Disease on EC 1.17.4.4 - vitamin-K-epoxide reductase (warfarin-sensitive)
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Acute Coronary Syndrome
Impact of CYP2C9 and VKORC1 genetic polymorphisms upon warfarin dose requirements in Egyptian patients with acute coronary syndrome.
Anemia
Revalidation of CoaguChek XS plus system for INR monitoring in Taiwanese patients: effects of clinical and genetic factors.
Aneurysm
The VKORC1 polymorphism rs9923231 is associated with aneurysms of the ascending aorta in an Austrian population.
Aneurysm, Dissecting
Functional promoter polymorphism in the VKORC1 gene is no major genetic determinant for coronary heart disease in Northern Germans.
Aneurysm, Dissecting
VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection).
Atherosclerosis
Association of VKORC1 -1639 G>A polymorphism with carotid intima-media thickness in type 2 diabetes mellitus.
Atherosclerosis
Relationship between VKORC1 single nucleotide polymorphism 1173C>T, bone mineral density & carotid intima-media thickness.
Atherosclerosis
VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection).
Atherosclerosis
VKORC1 rs2359612C allele is associated with increased risk of coronary artery disease in the presence of coronary calcification.
Atrial Fibrillation
A new algorithm to predict warfarin dose from polymorphisms of CYP4F2 , CYP2C9 and VKORC1 and clinical variables: derivation in Han Chinese patients with non valvular atrial fibrillation.
Atrial Fibrillation
Clinical and genetic factors influencing acenocoumarol dosing: a cross-sectional study.
Atrial Fibrillation
Clinical application of a new warfarin-dosing regimen based on the CYP2C9 and VKORC1 genotypes in atrial fibrillation patients.
Atrial Fibrillation
Comparison of aspirin and Naoxintong Capsule () with adjusted-dose warfarin in elderly patients with high-risk of non-valvular atrial fibrillation and genetic variants of vitamin K epoxide reductase.
Atrial Fibrillation
CYP4F2 and VKORC1 Polymorphisms Amplify the Risk of Carotid Plaque Formation.
Atrial Fibrillation
DNA sensors to assess the effect of VKORC1 and CYP2C9 gene polymorphisms on warfarin dose requirement in Chinese patients with atrial fibrillation.
Atrial Fibrillation
Factors affecting the interindividual variability of warfarin dose requirement in adult Korean patients.
Atrial Fibrillation
Genetic causes of resistance to vitamin K antagonists in Polish patients: a novel p.Ile123Met mutation in VKORC1 gene.
Atrial Fibrillation
Genetic variant in the promoter region of microRNA?137 reduces the warfarin maintenance dose in patients with atrial fibrillation.
Atrial Fibrillation
Impact of VKORC1, CYP4F2 and NQO1 gene variants on warfarin dose requirement in Han Chinese patients with catheter ablation for atrial fibrillation.
Atrial Fibrillation
Incidence, mortality, and risk factors for oral anticoagulant-associated intracranial hemorrhage in patients with atrial fibrillation.
Atrial Fibrillation
Performance Evaluation of Warfarin Dose Prediction Algorithms and Effects of Clinical Factors on Warfarin Dose in Chinese Patients.
Atrial Fibrillation
Pharmacogenetics of vitamin K antagonists and bleeding risk prediction in atrial fibrillation.
Atrial Fibrillation
Polymorphisms of CYP2C9*2, CYP2C9*3 and VKORC1 genes related to time in therapeutic range in patients with atrial fibrillation using warfarin.
Atrial Fibrillation
Prediction of stable acenocoumarol dose by a pharmacogenetic algorithm.
Atrial Fibrillation
Quantifying the Effect of Covariates on Concentrations and Effects of Steady-State Phenprocoumon Using a Population Pharmacokinetic/Pharmacodynamic Model.
Atrial Fibrillation
Universal versus genotype-guided use of direct oral anticoagulants in atrial fibrillation patients: a decision analysis.
Atrial Fibrillation
Warfarin dose requirement with different genotypes of polymorphisms on CYP2C9 and VKORC1 and indications in Han-Chinese patients.
Atrial Fibrillation
Warfarin dosing according to the genotype-guided algorithm is most beneficial in patients with atrial fibrillation: a randomized parallel group trial.
