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Disease on EC 1.14.14.3 - bacterial luciferase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acidosis
Promoter polymorphism of the anion-exchange protein 1 associated with severe malarial anemia and fatality.
Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells.
Acute Coronary Syndrome
MiR-29b mimics promotes cell apoptosis of smooth muscle cells via targeting on MMP-2.
Acute Lung Injury
Comprehensive Analysis of LncRNA-mRNA Expression Profiles and the ceRNA Network Associated with Pyroptosis in LPS-Induced Acute Lung Injury.
Adenocarcinoma
Anti-estrogenic activity of a human resveratrol metabolite.
Bioluminescence imaging reveals inhibition of tumor cell proliferation by Alzheimer's amyloid beta protein.
DDT and its metabolites alter gene expression in human uterine cell lines through estrogen receptor-independent mechanisms.
Development and characterization of a new plasmid delivery system based on chitosan-sodium deoxycholate nanoparticles.
Development of an Image-Guided Orthotopic Xenograft Mouse Model of Endometrial Cancer with Controllable Estrogen Exposure.
Diagnostic and therapeutic evaluation of 111In-vinorelbine-liposomes in a human colorectal carcinoma HT-29/luc-bearing animal model.
Dysfunctional transforming growth factor-? signaling with constitutively active notch signaling in Barrett's esophageal Adenocarcinoma.
Early therapy evaluation of combined cetuximab and irinotecan in orthotopic pancreatic tumor xenografts by dynamic contrast-enhanced magnetic resonance imaging.
Effects of progestins and relaxin on glycodelin gene expression in human endometrial cells.
Exosurf enhances adenovirus-mediated gene transfer to alveolar type II cells.
Hydrogen peroxide-mediated nuclear factor kappaB activation in both liver and tumor cells during initial stages of hepatic metastasis.
Hydroxylated polychlorinated biphenyl metabolites are anti-estrogenic in a stably transfected human breast adenocarcinoma (MCF7) cell line.
In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers.
In-silico Molecular Interaction of Short Synthetic Lipopeptide/Importin-alpha and In-vitro Evaluation of Transgene Expression Mediated by Liposome- Based Gene Carrier.
Inhibition of human gastric H(+)-K(+)-ATPase alpha-subunit gene expression by Helicobacter pylori.
Inhibition of NF-kappaB and HIV-1 long terminal repeat transcriptional activation by inducible nitric oxide synthase 2 activity.
Interleukin-12 gene transfer results in CD8-dependent regression of murine CT26 liver tumors.
Luciferase Expression Allows Bioluminescence Imaging But Imposes Limitations on the Orthotopic Mouse (4T1) Model of Breast Cancer.
MicroRNA target prediction: theory and practice.
microRNA-377-3p downregulates the oncosuppressor T-cadherin in colorectal adenocarcinoma cells.
Modulation of AP-1 activity by the human progesterone receptor in endometrial adenocarcinoma cells.
Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence.
Pharmacological inhibition of 17?-hydroxysteroid dehydrogenase impairs human endometrial cancer growth in an orthotopic xenograft mouse model.
Phosphatidylinositol 3-kinase-dependent suppression of the human inducible nitric-oxide synthase promoter is mediated by FKHRL1.
Phytoestrogens induce differential estrogen receptor alpha- or Beta-mediated responses in transfected breast cancer cells.
Promoter analysis of human corticotropin-releasing factor (CRF) type 1 receptor and regulation by CRF and urocortin.
Recombinant PAPP-A resistant insulin-like growth factor binding protein 4 (dBP4) inhibits angiogenesis and metastasis in a murine model of breast cancer.
Regulation of mammalian gastrin/CCK receptor (CCK2R) expression in vitro and in vivo.
Regulation of the human leukaemia inhibitory factor (LIF) promoter in HEC-1B endometrial adenocarcinoma cells.
Small nanosized poly(vinyl benzyl trimethylammonium chloride) based polyplexes for siRNA delivery.
Species-specific transcriptional activity of synthetic flavonoids in guinea pig and mouse cells as a result of differential activation of the aryl hydrocarbon receptor to interact with dioxin-responsive elements.
Traffic to lymph nodes of PC-3 prostate tumor cells in nude mice visualized using the luciferase gene as a tumor cell marker.
Transcriptional activation of gene expression by pluronic block copolymers in stably and transiently transfected cells.
Transfection Studies with Colloidal Systems Containing Highly Purified Bipolar Tetraether Lipids from Sulfolobus acidocaldarius.
Transplantation of cancerous cell sheets effectively generates tumour-bearing model mice.
Validation of a genotoxicity test based on p53R2 gene expression in human lymphoblastoid cells.
Wnt/?-Catenin Signaling Activation beyond Robust Nuclear ?-Catenin Accumulation in Nondysplastic Barrett's Esophagus: Regulation via Dickkopf-1.
Adenocarcinoma of Lung
Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells.
ASAP3 is a downstream target of HIF-1? and is critical for progression of lung adenocarcinoma.
Efficacy of Gefitinib Combined with 125I Radioactive Particles in the Treatment of Transplanted Lung Cancer Tumors in Nude Mice.
Human SP-A1 (SFTPA1) variant-specific 3' UTRs and poly(A) tail differentially affect the in vitro translation of a reporter gene.
Hypoxic tumor-derived exosomal circular RNA SETDB1 promotes invasive growth and EMT via the miR-7/Sp1 axis in lung adenocarcinoma.
IL-6 stimulates annexin 1 expression and translocation and suggests a new biological role as class II acute phase protein.
In vivo MRI for effective non-invasive detection and follow-up of an orthotopic mouse model of lung cancer.
MicroRNA-33b inhibits lung adenocarcinoma cell growth, invasion, and epithelial-mesenchymal transition by suppressing Wnt/?-catenin/ZEB1 signaling.
MiR-222 promotes proliferation, migration and invasion of lung adenocarcinoma cells by targeting ETS1.
miR-363-3p inhibits tumor growth by targeting PCNA in lung adenocarcinoma.
MiR-485 inhibits metastasis and EMT of lung adenocarcinoma by targeting Flot2.
Monitoring luciferase-labeled cancer cell growth and metastasis in different in vivo models.
Novel mechanisms for osteogenic differentiation of human aortic valve interstitial cells.
PRDM16 functions as a suppressor of lung adenocarcinoma metastasis.
Resveratrol attenuates pulmonary embolism associated cardiac injury by suppressing activation of the inflammasome via the MALAT1?miR?22?3p signaling pathway.
Surfactant protein D gene regulation. Interactions among the conserved CCAAT/enhancer-binding protein elements.
The transcriptional factor YY1 upregulates the novel invasion suppressor HLJ1 expression and inhibits cancer cell invasion.
Transcriptional targeting of adenovirus vectors with the squamous cell carcinoma-specific antigen-2 promoter for selective apoptosis induction in lung cancer.
Weekly osimertinib dosing prevents EGFR mutant tumor cells destined to home mouse lungs.
[Effects of microRNA-146a on Fas-associated factor 2 and inflammatory factors in human lung adenocarcinoma A549 cells under the stimulation of cigarette smoke extract].
[Establishment of the cell line that human lung adenocarcinoma can stably express luciferase which is absent of nm23-H1 expression and detecting its luminescence?in vitro and in vivo].
Adenocarcinoma, Bronchiolo-Alveolar
Oxygen-evoked changes in transcriptional activity of the 5'-flanking region of the human amiloride-sensitive sodium channel (alphaENaC) gene: role of nuclear factor kappaB.
Adenoma
Aberrant methylation of the CDH13 (H-cadherin) promoter region in colorectal cancers and adenomas.
Function and characterization of the promoter region of perilipin 1 (PLIN1): Roles of E2F1, PLAG1, C/EBP?, and SMAD3 in bovine adipocytes.
Relative differences in aryl hydrocarbon receptor-mediated response for 18 polybrominated and mixed halogenated dibenzo-p-dioxins and -furans in cell lines from four different species.
The PLAGL2/MYCN/miR-506-3p interplay regulates neuroblastoma cell fate and associates with neuroblastoma progression.
Adenomatous Polyposis Coli
Long non-coding RNA miR143HG predicts good prognosis and inhibits tumor multiplication and metastasis by suppressing mitogen-activated protein kinase and Wnt signaling pathways in hepatocellular carcinoma.
MiR-205 mediated APC regulation contributes to pancreatic cancer cell proliferation.
Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity.
[miR-182 promotes cell proliferation of cervical cancer cells by targeting adenomatous polyposis coli (APC) gene].
Adenoviridae Infections
Activation of NF-kappaB following detachment delays apoptosis in intestinal epithelial cells.
Noninvasive imaging of transcriptionally restricted transgene expression following intratumoral injection of an adenovirus in which the COX-2 promoter drives a reporter gene.
Protein kinase CK2? catalytic subunit ameliorates diabetic renal inflammatory fibrosis via NF-?B signaling pathway.
The LIM homeodomain protein ISL1 mediates the function of TCF7L2 in pancreatic beta cells.
TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death.
Adrenocortical Carcinoma
Clinical and molecular evidence for DAX-1 inhibition of steroidogenic factor-1-dependent ACTH receptor gene expression.
PCP4: a regulator of aldosterone synthesis in human adrenocortical tissues.
African Swine Fever
A Semiautomated Luciferase Immunoprecipitation Assay for Rapid and Easy Detection of African Swine Fever Virus Antibody.
Albinism, Oculocutaneous
Intravitreal administration of small molecule read-through agents demonstrate functional activity in a nonsense mutation mouse model.
Alopecia
Inducible, reversible hair loss in transgenic mice.
Alzheimer Disease
Activating transcription factor 6 reduces A?1-42 and restores memory in Alzheimer's disease model mice.
Amyotrophic Lateral Sclerosis
Dynamics of host and graft after cell sheet transplantation: Basic study for the application of amyotrophic lateral sclerosis.
Anaplasmosis
Discovery, adaptation and transcriptional activity of two tick promoters: Construction of a dual luciferase reporter system for optimization of RNA interference in rhipicephalus (boophilus) microplus cell lines.
Androgen-Insensitivity Syndrome
The adenovirus-mediated delivery of a reporter gene permits the assessment of androgen receptor function in genital skin fibroblast cultures. Stimulation of Gs and inhibition of G(o).
Anemia
Differential HIF and NOS responses to acute anemia: defining organ-specific hemoglobin thresholds for tissue hypoxia.
Real-time monitoring of stress erythropoiesis in vivo using Gata1 and beta-globin LCR luciferase transgenic mice.
Aneurysm
LncRNA H19 promotes vascular inflammation and abdominal aortic aneurysm formation by functioning as a competing endogenous RNA.
Anthrax
Effective delivery of antisense peptide nucleic acid oligomers into cells by anthrax protective antigen.
Aortic Aneurysm
Inactivation of SERCA2 Cys674 accelerates aortic aneurysms by suppressing PPAR?.
Arthritis
A novel Saa3-promoter reporter distinguishes inflammatory subtypes in experimental arthritis and human synovial fibroblasts.
Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees.
Antinociceptive and anti-in?ammatory activities of Copaifera pubiflora Benth oleoresin and its major metabolite ent-hardwickiic acid.
Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in transgenic mice.
Treatment of autoimmune disease by adoptive cellular gene therapy.
Arthritis, Experimental
The effect of promoter strength in adenoviral vectors in hyperplastic synovium.
Arthritis, Rheumatoid
A novel Saa3-promoter reporter distinguishes inflammatory subtypes in experimental arthritis and human synovial fibroblasts.
Asthma
Association Study of Myosin Heavy Chain 15 Polymorphisms with Asthma Susceptibility in Chinese Han.
Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages.
LncRNA NEAT1 promotes airway smooth muscle cell inflammation by activating the JAK3/STAT5 pathway through targeting of miR-139.
MicroRNA-34/449 targets IGFBP-3 and attenuates airway remodeling by suppressing Nur77-mediated autophagy.
Upregulation of microRNA?16 alters the response to inhaled ??agonists in patients with asthma though modulating expression of ADRB2.
Astrocytoma
A novel approach for examining the anti-proliferative effect of protein kinase C inhibitors against human astrocytoma cells.
Cloning of the rat fibroblast growth factor-2 promoter region and its response to mitogenic stimuli in glioma C6 cells.
Constitutive expression of human immunodeficiency virus (HIV) nef protein in human astrocytes does not influence basal or induced HIV long terminal repeat activity.
Gene structure of the human metabotropic glutamate receptor 5 and functional analysis of its multiple promoters in neuroblastoma and astroglioma cells.
New reporter cell line to evaluate the sequential emergence of multiple human cytomegalovirus mutations during in vitro drug exposure.
Ataxia Telangiectasia
?-Radiation induces cellular sensitivity and aberrant methylation in human tumor cell lines.
Identification of Lethal microRNAs Specific for Head and Neck Cancer.
r-Tocotrienol inhibits cell proliferation of human gastric cancer by regulating nuclear factor-kB activity.
Radiosensitizing effects of miR-18a-5p on lung cancer stem-like cells via downregulating both ATM and HIF-1?.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Tumor suppressor function of miR-483-3p on breast cancer via targeting of the cyclin E1 gene.
Atherosclerosis
Characterization of Partial Ligation-Induced Carotid Atherosclerosis Model Using Dual-Modality Molecular Imaging in ApoE Knock-out Mice.
Hsa_circRNA_102541 regulates the development of atherosclerosis by targeting miR-296-5p/PLK1 pathway.
Long noncoding RNA SNHG14 regulates ox-LDL-induced atherosclerosis cell proliferation and apoptosis by targeting miR-186-5p/WIPF2 axis.
MicroRNA-24 aggravates atherosclerosis by inhibiting selective lipid uptake from HDL cholesterol via the post-transcriptional repression of scavenger receptor class B type I.
MicroRNA-34c suppresses proliferation of vascular smooth muscle cell via modulating high mobility group box protein 1.
MiR-182-5p Inhibits the Proliferation of Vascular Smooth Muscle Cells Induced by ox-LDL Through Targeting PAPPA.
miR-454-3p prevents ox-LDL-induced apoptosis in HAECs by targeting TRPC3.
Resveratrol Derivative, Trans-3, 5, 4'-Trimethoxystilbene, Prevents the Developing of Atherosclerotic Lesions and Attenuates Cholesterol Accumulation in Macrophage Foam Cells.
[Construction and identification of recombinant firefly luciferase report vector containing human acyl coenzyme a: cholesterol acyltransferase 1 gene P7 promoter]
Autoimmune Diseases
Adoptive cellular gene therapy of autoimmune disease.
Ganglionic Acetylcholine Receptor Antibodies and Autonomic Dysfunction in Autoimmune Rheumatic Diseases.
Identification of Tetraazacyclic Compounds as Novel Potent Inhibitors Antagonizing ROR?t Activity and Suppressing Th17 Cell Differentiation.
Salivary anti-Ro60 and anti-Ro52 Antibody Profiles to Diagnose Sjogren's Syndrome.
TH1 and TH2 cytokine inhibition by 3,5-bis(trifluoromethyl)pyrazoles, a novel class of immunomodulators.
Babesiosis
Characterization of a Monanema nematode in Ixodes scapularis.
Discovery, adaptation and transcriptional activity of two tick promoters: Construction of a dual luciferase reporter system for optimization of RNA interference in rhipicephalus (boophilus) microplus cell lines.
Bacterial Infections
Activation of COL1A2 promoter in human fibroblasts by Escherichia coli.
Bovine serum amyloid A3 gene structure and promoter analysis: Induced transcriptional expression by bacterial components and the hormone prolactin.
Evaluation of Ralstonia solanacearum Infection Dynamics in Resistant and Susceptible Pepper Lines Using Bioluminescence Imaging.
Non-Invasive Luciferase Imaging of Type I Interferon Induction in a Transgenic Mouse Model of Biomaterial Associated Bacterial Infections: Microbial Specificity and Inter-Bacterial Species Interactions.
Using luciferase to image bacterial infections in mice.
Bacteriuria
Analysis of the disagreement between automated bioluminescence-based and culture methods for detecting significant bacteriuria, with proposals for standardizing evaluations of bacteriuria detection methods.
Detection of bacteriuria by luciferase assay of adenosine triphosphate.
Evaluation of an adenosine 5'-triphosphate assay as a screening method to detect significant bacteriuria.
Barrett Esophagus
Dysfunctional transforming growth factor-? signaling with constitutively active notch signaling in Barrett's esophageal Adenocarcinoma.
Bicuspid Aortic Valve Disease
The stretch responsive microRNA miR-148a-3p is a novel repressor of IKBKB, NF-?B signaling, and inflammatory gene expression in human aortic valve cells.
Bone Neoplasms
miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis.
miRNA-128 modulates bone neoplasms cells proliferation and migration through the WNT/?-catenin and EMT signal pathways.
Bone Resorption
Abrogation of prostaglandin E-EP4 signaling in osteoblasts prevents the bone destruction induced by human prostate cancer metastases.
Ellagic acid protects ovariectomy-induced bone loss in mice by inhibiting osteoclast differentiation and bone resorption.
Estrogen inhibits osteoclasts formation and bone resorption via microRNA-27a targeting PPAR? and APC.
In vivo imaging of particle-induced inflammation and osteolysis in the calvariae of NF?B/luciferase transgenic mice.
Triptolide inhibits osteoclast formation, bone resorption, RANKL-mediated NF-?B activation and titanium particle-induced osteolysis in a mouse model.
Border Disease
Development of a High-Throughput Serum Neutralization Test Using Recombinant Pestiviruses Possessing a Small Reporter Tag.
Brain Injuries
Use of Tethered Enzymes as a Platform Technology for Rapid Analyte Detection.
Brain Ischemia
Live imaging of neuroinflammation reveals sex and estrogen effects on astrocyte response to ischemic injury.
MicroRNA-9a-5p Alleviates Ischemia Injury After Focal Cerebral Ischemia of the Rat by Targeting ATG5-Mediated Autophagy.
Sequential activation of hypoxia-inducible factor 1 and specificity protein 1 is required for hypoxia-induced transcriptional stimulation of Abcc8.
Brain Neoplasms
Antisense imaging of gene expression in the brain in vivo.
Biotinylated Bioluminescent Probe for Long Lasting Targeted in Vivo Imaging of Xenografted Brain Tumors in Mice.
Detection of Brain Tumors and Systemic Metastases Using NanoLuc and Fluc for Dual Reporter Imaging.
Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies.
In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats.
Intravenous siRNA of brain cancer with receptor targeting and avidin-biotin technology.
Rat model of metastatic breast cancer monitored by MRI at 3 tesla and bioluminescence imaging with histological correlation.
RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model.
The brain microenvironment negatively regulates miRNA-768-3p to promote K-ras expression and lung cancer metastasis.
Time course of bioluminescent signal in orthotopic and heterotopic brain tumors in nude mice.
Breast Neoplasms
(4R,5S)/(4S,5R)-4,5-Bis(4-hydroxyphenyl)-2-imidazolines: ligands for the estrogen receptor with a novel binding mode.
2,5-Diphenylfuran-based pure antiestrogens with selectivity for the estrogen receptor alpha.
3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen.
A Bis-Indole-Derived NR4A1 Antagonist Induces PD-L1 Degradation and Enhances Antitumor Immunity.
A Bmi1-miRNAs Cross-Talk Modulates Chemotherapy Response to 5-Fluorouracil in Breast Cancer Cells.
A CXCR4 antagonist CTCE-9908 inhibits primary tumor growth and metastasis of breast cancer.
A functional -77T>C polymorphism in XRCC1 is associated with risk of breast cancer.
A ginsenoside-Rh1, a component of ginseng saponin, activates estrogen receptor in human breast carcinoma MCF-7 cells.
A High-Content Assay to Identify Small-Molecule Modulators of a Cancer Stem Cell Population in Luminal Breast Cancer.
A highly sensitive method for large-scale measurements of 1,25-dihydroxyvitamin D.
A minimum c-erbB-2 promoter-mediated expression of herpes simplex virus thymidine kinase gene confers selective cytotoxicity of human breast cancer cells to ganciclovir.
A novel reduced immunogenicity bispecific targeted toxin simultaneously recognizing human epidermal growth factor and interleukin-4 receptors in a mouse model of metastatic breast carcinoma.
A potent, imaging adenoviral vector driven by the cancer-selective mucin-1 promoter that targets breast cancer metastasis.
A rapid luciferase transfection assay for transcription activation effects and stability control of estrogenic drugs in cell cultures.
A specific peptide ligand-modified lipid nanoparticle carrier for the inhibition of tumor metastasis growth.
A stat-responsive element in the promoter of the episialin/MUC1 gene is involved in its overexpression in carcinoma cells.
A synthetic chalcone as a potent inducer of glutathione biosynthesis.
A synthetic peptide with estrogen-like activity derived from a phage-display peptide library.
Activation of brain estrogen receptors in mice lactating from mothers exposed to DDT.
Activation of rapid signaling pathways and the subsequent transcriptional regulation for the proliferation of breast cancer MCF-7 cells by the treatment with an extract of Glycyrrhiza glabra root.
Activity of benzo[a]pyrene and its hydroxylated metabolites in an estrogen receptor-alpha reporter gene assay.
AFF3 upregulation mediates tamoxifen resistance in breast cancers.
Ah receptor and estrogen receptor-dependent modulation of gene expression by extracts of diesel exhaust particles.
Akt1 inhibition promotes breast cancer metastasis through EGFR-mediated ?-catenin nuclear accumulation.
An Activin A/BMP2 chimera, AB215, blocks estrogen signaling via induction of ID proteins in breast cancer cells.
Analysis of ZNF350/ZBRK1 promoter variants and breast cancer susceptibility in non-BRCA1/2 French Canadian breast cancer families.
Angiotensin II promotes primary tumor growth and metastasis formation of murine TNBC 4T1 cells through the fibroblasts around cancer cells.
Anti-inflammatory and anticancer activities of extracts and compounds from the mushroom Inonotus obliquus.
Antiestrogenic and DNA damaging effects induced by tamoxifen and toremifene metabolites.
Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis.
Application of ultrasonic gas-filled liposomes in enhancing transfer for breast cancer-related antisense oligonucleotides: an experimental study.
AroER Tri-Screen Is a Biologically Relevant Assay for Endocrine Disrupting Chemicals Modulating the Activity of Aromatase and/or the Estrogen Receptor.
AroER tri-screen™ is a novel functional assay to estimate both estrogenic and estrogen precursor activity of chemicals or biological specimens.
Arsenic induces functional re-expression of estrogen receptor ? by demethylation of DNA in estrogen receptor-negative human breast cancer.
Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah-responsiveness in MCF-7 and HepG2 cancer cells.
Assessment of styrene oligomers eluted from polystyrene-made food containers for estrogenic effects in in vitro assays.
Association of lifestyle and demographic factors with estrogenic and glucocorticogenic activity in Mexican American women.
Bioluminescence in drug development for cancer: Shedding light on therapeutic efficacy.
Bioluminescence Tomography Guided Small-Animal Radiation Therapy and Tumor Response Assessment.
Breast cancer metastasis to bone: evaluation of bioluminescent imaging and microSPECT/CT for detecting bone metastasis in immunodeficient mice.
Breast cancer stem-like cells are sensitized to tamoxifen induction of self-renewal inhibition with enforced Let-7c dependent on Wnt blocking.
Breast cancer-specific TRAIL expression mediated by miRNA response elements of let-7 and miR-122.
cAMP responsive element binding protein-1 is a transcription factor of lysosomal-associated protein transmembrane-4 Beta in human breast cancer cells.
Cancer-Associated Fibroblasts-Derived Exosomes Suppress Immune Cell Function in Breast Cancer via the miR-92/PD-L1 Pathway.
Cell-Based Bioassay to Screen Environmental Chemicals and Human Serum for Total Glucocorticogenic Activity.
Characterization of a new class of selective nonsteroidal progesterone receptor agonists.
Characterization of a point mutation in the hormone binding domain of the estrogen receptor from an breast tumor.
Characterization of long-circulating cationic nanoparticle formulations consisting of a two-stage PEGylation step for the delivery of siRNA in a breast cancer tumor model.
Characterization of the 5'-flanking region of the human PTK6 gene.
Characterization of the androgen-sensitive MDA-kb2 cell line for assessing complex environmental mixtures.
Characterization of transcription factors and cis-acting elements that regulate human CTP: phosphoethanolamine cytidylyltransferase (Pcyt2).
Chelerythrine down regulates expression of VEGFA, BCL2 and KRAS by arresting G-Quadruplex structures at their promoter regions.
Chicken ovalbumin upstream promoter-transcription factor interacts with estrogen receptor, binds to estrogen response elements and half-sites, and inhibits estrogen-induced gene expression.
Circ-DENND4C up-regulates TCF4 expression to modulate hepatocellular carcinoma cell proliferation and apoptosis via activating Wnt/?-catenin signal pathway.
Circular RNA hsa_circ_0052112 promotes cell migration and invasion by acting as sponge for miR-125a-5p in breast cancer.
Circular RNA hsa_circ_0072995 promotes breast cancer cell migration and invasion through sponge for miR-30c-2-3p.
Circ_0001667 promotes breast cancer cell proliferation and survival via Hippo signal pathway by regulating TAZ.
Click assembly of magnetic nanovectors for gene delivery.
Cloning and characterization of the promoter region of the bovine membrane tethering protein p115 gene and its regulation in mammary epithelial cells.
Combination of Radiofrequency Ablation and Glycated Chitosan as Treatment on a Syngeneic Breast Tumor Model.
Comparative estrogenic activity of wine extracts and organochlorine pesticide residues in food.
Comparison of an array of in vitro assays for the assessment of the estrogenic potential of natural and synthetic estrogens, phytoestrogens and xenoestrogens.
Comparison of in vivo and in vitro reporter gene assays for short-term screening of estrogenic activity.
Comparison of three different methods for the detection of circulating tumor cells in mice with lung metastasis.
Comparison of transfection efficiency of nonviral gene transfer reagents.
Complexation of Chol-DsiRNA in place of Chol-siRNA greatly increases the duration of mRNA suppression by polyplexes of PLL(30)-PEG(5K) in primary murine syngeneic breast tumors after i.v. administration.
CONSORT: Sam68 Is Directly Regulated by MiR-204 and Promotes the Self-Renewal Potential of Breast Cancer Cells by Activating the Wnt/Beta-Catenin Signaling Pathway.
Construction of an initial microRNA regulation network in breast invasive carcinoma by bioinformatics analysis.
Core - shell upconversion nanoparticle - semiconductor heterostructures for photodynamic therapy.
COX-2 involvement in breast cancer metastasis to bone.
Currently used pesticides and their mixtures affect the function of sex hormone receptors and aromatase enzyme activity.
Decreased expression of microRNA-17 and microRNA-20b promotes breast cancer resistance to taxol therapy by upregulation of NCOA3.
Decreased microRNA-768-3p expression indicates a poor prognosis in patients with breast cancer and promotes breast cancer cell viability, migration and invasion.
Defining the therapeutic window of vertebral photodynamic therapy in a murine pre-clinical model of breast cancer metastasis using the photosensitizer BPD-MA (Verteporfin).
Delivery of epirubicin via slow infusion as a strategy to mitigate chemotherapy-induced cardiotoxicity.
Dendrons with spermine surface groups as potential building blocks for nonviral vectors in gene therapy.
Deoxybenzoins are novel potent selective estrogen receptor modulators.
Development and validation of non-integrative, self-limited, and replicating minicircles for safe reporter gene imaging of cell-based therapies.
Development of a cell-based bioassay for phospholipase A2-triggered liposomal drug release.
Development of a destabilized firefly luciferase enzyme for measurement of gene expression.
Development of a Novel Anti-HIF-1? Screening System Coupled with Biochemical and Biological Validation for Rapidly Selecting Potent Anti-Cancer Compounds.
Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line.
Development of an androgen reporter gene assay (AR-LUX) utilizing a human cell line with an endogenously regulated androgen receptor.
Development of two androgen receptor assays using adenoviral transduction of MMTV-luc reporter and/or hAR for endocrine screening.
DHA is a more potent inhibitor of breast cancer metastasis to bone and related osteolysis than EPA.
Dietary soy isoflavones increase metastasis to lungs in an experimental model of breast cancer with bone micro-tumors.
Differential 12-O-Tetradecanoylphorbol-13-acetate-induced activation of rat mammary carcinoma susceptibility Fbxo10 variant promoters via a PKC-AP1 pathway.
Differential protein expression in MCF7 breast cancer cells transfected with ErbB2, neomycin resistance and luciferase plus yellow fluorescent protein.
Direct activation of oestrogen receptor-alpha by interleukin-6 in primary cultures of breast cancer epithelial cells.
Dose-Dependent Growth Delay of Breast Cancer Xenografts in the Bone Marrow of Mice Treated with Radium-223: The Role of Bystander Effects and their Potential for Therapy.
Down-regulation of MicroRNAs (MiRs) 203, 887, 3619 and 182 Prevents Vimentin-triggered, Phospholipase D (PLD)-mediated Cancer Cell Invasion.
Downregulation of GSK3B by miR-132-3p Enhances Etoposide-Induced Breast Cancer Cell Apoptosis.
Downregulation of MicroRNA-152 and Inhibition of Cell Proliferation, Migration, and Invasion in Breast Cancer.
Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor??B signaling pathway.
Effective treatment of human breast tumor in a mouse xenograft model with herpes simplex virus type 1 specifying the NV1020 genomic deletion and the gBsyn3 syncytial mutation enabling high viral replication and spread in breast cancer cells.
Effects of C2-alkylation, N-alkylation, and N,N'-dialkylation on the stability and estrogen receptor interaction of (4R,5S)/(4S,5R)-4,5-bis(4-hydroxyphenyl)-2-imidazolines.
Effects of MiR-107 on The Chemo-drug Sensitivity of Breast Cancer Cells.
EGF activates highly selective estrogen-responsive reporter plasmids by an ER-independent pathway.
Electrophoretic mobility shift assays implicate XRCC2:rs3218550C>T as a potential low-penetrant susceptibility allele for sporadic breast cancer.
Enhanced gene delivery to HER-2-overexpressing breast cancer cells by modified immunolipoplexes conjugated with the anti-HER-2 antibody.
Epimedin C Promotes Vascularization during BMP2-Induced Osteogenesis and Tumor-Associated Angiogenesis.
Establishment and evaluation of a new highly metastatic tumor cell line 5a-D-Luc-ZsGreen expressing both luciferase and green fluorescent protein.
Establishment of a Human Breast Cancer Model by Fusion PCR for In Vivo and In Vitro Fluorescence Imaging of Human Breast Cancer.
Estradiol enhances liposome-mediated uptake, preferential nuclear accumulation and functional expression of exogenous genes in MDA-MB231 breast tumor cells.
Estrogen-induced aurora kinase-A (AURKA) gene expression is activated by GATA-3 in estrogen receptor-positive breast cancer cells.
Estrogenic activity of estradiol and its metabolites in the ER-CALUX assay with human T47D breast cells.
Evaluation of anti-tumor effects following tumor necrosis factor-? gene delivery using nanobubbles and ultrasound.
Evaluation of the combined use of metronomic zoledronic acid and Coriolus versicolor in intratibial breast cancer mouse model.
Examination of the estrogenicity of 2,4,6,2',6'-pentachlorobiphenyl (PCB 104), its hydroxylated metabolite 2,4,6,2',6'-pentachloro-4-biphenylol (HO-PCB 104), and a further chlorinated derivative, 2,4,6,2',4',6'-hexachlorobiphenyl (PCB 155).
Exon-intron structure of the human PTK6 gene demonstrates that PTK6 constitutes a distinct family of non-receptor tyrosine kinase.
Extensive transcriptional complexity during hypoxia-regulated expression of the myoglobin gene in cancer.
Factors regulating pS2-reporter gene expression in MCF-7 breast cancer cell line.
FcRn overexpression in human cancer drives albumin recycling and cell growth; a mechanistic basis for exploitation in targeted albumin-drug designs.
Flavonoids from the heartwood of the Thai medicinal plant Dalbergia parviflora and their effects on estrogenic-responsive human breast cancer cells.
FOSL2 promotes VEGF-independent angiogenesis by transcriptionnally activating Wnt5a in breast cancer-associated fibroblasts.
Functional and physical interactions between BRCA1 and p53 in transcriptional regulation of the IGF-IR gene.
Functional Variants at the 11q13 Risk Locus for Breast Cancer Regulate Cyclin D1 Expression through Long-Range Enhancers.
Fungal substances as modulators of NF-kappaB activation pathway.
GDF15 serves as a co-activator to enhance KISS-1 gene transcription through interacting with Sp1.
Generation of stable reporter breast cancer cell lines for the identification of ER subtype selective ligands.
Genetic and epigenetic regulation of AHR gene expression in MCF-7 breast cancer cells: Role of the proximal promoter GC-rich region.
Genome-wide target interactome profiling reveals a novel EEF1A1 epigenetic pathway for oncogenic lncRNA MALAT1 in breast cancer.
Ginsenoside-Rb1 acts as a weak phytoestrogen in MCF-7 human breast cancer cells.
Glutamate metabotropic receptor 4 (GRM4) inhibits cell proliferation, migration and invasion in breast cancer and is regulated by miR-328-3p and miR-370-3p.
Glycogen synthase kinase-3 protects estrogen receptor alpha from proteasomal degradation and is required for full transcriptional activity of the receptor.
GPER Mediates Non-Genomic Effects of Estrogen.
H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b.
HDAC3-ER? Selectively Regulates TNF-?-Induced Apoptotic Cell Death in MCF-7 Human Breast Cancer Cells via the p53 Signaling Pathway.
HER2-intronic miR-4728-5p facilitates HER2 expression and accelerates cell proliferation and migration by targeting EBP1 in breast cancer.
High-throughput screen of natural product libraries for hsp90 inhibitors.
Hydrophobic oxime ethers: a versatile class of pDNA and siRNA transfection lipids.
Hydroxylated polychlorinated biphenyls (PCBs) as estrogens and antiestrogens: structure-activity relationships.
Identification and characterization of the retinoic acid response elements in the human RIG1 gene promoter.
Identification of environmental chemicals with estrogenic activity using a combination of in vitro assays.
Identification of novel small-molecule inhibitors of hypoxia-inducible factor-1 transactivation and DNA binding.
Imaging of luciferase and GFP-transfected human tumours in nude mice.
Impaired 11?-Hydroxysteroid Dehydrogenase Type 2 in Glucocorticoid Resistant Patients.
In vitro estrogenicity of polybrominated diphenyl ethers, hydroxylated PDBEs, and polybrominated bisphenol A compounds.
In vivo and in vitro estrogenic activity of the antidepressant fluoxetine.
In vivo bioluminescence imaging monitoring of hypoxia-inducible factor 1alpha, a promoter that protects cells, in response to chemotherapy.
In Vivo Photoactivation Without "Light": Use of Cherenkov Radiation to Overcome the Penetration Limit of Light.
In vivo profiling of estrogen receptor/specificity protein-dependent transactivation.
Increased expression of MUSASHI1 in epithelial breast cancer cells is due to down regulation of miR-125b.
Induction of androgen receptor activity by norgestimate and norelgestromin in MDA-MB 231 breast cancer cells.
Inhibition of estrogen signaling activates the NRF2 pathway in breast cancer.
Inhibition of MDA-MB-231 breast cancer cell migration and invasion activity by andrographolide via suppression of nuclear factor-?B-dependent matrix metalloproteinase-9 expression.
Inhibition of metastatic tumor formation in vivo by a bacteriophage display-derived galectin-3 targeting peptide.
Inhibition of murine breast cancer growth and metastasis by survivin-targeted siRNA using disulfide cross-linked linear PEI.
Interfering cellular lactate homeostasis overcomes Taxol resistance of breast cancer cells through the microRNA-124-mediated lactate transporter (MCT1) inhibition.
Invesgations [correction investigations] on the influence of halide substituents on the estrogen receptor interaction of 2, 4, 5-tris(4-hydroxyphenyl)imidazoles.
Involved microRNAs in alternative polyadenylation intervene in breast cancer via regulation of cleavage factor "CFIm25".
Involvement of miR-30c in resistance to doxorubicin by regulating YWHAZ in breast cancer cells.
iRGD-guided tamoxifen polymersomes inhibit estrogen receptor transcriptional activity and decrease the number of breast cancer cells with self-renewing capacity.
Janus kinase 2--a novel negative regulator of estrogen receptor ? function.
Let-7a mimic attenuates CCL18 induced breast cancer cell metastasis through Lin 28 pathway.
Ligand structure-dependent activation of estrogen receptor alpha/Sp by estrogens and xenoestrogens.
LINC00346 regulates glycolysis by modulation of glucose transporter 1 in breast cancer cells.
Linc00514 promotes breast cancer metastasis and M2 polarization of tumor-associated macrophages via Jagged1-mediated notch signaling pathway.
Linc00518 Contributes to Multidrug Resistance Through Regulating the MiR-199a/MRP1 Axis in Breast Cancer.
lncRNA CYTOR promotes tamoxifen resistance in breast cancer cells via sponging miR?125a?5p.
LncRNA HOTAIR promotes breast cancer progression through regulating the miR-129-5p/FZD7 axis.
LncRNA LOXL1-AS1 inhibited cell proliferation, migration and invasion as well as induced apoptosis in breast cancer via regulating miR-143-3p.
LncRNA LUCAT1/miR-181a-5p axis promotes proliferation and invasion of breast cancer via targeting KLF6 and KLF15.
LncRNA MEG3 inhibits cell epithelial-mesenchymal transition by sponging miR-421 targeting E-cadherin in breast cancer.
lncRNA PCNAP1 predicts poor prognosis in breast cancer and promotes cancer metastasis via miR?340?5p?dependent upregulation of SOX4.
Long non-coding RNA A1BG-AS1 promotes tumorigenesis in breast cancer by sponging microRNA-485-5p and consequently increasing expression of FLOT1 expression.
Long non-coding RNA FTH1P3 activates paclitaxel resistance in breast cancer through miR-206/ABCB1.
Long non-coding RNA Tubulin Alpha 4B (TUBA4B) inhibited breast cancer proliferation and invasion by directly targeting miR-19.
Long non-coding RNA XIST inhibited breast cancer cell growth, migration, and invasion via miR-155/CDX1 axis.
Loss of Hypermethylated in Cancer 1 (HIC1) in Breast Cancer Cells Contributes to Stress-induced Migration and Invasion through ?-2 Adrenergic Receptor (ADRB2) Misregulation.
Luciferase Expression Allows Bioluminescence Imaging But Imposes Limitations on the Orthotopic Mouse (4T1) Model of Breast Cancer.
Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo.
Measurement of estrogenic activity in sediments from Haihe and Dagu River, China.
Melatonin inhibits estrogen receptor transactivation and cAMP levels in breast cancer cells.
Melatonin inhibits mitogenic cross-talk between retinoic acid-related orphan receptor alpha (RORalpha) and ERalpha in MCF-7 human breast cancer cells.
Metastasis of Breast Tumor Cells to Brain Is Suppressed by Phenethyl Isothiocyanate in a Novel In Vivo Metastasis Model.
Metastasis of breast tumor cells to brain is suppressed by targeting RLIP alone and in combination with 2'-Hydroxyflavanone.
Metastatic behavior of human breast carcinomas overexpressing the Bcl-x(L) gene: a role in dormancy and organospecificity.
Metformin alleviates breast cancer through targeting high-mobility group AT-hook 2.
Methodologies for the establishment of an orthotopic transplantation model of ovarian cancer in mice.
Methods for culturing human femur tissue explants to study breast cancer cell colonization of the metastatic niche.
MHP-1 inhibits cancer metastasis and restores topotecan sensitivity via regulating epithelial-mesenchymal transition and TGF-? signaling in human breast cancer cells.
Microparticle Depots for Controlled and Sustained Release of Endosomolytic Nanoparticles.
MicroRNA-124 inhibits cell proliferation and migration by regulating SNAI2 in breast cancer.
MicroRNA-125a-5p inhibits invasion and metastasis of gastric cancer cells by targeting BRMS1 expression.
MicroRNA-125b as a tumor suppressor by targeting MMP11 in breast cancer.
MicroRNA-132 suppresses cell proliferation in human breast cancer by directly targeting FOXA1.
MicroRNA-133a acts as a tumour suppressor in breast cancer through targeting LASP1.
MicroRNA-134 targets KRAS to suppress breast cancer cell proliferation, migration and invasion.
microRNA-152 inhibits cell proliferation, migration and invasion in breast cancer.
MicroRNA-153 inhibits cell proliferation, migration, invasion and epithelial-mesenchymal transition in breast cancer via direct targeting of RUNX2.
MicroRNA-193a inhibits breast cancer proliferation and metastasis by downregulating WT1.
MicroRNA-205 inhibits the proliferation and invasion of breast cancer by regulating AMOT expression.
MicroRNA-21 regulates breast cancer invasion partly by targeting tissue inhibitor of metalloproteinase 3 expression.
microRNA-370 Promotes Cell Growth by Targeting WNK2 in Breast Cancer.
MicroRNA-384 inhibits the progression of breast cancer by targeting ACVR1.
MicroRNA-497 downregulation contributes to cell proliferation, migration, and invasion of estrogen receptor alpha negative breast cancer by targeting estrogen-related receptor alpha.
MicroRNA-7 suppresses the homing and migration potential of human endothelial cells to highly metastatic human breast cancer cells.
MicroRNA-876 is sponged by long noncoding RNA LINC00707 and directly targets metadherin to inhibit breast cancer malignancy.
MicroRNA-99a Suppresses Breast Cancer Progression by Targeting FGFR3.
MicroRNA?124 suppresses cell proliferation and invasion of triple negative breast cancer cells by targeting STAT3.
miR-1296-5p decreases ERBB2 expression to inhibit the cell proliferation in ERBB2-positive breast cancer.
Mir-1307 regulates cisplatin resistance by targeting Mdm4 in breast cancer expressing wild type P53.
MiR-139-5p inhibits the biological function of breast cancer cells by targeting Notch1 and mediates chemosensitivity to docetaxel.
miR-142-3p is a tumor suppressor that inhibits estrogen receptor expression in ER-positive breast cancer.
miR-145-dependent targeting of Junctional Adhesion Molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness.
miR-146a promoted breast cancer proliferation and invasion by regulating NM23-H1.
miR-15a/miR-16 induces mitochondrial dependent apoptosis in breast cancer cells by suppressing oncogene BMI1.
miR-15b-5p Promotes Growth and Metastasis in Breast Cancer by Targeting HPSE2.
miR-187-3p increases gemcitabine sensitivity in breast cancer cells by targeting FGF9 expression.
miR-205-5p downregulation decreases gemcitabine sensitivity of breast cancer cells via ERp29 upregulation.
miR-22 suppresses tumorigenesis and improves radiosensitivity of breast cancer cells by targeting Sirt1.
miR-30a inhibits the biological function of breast cancer cells by targeting Notch1.
MiR-346 promotes HCC progression by suppressing Breast cancer metastasis suppressor 1 expression.
miR-346 promotes migration and invasion of nasopharyngeal carcinoma cells via targeting BRMS1.
miR-376a inhibits breast cancer cell progression by targeting neuropilin-1 NR.
miR-381 overcomes cisplatin resistance in breast cancer by targeting MDR1.
miR-448 inhibits the epithelial-mesenchymal transition in breast cancer cells by directly targeting the E-cadherin repressor ZEB1/2.
MiR-454-3p-Mediated Wnt/?-catenin Signaling Antagonists Suppression Promotes Breast Cancer Metastasis.
miR-493-5p attenuates the invasiveness and tumorigenicity in human breast cancer by targeting FUT4.
miR-511 inhibits proliferation and metastasis of breast cancer cells by targeting FGF4.
miR-615-3p promotes the epithelial-mesenchymal transition and metastasis of breast cancer by targeting PICK1/TGFBRI axis.
miR-622 is a novel potential biomarker of breast carcinoma and impairs motility of breast cancer cells through targeting NUAK1 kinase.
MiR-99a suppress proliferation, migration and invasion through regulating insulin-like growth factor 1 receptor in breast cancer.
miRNA-192-5p impacts the sensitivity of breast cancer cells to doxorubicin via targeting peptidylprolyl isomerase A.
miRNA-215-5p suppresses the aggressiveness of breast cancer cells by targeting Sox9.
miRNA-411 acts as a potential tumor suppressor miRNA via the downregulation of specificity protein 1 in breast cancer.
