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Information on EC 2.4.1.152 - 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase and Organism(s) Takifugu rubripes and UniProt Accession Q70AH4

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EC Tree
IUBMB Comments
Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. This enzyme fucosylates on O-3 of an N-acetylglucosamine that carries a galactosyl group on O-4, unlike EC 2.4.1.65, 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase, which fucosylates on O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3.
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This record set is specific for:
Takifugu rubripes
UNIPROT: Q70AH4
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Word Map
The taxonomic range for the selected organisms is: Takifugu rubripes
The enzyme appears in selected viruses and cellular organisms
Synonyms
fuc-tv, alpha-3-fucosyltransferase, fucosyltransferase 4, alpha-3-l-fucosyltransferase, fut vi, alpha1,3 fuct-vii, alpha1,3ft, alpha1,3-fuct, fuctvii, fucosyltransferase-vii, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
alpha3-fucosyltransferase
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alpha(1-3)fucosyltransferase
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-
-
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alpha-(1,3)-fucosyltransferase
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alpha-3-fucosyltransferase
-
-
-
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alpha-3-L-fucosyltransferase
-
-
-
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alpha1,3 fucosyltransferase
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-
-
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alpha1,3FT
-
-
-
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alpha1-3 fucosyltransferase
-
-
-
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alpha1->3fucosyltransferase
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-
-
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alpha3-fucosyltransferase
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alpha3-fucosyltransferase-V
-
-
-
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alpha3-fucosyltransferase-VI
-
-
-
-
Fuc-Tb
-
-
-
-
Fuc-TV
-
-
-
-
fucosyltransferase 11
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fucosyltransferase, guanosine diphosphofucose-glucoside alpha1-->3-
-
-
-
-
FucT-VI
-
-
-
-
FUT5
-
-
-
-
FUT6
-
-
-
-
galactoside 3-fucosyltransferase
-
-
-
-
galactoside 3-L-fucosyltransferase 11
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GDL-L-fucose:N-acetyl-beta-D-glucosaminyl alpha-3-L-fucosyltransferase
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-
-
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GDP-Fuc:Galbeta1-4GlcNAc (Fuc to GlcNAc) alpha1-3 fucosyltransferase
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-
-
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GDP-fucose:beta-D-N-acetylglucosaminide 3-alpha-fucosyltransferase
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-
-
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GDP-fucose:Galbeta(1-4)GlcNAc-R alpha(1-3)fucosyltransferase
-
-
-
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GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-galactosaminyl-R 3-L-fucosyltransferase
-
-
-
-
guanosine diphosphofucose glucoside alpha1->3fucosyltransferase
-
-
-
-
lewis-negative alpha-3-fucosyltransferase
-
-
-
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plasma alpha-3-fucosyltransferase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hexosyl group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
GDP-beta-L-fucose:beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R 3-alpha-L-fucosyltransferase (configuration-inverting)
Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. This enzyme fucosylates on O-3 of an N-acetylglucosamine that carries a galactosyl group on O-4, unlike EC 2.4.1.65, 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase, which fucosylates on O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3.
CAS REGISTRY NUMBER
COMMENTARY hide
111310-38-4
-
39279-34-0
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
additional information
?
-
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
Q70AH4_TAKRU
374
0
43743
TrEMBL
-
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Petit, D.; Maftah, A.; Julien, R.; Petit, J.M.
En bloc duplications, mutation rates, and densities of amino acid changes clarify the evolution of vertebrate alpha-1,3/4-fucosyltransferases
J. Mol. Evol.
63
353-364
2006
Ambystoma tigrinum (Q49ME5), Danio rerio (Q2VU44), Danio rerio (Q32WF4), Gallus gallus (Q8UVZ3), Homo sapiens (Q495W5), Takifugu rubripes (Q2KQ71), Takifugu rubripes (Q70AG8), Takifugu rubripes (Q70AG9), Takifugu rubripes (Q70AH0), Takifugu rubripes (Q70AH1), Takifugu rubripes (Q70AH2), Takifugu rubripes (Q70AH3), Takifugu rubripes (Q70AH4), Xenopus laevis (Q6WNG3), Xenopus tropicalis (Q49ME6)
Manually annotated by BRENDA team