Atrial Fibrillation
Warfarin pharmacogenetics: development of a dosing algorithm for Omani patients.
Atrial Fibrillation
[Association of VKORC1 gene -1639G/A polymorphism with atrial fibrillation in ethnic Uygurs and Hans from Xinjiang].
Bone Diseases, Metabolic
Relationship between VKORC1 single nucleotide polymorphism 1173C>T, bone mineral density & carotid intima-media thickness.
Breast Neoplasms
Challenges and pitfalls in the introduction of pharmacogenetics for cancer.
Breast Neoplasms
Divergent effects of vitamins K1 and K2 on triple negative breast cancer cells.
Budd-Chiari Syndrome
Mutations in CYP2C9 and/or VKORC1 haplotype are associated with higher bleeding complications in patients with Budd-Chiari syndrome on warfarin.
Carcinoma, Hepatocellular
mTOR and ERK regulate VKORC1 expression in both hepatoma cells and hepatocytes which influence blood coagulation.
Carcinoma, Hepatocellular
Vitamin K epoxide reductase contributes to protein disulfide formation and redox homeostasis within the endoplasmic reticulum.
Carcinoma, Hepatocellular
VKORC1 haplotypes influence the performance characteristics of PIVKAII for screening of hepatocellular carcinoma.
Cardiovascular Diseases
miR-133a regulates vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1), a key protein in the vitamin K cycle.
Cardiovascular Diseases
Missense mutation of VKORC1 leads to medial arterial calcification in rats.
Cardiovascular Diseases
Pharmacogenetics of Anticoagulation and Clinical Events in Warfarin-Treated Patients: A Register-Based Cohort Study with Biobank Data and National Health Registries in Finland.
Cardiovascular Diseases
Sequence variation in vitamin K epoxide reductase gene is associated with survival and progressive coronary calcification in chronic kidney disease.
Cardiovascular Diseases
VKORC1 gene (vitamin K epoxide reductase) polymorphisms are associated with cardiovascular disease in chronic kidney disease patients on hemodialysis.
Cerebrovascular Disorders
Association Between VKORC1 Gene Polymorphisms and Ischemic Cerebrovascular Disease in Chinese Han Population.
Cerebrovascular Disorders
Pharmacogenetic Testing for Guiding de novo Phenprocoumon Therapy in Stroke Patients.
Cerebrovascular Disorders
VKORC1 and CD-14 genetic polymorphisms associate with susceptibility to cardiovascular and cerebrovascular diseases.
Cerebrovascular Disorders
VKORC1 rs2359612 and rs9923231 polymorphisms correlate with high risks of cardiovascular and cerebrovascular diseases.
Congenital Abnormalities
A novel role for vitamin K1 in a tyrosine phosphorylation cascade during chick embryogenesis.
Coronary Artery Disease
VKORC1 rs2359612C allele is associated with increased risk of coronary artery disease in the presence of coronary calcification.
Coronary Disease
Functional promoter polymorphism in the VKORC1 gene is no major genetic determinant for coronary heart disease in Northern Germans.
Coronary Disease
Lack of association between variants in the VKORC1 gene and cerebrovascular or coronary heart disease.
Coronary Disease
Single nucleotide polymorphisms in the VKORC1 gene and the risk of stroke in the Southern German population.
Coronary Disease
VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection).
COVID-19
Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection.
COVID-19
Understand variability of COVID-19 through population and tissue variations in expression of SARS-CoV-2 host genes.
COVID-19
Vitamin K epoxide reductase complex subunit 1 (VKORC1) gene polymorphism as determinant of differences in Covid-19-related disease severity.
Diabetes Mellitus
Association of VKORC1 -1639 G>A polymorphism with carotid intima-media thickness in type 2 diabetes mellitus.
Diabetes Mellitus
CYP4F2 and VKORC1 Polymorphisms Amplify the Risk of Carotid Plaque Formation.
Diabetes Mellitus
Role of the Vitamin K Epoxide Reductase Complex Subunit 1 (VKORC1) -1639G>A Gene Polymorphism in Patients with Retinal Vein Occlusion.
Diabetes Mellitus, Type 2
Association of VKORC1 -1639 G>A polymorphism with carotid intima-media thickness in type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Lack of Association Between Type 2 Diabetes and the 3673G / A and 9041G / A Gene Variants of Vitamin K Epoxide Reductase Complex Subunit 1 (VKORC1).