Modulation of human stromelysin 3 promoter activity and gene expression by human breast cancer cells.
Molecular structure of the human gonadotropin-releasing hormone receptor gene.
Notch1 signaling regulates the epithelial¿mesenchymal transition and invasion of breast cancer in a Slug-dependent manner.
Novel mouse mammary cell lines for in vivo bioluminescence imaging (BLI) of bone metastasis.
Oncogenic microRNA-765 promotes the growth and metastasis of breast carcinoma by directly targeting ING4.
Optimization of an estrogen receptor-alpha transcriptional activation assay for testing a diverse spectrum of chemicals.
Overexpression miR-24-3p repressed Bim expression to confer tamoxifen resistance in breast cancer.
Overexpression of miR-3196 suppresses cell proliferation and induces cell apoptosis through targeting ERBB3 in breast cancer.
p53 activation in chronic radiation-treated breast cancer cells: regulation of MDM2/p14ARF.
p53-Independent expression of wild-type p53-induced phosphatase 1 (Wip1) in methylmethane sulfonate-treated cancer cell lines and human tumors.
Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro.
Periodic Mesoporous Ionosilica Nanoparticles for Green Light Photodynamic Therapy and Photochemical Internalization of siRNA.
Pharmacogenetic heterogeneity of transgene expression in muscle and tumours.
Pharmacologic inhibition of bone resorption prevents cancer-induced osteolysis but enhances soft tissue metastasis in a mouse model of osteolytic breast cancer.
Physical activity modulates mononuclear phagocytes in mammary tissue and inhibits tumor growth in mice.
Phytoestrogen regulation of a Vitamin D3 receptor promoter and 1,25-dihydroxyvitamin D3 actions in human breast cancer cells.
Plant Extracts of the Family Lauraceae: A Potential Resource for Chemopreventive Agents that Activate the Nuclear Factor-Erythroid 2-Related Factor 2/Antioxidant Response Element Pathway.
Plasma glucocorticogenic activity, race/ethnicity and alcohol intake among San Francisco Bay Area women.
Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression.
Posttranscriptional regulation of protein expression in human epithelial carcinoma cells by adenine-uridine-rich elements in the 3'-untranslated region of tumor necrosis factor-alpha messenger RNA.
Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system.
Proliferative and androgenic effects of indirubin derivatives in LNCaP human prostate cancer cells at sub-apoptotic concentrations.
Promoter characterization and genomic organization of the human breast cancer resistance protein (ATP-binding cassette transporter G2) gene.
Protein arginine methyltransferase 1 may be involved in pregnane x receptor-activated overexpression of multidrug resistance 1 gene during acquired multidrug resistant.
Rat model of metastatic breast cancer monitored by MRI at 3 tesla and bioluminescence imaging with histological correlation.
Regulating the tumor suppressor gene maspin in breast cancer cells: a potential mechanism for the anticancer properties of tamoxifen.
Regulation of heparanase gene expression by estrogen in breast cancer.
Regulation of the human vitamin D3 receptor promoter in breast cancer cells is mediated through Sp1 sites.
Relative potencies of individual polycyclic aromatic hydrocarbons to induce dioxinlike and estrogenic responses in three cell lines.
RNA binding protein PUM2 promotes the stemness of breast cancer cells via competitively binding to neuropilin-1 (NRP-1) mRNA with miR-376a.
Role of estrogen receptor ligand and estrogen response element sequence on interaction with chicken ovalbumin upstream promoter transcription factor (COUP-TF).
Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells.
Selection, Analysis and Improvement of Anti-Angiogenesis Compounds Identified by an Anti-HIF-1? Screening and Validation System.
Self-luminescent photodynamic therapy using breast cancer targeted proteins.
Sequence of the functional human keratin K14 promoter.
Sequential intravenous injection of anionic polymer and cationic lipoplex of siRNA could effectively deliver siRNA to the liver.
SERPINB5 Genetic Variants rs2289519 and rs2289521 are Significantly Associated with Gallbladder Cancer Risk.
Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6.
Smad4 as a transcription corepressor for estrogen receptor alpha.
SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ER?-positive breast cancer through regulation of BRCA1.
Specificity of action of a herpes virus VP16/tetracycline-dependent trans-activator in mammalian cell cultures.
Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome.
Structural basis for androgen receptor agonists and antagonists: Interaction of SPEED 98-listed chemicals and related compounds with the androgen receptor based on an in vitro reporter gene assay and 3D-QSAR.
Sunitinib inhibits lymphatic endothelial cell functions and lymph node metastasis in a breast cancer model through inhibition of vascular endothelial growth factor receptor 3.
Suppression of breast cancer metastasis and extension of survival by a new antiestrogen in a preclinical model driven by mutant estrogen receptors.
Tetraspanin CD9 is Regulated by miR-518f-5p and Functions in Breast Cell Migration and In Vivo Tumor Growth.
TGF?-induced c-Myb affects the expression of EMT-associated genes and promotes invasion of ER+ breast cancer cells.
The 'Gator' Mouse Suit for early bioluminescent metastatic breast cancer detection and nanomaterial signal enhancement during live animal imaging.
The challenge of determining the impact of FUT3 tumor-associated polymorphism rs2306969 (-6951 C> T) in invasive breast cancer cells.
The cis decoy against the estrogen response element suppresses breast cancer cells via target disrupting c-fos not mitogen-activated protein kinase activity.
The ERK/MAPK pathway regulates the activity of the human tissue factor pathway inhibitor-2 promoter.
The frequency of osteolytic bone metastasis is determined by conditions of the soil, not the number of seeds; evidence from in vivo models of breast and prostate cancer.
The genomic structure of the human SPEC1 gene reveals complex splicing and close promoter proximity to the AF1q translocation gene.
The kinetics of binding human prolactin, but not growth hormone, to the prolactin receptor vary over a physiologic pH range.
The long non-coding RNA SUMO1P3 facilitates breast cancer progression by negatively regulating miR-320a.
The modified firefly luciferase reporter gene (luc+) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells.
The neurogene BTG2TIS21/PC3 is transactivated by DeltaNp73alpha via p53 specifically in neuroblastoma cells.
The promotion of siRNA delivery to breast cancer overexpressing epidermal growth factor receptor through anti-EGFR antibody conjugation by immunoliposomes.
The significance of Runx2 mediating alcohol-induced Brf1 expression and RNA Pol III gene transcription.
Tissue factor pathway inhibitor-2 was repressed by CpG hypermethylation through inhibition of KLF6 binding in highly invasive breast cancer cells.
Toxicity of hydroxylated and quinoid PCB metabolites: inhibition of gap junctional intercellular communication and activation of aryl hydrocarbon and estrogen receptors in hepatic and mammary cells.
Transcriptional repression of p21 by EIF1AX promotes the proliferation of breast cancer cells.
Transcriptional repression of the cyclin-dependent kinase inhibitor p21WAF1/CIP1 gene mediated by cis elements present in the 3'-untranslated region.
Transcriptional targeting of adenoviral vector through the CXCR4 tumor-specific promoter.
Transcriptome-based identification of lovastatin as a breast cancer stem cell-targeting drug.
TRIP6 enhances stemness property of breast cancer cells through activation of Wnt/?-catenin.
Tumor angiogenesis therapy using targeted delivery of Paclitaxel to the vasculature of breast cancer metastases.
Tumor-suppressor microRNA-151-5p regulates the growth, migration and invasion of human breast cancer cells by inhibiting SCOS5.
UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization.
Use of Xenopus laevis as a model for investigating in vitro and in vivo endocrine disruption in amphibians.
UV filters with antagonistic action at androgen receptors in the MDA-kb2 cell transcriptional-activation assay.
Validated high-throughput screening of drug-like small molecules for inhibitors of ErbB2 transcription.
Validating the use of a luciferase labeled breast cancer cell line, MDA435LCC6, as a means to monitor tumor progression and to assess the therapeutic activity of an established anticancer drug, docetaxel (Dt) alone or in combination with the ILK inhibitor, QLT0267.
Variations in the NBN/NBS1 gene and the risk of breast cancer in non-BRCA1/2 French Canadian families with high risk of breast cancer.
Water quality assessment using the AREc32 reporter gene assay indicative of the oxidative stress response pathway.
Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells.
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.
ZEB1 directly inhibits GPX4 transcription contributing to ROS accumulation in breast cancer cells.
[Amplification of immune cells derived from human peripheral blood and cytotoxicity on MDA-MB-231 breast cancer cells in vitro].
[Constraction of triple negative breast cancer cell model containing EGFR promoter and luciferase reporter gene].
[Construction of Nude Mouse Model of Triple Negative Breast Cancer and Value of Thermal Tomography].
[Expression of XBP-1 in breast cancer cell lines and its role in ERalpha signaling]
[KLF3 regulates the movement, migration and invasion of breast cancer cells through STAT3].
[MiR-4443 promotes migration and invasion of breast cancer cells by inhibiting PEBP1 expression].
[N-ethyl- and [N,N'-diethyl-1,2-bis(2,6-difluoro-3-hydroxyphenyl)-ethylenediamine]dichloroplatinum(II): structure and cytotoxic/estrogenic activity in breast cancer cells.
Bronchitis
Expression of reporter genes from the defective RNA CD-61 of the coronavirus infectious bronchitis virus.
Burkitt Lymphoma
Characterization of the promoter region of human BCL-6 gene.
EBV?BART?6?3p and cellular microRNA?197 compromise the immune defense of host cells in EBV?positive Burkitt lymphoma.
Identification and characterization of an Epstein-Barr virus nuclear antigen 2-responsive cis element in the bidirectional promoter region of latent membrane protein and terminal protein 2 genes.
Isolation of the human interleukin 10 promoter. Characterization of the promoter activity in Burkitt's lymphoma cell lines.
Promoter sequences required for reactivation of Epstein-Barr virus from latency.
Carcinogenesis
A Cre/LoxP conditional luciferase reporter transgenic mouse for bioluminescence monitoring of tumorigenesis.
Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization.
Circular RNA circTUBGCP3 Is Up-Regulated and Promotes Cell Proliferation, Migration and Survivability via Sponge ?mir-30b in Osteosarcoma.
Circ_0000003 promotes the proliferation and metastasis of non-small cell lung cancer cells via miR-338-3p/insulin receptor substrate 2.
Down-regulation of miR-212 expression by DNA hypermethylation in human gastric cancer cells.
Effects of bioactive constituents in the Traditional Chinese Medicinal formula Si-Wu-Tang on Nrf2 signaling and neoplastic cellular transformation.
Elevated DDX21 regulates c-Jun activity and rRNA processing in human breast cancers.
Establishment of a novel method to evaluate peritoneal microdissemination and therapeutic effect using luciferase assay.
Hsa-mir-127 impairs survival of patients with glioma and promotes proliferation, migration and invasion of cancerous cells by modulating replication initiator 1.
IL-15 deficient tax mice reveal a role for IL-1? in tumor immunity.
Inhibition of Neoplastic Transformation and Chemically-Induced Skin Hyperplasia in Mice by Traditional Chinese Medicinal Formula Si-Wu-Tang.
LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer.
LncRNA DLX6-AS1 promotes the proliferation, invasion, and migration of non-small cell lung cancer cells by targeting the miR-27b-3p/GSPT1 axis.
LncRNA ZNFX1-AS1 targeting miR-193a-3p/SDC1 regulates cell proliferation, migration and invasion of bladder cancer cells.
Long non-coding RNA (LncRNA) MRPL23-AS1 promotes tumor progression and carcinogenesis in osteosarcoma by activating Wnt/?-catenin signaling via inhibiting microRNA miR-30b and upregulating myosin heavy chain 9 (MYH9).
Manganese superoxide dismutase is a p53-regulated gene that switches cancers between early and advanced stages.
Mediation of circ_RPPH1 on miR-146b-3p/E2F2 pathway to hinder the growth and metastasis of breast carcinoma cells.
Metformin inhibits tumorigenesis in HBV-induced hepatocellular carcinoma by suppressing HULC overexpression caused by HBX.
MicroRNA-365 promotes lung carcinogenesis by downregulating the USP33/SLIT2/ROBO1 signalling pathway.
microRNA-370 Promotes Cell Growth by Targeting WNK2 in Breast Cancer.
MicroRNA?16?5p regulates cell survival, cell cycle and apoptosis by targeting AKT3 in prostate cancer cells.
MicroRNA?224 is downregulated in mucinous cystic neoplasms of the pancreas and may regulate tumorigenesis by targeting Jagged1.
Midazolam inhibits proliferation and accelerates apoptosis of hepatocellular carcinoma cells by elevating microRNA-124-3p and suppressing PIM-1.
Minor allele of rs1057317 polymorphism in TLR4 is associated with increased risk of Helicobacter pylori -induced gastric cancer.
miR-130a acts as a potential diagnostic biomarker and promotes gastric cancer migration, invasion and proliferation by targeting RUNX3.
miR?122?5p suppresses the oncogenesis of PTC by inhibiting DUSP4 expression.
Restoration of microRNA-197 expression suppresses oncogenicity in fibrosarcoma through negative regulation of RAN.
SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells.
Structure-activity relationship of salicylic acid derivatives on inhibition of TNF-? dependent NF?B activity: Implication on anti-inflammatory effect of N-(5-chlorosalicyloyl)phenethylamine against experimental colitis.
The application of a murine bone bioreactor as a model of tumor: bone interaction.
The Long Noncoding RNA, Growth Arrest-Specific 5, Suppresses Gastric Cancer by Downregulating miR-21 Expression.
The stress-activated protein kinase pathway and the expression of stanniocalcin-1 are regulated by miR-146b-5p in papillary thyroid carcinogenesis.
Upregulated circ RNA hsa_circ_0000337 promotes cell proliferation, migration, and invasion of esophageal squamous cell carcinoma.
Wild-type IDH2 contributes to Epstein-Barr virus-dependent metabolic alterations and tumorigenesis.
Carcinoma
A cationic cytofectin with long spacer mediates favourable transfection in transformed human epithelial cells.
A comparison of in vitro and in vivo EDSTAC test battery results for detecting antiandrogenic activity.
A functional haplotype of NFKB1 influence susceptibility to oral cancer: a population-based and in vitro study.
A mixture of persistent organic pollutants relevant for human exposure inhibits the transactivation activity of the aryl hydrocarbon receptor in vitro.
A new luciferase reporter gene assay for the detection of androgenic and antiandrogenic effects based on a human prostate specific antigen promoter and PC3/AR human prostate cancer cells.
A novel bioluminescent tumor model of human renal cancer cell lines: an in vitro and in vivo characterization.
Acquisition of doxorubicin resistance in ovarian carcinoma cells accompanies activation of the NRF2 pathway.
Activation of Sp1-mediated vascular permeability factor/vascular endothelial growth factor transcription requires specific interaction with protein kinase C zeta.
Activity of the adenoviral E1A deletion mutant dl922-947 in ovarian cancer: comparison with E1A wild-type viruses, bioluminescence monitoring, and intraperitoneal delivery in icodextrin.
An anti-inflammatory mechanism of taurine conjugated 5-aminosalicylic acid against experimental colitis: taurine chloramine potentiates inhibitory effect of 5-aminosalicylic acid on IL-1beta-mediated NFkappaB activation.
Animal models of bone metastasis.
Anti-inflammatory and anticancer activities of extracts and compounds from the mushroom Inonotus obliquus.
Antiandrogenic activities of diesel exhaust particle extracts in PC3/AR human prostate carcinoma cells.
Antitumor potential of SLPI promoter controlled recombinant caspase-3 expression in laryngeal carcinoma.
Application of biodegradable dendrigraft poly-l-lysine to a small interfering RNA delivery system.
Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients.
Augmentation of melanoma-specific gene expression using a tandem melanocyte-specific enhancer results in increased cytotoxicity of the purine nucleoside phosphorylase gene in melanoma.
Baculovirus P35 interacts with a subunit of human RNA polymerase II and can enhance promoter activity in human cells.
BAG2 mediates coelomocyte apoptosis in Vibrio splendidus challenged sea cucumber Apostichopus japonicus.
Binary gene vectors based on hyperbranched poly(l-lactide-co-polyglycerol) and polyethylenimine for prolonged transgene expression via co-assembly with DNA into fiber core-shell triplexes.
Biological activity profiles of 1alpha,25-dihydroxyvitamin D2, D3, D4, D7, and 24-epi-1alpha,25-dihydroxyvitamin D2.
Biotransformation of 20(R)-panaxadiol by the fungus Rhizopus chinensis.
Calcium enhanced delivery of tetraarginine-PEG-lipid-coated DNA/protamine complexes.
Cationic lipids with increased DNA binding affinity for nonviral gene transfer in dividing and nondividing cells.
Cellular internalization and gene silencing of siRNA polyplexes by cytocleavable cationic polyrotaxanes with tailored rigid backbones.
Cepharanthin-enhanced radiosensitivity through the inhibition of radiation-induced nuclear factor-kappaB activity in human oral squamous cell carcinoma cells.
Characterization of a functional promoter polymorphism of the human tryptophan hydroxylase 2 gene in serotonergic raphe neurons.
Characterization of the basal promoter element of the human type 5 17beta-hydroxysteroid dehydrogenase gene.
Characterization of the human somatostatin receptor type 4 promoter.
Characterization of the promoter for the mouse alpha 3 integrin gene.
CircAMOTL1 Promotes Tumorigenesis Through miR-526b/SIK2 Axis in Cervical Cancer.
Cisplatin and taxol activate different signal pathways regulating cellular injury-induced expression of GADD153.
Cloning and characterization of the porcine IL-10 promoter.
Cloning and molecular dissection of the 8.8 kb pig uroplakin II promoter using transgenic mice and RT4 cells.
Comparison of implantation sites for the development of peritoneal metastasis in a colorectal cancer mouse model using non-invasive bioluminescence imaging.
Comparison of transfection efficiency of nonviral gene transfer reagents.
Construction and characterization of a reporter gene cell line for assessment of human glucocorticoid receptor activation.
Cryoimmunotherapy with local co-administration of ex vivo generated dendritic cells and CpG-ODN immune adjuvant, elicits a specific antitumor immunity.
Dipeptidyl peptidase 4 serum activity and concentration are increased in women with polycystic ovary syndrome.
DNA polymerase ? promoter mutations and transcriptional activity in esophageal squamous cell carcinoma.
E2F-Rb complexes assemble and inhibit cdc25A transcription in cervical carcinoma cells following repression of human papillomavirus oncogene expression.
Efficient gene delivery using anionic liposome-complexed polyplexes (LPDII).
Enhanced in vitro and in vivo cationic lipid-mediated gene delivery with a fluorinated glycerophosphoethanolamine helper lipid.
ERK5?regulated RERG expression promotes cancer progression in prostatic carcinoma.
Establishment and characterization of transplantable, luminescence labeled rat renal cell carcinoma cell lines.
Establishment of a bioluminescent Renca cell line for renal carcinoma research.
Eudesmane-Type Sesquiterpene Lactones Inhibit Nuclear Translocation of the Nuclear Factor ?B Subunit RelB in Response to a Lymphotoxin ? Stimulation.
Evaluation of estrogenic activities of pesticides using an in vitro reporter gene assay.
Exploring the MIR143-UPAR Axis for the Inhibition of Human Prostate Cancer Cells In Vitro and In Vivo.
Expression of tdTomato and luciferase in a murine lung cancer alters the growth and immune microenvironment of the tumor.
Factors limiting adenovirus-mediated gene transfer into human lung and pancreatic cancer cell lines.
Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells.
Functional analysis of TCF7L2 genetic variants associated with type 2 diabetes.
Genetic modification of cancer cells using non-viral, episomal S/MAR vectors for in vivo tumour modelling.
Genomic organization and promoter analysis of mouse follistatin-related gene (FLRG).
Genomic organization and promoter characterization of the rat cyclin B1 gene.
Genomic structure and transcriptional regulation of the human somatostatin receptor type 2.
Genotyping and functional analysis of a polymorphic (CCTTT)(n) repeat of NOS2A in diabetic retinopathy.
Host mediated anti-tumor effect of oncolytic Newcastle disease virus after locoregional application.
Hypoxia imaging predicts success of hypoxia-induced cytosine deaminase/5-fluorocytosine gene therapy in a murine lung tumor model.
Hypoxia-induced activation of p38 mitogen-activated protein kinase and phosphatidylinositol 3'-kinase signaling pathways contributes to expression of interleukin 8 in human ovarian carcinoma cells.
Hypoxia-induced cytosine deaminase gene expression for cancer therapy.
Identification and characterization of the Oct4 extended transcriptional regulatory region in Guanzhong dairy goat.
Identification and Characterization of the OCT4 Upstream Regulatory Region in Sus scrofa.
Identification of an upstream pituitary-active promoter of human somatostatin receptor subtype 5.
Identification of miR-200a-5p targeting the peptide transporter TAP1 and its association with the clinical outcome of melanoma patients.
Identification of MYCBP as a beta-catenin/LEF-1 target using DNA microarray analysis.
Identification of Small Molecule Activators of BMP Signaling.
Identification of the human HEX1/hExo1 gene promoter and characterization of elements responsible for promoter activity.
IgH intronic enhancer element HE2 (mu B) functions as a cis-activator in choroid plexus cells at the cellular level as well as in transgenic mice.
In vitro biological activities of a series of 2 beta-substituted analogues of 1 alpha,25-dihydroxyvitamin D3.
In vivo imaging models of bone and brain metastases and pleural carcinomatosis with a novel human EML4-ALK lung cancer cell line.
In vivo imaging of retinoic acid receptor beta2 transcriptional activation by the histone deacetylase inhibitor MS-275 in retinoid-resistant prostate cancer cells.
Incorporation of reversibly cross-linked polyplexes into LPDII vectors for gene delivery.
Inhibition of cyclooxygenase-1 and -2 expression by targeting the endothelin a receptor in human ovarian carcinoma cells.
Inhibition of Prostate Cancer Bone Metastasis by Synthetic TF Antigen Mimic/Galectin-3 Inhibitor Lactulose-l-Leucine.
Inhibition of tumor growth by DT-A expressed under the control of IGF2 P3 and P4 promoter sequences.
Interleukin-12 gene transfer results in CD8-dependent regression of murine CT26 liver tumors.
Intratracheal administration of a nanoparticle-based therapy with the angiotensin II type 2 receptor gene attenuates lung cancer growth.
Investigation of Targeting Relationship between Micro-Rna-22 and Vegfr3 in Lung Squamous Cell Carcinoma.
LncRNA LOXL1-AS1 facilitates the tumorigenesis and stemness of gastric carcinoma via regulation of miR-708-5p/USF1 pathway.
LncRNA PVT1 accelerates malignant phenotypes of bladder cancer cells by modulating miR-194-5p/BCLAF1 axis as a ceRNA.
Long non-coding RNA TMPO-AS1 serves as a tumor promoter in pancreatic carcinoma by regulating miR-383-5p/SOX11.
Luciferase activity as a marker of tumor burden and as an indicator of tumor response to antineoplastic therapy in vivo.
MDM2 negatively regulates the human telomerase RNA gene promoter.
Metastatic burden in nude mice organs measured using prostate tumor PC-3 cells expressing the luciferase gene as a quantifiable tumor cell marker.
MicroRNA-125a-5p modulates human cervical carcinoma proliferation and migration by targeting ABL2.
microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN.
MicroRNA?19a mediates gastric carcinoma cell proliferation through the activation of nuclear factor??B.
MicroRNA?98/PTEN/AKT pathway inhibits cell proliferation and malignant progression of hypopharyngeal carcinoma by MTDH.
miR-218 suppressed the growth of lung carcinoma by reducing MEF2D expression.
miR-222 promotes invasion and migration of ovarian carcinoma by targeting PTEN.
Molecular cloning of a murine type III sodium-dependent phosphate cotransporter (Pit-2) gene promoter.
Murine neuronal progenitor cells are preferentially recruited to tumor vasculature via alpha4-integrin and SDF-1alpha-dependent mechanisms.
Naturally Occurring Variations Modulate the Activity of the HPV33 Early Promoter and its Affinity for the E2 Transcription Factor.
Nifedipine inhibits activation of transcription factor NF-kappaB.
Non-invasive monitoring of hypoxia-inducible factor activation by optical imaging during antiangiogenic treatment in a xenograft model of ovarian carcinoma.
Nonviral gene delivery to human ovarian cancer cells using arginine-grafted PAMAM dendrimer.
Novel ring A stereoisomers of 2-methyl-1alpha,25-dihydroxyvitamin D(3) and 2-methyl-20-epi-1alpha,25-dihydroxyvitamin D(3): transactivation of target genes and modulation of differentiation in human promyelocytic leukemia (HL-60) cells.
Novel siRNA delivery system using a ternary polymer complex with strong silencing effect and no cytotoxicity.
Organic dust activates NF-kappaB in lung epithelial cells.
Overexpression of EGR-1 modulates the activity of NF-?B and AP-1 in prostate carcinoma PC-3 and LNCaP cell lines.
Phenethyl isothiocyanate suppresses cancer stem cell properties in vitro and in a xenograft model.
Phospholipid Phosphatase 4 promotes proliferation and tumorigenesis, and activates Ca(2+)-permeable Cationic Channel in lung carcinoma cells.
Physiologic and molecular characterization of a novel murine model of metastatic head and neck cancer cachexia.
PO-16 - ASK1 regulates tumor lung metastasis and platelet functions.
Positive and negative regulatory regions in promoters of human glutathione transferase alpha genes.
Pre-B-cell leukemia transcription factor 1 regulates expression of valosin-containing protein, a gene involved in cancer growth.
Promoter activity of SARS coronavirus 5' UTR sequence in eukaryotic cells.
Promoter characterization of the novel human matrix metalloproteinase-26 gene: regulation by the T-cell factor-4 implies specific expression of the gene in cancer cells of epithelial origin.
Prompt assessment of WST11-VTP outcome using luciferase transfected tumors enables second treatment and increase in overall therapeutic rate.
Protein synthesis inhibitors, in synergy with 5-azacytidine, restore sodium/iodide symporter gene expression in human thyroid adenoma cell line, KAK-1, suggesting trans-active transcriptional repressor.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Reciprocal transactivation of Merkel cell polyomavirus and high-risk human papillomavirus promoter activities and increased expression of their oncoproteins.
Recombinant cell bioassays for endocrine disruptors: development of a stably transfected human ovarian cell line for the detection of estrogenic and anti-estrogenic chemicals.
Regulation of CYP1A1 gene expression by the antioxidant tert-butylhydroquinone.
Repression of the rat steroidogenic acute regulatory (StAR) protein gene by PGF2alpha is modulated by the negative transcription factor DAX-1.
Safe and effective delivery of small interfering RNA with polymer- and liposomes-based complexes.
Selective Imaging of Malignant Ascites in a Mouse Model of Peritoneal Metastasis Using in Vivo Dynamic Nuclear Polarization-Magnetic Resonance Imaging.
Serum decreases the size of Metafectene-and Genejammer-DNA complexes but does not affect significantly their transfection activity in SCCVII murine squamous cell carcinoma cells.
SSRP1 functions as a co-activator of the transcriptional activator p63.
Structure and expression pattern of Oct4 gene are conserved in vole Microtus rossiaemeridionalis.
Structure and regulation of the human growth hormone-releasing hormone receptor gene.
Structure of the 5' sequences of the human gamma-glutamyltransferase gene.
Systemic dissemination of viral vectors during intratumoral injection.
Targeted gene therapy and in vivo bioluminescent imaging for monitoring postsurgical recurrence and metastasis in mouse models of liver cancer.
Targeted therapy of spontaneous murine pancreatic tumors by polymeric micelles prolongs survival and prevents peritoneal metastasis.
The 3' UTR of human MnSOD mRNA hybridizes to a small cytoplasmic RNA and inhibits gene expression.
The cluster of miR-143 and miR-145 affects the risk for esophageal squamous cell carcinoma through co-regulating fascin homolog 1.
The cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathway.
The ERK/MAPK pathway regulates the activity of the human tissue factor pathway inhibitor-2 promoter.
The Expression of miR-375 Is Associated with Carcinogenesis in Three Subtypes of Lung Cancer.
The expression of the H19 gene and its function in human bladder carcinoma cell lines.
The mitochondrial apoptosis-inducing factor plays a role in E2F-1-induced apoptosis in human colon cancer cells.
The putative tumor suppressor, miR-199a, regulated by Snail, modulates clear cell renal cell carcinoma aggressiveness by repressing ROCK1.
The restricted expression pattern of the Hodgkin's lymphoma-associated cytokine receptor CD30 is regulated by a minimal promoter.
The role of Lutheran/basal cell adhesion molecule in human bladder carcinogenesis.
The use of a human papillomavirus 18 promoter for tissue-specific expression in cervical carcinoma cells.
The Usefulness of Bone Biomarkers for Monitoring Treatment Disease: A Comparative Study in Osteolytic and Osteosclerotic Bone Metastasis Models.
Thyroxine promotes lung cancer growth in an orthotopic mouse model.
Trans complementation of an E1A-deleted adenovirus with codelivered E1A sequences to make recombinant adenoviral producer cells.
Transcriptional activation of the human manganese superoxide dismutase gene mediated by tetradecanoylphorbol acetate.
Transcriptional regulation of 17beta-hydroxysteroid dehydrogenase type 12 by SREBP-1.
Transcriptional regulation of the rat steroidogenic acute regulatory protein gene by steroidogenic factor 1.
Truncating mutations of PPM1D are found in blood DNA samples of lung cancer patients.
Upregulation of bax Gene Expression Promotes Paclitaxel-induced Apoptosis in Esophageal Carcinoma Cells.
Upregulation of microRNA-204 inhibits cell proliferation, migration and invasion in human renal cell carcinoma cells by downregulating SOX4.
Use of H19 Gene Regulatory Sequences in DNA-Based Therapy for Pancreatic Cancer.
Use of in vivo bioluminescence imaging to predict hepatic tumor burden in mice.
Valproic acid enhances Oct4 promoter activity in myogenic cells.
Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway.
Winged helix hepatocyte nuclear factor 3 and POU-domain protein brn-2/N-oct-3 bind overlapping sites on the neuronal promoter of human aromatic L-amino acid decarboxylase gene.
Wnt/Beta-Catenin Signal Inhibitor HC-1 Sensitizes Oral Squamous Cell Carcinoma Cells to 5-Fluorouracil through Reduction of CD44-Positive Population.
[Effect of 14-3-3sigma on transcriptional activity of p73 gene]
[Effect of inhibitor RNA on intracellular inhibition of viral gene expression in 5'-noncoding region of hepatitis C virus]
[Expression of fused luxAB gene of bacterial luciferase in liver carcinoma cells]
[Inflammatory factors promote oral squamous cell carcinoma cells metastasis, via nuclear factor kappa B signal pathway in vitro]
[Proliferation of MicroRNA-365 and E74-like Factor 4 in Cervical Cancer Cells and Its Clinical Significance].
Carcinoma, Embryonal
Altered regulation of platelet-derived growth factor receptor-alpha gene-transcription in vitro by spina bifida-associated mutant Pax1 proteins.
DNA methylation represses the murine alpha 1(I) collagen promoter by an indirect mechanism.
Genome-wide gain-of-function screen identifies novel regulators of pluripotency.
Genomic structure and promoter activity of the mouse polysialic acid synthase (mST8Sia IV/PST) gene.
Molecular cloning, genetic mapping, and developmental expression of bovine POU5F1.
Regulation of human Cripto-1 gene expression by TGF-beta1 and BMP-4 in embryonal and colon cancer cells.
Regulation of the rat oxytocin gene by estradiol.
Vasopressin gene expression is stimulated by cyclic AMP in homologous and heterologous expression systems.
Carcinoma, Hepatocellular
12(R)-Hydroxy-5(Z),8(Z),10(E),14(Z)-eicosatetraenoic acid [12(R)-HETE], an arachidonic acid derivative, is an activator of the aryl hydrocarbon receptor.
17beta-Estradiol inhibits cytokine induction of the human E-selectin promoter.
6-Hydroxy-3-O-methyl-kaempferol 6-O-glucopyranoside potentiates the anti-proliferative effect of interferon ?/? by promoting activation of the JAK/STAT signaling by inhibiting SOCS3 in hepatocellular carcinoma cells.
A 2-Benzylmalonate Derivative as STAT3 Inhibitor Suppresses Tumor Growth in Hepatocellular Carcinoma by Upregulating ?-TrCP E3 Ubiquitin Ligase.
A Biomimetic, One-Step Transformation of Simple Indolic Compounds to Malassezia-Related Alkaloids with High AhR Potency and Efficacy.
A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system.
A composition of medicinal plants with an enhanced ability to suppress microsomal lipid peroxidation and a protective activity against carbon tetrachloride-induced hepatotoxicity.
A Fibroblast Growth Factor 21-Pregnane X Receptor Pathway Downregulates Hepatic CYP3A4 in Nonalcoholic Fatty Liver Disease.
A hepatocyte nuclear factor-3 site in the fibrinogen beta promoter is important for interleukin 6-induced expression, and its activity is influenced by the adjacent -148C/T polymorphism.
A liver enhancer in the fibrinogen gene cluster.
A mixture of persistent organic pollutants relevant for human exposure inhibits the transactivation activity of the aryl hydrocarbon receptor in vitro.
A mutant of hepatitis B virus X protein (HBx Delta 127) enhances hepatoma cell migration via osteopontin involving 5-lipoxygenase.
A new bioluminescent imaging technology for studying oxidative stress in the testis and its impacts on fertility.
A novel polymorphism in the promoter region of human UGT1A9 gene (UGT1A9*22) and its effects on the transcriptional activity.
A novel regulatory element between the human FGA and FGG genes.
A pharmacogenomics study of the human estrogen glucuronosyltransferase UGT1A3.
A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides.
A stable fish reporter cell line to study estrogen receptor transactivation by environmental (xeno)estrogens.
A suppressive role of ionizing radiation-responsive miR-29c in the development of liver carcinoma via targeting WIP1.
Activated macrophages induce hepcidin expression in HuH7 hepatoma cells.
Activation of the aryl hydrocarbon receptor by berberine in HepG2 and H4IIE cells: Biphasic effect on CYP1A1.
Alpha,beta-unsaturated aldehydes increase glutathione S-transferase mRNA and protein: correlation with activation of the antioxidant response element.
Alternative 5' Untranslated Regions Are Involved in Expression Regulation of Human Heme Oxygenase-1.
Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding.
Androgen receptor antagonism by the organophosphate insecticide fenitrothion.
Applicability of the CALUX bioassay for screening of dioxin levels in human milk samples.
Aryl hydrocarbon receptor activation and cytochrome P450 1A induction by the mitogen-activated protein kinase inhibitor U0126 in hepatocytes.
Aryl hydrocarbon receptor ligand activity of polycyclic aromatic ketones and polycyclic aromatic quinones.
Association between indel polymorphism in the promoter region of lncRNA GAS5 and the risk of hepatocellular carcinoma.
Autonomous parvovirus transduction of a gene under control of tissue-specific or inducible promoters.
Binding of STAT5a and STAT5b to a single element resembling a gamma-interferon-activated sequence mediates the growth hormone induction of the mouse acid-labile subunit promoter in liver cells.
Bioanalytical screening of low levels of dioxins and dioxin-like PCBs in pig meat (pork) for checking compliance with EU maximum and action levels using highly sensitive "third generation" recombinant H4L7.5c2 rat hepatoma cells.
Bioluminescent imaging of hepatocellular carcinoma in live mice.
Ca2+ administration stimulates the binding of AP-1 factor to the 5'-flanking region of the rat gene for the Ca2+-binding protein regucalcin.
Characteristics and application of established luciferase hepatoma cell line that responds to dioxin-like chemicals.
Characterization and regulatory effect of gamma-glutamyltransferase messenger RNA untranslated regions in human leukemia.
Characterization of cis-elements mediating the stimulation of glucose-6-phosphate transporter promoter activity by glucocorticoids.
Characterization of rat liver-specific methionine adenosyltransferase gene promoter. Role of distal upstream cis-acting elements in the regulation of the transcriptional activity.
Characterization of the 5'-flanking region of the rat TIS11 gene.
Chemical-activated luciferase gene expression (CALUX): a novel in vitro bioassay for Ah receptor active compounds in sediments and pore water.
Chicken leptin receptor is functional in activating JAK-STATpathway in vitro.
Cloning and characterization of a functional promoter of the rat pp120 gene, encoding a substrate of the insulin receptor tyrosine kinase.
Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication.
Cloning and characterization of the human factor XI gene promoter: transcription factor hepatocyte nuclear factor 4alpha (HNF-4alpha ) is required for hepatocyte-specific expression of factor XI.
Cloning and characterization of the rat apobec-1 gene: a comparative analysis of gene structure and promoter usage in rat and mouse.
Cloning and functional characterization of the ovine malic enzyme promoter.
Cloning and gene structure of rat phosphatidylcholine transfer protein, Pctp.
Cloning and sequencing of the 5' region of the human glucose-6-phosphatase gene: transcriptional regulation by cAMP, insulin and glucocorticoids in H4IIE hepatoma cells.
Combinatorial interactions of p53, activating protein-2, and YB-1 with a single enhancer element regulate gelatinase A expression in neoplastic cells.
Comparison of Ah receptor-mediated luciferase and ethoxyresorufin-O-deethylase induction in H4IIE cells: implications for their use as bioanalytical tools for the detection of polyhalogenated aromatic hydrocarbons.
Comparison of transfection efficiency of nonviral gene transfer reagents.
Daily timed meals dissociate circadian rhythms in hepatoma and healthy host liver.
Determinations of dioxinlike activity in selected mollusks from the coast of the Bohai Sea, China, using the H4IIE-luc bioassay.
Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line.
Developmental effects of dietary phytoestrogens in Sprague-Dawley rats and interactions of genistein and daidzein with rat estrogen receptors alpha and beta in vitro.
Dexamethasone induction of murine CYP2B genes requires the glucocorticoid receptor.
Dibenzoylmethane activates Nrf2-dependent detoxification pathway and inhibits benzo(a)pyrene induced DNA adducts in lungs.
Dietary polyphenols identified as intracellular protein kinase A inhibitors.
Different activities of type I interferons on hepatitis B virus core promoter regulated transcription.
Different structural requirements of the ligand binding domain of the aryl hydrocarbon receptor for high- and low-affinity ligand binding and receptor activation.
Differential expression of the transfected liver-specific alpha 1-inhibitor III gene in normal hepatocytes and hepatoma cells in culture.
Differential glucocorticoid enhancement of the cytokine-driven transcriptional activation of the human acute phase serum amyloid A genes, SAA1 and SAA2.
Differential interaction of the methoxychlor metabolite 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane with estrogen receptors alpha and beta.
Differential promoter usage in prolactin receptor gene expression: hepatocyte nuclear factor 4 binds to and activates the promoter preferentially active in the liver.
Diluted mainstream cigarette smoke condensates activate estrogen receptor and aryl hydrocarbon receptor-mediated gene transcription.
Dioxin induces transcription of fos and jun genes by Ah receptor-dependent and -independent pathways.
Dioxin-like activity of brominated dioxins as individual compounds or mixtures in in vitro reporter gene assays with rat and mouse hepatoma cell lines.
Effect of pitavastatin on transactivation of human serum paraoxonase 1 gene.
Effective infection, apoptotic cell killing and gene transfer of human hepatoma cells but not primary hepatocytes by parvovirus H1 and derived vectors.
Effects of dinuclear copper(II) complexes with 6-(benzylamino)purine derivatives on AhR and PXR dependent expression of cytochromes P450 CYP1A2 and CYP3A4 genes in primary cultures of human hepatocytes.
Effects of Maerua subcordata (Gilg) DeWolf on electrophile-responsive element (EpRE)-mediated gene expression in vitro.
Effects of polybrominated diphenyl ethers on basal and TCDD-induced ethoxyresorufin activity and cytochrome P450-1A1 expression in MCF-7, HepG2, and H4IIE cells.
Efficiency of mammalian selenocysteine incorporation.
Efficient hepatic delivery and protein expression enabled by optimized mRNA and ionizable lipid nanoparticle.
Elevated expression of coactivator-associated arginine methyltransferase 1 is associated with early hepatocarcinogenesis.
Enhanced gene transfer into HuH-7 cells and primary rat hepatocytes using targeted liposomes and polyethylenimine.
Eradication of hepatocellular carcinoma xenografts by radiolabelled, lipiodol-inducible gene therapy.
Establishment of a stable aryl hydrocarbon receptor-responsive HepG2 cell line.
Estrogen stimulates SREBP2 expression in hepatic cell lines via an estrogen response element in the SREBP2 promoter.
Evidence for anti-inflammatory activity of statins and PPARalpha activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro.
Exosomal miR-106b-5p derived from melanoma cell promotes primary melanocytes epithelial-mesenchymal transition through targeting EphA4.
Exploration of anti-cancer effects and mechanisms of Zuo-Jin-Wan and its alkaloid components in vitro and in orthotopic HepG2 xenograft immunocompetent mice.
Flavone antagonists bind competitively with 2,3,7, 8-tetrachlorodibenzo-p-dioxin (TCDD) to the aryl hydrocarbon receptor but inhibit nuclear uptake and transformation.
Functional activity of hepatocyte nuclear factor-1 is specifically decreased in amino acid-limited hepatoma cells.
Functional analysis of glucocorticoid and insulin response sequences in the rat insulin-like growth factor-binding protein-1 promoter.
Functional characterization of genetic polymorphisms identified in the promoter region of the xanthine oxidase gene.
Functional characterization of the bovine conglutinin promoter: presence of a novel element for transcriptional regulation of a C-type mammalian lectin containing a collagen-like domain.
Gene organization of human protein C inhibitor, a member of SERPIN family proteins encoded in five exons.
Gene transfer mediated by alpha2-macroglobulin.
Generation of stable ARE- driven reporter system for monitoring oxidative stress.
Genetic modification of cancer cells using non-viral, episomal S/MAR vectors for in vivo tumour modelling.
Genomic organization and promoter characterization of the rat cyclin B1 gene.
Ginsenoside Rg1 down-regulates glucocorticoid receptor and displays synergistic effects with cAMP.
Glucose-modulated transgene expression via recombinant adeno-associated virus.
HBV Upregulates CtBP2 Expression via the X Gene.
HBX protein promotes LASP-1 expression through activation of c-Jun in human hepatoma cells.
Hepatitis B virus X protein upregulates expression of calpain small subunit 1 via nuclear factor-kappaB/p65 in hepatoma cells.
Hepatitis C virus core protein interacts with cellular putative RNA helicase.
Hepatitis C virus IRES-dependent translation is insensitive to an eIF2alpha-independent mechanism of inhibition by interferon in hepatocyte cell lines.
Hepatitis C virus NS2 protein activates cellular cyclic AMP-dependent pathways.
Hepatitis C virus NS5A mediated STAT3 activation requires co-operation of Jak1 kinase.
hsa_circ_0006916 promotes hepatocellular carcinoma progression by activating the miR-337-3p/STAT3 axis.
Human ethanol-inducible P450IIE1: complete gene sequence, promoter characterization, chromosome mapping, and cDNA-directed expression.
Identification of a cAMP response element within the glucose- 6-phosphatase hydrolytic subunit gene promoter which is involved in the transcriptional regulation by cAMP and glucocorticoids in H4IIE hepatoma cells.
Identification of a glucocorticoid response element in the human gamma chain fibrinogen promoter.
Identification of a liver-specific promoter for the ovine growth hormone receptor.
Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase.
Identification of a single nucleotide polymorphism in the TATA box of the CYP2A6 gene: impairment of its promoter activity.
Identification of Functional Transcriptional Binding Sites within Chicken Abcg2 Gene Promoter and Screening Its Regulators.
Identification of potential aryl hydrocarbon receptor antagonists in green tea.
Identification of promoter response elements that mediate propionate induction of bovine cytosolic phosphoenolpyruvate carboxykinase (PCK1) gene transcription.
Identification of proximal and distal regulatory elements of the rat connexin32 gene.
Identification of small molecule activators of the janus kinase/signal transducer and activator of transcription pathway using a cell-based screen.
Identification of Small Molecule Modulators of MicroRNA by Library Screening.
IL-17A Secreted from Lymphatic Endothelial Cells Promotes Tumorigenesis by Up-regulation of PD-L1 in Hepatoma Stem Cells.
