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ferrocytochrome c-551 + O2
ferricytochrome c-551 + H2O
-
-
-
?
nitric oxide + H2O + ferricytochrome c551
nitrite + ferrocytochrome c551 + H+
-
-
-
r
nitrite + electron donor
NO + oxidized electron donor + H2O
-
-
-
?
ferrocytochrome c-551 + NO2-
NO + ferricytochrome c-551
-
-
-
?
ferrocytochrome c-551 + O2
ferricytochrome c-551 + H2O
ferrocytochrome c-551 + O2
H2O + ferricytochrome c-551
nitric oxide + H2O + ferricytochrome c
nitrite + ferrocytochrome c + H+
-
-
-
-
r
nitric oxide + H2O + ferricytochrome c551
nitrite + ferrocytochrome c551 + H+
-
-
-
-
r
nitrite + ferrocytochrome c
NO + H2O + ferricytochrome c
-
-
-
-
?
nitrite + reduced ascorbate
nitric oxide + oxidized ascorbate
-
-
-
-
r
NO2- + ferrocytochrome c
NO + ferricytochrome c
-
probably most dominant activity in vivo
-
?
NO2- + morpholine
N-nitrosomorpholine
-
in the presence of diethyldithiocarbamic acid ethylester, nitrosation through the production of NO or NO+-like species
-
?
reduced azurin + O2
oxidized azurin + H2O
-
not known whether azurin donates electrons in vivo in parallel or sequentially to cytochrome c551
-
?
additional information
?
-
ferrocytochrome c-551 + O2
ferricytochrome c-551 + H2O
-
-
-
?
ferrocytochrome c-551 + O2
ferricytochrome c-551 + H2O
-
-
-
-
?
ferrocytochrome c-551 + O2
H2O + ferricytochrome c-551
-
-
-
?
ferrocytochrome c-551 + O2
H2O + ferricytochrome c-551
-
-
-
?
ferrocytochrome c-551 + O2
H2O + ferricytochrome c-551
-
-
-
-
?
ferrocytochrome c-551 + O2
H2O + ferricytochrome c-551
-
inactive with eukaryotic cytochromes c
-
?
additional information
?
-
-
nitrite reductase from Pseudomonas aeruginosa released by antimicrobial agents and complement induces interleukin-8 production in bronchial epithelial cells
-
-
?
additional information
?
-
-
nitrite reductase in both oxidized and reduced states forms with NO two distinct compounds at both hemes. These compounds, in addition to the oxidized and reduced enzymes, are formed during the turnover of this enzyme as functional intermediates
-
-
?
additional information
?
-
-
spectroscopic analysis of the reactivity of cd1NiR and its semi-apo derivative with NO. The c heme nitrosylation is enhanced during catalysis
-
-
?
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Silvestrini, M.C.; Falcinelli, S.; Ciabatti, I.; Cutruzzola, F.; Brunori, M.
Pseudomonas aeruginosa nitrite reductase (or cytochrome oxidase): an overview
Biochimie
76
641-654
1994
Alcaligenes faecalis, Paracoccus denitrificans, Halomonas halodenitrificans, Paracoccus pantotrophus, Pseudomonas aeruginosa, Pseudomonas stutzeri, Thiobacillus denitrificans
brenda
Silvestrini, M.C.; Tordi, M.G.; Citro, G.; Vecchini, P.; Brunori, M.
Monomeric Pseudomonas aeruginosa nitrite reductase: preparation, characterization, and kinetic properties
J. Inorg. Biochem.
57
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1995
Pseudomonas aeruginosa
brenda
Yamazaki, T.; Oyanagi, H.; Fujiwara, T.; Fukumori, Y.
Nitrite reductase from the magnetotactic bacterium Magnetospirillum magnetotacticum. A novel cytochrome cd1 with Fe(II):nitrite oxidoreductase activity
Eur. J. Biochem.
233
665-671
1995
Magnetospirillum magnetotacticum, Pseudomonas aeruginosa
brenda
Schichman, S.A.; Meyer, T.E.; Gray, H.B.