Drug-Related Side Effects and Adverse Reactions
Pharmacogenetic testing of CYP2C9 and VKORC1 alleles for warfarin.
Drug-Related Side Effects and Adverse Reactions
Pharmacogenetics of Anticoagulation and Clinical Events in Warfarin-Treated Patients: A Register-Based Cohort Study with Biobank Data and National Health Registries in Finland.
Drug-Related Side Effects and Adverse Reactions
Warfarin Dosing in a Patient with CYP2C9(?)3(?)3 and VKORC1-1639 AA Genotypes.
Dyslipidemias
CYP4F2 and VKORC1 Polymorphisms Amplify the Risk of Carotid Plaque Formation.
Embolic Stroke
Warfarin loading dose guided by pharmacogenetics is effective and safe in cardioembolic stroke patients - a randomized, prospective study.
Essential Hypertension
Susceptiveness of Vitamin K epOxide Reductase Complex Subunit 1 Gene Polymorphism in Essential Hypertension.
Fetal Diseases
A novel role for vitamin K1 in a tyrosine phosphorylation cascade during chick embryogenesis.
Fetal Diseases
Male infant with ichthyosis, Kallmann syndrome, chondrodysplasia punctata, and an Xp chromosome deletion.
Heart Diseases
CYP4F2 and VKORC1 Polymorphisms Amplify the Risk of Carotid Plaque Formation.
Heart Diseases
Genetic and clinical determinants influencing warfarin dosing in children with heart disease.
Heart Diseases
Vitamin K antagonists in children with heart disease: height and VKORC1 genotype are the main determinants of the warfarin dose requirement.
Heart Failure
CYP4F2 and VKORC1 Polymorphisms Amplify the Risk of Carotid Plaque Formation.
Heart Failure
The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population.
Heart Valve Diseases
Prevalence of CYP2C9 and VKORC1 mutation in patients with valvular heart disease in northern Thailand.
Heart Valve Diseases
VKORC1 -1639G/A and 1173 C/T Genetic Polymorphisms Influence Individual Differences in Warfarin Maintenance Dose.
Hepatitis B
Seven novel probe systems for real-time PCR provide absolute single-base discrimination, higher signaling, and generic components.
Hepatitis B
VKORC1 haplotypes influence the performance characteristics of PIVKAII for screening of hepatocellular carcinoma.
Hypersensitivity
Unexpected acute pulmonary embolism in an old COVID-19 patient with warfarin overdose: a case report.
Hypersensitivity
[Impact of pharmacogenetics on interindividual variability in the response to vitamin K antagonist therapy]
Hypersensitivity
[Resistance to acenocoumarol revealing a missense mutation of the vitamin K epoxyde reductase VKORC1: A case report.]
Hypertension
Role of the Vitamin K Epoxide Reductase Complex Subunit 1 (VKORC1) -1639G>A Gene Polymorphism in Patients with Retinal Vein Occlusion.
Hypertension
The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population.
Hypoalbuminemia
Revalidation of CoaguChek XS plus system for INR monitoring in Taiwanese patients: effects of clinical and genetic factors.
Hypoprothrombinemias
Depression of liver microsomal vitamin K epoxide reductase activity associated with antibiotic-induced coagulopathy.
Hypoprothrombinemias
Mechanism of cephalosporin-induced hypoprothrombinemia: relation to cephalosporin side chain, vitamin K metabolism, and vitamin K status.
Hypoprothrombinemias
[Hemostasis disturbance caused by cephalosporins with an N-methylthiotetrazole side chain. A randomized pilot study]
Influenza, Human
Seven novel probe systems for real-time PCR provide absolute single-base discrimination, higher signaling, and generic components.
Ischemic Stroke
Association of functional VKORC1 promoter polymorphism with occurrence and clinical aspects of ischemic stroke in a Greek population.
Ischemic Stroke
Effect of CYP2C9 *11/*11 genotype on initial and long-term warfarin dose requirement and therapeutic response.
Ischemic Stroke
G-1639A but Not C1173T VKORC1 Gene Polymorphism Is Related to Ischemic Stroke and Its Various Risk Factors in Ukrainian Population.