In vitro antiestrogenic effects of aryl methyl sulfone metabolites of polychlorinated biphenyls and 2,2-bis(4-chlorophenyl)-1,1-dichloroethene on 17beta-estradiol-induced gene expression in several bioassay systems.
In vitro evaluation of an enhanced human serum amyloid A (SAA2) promoter-regulated soluble TNF receptor fusion protein for anti-inflammatory gene therapy.
Induction of an estrogen-responsive reporter gene in rainbow trout hepatoma cells (RTH 149) at 11 or 18 degrees C.
Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women's Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A.
Inefficiency of expression of luciferase reporter from transfected murine leukaemia proviral DNA may be partially overcome by providing a strong polyadenylation signal.
Influence of aromatic hydrocarbon receptor-mediated events on the genotoxicity of cigarette smoke condensate.
Inhibition of the cancer stem cells-like properties by arsenic trioxide, involved in the attenuation of endogenous transforming growth factor beta signal.
Inhibitory effect of tumor suppressor p33(ING1b) and its synergy with p53 gene in hepatocellular carcinoma.
Interaction of diuron and related substituted phenylureas with the Ah receptor pathway.
Interaction of methoxychlor and related compounds with estrogen receptor alpha and beta, and androgen receptor: structure-activity studies.
Interaction of organophosphate pesticides and related compounds with the androgen receptor.
Interactions of polybrominated diphenyl ethers with the aryl hydrocarbon receptor pathway.
Interferon-alpha enhances TRAIL-mediated apoptosis by up-regulating caspase-8 transcription in human hepatoma cells.
Interferon-alpha mediates suppression of C-reactive protein: explanation for muted C-reactive protein response in lupus flares?
Involvement of pregnane x receptor in the regulation of CYP2B6 gene expression by oltipraz in human hepatocytes.
In vitro differential responses of rat and human aryl hydrocarbon receptor to two distinct ligands and to different polyphenols.
Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3.
Ligand substitution of receptor targeted DNA complexes affects gene transfer into hepatoma cells.
Liver cell-specific transcriptional regulation of connexin32.
Long non-coding RNA TPTEP1 inhibits hepatocellular carcinoma progression by suppressing STAT3 phosphorylation.
Luciferase reporter assay for small-molecule inhibitors of MIR92b-3p function: Screening cyanopeptolins produced by Nostoc from the Baltic Sea.
Mechanism of AMPK suppression of LXR-dependent Srebp-1c transcription.
Membrane-initiated steroid signaling (MISS): genomic steroid action starts at the plasma membrane.
Metal interference on luciferase activity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in bioassays of recombinant mouse hepatoma cells.
MicroRNA-138 inhibits cell proliferation in hepatocellular carcinoma by targeting Sirt1.
MicroRNA-34c-3p promotes cell proliferation and invasion in hepatocellular carcinoma by regulation of NCKAP1 expression.
MicroRNA-639 is Down-Regulated in Hepatocellular Carcinoma Tumor Tissue and Inhibits Proliferation and Migration of Human Hepatocellular Carcinoma Cells Through the KAT7/Wnt/?-Catenin Pathway.
miR-199b exerts tumor suppressive functions in hepatocellular carcinoma by directly targeting JAG1.
miR-224 is Critical for Celastrol-Induced Inhibition of Migration and Invasion of Hepatocellular Carcinoma Cells.
MiR-887 Promotes the Progression of Hepatocellular Carcinoma via Targeting VHL.
Modulation of receptor phosphorylation contributes to activation of peroxisome proliferator activated receptor alpha by dehydroepiandrosterone and other peroxisome proliferators.
Molecular cloning and functional analysis of the promoter of the human squalene synthase gene.
Molecular cloning of the human AH receptor gene promoter.
Molecular mechanism of Mitomycin C-dependent caspase-8 regulation: implications for apoptosis and synergism with interferon-alpha signalling.
Molecular pathogenesis of Gilbert's syndrome: decreased TATA-binding protein binding affinity of UGT1A1 gene promoter.
Mouse cytosolic class 3 aldehyde dehydrogenase (Aldh3a1): gene structure and regulation of constitutive and dioxin-inducible expression.
Multidrug resistance gene expression in rodents and rodent hepatocytes treated with mitoxantrone.
NADPH Oxidase-Dependent Mechanism Explains How Arsenic and Other Oxidants Can Activate Aryl Hydrocarbon Receptor Signaling.
Nanoparticles of compacted DNA transfect postmitotic cells.
NF-kappaB plays a key role in hypoxia-inducible factor-1-regulated erythropoietin gene expression.
NF-Y and Sp1 are involved in transcriptional regulation of rat SND p102 gene.
Novel stably transfected gene reporter human hepatoma cell line for assessment of aryl hydrocarbon receptor transcriptional activity: construction and characterization.
Nuclear transcription factor Oct-1 binds to the 5'-upstream region of CYP1A1 and negatively regulates its expression.
Phase 2 enzyme induction by the major metabolite of oltipraz.
Phenolic Diterpenes from Rosemary Suppress cAMP Responsiveness of Gluconeogenic Gene Promoters.
Phorbol ester-induced activation of mitogen-activated protein kinase/extracellular-signal-regulated kinase kinase and extracellular-signal-regulated protein kinase decreases glucose-6-phosphatase gene expression.
Physical and functional interaction of Acyl-CoA-binding protein with hepatocyte nuclear factor-4 alpha.
Polymorphism of the human alcohol dehydrogenase 4 (ADH4) promoter affects gene expression.
Posttranscriptional regulation of acute phase serum amyloid A2 expression by the 5'- and 3'-untranslated regions of its mRNA.
Potential tumor-targeting peptide vector of histidylated oligolysine conjugated to a tumor-homing RGD motif.
Preclinical evaluation of transcriptional targeting strategy for human hepatocellular carcinoma in an orthotopic xenograft mouse model.
Promoter activity of SARS coronavirus 5' UTR sequence in eukaryotic cells.
Promoter characterization of the rat gene for Ca2+-binding protein regucalcin. Transcriptional regulation by signaling factors.
Protein-DNA interactions at a drug-responsive element of the human apolipoprotein A-I gene.
Pure non-dioxin-like PCB congeners suppress induction of AhR-dependent endpoints in rat liver cells.
Quaternary benzo[c]phenathridine alkaloids sanguinarine and chelerythrine do not affect transcriptional activity of aryl hydrocarbon receptor: analyses in rat hepatoma cell line H4IIE.luc.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Receptor-mediated gene delivery to HepG2 cells by ternary assemblies containing cationic liposomes and cationized asialoorosomucoid.
Recombinant High Density Lipoprotein Nanoparticles for Target-Specific Delivery of siRNA.
Regression of hepatocellular carcinoma in vitro and in vivo by radiosensitizing suicide gene therapy under the inducible and spatial control of radiation.
Regulation of cancer cell proliferation by caveolin-2 down-regulation and re-expression.
Regulation of CYP2C19 expression by estrogen receptor {alpha}: implications for estrogen-dependent inhibition of drug metabolism.
Regulation of Smad7 promoter by direct association with Smad3 and Smad4.
Regulation of the Cyp2a5 gene involves an aryl hydrocarbon receptor-dependent pathway.
Regulation of the human protein C inhibitor gene expression in HepG2 cells: role of Sp1 and AP2.
Regulation of the Lactobacillus Strains on HMGCoA Reductase Gene Transcription in Human HepG2 Cells via Nuclear Factor-?B.
Regulation of the mouse protein targeting to glycogen (PTG) promoter by the FoxA2 forkhead protein and by 3',5'-cyclic adenosine 5'-monophosphate in H4IIE hepatoma cells.
Regulation of the rat S100 beta gene expression: the role of the 2 kb 5'-upstream sequence in glial specific expression.
Regulatory sequences on the human villin gene trigger the expression of a reporter gene in a differentiating HT29 intestinal cell line.
Relative differences in aryl hydrocarbon receptor-mediated response for 18 polybrominated and mixed halogenated dibenzo-p-dioxins and -furans in cell lines from four different species.
Relative potencies of individual polychlorinated naphthalenes to induce dioxin-like responses in fish and mammalian in vitro bioassays.
Relative potencies of individual polycyclic aromatic hydrocarbons to induce dioxinlike and estrogenic responses in three cell lines.
Repurposing of the CDK inhibitor PHA-767491 as a NRF2 inhibitor drug candidate for cancer therapy via redox modulation.
Requirement of metabolic activation for estrogenic activity of Pueraria mirifica.
RNA interference may be more potent than antisense RNA in human cancer cell lines.
Role of Catechin Quinones in the Induction of EpRE-Mediated Gene Expression.
Role of catechin quinones in the induction of EpRE-mediated gene expression.
Sensitivity of virally-driven luciferase reporter plasmids to members of the steroid/thyroid/retinoid family of nuclear receptors.
Single Nucleotide Polymorphism (rs4932178) in the P1 Promoter of FURIN Is Not Prognostic to Colon Cancer.
Sp family members stimulate transcription of the hex gene via interactions with GC boxes.
Species-specific antagonism of Ah receptor action by 2,2',5,5'-tetrachloro- and 2,2',3,3'4,4'-hexachlorobiphenyl.
Species-specific transcriptional activity of synthetic flavonoids in guinea pig and mouse cells as a result of differential activation of the aryl hydrocarbon receptor to interact with dioxin-responsive elements.
Specific gene transfer mediated by galactosylated poly-L-lysine into hepatoma cells.
Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells.
Specific inhibition of hepatitis C virus replication by cyclosporin A.
Specificity of action of a herpes virus VP16/tetracycline-dependent trans-activator in mammalian cell cultures.
Stabilizing in vitro ultrasound-mediated gene transfection by regulating cavitation.
Structural and functional characterization of the 5'-flanking region of the rat and human cytochrome P450 2E1 genes: identification of a polymorphic repeat in the human gene.
Structural characterization of the human carboxypeptidase D gene and its promoter.
Structural characterization of the mouse Foxf1a gene.
Structure and promoter characterization of aldo-keto reductase family 1 B10 gene.
Structure of the gene encoding dihydrolipoyl transacylase (E2) component of human branched chain alpha-keto acid dehydrogenase complex and characterization of an E2 pseudogene.
Structure of the rat methionine adenosyltransferase 2A gene and its promoter.
Student award winner in the Ph.D. category for the 2013 society for biomaterials annual meeting and exposition, april 10-13, 2013, Boston, Massachusetts : biomaterial-mediated cancer-specific DNA delivery to liver cell cultures using synthetic poly(beta-amino ester)s.
Synergistic effect of polyethylenimine and cationic liposomes in nucleic acid delivery to human cancer cells.
TATA-less mouse vitronectin gene promoter: characterization of the transcriptional regulatory elements and a nuclear protein binding site on the promoter.
The application of reporter gene assays for the determination of the toxic potency of diffuse air pollution.
The effect of chemical carcinogenesis on rat glutathione S-transferase P1 gene transcriptional regulation.
The expression of the H19 gene and its function in human bladder carcinoma cell lines.
The inhibition effect of 2,3,7,8-tetrachlorinated dibenzo-p-dioxin-induced aryl hydrocarbon receptor activation in human hepatoma cells with the treatment of cadmium chloride.
The intratumoral administration of ferucarbotran conjugated with doxorubicin improved therapeutic effect by magnetic hyperthermia combined with pharmacotherapy in a hepatocellular carcinoma model.
The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitro.
The rat enhancer of split- and hairy-related protein-2 gene: hepatic expression, genomic structure, and promoter analysis.
The role of epoxidation and electrophile-responsive element-regulated gene transcription in the potentially beneficial and harmful effects of the coffee components cafestol and kahweol.
The role of the near upstream sequence in hypoxia-induced expression of the erythropoietin gene.
The transcription factor GATA-4 regulates cytochrome P4502C19 gene expression.
Third Generation Ah Receptor-Responsive Luciferase Reporter Plasmids: Amplification of Dioxin Responsive Elements Dramatically Increases Calux Bioassay Sensitivity and Responsiveness.
Thyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1.
Toxicity of hydroxylated and quinoid PCB metabolites: inhibition of gap junctional intercellular communication and activation of aryl hydrocarbon and estrogen receptors in hepatic and mammary cells.
Transactivation of the hepatitis B virus core promoter by the nuclear receptor FXRalpha.
Transcription factor Sp1 is necessary for basal calmodulin gene transcription and for its selective stimulation by insulin.
Transcriptional regulation of human oxysterol 7alpha-hydroxylase by sterol response element binding protein.
Two methods of heterokaryon formation to discover HCV restriction factors.
Utilization of RNA polymerase I promoter and terminator sequences to develop a DNA transfection system for the study of hepatitis C virus internal ribosomal entry site-dependent translation.
Validation of a cell culture bioassay for detection of petroleum exposure in mink (Mustela vison) as a model for detection in sea otters (Enhydra lutris).
Validity of using a relative potency factor approach for the risk management of dioxin-like polychlorinated naphthalenes.
Vanadate inhibits transcription of the rat insulin receptor gene via a proximal sequence of the 5'flanking region.
Winged helix hepatocyte nuclear factor 3 and POU-domain protein brn-2/N-oct-3 bind overlapping sites on the neuronal promoter of human aromatic L-amino acid decarboxylase gene.
[Application of secretary luciferase labeled orthotopic transplant model of hepatocellular carcinoma to evaluate tumor response to interferon-beta gene therapy].
[Construction and identification of recombinant firefly luciferase reporter plasmid pGL2-PEPCK-Luc]
[Construction of luciferase reporter plasmid which is under the control of dioxin-responsive enhancers]
[Effect of MT1M gene on the cell cycle and signaling pathway of Hep-G2]
[Effects of hepatitis B virus X gene on p21(WAF1) expression through p53-dependent and p53-independent pathways]
[Effects of hepatitis C virus core protein on activity of double-stranded RNA-dependent protein kinase].
[Establishment of an iRFP and luciferase dual-color fluorescence-traced hepatocellular carcinoma transplantation model in nude mice].
[MiR-503 sensitizes human hepatocellular carcinoma cells to cisplatin by targeting bcl-2].
[Study of cooperation of tumor suppressor p33(ING1b) with p53 gene in hepatocellular carcinoma]
[The antiandrogenic effect of dimethachlon and its mechanism]
[The effects of microRNA-7 on proliferation and invasion of hepatocellular carcinoma HepG2 cells].
Carcinoma, Lewis Lung
Cryoimmunotherapy with local co-administration of ex vivo generated dendritic cells and CpG-ODN immune adjuvant, elicits a specific antitumor immunity.
Expression of tdTomato and luciferase in a murine lung cancer alters the growth and immune microenvironment of the tumor.
Hypoxia imaging predicts success of hypoxia-induced cytosine deaminase/5-fluorocytosine gene therapy in a murine lung tumor model.
Hypoxia-induced cytosine deaminase gene expression for cancer therapy.
Intratracheal administration of a nanoparticle-based therapy with the angiotensin II type 2 receptor gene attenuates lung cancer growth.
PO-16 - ASK1 regulates tumor lung metastasis and platelet functions.
Thyroxine promotes lung cancer growth in an orthotopic mouse model.
Carcinoma, Non-Small-Cell Lung
Down-regulation of miR-675-5p contributes to tumor progression and development by targeting pro-tumorigenic GPR55 in non-small cell lung cancer.
Identification of miR-200a-5p targeting the peptide transporter TAP1 and its association with the clinical outcome of melanoma patients.
Mechanisms of platelet-activating factor-induced enhancement of VEGF expression.
MicroRNA-361-3p suppresses tumor cell proliferation and metastasis by directly targeting SH2B1 in NSCLC.
MicroRNA-944 Affects Cell Growth by Targeting EPHA7 in Non-Small Cell Lung Cancer.
Polymorphisms in the promoter region of the neutrophil elastase gene are associated with lung cancer development.
Putative association of the single nucleotide polymorphisms in RASSF1A promoter with Korean lung cancer.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Single nucleotide polymorphisms of the TGFB1 gene and lung cancer risk in a Korean population.
The Ancient Chinese Decoction Yu-Ping-Feng Suppresses Orthotopic Lewis Lung Cancer Tumor Growth Through Increasing M1 Macrophage Polarization and CD4+ T Cell Cytotoxicity.
Carcinoma, Ovarian Epithelial
The clinicopathological significance of miR-1307 in chemotherapy resistant epithelial ovarian cancer.
Carcinoma, Papillary
MIR22HG inhibits cell growth, migration and invasion through regulating the miR-24-3p/p27kip1 axis in thyroid papillary carcinomas.
Carcinoma, Renal Cell
A novel bioluminescent tumor model of human renal cancer cell lines: an in vitro and in vivo characterization.
Activation of Sp1-mediated vascular permeability factor/vascular endothelial growth factor transcription requires specific interaction with protein kinase C zeta.
Establishment and characterization of transplantable, luminescence labeled rat renal cell carcinoma cell lines.
Establishment of a bioluminescent Renca cell line for renal carcinoma research.
Hepatocyte nuclear factor (HNF)-4 alpha/gamma, HNF-1 alpha, and vHNF-1 regulate the cell-specific expression of the human dihydrodiol dehydrogenase (DD)4/AKR1C4 gene.
Hypoxia contributes to galectin-3 expression in renal carcinoma cells.
LncRNA HIF1A-AS2 accelerates malignant phenotypes of renal carcinoma by modulating miR-30a-5p/SOX4 axis as a ceRNA.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
SOX9 was involved in TKIs resistance in renal cell carcinoma via Raf/MEK/ERK signaling pathway.
The putative tumor suppressor, miR-199a, regulated by Snail, modulates clear cell renal cell carcinoma aggressiveness by repressing ROCK1.
Upregulation of microRNA-204 inhibits cell proliferation, migration and invasion in human renal cell carcinoma cells by downregulating SOX4.
Carcinoma, Squamous Cell
A functional haplotype of NFKB1 influence susceptibility to oral cancer: a population-based and in vitro study.
A soft coral natural product, 11-episinulariolide acetate, inhibits gene expression of cyclooxygenase-2 and interleukin-8 through attenuation of calcium signaling.
Antitumor potential of SLPI promoter controlled recombinant caspase-3 expression in laryngeal carcinoma.
Corynebacterium tuberculostearicum, a human skin colonizer, induces the canonical nuclear factor-?B inflammatory signaling pathway in human skin cells.
Investigation of Targeting Relationship between Micro-Rna-22 and Vegfr3 in Lung Squamous Cell Carcinoma.
Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Regulation of parathyroid hormone-related protein secretion and mRNA expression in normal human keratinocytes and a squamous carcinoma cell line.
Serum decreases the size of Metafectene-and Genejammer-DNA complexes but does not affect significantly their transfection activity in SCCVII murine squamous cell carcinoma cells.
Stabilization of G-quadruplex DNA and inhibition of Bcl-2 expression by a pyridostatin analog.
Truncating mutations of PPM1D are found in blood DNA samples of lung cancer patients.
Cardiomegaly
?-catenin/LEF1/IGF-IIR Signaling Axis Galvanizes the Angiotensin-II- induced Cardiac Hypertrophy.
BMP TYPE I RECEPTOR ALK2 IS REQUIRED FOR ANGIOTENSIN II-INDUCED CARDIAC HYPERTROPHY.
Circ_nuclear factor I X (circNfix) attenuates pressure overload-induced cardiac hypertrophy via regulating miR-145-5p/ATF3 axis.
Involvement of microRNA-23b-5p in the promotion of cardiac hypertrophy and dysfunction via the HMGB2 signaling pathway.
MicroRNAs are dynamically regulated in hypertrophic hearts, and miR-199a is essential for the maintenance of cell size in cardiomyocytes.
MiR-221 promotes cardiac hypertrophy in vitro through the modulation of p27 expression.
Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling.
Tumor necrosis factor-alpha-converting enzyme is a key regulator of agonist-induced cardiac hypertrophy and fibrosis.
Cardiomyopathies
miR-1 mediated suppression of Sorcin regulates myocardial contractility through modulation of Ca(2+) signaling.
Cardiomyopathy, Dilated
Increased Cardiac Arrhythmogenesis Associated With Gap Junction Remodeling With Upregulation of RNA-Binding Protein FXR1.
Cardiotoxicity
Investigating the effect of lncRNA HOTAIR on apoptosis induced by myocardial ischemia-reperfusion injury.
Ponatinib-induced cardiotoxicity: delineating the signaling mechanisms and potential rescue strategies.
Cardiovascular Diseases
Chromogranin B regulates calcium signaling, nuclear factor kappaB activity, and brain natriuretic peptide production in cardiomyocytes.
Cerebral Hemorrhage
MiR-7 alleviates secondary inflammatory response of microglia caused by cerebral hemorrhage through inhibiting TLR4 expression.
Cerebral Infarction
MiR-101 Protects Against the Cerebral I/R Injury Through Regulating JAK2/STAT3 Signaling Pathway.
Chickenpox
Detection of antibodies to varicella-zoster virus in recipients of the varicella vaccine by using a luciferase immunoprecipitation system assay.
Chlamydia Infections
Activation of caspase-3 during Chlamydia trachomatis-induced apoptosis at a late stage.
Cholangiocarcinoma
Down-regulation of miR-214 contributes to intrahepatic cholangiocarcinoma metastasis by targeting Twist.
LncRNA TTN-AS1 promotes the progression of cholangiocarcinoma via the miR-320a/neuropilin-1 axis.
miR-17-92 cluster promotes cholangiocarcinoma growth: evidence for PTEN as downstream target and IL-6/Stat3 as upstream activator.
Cholera
Activity of the CYP17 promoter in bovine adrenocortical cells before and after phenotypic switching.
Distinct sensory pathways in Vibrio cholerae El Tor and classical biotypes modulate cyclic dimeric GMP levels to control biofilm formation.
Expression of cholera toxin B subunit oligomers in transgenic potato plants.
Stimulation of a rat uterine stromal cell line in culture reveals a molecular switch for endocrine-dependent differentiation.
Chondrosarcoma
cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis.
miRNA-497 Negatively Regulates the Growth and Motility of Chondrosarcoma Cells by Targeting Cdc25A.
Tumor Suppressive Role of miR-342-5p in Human Chondrosarcoma Cells and 3D Organoids.
Chordoma
miR-100-5p Inhibits Malignant Behavior of Chordoma Cells by Targeting IGF1R.
Choriocarcinoma
A role for CCAAT/enhancer-binding protein beta in the basal regulation of the distal-less 3 gene promoter in placental cells.
Cis-acting elements regulating the placenta-specific promoter of the bovine Cyp19 gene.
Expression and uptake of the thyroxine-binding protein transthyretin is regulated by oxygen in primary trophoblast placental cells.
Functional promoter and polyadenylation site mapping of the human serotonin (5-HT) transporter gene.
Gene for porcine pregnancy-associated glycoprotein 2 (poPAG2): its structural organization and analysis of its promoter.
Glial Cells Missing 1 Regulates Equine Chorionic Gonadotrophin Beta Subunit via Binding to the Proximal Promoter.
Novel cyclic adenosine 3',5'-monophosphate response element in the human chorionic gonadotropin beta-subunit gene.
Overexpressed PAK4 promotes proliferation, migration and invasion of choriocarcinoma.
Positive and negative regulation of the rat vasopressin gene promoter.
Promoter characterization and genomic organization of the human breast cancer resistance protein (ATP-binding cassette transporter G2) gene.
Rat placental lactogen II gene: characterization of gene structure and placental-specific expression.
Structure of the human steroidogenic acute regulatory protein (StAR) gene: StAR stimulates mitochondrial cholesterol 27-hydroxylase activity.
The modified firefly luciferase reporter gene (luc+) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells.
Choroidal Neovascularization
MiR-505 promotes M2 polarization in choroidal neovascularization model mice by targeting Transmembrane Protein 229B.
Classical Swine Fever
A 250-nucleotide UA-rich element in the 3' untranslated region of Xenopus laevis Vg1 mRNA represses translation both in vivo and in vitro.
Development of a High-Throughput Serum Neutralization Test Using Recombinant Pestiviruses Possessing a Small Reporter Tag.
Clubfoot
[The functions of GLI3 and EN1 genes in idiopathic congenital talipes equinovarus]
Coinfection
A dual-reporter system for specific tracing of pancreatic ss-cell lines that non-invasively measures viable in vivo islet cells.
Alpha2,3 and alpha2,6 N-linked sialic acids facilitate efficient binding and transduction by adeno-associated virus types 1 and 6.
Cyclooxygenase-2 induction and prostacyclin release by protease-activated receptors in endothelial cells require cooperation between mitogen-activated protein kinase and NF-kappaB pathways.
Demonstration of the specificity of poliovirus encapsidation using a novel replicon which encodes enzymatically active firefly luciferase.
Development of a Staphylococcus aureus reporter strain with click beetle red luciferase for enhanced in vivo imaging of experimental bacteremia and mixed infections.
High level of transgene expression in cell cultures and in the mouse by replication-incompetent adenoviruses harboring modified VAI genes.
Identification of a high-efficiency baculovirus DNA replication origin that functions in insect and mammalian cells.
In vivo and in vitro analysis of electrical activity-dependent expression of muscle acetylcholine receptor genes using adenovirus.
Luciferase imaging for evaluation of oncolytic adenovirus replication in vivo.
Replication-Competent Influenza Virus and Respiratory Syncytial Virus Luciferase Reporter Strains Engineered for Co-Infections Identify Antiviral Compounds in Combination Screens.
Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: a molecular switch for control of gene expression.
Trypanosoma cruzi (Chagas' disease agent) reduces HIV-1 replication in human placenta.
Colitis
Activation of sirtuin 1 by catalpol-induced down-regulation of microRNA-132 attenuates endoplasmic reticulum stress in colitis.
Cembranoids from the Gum Resin of Boswellia carterii as Potential Antiulcerative Colitis Agents.
Clotrimazole ameliorates intestinal inflammation and abnormal angiogenesis by inhibiting interleukin-8 expression through a nuclear factor-kappaB-dependent manner.
Epithelial-derived fibronectin expression, signaling, and function in intestinal inflammation.
Fortunellin-Induced Modulation of Phosphatase and Tensin Homolog by MicroRNA-374a Decreases Inflammation and Maintains Intestinal Barrier Function in Colitis.
Mesenchymal stromal cell therapeutic potency is dependent upon viability, route of delivery, and immune match.
Colitis, Ulcerative
Activation of NF-kappaB in intestinal epithelial cells by E. coli strains isolated from the colonic mucosa of IBD patients.
Fortunellin-Induced Modulation of Phosphatase and Tensin Homolog by MicroRNA-374a Decreases Inflammation and Maintains Intestinal Barrier Function in Colitis.
Suppression of miR-330-3p alleviates DSS-induced ulcerative colitis and apoptosis by upregulating the endoplasmic reticulum stress components XBP1.
Coloboma
Sox11 is required to maintain proper levels of Hedgehog signaling during vertebrate ocular morphogenesis.
Colonic Neoplasms
5-Fluorouracil upregulates the activity of Wnt signaling pathway in CD133-positive colon cancer stem-like cells.
?-Mangostin Enhances Betulinic Acid Cytotoxicity and Inhibits Cisplatin Cytotoxicity on HCT 116 Colorectal Carcinoma Cells.
A Novel Approach for Monitoring TGF-ß Signaling in vivo in Colon Cancer.
Activatable cell penetrating peptide-peptide nucleic acid conjugate via reduction of azobenzene PEG chains.
Activation by zinc of the human gastrin gene promoter in colon cancer cells in vitro and in vivo.
Activation of NF-E2 p45-related factor-2 transcription and inhibition of intestinal tumor development by AHCC, a standardized extract of cultured Lentinula edodes mycelia.
Akt-dependent NF-kappaB activation is required for bile acids to rescue colon cancer cells from stress-induced apoptosis.
ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/?-Catenin, Notch and PI3K/Akt Signaling Pathways.
Anti-inflammatory/Anti-oxidative Stress Activities and Differential Regulation of Nrf2-Mediated Genes by Non-Polar Fractions of Tea Chrysanthemum zawadskii and Licorice Glycyrrhiza uralensis.
Anti-tumor effects of engineered mesenchymal stem cells in colon cancer model.
Anticarcinogenic Effects of Dried Citrus Peel in Colon Carcinogenesis Due to Inhibition of Oxidative Stress.
Antineoplastic therapy in colorectal cancer through proteasome inhibition.
ATG3, a Target of miR-431-5p, Promotes Proliferation and Invasion of Colon Cancer via Promoting Autophagy.
Cationic liposome coupled endostatin gene for treatment of peritoneal colon cancer.
Cationized catalase-loaded hydrogel for growth inhibition of peritoneally disseminated tumor cells.
Cellular density-dependent increases in HIF-1? compete with c-Myc to down-regulate human EP4 receptor promoter activity through Sp-1-binding region.
Characterization of a cis-acting regulatory element in the protein coding region of thymidylate synthase mRNA.
Characterization of a cis-acting regulatory element in the protein-coding region of human dihydrofolate reductase mRNA.
CircTBL1XR1/miR-424 axis regulates Smad7 to promote the proliferation and metastasis of colorectal cancer.
Cloning and characterization of the rat apobec-1 gene: a comparative analysis of gene structure and promoter usage in rat and mouse.
Colostrum whey down-regulates the expression of early and late inflammatory response genes induced by Escherichia coli and Salmonella enterica Typhimurium components in intestinal epithelial cells.
Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention.
Design and evaluation of new pH-sensitive amphiphilic cationic lipids for siRNA delivery.
Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells.
Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53.
Downregulated miR-585-3p promotes cell growth and proliferation in colon cancer by upregulating PSME3.
Epithelial to mesenchymal transition and cancer stem cell phenotypes leading to liver metastasis are abrogated by the novel TGF?1-targeting peptides P17 and P144.
Establishment of a high-throughput detection system for DNA demethylating agents.
Evaluation of bioluminescent imaging for noninvasive monitoring of colorectal cancer progression in the liver and its response to immunogene therapy.
Expression and transcriptional regulation of the human alpha1, 3-fucosyltransferase 4 (FUT4) gene in myeloid and colon adenocarcinoma cell lines.
Fascin1 Suppresses RIG-I-like Receptor Signaling and Interferon-? Production by Associating with I?B Kinase ? (IKK ?) in Colon Cancer.
Folate-PEG-folate-graft-polyethylenimine-based gene delivery.
Gene targeting approach to selectively kill colon cancer cells, with hyperactive K-Ras pathway.
Genomics, transcriptomics, proteomics, and numbers.
Hedgehog Signaling Regulates Telomerase Reverse Transcriptase in Human Cancer Cells.
HOXB9 acetylation at K27 is responsible for its suppression of colon cancer progression.
Identification and Functional Analysis of Gene Regulatory Sequences Interacting with Colorectal Tumor Suppressors.
Identification of approved and investigational drugs that inhibit hypoxia-inducible factor-1 signaling.
Identification of miR-30e* regulation of Bmi1 expression mediated by tumor-associated macrophages in gastrointestinal cancer.
Improved Detection of preclinical Colorectal Liver Metastases by High Resolution Ultrasound including Molecular Ultrasound Imaging using the targeted Contrast Agent BR55.
In vitro selection of an RNA sequence that interacts with high affinity with thymidylate synthase.
Inhibition of GTP cyclohydrolase attenuates tumor growth by reducing angiogenesis and M2-like polarization of tumor associated macrophages.
Integrated analysis identifies microRNA-195 as a suppressor of Hippo-YAP pathway in colorectal cancer.
Intraperitoneal photodynamic therapy mediated by a fullerene in a mouse model of abdominal dissemination of colon adenocarcinoma.
KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines.
LncRNA HCG11 promotes 5-FU resistance of colon cancer cells through reprogramming glucose metabolism by targeting the miR-144-3p-PDK4 axis.
LncRNA HOTAIR promotes colon cancer development by down-regulating miRNA-34a.
lncRNA MALAT1 regulates the expression level of miR-21 and interferes with the biological behavior of colon cancer cells.
Long Non-Coding RNA LEF1-AS1 Promotes Migration, Invasion and Metastasis of Colon Cancer Cells Through miR-30-5p/SOX9 Axis.
Luciferase-Based Detection of Antibodies for the Diagnosis of HPV-Associated Head and Neck Squamous Cell Carcinoma.
M2 macrophage-derived exosomal microRNA-155-5p promotes the immune escape of colon cancer by downregulating ZC3H12B.
Metronomic oral topotecan prolongs survival and reduces liver metastasis in improved preclinical orthotopic and adjuvant therapy colon cancer models.
MicroRNA-218 Inhibits Cell Cycle Progression and Promotes Apoptosis in Colon Cancer by Downregulating BMI1 Polycomb Ring Finger Oncogene.
MicroRNA-506 suppresses tumor proliferation and metastasis in colon cancer by directly targeting the oncogene EZH2.
microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis.
MicroRNA-98 Suppress Warburg Effect by Targeting HK2 in Colon Cancer Cells.
MiR-145 regulates PAK4 via the MAPK pathway and exhibits an antitumor effect in human colon cells.
miR-219a-1 inhibits colon cancer cells proliferation and invasion by targeting MEMO1.
miR-223 promotes colon cancer by directly targeting p120 catenin.
miR-328 mediates a metabolic shift in colon cancer cells by targeting SLC2A1/GLUT1.
miR-4728-3p Functions as a Tumor Suppressor in Ulcerative Colitis-associated Colorectal Neoplasia Through Regulation of Focal Adhesion Signaling.
miR-590-3p promotes colon cancer cell proliferation via Wnt/?-catenin signaling pathway by inhibiting WIF1 and DKK1.
miRNA-185 serves as a prognostic factor and suppresses migration and invasion through Wnt1 in colon cancer.
Molecular cloning of the rat intestinal trefoil factor gene. Characterization of an intestinal goblet cell-associated promoter.
Murine orthotopic model for the assessment of chemoradiotherapeutic interventions in rectal cancer.
NEAT1 siRNA Packed with Chitosan Nanoparticles Regulates the Development of Colon Cancer Cells via lncRNA NEAT1/miR-377-3p Axis.
New luminescence-based approach to measurement of luciferase gene expression reporter activity and adenosine triphosphate-based determination of cell viability.
Nitric oxide-induced down-regulation of beta-catenin in colon cancer cells by a proteasome-independent specific pathway.
O-GlcNAcylation Links Nutrition to the Epigenetic Downregulation of UNC5A during Colon Carcinogenesis.
Optimization of factors influencing the transfection efficiency of folate-PEG-folate-graft-polyethylenimine.
Regulation of AKT1 expression by beta-catenin/Tcf/Lef signaling in colorectal cancer cells.
Regulation of coagulation factor XI expression by microRNAs in the human liver.
Regulation of human Cripto-1 gene expression by TGF-beta1 and BMP-4 in embryonal and colon cancer cells.
Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells.
Regulator of Chromosome Condensation 2 Identifies High-Risk Patients within Both Major Phenotypes of Colorectal Cancer.
RIP140 Represses Intestinal Paneth Cell Differentiation and Interplays with SOX9 Signaling in Colorectal Cancer.
Roles of mitochondrial transcription factor A and microRNA?590?3p in the development of colon cancer.
Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1?/p300 Interaction.
Screening Method for Anti-Colon Cancer Drugs Using Two Sensor Cell Lines with Human ?4-Galactosyltransferase 4 Gene Promoters.
Single Nucleotide Polymorphism (rs4932178) in the P1 Promoter of FURIN Is Not Prognostic to Colon Cancer.
Species-specific antagonism of Ah receptor action by 2,2',5,5'-tetrachloro- and 2,2',3,3'4,4'-hexachlorobiphenyl.
Src-mediated activation of the human neurotensin/neuromedin N promoter.
Suppress orthotopic colon cancer and its metastasis through exact targeting and highly selective drug release by a smart nanomicelle.
Suppression of the NF??B signaling pathway in colon cancer cells by the natural compound Riccardin D from Dumortierahirsute.
Synthesis and biological evaluation of halogenated curcumin analogs as potential nuclear receptor selective agonists.
Targeted chemotherapy against intraperitoneally disseminated colon carcinoma using a cationized gelatin-conjugated HVJ envelope vector.
TET1 suppresses colon cancer proliferation by impairing ?-catenin signal pathway.
The combination of ANT2 shRNA and hNIS radioiodine gene therapy increases CTL cytotoxic activity through the phenotypic modulation of cancer cells: combination treatment with ANT2 shRNA and I-131.
The VTI1A-TCF4 colon cancer fusion protein is a dominant negative regulator of Wnt signaling and is transcriptionally regulated by intestinal homeodomain factor CDX2.
Transcriptional regulation of human beta-galactoside alpha2,6-sialyltransferase (hST6Gal I) gene in colon adenocarcinoma cell line.
Upregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer.
Using ?-Lactamase and NanoLuc Luciferase Reporter Gene Assays to Identify Inhibitors of the HIF-1 Signaling Pathway.
[Effects of NGX6 on the transcriptional activation of beta-catenin/TCF/LEF in Wnt/beta-catenin signal pathway]
Colorectal Neoplasms
?-Catenin and peroxisome proliferator-activated receptor-? coordinate dynamic chromatin loops for the transcription of vascular endothelial growth factor A gene in colon cancer cells.
A Novel Oncolytic Chimeric Orthopoxvirus Encoding Luciferase Enables Real-Time View of Colorectal Cancer Cell Infection.
Aberrant methylation of the CDH13 (H-cadherin) promoter region in colorectal cancers and adenomas.
Activation and dramatically increased cytolytic activity of tumor specific T lymphocytes after radio-frequency ablation in patients with hepatocellular carcinoma and colorectal liver metastases.
Activation of tumor-specific T lymphocytes after laser-induced thermotherapy in patients with colorectal liver metastases.
Adenovirus-mediated suicide gene therapy under the control of Cox-2 promoter for colorectal cancer.
Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones.
ATF3 Mediates Anti-Cancer Activity of Trans-10, cis-12-Conjugated Linoleic Acid in Human Colon Cancer Cells.
CircTBL1XR1/miR-424 axis regulates Smad7 to promote the proliferation and metastasis of colorectal cancer.
Coactivator-associated arginine methyltransferase 1 promotes cell growth and is targeted by microRNA-195-5p in human colorectal cancer.
Comparison of doxycycline delivery methods for Tet-inducible gene expression in a subcutaneous xenograft model.
Construction and identification of the adenoviral vector with dual reporter gene for multimodality molecular imaging.
Development of a Rapid in vivo Assay to Evaluate the Efficacy of IRE1-specific Inhibitors of the Unfolded Protein Response Using Medaka Fish.
Development of an orthotopic syngeneic murine model of colorectal cancer for use in translational research.
Down-regulation of microRNA-143 is associated with colorectal cancer progression.
Effect of aspirin on the Wnt/beta-catenin pathway is mediated via protein phosphatase 2A.
Evaluation of eicosanoids and NSAIDs as PPARgamma ligands in colorectal carcinoma cells.
Evaluation of miR-720 prognostic significance in patients with colorectal cancer.
Identification and validation of mRNA 3'untranslated regions of DNMT3B and TET3 as novel competing endogenous RNAs of the tumor suppressor PTEN.
Identification of novel small-molecule compounds that inhibit the proproliferative Kruppel-like factor 5 in colorectal cancer cells by high-throughput screening.
Increasing Cancer-Specific Gene Expression by Targeting Overexpressed ?5?1 Integrin and Upregulated Transcriptional Activity of NF-?B.
JIB-04, A Small Molecule Histone Demethylase Inhibitor, Selectively Targets Colorectal Cancer Stem Cells by Inhibiting the Wnt/?-Catenin Signaling Pathway.
LncRNA-FEZF1-AS1 Promotes Tumor Proliferation and Metastasis in Colorectal Cancer by Regulating PKM2 Signaling.
Long noncoding RNA SLC30A10 promotes colorectal tumor proliferation and migration via miR-21c/APC axis.
MicroRNA-31 Reduces Inflammatory Signaling and Promotes Regeneration in Colon Epithelium, and Delivery of Mimics in Microspheres Reduces Colitis in Mice.
MicroRNA-490-3p inhibits migration and chemoresistance of colorectal cancer cells via targeting TNKS2.
miR-148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer.
miR-155 regulates the proliferation and cell cycle of colorectal carcinoma cells by targeting E2F2.
miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5.
MiR-198 represses tumor growth and metastasis in colorectal cancer by targeting fucosyl transferase 8.
miR-24 inhibited the killing effect of natural killer cells to colorectal cancer cells by downregulating Paxillin.
miR-378a-5p inhibits the proliferation of colorectal cancer cells by downregulating CDK1.
miR-433 reduces cell viability and promotes cell apoptosis by regulating MACC1 in colorectal cancer.
miR-542-3p inhibits the growth and invasion of colorectal cancer cells through targeted regulation of cortactin.
miR-885-5p upregulation promotes colorectal cancer cell proliferation and migration by targeting suppressor of cytokine signaling.
Polymer nanoassemblies with hydrophobic pendant groups in the core induce false positive siRNA transfection in luciferase reporter assays.
Regulation of lnc-TLCD2-1 on Radiation Sensitivity of Colorectal Cancer and Comprehensive Analysis of Its Mechanism.
Regulatory single nucleotide polymorphisms (rSNPs) at the promoters 1A and 1B of the human APC gene.
Small Nuclear Ribonucleoprotein Polypeptide N Accelerates Malignant Progression and Poor Prognosis in Colorectal Cancer Transcriptionally Regulated by E2F8.
Sulforaphane inhibits growth and blocks Wnt/?-catenin signaling of colorectal cancer cells.
Targeting the NAD+ salvage pathway suppresses APC mutation-driven colorectal cancer growth and Wnt/?-catenin signaling via increasing Axin level.
Ten-eleven translocation 1 (TET1) gene is a potential target of miR-21-5p in human colorectal cancer.
The potential of 5-fluorocytosine/cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model.
[Mechanism of wnt signaling pathway regulation by a truncated mutant of axin2 in colorectal cancer.]
Communicable Diseases
Genomics, transcriptomics, proteomics, and numbers.
Luciferase immunoprecipitation systems for measuring antibodies in autoimmune and infectious diseases.
Coronary Artery Disease
Liraglutide improves atherosclerosis by regulating long non-coding RNA RMRP/miR-128-1-5P/Gadd45g axis.
Coronary Occlusion
How to optimize in vivo gene transfer to cardiac myocytes: mechanical or pharmacological procedures?
COVID-19
Antibody response to multiple antigens of SARS-CoV-2 in patients with diabetes: an observational cohort study.
Human neutralising antibodies elicited by SARS-CoV-2 non-D614G variants offer cross-protection against the SARS-CoV-2 D614G variant.
ORF8 and ORF3b antibodies are accurate serological markers of early and late SARS-CoV-2 infection.
SARS-CoV-2 NSP12 Protein Is Not an Interferon-? Antagonist.
SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.
Sensitivity in Detection of Antibodies to Nucleocapsid and Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus 2 in Patients With Coronavirus Disease 2019.
Cowpox
The vaccinia virus fusion inhibitor proteins SPI-3 (K2) and HA (A56) expressed by infected cells reduce the entry of superinfecting virus.
Crohn Disease
Activation of NF-kappaB in intestinal epithelial cells by E. coli strains isolated from the colonic mucosa of IBD patients.
Cryptococcosis
Sensitive bioluminescence imaging of fungal dissemination to the brain in mouse models of cryptococcosis.
Cushing Syndrome
An N-ethyl-N-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess.
Cystic Fibrosis
Adenovirus-mediated augmentation of cell transfection with unmodified plasmid vectors.
Enhancement of liposome-mediated gene transfer to human airway epithelial cells by replication-deficient adenovirus.
Exploitation of a very small peptide nucleic acid as a new inhibitor of miR-509-3p involved in the regulation of cystic fibrosis disease-gene expression.
Genomics, transcriptomics, proteomics, and numbers.
Mechanism of enhancement of DNA expression consequent to cointernalization of a replication-deficient adenovirus and unmodified plasmid DNA.
Cystitis, Interstitial
Combination with MS protein identification and bioassay of chromatographic fractions to identify biologically active substances from complex protein sources.
Cytomegalovirus Infections
Cytomegalovirus chemokine receptor M33 knockout reduces chronic allograft rejection in a murine aortic transplant model.
Deafness
Novel genotype-phenotype correlation of functionally characterized LMX1A variants linked to sensorineural hearing loss.
Decompression Sickness
Integration host factor and LuxR synergistically bind DNA to coactivate quorum-sensing genes in Vibrio harveyi.
