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Information on EC 1.14.99.51 - hercynylcysteine S-oxide synthase

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IUBMB Comments
Requires Fe2+ for activity. The enzyme, found in fungal species, is part of a fusion protein that also has the the activity of EC 2.1.1.44, L-histidine Nalpha-methyltransferase. It is part of the biosynthesis pathway of ergothioneine. The enzyme can also use L-selenocysteine to produce hercynylselenocysteine, which can be converted to selenoneine.
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The enzyme appears in viruses and cellular organisms
Synonyms
egt-1, egt1+, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
hercynine + L-cysteine + O2 = S-(hercyn-2-yl)-L-cysteine S-oxide + H2O
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PATHWAY SOURCE
PATHWAYS
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