Ischemic Stroke
Genotypes of vitamin K epoxide reductase, gamma-glutamyl carboxylase, and cytochrome P450 2C9 as determinants of daily warfarin dose in Japanese patients.
Ischemic Stroke
Single nucleotide polymorphisms in the VKORC1 gene and the risk of stroke in the Southern German population.
Kidney Failure, Chronic
Clinical and genetic factors influencing acenocoumarol dosing: a cross-sectional study.
Lupus Erythematosus, Systemic
Brief Report: Single-nucleotide polymorphisms in VKORC1 are risk factors for systemic lupus erythematosus in Asians.
Lymphoma
Human herpesvirus 8 interleukin-6 contributes to primary effusion lymphoma cell viability via suppression of proapoptotic cathepsin D, a cointeraction partner of vitamin K epoxide reductase complex subunit 1 variant 2.
Lymphoma
Insulin-Like Growth Factor 2 Receptor Expression Is Promoted by Human Herpesvirus 8-Encoded Interleukin-6 and Contributes to Viral Latency and Productive Replication.
Lymphoma
Promotion of Endoplasmic Reticulum-Associated Degradation of Procathepsin D by Human Herpesvirus 8-Encoded Viral Interleukin-6.
Lymphoma, Primary Effusion
Human herpesvirus 8 interleukin-6 contributes to primary effusion lymphoma cell viability via suppression of proapoptotic cathepsin D, a cointeraction partner of vitamin K epoxide reductase complex subunit 1 variant 2.
Lymphoma, Primary Effusion
Insulin-Like Growth Factor 2 Receptor Expression Is Promoted by Human Herpesvirus 8-Encoded Interleukin-6 and Contributes to Viral Latency and Productive Replication.
Lymphoma, Primary Effusion
Promotion of Endoplasmic Reticulum-Associated Degradation of Procathepsin D by Human Herpesvirus 8-Encoded Viral Interleukin-6.
Mucocutaneous Lymph Node Syndrome
Height, VKORC1 1173, and CYP2C9 Genotypes Determine Warfarin Dose for Pediatric Patients with Kawasaki Disease in Southwest China.
Myocardial Infarction
Genetic variation of VKORC1 and CYP4F2 genes related to warfarin maintenance dose in patients with myocardial infarction.
Myocardial Infarction
Warfarin dose and INR related to genotypes of CYP2C9 and VKORC1 in patients with myocardial infarction.
Myocardial Ischemia
CYP4F2 and VKORC1 Polymorphisms Amplify the Risk of Carotid Plaque Formation.
Myxoma
A rare combination of CYP2C9*3/*3 and VKORC1 1639AA in a patient had myxoma and thromboembolism.
Neoplasms
Effects of inflammatory cytokine gene polymorphisms on warfarin maintenance doses in Korean patients with mechanical cardiac valves.
Neoplasms
Novel isomeric metabolite profiles correlate with warfarin metabolism phenotype during maintenance dosing in a pilot study of 29 patients.
Neoplasms
The point mutation analysis of Cyp2C9*2 (Arg144Cys C>T), Cyp2C9*3 (Ile359Leu A>C) and VKORC1 (1639G>A) in women with cervical cancer related to HPV: A case-control study.
Neoplasms
VKORC1 haplotypes influence the performance characteristics of PIVKAII for screening of hepatocellular carcinoma.
Neuroblastoma
Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients.
Obesity
Polymorphisms of VKORC1 and CYP2C9 are associated with warfarin sensitivity in Chinese population.
Obesity
The Impact of Body Mass Index and Genetics on Warfarin Major Bleeding Outcomes in a Community Setting.
Obesity
The Vitamin K Epoxide Reductase Vkorc1l1 Promotes Preadipocyte Differentiation in Mice.
Osteoporosis
Association Between Vitamin K Epoxide Reductase (VKORC1) -1639G>A Polymorphism and Osteoporosis in Postmenopausal Women.
Osteoporosis
Is there any association between osteoporotic vertebral fracture and vitamin K epoxide reductase complex subunit-1 polymorphism in Turkish society? A pilot study.
Osteoporosis
Polymorphisms of FDPS, LRP5, SOST and VKORC1 genes and their relation with osteoporosis in postmenopausal Romanian women.