Dehydration
Towards water-free biobanks: long-term dry-preservation at room temperature of desiccation-sensitive enzyme luciferase in air-dried insect cells.
Dementia
Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates.
Demyelinating Diseases
In Vivo Optical Imaging of Myelination Events in a Myelin Basic Protein Promoter-Driven Luciferase Transgenic Mouse Model.
Dengue
A quantitative luciferase-based cell-cell fusion assay to measure four-serotype dengue virus E protein-triggered membrane fusion.
Ago-2-mediated slicer activity is essential for anti-flaviviral efficacy of RNAi.
Cell type-specific mechanisms of interleukin-8 induction by dengue virus and differential response to drug treatment.
Development and characterization of a stable luciferase dengue virus for high-throughput screening.
Evaluation of a Novel Reporter Virus Neutralization Test for the Serological Diagnosis of Zika and Dengue Virus Infection.
Identification of inhibitors of dengue viral replication using replicon cells expressing secretory luciferase.
Seroprevalence of Flavivirus Neutralizing Antibodies in Thailand by High-Throughput Neutralization Assay: Endemic Circulation of Zika Virus before 2012.
Triaryl pyrazoline compound inhibits flavivirus RNA replication.
Dental Plaque
The analysis of picomole amounts of L(+)- and D(-)-lactic acid in samples of dental plaque using bacterial luciferase.
Dermatitis, Atopic
Effects of aqueous extract from red Liriope platyphylla on phthalic-anhydride-induced atopic dermatitis in Interleukin-4/Luciferase/Consensus non-coding sequence-1 transgenic mice evaluated in terms of luciferase signal and general phenotype biomarkers.
Rosmarinus officinalis L. (Rosemary) Extracts Containing Carnosic Acid and Carnosol are Potent Quorum Sensing Inhibitors of Staphylococcus aureus Virulence.
Whole-Body In Vivo Monitoring of Inflammatory Diseases Exploiting Human Interleukin 6-Luciferase Transgenic Mice.
Dermatitis, Phototoxic
Phototoxicity of flavoprotein miniSOG induced by bioluminescence resonance energy transfer in genetically encoded system NanoLuc-miniSOG is comparable with its LED-excited phototoxicity.
Diabetes Mellitus, Type 1
A luciferase immunoprecipitation assay for the detection of proinsulin/insulin autoantibodies.
Comparison of radioimmunoprecipitation with luciferase immunoprecipitation for autoantibodies to GAD65 and IA-2beta.
Comparison of radioimmunoprecipitation with luciferase immunoprecipitation for autoantibodies to GAD65 and IA-2{beta}
Novel minor HLA DR associated antigens in type 1 diabetes.
[The establishment and application of testing methods of tetraspanin 7 autoantibody in type 1 diabetes].
Diabetes Mellitus, Type 2
A Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic ?-Cells in Type 2 Diabetic Mice.
Z-4 allele upstream of the aldose reductase gene is associated with proliferative retinopathy in Japanese patients with NIDDM, and elevated luciferase gene transcription in vitro.
Diabetic Nephropathies
Inhibition of miRNA-155 Alleviates High Glucose-Induced Podocyte Inflammation by Targeting SIRT1 in Diabetic Mice.
Low expression of miR-203 promoted diabetic nephropathy via increasing TLR4.
Diphtheria
Cationic liposome-mediated expression of HIV-regulated luciferase and diphtheria toxin a genes in HeLa cells infected with or expressing HIV.
Dendritic cells support homeostatic expansion of Foxp3+ regulatory T cells in Foxp3.LuciDTR mice.
Effects of enhancer mutations on the expression of human immunodeficiency virus 1-regulated luciferase and diphtheria toxin A chain genes in transfected cells.
Gene delivery with optimized electroporation parameters shows potential for treatment of gliomas.
In vitro expression of the diphtheria toxin A-chain gene under the control of human chorionic gonadotropin gene promoters as a means of directing toxicity to ovarian cancer cell lines.
Distemper
Efficient generation of vesicular stomatitis virus (VSV)-pseudotypes bearing morbilliviral glycoproteins and their use in quantifying virus neutralising antibodies.
Down Syndrome
Silencing DSCAM-AS1 suppresses the growth and invasion of ER-positive breast cancer cells by downregulating both DCTPP1 and QPRT.
Drug-Related Side Effects and Adverse Reactions
A robust in vitro screening assay to identify NF-kappaB inhibitors for inflammatory muscle diseases.
Dyslexia
A common variant associated with dyslexia reduces expression of the KIAA0319 gene.
Encephalitis, Japanese
High-throughput neutralization assay for multiple flaviviruses based on single-round infectious particles using dengue virus type 1 reporter replicon.
In vivo dynamics of reporter Flaviviridae viruses.
Seroprevalence of Flavivirus Neutralizing Antibodies in Thailand by High-Throughput Neutralization Assay: Endemic Circulation of Zika Virus before 2012.
Encephalitis, Tick-Borne
A Sensitive Nano Luciferase Immune Complex Assay System for Highly Sensitive and Specific Detection of Antibodies Against Tick-Borne Encephalitis Virus.
High-throughput neutralization assay for multiple flaviviruses based on single-round infectious particles using dengue virus type 1 reporter replicon.
Encephalitis, Viral
Luciferase imaging of a neurotropic viral infection in intact animals.
[Development and Application of An Assay for High-throughput Antiviral Compounds Screening against Alphaviruses].
Encephalomyelitis
Absence of internal ribosome entry site-mediated tissue specificity in the translation of a bicistronic transgene.
Bioluminescence in vivo imaging of autoimmune encephalomyelitis predicts disease.
Whole-Body In Vivo Monitoring of Inflammatory Diseases Exploiting Human Interleukin 6-Luciferase Transgenic Mice.
Encephalomyelitis, Autoimmune, Experimental
Bioluminescence in vivo imaging of autoimmune encephalomyelitis predicts disease.
Whole-Body In Vivo Monitoring of Inflammatory Diseases Exploiting Human Interleukin 6-Luciferase Transgenic Mice.
Encephalomyelitis, Venezuelan Equine
In vivo imaging systems (IVIS) detection of a neuro-invasive encephalitic virus.
Rapid, non-invasive imaging of alphaviral brain infection: reducing animal numbers and morbidity to identify efficacy of potential vaccines and antivirals.
Encephalomyelitis, Western Equine
Identification of thieno[3,2-b]pyrrole derivatives as novel small molecule inhibitors of neurotropic alphaviruses.
Endometrial Neoplasms
Anti-implantation effect of 2-[piperidinoethoxyphenyl]-3-[4-hydroxyphenyl]-2H-benzo(b)pyran, a potent antiestrogenic agent in rats.
Antiestrogenic effect of 20S-protopanaxadiol and its synergy with tamoxifen on breast cancer cells.
Aquaporin-1 Plays a Crucial Role in Estrogen-Induced Tubulogenesis of Vascular Endothelial Cells.
Association of Genetic Polymorphisms in Cell-Cycle Control Genes and Susceptibility to Endometrial Cancer Among Chinese Women.
Associations between a single nucleotide polymorphism of stress-induced phosphoprotein 1 and endometriosis/adenomyosis.
Direct interaction of the Krüppel-like family (KLF) member, BTEB1, and PR mediates progesterone-responsive gene expression in endometrial epithelial cells.
Estrogen and estrogen receptor induce matrix metalloproteinase-26 expression in endometrial carcinoma cells.
Functional effects of the MLH1-93G>A polymorphism on MLH1/EPM2AIP1 promoter activity.
Generation and characterization of orthotopic murine models for endometrial cancer.
LncRNA-GAS5 induces PTEN expression through inhibiting miR-103 in endometrial cancer cells.
microRNA-103 regulates the growth and invasion of endometrial cancer cells through the downregulation of tissue inhibitor of metalloproteinase 3.
MicroRNA-200b is overexpressed in endometrial adenocarcinomas and enhances MMP2 activity by downregulating TIMP2 in human endometrial cancer cell line HEC-1A cells.
MicroRNA?21?5p promotes epithelial to mesenchymal transition by targeting SRY?box 17 in endometrial cancer.
miR-15b-3p promotes the malignant progression of endometrial cancer cells through targeting KLF2.
MiR-200a and miR-200b target PTEN to regulate the endometrial cancer cell growth in vitro.
The aryl hydrocarbon receptor (AHR)/AHR nuclear translocator (ARNT) heterodimer interacts with naturally occurring estrogen response elements.
Endometriosis
Functional MicroRNA Involved in Endometriosis.
Functional polymorphism within NUP210 encoding for nucleoporin GP210 is associated with the risk of endometriosis.
Increased exposure to dioxin-like compounds is associated with endometriosis in a case-control study in women.
MicroRNA23a and MicroRNA23b Deregulation Derepresses SF-1 and Upregulates Estrogen Signaling in Ovarian Endometriosis.
Nuclear peroxisome proliferator-activated receptors alpha and gamma have opposing effects on monocyte chemotaxis in endometriosis.
Peroxisome proliferator-activated receptor-? coactivator 1?-mediated pathway as a possible therapeutic target in endometriosis.
Endotoxemia
Canscora lucidissima, a Chinese folk medicine, exerts anti-inflammatory activities by inhibiting the phosphorylation of ERK1/2 in LPS-activated macrophages.
Epidermodysplasia Verruciformis
E7 proteins of four groups of human papillomaviruses, irrespective of their tissue tropism or cancer association, possess the ability to transactivate transcriptional promoters E2F site dependently.
Epilepsy
miR-135a-5p inhibitor protects glial cells against apoptosis via targeting SIRT1 in epilepsy.
miR-21-5p protects hippocampal neurons of epileptic rats via inhibiting STAT3 expression.
Esophageal Neoplasms
Cancer-associated Fibroblast-promoted LncRNA DNM3OS Confers Radioresistance by Regulating DNA Damage Response in Esophageal Squamous Cell Carcinoma.
Genetic variant in CASP3 affects promoter activity and risk of esophageal squamous cell carcinoma.
Inhibition of Growth of Esophageal Cancer by Alantolactone via Wnt/?Catenin Signaling.
Inhibition of SOX17 by MicroRNA-141 and Methylation Activates the WNT Signaling Pathway in Esophageal Cancer.
MicroRNA-20b (miR-20b) Promotes the Proliferation, Migration, Invasion, and Tumorigenicity in Esophageal Cancer Cells via the Regulation of Phosphatase and Tensin Homologue Expression.
miR-486 functions as a tumor suppressor in esophageal cancer by targeting CDK4/BCAS2.
Stable silencing of dll4 gene suppresses the growth and metastasis of esophagus cancer cells by attenuating Akt phosphorylation.
The cluster of miR-143 and miR-145 affects the risk for esophageal squamous cell carcinoma through co-regulating fascin homolog 1.
Transcription factor OCT4 promotes cell cycle progression by regulating CCND1 expression in esophageal carcinoma.
Transcriptional activity of the tandem repeat polymorphism in the 5'-flanking region of the human CYP2E1 gene.
[Enhancement by hypoxia of antisense VEGF(165) gene expression in esophageal cancer cells]
Esophageal Squamous Cell Carcinoma
The cluster of miR-143 and miR-145 affects the risk for esophageal squamous cell carcinoma through co-regulating fascin homolog 1.
Essential Hypertension
[Association between CACNB2 gene polymorphisms and essential hypertension].
Extranodal Extension
Targeted chemotherapy against intraperitoneally disseminated colon carcinoma using a cationized gelatin-conjugated HVJ envelope vector.
Feline Panleukopenia
Species specificity for transduction of cultured cells by a recombinant LuIII rodent parvovirus genome encapsidated by canine parvovirus or feline panleukopenia virus.
Fibrosarcoma
Actinopyrone D, a new downregulator of the molecular chaperone GRP78 from Streptomyces sp.
Activation of Sp1-mediated vascular permeability factor/vascular endothelial growth factor transcription requires specific interaction with protein kinase C zeta.
Cell-penetrating peptide-conjugated lipid nanoparticles for siRNA delivery.
Changing electrode orientation, but not pulse polarity, increases the efficacy of gene electrotransfer to tumors in vivo.
Efrapeptin J, a new down-regulator of the molecular chaperone GRP78 from a marine Tolypocladium sp.
Human U6 promoter drives stronger shRNA activity than its schistosome orthologue in Schistosoma mansoni and human fibrosarcoma cells.
Localization of silencer and enhancer elements in the human type X collagen gene.
MicroRNA silencing improves the tumor specificity of adenoviral transgene expression.
Monitoring luciferase-labeled cancer cell growth and metastasis in different in vivo models.
Promoter characterization of the novel human matrix metalloproteinase-26 gene: regulation by the T-cell factor-4 implies specific expression of the gene in cancer cells of epithelial origin.
Resistance to heat radiosensitization and protein damage in thermotolerant and thermoresistant cells.
Schistosoma mansoni U6 gene promoter-driven short hairpin RNA induces RNA interference in human fibrosarcoma cells and schistosomules.
Sequence and time dependence of transfection efficiency of electrically-assisted gene delivery to tumors in mice.
Simvastatin suppresses tissue factor expression and increases fibrinolytic activity in tumor necrosis factor-alpha-activated human peritoneal mesothelial cells.
The eta isoform of protein kinase C mediates transcriptional activation of the human transglutaminase 1 gene.
Tumor suppressive activity of PIWI-interacting RNA in human fibrosarcoma mediated through repression of RRM2.
Filariasis
In vivo imaging of transgenic Brugia malayi.
Food Hypersensitivity
Cross-allergenicity of crustacean and the edible insect Gryllus bimaculatus in patients with shrimp allergy.
Foot-and-Mouth Disease
A replication-competent foot-and-mouth disease virus expressing a luciferase reporter.
Early detection and visualization of human adenovirus serotype 5-viral vectors carrying foot-and-mouth disease virus or luciferase transgenes in cell lines and bovine tissues.
Evaluation of Gaussia luciferase and foot-and-mouth disease virus 2A translational interrupter chimeras as polycistronic reporters for transgene expression.
Promotion of viral IRES-mediated translation under amino acid starvation.
Relevance of the N-terminal and major hydrophobic domains of non-structural protein 3A in the replicative process of a DNA-launched foot-and-mouth disease virus replicon.
Suicidal gene therapy in the effective control of primary human hepatocellular carcinoma as monitored by noninvasive bioimaging.
Fowlpox
Expression of target genes by coinfection with replication-deficient viral vectors.
Fragile X Syndrome
One-Step Generation of Seamless Luciferase Gene Knockin Using CRISPR/Cas9 Genome Editing in Human Pluripotent Stem Cells.
Frontotemporal Dementia
A minimal length between tau exon 10 and 11 is required for correct splicing of exon 10.
Gastritis
Archidendron lucidum Exerts Anti-Inflammatory Effects by Targeting PDK1 in the NF- ? B Pathway.
Viburnum pichinchense methanol extract exerts anti-inflammatory effects via targeting the NF-?B and caspase-11 non-canonical inflammasome pathways in macrophages.
Gastroenteritis
Porcine transmissible gastroenteritis virus nonstructural protein 2 contributes to inflammation via NF-?B activation.
Gastroschisis
Donor mesenchymal stem cell kinetics after transamniotic stem cell therapy (TRASCET) in a rodent model of gastroschisis.
Giardiasis
Methionyl-tRNA synthetase inhibitor has potent in vivo activity in a novel Giardia lamblia luciferase murine infection model.
Glioblastoma
A functional variant on 20q13.33 related to glioma risk alters enhancer activity and modulates expression of multiple genes.
A genome-wide miRNA screen revealed miR-603 as a MGMT-regulating miRNA in glioblastomas.
A novel technique of serial biopsy in mouse brain tumour models.
Activation of NFAT signal by p53-K120R mutant.
Activation of telomerase by human cytomegalovirus.
Activation of the Wnt Pathway by Small Peptides: Rational Design, Synthesis and Biological Evaluation.
Apolipoprotein E isoform dependently affects Tat-mediated HIV-1 LTR transactivation.
Assessment of cetuximab efficacy by bioluminescence monitoring of intracranial glioblastoma xenograft in mouse.
Bioluminescence imaging reveals inhibition of tumor cell proliferation by Alzheimer's amyloid beta protein.
Characterization of a brain-specific Sp1-like activity interacting with an unusual binding site within the myelin proteolipid protein promoter.
De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures.
Dehydroleucodine Induces a TP73-dependent Transcriptional Regulation of Multiple Cell Death Target Genes in Human Glioblastoma Cells.
Detection of Brain Tumors and Systemic Metastases Using NanoLuc and Fluc for Dual Reporter Imaging.
Dual systemic tumor targeting with ligand-directed phage and Grp78 promoter induces tumor regression.
Efficacy of interstitial continuous vincristine infusion in a bioluminescent rodent intracranial tumor model.
Efficacy of vincristine administered via convection-enhanced delivery in a rodent brainstem tumor model documented by bioluminescence imaging.
Fluorine-19 nuclear magnetic resonance of chimeric antigen receptor T cell biodistribution in murine cancer model.
Functional assessment of a promoter polymorphism in S100B, a putative risk variant for bipolar disorder.
Functional characterization of the brain-specific FGF-1 promoter, FGF-1.B.
Glucocorticoid and androgen activation of monoamine oxidase A is regulated differently by R1 and Sp1.
In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers.
Influence of promoter/enhancer region haplotypes on MGMT transcriptional regulation: a potential biomarker for human sensitivity to alkylating agents.
INSM1 Promoter-Driven Adenoviral Herpes Simplex Virus Thymidine Kinase Cancer Gene Therapy for the Treatment of Primitive Neuroectodermal Tumors.
Knockdown of lncRNA-UCA1 inhibits cell viability and migration of human glioma cells by miR-193a-mediated downregulation of CDK6.
Late temporal gene expression from the human cytomegalovirus pp28US (UL99) promoter when integrated into the host cell chromosome.
Long non-coding RNA HOTAIRM1 promotes proliferation and inhibits apoptosis of glioma cells by regulating the miR-873-5p/ZEB2 axis.
MicroRNA-1908 functions as a glioblastoma oncogene by suppressing PTEN tumor suppressor pathway.
MiR-29a Inhibits Glioma Tumorigenesis through a Negative Feedback Loop of TRAF4/Akt Signaling.
miR-340 inhibits glioblastoma cell proliferation by suppressing CDK6, cyclin-D1 and cyclin-D2.
miR-663 Suppresses Oncogenic Function of CXCR4 in Glioblastoma.
miR-7-5p inhibits cell migration and invasion in glioblastoma through targeting SATB1.
Multifunctional cationic lipid-based nanoparticles facilitate endosomal escape and reduction-triggered cytosolic siRNA release.
Noninvasive monitoring of pharmacodynamics and kinetics of a death receptor 5 antibody and its enhanced apoptosis induction in sequential application with doxorubicin.
Novel anti-apoptotic microRNAs 582-5p and 363 promote human glioblastoma stem cell survival via direct inhibition of caspase 3, caspase 9, and Bim.
Pharmacologic Wnt Inhibition Reduces Proliferation, Survival, and Clonogenicity of Glioblastoma Cells.
Post-translational regulation of gene expression using the ATF4 oxygen-dependent degradation domain for hypoxia-specific gene therapy.
Pyridylthiourea-grafted polyethylenimine offers an effective assistance to siRNA-mediated gene silencing in vitro and in vivo.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Regulation of p27Kip1 by miRNA 221/222 in glioblastoma.
Sohlh1 suppresses glioblastoma cell proliferation, migration, and invasion by inhibition of Wnt/?-catenin signaling.
Stable luciferase expression does not alter immunologic or in vivo growth properties of GL261 murine glioma cells.
Targeted Brain Tumor Therapy by Inhibiting the MDM2 Oncogene: In Vitro and In Vivo Antitumor Activity and Mechanism of Action.
Transcription factors Zic1 and Zic2 bind and transactivate the apolipoprotein E gene promoter.
Glioma
A combination of IFN-beta and temozolomide in human glioma xenograft models: implication of p53-mediated MGMT downregulation.
A Myristoylated Cell-Penetrating Peptide Bearing a Transferrin Receptor-Targeting Sequence for Neuro-Targeted siRNA Delivery.
A redshifted codon-optimized firefly luciferase is a sensitive reporter for bioluminescence imaging.
Abnormal increase of miR-4262 promotes cell proliferation and migration by targeting large tumor suppressor 1 in gliomas.
Activation of telomerase by human cytomegalovirus.
Activation of the radiosensitive EGR-1 promoter induces expression of the herpes simplex virus thymidine kinase gene and sensitivity of human glioma cells to ganciclovir.
Activator-protein-1 binding potentiates the hypoxia-induciblefactor-1-mediated hypoxia-induced transcriptional activation of vascular-endothelial growth factor expression in C6 glioma cells.
Activity of the rat GluR4 promoter in transfected cortical neurons and glia.
AdipoR1-mediated miR-3908 inhibits glioblastoma tumorigenicity through downregulation of STAT2 associated with the AMPK/SIRT1 pathway.
An insertion variant of MGMT disrupts a STAT1 binding site and confers susceptibility to glioma.
Anti-miRNA-23a Oligonucleotide Suppresses Glioma Cells Growth by Targeting Apoptotic Protease Activating Factor-1.
Anti-PD-1 Blockade and Stereotactic Radiation Produce Long-Term Survival in Mice With Intracranial Gliomas.
Anti-PD-L1 antibody direct activation of macrophages contributes to a radiation-induced abscopal response in glioblastoma.
Antisense imaging of gene expression in the brain in vivo.
Bioluminescence Imaging of an Immunocompetent Animal Model for Glioblastoma.
Blocking lncRNA MALAT1/miR-199a/ZHX1 Axis Inhibits Glioblastoma Proliferation and Progression.
Brain and testis selective expression of the glutathione S-transferase Yb3 subunit is governed by tandem direct repeat octamer motifs in the 5'-flanking region of its gene.
CACNA2D3 is downregulated in gliomas and functions as a tumor suppressor.
Characterization of Infectivity of Knob-Modified Adenoviral Vectors in Glioma.
Chlorotoxin fusion protein regulates miR-374a and TNFAIP8 expression and inhibits glioma cell proliferation and promotes apoptosis.
Circ-RPL15/miR-146b-3p/VEGFA feedback loop is responsible for triggering proliferation and migration in glioma.
Circadian rhythm generation in a glioma cell line.
Circular RNA circ_001350 regulates glioma cell proliferation, apoptosis, and metastatic properties by acting as a miRNA sponge.
Cis-element/cytoplasmic protein interaction within the 3'-untranslated region of the GLUT1 glucose transporter mRNA.
Cloning and characterization of the human and rabbit NUDEL-oligopeptidase promoters and their negative regulation.
Cloning of the rat fibroblast growth factor-2 promoter region and its response to mitogenic stimuli in glioma C6 cells.
Codon-Optimized Luciola italica Luciferase Variants for Mammalian Gene Expression in Culture and In Vivo.
Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma.
Combined targeting of adenoviruses to integrins and epidermal growth factor receptors increases gene transfer into primary glioma cells and spheroids.
Comparative evaluation of survivin, midkine and CXCR4 promoters for transcriptional targeting of glioma gene therapy.
Comprehensive Transcriptomic Analysis and Experimental Validation Identify lncRNA HOXA-AS2/miR-184/COL6A2 as the Critical ceRNA Regulation Involved in Low-Grade Glioma Recurrence.
Correlation of Glioma Proliferation and Hypoxia by Luciferase, Magnetic Resonance, and Positron Emission Tomography Imaging.
Cytoskeleton-associated protein 4 (CKAP4) promotes malignant progression of human gliomas through inhibition of the Hippo signaling pathway.
Delivery of bevacizumab by intracranial injection: assessment in glioma model.
Downregulation of hsa_circ_0000936 sensitizes resistant glioma cells to temozolomide by sponging miR-1294.
Dysregulation of microRNA-128 expression in WHO grades 2 glioma is associated with glioma-associated epilepsy: Down-regulation of miR-128 induces glioma-associated seizure.
E2F2 drives glioma progression via PI3K/AKT in a PFKFB4-dependent manner.
Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms.
Effect of brain- and tumor-derived connective tissue growth factor on glioma invasion.
Effect of lncRNA ANRIL silencing on anoikis and cell cycle in human glioma via microRNA-203a.
Epigenetic regulation of CD133/PROM1 expression in glioma stem cells by Sp1/myc and promoter methylation.
Epigenetic silencing of miR-338 facilitates glioblastoma progression by de-repressing the pyruvate kinase M2-?-catenin axis.
Expression-based discovery of variation in the human glutathione S-transferase M3 promoter and functional analysis in a glioma cell line using allele-specific chromatin immunoprecipitation.
EZH2-mediated H3K27me3 enrichment on the lncRNA MEG3 promoter regulates the growth and metastasis of glioma cells by regulating miR-21-3p.
Flot2 targeted by miR-449 acts as a prognostic biomarker in glioma.
FOXA1 is upregulated in glioma and promotes proliferation as well as cell cycle through regulation of cyclin D1 expression.
Generation of bidirectional hypoxia/HIF-responsive expression vectors to target gene expression to hypoxic cells.
GL261 luciferase-expressing cells elicit an anti-tumor immune response: an evaluation of murine glioma models.
GLIDR promotes the progression of glioma by regulating the miR-4677-3p/MAGI2 axis.
HLF/miR-132/TTK axis regulates cell proliferation, metastasis and radiosensitivity of glioma cells.
Hsa-miR-495 acts as a tumor suppressor gene in glioma via the negative regulation of MYB.
Hsa_circ_0091581 promotes glioma progression by regulating RMI1 via sponging miR-1243-5p.
Hu Antigen R (HuR) multimerization contributes to glioma disease progression.
Hypoxia-inducible miR-196a modulates glioblastoma cell proliferation and migration through complex regulation of NRAS.
Identification of a promoter region in the rat prion protein gene.
Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.
In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats.
Increased oncolytic efficacy for high-grade gliomas by optimal integration of ionizing radiation into the replicative cycle of HSV-1.
iNOS expression inhibits hypoxia-inducible factor-1 activity.
Intratumoral delivery of bortezomib: impact on survival in an intracranial glioma tumor model.
Kaiso (ZBTB33) Downregulation by Mirna-181a Inhibits Cell Proliferation, Invasion, and the Epithelial-Mesenchymal Transition in Glioma Cells.
LINC00210 exerts oncogenic roles in glioma by sponging miR-328.
LncRNA CCAT2 promotes angiogenesis in glioma through activation of VEGFA signalling by sponging miR-424.
LncRNA FAM181A-AS1 promotes gliomagenesis by sponging miR-129-5p and upregulating ZRANB2.
LncRNA NEAT1 Enhances Glioma Progression via Regulating the miR-128-3p/ITGA5 Axis.
Long non-coding RNA H19 promotes proliferation and invasion in human glioma cells by downregulating miR-152.
Long Non-Coding RNA PART1 Exerts Tumor Suppressive Functions in Glioma via Sponging miR-190a-3p and Inactivation of PTEN/AKT Pathway.
Long non-coding RNA TUG1 acts as a miR-26a sponge in human glioma cells.
Long non-coding RNA ZEB1-AS1 promotes glioma cell proliferation, migration and invasion through regulating miR-577.
Long non?coding RNA ferritin heavy polypeptide 1 pseudogene 3 controls glioma cell proliferation and apoptosis via regulation of the microRNA?224?5p/tumor protein D52 axis.
Long noncoding RNA DLEU1 aggravates glioma progression via the miR-421/MEF2D axis.
Long noncoding RNA GACAT3 promotes glioma progression by sponging miR-135a.
Loss of NECL1, a novel tumor suppressor, can be restored in glioma by HDAC inhibitor-Trichostatin A through Sp1 binding site.
Marked enhancement in gene expression by targeting the human insulin receptor.
Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal.
MicroRNA-101 inhibits proliferation, migration and invasion of human glioblastoma by targeting SOX9.
MicroRNA-129-5p inhibits human glioma cell proliferation and induces cell cycle arrest by directly targeting DNMT3A.
MicroRNA-133a inhibits the malignant behavior of glioma via downregulation of matrix metallopeptidase 9.
MicroRNA-139-5p acts as a tumor suppressor by targeting ELTD1 and regulating cell cycle in glioblastoma multiforme.
MicroRNA-145 is downregulated in glial tumors and regulates glioma cell migration by targeting connective tissue growth factor.
MicroRNA-153 suppresses cell invasion by targeting SNAI1 and predicts patient prognosis in glioma.
MicroRNA-155 promotes glioma cell proliferation via the regulation of MXI1.
MicroRNA-155-3p promotes glioma progression and temozolomide resistance by targeting Six1.
MicroRNA-183 upregulates HIF-1? by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells.
MicroRNA-202 inhibits cell proliferation, migration and invasion of glioma by directly targeting metadherin.
MicroRNA-370-3p inhibits human glioma cell proliferation and induces cell cycle arrest by directly targeting ?-catenin.
MicroRNA-384 inhibits proliferation migration and invasion of glioma by targeting at CDC42.
MicroRNA-610 is downregulated in glioma cells, and inhibits proliferation and motility by directly targeting MDM2.
MicroRNA-675 promotes glioma cell proliferation and motility by negatively regulating retinoblastoma 1.
MicroRNA-7 directly targets insulin-like growth factor 1 receptor to inhibit cellular growth and glucose metabolism in gliomas.
MicroRNA-769-3p inhibits tumor progression in glioma by suppressing ZEB2 and inhibiting the Wnt/?-catenin signaling pathway.
MicroRNA?138 modulates glioma cell growth, apoptosis and invasion through the suppression of the AKT/mTOR signalling pathway by targeting CREB1.
microRNA?205 acts as a tumor suppressor and directly targets YAP1 in glioma.
Minimal and inducible regulation of tissue factor pathway inhibitor-2 in human gliomas.
miR-106b-5p Inhibits IRF1/IFN-? Signaling to Promote M2 Macrophage Polarization of Glioblastoma.
MiR-129-2 functions as a tumor suppressor in glioma cells by targeting HMGB1 and is down-regulated by DNA methylation.
miR-133b inhibits glioma cell proliferation and invasion by targeting Sirt1.
miR-135a inhibits glioma cell proliferation and invasion by directly targeting FOXO1.
miR-141-3p functions as a tumor suppressor modulating activating transcription factor 5 in glioma.
miR-200b is a key regulator of tumor progression and metabolism targeting lactate dehydrogenase A in human malignant glioma.
miR-203 sensitizes glioma cells to temozolomide and inhibits glioma cell invasion by targeting E2F3.
MiR-205 enhances cisplatin sensitivity of glioma cells by targeting E2F1.
MiR-206 is down-regulated and suppresses cell proliferation by targeting FOXP1 in brain gliomas.
MiR-218 Inhibited Growth and Metabolism of Human Glioblastoma Cells by Directly Targeting E2F2.
miR-29a-5p Regulates the Proliferation, Invasion, and Migration of Gliomas by Targeting DHRS4.
MiR-301a is activated by the Wnt/?-catenin pathway and promotes glioma cell invasion by suppressing SEPT7.
miR-30a inhibits glioma progression and stem cell?like properties by repression of Wnt5a.
MiR-320 inhibits the growth of glioma cells through downregulating PBX3.
MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation.
MiR-338 suppresses cell proliferation and invasion by targeting CTBP2 in glioma.
MiR-379-5p targets microsomal glutathione transferase 1 (MGST1) to regulate human glioma in cell proliferation, migration and invasion and epithelial-mesenchymal transition (EMT).
MiR-410 regulates MET to influence the proliferation and invasion of glioma.
miR-423-5p contributes to a malignant phenotype and temozolomide chemoresistance in glioblastomas.
miR-454-3p Is an Exosomal Biomarker and Functions as a Tumor Suppressor in Glioma.
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-?-catenin pathway.
miR-505 functions as a tumor suppressor in glioma by targeting insulin like growth factor 1 receptor expression.
miR-548b inhibits the proliferation and invasion of malignant gliomas by targeting metastasis tumor-associated protein-2.
miR-590-3p promotes colon cancer cell proliferation via Wnt/?-catenin signaling pathway by inhibiting WIF1 and DKK1.
MiR-616 promotes proliferation and inhibits apoptosis in glioma cells by suppressing expression of SOX7 via the Wnt signaling pathway.
miR-6869-5p Inhibits Glioma Cell Proliferation and Invasion via Targeting PGK1.
MiR-873 acts as a novel sensitizer of glioma cells to cisplatin by targeting Bcl-2.
MiR-9-3p augments apoptosis induced by H2O2 through down regulation of Herpud1 in glioma.
miR-92b controls glioma proliferation and invasion through regulating Wnt/beta-catenin signaling via Nemo-like kinase.
MiR-98 Promotes Apoptosis of Glioma Cells via Suppressing IKBKE/NF-?B Pathway.
miR?378a?3p inhibits cellular proliferation and migration in glioblastoma multiforme by targeting tetraspanin 17.
miRNA-193a-3p Regulates the AKT2 Pathway to Inhibit the Growth and Promote the Apoptosis of Glioma Cells by Targeting ALKBH5.
miRNA-451 regulates the NF-?B signaling pathway by targeting IKK? to inhibit glioma cell growth.
Monitoring autophagic flux using p62/SQSTM1 based luciferase reporters in glioma cells.
NCK1-AS1 Increases Drug Resistance of Glioma Cells to Temozolomide by Modulating miR-137/TRIM24.
NF-?B-mediated miR-650 plays oncogenic roles and activates AKT/ERK/NF-?B pathways by targeting RERG in glioma cells.
NO-mediated chemoresistance in C6 glioma cells.
Noninvasive Monitoring of Glioma Growth in the Mouse.
Novel internal regulators and candidate miRNAs within miR-379/miR-656 miRNA cluster can alter cellular phenotype of human glioblastoma.
Novel recombinant adenoviral vector that targets the interleukin-13 receptor alpha2 chain permits effective gene transfer to malignant glioma.
Nuclear Translocation of ?-catenin is Essential for Glioma Cell Survival.
Positive and negative elements contribute to the cell-specific expression of the rat dopamine beta-hydroxylase gene.
Potent and sustained inhibition of HIF-1? and downstream genes by a polyethyleneglycol-SN38 conjugate, EZN-2208, results in anti-angiogenic effects.
Potent antitumor effect of SN-38-incorporating polymeric micelle, NK012, against malignant glioma.
Promoter analysis and characteristics of the 5'-untranslated region of the mouse glial cell line-derived neurotrophic factor gene.
Promoter regions involved in density-dependent regulation of basic fibroblast growth factor gene expression in human astrocytic cells.
Regression of glioma tumor growth in F98 and U87 rat glioma models by the Nitrone OKN-007.
Regulation of cancer cell proliferation by caveolin-2 down-regulation and re-expression.
Regulation of mouse neuropeptide Y Y1 receptor gene transcription: a potential role for nuclear factor-kappa B/Rel proteins.
Role of microRNAs Located on Chromosome Arm 10q in Malignant Gliomas.
Silica cloaking of adenovirus enhances gene delivery while reducing immunogenicity.
siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencing.
Site-directed deletion of a 10-nucleotide domain of the 3'-untranslated region of the GLUT1 glucose transporter mRNA eliminates cytosolic protein binding in human brain tumors and induction of reporter gene expression.
Stable luciferase expression does not alter immunologic or in vivo growth properties of GL261 murine glioma cells.
Targeting effect of microRNA on CD133 and its impact analysis on proliferation and invasion of glioma cells.
Ten nucleotide cis element in the 3'-untranslated region of the GLUT1 glucose transporter mRNA increases gene expression via mRNA stabilization.
Tetracycline-controlled expression but not toxicity of an attenuated diphtheria toxin mutant.
The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma.
The lncRNA-DLEU2/miR-186-5p/PDK3 axis promotes the progress of glioma cells.
The long non-coding RNA SNHG1 promotes glioma progression by competitively binding to miR-194 to regulate PHLDA1 expression.
The long non-coding RNA SNHG14 inhibits cell proliferation and invasion and promotes apoptosis by sponging miR-92a-3p in glioma.
The major promoter of the rat insulin-like growth factor-I gene binds a protein complex that is required for basal expression.
Transactivation by Runt related factor-2 of matrix metalloproteinase-13 in astrocytes.
Transcription of the rat dopamine-D2-receptor gene from two promoters.
Transcriptional regulation of ceruloplasmin by an IL-6 response element pathway.
Transcriptional regulation of P450scc gene expression in neural and steroidogenic cells: implications for regulation of neurosteroidogenesis.
Tumor suppressor microRNA?613 inhibits glioma cell proliferation, invasion and angiogenesis by targeting vascular endothelial growth factor A.
UCHL1 enhances the malignant development of glioma via targeting GAS2.
Valproate robustly enhances AP-1 mediated gene expression.
Variability of transcriptional regulation after gene transfer with the retroviral tetracycline system.
Visualization of hypoxia-inducible factor-1 transcriptional activation in C6 glioma using luciferase and sodium iodide symporter genes.
Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo.
Gliosarcoma
An experimental brainstem tumor model using in vivo bioluminescence imaging in rat.
Longitudinal assessment of regional directed delivery in a rodent malignant glioma model.
Glomerulonephritis
Enhanced expression of selenocysteine lyase in acute glomerulonephritis and its regulation by AP-1.
Glycosuria
Effects of plasmid DNA injection on cyclophosphamide-accelerated diabetes in NOD mice.
Granuloma
Live imaging of collagen deposition during experimental hepatic schistosomiasis and recovery: a view on a dynamic process.
Graves Disease
Detection of functionally different types of pathological autoantibodies against thyrotropin receptor in Graves' patients sera by luminescent immunoprecipitation analysis.
Head and Neck Neoplasms
Conditionally replicating adenovirus improves gene replication efficiency and anticancer effect of E1-deleted adenovirus carrying TRAIL in head and neck squamous cell carcinoma.
Identification of GPR65, a novel regulator of matrix metalloproteinases using high through-put screening.
Loss of interferon-gamma inducibility of the MHC class II antigen processing pathway in head and neck cancer: evidence for post-transcriptional as well as epigenetic regulation.
Silk-elastinlike protein polymer hydrogels for localized adenoviral gene therapy of head and neck tumors.
Heart Diseases
Increased Cardiac Arrhythmogenesis Associated With Gap Junction Remodeling With Upregulation of RNA-Binding Protein FXR1.
Heart Failure
circSnx12 Is Involved in Ferroptosis During Heart Failure by Targeting miR-224-5p.
Effect of empagliflozin on cardiac biomarkers in a zebrafish model of heart failure: clues to the EMPA-REG OUTCOME trial?
MicroRNA-143 modulates the expression of Natriuretic Peptide Receptor 3 in cardiac cells.
Plasmid-based transient human stromal cell-derived factor-1 gene transfer improves cardiac function in chronic heart failure.
Heart Neoplasms
LncRNA H19 interacted with miR-130a-3p and miR-17-5p to modify radio-resistance and chemo-sensitivity of cardiac carcinoma cells.
Hemangioblastoma
Site-directed deletion of a 10-nucleotide domain of the 3'-untranslated region of the GLUT1 glucose transporter mRNA eliminates cytosolic protein binding in human brain tumors and induction of reporter gene expression.
Hematologic Neoplasms
Genomics, transcriptomics, proteomics, and numbers.
Hemophilia B
Efficient transfection of primary cells in a canine hemophilia B model using adenovirus-polylysine-DNA complexes.
Etranacogene dezaparvovec (AMT-061 phase 2b): normal/near normal FIX activity and bleed cessation in hemophilia B.
Hemorrhagic Septicemia, Viral
Differential response of the Senegalese sole (Solea senegalensis) Mx promoter to viral infections in two salmonid cell lines.
Hepatitis
Characterization of cell-surface determinants important for baculovirus infection.
The critical role of myeloid-derived suppressor cells and FXR activation in immune-mediated liver injury.
Treatment of murine fulminant hepatitis with genetically engineered endothelial progenitor cells.
Woodchuck hepatitis virus post-transcriptional regulation element enhances transgene expression from adenovirus vectors.
Hepatitis B
A mouse model for studying the clearance of hepatitis B virus in vivo using a luciferase reporter.
Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication.
Construction of a highly-active, liver-specific transcriptional regulatory element through combination of the albumin promoter and ?-fetoprotein enhancer.
Construction of a replication-competent hepatitis B virus vector carrying secreted luciferase transgene and establishment of new hepatitis B virus replication and expression cell lines.
Differentiation-specific transcriptional regulation of the hepatitis B virus large surface antigen gene in human hepatoma cell lines.
Fluorogenic RNA nanoparticles for monitoring RNA folding and degradation in real time in living cells.
Hepatitis B virus core protein enhances human telomerase reverse transcriptase expression and hepatocellular carcinoma cell proliferation in a c-Ets2-dependent manner.
Hepatitis B virus inhibits the expression of CD82 through hypermethylation of its promoter in hepatoma cells.
Hepatitis B virus-induced hFGL2 transcription is dependent on c-Ets-2 and MAPK signal pathway.
Hepatitis B X-interacting protein promotes cisplatin resistance and regulates CD147 via Sp1 in ovarian cancer.
Identification of Compounds Targeting Hepatitis B Virus Core Protein Dimerization Through a Split Luciferase Complementation Assay.
Multiple liver-specific factors bind to the hepatitis B virus core/pregenomic promoter: trans-activation and repression by CCAAT/enhancer binding protein.
Naturally occurring deletions/insertions in HBV core promoter tend to decrease in hepatitis B e antigen-positive chronic hepatitis B patients during antiviral therapy.
UU/UA dinucleotide frequency reduction in coding regions results in increased mRNA stability and protein expression.
Hepatitis C
A Cell-Based Assay for RNA Synthesis by the HCV Polymerase Reveals New Insights on Mechanism of Polymerase Inhibitors and Modulation by NS5A.
A new living cell-based assay system for monitoring genome-length hepatitis C virus RNA replication.
A novel luciferase and GFP dual reporter virus for rapid and convenient evaluation of hepatitis C virus replication.
Anti-Human Platelet Antigen-1a Immunoglobulin G Preparation Intended to Prevent Fetal and Neonatal Alloimmune Thrombocytopenia.
Characterization of the early steps of hepatitis C virus infection by using luciferase reporter viruses.
Development and Application of Hepatitis C Reporter Viruses with Genotype 1 to 7 Core-Nonstructural Protein 2 (NS2) Expressing Fluorescent Proteins or Luciferase in Modified JFH1 NS5A.
Development of a hepatitis C virus relapse model using genome-length hepatitis C virus ribonucleic acid-harboring cells possessing the interferon-alpha-resistance phenotype.
Development of a robust luciferase reporter 1b/2a hepatitis C virus (HCV) for characterization of early stage HCV life cycle inhibitors.
Different anti-HCV profiles of statins and their potential for combination therapy with interferon.
Efficient replication of a full-length hepatitis C virus genome, strain O, in cell culture, and development of a luciferase reporter system.
Expression of target genes by coinfection with replication-deficient viral vectors.
Heat Shock Protein A6, a Novel HSP70, Is Induced During Enterovirus A71 Infection to Facilitate Internal Ribosomal Entry Site-Mediated Translation.
Helper virus-independent trans-replication of hepatitis C virus-derived minigenome.
In vivo dynamics of reporter Flaviviridae viruses.
Inhibition of hepatitis C virus replication in vitro by xanthohumol, a natural product present in hops.
Inhibition of hepatitis E virus replication by proteasome inhibitor is nonspecific.
Intracellular cleavage of hepatitis C virus RNA and inhibition of viral protein translation by hammerhead ribozymes.
Isolation and characterization of hepatitis C virus resistant to a novel phenanthridinone derivative.
ODE-(S)-HPMPA IS A POTENT AND SELECTIVE INHIBITOR OF HEPATITIS C VIRUS REPLICATION IN GENOTYPE 1A, 1B AND 2A REPLICONS.
Potent and selective inhibition of hepatitis C virus replication by novel phenanthridinone derivatives.
Promotion of viral IRES-mediated translation under amino acid starvation.
Properties of hepatitis C virus minigenome containing mutated 5'UTR region and luciferase transgene.
Simultaneous quantitative measurement of luciferase reporter activity and cell number in two- and three-dimensional cultures of hepatitis C virus replicons.
Hepatitis D
A human liver cell line exhibits efficient translation of HCV RNAs produced by a recombinant adenovirus expressing T7 RNA polymerase.
