Information on EC 1.8.4.B3 - thioredoxin-independent methionine sulfoxide reductases B and Organism(s) Homo sapiens and UniProt Accession Q8IXL7

for references in articles please use BRENDA:EC1.8.4.B3
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Homo sapiens
UNIPROT: Q8IXL7
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The taxonomic range for the selected organisms is: Homo sapiens

The enzyme appears in selected viruses and cellular organisms

EC NUMBER
COMMENTARY hide
1.8.4.B3
preliminary BRENDA-supplied EC number
RECOMMENDED NAME
GeneOntology No.
thioredoxin-independent methionine sulfoxide reductases B
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
L-methionine (R)-S-sulfoxide + thionein
L-methionine + thionein disulfide + H2O
show the reaction diagram
-
-
-
?
L-methionine (R)-S-sulfoxide + thioredoxin
L-methionine + thioredoxin disulfide
show the reaction diagram
reduced thioredoxin is not an efficient reducing agent for hMsrB3. Less than 5% of the activity with dithiothreitol
-
-
?
L-methionine (R)-sulfoxide + dithiothreitol
L-methionine + dithiothreitol disulfide
show the reaction diagram
-
-
-
?
L-methionine (R)-S-sulfoxide + dithiothreitol
L-methionine + dithiothreitol disulfide + H2O
show the reaction diagram
-
-
-
?
L-methionine (R)-S-sulfoxide + thionein
L-methionine + thionein disulfide + H2O
show the reaction diagram
-
-
-
?
L-methionine (R)-S-sulfoxide + thioredoxin
L-methionine + thioredoxin disulfide + H2O
show the reaction diagram
reduced thioredoxin is not an efficient reducing agent for hMsrB2. Less than 5% of the activity with dithiothreitol
-
-
?
additional information
?
-