Osteoporosis
Relationship between VKORC1 single nucleotide polymorphism 1173C>T, bone mineral density & carotid intima-media thickness.
Osteoporosis
Vitamin K epoxide reductase (VKORC1) gene mutations in osteoporosis: A pilot study.
Osteoporosis
VKORC1 common variation and bone mineral density in the Third National Health and Nutrition Examination Survey.
Osteoporosis, Postmenopausal
Association Between Vitamin K Epoxide Reductase (VKORC1) -1639G>A Polymorphism and Osteoporosis in Postmenopausal Women.
Peripheral Arterial Disease
No clear link between VKORC1 genetic polymorphism and the risk of venous thrombosis or peripheral arterial disease.
Prostatic Neoplasms
Serum undercarboxylated osteocalcin as biomarker of vitamin K intake and risk of prostate cancer: a nested case-control study in the Heidelberg cohort of the European prospective investigation into cancer and nutrition.
Pulmonary Embolism
ARMS test for diagnosis of CYP2C9 and VKORC1 mutation in patients with pulmonary embolism in Han Chinese.
Pulmonary Embolism
Comparison of rivaroxaban mono-therapy and standard-therapy adjusted by CYP2C9 and VKORC1 genotypes in symptomatic pulmonary embolism.
Pulmonary Fibrosis
VKORC1 and CYP2C9 Polymorphisms: A Case Report in a Dutch Family with Pulmonary Fibrosis.
Renal Insufficiency, Chronic
Race influences warfarin dose changes associated with genetic factors.
Renal Insufficiency, Chronic
Sequence variation in vitamin K epoxide reductase gene is associated with survival and progressive coronary calcification in chronic kidney disease.
Renal Insufficiency, Chronic
VKORC1 gene (vitamin K epoxide reductase) polymorphisms are associated with cardiovascular disease in chronic kidney disease patients on hemodialysis.
Retinal Vein Occlusion
Predictive value of the vkorc1 g-1639a and vkorc1 c1173t single nucleotide polymorphisms in retinal vein occlusion.
Retinal Vein Occlusion
Role of the Vitamin K Epoxide Reductase Complex Subunit 1 (VKORC1) -1639G>A Gene Polymorphism in Patients with Retinal Vein Occlusion.
Rheumatic Heart Disease
Clinical application of pharmacogenetic-based warfarin-dosing algorithm in patients of han nationality after rheumatic valve replacement: a randomized and controlled trial.
Stroke
Clinical Application of Genotype-guided Dosing of Warfarin in Patients with Acute Stroke.
Stroke
Effect of gene-gene and gene-environment interaction on the risk of first-ever stroke and poststroke death.
Stroke
Functional promoter polymorphism in the VKORC1 gene is no major genetic determinant for coronary heart disease in Northern Germans.
Stroke
Genome-Wide Association Study of VKORC1 and CYP2C9 on acenocoumarol dose, stroke recurrence and intracranial haemorrhage in Spain.
Stroke
Genotype polymorphisms of GGCX, NQO1, and VKORC1 genes associated with risk susceptibility in patients with large-artery atherosclerotic stroke.
Stroke
Incidence, mortality, and risk factors for oral anticoagulant-associated intracranial hemorrhage in patients with atrial fibrillation.
Stroke
Prevalence of combinatorial CYP2C9 and VKORC1 genotypes in Puerto Ricans: implications for warfarin management in Hispanics.
Stroke
Prevalence of genetic polymorphisms of CYP2C9 and VKORC1 - implications for warfarin management and outcome in Croatian patients with acute stroke.
Stroke
Single nucleotide polymorphisms in the VKORC1 gene and the risk of stroke in the Southern German population.
Stroke
Universal versus genotype-guided use of direct oral anticoagulants in atrial fibrillation patients: a decision analysis.
Stroke
Utilizing Whole-Exome Sequencing to Characterize the Phenotypic Variability of Sickle Cell Disease.
Stroke
VKORC1 and CYP2C9 Genotype Variations in Relation to Warfarin Dosing in Korean Stroke Patients.
Stroke
VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection).
Thromboembolism
A rare combination of CYP2C9*3/*3 and VKORC1 1639AA in a patient had myxoma and thromboembolism.