Hepatitis E
Biological or pharmacological activation of protein kinase C alpha constrains hepatitis E virus replication.
Hepatoblastoma
A mutant of hepatitis B virus X protein (HBx Delta 127) enhances hepatoma cell migration via osteopontin involving 5-lipoxygenase.
Amplification and overexpression of the IGF2 regulator PLAG1 in hepatoblastoma.
Bioluminescence Measurement of Time-Dependent Dynamic Changes of CYP-Mediated Cytotoxicity in CYP-Expressing Luminescent HepG2 Cells.
Characterization of rat liver-specific methionine adenosyltransferase gene promoter. Role of distal upstream cis-acting elements in the regulation of the transcriptional activity.
cis-regulatory elements within the proximal promoter of the rat gene encoding corticosteroid-binding globulin.
Discovery of peroxisome proliferator-activated receptor ? (PPAR?) activators with a ligand-screening system using a human PPAR?-expressing cell line.
Highly efficient transactivation by the yeast Kluyveromyces lactis transcription factor LAC9 and its inhibition by the negative regulator GAL80 in mammalian cells.
Human N-acetylglucosaminyltransferase III gene is transcribed from multiple promoters.
In Vivo Bioluminescence Imaging of Murine Xenograft Cancer Models with a Red-shifted Thermostable Luciferase.
Positive and negative regulatory regions in promoters of human glutathione transferase alpha genes.
Regulation by glucagon (cAMP) and insulin of the promoter of the human phosphoenolpyruvate carboxykinase gene (cytosolic) in cultured rat hepatocytes and in human hepatoblastoma cells.
Transcriptional activity of the tandem repeat polymorphism in the 5'-flanking region of the human CYP2E1 gene.
[Inhibition of hepatitis C virus gene expression by antisense nucleotide in vitro]
Herpes Simplex
A tumor-specific gene therapy strategy targeting dysregulation of the VHL/HIF pathway in renal cell carcinomas.
Anti-tumor effects of engineered mesenchymal stem cells in colon cancer model.
Detection of herpes simplex virus by measurement of luciferase activity in an infected-cell lysate.
EBV replicon vector system enhances transgene expression in vivo: applications to cancer gene therapy.
Effects of an upstream DNA curvature on the strength of HSV thymidine kinase promoter.
Effects of Endogenous Proteins and microRNA Target Sequence in a Positive Feedback System.
Effects of the phenolic contents of Mauritian endemic plant extracts on promoter activities of antioxidant enzymes.
Evidence for transcriptional interference in a dual-luciferase reporter system.
Exploitation of herpesviral transactivation allows quantitative reporter gene-based assessment of virus entry and neutralization.
Expression of functional estrogen receptors and galanin messenger ribonucleic acid in immortalized luteinizing hormone-releasing hormone neurons: estrogenic control of galanin gene expression.
In vivo molecular imaging of murine embryonic stem cells delivered to a burn wound surface via Integra® scaffolding.
Lack of significant estrogenic or antiestrogenic activity of pyrethroid insecticides in three in vitro assays based on classic estrogen receptor alpha-mediated mechanisms.
Late temporal gene expression from the human cytomegalovirus pp28US (UL99) promoter when integrated into the host cell chromosome.
Midkine and cyclooxygenase-2 promoters are promising for adenoviral vector gene delivery of pancreatic carcinoma.
Midkine promoter-based adenoviral vector gene delivery for pediatric solid tumors.
Monitoring the efficacy of adoptively transferred prostate cancer-targeted human T lymphocytes with PET and bioluminescence imaging.
NF-kappa B regulates BCL3 transcription in T lymphocytes through an intronic enhancer.
Noninvasive imaging of cationic lipid-mediated delivery of optical and PET reporter genes in living mice.
Positive feedback system provides efficient and persistent transgene expression.
Regulation of function of the murine luteinizing hormone receptor promoter by cis- and trans-acting elements in mouse Leydig tumor cells.
Regulation of tyrosinase expression and activity in cultured human retinal pigment epithelial cells.
RNA-Seq investigations of human post-mortem trigeminal ganglia.
Serological diagnosis of human herpes simplex virus type 1 and 2 infections by luciferase immunoprecipitation system assay.
Serum decreases the size of Metafectene-and Genejammer-DNA complexes but does not affect significantly their transfection activity in SCCVII murine squamous cell carcinoma cells.
Targeted therapy with fatty acid synthase inhibitors in a human prostate carcinoma LNCaP/tk-luc-bearing animal model.
The effects of calcium channel blockers on nuclear factor kappa B activation in the mesangium cells.
Two-step transcriptional amplification-lipid-based nanoparticles using PSMA or midkine promoter for suicide gene therapy in prostate cancer.
Use of Epstein-Barr virus nuclear antigen-1 in targeted therapy of EBV-associated neoplasia.
Using a split luciferase assay (SLA) to measure the kinetics of cell-cell fusion mediated by herpes simplex virus glycoproteins.
HIV Infections
A novel dual luciferase assay for the simultaneous monitoring of HIV infection and cell viability.
A sensitive reporter cell line for HIV-1 tat activity, HIV-1 inhibitors, and T cell activation effects.
Activation of the human immunodeficiency virus long terminal repeat in THP-1 cells by a staphylococcal extracellular product.
Genome-Wide Characterization of Host Transcriptional and Epigenetic Alterations During HIV Infection of T Lymphocytes.
IL-27 posttranslationally regulates Y-box binding protein-1 to inhibit HIV-1 replication in human CD4+ T cells.
Repeated lipopolysaccharide (LPS) exposure inhibits HIV replication in primary human macrophages.
The impact of pregnancy on anti-HIV activity of cervicovaginal secretions.
Hyperglycemia
Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia.
Effects of plasmid DNA injection on cyclophosphamide-accelerated diabetes in NOD mice.
Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation.
Hyperinsulinemia enhances transcriptional activity of nuclear factor-kappaB induced by angiotensin II, hyperglycemia, and advanced glycosylation end products in vascular smooth muscle cells.
Hypersensitivity
A convenient and sensitive allergy test: IgE crosslinking-induced luciferase expression in cultured mast cells.
A novel strategy to modify adenovirus tropism and enhance transgene delivery to activated vascular endothelial cells in vitro and in vivo.
ABCC6 Expression Is Regulated by CCAAT/Enhancer-Binding Protein Activating a Primate-Specific Sequence Located in the First Intron of the Gene.
Association of the CCR3 gene polymorphism with aspirin exacerbated respiratory disease.
Cell-based Functional IgE Assays are Superior to Conventional Allergy Tests for Shrimp Allergy Diagnosis.
Cell-specific transcription of leukotriene C(4) synthase involves a Kruppel-like transcription factor and Sp1.
Cross-allergenicity of crustacean and the edible insect Gryllus bimaculatus in patients with shrimp allergy.
Different Results of IgE Binding- and Crosslinking-Based Allergy Tests Caused by Allergen Immobilization.
Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in transgenic mice.
Identification and characterization of mechanistically distinct inducers of gamma-globin transcription.
Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells.
MicroRNA-200a Targets Cannabinoid Receptor 1 and Serotonin Transporter to Increase Visceral Hyperalgesia in Diarrhea-predominant Irritable Bowel Syndrome Rats.
Hypertension
Deregulation of microRNA?31a?5p is involved in the development of primary hypertension by suppressing apoptosis of pulmonary artery smooth muscle cells via targeting TP53.
Molecular mechanism of miR-181b in heart disease due to pregnancy-induced hypertension syndrome.
Posttranscriptional control of BNP gene expression in angiotensin II-induced hypertension.
Reversal of renal lesions following interruption of nitric oxide synthesis inhibition in transgenic mice.
Role of miR-128 in hypertension-induced myocardial injury.
Hypertension, Pulmonary
The MicroRNA-328 Regulates Hypoxic Pulmonary Hypertension by Targeting at Insulin Growth Factor 1 Receptor and L-Type Calcium Channel-?1C.
Hyperthyroidism
Cloning of the cat TSH receptor and evidence against an autoimmune etiology of feline hyperthyroidism.
Hypopigmentation
Human amniotic stem cells-derived exosmal miR-181a-5p and miR-199a inhibit melanogenesis and promote melanosome degradation in skin hyperpigmentation, respectively.
Hypospadias
Screening of MAMLD1 mutations in 70 children with 46,XY DSD: identification and functional analysis of two new mutations.
Infarction, Middle Cerebral Artery
In vivo Tracking of Transplanted Bone Marrow-Derived Mesenchymal Stem Cells in a Murine Model of Stroke by Bioluminescence Imaging.
MicroRNA-9a-5p Alleviates Ischemia Injury After Focal Cerebral Ischemia of the Rat by Targeting ATG5-Mediated Autophagy.
Neurogenesis upregulation on the healthy hemisphere after stroke enhances compensation for age-dependent decrease of basal neurogenesis.
Infections
3-Hydroxyphthalic Anhydride-Modified Human Serum Albumin as a Microbicide Candidate Against HIV Type 1 Entry by Targeting Both Viral Envelope Glycoprotein gp120 and Cellular Receptor CD4.
A cell line that expresses a reporter gene in response to infection by Sindbis virus: a prototype for detection of positive strand RNA viruses.
A Four-Antigen Mixture for Rapid Assessment of Onchocerca volvulus Infection.
A Luciferase Gene Driven by an Alphaherpesviral Promoter Also Responds to Immediate Early Antigens of the Betaherpesvirus HCMV, Allowing Comparative Analyses of Different Human Herpesviruses in One Reporter Cell Line.
A luciferase immunoprecipitation systems assay enhances the sensitivity and specificity of diagnosis of Strongyloides stercoralis infection.
A luciferase reporter for gene expression studies and dynamic imaging of superficial Candida albicans infections.
A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection.
A luciferase-reporter gene-expressing T-cell line facilitates neutralization and drug-sensitivity assays that use either R5 or X4 strains of human immunodeficiency virus type 1.
A method to measure an indicator of viraemia in Atlantic salmon using a reporter cell line.
A mouse model for studying the clearance of hepatitis B virus in vivo using a luciferase reporter.
A multifunctional, synthetic Gaussia princeps luciferase reporter for live imaging of Candida albicans infections.
A new indicator cell line established to monitor bovine foamy virus infection.
A novel assay for ADCC against HIV-1 or SIV-infected cells reveals incomplete overlap with antibodies measured by neutralization and binding assays.
A Novel Oncolytic Chimeric Orthopoxvirus Encoding Luciferase Enables Real-Time View of Colorectal Cancer Cell Infection.
A panel of Trypanosoma brucei strains tagged with blue and red-shifted luciferases for bioluminescent imaging in murine infection models.
A quantitative and highly sensitive luciferase-based assay for bacterial toxins that inhibit protein synthesis.
A quantitative assay for measuring of bovine immunodeficiency virus using a luciferase-based indicator cell line.
A sensitive and versatile bioluminescence bioassay for HIV type 1 based on adenoviral vectors.
A sensitive model system for in vivo monitoring of baculovirus gene expression in single infected insect cells.
A sensitive reporter cell line for HIV-1 tat activity, HIV-1 inhibitors, and T cell activation effects.
A simple, lanthanide-based method to enhance the transduction efficiency of adenovirus vectors.
A stable luciferase reporter plasmid for in vivo imaging in murine models of Staphylococcus aureus infections.
A study of varicella zoster virus glycoprotein C regulatory region response to viral activators in vitro.
A surrogate assay for measuring Coxsackievirus A6 neutralizing antibodies.
A synthetic vaccinia virus promoter with enhanced early and late activity.
A three-dimensional assay for measurement of viral-induced oncolysis.
A transgenic Plasmodium falciparum NF54 strain that expresses GFP-luciferase throughout the parasite life cycle.
Activation of caspase-3 during Chlamydia trachomatis-induced apoptosis at a late stage.
Activation of telomerase by human cytomegalovirus.
Activity in vivo of anti-Trypanosoma cruzi compounds selected from a high throughput screening.
Adenovirus hexon modifications influence in vitro properties of pseudotyped human adenovirus type 5 vectors.
Adenoviruses with an RGD-4C modification of the fiber knob elicit a neutralizing antibody response but continue to allow enhanced gene delivery.
Alveolar macrophages inhibit retrovirus-mediated gene transfer to airway epithelia.
Amplification, expression, and packaging of a foreign gene by giardiavirus in Giardia lamblia.
Amplified Muc1-specific gene expression in colon cancer cells utilizing a binary system in adenoviral vectors.
An adenoviral vector-based system to study neuronal gene expression: analysis of the rat tyrosine hydroxylase promoter in cultured neurons.
Analysis of adaptive mutations in Kunjin virus replicon RNA reveals a novel role for the flavivirus nonstructural protein NS2A in inhibition of beta interferon promoter-driven transcription.
Analysis of cysteine protease inhibitor gene (BmCPI) promoter activity in silkworms using bac-to-bac baculovirus systems.
Analysis of Yersinia enterocolitica invasin expression in vitro and in vivo using a novel luxCDABE reporter system.
Antibody profiling Borrelia burgdorferi infection in horses.
Antibody profiling by Luciferase Immunoprecipitation Systems (LIPS).
Antibody to the filarial antigen Wb123 reflects reduced transmission and decreased exposure in children born following single mass drug administration (MDA).
Antibody-dependent enhancement of adeno-associated virus infection of human monocytic cell lines.
Assessment of immunity to mycobacterial infection with luciferase reporter constructs.
Assessment of in vitro immunity to Mycobacterium tuberculosis in a human peripheral blood infection model using a luciferase reporter construct of M. tuberculosis H37Rv.
Astrocytes Resist HIV-1 Fusion but Engulf Infected Macrophage Material.
Augmented adenovirus transduction of murine T lymphocytes utilizing a bi-specific protein targeting murine interleukin 2 receptor.
Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains.
Bacterial luciferase gene cassette as a real-time bioreporter for infection model and drug evaluation.
Bacterial luciferase produced with rapid-screening baculovirus vectors is a sensitive reporter for infection of insect cells and larvae.
Baculovirus mediated high-level expression of luciferase in silkworm cells and larvae.
Biological or pharmacological activation of protein kinase C alpha constrains hepatitis E virus replication.
Bioluminescence imaging of Chlamydia muridarum ascending infection in mice.
Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains.
Bioluminescent fungi for real-time monitoring of fungal infections.
Bioluminescent Leishmania expressing luciferase for rapid and high throughput screening of drugs acting on amastigote-harbouring macrophages and for quantitative real-time monitoring of parasitism features in living mice.
Bioluminescent:Fluorescent Trypanosoma cruzi Reporter Strains as Tools for Exploring Chagas Disease Pathogenesis and Drug Activity.
Blocking of the alpha interferon-induced Jak-Stat signaling pathway by Japanese encephalitis virus infection.
Buprenorphine Increases HIV-1 Infection In Vitro but Does Not Reactivate HIV-1 from Latency.
c-SRC protein tyrosine kinase regulates early HIV-1 infection post-entry.
Cascade regulation of vaccinia virus gene expression is modulated by multistage promoters.
Cationic polypeptides contribute to the anti-HIV-1 activity of human seminal plasma.
Cauliflower mosaic virus, a compatible pathogen of Arabidopsis, engages three distinct defense-signaling pathways and activates rapid systemic generation of reactive oxygen species.
CD4/CXCR4-independent infection of human astrocytes by a T-tropic strain of HIV-1.
CD40-Mediated induction of CD4 and CXCR4 on B lymphocytes correlates with restricted susceptibility to human immunodeficiency virus type 1 infection: potential role of B lymphocytes as a viral reservoir.
Cell type-specific mechanisms of interleukin-8 induction by dengue virus and differential response to drug treatment.
Cell-free HIV type 1 infection is restricted in the human trophoblast choriocarcinoma BeWo cell line, even with expression of CD4, CXCR4 and CCR5.
Cetyltriethylammonium bromide stimulating transcription of Bombyx mori nucleopolyhedrovirus gp64 gene promoter mediated by viral factors.
cGMP stimulation of cystic fibrosis transmembrane conductance regulator Cl- channels co-expressed with cGMP-dependent protein kinase type II but not type Ibeta.
Characterization of cell-surface determinants important for baculovirus infection.
Characterization of Monkeypox virus infection in African rope squirrels (Funisciurus sp.).
Characterization of temperate phage Che12 and construction of a new tool for diagnosis of tuberculosis.
Characterization of the functional properties of env genes from long-term survivors of human immunodeficiency virus type 1 infection.
Comparative evaluation of survivin, midkine and CXCR4 promoters for transcriptional targeting of glioma gene therapy.
Comparative study of murid gammaherpesvirus 4 infection in mice and in a natural host, bank voles.
Comparison of vRNA and cRNA based reporters for detection of influenza replication.
Constitutive activation of the transcription factor NF-kappaB results in impaired borna disease virus replication.
Construction and identification of the adenoviral vector with dual reporter gene for multimodality molecular imaging.
Coreceptor/chemokine receptor expression on human hematopoietic cells: biological implications for human immunodeficiency virus-type 1 infection.
Culture at high density improves the ability of human macrophages to control mycobacterial growth.
Decreased expression of A-kinase anchoring protein 150 in GT1 neurons decreases neuron excitability and frequency of intrinsic gonadotropin-releasing hormone pulses.
Dehydroxymethylepoxyquinomicin selectively ablates T-CAEBV cells.
Deletion of IGF-I receptor (IGF-IR) in primary osteoblasts reduces GH-induced STAT5 signaling.
Demonstration of the specificity of poliovirus encapsidation using a novel replicon which encodes enzymatically active firefly luciferase.
Detection of herpes simplex virus by measurement of luciferase activity in an infected-cell lysate.
Detection, characterization and regulation of antisense transcripts in HIV-1.
Development and evaluation of a FACS-based medium-throughput assay for HCV entry inhibitors.
Development of a novel dengue-1 virus replicon system expressing secretory Gaussia luciferase for analysis of viral replication and discovery of antiviral drugs.
Development of a robust luciferase reporter 1b/2a hepatitis C virus (HCV) for characterization of early stage HCV life cycle inhibitors.
Development of a simple, rapid, sensitive, high-throughput luciferase reporter based microneutralization test for measurement of virus neutralizing antibodies following Respiratory Syncytial Virus vaccination and infection.
Differential response of the Senegalese sole (Solea senegalensis) Mx promoter to viral infections in two salmonid cell lines.
Disruption of bbe02 by Insertion of a Luciferase Gene Increases Transformation Efficiency of Borrelia burgdorferi and Allows Live Imaging in Lyme Disease Susceptible C3H Mice.
Downregulation of miR-155-5p facilitates enterovirus 71 replication through suppression of type I IFN response by targeting FOXO3/IRF7 pathway.
Early induction of the Arabidopsis GSTF8 promoter by specific strains of the fungal pathogen Rhizoctonia solani.
Effect of adeno-associated virus-specific immunoglobulin G in human amniotic fluid on gene transfer.
Effective infection, apoptotic cell killing and gene transfer of human hepatoma cells but not primary hepatocytes by parvovirus H1 and derived vectors.
Effects of infection rate and selection pressure on gene expression from an internal promoter of a double gene retroviral vector.
Effects of post-challenge administration of ST-246 on dissemination of IHD-J-Luc vaccinia virus in normal and in immune deficient mice reconstituted with T cells.
Effects of the Ad5 upstream E1 region and gene products on heterologous promoters.
Efficient and sustained transgene expression in mature rat oligodendrocytes in primary culture.
Efficient lentiviral vectors for short hairpin RNA delivery into human cells.
EGF-induced activation of Akt results in mTOR- dependent p70S6 kinase phosphorylation and inhibition of HC11 cell lactogenic differentiation.
Ehrlichia chaffeensis TRP32 is a Nucleomodulin that Directly Regulates Expression of Host Genes Governing Differentiation and Proliferation.
Emodin Inhibition of Influenza A Virus Replication and Influenza Viral Pneumonia via the Nrf2, TLR4, p38/JNK and NF-kappaB Pathways.
Encapsidation of a recombinant LuIII parvovirus genome by H1 virus and the fibrotropic or lymphotropic strains of minute virus of mice.
Encephalitozoon microsporidia modulates p53-mediated apoptosis in infected cells.
Enhancement of cauliflower mosaic virus 35S promoter in insect cells infected with baculovirus.
Enterohemorrhagic, but not enteropathogenic, Escherichia coli infection of epithelial cells disrupts signalling responses to tumour necrosis factor-alpha.
ENTRY SITES OF VENEZUELAN AND WESTERN EQUINE ENCEPHALITIS VIRUSES IN THE MOUSE CENTRAL NERVOUS SYSTEM FOLLOWING PERIPHERAL INFECTION.
Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models.
Establishment and characterization of a Madin-Darby canine kidney reporter cell line for influenza A virus assays.
Establishment of a cell-based assay for screening of compounds inhibiting very early events in the cytomegalovirus replication cycle and characterization of a compound identified using the assay.
Establishment of a neutralization test involving reporter gene-expressing virus-like particles of tick-borne encephalitis virus.
Establishment of an indicator cell system for hepatitis C virus.
Establishment of cell-based reporter system for diagnosis of poxvirus infection.
Evaluating aziridinyl nitrobenzamide compounds as leishmanicidal prodrugs.
Evaluation of polycaprolactone matrices for sustained vaginal delivery of nevirapine in the prevention of heterosexual HIV transmission.
Evaluation of the inflammatory potential of implant materials in a mouse model by bioluminescent imaging of intravenously injected bone marrow cells.
Evaluation of the Synthesis of Sialic Acid-PAMAM Glycodendrimers without the Use of Sugar Protecting Groups, and the Anti-HIV-1 Properties of These Compounds.
Evaluation of tumor-specific promoter activities in melanoma.
Ex vivo promoter analysis of antiviral heat shock cognate 70B gene in Anopheles gambiae.
Examining human T-lymphotropic virus type 1 infection and replication by cell-free infection with recombinant virus vectors.
Exploitation of herpesviral transactivation allows quantitative reporter gene-based assessment of virus entry and neutralization.
Expression of highly controllable genes in insect cells using a modified tetracycline-regulated gene expression system.
Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells.
Expression pattern and transcriptional regulatory mechanism of noxa gene in grass carp (Ctenopharyngodon idella).
Extracellular histones identified in crocodile blood inhibit in-vitro HIV-1 infection.
Facilitated DNA transfer to rat submandibular gland in vivo and GRP-Ca gene regulation.
Firefly luciferase as a marker for herpesvirus (pseudorabies virus) replication in vitro and in vivo.
Foreign Gene Transfer to Cardiomyocyte Using a Replication-Defective Recombinant Coxsackievirus B3 without Cytotoxicity.
Fosfomycin suppresses chemokine induction in airway epithelial cells infected with the respiratory syncytial virus.
Frequency of intrinsic pulsatile gonadotropin-releasing hormone secretion is regulated by the expression of cyclic nucleotide-gated channels in GT1 cells.
Functional analysis of 3'UTR polymorphisms in the caprine SLC11A1 gene and its association with the Mycobacterium avium subsp. paratuberculosis infection.
Functional analysis of RNAi suppressor P19 on improving baculovirus yield and transgene expression in Sf9 cells
Functional analysis of RNAi suppressor P19 on improving baculovirus yield and transgene expression in Sf9 cells.
Functional analysis of the interferon-stimulated response element of porcine circovirus type 2 and its role during viral replication in vitro and in vivo.
Functional miR-142a-3p Induces Apoptosis and Macrophage Polarization by Targeting tnfaip2 and glut3 in Grass Carp (Ctenopharyngodon idella).
Gene silencing from plant DNA carried by a Geminivirus.
Generation and characterization of luciferase-secreting, single-round infectious DENV-2 reporter for functional antibody assays.
Generation of a reporter cell line for detection of infectious varicella-zoster virus and its application to antiviral studies.
Genetic modification of the vessel wall. Comparison of surgical and catheter-based techniques for delivery of recombinant adenovirus.
Genotypic and phenotypic characterization of long terminal repeat sequences from long-term survivors of human immunodeficiency virus type 1 infection.
gga-miR-451 Negatively Regulates Mycoplasma gallisepticum (HS Strain)-Induced Inflammatory Cytokine Production via Targeting YWHAZ.
Glutaredoxin regulates nuclear factor kappa-B and intercellular adhesion molecule in Müller cells: model of diabetic retinopathy.
Helicobacter pylori-induced cell death is counteracted by NF-?B-mediated transcription of DARPP-32.
Helicobacter pylori-induced posttranscriptional regulation of H-K-ATPase ?-subunit gene expression by miRNA.
Hepatocyte-specific gene expression by baculovirus pseudotyped with vesicular stomatitis virus envelope glycoprotein.
Herpes simplex virus 1 induced LOX-1 expression in an endothelial cell line, ECV 304.
Herpes simplex virus 1 targets the murine olfactory neuroepithelium for host entry.
Herpes simplex virus 1 tropism for human sensory ganglion neurons in the severe combined immunodeficiency mouse model of neuropathogenesis.
Heterologous promoter recognition leading to high-level expression of cloned foreign genes in Bombyx mori cell lines and larvae.
Host miR-26a suppresses replication of porcine reproductive and respiratory syndrome virus by upregulating type I interferons.
Host-derived ICAM-1 glycoproteins incorporated on human immunodeficiency virus type 1 are biologically active and enhance viral infectivity.
HSV-1 infected cell proteins influence tetracycline-regulated transgene expression.
Human herpesvirus 7 induces the down-regulation of CD4 antigen in lymphoid T cells without affecting p56lck levels.
Human immunodeficiency virus type 1 enters brain microvascular endothelia by macropinocytosis dependent on lipid rafts and the mitogen-activated protein kinase signaling pathway.
Human immunodeficiency virus type 1 uses lipid raft-colocalized CD4 and chemokine receptors for productive entry into CD4(+) T cells.
Human T-Cell Leukemia Virus Type 1 (HTLV-1) bZIP Factor Upregulates the Expression of ICAM-1 To Facilitate HTLV-1 Infection.
Human T-cell leukemia virus type-I (HTLV-I) tax is not the only one factor to enhance human immunodeficiency virus type-I (HIV-1) infection in culture-supernatants.
Human trophoblasts confer resistance to viruses implicated in perinatal infection.
Identification of a replication-competent pathogenic human immunodeficiency virus type 1 with a duplication in the TCF-1alpha region but lacking NF-kappaB binding sites.
Identification of novel human adenovirus candidates using the coxsackievirus and adenovirus receptor for cell entry.
Identification of Slug and Sox7 as transcriptional repressors binding to the Hepatitis B Virus Core Promoter.
Identification of the IFN-? response in H3N2 canine influenza virus infection.
Idiopathic Hypersomnia Patients Revealed Longer Circadian Period Length in Peripheral Skin Fibroblasts.
IFNGR1 signaling is associated with adverse pregnancy outcomes during infection with malaria parasites.
Imaging luciferase-expressing viruses.
Imaging of bioluminescent Klebsiella pneumoniae induced pulmonary infection in an immunosuppressed mouse model.
Impact of inhibitors and L2 antibodies upon the infectivity of diverse alpha and beta human papillomavirus types.
Improved adenovirus vectors for infection of cardiovascular tissues.
Improved production of recombinant AAV by transient transfection of NB324K cells using electroporation.
In vitro activities of candidate microbicides against cell-associated HIV.
In vivo analysis of Yersinia enterocolitica infection using luxCDABE.
In Vivo Bacterial Imaging Using Bioluminescence.
In vivo Bioluminescence-Based Monitoring of Liver Metastases from Colorectal Cancer: An Experimental Model.
In Vivo Bioluminescent Imaging of Yersinia ruckeri Pathogenesis in Fish.
In vivo imaging of bioluminescent Pseudomonas aeruginosa in an acute murine airway infection model.
In vivo imaging of murid herpesvirus-4 infection.
In vivo imaging systems (IVIS) detection of a neuro-invasive encephalitic virus.
In Vivo Live Imaging of Oncolytic Mammalian Orthoreovirus Expressing NanoLuc Luciferase in Tumor Xenograft Mice.
Increased Viral Dissemination in the Brain and Lethality in MCMV-Infected, Dicer-Deficient Neonates.
Induction of interleukins IL-6 and IL-8 by siRNA.
Infection by bacterial pathogens expressing type III secretion decreases luciferase activity: ramifications for reporter gene studies.
Infection of cultured embryo cells of the pacific oyster, Crassostrea gigas, by pantropic retroviral vectors.
Infectious Bronchitis Virus as a Vector for the Expression of Heterologous Genes.
Inhibition of gene expression from the human c-erbB gene promoter by a retroviral vector expressing anti-gene RNA.
Inhibition of HIV early replication by the p53 and its downstream gene p21.
Inhibition of HIV infectivity by a natural human isolate of Lactobacillus jensenii engineered to express functional two-domain CD4.
Inhibition of HIV-1 replication in human monocyte-derived macrophages by parasite Trypanosoma cruzi.
Inhibitory activity of limonoids from Khaya grandifoliola C.DC (Meliaceae) against hepatitis C virus infection in vitro.
Insights into the Host Range, Genetic Diversity, and Geographical Distribution of Jingmenviruses.
Integrative analysis of lncRNA-miRNA-mRNA-associated competing endogenous RNA regulatory network involved in EV71 infection.
Interferon induction and suppression in swine testicle cells by porcine parvovirus and its proteins.
Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice.
International network for comparison of HIV neutralization assays: the NeutNet report.
Intraductal Injection of LPS as a Mouse Model of Mastitis: Signaling Visualized via an NF-?B Reporter Transgenic.
Khaya grandifoliola C.DC: a potential source of active ingredients against hepatitis C virus in vitro.
L5 luciferase reporter mycobacteriophages: a sensitive tool for the detection and assay of live mycobacteria.
LabKey Server NAb: a tool for analyzing, visualizing and sharing results from neutralizing antibody assays.
Late temporal gene expression from the human cytomegalovirus pp28US (UL99) promoter when integrated into the host cell chromosome.
Lentiviral vector-derived shRNAs confer enhanced suppression of Semliki forest virus replication in BHK-21 cells compared to shRNAs expressed from plasmids.
Lethal Hemorrhagic Disease and Clinical Illness Associated with Elephant Endotheliotropic Herpesvirus 1 Are Caused by Primary Infection: Implications for the Detection of Diagnostic Proteins.
Linking bacteriophage infection to quorum sensing signalling and bioluminescent bioreporter monitoring for direct detection of bacterial agents.
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
Local delivery of the viral interleukin-10 gene suppresses tissue inflammation in murine Pneumocystis carinii infection.
Long-term expression after infection by the hybrid vector AdLTR-luc is from integrated transgene.
Luciferase-tagged wild-type and tropism-deficient mouse cytomegaloviruses reveal early dynamics of host colonization following peripheral challenge.
LuSIV cells: a reporter cell line for the detection and quantitation of a single cycle of HIV and SIV replication.
MafF Is an Antiviral Host Factor That Suppresses Transcription from Hepatitis B Virus Core Promoter.
Mature and functional viral miRNAs transcribed from novel RNA polymerase III promoters.
Measuring HIV neutralization in a luciferase reporter gene assay.
Methionyl-tRNA synthetase inhibitor has potent in vivo activity in a novel Giardia lamblia luciferase murine infection model.
Methylation of secreted frizzled-related protein 1 (SFRP1) promoter downregulates Wnt/?-catenin activity in keloids.
Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates.
MicroRNA-23b inhibits enterovirus 71 replication through downregulation of EV71 VPl protein.
MiR-10a-5p-Mediated Syndecan 1 Suppression Restricts Porcine Hemagglutinating Encephalomyelitis Virus Replication.
Mir-302c mediates influenza A virus-induced IFN? expression by targeting NF-?B inducing kinase.
Mitogen-activated protein kinases and NFkappaB are involved in SP-A-enhanced responses of macrophages to mycobacteria.
Mode of transgene expression after fusion to early or late viral genes of a conditionally replicating adenovirus via an optimized internal ribosome entry site in vitro and in vivo.
Murine Leukemia Virus (MLV)-based Coronavirus Spike-pseudotyped Particle Production and Infection.
Murine skin and vaginal mucosa are similarly susceptible to infection by pseudovirions of different papillomavirus classifications and species.
Mycobacteriophage L5 infection of Mycobacterium bovis BCG: implications for phage genetics in the slow-growing mycobacteria.
Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation.
Neuron-restrictive silencer elements mediate neuron specificity of adenoviral gene expression.
Neutralizing activity to SARS-CoV-2 of convalescent and control plasma used in a randomized controlled trial.
NF-?B Activity in Perinatal Brain During Infectious and Hypoxic-Ischemic Insults Revealed by a Reporter Mouse.
NFAT4 is required for JC virus infection of glial cells.
NFkappaB and Sp1 elements are necessary for maximal transcription of toll-like receptor 2 induced by Mycobacterium avium.
Noninvasive bioluminescence imaging of herpes simplex virus type 1 infection and therapy in living mice.
Notch1 signaling regulates the proliferation and self-renewal of human dental follicle cells by modulating the G1/S phase transition and telomerase activity.
Nuclear factor kappa B-dependent gene transcription in cholecystokinin- and tumor necrosis factor-alpha-stimulated isolated acinar cells is regulated by p38 mitogen-activated protein kinase.
Outcome of Antiviral Immunity in the Liver Is Shaped by the Level of Antigen Expressed in Infected Hepatocytes.
Over expression of bmo-miR-2819 suppresses BmNPV replication by regulating the BmNPV ie-1 gene in Bombyx mori.
Parvoviruses are inefficient in inducing interferon-beta, tumor necrosis factor-alpha, or interleukin-6 in mammalian cells.
Pasteurella multocida toxin-induced activation of RhoA is mediated via two families of G{alpha} proteins, G{alpha}q and G{alpha}12/13.
Peptide T inhibits HIV-1 infection mediated by the chemokine receptor-5 (CCR5).
PGJ2 antagonizes NF-kappaB-induced HIV-1 LTR activation in colonic epithelial cells.
Pharmacological expression in rat hepatocytes of a gene transferred by an adenovirus vector enabled by a chimeric promoter containing multiple cyclic adenosine monophosphate response elements.
Phosphorothioate hammerhead ribozymes targeting a conserved sequence in the V3 loop region inhibit HIV-1 entry.
Plasmid-based generation of recombinant coxsackievirus B3 particles carrying capsid gene replacement replicons.
Porcine reproductive and respiratory syndrome virus (PRRSV) infection activates chemokine RANTES in MARC-145 cells.
Porcine transmissible gastroenteritis virus inhibits NF-?B activity via nonstructural protein 3 to evade host immune system.
Porcine transmissible gastroenteritis virus nonstructural protein 2 contributes to inflammation via NF-?B activation.
Post-parturient shedding of Listeria monocytogenes in breast milk of infected mice. [corrected].
Postcoital bioavailability and antiviral activity of 0.5% PRO 2000 gel: implications for future microbicide clinical trials.
Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting.
Prophylactic immunization with human papillomavirus vaccines induces oral immunity in mice.
Protease inhibitors elicit anti-inflammatory effects in CF mice with Pseudomonas aeruginosa acute lung infection.
Pseudomonas aeruginosa infection destroys the barrier function of lung epithelium and enhances polyplex-mediated transfection.
Rapid assessment of drug susceptibilities of Mycobacterium tuberculosis by means of luciferase reporter phages.
Rapid film-based determination of antibiotic susceptibilities of Mycobacterium tuberculosis strains by using a luciferase reporter phage and the Bronx Box.
Rapid, novel, specific, high-throughput assay for diagnosis of Loa loa infection.
Recombinant adeno-associated virus for the generation of autologous, gene-modified tumor vaccines: evidence for a high transduction efficiency into primary epithelial cancer cells.
Recombinant Hepatitis E Viruses Harboring Tags in the ORF1 Protein.
Recombinant Pseudorabies Virus (PRV) Expressing Firefly Luciferase Effectively Screened for CRISPR/Cas9 Single Guide RNAs and Antiviral Compounds.
Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi.
Red-Shifted Firefly Luciferase Optimized for Candida albicans In vivo Bioluminescence Imaging.
Reevaluation of confirmatory tests for human T-cell leukemia virus Type 1 using a luciferase immunoprecipitation system in blood donors.
Regulation and rate limiting mechanisms of Ca2+ ATPase (SERCA2) expression in cardiac myocytes.
Replacement of the V3 region of gp120 with SDF-1 preserves the infectivity of T-cell line-tropic human immunodeficiency virus type 1.
Replication-Competent ?NS1 Influenza A Viruses Expressing Reporter Genes.
Replication-dependent transgene expression from a conditionally replicating adenovirus via alternative splicing to a heterologous splice-acceptor site.
Reporter gene expression in fish following cutaneous infection with pantropic retroviral vectors.
Reporter genes for real-time in vive monitoring of Ochrobactrum anthropi infection.
Restoration of RNA helicase DDX5 suppresses hepatitis B virus (HBV) biosynthesis and Wnt signaling in HBV-related hepatocellular carcinoma.
Rodents Versus Pig Model for Assessing the Performance of Serotype Chimeric Ad5/3 Oncolytic Adenoviruses.
Role of Ras-related Nuclear Protein/Polypyrimidine Tract Binding Protein in Facilitating the Replication of Hepatitis C Virus.
Rotavirus infection induces the unfolded protein response of the cell and controls it through the nonstructural protein NSP3.
Screening Inhibitors of P. berghei Blood Stages Using Bioluminescent Reporter Parasites.
Screening of small-molecule compounds as inhibitors of HCV entry.
Selective targeting of adenovirus to alphavbeta3 integrins, VEGFR2 and Tie2 endothelial receptors by angio-adenobodies.
Sendai virus C proteins must interact directly with cellular components to interfere with interferon action.
Serological diagnosis of human herpes simplex virus type 1 and 2 infections by luciferase immunoprecipitation system assay.
Seroprevalence of toxoplasmosis among reproductive-aged women in Myanmar and evaluation of luciferase immunoprecipitation system assay.
Singapore grouper iridovirus (SGIV) encoded SGIV-miR-13 attenuates viral infection via modulating major capsid protein expression.
Single cell detection of latent cytomegalovirus reactivation in host tissue.
Single-Stranded Oligonucleotide-Mediated Inhibition of Respiratory Syncytial Virus Infection.
Small RNA analysis provides new insights into cytoplasmic incompatibility in Drosophila melanogaster induced by Wolbachia.
Spatiotemporally Skewed Activation of Programmed Cell Death Receptor 1-Positive T Cells after Epstein-Barr Virus Infection and Tumor Development in Long-Term Fully Humanized Mice.
Specific NFkappaB subunit activation and kinetics of cytokine induction in adenoviral keratitis.
Study of Andes virus entry and neutralization using a pseudovirion system.
Subcapsular sinus macrophages limit dissemination of West Nile virus particles after inoculation but are not essential for the development of West Nile virus-specific T cell responses.
Successful biolistic transformation of mouse pancreatic islets while preserving cellular function.
Synthetic Neutralizing Peptides Inhibit the Host Cell Binding of Spike Protein and Block Infection of SARS-CoV-2.
T7 infection-dependent selective expression of cloned genes in P1-lysogenic Escherichia coli.
Targeted gene delivery by tropism-modified adenoviral vectors.
Targeting adenovirus gene delivery to activated tumour-associated vasculature via endothelial selectins.
The B-oligomer of pertussis toxin inhibits human immunodeficiency virus type 1 replication at multiple stages.
The cyclo-oxygenase 2 promoter is induced in nontarget cells following adenovirus infection, but an AU-rich 3'-untranslated region destabilization element can increase specificity.
The Cytomegalovirus Tegument Protein UL35 Antagonizes Pattern Recognition Receptor-Mediated Type I IFN Transcription.
The ecdysteroid UDP-glucosyltransferase gene promoter from Autographa californica multicapsid nucleopolyhedrovirus.
The effect of promoter strength in adenoviral vectors in hyperplastic synovium.
The Effects of Statistical Multiplicity of Infection on Virus Quantification and Infectivity Assays.
The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication.
The organotypic multicellular spheroid is a relevant three-dimensional model to study adenovirus replication and penetration in human tumors in vitro.
The potential of 5-fluorocytosine/cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model.
The serological evidence in humans supports a negligible risk of zoonotic infection from porcine circovirus type 2.
The vaccinia virus fusion inhibitor proteins SPI-3 (K2) and HA (A56) expressed by infected cells reduce the entry of superinfecting virus.
The Vaginal Acquisition and Dissemination of HIV-1 Infection in a Novel Transgenic Mouse Model Is Facilitated by Coinfection with Herpes Simplex Virus 2 and Is Inhibited by Microbicide Treatment.
Three model systems measure oxidation/nitration damage caused by peroxynitrite.
TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death.
trans-encapsidation of a poliovirus replicon by different picornavirus capsid proteins.
Transactivation of inducible nitric oxide synthase gene by Kruppel-like factor 6 regulates apoptosis during influenza A virus infection.
Transcriptional regulation of BK virus by nuclear factor of activated T cells.
Transcriptional Regulation of gga-miR-451 by AhR:Arnt in Mycoplasma gallisepticum (HS Strain) Infection.
Transduction of foreign regulatory sequences by a replication-defective herpes simplex virus type 1: the rat neuron-specific enolase promoter.
Transfer of activation-dependent gene expression into T cell lines by recombinant adeno-associated virus.
Transgenic Silkworm of Anti-NPV Ribozyme.
Trefoil factor 1 expression suppresses Helicobacter pylori-induced inflammation in gastric carcinogenesis.
Trypanocidal activity of aziridinyl nitrobenzamide prodrugs.
Tumour necrosis factor-alpha stimulates HIV-1 replication in single-cycle infection of human term placental villi fragments in a time, viral dose and envelope dependent manner.
Unique susceptibility of a human lung carcinoid tumor cell line to infection with BK virus.
Upon intranasal vesicular stomatitis virus infection, astrocytes in the olfactory bulb are important interferon Beta producers that protect from lethal encephalitis.
Use of luminescent Leptospira interrogans for enumeration in biological assays.
Using luciferase to image bacterial infections in mice.
Validation of PhageDxTM  Cronobacter Assay for the Identification of Cronobacter spp. in Powdered Infant Formula: AOAC Performance Tested MethodSM 051803.
Validation of PhageDx™ Salmonella Assay in Raw Ground Turkey and Powdered Infant Formula: AOAC Performance Tested MethodSM 121904.
Validation of the PhageDx™ Listeria Assay for Detection of Listeria Spp. on Stainless Steel and Ceramic Environmental Surfaces AOAC Performance Tested MethodSM 102005.
Video imaging of firefly luciferase activity to identify and monitor herpesvirus infection in cell culture.
Visualizing fungal infections in living mice using bioluminescent pathogenic Candida albicans strains transformed with the firefly luciferase gene.
VP8, the major tegument protein of bovine herpesvirus-1, interacts with cellular STAT1 and inhibits interferon-? signaling.
VPAC1 is a cellular neuroendocrine receptor expressed on T cells that actively facilitates productive HIV-1 infection.
Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes.
Zebrafish as a Model for the Study of Host-Virus Interactions.
[Development and Identification of the Recombinant Lentivirus Co-expressing HCV Structural Protein and Secreted Gaussia Luciferase (Gluc)].
[Enhanced transduction efficiency of adeno-associated virus on cancer cells with the help of low dose adenovirus]
[Helicobacter pylori cytotoxin associated protein CagA regulates gastrin gene promoter activity].
[Mechanism Underlying Increased Expression of a Member of the Serine/Threonine Kinase Family (Citron kinase) Induced by HIV-1 Infection].
[Refined adenoviral transduction for controlled gene transfer into human adult mesenchymal stem cells]
[Regulating effect of ORF128 on NF-?B signaling pathway of HEK293T cells and its mechanism].
Infertility
Overexpression of MicroRNA-10a in Germ Cells Causes Male Infertility by Targeting Rad51 in Mouse and Human.
Inflammatory Bowel Diseases
Genomics, transcriptomics, proteomics, and numbers.
Tracing the dynamic expression of the Nf?b2 gene during inflammatory processes by in vivo bioluminescence imaging in transgenic mice.
Inflammatory Breast Neoplasms
Evaluation of a CXCR4 antagonist in a xenograft mouse model of inflammatory breast cancer.
Influenza in Birds
A dual reporter gene based system to quantitate the cell fusion of avian influenza virus H5N1.
Analysis of oseltamivir resistance substitutions in influenza virus glycoprotein neuraminidase using a lentivirus-based surrogate assay system.
