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Information on EC 1.2.3.7 - indole-3-acetaldehyde oxidase

for references in articles please use BRENDA:EC1.2.3.7

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IUBMB Comments

A hemoprotein. This enzyme is an isoform of aldehyde oxidase (EC 1.2.3.1). It has a preference for aldehydes having an indole-ring structure as substrate [6,7]. It may play a role in plant hormone biosynthesis as its activity is higher in the auxin-overproducing mutant, super-root1, than in wild-type Arabidopsis thaliana . While (indol-3-yl)acetaldehyde is the preferred substrate, it also oxidizes indole-3-carbaldehyde and acetaldehyde, but more slowly. The enzyme from maize contains FAD, iron and molybdenum .

The expected taxonomic range for this enzyme is: Eukaryota, Archaea

Synonyms
aogamma, indoleacetaldehyde oxidase, iaald oxidase, indole-3-acetaldehyde oxidase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(indol-3-yl)acetaldehyde + H2O + O2 = (indol-3-yl)acetate + H2O2
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
indole-3-acetate biosynthesis VI (bacteria), L-tryptophan degradation VI (via tryptamine)
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