Thromboembolism
Comparison of aspirin and Naoxintong Capsule () with adjusted-dose warfarin in elderly patients with high-risk of non-valvular atrial fibrillation and genetic variants of vitamin K epoxide reductase.
Thrombophilia
Increased warfarin consumption and residual fibrin turnover in thrombotic patients with primary antiphospholipid syndrome.
Thrombophilia
Population study of thrombophilic markers and pharmacogenetic markers of warfarin prevalence in Bosnia and Herzegovina.
Thrombophilia
Warfarin dose requirement in patients having severe thrombosis or thrombophilia.
Thrombosis
A new cell culture-based assay quantifies VKORC1 function and reveals warfarin resistance phenotypes not shown by the DTT-driven VKOR assay.
Thrombosis
An evaluation of gene-gene interaction between the CYP2C9 and VKORC1 genotypes affecting the anticoagulant effect of phenprocoumon and acenocoumarol.
Thrombosis
Antithrombotic Activity of the Novel Oral Anticoagulant, Tecarfarin [Sodium 3-[4-((1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yloxy) carbonyl) benzyl]-2-oxo-2H-chromen-4-olate] in Animal Models.
Thrombosis
Genotyping of CYP2C9 and VKORC1 polymorphisms predicts south Indian patients with deep vein thrombosis as fast metabolizers of warfarin/acenocoumarin.
Thrombosis
Polymorphisms of CYP2C9, VKORC1, MDR1, APOE and UGT1A1 genes and the therapeutic warfarin dose in Brazilian patients with thrombosis: a prospective cohort study.
Thrombosis
Prosthetic valve thrombosis - association of genetic polymorphisms of VKORC1, CYP2C9 and CYP4F2 genes.
Thrombosis
The Influence of VKORC1 Polymorphisms on Warfarin Doses in Thai Patients with Deep Vein Thrombosis.
Thrombosis
Thrombotic genetic risk factors and warfarin pharmacogenetic variants in São Miguel's healthy population (Azores).
Thrombosis
Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin.
Thrombosis
VKORC1 and VKORC1L1 have distinctly different oral anticoagulant dose-response characteristics and binding sites.
Thrombosis
VKORC1 C1173T and VKORC1 G-1639A Gene Polymorphisms in Turkish Behçet's Patients with Ocular and Non-ocular Involvement.
Thrombosis
Warfarin dose requirement in patients having severe thrombosis or thrombophilia.
Thrombosis
[Factors associated with thrombosis of the left atrial appendage in patients with chronic atrial fibrillation].
Thrombosis
[FREQUENCY OF POLYMORPHISM OF VKORC1 AND CYP2C9 GENES IN TWO REGIONS OF GEORGIA].
Triple Negative Breast Neoplasms
Divergent effects of vitamins K1 and K2 on triple negative breast cancer cells.
Tuberculosis
Membrane Topology and Mutational Analysis of Mycobacterium tuberculosis VKOR, a Protein Involved in Disulfide Bond Formation and a Homologue of Human Vitamin K Epoxide Reductase.
Tuberculosis
Mycobacterium tuberculosis vitamin K epoxide reductase homologue supports vitamin K-dependent carboxylation in mammalian cells.
Tuberculosis
Seven novel probe systems for real-time PCR provide absolute single-base discrimination, higher signaling, and generic components.
Urolithiasis
Decreased expression of vitamin K epoxide reductase complex subunit 1 in kidney of patients with calcium oxalate urolithiasis.
Urolithiasis
Involvement of VKORC1 in the inhibition of calcium oxalate crystal formation in HK-2 cells.
Urolithiasis
Re: Decreased expression of vitamin k epoxide reductase complex subunit 1 in kidney of patients with calcium oxalate urolithiasis.
Uterine Cervical Neoplasms
The point mutation analysis of Cyp2C9*2 (Arg144Cys C>T), Cyp2C9*3 (Ile359Leu A>C) and VKORC1 (1639G>A) in women with cervical cancer related to HPV: A case-control study.
Varicose Veins
VKORC1 -1639 G>A Polymorphism in Romanian Patients With Deep Vein Thrombosis.
Vascular Calcification
Association of functional VKORC1 promoter polymorphism with occurrence and clinical aspects of ischemic stroke in a Greek population.