Characterization of recombinant raccoonpox vaccine vectors in chickens.
Influenza, Human
A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection.
A Novel Fluorescent and Bioluminescent Bireporter Influenza A Virus To Evaluate Viral Infections.
Analysis of oseltamivir resistance substitutions in influenza virus glycoprotein neuraminidase using a lentivirus-based surrogate assay system.
Biophysical characterization of sites of host adaptive mutation in the influenza A virus RNA polymerase PB2 RNA-binding domain.
Comparison of vRNA and cRNA based reporters for detection of influenza replication.
DMO-CAP inhibits influenza virus replication by activating heme oxygenase-1-mediated IFN response.
DNA as Tunable Adaptor for siRNA Polyplex Stabilization and Functionalization.
Elucidating the Interactions between Influenza Virus Polymerase and Host Factor ANP32A.
Epidemiological and Serological Investigation into the Role of Gestational Maternal Influenza Virus Infection and Autism Spectrum Disorders.
Establishment and characterization of a Madin-Darby canine kidney reporter cell line for influenza A virus assays.
Establishment of a Replicon Reporter of the Emerging Tick-Borne Bourbon Virus and Use It for Evaluation of Antivirals.
ICAM-1 regulates the survival of influenza virus in lung epithelial cells during the early stages of infection.
Identification of novel virus inhibitors by influenza A virus specific reporter cell based screening.
Identification of small molecules that interfere with H1N1 influenza A viral replication.
In vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies.
Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle.
Inhibition of influenza virus RNA (PB2 mRNA) expression by a modified DNA enzyme.
Mechanism of action of the suppression of influenza virus replication by Ko-Ken Tang through inhibition of the phosphatidylinositol 3-kinase/Akt signaling pathway and viral RNP nuclear export.
MicroRNA 34a contributes to virus-mediated apoptosis through binding to its target gene Bax in influenza A virus infection.
Nanobody-based sandwich reporter system for living cell sensing influenza A virus infection.
Nuclear MxA proteins form a complex with influenza virus NP and inhibit the transcription of the engineered influenza virus genome.
Oxymatrine Inhibits Influenza A Virus Replication and Inflammation via TLR4, p38 MAPK and NF-?B Pathways.
Polygonum cuspidatum and Its Active Components Inhibit Replication of the Influenza Virus through Toll-Like Receptor 9-Induced Interferon Beta Expression.
Replication and transcription activities of ribonucleoprotein complexes reconstituted from avian H5N1, H1N1pdm09 and H3N2 influenza A viruses.
Replication-Competent ?NS1 Influenza A Viruses Expressing Reporter Genes.
Replication-Competent Influenza Virus and Respiratory Syncytial Virus Luciferase Reporter Strains Engineered for Co-Infections Identify Antiviral Compounds in Combination Screens.
Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein.
Visualizing influenza virus infection in living mice.
Visualizing real-time influenza virus infection, transmission and protection in ferrets.
[Establishment of drug screening assay and pharmacodynamic evaluation method targeting influenza RNA polymerase].
Insulin Resistance
Age, obesity, and sex effects on insulin sensitivity and skeletal muscle mitochondrial function.
Yunpi Heluo decoction attenuates insulin resistance by regulating liver miR-29a-3p in Zucker diabetic fatty rats.
Insulinoma
A variant insulin promoter in non-insulin-dependent diabetes mellitus.
Activation of gastrin transcription in pancreatic insulinoma cells by a CACC promoter element and a 70-kDa sequence-specific DNA-binding protein.
Anti-GAD antibody targeted non-viral gene delivery to islet beta cells.
Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element.
Identification and functional characterization of the bovine manganous superoxide dismutase promoter.
Localization and regulation of pancreatic selenoprotein P.
Organ-specific autoantibodies in Chinese patients newly diagnosed with type 1 diabetes mellitus.
Prolactin induction of insulin gene transcription: roles of glucose and signal transducer and activator of transcription 5.
Recombinant expression of biologically active rat leptin in Escherichia coli.
System for exposing cultured cells to intermittent hypoxia utilizing gas permeable cultureware.
The multiple endocrine neoplasia type 1 gene product, menin, inhibits insulin production in rat insulinoma cells.
Intervertebral Disc Degeneration
Cartilage Intermediate Layer Protein (CILP) Regulation in Intervertebral Discs: The Effect of Age, Degeneration, and BMP-2.
Transcription factor 7-like 2 controls matrix degradation through nuclear factor ?B signaling and is repressed by microRNA-155 in nucleus pulposus cells.
Intestinal Neoplasms
Cloning and functional characterization of the human VIP1/PACAP receptor promoter.
Intestinal Volvulus
A Four-Antigen Mixture for Rapid Assessment of Onchocerca volvulus Infection.
Rapid, novel, specific, high-throughput assay for diagnosis of Loa loa infection.
Intracranial Aneurysm
MicroRNA-92a Regulates Expression of Kruppel-like Factor2 in Rabbit Model of Intracranial Aneurysm.
Iron Deficiencies
Role of hypoxia-inducible factor-1 in transcriptional activation of ceruloplasmin by iron deficiency.
Ischemic Stroke
Downregulation of miRNA-134 protects neural cells against ischemic injury in N2A cells and mouse brain with ischemic stroke by targeting HSPA12B.
LncRNA GAS5 regulates ischemic stroke as a competing endogenous RNA for miR-137 to regulate the Notch1 signaling pathway.
LncRNA SNHG6 functions as a ceRNA to regulate neuronal cell apoptosis by modulating miR-181c-5p/BIM signalling in ischaemic stroke.
Long Non-coding RNA PVT1 Inhibits miR-30c-5p to Upregulate Rock2 to Modulate Cerebral Ischemia/Reperfusion Injury Through MAPK Signaling Pathway Activation.
MicroRNA-195 protection against focal cerebral ischemia by targeting CX3CR1.
Keloid
MiR-181a Targets PHLPP2 to Augment AKT Signaling and Regulate Proliferation and Apoptosis in Human Keloid Fibroblasts.
Peroxisome proliferator-activated receptor-? agonist troglitazone suppresses transforming growth factor-?1 signalling through miR-92b upregulation-inhibited Axl expression in human keloid fibroblasts in vitro.
The aldo-keto reductase AKR1B10 is upregulated in keloid epidermis, implicating retinoic acid pathway dysregulation in the pathogenesis of keloid disease.
Upregulation of microRNA-205 suppresses vascular endothelial growth factor expression-mediated PI3K/Akt signaling transduction in human keloid fibroblasts.
Kidney Failure, Chronic
Functional analysis of promoter mutations in the ACTN4 and SYNPO genes in focal segmental glomerulosclerosis.
Kidney Neoplasms
A novel bioluminescent tumor model of human renal cancer cell lines: an in vitro and in vivo characterization.
Combined cryoablation and GM-CSF treatment for metastatic hormone refractory prostate cancer.
Immunologic response to primary cryoablation of high-risk prostate cancer.
MicroRNA-1826 directly targets beta-catenin (CTNNB1) and MEK1 (MAP2K1) in VHL-inactivated renal cancer.
MicroRNA-205 Inhibits Src-Mediated Oncogenic Pathways in Renal Cancer.
MiR-506 is down-regulated in clear cell renal cell carcinoma and inhibits cell growth and metastasis via targeting FLOT1.
miRNA-221 promotes proliferation, migration and invasion by targeting TIMP2 in renal cell carcinoma.
Monitoring luciferase-labeled cancer cell growth and metastasis in different in vivo models.
Klatskin Tumor
miR-373 Negatively Regulates Methyl-CpG-Binding Domain Protein 2 (MBD2) in Hilar Cholangiocarcinoma.
Laryngeal Neoplasms
LncRNA WTAPP1 promotes proliferation of laryngeal carcinoma cells through regulating microRNA-592.
S100A4 is upregulated via the binding of c-Myb in methylation-free laryngeal cancer cells.
Whole-Transcriptome Analysis of CD133+CD144+ Cancer Stem Cells Derived from Human Laryngeal Squamous Cell Carcinoma Cells.
[Effect of miR-340-5p on proliferation of laryngeal cancer Hep2 cells and its intrinsic molecular mechanism].
Latent Infection
Herpesvirus saimiri-based vector biodistribution using noninvasive optical imaging.
HIV latency can be established in proliferating and nonproliferating resting CD4+ T cells in vitro: implications for latency reversal.
The HSV-1 Latency-Associated Transcript Functions to Repress Latent Phase Lytic Gene Expression and Suppress Virus Reactivation from Latently Infected Neurons.
Leiomyoma
A-Kinase Anchoring Protein 13 (AKAP13) Augments Progesterone Signaling in Uterine Fibroid Cells.
Adenovirus-mediated delivery of a dominant-negative estrogen receptor gene in uterine leiomyoma cells abrogates estrogen- and progesterone-regulated gene expression.
Cross-talk between miR-29c and transforming growth factor-?3 is mediated by an epigenetic mechanism in leiomyoma.
Natural Antioxidant Resveratrol Suppresses Uterine Fibroid Cell Growth and Extracellular Matrix Formation In Vitro and In Vivo.
Toward gene therapy of uterine fibroids: targeting modified adenovirus to human leiomyoma cells.
Leishmaniasis
EGFP reporter protein: its immunogenicity in Leishmania-infected BALB/c mice.
Generation of luciferase-expressing Leishmania infantum chagasi and assessment of miltefosine efficacy in infected hamsters through bioimaging.
In Vitro Infections of Macrophage-Like Cell Lines with Leishmania infantum for Drug Screening.
Leishmaniasis, Cutaneous
A Luciferase-Expressing Leishmania braziliensis Line That Leads to Sustained Skin Lesions in BALB/c Mice and Allows Monitoring of Miltefosine Treatment Outcome.
Evaluation of NanoLuc, RedLuc and Luc2 as bioluminescent reporters in a cutaneous leishmaniasis model.
Leishmaniasis, Visceral
Generation of luciferase-expressing Leishmania infantum chagasi and assessment of miltefosine efficacy in infected hamsters through bioimaging.
Imaging visceral leishmaniasis in real time with golden hamster model: Monitoring the parasite burden and hamster transcripts to further characterize the immunological responses of the host.
Lentivirus Infections
Hemin impairs resolution of inflammation via microRNA-144-3p-dependent downregulation of ALX/FPR2.
NF-?B and pSTAT3 synergistically drive G6PD overexpression and facilitate sensitivity to G6PD inhibition in ccRCC.
Leukemia
A common pro-opiomelanocortin-binding element mediates leukemia inhibitory factor and corticotropin-releasing hormone transcriptional synergy.
ALKBH2 inhibition alleviates malignancy in colorectal cancer by regulating BMI1-mediated activation of NF-?B pathway.
Amsacrine suppresses matrix metalloproteinase-2 (MMP-2)/MMP-9 expression in human leukemia cells.
An advanced preclinical mouse model for acute myeloid leukemia using patients' cells of various genetic subgroups and in vivo bioluminescence imaging.
Elusive Role of the CD94/NKG2C NK Cell Receptor in the Response to Cytomegalovirus: Novel Experimental Observations in a Reporter Cell System.
Evaluation of the in vitro antiretroviral potential of some Biginelli-type pyrimidines.
Evaluation of viral and mammalian promoters for use in gene delivery to salivary glands.
Genomic integration and gene expression by a modified adenoviral vector.
HLF/miR-132/TTK axis regulates cell proliferation, metastasis and radiosensitivity of glioma cells.
Human T-cell leukemia virus type-I (HTLV-I) tax is not the only one factor to enhance human immunodeficiency virus type-I (HIV-1) infection in culture-supernatants.
Identification of the suppressive factors for human immunodeficiency virus type-1 replication using the siRNA mini-library directed against host cellular genes.
In Vivo Bioluminescence Imaging of Murine Xenograft Cancer Models with a Red-shifted Thermostable Luciferase.
Infection of cultured embryo cells of the pacific oyster, Crassostrea gigas, by pantropic retroviral vectors.
Integration of the hybrid adenoretroviral vector AdLTR-luc involves both MoMLV elements flanking the transgene.
Investigating antibody neutralization of lyssaviruses using lentiviral pseudotypes: a cross-species comparison.
Isolation and characterization of the chicken m2 acetylcholine receptor promoter region: induction of gene transcription by leukemia inhibitory factor and ciliary neurotrophic factor.
MicroRNA-1246 by Targeting AXIN2 and GSK-3? Overcomes Drug Resistance and Induces Apoptosis in Chemo-resistant Leukemia Cells.
MicroRNA-200c suppresses cell growth and metastasis by targeting Bmi-1 and E2F3 in renal cancer cells.
MicroRNA-33b regulates hepatocellular carcinoma cell proliferation, apoptosis, and mobility via targeting Fli-1-mediated Notch1 pathway.
MicroRNA-638 inhibits cell proliferation by targeting suppress PIM1 expression in human osteosarcoma.
MicroRNA-98 Inhibits Hepatic Stellate Cell Activation and Attenuates Liver Fibrosis by Regulating HLF Expression.
MiR-24-3p attenuates IL-1?-induced chondrocyte injury associated with osteoarthritis by targeting BCL2L12.
Molecular parameters of siRNA--cell penetrating peptide nanocomplexes for efficient cellular delivery.
Novel ring A stereoisomers of 2-methyl-1alpha,25-dihydroxyvitamin D(3) and 2-methyl-20-epi-1alpha,25-dihydroxyvitamin D(3): transactivation of target genes and modulation of differentiation in human promyelocytic leukemia (HL-60) cells.
Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia.
Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting.
Reporter gene expression in fish following cutaneous infection with pantropic retroviral vectors.
Silencing of long noncoding INHBA antisense RNA1 suppresses proliferation, migration, and extracellular matrix deposition in human hypertrophic scar fibroblasts via regulating microRNA-141-3p/myeloid cell leukemia 1 axis.
Sodium lauryl sulfate abrogates human immunodeficiency virus infectivity by affecting viral attachment.
Sulfatide inhibits HIV-1 entry into CD4-/CXCR4+ cells.
SUMO conjugation contributes to immune deviation in nonobese diabetic mice by suppressing c-Maf transactivation of IL-4.
The proximal promoter of the human cathepsin G gene conferring myeloid-specific expression includes C/EBP, c-myb and PU.1 binding sites.
The ring finger protein RNF6 induces leukemia cell proliferation as a direct target of pre-B-cell leukemia homeobox 1.
Transduction of Schistosoma mansoni by vesicular stomatitis virus glycoprotein-pseudotyped Moloney murine leukemia retrovirus.
Transfection of human endothelial cells with HIV-1 tat gene activates NF-kappa B and enhances monocyte adhesion.
Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity.
Upregulation of microRNA-125b by G-CSF promotes metastasis in colorectal cancer.
Vitamin B6 modulates glucocorticoid-dependent gene transcription in a promoter- and cell type-specific manner.
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors.
[Influence of AML1 and AML1-ETO on transcriptional regulation of nucb2 gene]
[Regulation mechanism for rig-g gene expression induced by all-trans retinoic acid]
Leukemia, B-Cell
MiR-24-3p attenuates IL-1?-induced chondrocyte injury associated with osteoarthritis by targeting BCL2L12.
Leukemia, Erythroblastic, Acute
Analysis of the megakaryocyte glycoprotein IX promoter identifies positive and negative regulatory domains and functional GATA and Ets sites.
Determinants of specific RNA interference-mediated silencing of human beta-globin alleles differing by a single nucleotide polymorphism.
Early growth response transcription factor EGR-1 regulates Galphaq gene in megakaryocytic cells.
Histones, protamine, and polylysine but not poly(E:K) enhance transfection efficiency.
Identification of a major positive regulatory element located 5' to the human zeta-globin gene.
Identification of essential GATA and Ets binding motifs within the promoter of the platelet glycoprotein Ib alpha gene.
Promoter activity of the 5' flanking region of the complement receptor type 1 (CR1) gene: basal and induced transcription.
Regulation of transcription of the glutathione S-transferase P1 gene by methylation of the minimal promoter in human leukemia cells.
RUNX1/core binding factor A2 regulates platelet 12-lipoxygenase gene (ALOX12): studies in human RUNX1 haplodeficiency.
The transcriptional regulation of human arachidonate 12-lipoxygenase gene by NF kappa B/Rel.
Transcription Factor RUNX1 Regulates Platelet PCTP (Phosphatidylcholine Transfer Protein): Implications for Cardiovascular Events: Differential Effects of RUNX1 Variants.
Transcriptional upregulation of gamma-globin by phenylbutyrate and analogous aromatic fatty acids.
Uroporphyrinogen III synthase. An alternative promoter controls erythroid-specific expression in the murine gene.
Leukemia, Monocytic, Acute
Identification of the suppressive factors for human immunodeficiency virus type-1 replication using the siRNA mini-library directed against host cellular genes.
In Vivo Bioluminescence Imaging of Murine Xenograft Cancer Models with a Red-shifted Thermostable Luciferase.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Identification of the human HEX1/hExo1 gene promoter and characterization of elements responsible for promoter activity.
Sp family members stimulate transcription of the hex gene via interactions with GC boxes.
Transcriptional attenuation of PIM-1 gene.
Leukemia, Myeloid
Inhibition of miR-302 Suppresses Hypoxia-Reoxygenation-Induced H9c2 Cardiomyocyte Death by Regulating Mcl-1 Expression.
Leukemia, Myeloid, Acute
E3 ligase SCFSKP2 ubiquitinates and degrades tumor suppressor C/EBP? in acute myeloid leukemia.
Leukemia, Promyelocytic, Acute
The proximal promoter of the human cathepsin G gene conferring myeloid-specific expression includes C/EBP, c-myb and PU.1 binding sites.
[Regulation mechanism for rig-g gene expression induced by all-trans retinoic acid]
Leukemia, T-Cell
Molecular cloning of a novel human I-mfa domain-containing protein that differently regulates human T-cell leukemia virus type I and HIV-1 expression.
Reevaluation of confirmatory tests for human T-cell leukemia virus Type 1 using a luciferase immunoprecipitation system in blood donors.
Leukemia-Lymphoma, Adult T-Cell
Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP).
Expression of parathyroid hormone-related protein during immortalization of human peripheral blood mononuclear cells by HTLV-1: implications for transformation.
Leukoplakia, Hairy
The Cancer-Associated Virus Landscape in HIV Patients with Oral Hairy Leukoplakia, Kaposi's Sarcoma, and Non-Hodgkin Lymphoma.
Leydig Cell Tumor
Association of TNP2 gene polymorphisms of the bta-miR-154 target site with the semen quality traits of Chinese Holstein bulls.
Liposarcoma
Characterization of a cholesterol response element (CRE) in the promoter of the cholesteryl ester transfer protein gene: functional role of the transcription factors SREBP-1a, -2, and YY1.
Liver Cirrhosis
Insulin-like growth factor I gene transfer to cirrhotic liver induces fibrolysis and reduces fibrogenesis leading to cirrhosis reversion in rats.
Liver transduction with a simian virus 40 vector encoding insulin-like growth factor I reduces hepatic damage and the development of liver cirrhosis.
MicroRNA-125a/VDR axis impaired autophagic flux and contributed to fibrosis in a CCL4-induced mouse model and patients with liver cirrhosis.
Liver Cirrhosis, Biliary
SP140L, an Evolutionarily Recent Member of the SP100 Family, Is an Autoantigen in Primary Biliary Cirrhosis.
Liver Neoplasms
A novel Romani microdeletion variant in the promoter sequence of ASS1 causes citrullinemia type I.
Antitumoral effects of recombinant adenovirus YKL-1001, conditionally replicating in alpha-fetoprotein-producing human liver cancer cells.
Cancer-selective induction of cytotoxicity by tissue-specific expression of targeted trans-splicing ribozyme.
CREB1 acts via the miR?922/ARID2 axis to enhance malignant behavior of liver cancer cells.
Environmental polycyclic aromatic hydrocarbons affect androgen receptor activation in vitro.
Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context.
Functional analysis of the human galactose-1-phosphate uridyltransferase promoter in Duarte and LA variant galactosemia.
Inactivation of lncRNA HOTAIRM1 caused by histone methyltransferase RIZ1 accelerated the proliferation and invasion of liver cancer.
Knockdown of otubain 2 inhibits liver cancer cell growth by suppressing NF-?B signaling.
lncRNA LOXL1-AS1 promotes liver cancer cell proliferation and migration by regulating the miR-377-3p/NFIB axis.
microRNA-22 downregulation of galectin-9 influences lymphocyte apoptosis and tumor cell proliferation in liver cancer.
MicroRNA-29c restores cisplatin sensitivity in liver cancer through direct inhibition of sirtuin 1 expression.
MiR-32 induces cell proliferation, migration, and invasion in hepatocellular carcinoma by targeting PTEN.
MiR-589-5p is a potential prognostic marker of hepatocellular carcinoma and regulates tumor cell growth by targeting MIG-6.
miRNA-99a inhibits cell invasion and migration in liver cancer by directly targeting HOXA1.
Regulation of UDP-Glucuronosyltransferases UGT2B4 and UGT2B7 by MicroRNAs in Liver Cancer Cells.
Restoration of RNA helicase DDX5 suppresses hepatitis B virus (HBV) biosynthesis and Wnt signaling in HBV-related hepatocellular carcinoma.
Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy.
Targeted gene therapy and in vivo bioluminescent imaging for monitoring postsurgical recurrence and metastasis in mouse models of liver cancer.
The potential mechanism of miR-130b on promotion of the invasion and metastasis of hepatocellular carcinoma by inhibiting Notch-Dll1.
Transcriptional regulation of urokinase-type plasminogen activator receptor by hypoxia-inducible factor 1 is crucial for invasion of pancreatic and liver cancer.
[Expression of fused luxAB gene of bacterial luciferase in liver carcinoma cells]
[Hepatitis B virus X protein upregulates the transcription activity of zinc finger transcription factor SNAI1]
[Regulation of Smad ubiquitination regulatory factor 1 expression by NF-?B].
Liver Neoplasms, Experimental
Imaging of hypoxia-driven gene expression in an orthotopic liver tumor model.
Lung Diseases, Interstitial
miR-21 Exerts Anti-proliferative and Pro-apoptotic Effects in LPS-induced WI-38 Cells via Directly Targeting TIMP3.
Lung Injury
Genetic Modification of Airway Progenitors Following Lentiviral Gene Delivery to the Amniotic Fluid of Murine Fetuses.
In Situ Pulmonary Localization of Air Pollution Particle-induced Oxidative Stress.
Increased serum miR-300 level serves as a potential biomarker of lipopolysaccharide-induced lung injury by targeting I?B?.
Lung Neoplasms
A functional polymorphism in the promoter of ERK5 gene interacts with tobacco smoking to increase the risk of lung cancer in Chinese populations.
A variant in 3'-untranslated region of KRAS compromises its interaction with hsa-let-7g and contributes to the development of lung cancer in patients with COPD.
Adenoviral melanoma differentiation-associated gene 7 induces apoptosis in lung cancer cells through mitochondrial permeability transition-independent cytochrome c release.
Analysis and Identification of Tumorigenic Targets of MicroRNA in Cancer Cells by Photoreactive Chemical Probes.
Anticancer cardamonin analogs suppress the activation of NF-kappaB pathway in lung cancer cells.
Aspirin ameliorates lung cancer by targeting the miR-98/WNT1 axis.
Aspirin-targeted PD-L1 in lung cancer growth inhibition.
Associations of MDM2 SNP309, transcriptional activity, mRNA expression, and survival in stage I non-small-cell lung cancer patients with wild-type p53 tumors.
Cancer-specific activation of the survivin promoter and its potential use in gene therapy.
Cancer-specific binary expression system activated in mice by bacteriophage HK022 Integrase.
Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation.
Combination of vorinostat and adenovirus-TRAIL exhibits a synergistic antitumor effect by increasing transduction and transcription of TRAIL in lung cancer cells.
Construction and application of an inducible system for homogenous expression levels in bulk cell lines.
CRKL promotes lung cancer cell invasion through ERK-MMP9 pathway.
Down-regulation of miR-675-5p contributes to tumor progression and development by targeting pro-tumorigenic GPR55 in non-small cell lung cancer.
Downregulation of AATK mediates microRNA-558-induced resistance of A549 cells to radiotherapy.
Early growth response-1 induces and enhances vascular endothelial growth factor-a expression in lung cancer cells.
Enhancement of GLI1-transcriptional activity by beta-catenin in human cancer cells.
Epidermal growth factor activates telomerase activity by direct binding of Ets-2 to hTERT promoter in lung cancer cells.
Exogenous Let-7a-5p Induces A549 Lung Cancer Cell Death Through BCL2L1-Mediated PI3K? Signaling Pathway.
Exploitation of a very small peptide nucleic acid as a new inhibitor of miR-509-3p involved in the regulation of cystic fibrosis disease-gene expression.
Expression of ABCG2 (BCRP) is regulated by Nrf2 in cancer cells that confers side population and chemoresistance phenotype.
Expression of G protein-coupled receptor 19 in human lung cancer cells is triggered by entry into S phase and supports G2/M cell cycle progression.
Expression of tdTomato and luciferase in a murine lung cancer alters the growth and immune microenvironment of the tumor.
Functional analysis of a lung cancer risk haplotype in the IL1B gene regulatory region.
Functional characterization of SNPs in CHRNA3/B4 intergenic region associated with drug behaviors.
Genetic Polymorphisms in the Apoptosis-Associated Gene CASP3 and the Risk of Lung Cancer in Chinese Population.
Heterogeneity of transcriptional activity of mutant p53 proteins and p53 DNA target sequences.
Highly expressed lncRNA FOXD3-AS1 promotes non-small cell lung cancer progression via regulating miR-127-3p/mediator complex subunit 28 axis.
Hyaluronic acid-conjugated lipoplexes for targeted delivery of siRNA in a murine metastatic lung cancer model.
Hydrophobic oxime ethers: a versatile class of pDNA and siRNA transfection lipids.
In vivo and in vitro effects of a HIF-1alpha inhibitor, RX-0047.
In vivo imaging models of bone and brain metastases and pleural carcinomatosis with a novel human EML4-ALK lung cancer cell line.
In vivo inhibition of lung cancer by GRN163L: a novel human telomerase inhibitor.
In vivo mouse ^{99m}Tc SPECT scans with bioluminescence imaging validation.
In vivo MRI for effective non-invasive detection and follow-up of an orthotopic mouse model of lung cancer.
Inhibition of microRNA-155 sensitizes lung cancer cells to irradiation via suppression of HK2-modulated glucose metabolism.
Luciferase assay to screen tumour-specific promoters in lung cancer.
Magnolin inhibits cell migration and invasion by targeting the ERKs/RSK2 signaling pathway.
Mechanisms of platelet-activating factor-induced enhancement of VEGF expression.
MicroRNA-128 promotes apoptosis in lung cancer by directly targeting NIMA-related kinase 2.
MicroRNA-202 induces cell cycle arrest and apoptosis in lung cancer cells through targeting cyclin D1.
MicroRNA-299-3p promotes the sensibility of lung cancer to doxorubicin through directly targeting ABCE1.
MicroRNA-361-3p suppresses tumor cell proliferation and metastasis by directly targeting SH2B1 in NSCLC.
MicroRNA-4458 suppresses the proliferation of human lung cancer cells in vitro by directly targeting Lin28B.
MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway.
MicroRNA-944 Affects Cell Growth by Targeting EPHA7 in Non-Small Cell Lung Cancer.
miR-1 Targeted Downregulation of Bcl-2 Increases Chemosensitivity of Lung Cancer Cells.
miR-181b inhibits chemoresistance in cisplatin-resistant H446 small cell lung cancer cells by targeting Bcl-2.
miR-30a suppresses lung cancer progression by targeting SIRT1.
miR-338-5p inhibits cell growth and migration via inhibition of the METTL3/m6A/c-Myc pathway in lung cancer.
miR141-CXCL1-CXCR2 signaling-induced Treg recruitment regulates metastases and survival of non-small cell lung cancer.
miR?195 suppresses metastasis and angiogenesis of squamous cell lung cancer by inhibiting the expression of VEGF.
miRNA-9 Inhibits Proliferation and Migration of Lung Squamous Cell Carcinoma Cells by Regulating NRSF/EGFR.
MnSOD Promotes Tumor Invasion via Upregulation of FoxM1-MMP2 Axis and Related with Poor Survival and Relapse in Lung Adenocarcinomas.
Monitoring with a non-invasive bioluminescentin vivoimaging system of pleural metastasis of lung carcinoma.
Noninvasive Bioluminescence Imaging of Matrix Metalloproteinase-14 Activity in Lung Cancer Using a Membrane-Bound Biosensor.
Oncogenic miR-19a and miR-19b co-regulate tumor suppressor MTUS1 to promote cell proliferation and migration in lung cancer.
p100 functions as a metastasis activator and is targeted by tumor suppressing microRNA-320a in lung cancer.
Polymorphisms in the promoter region of the neutrophil elastase gene are associated with lung cancer development.
Proliferation and Migration of Lung Cancer Could be Inhibited by Oxymatrine through the Regulation for miR-520/VEGF.
Promoter polymorphisms and transcript levels of nicotinic receptor CHRNA5.
Putative association of the single nucleotide polymorphisms in RASSF1A promoter with Korean lung cancer.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Selective Sp1 binding is critical for maximal activity of the human c-kit promoter.
Single nucleotide polymorphisms of the TGFB1 gene and lung cancer risk in a Korean population.
SOX17 methylation inhibits its antagonism of Wnt signaling pathway in lung cancer.
The Ancient Chinese Decoction Yu-Ping-Feng Suppresses Orthotopic Lewis Lung Cancer Tumor Growth Through Increasing M1 Macrophage Polarization and CD4+ T Cell Cytotoxicity.
The anti-infection drug furazolidone inhibits NF-?B signaling and induces cell apoptosis in small cell lung cancer.
The association and nuclear translocation of the PIAS3-STAT3 complex is ligand and time dependent.
The crosstalk between ?-catenin signaling and type I, type II and type III interferons in lung cancer cells.
The lncRNA myocardial infarction associated transcript-centric competing endogenous RNA network in non-small-cell lung cancer.
The miR-101/RUNX1 feedback regulatory loop modulates chemo-sensitivity and invasion in human lung cancer.
The novel microRNA hsa-miR-CHA1 regulates cell proliferation and apoptosis in human lung cancer by targeting XIAP.
Toxicological exploration of peptide-based cationic liposomes in siRNA delivery.
Transcriptional coactivator CBP upregulates hTERT expression and tumor growth and predicts poor prognosis in human lung cancers.
UBE2C, Directly Targeted by miR-548e-5p, Increases the Cellular Growth and Invasive Abilities of Cancer Cells Interacting with the EMT Marker Protein Zinc Finger E-box Binding Homeobox 1/2 in NSCLC.
Upregulation of Long Noncoding RNA GAS5 Inhibits Lung Cancer Cell Proliferation and Metastasis via miR-205/PTEN Axis.
Use of Tethered Enzymes as a Platform Technology for Rapid Analyte Detection.
[Cloning of human telomerase catalytic subunit gene promoter and studying on its specific transcriptional activities in human lung cancer cells.]
[Efficacy of RNA interference mediated by cationic liposomes].
[Establishment of a dual-fluorescence-traced lung cancer subcutaneous transplantation model in nude mice].
[Establishment of xenograft mouse models to study human lung cancer by using in vivo imaging system]
[Functional Bax polymorphism associated with lung cancer susceptibility]
[Study on cloning of hTERT promoter and its targeting transcriptional activities in telomerase-positive lung cancer cells]
Lyme Disease
Characterization of a Monanema nematode in Ixodes scapularis.
Disruption of bbe02 by Insertion of a Luciferase Gene Increases Transformation Efficiency of Borrelia burgdorferi and Allows Live Imaging in Lyme Disease Susceptible C3H Mice.
Rapid, Simple, Quantitative, and Highly Sensitive Antibody Detection for Lyme Disease.
Lymphatic Metastasis
A potent, imaging adenoviral vector driven by the cancer-selective mucin-1 promoter that targets breast cancer metastasis.
circLMTK2 acts as a sponge of miR-150-5p and promotes proliferation and metastasis in gastric cancer.
Circ_0000003 promotes the proliferation and metastasis of non-small cell lung cancer cells via miR-338-3p/insulin receptor substrate 2.
MicroRNA-106b promotes colorectal cancer cell migration and invasion by directly targeting DLC1.
microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN.
MicroRNA-301a promotes migration and invasion by targeting TGFBR2 in human colorectal cancer.
MicroRNA-30a Inhibits Colorectal Cancer Metastasis Through Down-Regulation of Type I Insulin-Like Growth Factor Receptor.
MicroRNA-361-3p suppresses tumor cell proliferation and metastasis by directly targeting SH2B1 in NSCLC.
MicroRNA-99a-5p suppresses cell proliferation, migration, and invasion by targeting isoprenylcysteine carboxylmethyltransferase in oral squamous cell carcinoma.
MicroRNA?936 inhibits the malignant phenotype of retinoblastoma by directly targeting HDAC9 and deactivating the PI3K/AKT pathway.
Overexpression of miR-191 Predicts Poor Prognosis and Promotes Proliferation and Invasion in Esophageal Squamous Cell Carcinoma.
Lymphoma
BG1 has a major role in MHC-linked resistance to malignant lymphoma in the chicken.
CircHmbox1 Targeting miRNA-1247-5p Is Involved in the Regulation of Bone Metabolism by TNF-? in Postmenopausal Osteoporosis.
Differentially expressed microRNA-218 modulates the viability of renal cell carcinoma by regulating BCL9.
Effects of paclitaxel combined with miR-448 on growth and proliferation of bladder cancer EJ cells.
Efficient adenovirus-mediated gene expression in malignant human plasma cells: relative lymphoid cell resistance.
Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1?DNMT3A??Np73 pathways.
Epstein-Barr Virus (EBV)-BamHI-A Rightward Transcript (BART)-6 and Cellular MicroRNA-142 Synergistically Compromise Immune Defense of Host Cells in EBV-Positive Burkitt Lymphoma.
GATA4 is highly expressed in childhood acute lymphoblastic leukemia, promotes cell proliferation and inhibits apoptosis by activating BCL2 and MDM2.
Hypoxia-mediated down-regulation of miRNAs' biogenesis promotes tumor immune escape in bladder cancer.
Intratumoral Accumulation and Clonal Expansion May Not Be Decisive for Rejection of Allogeneic Tumors by CD8+ T-Lymphocytes.
Irradiation with ultrasound of low output intensity increased chemosensitivity of subcutaneous solid tumors to an anti-cancer agent.
Large-scale preparation of recombinant ovine prolactin and determination of its in vitro and in vivo activity.
MicroRNA-150 enhances radiosensitivity by inhibiting the AKT pathway in NK/T cell lymphoma.
MicroRNA?27a promotes tumorigenesis via targeting AKT in triple negative breast cancer.
MiR-29c suppresses invasion and metastasis by targeting TIAM1 in nasopharyngeal carcinoma.
miR?21 attenuates contrast?induced renal cell apoptosis by targeting PDCD4.
Molecular and metabolic pathways mediating curative treatment of a non-Hodgkin B cell lymphoma by Sindbis viral vectors and anti-4-1BB monoclonal antibody.
Regulation of Id2 expression in EL4 T lymphoma cells overexpressing growth hormone.
Systemic administration of 3-bromopyruvate in treating disseminated aggressive lymphoma.
The identification of up-regulated ebv-miR-BHRF1-2-5p targeting MALT1 and ebv-miR-BHRF1-3 in the circulation of patients with multiple sclerosis.
Tumor burden influences exposure and response to rituximab: pharmacokinetic-pharmacodynamic modeling using a syngeneic bioluminescent murine model expressing human CD20.
Vitamin B6 modulates glucocorticoid-dependent gene transcription in a promoter- and cell type-specific manner.
Lymphoma, B-Cell
Bioengineering a unique deimmunized bispecific targeted toxin that simultaneously recognizes human CD22 and CD19 receptors in a mouse model of B-cell metastases.
Effects of paclitaxel combined with miR-448 on growth and proliferation of bladder cancer EJ cells.
GATA4 is highly expressed in childhood acute lymphoblastic leukemia, promotes cell proliferation and inhibits apoptosis by activating BCL2 and MDM2.
LINC00908 Promotes Diffuse Large B-Cell Lymphoma Development by Down-Regulating miR-671-5p.
LukS-PV-Regulated MicroRNA-125a-3p Promotes THP-1 Macrophages Differentiation and Apoptosis by Down-Regulating NF1 and Bcl-2.
MicroRNA-664a-3p inhibits the proliferation of ovarian granulosa cells in polycystic ovary syndrome and promotes apoptosis by targeting BCL2A1.
MicroRNA?27a promotes tumorigenesis via targeting AKT in triple negative breast cancer.
miR-365 induces hepatocellular carcinoma cell apoptosis through targeting Bcl-2.
miR-371-5p suppresses the proliferative and migratory capacity of human nasopharyngeal carcinoma by targeting BCL2.
miR-766-3p Targeting BCL9L Suppressed Tumorigenesis, Epithelial-Mesenchymal Transition, and Metastasis Through the ?-Catenin Signaling Pathway in Osteosarcoma Cells.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Lymphoma, Large B-Cell, Diffuse
LINC00908 Promotes Diffuse Large B-Cell Lymphoma Development by Down-Regulating miR-671-5p.
Lymphoma, Non-Hodgkin
Monitoring Disease Progression and Therapeutic Response in a Disseminated Tumor Model for Non-Hodgkin Lymphoma by Bioluminescence Imaging.
The Cancer-Associated Virus Landscape in HIV Patients with Oral Hairy Leukoplakia, Kaposi's Sarcoma, and Non-Hodgkin Lymphoma.
Lymphoma, T-Cell
MiR-29c suppresses invasion and metastasis by targeting TIAM1 in nasopharyngeal carcinoma.
Macular Degeneration
1,25-Dihydroxyvitamin D decreases HTRA1 promoter activity in the rhesus monkey - A plausible explanation for the influence of vitamin D on age-related macular degeneration?
Malaria
Antileishmanial Activity of Compounds Derived from the Medicines for Malaria Venture Open Access Box Against Intracellular Leishmania major Amastigotes.
Bioluminescence Imaging of P. berghei Schizont Sequestration in Rodents.
Enlightening the malaria parasite life cycle: bioluminescent Plasmodium in fundamental and applied research.
Identification of pre-erythrocytic malaria antigens that target hepatocytes for killing in vivo and contribute to protection elicited by whole-parasite vaccination.
Real-time in vivo imaging of transgenic bioluminescent blood stages of rodent malaria parasites in mice.
Superior Pyronaridine Single-Dose Pharmacodynamics Compared to Artesunate, Chloroquine, and Amodiaquine in a Murine Malaria Luciferase Model.
Visualization of Malaria Parasites in the Skin Using the Luciferase Transgenic Parasite, Plasmodium berghei.
Malaria, Cerebral
Promoter polymorphism of the anion-exchange protein 1 associated with severe malarial anemia and fatality.
Massive Hepatic Necrosis
Treatment of murine fulminant hepatitis with genetically engineered endothelial progenitor cells.
Mastitis
Regulatory mutations in the A2M gene are involved in the mastitis susceptibility in dairy cows.
Mastocytoma
Involvement of transcription factor encoded by the mi locus in the expression of c-kit receptor tyrosine kinase in cultured mast cells of mice.
The site of administration influences both the type and the magnitude of the immune response induced by DNA vaccine electroporation.
Mastocytosis, Systemic
A new humanized in vivo model of KIT D816V+ advanced systemic mastocytosis monitored using a secreted luciferase.
Measles
Enhanced Gene Silencing in Cells Cured of Persistent Virus Infection by RNA Interference.
HSP90 Chaperoning in Addition to Phosphoprotein Required for Folding but Not for Supporting Enzymatic Activities of Measles and Nipah Virus L Polymerases.
Medulloblastoma
INSM1 Promoter-Driven Adenoviral Herpes Simplex Virus Thymidine Kinase Cancer Gene Therapy for the Treatment of Primitive Neuroectodermal Tumors.
MiR-22 is Frequently Down-regulated in Medulloblastomas, and Inhibits Cell Proliferation via the Novel Target PAPST1.
MiR-495 is a Predictive Biomarker that Downregulates GFI1 Expression in Medulloblastoma.
New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer.
Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma.
Targeted Brain Tumor Therapy by Inhibiting the MDM2 Oncogene: In Vitro and In Vivo Antitumor Activity and Mechanism of Action.
VIP receptor 1 (VPAC1) promoter targets the expression of a reporter gene to cerebellum and adrenal medulla in transgenic mice.
Melanoma
A novel attenuated replication-competent adenovirus for melanoma therapy.
A novel Romani microdeletion variant in the promoter sequence of ASS1 causes citrullinemia type I.
A reliable set of reference genes to normalize oxygen-dependent cytoglobin gene expression levels in melanoma.
Accuracy of spiked cell counting methods for designing a pre-clinical tumorigenicity study model.
Activated air produced by shielded sliding discharge plasma mediates plasmid DNA delivery to mammalian cells.
Amplification of transgene expression in vitro and in vivo using a novel inhibitor of histone deacetylase.
Anti-oncogenic MicroRNA-203 Induces Senescence by Targeting E2F3 in Human Melanoma Cells.
Antimelanogenesis Effects of Theasinensin A.
Antitumor activity of miR-1280 in melanoma by regulation of Src.
AP-1 and C/EBP transcription factors contribute to mda-7 gene promoter activity during human melanoma differentiation.
Assessment of melanoma extent and melanoma metastases invasion using electron paramagnetic resonance and bioluminescence imaging.
Augmentation of melanoma-specific gene expression using a tandem melanocyte-specific enhancer results in increased cytotoxicity of the purine nucleoside phosphorylase gene in melanoma.
Benzimidazoles Downregulate Mdm2 and MdmX and Activate p53 in MdmX Overexpressing Tumor Cells.
Bioluminescence imaging reveals inhibition of tumor cell proliferation by Alzheimer's amyloid beta protein.
Bispecific anti-CD3 x anti-B7-H3 antibody mediates T cell cytotoxic ability to human melanoma in vitro and in vivo.
Cellular Delivery and Biological Activity of Antisense Oligonucleotides Conjugated to a Targeted Protein Carrier.
Characterization of the integrin alpha(v) gene promoter in mice.
Chemosensitizing Effect of Saikosaponin B on B16F10 Melanoma Cells.
CircHIPK3 regulates melanoma cell behaviors by binding with miR-215-5p to upregulate YY1.
CIZ/NMP4 is expressed in B16 melanoma and forms a positive feedback loop with RANKL to promote migration of the melanoma cells.
Cloning and analysis of MART-1/Melan-A human melanoma antigen promoter regions.
Cloning of the human DOPAchrome tautomerase/tyrosinase-related protein 2 gene and identification of two regulatory regions required for its pigment cell-specific expression.
Cyclooxygenase-2 promoter for tumour-specific targeting of adenoviral vectors to melanoma.
Dacarbazine causes transcriptional up-regulation of interleukin 8 and vascular endothelial growth factor in melanoma cells: a possible escape mechanism from chemotherapy.
Development of a melanoma-specific adenovirus.
EBV replicon vector system enhances transgene expression in vivo: applications to cancer gene therapy.
Enhanced transgene expression and effective in vivo antitumor immune responses initiated by dendritic progenitors transfected with a nonviral T7 vector expressing a model tumor antigen.
Evaluation of tumor-specific promoter activities in melanoma.
Expression levels of microRNA?455 and its potential functions by targeting IGF?1R in melanoma.
FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells.
FOXD3-AS1 Contributes to the Progression of Melanoma Via miR-127-3p/FJX1 Axis.
Gene silencing in primary and metastatic tumors by small interfering RNA delivery in mice: quantitative analysis using melanoma cells expressing firefly and sea pansy luciferases.
High gene expression of the mutant adenovirus vector, both in vitro and in vivo, with the insertion of integrin-targeting peptide into the fiber.
Human macrophage inflammatory protein-3alpha/CCL20/LARC/Exodus/SCYA20 is transcriptionally upregulated by tumor necrosis factor-alpha via a non-standard NF-kappaB site.
Hunchback sequence binding protein suppresses mouse TGF-beta3 promoter in vitro.
Identification of a cis-acting element that enhances the pigment cell-specific expression of the human tyrosinase gene.
