6-alpha-D-mannotriose
decaprenol phosphate + 1,6-alpha-D-mannosyltetraose
show the reaction diagram
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-
-
-
?
mannosylphosphodecaprenol + methyl-alpha-D-mannoside
decaprenol phosphate + ?
show the reaction diagram
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-
-
-
?
mannosylphosphodecaprenol + myo-inositol-trimannoside
decaprenol phosphate + ?
show the reaction diagram
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with an 1,6-alpha-mannobiose unit as part of its structure
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-
?
additional information
?
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substrate specificity
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
mannosylphosphodecaprenol + 1,6-alpha-D-mannooligosaccharides
decaprenol phosphate + 1,6-alpha-D-mannosyl-1,6-alpha-D-mannooligosaccharides
show the reaction diagram
-
involved in the formation of mannooligosaccharides in membrane of Mycobacterium smegmatis
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-
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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2.6
1,6-alpha-D-mannopentaose
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2.4
1,6-alpha-D-mannotetraose
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2
1,6-alpha-D-mannotriose
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-
35.7
1,6-alpha-mannobiose
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-
86.9
mannose
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-
28.6
methyl-alpha-D-mannoside
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-
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
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-
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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
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TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
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LINKS TO OTHER DATABASES (specific for EC-Number 2.4.1.199)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
InterPro (database of protein families, domains and functional sites)