Kinetics of electron transfer in Pseudomonas aeruginosa cytochrome cd1-nitrite reductase
Inorg. Chim. Acta
243
25-31
1996
Pseudomonas aeruginosa
-
brenda
Calmels, S.; Ohshima, H.; Henry, Y.; Bartsch, H.
Characterization of bacterial cytochrome cd(1)-nitrite reductase as one enzyme responsible for catalysis of nitrosation of secondary amines
Carcinogenesis
17
533-536
1996
Pseudomonas aeruginosa, Pseudomonas stutzeri
brenda
Cutruzzola, f.; Arese, M.; Grasso, S.; Bellelli, A.; Brunori, M.
Mutagenesis of nitrite reductase from Pseudomonas aeruginosa: tyrosine-10 in the c heme domain is not involved in catalysis
FEBS Lett.
412
365-369
1997
Pseudomonas aeruginosa
brenda
Ferguson, S.J.; Fulop, V.
Cytochrome cd1 nitrite reductase: structure raises interesting mechanistic questions
Subcell. Biochem.
35
519-540
2000
Paracoccus pantotrophus, Pseudomonas aeruginosa
brenda
Cutruzzola, F.; Brown, K.; Wilson, E.K.; Bellelli, A.; Arese, M.; Tegoni, M.
The nitrite reductase from Pseudomonas aeruginosa: essential role of two active-site histidines in the catalytic and structural properties
Proc. Natl. Acad. Sci. USA
98
2232-2237
2001
Pseudomonas aeruginosa (P24474)
brenda
Reutov, V.P.; Sorokina, E.G.
NO-Synthase and nitrite-reductase components of nitric oxide cycle
Biochemistry (Moscow)
63
874-884
1998
Paracoccus denitrificans, Pseudomonas aeruginosa
brenda
Arese, M.; Zumft, W.G.; Cutruzzola, F.
Expression of a fully functional cd1 nitrite reductase from Pseudomonas aeruginosa in Pseudomonas stutzeri
Protein Expr. Purif.
27
42-48
2003
Pseudomonas aeruginosa
brenda
Sar, B.; Oishi, K.; Wada, A.; Hirayama, T.; Matsushima, K.; Nagatake, T.
Nitrite reductase from Pseudomonas aeruginosa released by antimicrobial agents and complement induces interleukin-8 production in bronchial epithelial cells
Antimicrob. Agents Chemother.
43
794-801
1999
Pseudomonas aeruginosa, Pseudomonas aeruginosa 5276
brenda
Hull, H.H.; Wharton, D.C.
Isoelectrophoretic characterization of Pseudomonas cytochrome oxidase/nitrite reductase and its heme d1-containing domain
Arch. Biochem. Biophys.
301
85-90
1993
Pseudomonas aeruginosa
brenda
Silvestrini, M.C.; Cutruzzola, F.; D'Alessandro, R.; Brunori, M.; Fochesato, N.; Zennaro, E.
Expression of Pseudomonas aeruginosa nitrite reductase in Pseudomonas putida and characterization of the recombinant protein
Biochem. J.
285
661-666
1992
Pseudomonas aeruginosa
brenda
Bellelli, A.; Brzezinski, P.; Arese, M.; Cutruzolla, F.; Silvestrini, M.C.
Electron transfer in zinc-reconstituted nitrite reductase from Pseudomonas aeruginosa
Biochem. J.
319
407-410
1996
Pseudomonas aeruginosa
-
brenda
Nurizzo, D.; Cutruzzola, F.; Arese, M.; Bourgeois, D.; Brunori, M.; Cambillau, C.; Tegoni, M.
Conformational changes occurring upon reduction and NO binding in nitrite reductase from Pseudomonas aeruginosa
Biochemistry
37
13987-13996
1998
Pseudomonas aeruginosa (P24474), Pseudomonas aeruginosa
brenda
Karapetian, A.V.; Kamalian, M.G.; Nalbandyan, R.M.
A copper-containing protein that inhibits nitrite reductase from Pseudomonas aeruginosa
FEBS Lett.
203
131-134
1986
Pseudomonas aeruginosa
brenda
Shimada, H.; Orii, Y.
The nitric oxide compounds of Pseudomonas aeruginosa nitrite reductase and their probable participation in the nitrite reduction
FEBS Lett.