Identification of Pirin as a Molecular Target of the CCG-1423/CCG-203971 Series of Antifibrotic and Antimetastatic Compounds.
Imaging of Firefly Luciferase Activity under Antiangiogenic Therapy in a Heat Shock Protein 70-Transfected Melanoma Tumor Model.
Immune evasion by murine melanoma mediated through CC chemokine receptor-10.
In vitro and in vivo transfection of plasmid DNA in the Dunning prostate tumor R3327-AT1 is enhanced by focused ultrasound.
Inhibition of peritoneal dissemination of tumor cells by cationized catalase in mice.
Isoliquiritigenin suppresses human melanoma growth by targeting miR-301b/LRIG1 signaling.
L-Theanine inhibits melanoma cell growth and migration via regulating expression of the clock gene BMAL1.
Lipopolyplexes comprising imidazole/imidazolium lipophosphoramidate, histidinylated polyethyleneimine and siRNA as efficient formulation for siRNA transfection.
Long non-coding RNA H19 promotes glucose metabolism and cell growth in malignant melanoma via miR-106a-5p/E2F3 axis.
Long non-coding RNA LINC00520 promotes the proliferation and metastasis of malignant melanoma by inducing the miR-125b-5p/EIF5A2 axis.
Long noncoding RNA LINC00518 acts as a competing endogenous RNA to promote the metastasis of malignant melanoma via miR-204-5p/AP1S2 axis.
Loss of activator protein-2alpha results in overexpression of protease-activated receptor-1 and correlates with the malignant phenotype of human melanoma.
Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis.
Luciferase activity as a marker of tumor burden and as an indicator of tumor response to antineoplastic therapy in vivo.
Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo.
Melatonin synergizes BRAF-targeting agent vemurafenib in melanoma treatment by inhibiting iNOS/hTERT signaling and cancer-stem cell traits.
Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.
MicroRNA-195 acts as an anti-proliferative miRNA in human melanoma cells by targeting Prohibitin 1.
MicroRNA-22 targets FMNL2 to inhibit melanoma progression via the regulation of the Wnt/?-catenin signaling pathway and epithelial-mesenchymal transition.
MicroRNA-222 influences migration and invasion through MIA3 in colorectal cancer.
microRNA-625 inhibits tumorigenicity by suppressing proliferation, migration and invasion in malignant melanoma.
MicroRNA-633 enhances melanoma cell proliferation and migration by suppressing KAI1.
MicroRNA-663 Regulates Melanoma Progression by Inhibiting FHL3.
MicroRNA?675 inhibits cell proliferation and invasion in melanoma by directly targeting metadherin.
MiR-155 inhibits proliferation, invasion and migration of melanoma via targeting CBL.
miR-205 suppresses melanoma cell proliferation and induces senescence via regulation of E2F1.
miR-20b regulates expression of proteinase-activated receptor-1 (PAR-1) thrombin receptor in melanoma cells.
MiR-26b inhibits melanoma cell proliferation and enhances apoptosis by suppressing TRAF5-mediated MAPK activation.
miR-302a-3p suppresses melanoma cell progression via targeting METTL3.
miR-33a is downregulated in melanoma cells and modulates cell proliferation by targeting PCTAIRE1.
miR-425 inhibits melanoma metastasis through repression of PI3K-Akt pathway by targeting IGF-1.
miR-652 Promotes Proliferation and Migration of Uveal Melanoma Cells by Targeting HOXA9.
miR?367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression.
mPEG-PAMAM-G4 nucleic acid nanocomplexes: enhanced stability, rnase protection, and activity of splice switching oligomer and poly I:C RNA.
Multivalent Cyclic RGD Conjugates for Targeted Delivery of Small Interfering RNA.
Myeloid expression of adenosine A2A receptor suppresses T and NK cell responses in the solid tumor microenvironment.
Novel mechanisms of resistance to vemurafenib in melanoma - V600E B-Raf reversion and switching VEGF-A splice isoform expression.
Pharmacokinetic modeling of tumor bioluminescence implicates efflux, and not influx, as the bigger hurdle in cancer drug therapy.
Preclinical evaluation of cancer immune therapy using patient-derived tumor antigen-specific T cells in a novel xenograft platform.
Prevention of pulmonary metastasis from subcutaneous tumors by binary system-based sustained delivery of catalase.
Proof of concept studies for siRNA delivery by non-ionic surfactant vesicles: in vitro and in vivo evaluation of protein knockdown.
Regulation of mda-7 gene expression during human melanoma differentiation.
RGD-based active targeting of novel polycation liposomes bearing siRNA for cancer treatment.
Selective induction of apoptosis in melanoma cells by tyrosinase promoter-controlled CD95 ligand overexpression.
Structure and transcriptional regulation of human alpha-mannosidase IIX (alpha-mannosidase II isotype) gene.
Studies on the transfer of DNA into cells through use of avidin-polylysine conjugates complexed to biotinylated transferrin and DNA.
Suppression effect of a dual cancer-specific oncolytic adenovirus on luciferase-labeled human melanoma cells in vitro and in vivo.
Suppression of connexin 43 expression by miR-106a promotes melanoma cell proliferation.
Suppression of IGF1R in Melanoma Cells by an Adenovirus-Mediated One-Step Knockdown System.
Synergistic activation of interleukin-8 gene transcription by all-trans-retinoic acid and tumor necrosis factor-alpha involves the transcription factor NF-kappaB.
Synergistic inhibition of human melanoma proliferation by combination treatment with B-Raf inhibitor BAY43-9006 and mTOR inhibitor Rapamycin.
Targeting GOLM1 by microRNA-200a in melanoma suppresses cell proliferation, invasion and migration via regulating PI3K/Akt signaling pathway and epithelial-mesenchymal transition.
The dietary flavonoid isoliquiritigenin induced apoptosis and suppressed metastasis in melanoma cells: An in vitro and in vivo study.
The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems.
The LncRNA MIR155HG is Upregulated by SP1 in Melanoma Cells and Drives Melanoma Progression via Modulating the MiR-485-3p/PSIP1 Axis.
TRAF6 Activates Fibroblasts to Cancer-Associated Fibroblasts through FGF19 in Tumor Microenvironment to Benefit the Malignant Phenotype of Melanoma Cells.
Transcriptional control analyses of the Xiphophorus melanoma oncogene.
Transcriptional targeting of tumors with a novel tumor-specific survivin promoter.
Translational control of tumor necrosis factor-related apoptosis-inducing ligand death receptor expression in melanoma cells.
Tumor-targeting TRAIL expression mediated by miRNA response elements suppressed growth of uveal melanoma cells.
Whole-body bioluminescent imaging of human uveal melanoma in a new mouse model of local tumor growth and metastasis.
ZFPM2-AS1 facilitates cell proliferation and migration in cutaneous malignant melanoma through modulating miR-650/NOTCH1 signaling.
[miR-122-5p inhibits the proliferation of melanoma cells by targeting NOP14].
[Modulation of Luciferase Production in Melanoma Cells in vitro].
Melanoma, Experimental
Assessment of melanoma extent and melanoma metastases invasion using electron paramagnetic resonance and bioluminescence imaging.
Chitosan nanoparticles for siRNA delivery: optimizing formulation to increase stability and efficiency.
Chromosomal localization and genomic characterization of the mouse melastatin gene (Mlsn1).
Effective delivery of DNA into tumor cells and tissues by electroporation of polymer-DNA complex.
Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.
Saporin suicide gene therapy.
The influences of a novel anti-adhesion device, thermally cross-linked gelatin film on peritoneal dissemination of tumor cells: The in vitro and in vivo experiments using murine carcinomatous peritonitis models.
MELAS Syndrome
Cerebrospinal fluid ATP as a potential biomarker in patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke like episodes (MELAS).
Meningioma
A novel model of intracranial meningioma in mice using luciferase-expressing meningioma cells. Laboratory investigation.
MiR-34a-3p alters proliferation and apoptosis of meningioma cells in vitro and is directly targeting SMAD4, FRAT1 and BCL2.
Oncolytic virotherapy of meningiomas in vitro with replication-competent adenovirus.
Mesothelioma
A Unique Gene-Silencing Approach, Using an Intelligent RNA Expression Device (iRed), Results in Minimal Immune Stimulation When Given by Local Intrapleural Injection in Malignant Pleural Mesothelioma.
CK2¿, over-expressed in human malignant pleural mesothelioma, regulates the Hedgehog signaling pathway in mesothelioma cells.
Complete regression of human malignant mesothelioma xenografts following local injection of midkine promoter-driven oncolytic adenovirus.
Gene therapy of experimental malignant mesothelioma using adenovirus vectors encoding the HSVtk gene.
Imatinib mesylate enhances therapeutic effects of gemcitabine in human malignant mesothelioma xenografts.
Mesothelioma, Malignant
CK2¿, over-expressed in human malignant pleural mesothelioma, regulates the Hedgehog signaling pathway in mesothelioma cells.
Metabolic Diseases
In vivo monitoring of pancreatic beta-cells in a transgenic mouse model.
Metabolic Syndrome
?-Mangostin from Garcinia mangostana pericarps as a dual agonist that activates Both PPAR? and PPAR?.
Microphthalmos
Role of microRNA508-3p in melanogenesis by targeting microphthalmia transcription factor in melanocytes of alpaca.
Mouth Diseases
Promotion of viral IRES-mediated translation under amino acid starvation.
Mouth Neoplasms
Activation of iCaspase-9 in neovessels inhibits oral tumor progression.
Antimetastatic effects of Rheum palmatum L. extract on oral cancer cells.
Characterization of a novel diolein-based LPDII vector for gene delivery.
circVAPA promotes the proliferation, migration and invasion of oral cancer cells through the miR-132/HOXA7 axis.
FOXD1 Repression Potentiates Radiation Effectiveness by Downregulating G3BP2 Expression and Promoting the Activation of TXNIP-Related Pathways in Oral Cancer.
Functional activation of PPAR? in human upper aerodigestive cancer cell lines.
Integrated genomic analyses identify KDM1A's role in cell proliferation via modulating E2F signaling activity and associate with poor clinical outcome in oral cancer.
Ligand/PTC-free intramolecular Heck reaction: synthesis of pyrroloquinoxalines and their evaluation against PDE4/luciferase/oral cancer cell growth in vitro and zebrafish in vivo.
MicroRNA-200c suppresses tumor metastasis in oral squamous carcinoma by inhibiting epithelial-mesenchymal transition.
MicroRNA-205 suppresses the oral carcinoma oncogenic activity via down-regulation of Axin-2 in KB human oral cancer cell.
Mutations in the long control region of human papillomavirus DNA in oral cancer cells, and their functional consequences.
OncomiR-196 promotes an invasive phenotype in oral cancer through the NME4-JNK-TIMP1-MMP signaling pathway.
Receptor-targeted gene delivery via folate-conjugated polyethylenimine.
Serum decreases the size of Metafectene-and Genejammer-DNA complexes but does not affect significantly their transfection activity in SCCVII murine squamous cell carcinoma cells.
Suppression of Oral Carcinoma Oncogenic Activity by microRNA-203
[Effect of mi-138 targeting PLD2 gene on proliferation and migration of oral cancer cells].
Multiple Myeloma
MicroRNA conjugated gold nanoparticles and cell transfection.
Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma.
Role of B-cell-activating factor in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment.
The effects of promoter methylation on downregulation of DAZAP2 in multiple myeloma cell lines.
[Mechanism and Clinical Significance of miR-373 In Elderly Patients with Multiple Myeloma].
Multiple Sclerosis
Impaired neurosteroid synthesis in multiple sclerosis.
Treatment of autoimmune disease by adoptive cellular gene therapy.
Validating parameters of a luciferase reporter gene assay to measure neutralizing antibodies to IFNbeta in multiple sclerosis patients.
Muscular Atrophy
Denervation drives skeletal muscle atrophy and induces mitochondrial dysfunction, mitophagy and apoptosis via miR-142a-5p/MFN1 axis.
Generation of reporter cell lines for factors inducing muscle wasting in cancer cachexia.
Mycoses
A multifunctional, synthetic Gaussia princeps luciferase reporter for live imaging of Candida albicans infections.
Myocardial Infarction
A transgenic mouse model for the simultaneous monitoring of ANF and BNP gene activity during heart development and disease.
Caught in the act: in vivo molecular imaging of the transcription factor NF-kappaB after myocardial infarction.
Cell sheet formation enhances the therapeutic effects of human umbilical cord mesenchymal stem cells on myocardial infarction as a bioactive material.
miR-129 Attenuates Myocardial Ischemia Reperfusion Injury by Regulating the Expression of PTEN in Rats.
MiR-30d inhibits cardiomyocytes autophagy promoting ferroptosis after myocardial infarction.
Multimodality evaluation of the viability of stem cells delivered into different zones of myocardial infarction.
Rs1894720 polymorphism in MIAT increased susceptibility to age-related hearing loss by modulating the activation of miR-29b/SIRT1/PGC-1? signaling.
[Bone mesenchymal stem cell transplantation for acute myocardial infarction: in vivo tracing with multi-modality molecular imaging].
Myocardial Ischemia
MicroRNA-384-5p regulates ischemia-induced cardioprotection by targeting phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (PI3K p110?).
Myocarditis
MicroRNA-425-3p inhibits myocardial inflammation and cardiomyocyte apoptosis in mice with viral myocarditis through targeting TGF-?1.
Nasal Polyps
Restoration of bacterial killing activity of human respiratory cystic fibrosis cells through cationic vector-mediated cystic fibrosis transmembrane conductance regulator gene transfer.
Nasopharyngeal Carcinoma
Identification and analysis of the promoter region of the STGC3 gene.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Nasopharyngeal Neoplasms
Identification and characterization of the hypoxia-responsive element in human stanniocalcin-1 gene.
Neoplasm Metastasis
A convenient clinically relevant model of human breast cancer bone metastasis.
A mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by Luciferase imaging.
A new liposomal formulation of Gemcitabine is active in an orthotopic mouse model of pancreatic cancer accessible to bioluminescence imaging.
A Novel Approach for Monitoring TGF-ß Signaling in vivo in Colon Cancer.
A potent, imaging adenoviral vector driven by the cancer-selective mucin-1 promoter that targets breast cancer metastasis.
A reciprocal feedback of Myc and lncRNA MTSS1-AS contributes to extracellular acidity-promoted metastasis of pancreatic cancer.
A viral microRNA downregulates metastasis suppressor CD82 and induces cell invasion and angiogenesis by activating the c-Met signaling.
Abrogation of prostaglandin E-EP4 signaling in osteoblasts prevents the bone destruction induced by human prostate cancer metastases.
Absence of EpCAM in cervical cancer cells is involved in sluginduced epithelial-mesenchymal transition.
Adenoviral vectors modified by heparin-polyethyleneimine nanogels enhance targeting to the lung and show therapeutic potential for pulmonary metastasis in vivo.
Adjuvant Trametinib Delays the Outgrowth of Occult Pancreatic Cancer in a Mouse Model of Patient-Derived Liver Metastasis.
Alkaline phosphatase downregulation promotes lung adenocarcinoma metastasis via the c-Myc/RhoA axis.
An orthotopic, postsurgical model of luciferase transfected murine osteosarcoma with spontaneous metastasis.
Angiotensin II promotes primary tumor growth and metastasis formation of murine TNBC 4T1 cells through the fibroblasts around cancer cells.
Animal models of bone metastasis.
Anticancer effects of tanshinone I in human non-small cell lung cancer.
Antitumor mechanism of MAP30 in bladder cancer T24 cells, and its potential toxic effects in mice.
Antrodia salmonea suppresses invasion and metastasis in triple-negative breast cancer cells by reversing EMT through the NF-?B and Wnt/?-catenin signaling pathway.
ASPH-notch Axis guided Exosomal delivery of Prometastatic Secretome renders breast Cancer multi-organ metastasis.
Assessment of melanoma extent and melanoma metastases invasion using electron paramagnetic resonance and bioluminescence imaging.
BET protein inhibitor JQ1 downregulates chromatin accessibility and suppresses metastasis of gastric cancer via inactivating RUNX2/NID1 signaling.
Bioluminescent imaging (BLI) to improve and refine traditional murine models of tumor growth and metastasis.
Bioluminescent orthotopic model of pancreatic cancer progression.
CAFs secreted exosomes promote metastasis and chemotherapy resistance by enhancing cell stemness and epithelial-mesenchymal transition in colorectal cancer.
Canine prostatic cancer cell line (LuMa) with osteoblastic bone metastasis.
Catalpol inhibits cell proliferation, invasion and migration through regulating miR-22-3p/MTA3 signalling in hepatocellular carcinoma.
CDK11p58 inhibits ER?-positive breast cancer invasion by targeting integrin ?3 via the repression of ER? signaling.
Characterization of two mouse models of metastatic pheochromocytoma using bioluminescence imaging.
circFBXW7 Inhibits Malignant Progression by Sponging miR-197-3p and Encoding a 185-aa Protein in Triple-Negative Breast Cancer.
circLMTK2 acts as a sponge of miR-150-5p and promotes proliferation and metastasis in gastric cancer.
Circular RNA circRGNEF promotes bladder cancer progression via miR-548/KIF2C axis regulation.
Circular RNA HIPK3 Promotes EMT of Cervical Cancer Through Sponging miR-338-3p to Up-Regulate HIF-1?.
Circ_0000003 promotes the proliferation and metastasis of non-small cell lung cancer cells via miR-338-3p/insulin receptor substrate 2.
Circ_0027599/PHDLA1 suppresses gastric cancer progression by sponging miR-101-3p.1.
Combination of Radiofrequency Ablation and Glycated Chitosan as Treatment on a Syngeneic Breast Tumor Model.
Comparison of three different methods for the detection of circulating tumor cells in mice with lung metastasis.
COX-2 involvement in breast cancer metastasis to bone.
Cryoablation and Meriva have strong therapeutic effect on triple-negative breast cancer.
Cryoimmunotherapy with local co-administration of ex vivo generated dendritic cells and CpG-ODN immune adjuvant, elicits a specific antitumor immunity.
Detection of Brain Tumors and Systemic Metastases Using NanoLuc and Fluc for Dual Reporter Imaging.
Development of a clinically relevant ovarian cancer model incorporating surgical cytoreduction to evaluate treatment of micro-metastatic disease.
Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts.
Different effect of paclitaxel on primary tumor mass, tumor cell contents, and metastases for four experimental human prostate tumors expressing luciferase.
Down-regulation of microRNA-34a-5p promotes trophoblast cell migration and invasion via targetting Smad4.
Downregulation of circ-TRPS1 suppressed prostatic cancer prognoses by regulating miR-124-3p/EZH2 axis-mediated stemness.
Downregulation of FOXO6 in breast cancer promotes epithelial-mesenchymal transition and facilitates migration and proliferation of cancer cells.
Downregulation of miR-542-3p promotes cancer metastasis through activating TGF-?/Smad signaling in hepatocellular carcinoma.
Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor??B signaling pathway.
Early administration of amatuximab, a chimeric high-affinity anti-mesothelin monoclonal antibody, suppresses liver metastasis of mesothelin-expressing pancreatic cancer cells and enhances gemcitabine sensitivity in a xenograft mouse model.
Effects of PEGylated paclitaxel nanocrystals on breast cancer and its lung metastasis.
Effects of VCP979 Novel p38 Mitogen Activated Protein Kinase Inhibitor on Progression of Pancreatic Cancer in Mouse Model with Diabetic Conditions.
Efficient in vivo microRNA targeting of liver metastasis.
Elevated expression of microRNA-328-3p suppresses aggressive malignant behaviors via targeting matrix metalloprotease 16 in osteosarcoma.
Enhanced transgene expression and effective in vivo antitumor immune responses initiated by dendritic progenitors transfected with a nonviral T7 vector expressing a model tumor antigen.
Epigenetic Silencing of miR-203 Upregulates SNAI2 and Contributes to the Invasiveness of Malignant Breast Cancer Cells.
Establishment of a bioluminescent MDA-MB-231 cell line for human triple-negative breast cancer research.
Establishment of Peritoneal and Hepatic Metastasis Mouse Xenograft Models Using Gastric Cancer Cell Lines.
Evaluation of a CXCR4 antagonist in a xenograft mouse model of inflammatory breast cancer.
Extended-release PEG-luciferin allows for long-term imaging of firefly luciferase activity in vivo.
Extracellular ubiquitin promotes hepatoma metastasis by mediating M2 macrophage polarization via the activation of the CXCR4/ERK signaling pathway.
FMNL1 Exhibits Pro-Metastatic Activity via CXCR2 in Clear Cell Renal Cell Carcinoma.
Gene transfer using liposome-complexed adenovirus seems to overcome limitations due to coxsackievirus and adenovirus receptor-deficiency of cancer cells, both in vitro and in vivo.
Host mediated anti-tumor effect of oncolytic Newcastle disease virus after locoregional application.
hsa?miR?24 suppresses metastasis in nasopharyngeal carcinoma by regulating the c?Myc/epithelial?mesenchymal transition axis.
Hypoxia-Inducible Exosomes Facilitate Liver-Tropic Premetastatic Niche in Colorectal Cancer.
Identification of Pirin as a Molecular Target of the CCG-1423/CCG-203971 Series of Antifibrotic and Antimetastatic Compounds.
Imaging of tumor clones with differential liver colonization.
In vivo anti-metastatic effects of uPAR retargeted measles virus in syngeneic and xenograft models of mammary cancer.
In vivo imaging models of bone and brain metastases and pleural carcinomatosis with a novel human EML4-ALK lung cancer cell line.
Inhibiting the redox function of APE1 suppresses cervical cancer metastasis via disengagement of ZEB1 from E-cadherin in EMT.
Inhibition of MDA-MB-231 breast cancer cell migration and invasion activity by andrographolide via suppression of nuclear factor-?B-dependent matrix metalloproteinase-9 expression.
Inhibition of Prostate Cancer Bone Metastasis by Synthetic TF Antigen Mimic/Galectin-3 Inhibitor Lactulose-l-Leucine.
Inhibitory effect of blue light emitting diode on migration and invasion of cancer cells.
Interleukin-17 promotes metastasis in an immunocompetent orthotopic mouse model of prostate cancer.
Involvement of IL-8 in COX-2-mediated bone metastases from breast cancer.
Knockdown of CD44 inhibits the invasion and metastasis of hepatocellular carcinoma both in vitro and in vivo by reversing epithelial-mesenchymal transition.
Linc00514 promotes breast cancer metastasis and M2 polarization of tumor-associated macrophages via Jagged1-mediated notch signaling pathway.
LINC01133 as ceRNA inhibits gastric cancer progression by sponging miR-106a-3p to regulate APC expression and the Wnt/?-catenin pathway.
lncRNA DUXAP8 Facilitates Multiple Malignant Phenotypes and Resistance to PARP Inhibitor in HCC via Upregulating FOXM1.
LncRNA FOXD3-AS1 Promotes the Malignant Progression of Nasopharyngeal Carcinoma Through Enhancing the Transcription of YBX1 by H3K27Ac Modification.
lncRNA PCNAP1 predicts poor prognosis in breast cancer and promotes cancer metastasis via miR?340?5p?dependent upregulation of SOX4.
Long non-coding RNA (LncRNA) MRPL23-AS1 promotes tumor progression and carcinogenesis in osteosarcoma by activating Wnt/?-catenin signaling via inhibiting microRNA miR-30b and upregulating myosin heavy chain 9 (MYH9).
Long noncoding RNA LINC01139 promotes the progression of hepatocellular carcinoma by upregulating MYBL2 via competitively binding to miR-30 family.
Long noncoding RNA ROR1-AS1 enhances lung adenocarcinoma metastasis and induces epithelial-mesenchymal transition by sponging miR-375.
Long noncoding RNA SLC30A10 promotes colorectal tumor proliferation and migration via miR-21c/APC axis.
LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis.
Mediation of circ_RPPH1 on miR-146b-3p/E2F2 pathway to hinder the growth and metastasis of breast carcinoma cells.
Micro-CT combined with bioluminescence imaging: a dynamic approach to detect early tumor-bone interaction in a tumor osteolysis murine model.
MicroRNA-106b promotes colorectal cancer cell migration and invasion by directly targeting DLC1.
MicroRNA-124-3p suppresses cell migration and invasion by targeting ITGA3 signaling in bladder cancer.
MicroRNA-125a-5p inhibits invasion and metastasis of gastric cancer cells by targeting BRMS1 expression.
MicroRNA-150 suppresses triple-negative breast cancer metastasis through targeting HMGA2.
MicroRNA-182-5p Modulates Oral Squamous Cell Carcinoma Migration and Invasion Via Targeting MTSS1 Gene.
MicroRNA-18a inhibits hypoxia-inducible factor 1? activity and lung metastasis in basal breast cancers.
microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN.
MicroRNA-26a induces osteosarcoma cell growth and metastasis via the Wnt/?-catenin pathway.
MicroRNA-301a promotes migration and invasion by targeting TGFBR2 in human colorectal cancer.
MicroRNA-30a Inhibits Colorectal Cancer Metastasis Through Down-Regulation of Type I Insulin-Like Growth Factor Receptor.
MicroRNA-361-3p suppresses tumor cell proliferation and metastasis by directly targeting SH2B1 in NSCLC.
MicroRNA-421 inhibits breast cancer metastasis by targeting metastasis associated 1.
MicroRNA-505 is downregulated in human osteosarcoma and regulates cell proliferation, migration and invasion.
MicroRNA-506 suppresses tumor proliferation and metastasis in colon cancer by directly targeting the oncogene EZH2.
MicroRNA-99a-5p suppresses cell proliferation, migration, and invasion by targeting isoprenylcysteine carboxylmethyltransferase in oral squamous cell carcinoma.
MicroRNA?4284 promotes gastric cancer tumorigenicity by targeting ten-eleven translocation 1.
MicroRNA?936 inhibits the malignant phenotype of retinoblastoma by directly targeting HDAC9 and deactivating the PI3K/AKT pathway.
miR-106b Promotes Metastasis of Early Gastric Cancer by Targeting ALEX1 in Vitro and in Vivo.
miR-124 inhibits proliferation, migration and invasion of malignant melanoma cells via targeting versican.
miR-124 targets GATA6 to suppress cholangiocarcinoma cell invasion and metastasis.
miR-1271 inhibits migration, invasion and epithelial-mesenchymal transition by targeting ZEB1 and TWIST1 in pancreatic cancer cells.
MiR-139-5p inhibits the biological function of breast cancer cells by targeting Notch1 and mediates chemosensitivity to docetaxel.
miR-139-5p suppresses cancer cell migration and invasion through targeting ZEB1 and ZEB2 in GBM.
MiR-139-5p/SLC7A11 inhibits the proliferation, invasion and metastasis of pancreatic carcinoma via PI3K/Akt signaling pathway.
miR-146a promoted breast cancer proliferation and invasion by regulating NM23-H1.
miR-195 is a key negative regulator of hepatocellular carcinoma metastasis by targeting FGF2 and VEGFA.
miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5.
MiR-198 represses tumor growth and metastasis in colorectal cancer by targeting fucosyl transferase 8.
miR-215 promotes malignant progression of gastric cancer by targeting RUNX1.
MiR-216b inhibits gastric cancer proliferation and migration by targeting PARK7.
miR-24-3p/KLF8 Signaling Axis Contributes to LUAD Metastasis by Regulating EMT.
MiR-29c suppresses invasion and metastasis by targeting TIAM1 in nasopharyngeal carcinoma.
MiR-346 promotes HCC progression by suppressing Breast cancer metastasis suppressor 1 expression.
miR-346 promotes migration and invasion of nasopharyngeal carcinoma cells via targeting BRMS1.
MiR-376a suppresses the proliferation and invasion of non-small-cell lung cancer by targeting c-Myc.
miR-424-5p Promotes Anoikis Resistance and Lung Metastasis by Inactivating Hippo Signaling in Thyroid Cancer.
MiR-501-5p acts as an energetic regulator in head and neck squamous cell carcinoma cells growth and aggressiveness via reducing CLCA4.
miR-520b Inhibits IGF-1R to Increase Doxorubicin Sensitivity and Promote Cell Apoptosis in Breast Cancer.
miR-590-3p suppresses cancer cell migration, invasion and epithelial-mesenchymal transition in glioblastoma multiforme by targeting ZEB1 and ZEB2.
miR-615-3p promotes the epithelial-mesenchymal transition and metastasis of breast cancer by targeting PICK1/TGFBRI axis.
MiR-761 Promotes Progression and Metastasis of Non-Small Cell Lung Cancer by Targeting ING4 and TIMP2.
MiR-9-5p promotes cell growth and metastasis in non-small cell lung cancer through the repression of TGFBR2.
miR?485?5p inhibits bladder cancer metastasis by targeting HMGA2.
miRNA-487a Promotes Proliferation and Metastasis in Hepatocellular Carcinoma.
Mitotic quiescence, but not unique "stemness," marks the phenotype of bone metastasis-initiating cells in prostate cancer.
Monitoring luciferase-labeled cancer cell growth and metastasis in different in vivo models.
Monitoring of prostate cancer growth and metastasis using a PSA luciferase report plasmid in a mouse model.
Monitoring the dynamics of clonal tumour evolution in vivo using secreted luciferases.
Murine tyrosinase expressed by a T7 vector in bone marrow-derived dendritic progenitors effectively prevents and eradicates melanoma tumors in mice.
Myeloid expression of adenosine A2A receptor suppresses T and NK cell responses in the solid tumor microenvironment.
Near infrared photoimmunotherapy prevents lung cancer metastases in a murine model.
Negative feedback between TAp63 and Mir-133b mediates colorectal cancer suppression.
Novel mouse mammary cell lines for in vivo bioluminescence imaging (BLI) of bone metastasis.
Organ-selective chemoresistance in metastasis from human breast cancer cells: inhibition of apoptosis, genetic variability and microenvironment at the metastatic focus.
Overexpression of miR-191 Predicts Poor Prognosis and Promotes Proliferation and Invasion in Esophageal Squamous Cell Carcinoma.
Peritoneal Metastatic Cancer Stem Cells of Gastric Cancer with Partial Mesenchymal-Epithelial Transition and Enhanced Invasiveness in an Intraperitoneal Transplantation Model.
Piceatannol inhibits migration and invasion of prostate cancer cells: possible mediation by decreased interleukin-6 signaling.
PO-16 - ASK1 regulates tumor lung metastasis and platelet functions.
PRDM16 functions as a suppressor of lung adenocarcinoma metastasis.
Prevention of pulmonary metastasis from subcutaneous tumors by binary system-based sustained delivery of catalase.
Propofol?induced miR?125a?5p inhibits the proliferation and metastasis of ovarian cancer by suppressing LIN28B.
PTTG1 regulated by miR-146a-3p promotes bladder cancer migration, invasion, metastasis and growth.
Resveratrol attenuates pulmonary embolism associated cardiac injury by suppressing activation of the inflammasome via the MALAT1?miR?22?3p signaling pathway.
Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells.
Selective Imaging of Malignant Ascites in a Mouse Model of Peritoneal Metastasis Using in Vivo Dynamic Nuclear Polarization-Magnetic Resonance Imaging.
Sequential intravenous injection of anionic polymer and cationic lipoplex of siRNA could effectively deliver siRNA to the liver.
SET8 induces epithelial?mesenchymal transition and enhances prostate cancer cell metastasis by cooperating with ZEB1.
Severe pulmonary metastasis in obese and diabetic mice.
Silencing of hsa_circ_0101145 reverses the epithelial-mesenchymal transition in hepatocellular carcinoma via regulation of the miR-548c-3p/LAMC2 axis.
Simultaneous Multi-Organ Metastases from Chemo-Resistant Triple-Negative Breast Cancer Are Prevented by Interfering with WNT-Signaling.
siRNA delivery to lung-metastasized tumor by systemic injection with cationic liposomes.
SKA3, negatively regulated by miR-128-3p, promotes the progression of non-small-cell lung cancer.
sMicroRNA-1290 inhibits cells proliferation and migration by targeting FOXA1 in gastric cancer cells.
SP1-activated long noncoding RNA lncRNA GCMA functions as a competing endogenous RNA to promote tumor metastasis by sponging miR-124 and miR-34a in gastric cancer.
Spontaneous metastases in immunocompetent mice harboring a primary tumor driven by oncogene latent membrane protein 1 from Epstein-Barr virus.
Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome.
Suppress orthotopic colon cancer and its metastasis through exact targeting and highly selective drug release by a smart nanomicelle.
Systemic Delivery of an Oncolytic Adenovirus Expressing Decorin for the Treatment of Breast Cancer Bone Metastases.
Systemic delivery of sticky siRNAs targeting the cell cycle for lung tumor metastasis inhibition.
Targeted gene therapy and in vivo bioluminescent imaging for monitoring postsurgical recurrence and metastasis in mouse models of liver cancer.
TGF-?-induced STAT3 overexpression promotes human head and neck squamous cell carcinoma invasion and metastasis through malat1/miR-30a interactions.
The dietary flavonoid isoliquiritigenin induced apoptosis and suppressed metastasis in melanoma cells: An in vitro and in vivo study.
The oncoprotein HBXIP facilitates metastasis of hepatocellular carcinoma cells by activation of MMP15 expression.
The potential mechanism of miR-130b on promotion of the invasion and metastasis of hepatocellular carcinoma by inhibiting Notch-Dll1.
The tumor-suppressive function of miR-1 by targeting LASP1 and TAGLN2 in esophageal squamous cell carcinoma.
The Usefulness of Bone Biomarkers for Monitoring Treatment Disease: A Comparative Study in Osteolytic and Osteosclerotic Bone Metastasis Models.
The utility of the "Glowing Head" mouse for breast cancer metastasis research.
Therapeutic effect for liver-metastasized tumor by sequential intravenous injection of anionic polymer and cationic lipoplex of siRNA.
Thermostability of firefly luciferases affects efficiency of detection by in vivo bioluminescence.
TR4 nuclear receptor promotes prostate cancer metastasis via upregulation of CCL2/CCR2 signaling.
Treatment of leptomeningeal metastases in a rat model using a recombinant adenovirus containing the HSV-tk gene.
Tumor angiogenesis therapy using targeted delivery of Paclitaxel to the vasculature of breast cancer metastases.
Upregulated circRNA ARHGAP10 Predicts an Unfavorable Prognosis in NSCLC through Regulation of the miR-150-5p/GLUT-1 Axis.
Use of bioluminescent imaging to investigate the role of nuclear factor-kappaBeta in experimental non-small cell lung cancer metastasis.
Use of FVB Myc-CaP cells as an immune competent, androgen receptor positive, mouse model of prostate cancer bone metastasis.
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.
ZNF671 Inhibits the Proliferation and Metastasis of NSCLC via the Wnt/?-Catenin Pathway.
[Bioluminescence imaging evaluation of the inhibitory effect of lidamycin on lung metastasis of human fibrosarcoma in athymic mice].
[Effect of GTPase activating protein Git2 on metastasis in breast cancer].
[Establishment of a pulmonary metastasis model of melanoma with stably expressed hTERT/Luc].
[miR-181a promotes the proliferation and metastasis of osteosarcoma cells by targeting RASSF1A].
[MiR-218 Targeting Bmi-1 Inhibits Proliferation of Acute Promyelocytic Leukemia Cells].
[MiR-4443 promotes migration and invasion of breast cancer cells by inhibiting PEBP1 expression].
Neoplasm Micrometastasis
A bioluminescent mouse model of pancreatic {beta}-cell carcinogenesis.
Establishment of a novel method to evaluate peritoneal microdissemination and therapeutic effect using luciferase assay.
Neutralizing anti-vascular endothelial growth factor antibody inhibits further growth of established prostate cancer and metastases in a pre-clinical model.
Non-invasive detection of a small number of bioluminescent cancer cells in vivo.
Neoplasm, Residual
Fluorescence-guided resection of experimental malignant glioma using cetuximab-IRDye 800CW.
Neoplasms
"Glowing head" mice: a genetic tool enabling reliable preclinical image-based evaluation of cancers in immunocompetent allografts.
-254C>G SNP in the TRPC6 Gene Promoter Influences Its Expression via Interaction with the NF-?B Subunit RELA in Steroid-Resistant Nephrotic Syndrome Children.
?-Catenin Knockdown in Liver Tumor Cells by a Cell Permeable Gamma Guanidine-based Peptide Nucleic Acid.
A 3D Heterotypic Multicellular Tumor Spheroid Assay Platform to Discriminate Drug Effects on Stroma versus Cancer Cells.
A bioluminescent mouse model of pancreatic {beta}-cell carcinogenesis.
A classic cAMP responsive element in the promoter region of the alpha 1-GABAA receptor subunit has non-classic properties.
A combination of IFN-beta and temozolomide in human glioma xenograft models: implication of p53-mediated MGMT downregulation.
A CXCR4 antagonist CTCE-9908 inhibits primary tumor growth and metastasis of breast cancer.
A Deimmunized Bispecific Ligand-Directed Toxin That Shows an Impressive Anti-Pancreatic Cancer Effect in a Systemic Nude Mouse Orthotopic Model.
A dual cancer-specific recombinant adenovirus suppresses the growth of liver cancer cells in vivo and in vitro.
A fiber-modified mesothelin promoter-based conditionally replicating adenovirus for treatment of ovarian cancer.
A functional variant (-1304T>G) in the MKK4 promoter contributes to a decreased risk of lung cancer by increasing the promoter activity.
A FUS-LATS1/2 Axis Inhibits Hepatocellular Carcinoma Progression via Activating Hippo Pathway.
A genetic strategy involving a glycosyltransferase promoter and a lipid translocating enzyme to eliminate cancer cells.
A genetic variation in microRNA target site of ETS2 is associated with clinical outcomes of paclitaxel-cisplatin chemotherapy in non-small cell lung cancer.
A glypican-1-targeted antibody-drug conjugate exhibits potent tumor growth inhibition in glypican-1-positive pancreatic cancer and esophageal squamous cell carcinoma.
A high-throughput assay pipeline for specific targeting of frizzled GPCRs in cancer.
A luciferase lysis assay reveals in vivo malignant cell sensitization by phosphoantigen prodrugs.
A miR-125b/CSF1-CX3CL1/tumor-associated macrophage recruitment axis controls testicular germ cell tumor growth.
A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance.
A molecular mechanism regulating circadian expression of vascular endothelial growth factor in tumor cells.
A mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by Luciferase imaging.
A Multi-Camera System for Bioluminescence Tomography in Preclinical Oncology Research.
A new bioassay using transient transfection for invasion-related gene analysis.
A new cancer cell detection method using an infectivity-enhanced adenoviral vector.
A new liposomal formulation of Gemcitabine is active in an orthotopic mouse model of pancreatic cancer accessible to bioluminescence imaging.
A nicotine-induced positive feedback loop between HIF1A and YAP1 contributes to epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma.
A Novel 3D In Vitro Platform for Pre-Clinical Investigations in Drug Testing, Gene Therapy, and Immuno-oncology.
A Novel Approach for Monitoring TGF-ß Signaling in vivo in Colon Cancer.
A novel bioluminescent tumor model of human renal cancer cell lines: an in vitro and in vivo characterization.
A Novel Isoform of Human LZIP Negatively Regulates the Transactivation of the Glucocorticoid Receptor.
A novel model of intracranial meningioma in mice using luciferase-expressing meningioma cells. Laboratory investigation.
A novel mucosal orthotopic murine model of human papillomavirus-associated genital cancers.
A Novel Oncolytic Chimeric Orthopoxvirus Encoding Luciferase Enables Real-Time View of Colorectal Cancer Cell Infection.
A novel rat lipoxin A4 receptor that is conserved in structure and function.
A Novel Serum Exosomes-Based Biomarker hsa_circ_0002130 Facilitates Osimertinib-Resistance in Non-Small Cell Lung Cancer by Sponging miR-498.
A Novel Small Molecule Targets Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer.
A novel spontaneous hepatocellular carcinoma mouse model for studying T-cell exhaustion in the tumor microenvironment.
A photon counting technique for quantitatively evaluating progression of peritoneal tumor dissemination.
A Pit-1 binding site in the human renin gene promoter stimulates activity in pituitary, placental and juxtaglomerular cells.
A polymorphic minisatellite region of BORIS regulates gene expression and its rare variants correlate with lung cancer susceptibility.
A positive feedback mechanism in the transcriptional activation of Apaf-1 by p53 and the coactivator Zac-1.
A potential role for imaging technology in anticancer efficacy evaluations.
A promoter-driven assay for INSM1-associated signaling pathway in neuroblastoma.
A rapid and quantitative method to detect human circulating tumor cells in a preclinical animal model.
A real time Metridia luciferase based non-invasive reporter assay of mammalian cell viability and cytotoxicity via the ?-actin promoter and enhancer.
A screen for inducers of p21(waf1/cip1) identifies HIF prolyl hydroxylase inhibitors as neuroprotective agents with antitumor properties.
A simple and sensitive method for measuring tumor-specific T cell cytotoxicity.
A simple in vitro tumor chemosensitivity assay based on cell penetrating peptide tagged luciferase.
A single nucleotide polymorphism associated with hepatitis C virus infections located in the distal region of the IL28B promoter influences NF-?B-mediated gene transcription.
A Small Molecule Inhibitor of the ?-Catenin-TCF4 Interaction Suppresses Colorectal Cancer Growth In Vitro and In Vivo.
A specific peptide ligand-modified lipid nanoparticle carrier for the inhibition of tumor metastasis growth.
A specific tRNA half, 5'tiRNA-His-GTG, responds to hypoxia via the HIF1?/ANG axis and promotes colorectal cancer progression by regulating LATS2.
A survivin-mediated oncolytic adenovirus induces non-apoptotic cell death in lung cancer cells and shows antitumoral potential in vivo.
A therapeutic microparticle-based tumor lysate vaccine reduces spontaneous metastases in murine breast cancer.
A Trp53fl/flPtenfl/fl mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection and in vivo bioluminescence imaging.
Abnormal Eating Patterns Cause Circadian Disruption and Promote Alcohol-Associated Colon Carcinogenesis.
Abnormal increase of miR-4262 promotes cell proliferation and migration by targeting large tumor suppressor 1 in gliomas.
Accelerated Tumor Progression in Mice Lacking the ATP Receptor P2X7.
Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline.
Activation of IRF3 contributes to IFN-? and ISG54 expression during the immune responses to B16F10 tumor growth.
Activation of p53 transcriptional activity by 1,10-phenanthroline, a metal chelator and redox sensitive compound.
Activation of peritoneal cells upon in vivo transfection with a recombinant alphavirus expressing GM-CSF.
Activation of PyMT in beta cells induces irreversible hyperplasia, but oncogene-dependent acinar cell carcinomas when activated in pancreatic progenitors.
Activity of a Py-Im Polyamide Targeted to the Estrogen Response Element.
Activity of the human telomerase catalytic subunit (hTERT) gene promoter could be increased by the SV40 enhancer.
Adenosine A1 Receptor Protects Against Cisplatin Ototoxicity by Suppressing the NOX3/STAT1 Inflammatory Pathway in the Cochlea.
Adenoviral targeting of gene expression to tumors.
Adenoviral vector-mediated gene transfer: timing of wild-type p53 gene expression in vivo and effect of tumor transduction on survival in a rat glioma brachytherapy model.
Adenoviral vectors coated with PAMAM dendrimer conjugates allow CAR independent virus uptake and targeting to the EGF receptor.
Adenovirus HSV-TK construct with thyroid-specific promoter: enhancement of activity and specificity with histone deacetylase inhibitors and agents modulating the camp pathway.
Adenovirus replication-competent vectors (KD1, KD3) complement the cytotoxicity and transgene expression from replication-defective vectors (Ad-GFP, Ad-Luc).
Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter.
Adenovirus vector covalently conjugated to polyethylene glycol with a cancer-specific promoter suppresses the tumor growth through systemic administration.
Adenovirus-mediated hypoxia-targeted gene therapy using HSV thymidine kinase and bacterial nitroreductase prodrug-activating genes in vitro and in vivo.
Adjuvant Trametinib Delays the Outgrowth of Occult Pancreatic Cancer in a Mouse Model of Patient-Derived Liver Metastasis.
Advanced two-step transcriptional amplification as a novel method for cancer-specific gene expression and imaging.
Aerosol-delivered programmed cell death 4 enhanced apoptosis, controlled cell cycle and suppressed AP-1 activity in the lungs of AP-1 luciferase reporter mice.
