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Information on EC - cytochrome-c oxidase

for references in articles please use BRENDA:EC1.9.3.1
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EC Tree
     1 Oxidoreductases
         1.9 Acting on a heme group of donors
             1.9.3 With oxygen as acceptor
       cytochrome-c oxidase
IUBMB Comments
A cytochrome of the a type containing copper. The reduction of O2 to water is accompanied by the extrusion of four protons from the intramitochondrial compartment. Several bacteria appear to contain analogous oxidases.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
cox, cytochrome c oxidase, cytochrome oxidase, complex iv, cytochrome c oxidase subunit i, cytochrome aa3, cytochrome c oxidase subunit 1, coxii, cytochrome a3, a-protein, more
4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O
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