54
237-240
1975
Pseudomonas aeruginosa
brenda
Coyne, M.S.; Arunakumari, A.; Pankratz, H.S.; Tiedje, J.M.
Localization of the cytochrome cd1 and copper nitrite reductases in denitrifying bacteria
J. Bacteriol.
172
2558-2562
1990
Pseudomonas aeruginosa, Pseudomonas fluorescens
brenda
Shimada, H.; Orii, Y.
Oxidation-reduction behavior of the heme c and heme d moieties of Pseudomonas aeruginosa nitrite reductase and the formation of an oxygenated intermediate at heme d1
J. Biochem.
80
135-140
1976
Pseudomonas aeruginosa
brenda
Shimada, H.; Orii, Y.
The pH-dependent reactions of Pseudomonas aeruginosa nitrite reductase with nitric oxide and nitrite
J. Biochem.
84
1553-1558
1978
Pseudomonas aeruginosa
brenda
Yap-Bondoc, F.; Timkovich, R.
Inactivation of cytochrome cd1 by hydrazines
J. Biol. Chem.
265
4247-4253
1990
Pseudomonas aeruginosa
brenda
Takano, T.; Dickerson, R.E.; Schichman, S.A.; Meyer, T.E.
Crystal data, molecular dimensions and molecular symmetry in cytochrome oxidase from Pseudomonas aeruginosa
J. Mol. Biol.
133
185-188
1979
Pseudomonas aeruginosa
brenda
Tegoni, M.; Silvestrini, M.C.; Lamzin, V.S.; Brunori, M.; Cambillau, C.
Crystallization and preliminary X-ray analysis of a new crystal form of nitrite reductase from Pseudomonas aeruginosa
J. Mol. Biol.
243
347-350
1994
Pseudomonas aeruginosa
brenda
Brown, K.; Roig-Zamboni, V.; Cutruzzola, F.; Arese, M.; Sun, W.; Brunori, M.; Cambillau, C.; Tegoni, M.
Domain swing upon His to Ala mutation in nitrite reductase of Pseudomonas aeruginosa
J. Mol. Biol.
312
541-554
2001
Pseudomonas aeruginosa
brenda
Nurizzo, D.; Silvestrini, M.C.; Mathieu, M.; Cutruzzola, F.; Bourgeois, D.; Fulop, V.; Hajdu, J.; Brunori, M.; Tegoni, M.; Cambillau, C.
N-terminal arm exchange is observed in the 2.15 A crystal structure of oxidized nitrite reductase from Pseudomonas aeruginosa
Structure
5
1157-1171
1997
Pseudomonas aeruginosa
brenda
Centola, F.; Rinaldo, S.; Brunori, M.; Cutruzzola, F.
Critical role of His369 in the reactivity of Pseudomonas aeruginosa cytochrome cd1 nitrite reductase with oxygen
FEBS J.
273
4495-4503
2006
Pseudomonas aeruginosa
brenda
Radoul, M.; Centola, F.; Rinaldo, S.; Cutruzzola, F.; Pecht, I.; Goldfarb, D.
Heme d1 nitrosyl complex of cd1 nitrite reductase studied by high-field-pulse electron paramagnetic resonance spectroscopy
Inorg. Chem.
48
3913-3915
2009
Pseudomonas aeruginosa
brenda
Nicke, T.; Schnitzer, T.; Muench, K.; Adamczack, J.; Haufschildt, K.; Buchmeier, S.; Kucklick, M.; Felgentraeger, U.; Jaensch, L.; Riedel, K.; Layer, G.
Maturation of the cytochrome cd1 nitrite reductase NirS from Pseudomonas aeruginosa requires transient interactions between the three proteins NirS, NirN and NirF
Biosci. Rep.
33
e00048
2013
Pseudomonas aeruginosa
brenda
Rinaldo, S.; Giardina, G.; Cutruzzola, F.
Nitrosylation of c heme in cd(1)-nitrite reductase is enhanced during catalysis
Biochem. Biophys. Res. Commun.
451
449-454
2014
Pseudomonas aeruginosa
brenda