Vascular Calcification
Decreased expression of ?-carboxylase in diabetes-associated arterial stiffness: impact on matrix Gla protein.
Vascular Calcification
Missense mutation of VKORC1 leads to medial arterial calcification in rats.
Vascular Calcification
Relationship between VKORC1 single nucleotide polymorphism 1173C>T, bone mineral density & carotid intima-media thickness.
Vascular Calcification
Vitamin K epoxide reductase complex and vascular calcification: is this the important link between vitamin K and the arterial vessel wall?
Vascular Calcification
VKORC1 gene (vitamin K epoxide reductase) polymorphisms are associated with cardiovascular disease in chronic kidney disease patients on hemodialysis.
Vascular Diseases
Impact of VKORC1 haplotypes on long-term graft function in kidney transplantation.
Vascular Diseases
Vitamin K epoxide reductase complex subunit 1 gene polymorphism is associated with atherothrombotic complication after drug-eluting stent implantation: 2-Center prospective cohort study.
Vascular Diseases
Vitamin K epoxide reductase genetic polymorphism is associated with venous thromboembolism: results from the EDITH Study.
Vascular Diseases
VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection).
Venous Thromboembolism
A regression model to predict warfarin dose from clinical variables and polymorphisms in CYP2C9, CYP4F2, and VKORC1: Derivation in a sample with predominantly a history of venous thromboembolism.
Venous Thromboembolism
Frequency of vitamin K oxidoreductase complex subunit-1 (VKORC1) polymorphisms and warfarin dose management in patients with venous thromboembolism.
Venous Thromboembolism
Prediction of stable acenocoumarol dose by a pharmacogenetic algorithm.
Venous Thromboembolism
Vitamin K epoxide reductase genetic polymorphism is associated with venous thromboembolism: results from the EDITH Study.
Venous Thromboembolism
VKORC1 and CYP2C9 polymorphisms are associated with warfarin dose requirements in Turkish patients.
Venous Thromboembolism
VKORC1 genetic polymorphism and risk of venous thromboembolism in postmenopausal women: new findings and metaanalysis.
Venous Thrombosis
Common VKORC1 variants are not associated with arterial or venous thrombosis.
Venous Thrombosis
Genotyping of CYP2C9 and VKORC1 polymorphisms predicts south Indian patients with deep vein thrombosis as fast metabolizers of warfarin/acenocoumarin.
Venous Thrombosis
Haplotypes of VKORC1, NQO1 and GGCX, their effect on activity levels of vitamin K-dependent coagulation factors, and the risk of venous thrombosis.
Venous Thrombosis
No clear link between VKORC1 genetic polymorphism and the risk of venous thrombosis or peripheral arterial disease.
Venous Thrombosis
Single nucleotide polymorphisms in the VKORC1 gene and the risk of stroke in the Southern German population.
Venous Thrombosis
The Influence of VKORC1 Polymorphisms on Warfarin Doses in Thai Patients with Deep Vein Thrombosis.
Venous Thrombosis
VKORC1 -1639 G>A Polymorphism in Romanian Patients With Deep Vein Thrombosis.
Venous Thrombosis
VKORC1 and CYP2C9 genotypes in Egyptian patients with warfarin resistance.
Venous Thrombosis
VKORC1 gene variation and venous thrombosis: 'another one bites the dust'?
Vitamin K Deficiency
Understand variability of COVID-19 through population and tissue variations in expression of SARS-CoV-2 host genes.
vitamin-k-epoxide reductase (warfarin-sensitive) deficiency
A novel role for vitamin K1 in a tyrosine phosphorylation cascade during chick embryogenesis.
vitamin-k-epoxide reductase (warfarin-sensitive) deficiency
Binder phenotype: associated findings and etiologic mechanisms.
vitamin-k-epoxide reductase (warfarin-sensitive) deficiency
Male infant with ichthyosis, Kallmann syndrome, chondrodysplasia punctata, and an Xp chromosome deletion.
vitamin-k-epoxide reductase (warfarin-sensitive) deficiency
The Vitamin K Epoxide Reductase Vkorc1l1 Promotes Preadipocyte Differentiation in Mice.
vitamin-k-epoxide reductase (warfarin-sensitive) deficiency
VKORC1 deficiency in mice causes early postnatal lethality due to severe bleeding.
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