Affordable luciferase reporter assay for cell-based high-throughput screening.
ALKAL1 gene silencing prevents colorectal cancer progression via suppressing Sonic Hedgehog (SHH) signaling pathway.
Allelic mutations in noncoding genomic sequences construct novel transcription factor binding sites that promote gene overexpression.
ALX4, an epigenetically down regulated tumor suppressor, inhibits breast cancer progression by interfering Wnt/?-catenin pathway.
Aminophenols increase proliferation of thyroid tumor cells by inducing the transcription factor activity of estrogen receptor ?.
Amniotic epithelial cells reverse abnormal vascular structure and function in endometrial carcinoma.
Amplification of transgene expression in vitro and in vivo using a novel inhibitor of histone deacetylase.
An advanced generation of adenoviral vectors selectively enhances gene transfer for ovarian cancer gene therapy approaches.
An anti-tumor role for cGMP-dependent protein kinase.
An aqueous extract of the popular Chinese nutraceutical Kwei Ling Ko (Tortoise shell-Rhizome jelly) activates the PPARgamma pathway and down-regulates the NFkappaB activity.
An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor.
An inducible 50-kilodalton NF kappa B-like protein and a constitutive protein both bind the acute-phase response element of the angiotensinogen gene.
An orthotopic implantation mouse model of human malignant pleural mesothelioma for in vivo photon counting analysis and evaluation of the effect of S-1 therapy.
An orthotopic mouse model for chondrosarcoma of bone provides an in vivo tool for drug testing.
Analyses of BMAL1 and PER2 Oscillations in a Model of Breast Cancer Progression Reveal Changes With Malignancy.
Analysis of the AHR gene proximal promoter GGGGC-repeat polymorphism in lung, breast, and colon cancer.
Androgen receptor is causally involved in the homeostasis of the human prostate endothelial cell.
Angiotensin II promotes primary tumor growth and metastasis formation of murine TNBC 4T1 cells through the fibroblasts around cancer cells.
Animal models of bone metastasis.
Annexin 6 interacts with p65 and stimulates NF-?B activity and catabolic events in articular chondrocytes.
Annulohpoxylotol A and B, new sesquiterpenoids from the endophytic fungus Annulohypoxylon truncatum, are natural NF-?B inhibitors.
Anti-androgenic activity of hydroxyxanthones in prostate cancer LNCaP cells.
Anti-arthritic effects of Ephedra sinica STAPF herb-acupuncture: inhibition of lipopolysaccharide-induced inflammation and adjuvant-induced polyarthritis.
Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia.
Anti-H1N1 virus, cytotoxic and Nrf2 activation activities of chemical constituents from Scutellaria baicalensis.
Anti-Inflammatory Activity of Chemical Constituents Isolated from the Willow Bracket Medicinal Mushroom Phellinus igniarius (Agaricomycetes).
Anti-PD-L1 antibody direct activation of macrophages contributes to a radiation-induced abscopal response in glioblastoma.
Anti-prostate cancer activity of 8-hydroxyquinoline-2-carboxaldehyde-thiosemicarbazide copper complexes in vivo by bioluminescence imaging.
Anti-tumour activity of oncolytic Western Reserve vaccinia viruses in canine tumour cell lines, xenografts, and fresh tumour biopsies.
Anti-VCAM-1 and Anti-IL4R? Aptamer-Conjugated Super Paramagnetic Iron Oxide Nanoparticles for Enhanced Breast Cancer Diagnosis and Therapy.
Antibody targeting of the insulin-like growth factor I receptor enhances the anti-tumor response of multiple myeloma to chemotherapy through inhibition of tumor proliferation and angiogenesis.
Anticancer effects of miR-124 delivered by BM-MSC derived exosomes on cell proliferation, epithelial mesenchymal transition, and chemotherapy sensitivity of pancreatic cancer cells.
Anticancer effects of tanshinone I in human non-small cell lung cancer.
Antisense imaging of gene expression in the brain in vivo.
Antitumor activity of a novel antisense oligonucleotide against Akt1.
Antitumor effect of a dual cancer-specific oncolytic adenovirus on prostate cancer PC-3 cells.
Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis.
Antitumor effects of dammarane-type saponins from steamed Notoginseng.
Antitumor mechanism of MAP30 in bladder cancer T24 cells, and its potential toxic effects in mice.
Application of biodegradable dendrigraft poly-l-lysine to a small interfering RNA delivery system.
Array of Biodegradable Microraftsfor Isolation and Implantation of Living, Adherent Cells.
ASCL2 expression contributes to gastric tumor migration and invasion by downregulating miR223 and inducing EMT.
Assessment of melanoma extent and melanoma metastases invasion using electron paramagnetic resonance and bioluminescence imaging.
Association of TNP2 gene polymorphisms of the bta-miR-154 target site with the semen quality traits of Chinese Holstein bulls.
Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo.
Aurora Kinase A is a Biomarker for Bladder Cancer Detection and Contributes to its Aggressive Behavior.
Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NF?B activation in the tumor stromal microenvironment.
Avenanthramides, polyphenols from oats, exhibit anti-inflammatory and anti-itch activity.
B7-H6 as an efficient target for T cell-induced cytotoxicity in haematologic malignant cells.
Benzochromenones from the marine crinoid Comantheria rotula inhibit hypoxia-inducible factor-1 (HIF-1) in cell-based reporter assays and differentially suppress the growth of certain tumor cell lines.
Benzylamine and Thenylamine Derived Drugs Induce Apoptosis and Reduce Proliferation, Migration and Metastasis Formation in Melanoma Cells.
BGN and COL11A1 Regulatory Network Analysis in Colorectal Cancer (CRC) Reveals That BGN Influences CRC Cell Biological Functions and Interacts with miR-6828-5p.
Bifunctional antibody-Renilla luciferase fusion protein for in vivo optical detection of tumors.
Biodegradable calcium phosphate nanoparticle with lipid coating for systemic siRNA delivery.
Biodistribution and Safety Assessment of Bladder Cancer Specific Recombinant Oncolytic Adenovirus in Subcutaneous Xenografts Tumor Model in Nude Mice.
Biological assessment of triazine dendrimer: toxicological profiles, solution behavior, biodistribution, drug release and efficacy in a PEGylated, paclitaxel construct.
Bioluminescence Imaging of Adoptively Transferred Lymphocytes During Allogeneic Tumor Rejection.
Bioluminescence Imaging of an Immunocompetent Animal Model for Glioblastoma.
Bioluminescence imaging of the response of rat gliosarcoma to ALA-PpIX-mediated photodynamic therapy.
Bioluminescence imaging reveals inhibition of tumor cell proliferation by Alzheimer's amyloid beta protein.
Bioluminescence Imaging-Based Assessment of the Anti-Triple-Negative Breast Cancer and NF-Kappa B Pathway Inhibition Activity of Britanin.
Bioluminescence in drug development for cancer: Shedding light on therapeutic efficacy.
Bioluminescence technology for imaging cell proliferation.
Bioluminescent approaches for measuring tumor growth in a mouse model of neurofibromatosis.
Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivo detection of mammary tumors and multiple metastases in immune deficient mice.
Bioluminescent imaging (BLI) to improve and refine traditional murine models of tumor growth and metastasis.
Bioluminescent imaging of hepatocellular carcinoma in live mice.
Bioluminescent imaging study: FAK inhibitor, PF-562,271, preclinical study in PC3M-luc-C6 local implant and metastasis xenograft models.
Bioluminescent orthotopic model of pancreatic cancer progression.
Bioreducible Fluorinated Peptide Dendrimers Capable of Circumventing Various Physiological Barriers for Highly Efficient and Safe Gene Delivery.
Bioresponsive Deciduous-Charge Amphiphiles for Liposomal Delivery of DNA and siRNA.
Biotinylated Bioluminescent Probe for Long Lasting Targeted in Vivo Imaging of Xenografted Brain Tumors in Mice.
Bispecific anti-CD3 x anti-HER2 antibody mediates T cell cytolytic activity to HER2-positive colorectal cancer in vitro and in vivo.
Bispecific anti-CD3 x anti-B7-H3 antibody mediates T cell cytotoxic ability to human melanoma in vitro and in vivo.
Blocking MIR155HG/miR-155 axis inhibits mesenchymal transition in glioma.
BMI1 polycomb group protein acts as a master switch for growth and death of tumor cells: regulates TCF4-transcriptional factor-induced BCL2 signaling.
Bortezomib-inducible long non-coding RNA myocardial infarction associated transcript is an oncogene in multiple myeloma that suppresses miR-29b.
BRCA1 and p53 regulate critical prostate cancer pathways.
BRCA1 regulation on ?-hCG: a mechanism for tumorigenicity in BRCA1 defective breast cancer.
Breast cancer stem-like cells are sensitized to tamoxifen induction of self-renewal inhibition with enforced Let-7c dependent on Wnt blocking.
Breast tumor cell hybrids form spontaneously in vivo and contribute to breast tumor metastases.
C-Cbl negatively regulates TRAF6-mediated NF-?B activation by promoting K48-linked polyubiquitination of TRAF6.
C/EBP? promotes angiogenesis through secretion of IL-6, which is inhibited by genistein, in EGFRvIII-positive glioblastoma.
C3-Luc Cells Are an Excellent Model for Evaluation of Cellular Immunity following HPV16L1 Vaccination.
Calcineurin/nuclear factors of activated T cells (NFAT)-activating and immunoreceptor tyrosine-based activation motif (ITAM)-containing protein (CNAIP), a novel ITAM-containing protein that activates the calcineurin/NFAT-signaling pathway.
Cancer specificity of promoters of the genes involved in cell proliferation control.
Cancer-derived exosomal miR-138-5p modulates polarization of tumor-associated macrophages through inhibition of KDM6B.
Cancer-specific killing by the CD suicide gene using the human telomerase reverse transcriptase promoter.
Cancer-testis Specific Gene OIP5: A Downstream Gene of E2F1 that Promotes Tumorigenesis and Metastasis in Glioblastoma by Stabilizing E2F1 Signalling.
Canine prostatic cancer cell line (LuMa) with osteoblastic bone metastasis.
CanScript, an 18-Base pair DNA sequence, boosts tumor cell-specific promoter activity implications for targeted gene therapy.
CAPS1 Suppresses Tumorigenesis in Cholangiocarcinoma.
Cationic nanoparticles disrupt cellular signaling in a cholesterol dependent manner.
Cationic versus Neutral Microbubbles for Ultrasound-mediated Gene Delivery in Cancer.
Cationized catalase-loaded hydrogel for growth inhibition of peritoneally disseminated tumor cells.
CCR7 regulates B16 murine melanoma cell tumorigenesis in skin.
CD44 expression level and isoform contributes to pancreatic cancer cell plasticity, invasiveness and response to therapy.
CDC5L Promotes hTERT Expression and Colorectal Tumor Growth.
Cell penetrating thiazole peptides inhibit c-MYC expression via site-specific targeting of c-MYC G-quadruplex.
Cell-based bioluminescence screening assays.
Cell-based high-throughput screens for the discovery of chemotherapeutic agents.
Cell-Selective Messenger RNA Delivery and CRISPR/Cas9 Genome Editing by Modulating the Interface of Phenylboronic Acid-Derived Lipid Nanoparticles and Cellular Surface Sialic Acid.
Cellular MRI Reveals Altered Brain Arrest of Genetically Engineered Metastatic Breast Cancer Cells.
Central memory phenotype drives success of checkpoint inhibition in combination with CAR T cells.
Changing electrode orientation, but not pulse polarity, increases the efficacy of gene electrotransfer to tumors in vivo.
Characterisation of systemic dissemination of nonreplicating adenoviral vectors from tumours in local gene delivery.
Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment.
Characterization of a new class of selective nonsteroidal progesterone receptor agonists.
Characterization of a novel mutation V136L in bone morphogenetic protein 15 identified in a woman affected by POI.
Characterization of cis-regulatory elements of the vascular endothelial growth inhibitor gene promoter.
Characterization of Glyceollins as Novel Aryl Hydrocarbon Receptor Ligands and Their Role in Cell Migration.
Characterization of Infectivity of Knob-Modified Adenoviral Vectors in Glioma.
Characterization of long-circulating cationic nanoparticle formulations consisting of a two-stage PEGylation step for the delivery of siRNA in a breast cancer tumor model.
Characterization of multiple promoters directing tissue-specific expression of the human gonadotropin-releasing hormone gene.
Characterization of the promoter for the alpha3 integrin gene in various tumor cell lines: Roles of the Ets- and Sp-family of transcription factors.
Characterization of the Therapeutic Effects of Novel Chimeric Antigen Receptor T Cells Targeting CD38 on Multiple Myeloma.
Characterization of two mouse models of metastatic pheochromocytoma using bioluminescence imaging.
Chemical Constituents Identified from Fruit Body of Cordyceps bassiana and Their Anti-Inflammatory Activity.
Chemotherapeutic Agents Up-regulate the Cytomegalovirus Promoter: Implications for Bioluminescence Imaging of Tumor Response to Therapy.
Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells.
Chlorotoxin fusion protein regulates miR-374a and TNFAIP8 expression and inhibits glioma cell proliferation and promotes apoptosis.
Circadian oscillations persist in low malignancy breast cancer cells.
CircDUSP16 promotes the tumorigenesis and invasion of gastric cancer by sponging miR-145-5p.
CircGCN1L1 promotes synoviocyte proliferation and chondrocyte apoptosis by targeting miR-330-3p and TNF-? in TMJ osteoarthritis.
CircRNA8924 Promotes Cervical Cancer Cell Proliferation, Migration and Invasion by Competitively Binding to MiR-518d-5p /519-5p Family and Modulating the Expression of CBX8.
Circular RNA GLI2 promotes osteosarcoma cell proliferation, migration, and invasion by targeting miR-125b-5p.
Circular RNA has_circ_0000527 participates in proliferation, invasion and migration of retinoblastoma cells via miR-646/BCL-2 axis.
Circular RNA hsa-circ-000881 suppresses the progression of lung adenocarcinoma in vitro via a miR-665/PRICKLE2 axis.
Circular RNA_PDHX Promotes the Proliferation and Invasion of Prostate Cancer by Sponging MiR-378a-3p.
Circulating exosomal circFoxp1 confers cisplatin resistance in epithelial ovarian cancer cells.
Circ_0000003 promotes the proliferation and metastasis of non-small cell lung cancer cells via miR-338-3p/insulin receptor substrate 2.
Circ_0027599/PHDLA1 suppresses gastric cancer progression by sponging miR-101-3p.1.
circ_0044516 functions in the progression of gastric cancer by modulating MicroRNA-149-5p/HuR axis.
Circ_KATNAL1 regulates prostate cancer cell growth and invasion through miR-145-3p/WISP1 pathway.
Cloning and characterization of the human BAG-1 gene promoter: upregulation by tumor-derived p53 mutants.
Cloning and characterization of the human heparanase-1 (HPR1) gene promoter: role of GA-binding protein and Sp1 in regulating HPR1 basal promoter activity.
Cloning of mouse telomerase reverse transcriptase gene promoter and identification of proximal core promoter sequences essential for the expression of transgenes in cancer cells.
Clotrimazole ameliorates intestinal inflammation and abnormal angiogenesis by inhibiting interleukin-8 expression through a nuclear factor-kappaB-dependent manner.
CNCDatabase: a database of non-coding cancer drivers.
Co-expressing LRP6 With Anti-CD19 CAR-T Cells for Improved Therapeutic Effect Against B-ALL.
Co-polymer of histidine and lysine markedly enhances transfection efficiency of liposomes.
Co-Targeting Prostate Cancer Epithelium and Bone Stroma by Human Osteonectin-Promoter-Mediated Suicide Gene Therapy Effectively Inhibits Androgen-Independent Prostate Cancer Growth.
Codon-Optimized Luciola italica Luciferase Variants for Mammalian Gene Expression in Culture and In Vivo.
Combination of Nanoparticle-Delivered siRNA for Astrocyte Elevated Gene-1 (AEG-1) and All-trans Retinoic Acid (ATRA): An Effective Therapeutic Strategy for Hepatocellular Carcinoma (HCC).
Combination of Radiofrequency Ablation and Glycated Chitosan as Treatment on a Syngeneic Breast Tumor Model.
Combination therapy of conditionally replicating adenovirus and histone deacetylase inhibitors.
Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma.
Combinatorial optimization of PEG architecture and hydrophobic content improves ternary siRNA polyplex stability, pharmacokinetics, and potency in vivo.
Combined Chemisorption and Complexation Generate siRNA Nanocarriers with Biophysics Optimized for Efficient Gene Knockdown and Air-Blood Barrier Crossing.
Combined NK Cell Therapy and Radiation Therapy Exhibit Long-Term Therapeutic and Antimetastatic Effects in a Human Triple Negative Breast Cancer Model.
Combined noninvasive imaging and luminometric quantification of luciferase-labeled human prostate tumors and metastases.
Comparison of noninvasive fluorescent and bioluminescent small animal optical imaging.
Complementarity of Variable-magnification and Spectral-separation Fluorescence Imaging Systems for Noninvasive Detection of Metastasis and Intravital Detection of Single Cancer Cells in Mouse Models.
CONSORT: Sam68 Is Directly Regulated by MiR-204 and Promotes the Self-Renewal Potential of Breast Cancer Cells by Activating the Wnt/Beta-Catenin Signaling Pathway.
Constraints to counting bioluminescence producing cells by a commonly used transgene promoter and its implications for experimental design.
Construction and validation of improved triple fusion reporter gene vectors for molecular imaging of living subjects.
Construction of a star-shaped copolymer as a vector for FGF receptor-mediated gene delivery in vitro and in vivo.
Construction of a tumor-specific bioluminescent eukaryotic expression vector and analysis of its expression in vitro and in vivo.
Construction of X-ray-inducible promoters through cis-acting element elongation and error-prone polymerase chain reaction.
Continuous delivery of D-luciferin by implanted micro-osmotic pumps enables true real-time bioluminescence imaging of luciferase activity in vivo.
Control of cyclosporine A-induced tumor progression using 15-deoxyspergualin for rat cardiac transplantation.
Cooperation between AP1 and PEA3 sites within the progression elevated gene-3 (PEG-3) promoter regulate basal and differential expression of PEG-3 during progression of the oncogenic phenotype in transformed rat embryo cells.
Core - shell upconversion nanoparticle - semiconductor heterostructures for photodynamic therapy.
Cox-2 gene expression in chemically induced skin papillomas cannot predict subsequent tumor fate.
COX-2 involvement in breast cancer metastasis to bone.
CPEB1 mediates hepatocellular carcinoma cancer stemness and chemoresistance.
CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression.
Cryoablation and Meriva have strong therapeutic effect on triple-negative breast cancer.
Cucurbit [7] uril encapsulated cisplatin overcomes resistance to cisplatin induced by Rab25 overexpression in an intraperitoneal ovarian cancer model.
CXCL16 signals via Gi, phosphatidylinositol 3-kinase, Akt, I kappa B kinase, and nuclear factor-kappa B and induces cell-cell adhesion and aortic smooth muscle cell proliferation.
CXCR1 knockdown improves the sensitivity of osteosarcoma to cisplatin.
Cytokine inhibition of the hepatitis B virus core promoter.
Cytokine-induced killer cells efficiently kill stem-like cancer cells of nasopharyngeal carcinoma via the NKG2D-ligands recognition.
Cytokine-mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein 1 and nuclear factor kappaB-binding sites.
Cytotoxicity of replication-competent adenoviruses powered by an exogenous regulatory region is not linearly correlated with the viral infectivity/gene expression or with the E1A-activating ability but is associated with the p53 genotypes.
Daily timed meals dissociate circadian rhythms in hepatoma and healthy host liver.
De-targeting by miR-143 decreases unwanted transgene expression in non-tumorigenic cells.
Decreased miR-124 contributes to the epithelial-mesenchymal transition phenotype formation of lung adenocarcinoma cells via targeting enhancer of zeste homolog 2.
Delimiting Allelic Imbalance of TYMS by Allele-Specific Analysis.
Delivery of small interfering RNA with a synthetic collagen poly(Pro-Hyp-Gly) for gene silencing in vitro and in vivo.
Deoxybenzoins are novel potent selective estrogen receptor modulators.
Detection of Brain Tumors and Systemic Metastases Using NanoLuc and Fluc for Dual Reporter Imaging.
Detection of Extracellular ATP in the Tumor Microenvironment, Using the pmeLUC Biosensor.
Determination of androgen bioactivity in human serum samples using a recombinant cell based in vitro bioassay.
Development of a Bioluminescent BRCA1-Deficient Xenograft Model of Disseminated, High-Grade Serous Ovarian Cancer.
Development of a Conditional Bioluminescent Transplant Model for TPM3-ALK-Induced Tumorigenesis as a Tool to Validate ALK-Dependent Cancer Targeted Therapy.
Development of a high-throughput screening cancer cell-based luciferase refolding assay for identifying Hsp90 inhibitors.
Development of a luciferase reporter Jurkat cell line under the control of endogenous interleukin-2 promoter.
Development of a syngeneic mouse model of epithelial ovarian cancer.
Development of an Image-Guided Orthotopic Xenograft Mouse Model of Endometrial Cancer with Controllable Estrogen Exposure.
Development of an Orthotopic Intrasplenic Xenograft Mouse Model of Canine Histiocytic Sarcoma and Its Use in Evaluating the Efficacy of Treatment with Dasatinib.
Development of an orthotopic syngeneic murine model of colorectal cancer for use in translational research.
Development of artificial chimerical gene regulatory elements specific for cancer gene therapy.
Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts.
Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies.
Development of transferrin-polycation/DNA based vectors for gene delivery to melanoma cells.
Development of two androgen receptor assays using adenoviral transduction of MMTV-luc reporter and/or hAR for endocrine screening.
Dexamethasone-induced inhibition of miR-132 via methylation promotes TGF-?-driven progression of pancreatic cancer.
Diacetoxyscirpenol as a new anticancer agent to target hypoxia-inducible factor 1.
Diagnostic and therapeutic evaluation of 111In-vinorelbine-liposomes in a human colorectal carcinoma HT-29/luc-bearing animal model.
Diarylheptanoid Hirsutenone Attenuates Osteoclastogenesis by Suppressing IFN? and NF-?B Signaling in Th1 and Preosteoclastic Cells.
Different effect of paclitaxel on primary tumor mass, tumor cell contents, and metastases for four experimental human prostate tumors expressing luciferase.
Different transcriptional activity and in vitro TNF-alpha production in psoriasis patients carrying the TNF-alpha 238A promoter polymorphism.
Differential effects of flavonoid compounds on tumor promoter-induced activation of the human CYP1A2 enhancer.
Differential localization and activity of the A- and B-forms of the human progesterone receptor using green fluorescent protein chimeras.
Direct activation of oestrogen receptor-alpha by interleukin-6 in primary cultures of breast cancer epithelial cells.
Direct intratumoral gene transfer of the herpes simplex virus thymidine kinase gene with DNA-liposome complexes: growth inhibition of tumors and lack of localization in normal tissues.
DNA-mediated gene transfer into adult rat hepatocytes in primary culture.
DNAH17-AS1 promotes pancreatic carcinoma by increasing PPME1 expression via inhibition of miR-432-5p.
Docetaxel induced-JNK2/PHD1 signaling pathway increases degradation of HIF-1? and causes cancer cell death under hypoxia.
Dominant negative p38 mitogen-activated protein kinase expression inhibits NF-kappaB activation in AR42J cells.
Dominant-negative activator protein 1 (TAM67) targets cyclooxygenase-2 and osteopontin under conditions in which it specifically inhibits tumorigenesis.
Down-regulation of microRNA-34a-5p promotes trophoblast cell migration and invasion via targetting Smad4.
Downregulation of FOXO6 in breast cancer promotes epithelial-mesenchymal transition and facilitates migration and proliferation of cancer cells.
Downregulation of long noncoding RNA TUSC7 promoted cell growth, invasion and migration through sponging with miR-616-5p/GSK3? pathway in ovarian cancer.
Downregulation of miR-542-3p promotes cancer metastasis through activating TGF-?/Smad signaling in hepatocellular carcinoma.
Drug-inducible remote control of gene expression by probiotic Escherichia coli Nissle 1917 in intestine, tumor and gall bladder of mice.
Drugs which inhibit osteoclast function suppress tumor growth through calcium reduction in bone.
Dual bioluminescence and near-infrared fluorescence monitoring to evaluate spherical nucleic acid nanoconjugate activity in vivo.
Dynamics of tumor hypoxia in response to patupilone and ionizing radiation.
Dysregulation of the miR-325-3p/DPAGT1 axis supports HBV-positive HCC chemoresistance.
Early tumor detection afforded by in vivo imaging of near-infrared II fluorescence.
Effect of antiangiogenic therapy on luciferase activity in a cytomegalovirus- or HSP70-promoter-transfected M21 tumor model.
Effect of apple extracts on NF-kappaB activation in human umbilical vein endothelial cells.
Effect of brain- and tumor-derived connective tissue growth factor on glioma invasion.
Effect of glycolysis inhibition by miR-448 on glioma radiosensitivity.
Effect of promoter and intron 2 polymorphisms on murine lung K-ras gene expression.
Effective delivery of DNA into tumor cells and tissues by electroporation of polymer-DNA complex.
Effects of insulin on in vitro vascular cell adhesion molecule-1 expression and in vivo soluble VCAM-1 release.
Effects of PEGylated paclitaxel nanocrystals on breast cancer and its lung metastasis.
Effects of pyrrolidine dithiocarbamate on proliferation and nuclear factor-?B activity in autosomal dominant polycystic kidney disease cells.
Effects of rate, volume, and dose of intratumoral infusion on virus dissemination in local gene delivery.
Effects of Sucrose Ester Structures on Liposome-Mediated Gene Delivery.
Effects of VCP979 Novel p38 Mitogen Activated Protein Kinase Inhibitor on Progression of Pancreatic Cancer in Mouse Model with Diabetic Conditions.
Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM.
Efficacy of transfection rates on head and neck squamous cell cancer by a novel adenovirus: an in vivo and in vitro study.
Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo.
Efficient DNA electrotransfer into tumors.
Efficient gene transfer into mammalian cells using fusogenic liposome.
EGFR Targeting and Shielding of pDNA Lipopolyplexes via Bivalent Attachment of a Sequence-Defined PEG Agent.
Electrodelivery of drugs into cancer cells in the presence of poloxamer 188.
Electroporation-enhanced gene delivery in mammary tumors.
Elevated mPer1 gene expression in tumor stroma imaged through bioluminescence.
Elevated NIBP/TRAPPC9 mediates tumorigenesis of cancer cells through NF?B signaling.
Elevation of liver endoplasmic reticulum stress in a modified choline-deficient l-amino acid-defined diet-fed non-alcoholic steatohepatitis mouse model.
Endothelium-specific expression of an E-selectin promoter recombinant adenoviral vector.
Engineered immune cells as highly sensitive cancer diagnostics.
Enhanced anti-tumor efficacy and safety profile of tumor microenvironment-responsive oncolytic adenovirus nanocomplex by systemic administration.
Enhanced antitumor effect and reduced vector dissemination with fiber-modified adenovirus vectors expressing herpes simplex virus thymidine kinase.
Enhanced growth inhibition of metastatic lung tumors by intravenous injection of ATRA-cationic liposome/IL-12 pDNA complexes in mice.
Enhanced noninvasive imaging of oncology models using the NIS reporter gene and bioluminescence imaging.
Enhanced transgene expression and effective in vivo antitumor immune responses initiated by dendritic progenitors transfected with a nonviral T7 vector expressing a model tumor antigen.
Enhancement of gene expression under hypoxic conditions using fragments of the human vascular endothelial growth factor and the erythropoietin genes.
Entry Tropism of BK and Merkel Cell Polyomaviruses in Cell Culture.
EphB4 Promotes Site-Specific Metastatic Tumor Cell Dissemination by Interacting with Endothelial Cell-Expressed EphrinB2.
Epigenetic Silencing of miR-203 Upregulates SNAI2 and Contributes to the Invasiveness of Malignant Breast Cancer Cells.
Epigenetic silencing of miR-338 facilitates glioblastoma progression by de-repressing the pyruvate kinase M2-?-catenin axis.
Epimedin C Promotes Vascularization during BMP2-Induced Osteogenesis and Tumor-Associated Angiogenesis.
Epithelial to mesenchymal transition and cancer stem cell phenotypes leading to liver metastasis are abrogated by the novel TGF?1-targeting peptides P17 and P144.
Epsilon-caprolactone Modified Polyethyleneimine as Efficient Nanocarriers for siRNA Delivery in Vivo.
Epstein-Barr virus encoded miR-BART11 promotes inflammation-induced carcinogenesis by targeting FOXP1.
Epstein-Barr virus-based vector improves the tumor cell killing effect of pituitary tumor in HVJ-liposome-mediated transcriptional targeting suicide gene therapy.
Establishment and characterization of transplantable, luminescence labeled rat renal cell carcinoma cell lines.
Establishment and evaluation of a new highly metastatic tumor cell line 5a-D-Luc-ZsGreen expressing both luciferase and green fluorescent protein.
Establishment and exploitation of hyperdiploid and non-hyperdiploid human myeloma cell lines.
Establishment of a bioluminescent canine B-cell lymphoma xenograft model for monitoring tumor progression and treatment response in preclinical studies.
Establishment of a bioluminescent Renca cell line for renal carcinoma research.
Establishment of a novel method to evaluate peritoneal microdissemination and therapeutic effect using luciferase assay.
Estrogen Receptor Alpha (ER?)-Associated Fibroblasts Promote Cell Growth in Prostate Cancer.
Estrogenic Compounds or Adiponectin Inhibit Cyclic AMP Response to Human Luteinizing Hormone in Mouse Leydig Tumor Cells.
Euodia pasteuriana Methanol Extract Exerts Anti-Inflammatory Effects by Targeting TAK1 in the AP-1 Signaling Pathway.
Evaluation of a CXCR4 antagonist in a xenograft mouse model of inflammatory breast cancer.
Evaluation of bioluminescent imaging for noninvasive monitoring of colorectal cancer progression in the liver and its response to immunogene therapy.
Evaluation of cell-based assays for steroid nuclear receptors delivered by recombinant baculoviruses.
Evaluation of chemical chaperones based on the monitoring of Bip promoter activity and visualization of extracellular vesicles by real-time bioluminescence imaging.
Evaluation of metastatic niches in distant organs after surgical removal of tumor-bearing lymph nodes.
Evaluation of tissue-specific promoters in carcinomas of the cervix uteri.
Evaluation of tumor-specific promoter activities in melanoma.
Excess of a Rassf1-targeting microRNA, miR-193a-3p, perturbs cell division fidelity.
Exosomal transfer of miR?25?3p promotes the proliferation and temozolomide resistance of glioblastoma cells by targeting FBXW7.
Expression and role of oncogenic miRNA-224 in esophageal squamous cell carcinoma.
Expression of dominant negative c-jun inhibits ultraviolet B-induced squamous cell carcinoma number and size in an SKH-1 hairless mouse model.
Expression of tdTomato and luciferase in a murine lung cancer alters the growth and immune microenvironment of the tumor.
Expression profiles of miRNAs in giant cell tumor of bone showed miR-187-5p and miR-1323 can regulate biological functions through inhibiting FRS2.
Extended-release PEG-luciferin allows for long-term imaging of firefly luciferase activity in vivo.
Extracellular ubiquitin promotes hepatoma metastasis by mediating M2 macrophage polarization via the activation of the CXCR4/ERK signaling pathway.
Extracellular vesicles enriched with miR-150 released by macrophages regulates the TP53-IGF-1 axis to alleviate myocardial infarction.
Extracts from Pulsatilla patens target cancer-related signaling pathways in HeLa cells.
Factors regulating pS2-reporter gene expression in MCF-7 breast cancer cell line.
FAPP2 promotes tumor cell growth in human colon cancer through activation of Wnt signaling.
Female pseudohermaphroditism caused by a novel homozygous missense mutation of the GR gene.
Few genes are associated with the capability of pancreatic ductal adenocarcinoma cells to grow in the liver of nude rats.
Fisetin, a dietary flavonoid, induces apoptosis of cancer cells by inhibiting HSF1 activity through blocking its binding to the hsp70 promoter.
Flavoprotein miniSOG Cytotoxisity Can Be Induced By Bioluminescence Resonance Energy Transfer.
Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer.
Forkhead box p3 controls progression of oral lichen planus by regulating microRNA-146a.
FoxM1 is regulated by both HIF-1? and HIF-2? and contributes to gastrointestinal stromal tumor progression.
FOXP3 controls an miR-146/NF?B negative feedback loop that inhibits apoptosis in breast cancer cells.
FOXP3 inhibits NF-?B activity and hence COX2 expression in gastric cancer cells.
Free cationic liposomes inhibit the inflammatory response to cationic lipid-DNA complex injected intravenously and enhance its transfection efficiency.
Fructose-1,6-Bisphosphatase 1 Reduces (18)F FDG Uptake in Hepatocellular Carcinoma.
Functional characterization of BmOVOs in silkworm, Bombyx mori.
Functional implication of TRAIL -716 C/T promoter polymorphism on its in vitro and in vivo expression and the susceptibility to sporadic breast tumor.
Functional Variants at the 11q13 Risk Locus for Breast Cancer Regulate Cyclin D1 Expression through Long-Range Enhancers.
Fusion protein of the hyaluronan binding domain from human TSG-6 with luciferase for assay of hyaluronan.
Gambogic Acid Efficiently Kills Stem-Like Colorectal Cancer Cells by Upregulating ZFP36 Expression.
Gene delivery using liposome technology.
Gene delivery with optimized electroporation parameters shows potential for treatment of gliomas.
Gene expression and antitumor effects following direct interferon (IFN)-gamma gene transfer with naked plasmid DNA and DC-chol liposome complexes in mice.
Gene silencing in primary and metastatic tumors by small interfering RNA delivery in mice: quantitative analysis using melanoma cells expressing firefly and sea pansy luciferases.
Gene therapy of a rat follicular thyroid carcinoma model with adenoviral vectors transducing murine interleukin-12.
Gene therapy of carcinoma using ultrasound-targeted microbubble destruction.
Gene transfer to subdermal tissues via a new gene gun design.
Gene transfer using liposome-complexed adenovirus seems to overcome limitations due to coxsackievirus and adenovirus receptor-deficiency of cancer cells, both in vitro and in vivo.
Gene transfer-mediated intracellular photodynamic therapy.
General Strategy for Bioluminescence Sensing of Peptidase Activity In Vivo Based on Tumor-Targeting Probiotic.
Generation and characterization of orthotopic murine models for endometrial cancer.
Generation of Luciferase-expressing Tumor Cell Lines.
Genetic modification of cancer cells using non-viral, episomal S/MAR vectors for in vivo tumour modelling.
Genetic strategy to decrease complement activation with adenoviral therapies.
Genetic variants in microRNAs predict non-small cell lung cancer prognosis in Chinese female population in a prospective cohort study.
Ginkgolide B enhances gemcitabine sensitivity in pancreatic cancer cell lines via inhibiting PAFR/NF-?B pathway.
GL261 luciferase-expressing cells elicit an anti-tumor immune response: an evaluation of murine glioma models.
Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells.
Glycogen synthase kinase-3 beta regulates Snail and ?-catenin expression during Fas-induced epithelial-mesenchymal transition in gastrointestinal cancer.
Glycosylation profile and biological activity of Remicade® compared with Flixabi® and Remsima®.
Glycyrrhizin Acid and Glycyrrhetinic Acid Modified Polyethyleneimine for Targeted DNA Delivery to Hepatocellular Carcinoma.
Gm6377 suppressed SP 2/0 xenograft tumor by down-regulating Myc transcription.
Gold Nanoparticle-Assisted Virus Formation by Means of the Delivery of an Oncolytic Adenovirus Genome.
Granulin epithelin precursor promotes colorectal carcinogenesis by activating MARK/ERK pathway.
Green tea polyphenols as potent enhancers of glucocorticoid-induced mouse mammary tumor virus gene expression.
Hairpin ribozyme-antisense RNA constructs can act as molecular Lassos.
Heat-directed suicide gene therapy mediated by heat shock protein promoter for gastric cancer.
Herpes simplex virus thymidine kinase-mediated suicide gene therapy using nano/microbubbles and ultrasound.
High-throughput screening identifies aclacinomycin as a radiosensitizer of EGFR-mutant non-small cell lung cancer.
Highly expressed lncRNA FOXD3-AS1 promotes non-small cell lung cancer progression via regulating miR-127-3p/mediator complex subunit 28 axis.
Highly sensitive luciferase reporter assay using a potent destabilization sequence of calpain 3.
HISTONE DEACETYLASE INHIBITION AFFECTS SODIUM IODIDE SYMPORTER (NIS) EXPRESSION AND INDUCES ¹³¹I CYTOTOXICITY IN ANAPLASTIC THYROID CANCER CELLS.
HLF/miR-132/TTK axis regulates cell proliferation, metastasis and radiosensitivity of glioma cells.
Host mediated anti-tumor effect of oncolytic Newcastle disease virus after locoregional application.
How to Select Firefly Luciferin Analogues for In Vivo Imaging.
hsa-miR-20b-5p and hsa-miR-363-3p Affect Expression of PTEN and BIM Tumor Suppressor Genes and Modulate Survival of T-ALL Cells In Vitro.
Hsa-miR-942 fingerprint in colorectal cancer through Wnt signaling pathway.
Hsa_circ_0001869 promotes NSCLC progression via sponging miR-638 and enhancing FOSL2 expression.
hsa_circ_0058357 acts as a ceRNA to promote non?small cell lung cancer progression via the hsa?miR?24?3p/AVL9 axis.
hTERT and BIRC5 gene promoters for cancer gene therapy: A comparative study.
Human antigen-specific regulatory T cells generated by T cell receptor gene transfer.
Human coxsackie adenovirus receptor (CAR) expression in transgenic mouse prostate tumors enhances adenoviral delivery of genes.
Human immunodeficiency virus type 1 protease inhibitors block toll-like receptor 2 (TLR2)- and TLR4-Induced NF-kappaB activation.
Human macrophage inflammatory protein-3alpha/CCL20/LARC/Exodus/SCYA20 is transcriptionally upregulated by tumor necrosis factor-alpha via a non-standard NF-kappaB site.
Human progesterone receptor A and B isoforms in CHO cells. II. Comparison of binding, transactivation and ED50 values of several synthetic (anti)progestagens in vitro in CHO and MCF-7 cells and in vivo in rabbits and rats.
Human Serum Enhances Biomimicry of Engineered Tissue Models of Bone and Cancer.
Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice.
Human-in-mouse modeling of primary head and neck squamous cell carcinoma.
Hyaluronic acid-conjugated lipoplexes for targeted delivery of siRNA in a murine metastatic lung cancer model.
Hyaluronidase and collagenase increase the transfection efficiency of gene electrotransfer in different murine tumors.
Hydrogen peroxide-mediated nuclear factor kappaB activation in both liver and tumor cells during initial stages of hepatic metastasis.
Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing.
Hypoxia-induced cytosine deaminase gene expression for cancer therapy.
Hypoxia-inducible miR-196a modulates glioblastoma cell proliferation and migration through complex regulation of NRAS.
Hypoxia-inhibited miR-338-3p suppresses breast cancer progression by directly targeting ZEB2.
ID1 confers cancer cell chemoresistance through STAT3/ATF6-mediated induction of autophagy.
ID4 Promotes Breast Cancer Chemotherapy Resistance via CBF1-MRP1 Pathway.
Identification and functional characterization of the bovine manganous superoxide dismutase promoter.
Identification and functional characterization of the human glutathione S-transferase P1 gene as a novel transcriptional target of the p53 tumor suppressor gene.
Identification of a Ligand-induced Transient Refractory Period in Nuclear Factor-{kappa}B Signaling.
Identification of a phorbol ester responsive region in the myeloid-specific promoter of the c-fgr proto-oncogene.
Identification of miR-30e* regulation of Bmi1 expression mediated by tumor-associated macrophages in gastrointestinal cancer.
Identification of miRNAs that specifically target tumor suppressive KLF6-FL rather than oncogenic KLF6-SV1 isoform.
Identification of novel Sp1 targets involved in proliferation and cancer by functional genomics.
Identification of Small Molecule Modulators of MicroRNA by Library Screening.
Identification of tissue- and cancer-selective promoters for the introduction of genes into human ovarian cancer cells.
Ikappab kinase-beta (ikkbeta) modulation of epithelial sodium channel activity.
IL-1? and TNF-? regulate mouse amelotin gene transcription in gingival epithelial cells.
ILF2 promotes anchorage independence through direct regulation of PTEN.
Illuminating cancer systems with genetically engineered mouse models and coupled luciferase reporters in vivo.
Imaging Dendrimer-Grafted Graphene Oxide Mediated Anti-miR-21 Delivery With an Activatable Luciferase Reporter.
Imaging immediate-early and strict-late promoter activity during oncolytic herpes simplex virus type 1 infection and replication in tumors.
Imaging luciferase-expressing viruses.
Imaging neural stem cell fate in mouse model of glioma.
Imaging of conditional gene silencing in vivo using a bioluminescence-based method with thermo-inducible microRNAs.
Imaging of Firefly Luciferase Activity under Antiangiogenic Therapy in a Heat Shock Protein 70-Transfected Melanoma Tumor Model.
Imaging of HIF-1-Active Tumor Hypoxia Using a Protein Effectively Delivered to and Specifically Stabilized in HIF-1-Active Tumor Cells.
Imaging of hypoxia-driven gene expression in an orthotopic liver tumor model.
Imaging of light emission from the expression of luciferases in living cells and organisms: a review.
Imaging of luciferase and GFP-transfected human tumours in nude mice.
Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth.
Imbricaric acid and perlatolic acid: multi-targeting anti-inflammatory depsides from Cetrelia monachorum.
Immune evasion by murine melanoma mediated through CC chemokine receptor-10.
Immunomodulation Mediated by Azithromycin in Experimental Periapical Inflammation.
Impact of hydrodynamic injection and phiC31 integrase on tumor latency in a mouse model of MYC-induced hepatocellular carcinoma.
Impact of preimmunization on adenoviral vector expression and toxicity in a subcutaneous mouse cancer model.
Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging.
Implication of KRT16, FAM129A and HKDC1 genes as ATF4 regulated components of the integrated stress response.
Improved dual-luciferase reporter assays for nuclear receptors.
In vitro and in vivo nuclear factor-kappaB inhibitory effects of the cell-penetrating penetratin peptide.
In vitro and in vivo transfection of plasmid DNA in the Dunning prostate tumor R3327-AT1 is enhanced by focused ultrasound.
In vitro effect of focused ultrasound or thermal stress on HSP70 expression and cell viability in three tumor cell lines.
In vitro gene delivery mediated by chitosan. effect of pH, serum, and molecular mass of chitosan on the transfection efficiency.
In Vivo Bioluminescence Imaging of Murine Xenograft Cancer Models with a Red-shifted Thermostable Luciferase.
In vivo bioluminescence imaging of tumor hypoxia dynamics of breast cancer brain metastasis in a mouse model.
In vivo bioluminescent imaging of irradiated orthotopic pancreatic cancer xenografts in nonobese diabetic-severe combined immunodeficient mice: a novel method for targeting and assaying efficacy of ionizing radiation.
In vivo cytotoxicity assay for assessing immunity.
In vivo expression of murine platelet glycoprotein Ibalpha.
In vivo imaging and therapeutic treatments in an orthotopic mouse model of ovarian cancer.
In vivo imaging of adenovirus transduction and enhanced therapeutic efficacy of combination therapy with conditionally replicating adenovirus and adenovirus-p27.
In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation.
In Vivo Imaging of Orthotopic Lung Cancer Models in Mice.
In vivo imaging of retinoic acid receptor activity using a sodium/iodide symporter and luciferase dual imaging reporter gene.
In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice.
In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats.
In Vivo Live Imaging of Oncolytic Mammalian Orthoreovirus Expressing NanoLuc Luciferase in Tumor Xenograft Mice.
In vivo monitoring of antiangiogenic therapy by magnetic resonance and bioluminescence imaging in an M21 tumor model through activation of an hsp70 promoter-luciferase reporter construct.
In vivo monitoring of tumor relapse and metastasis using bioluminescent PC-3M-luc-C6 cells in murine models of human prostate cancer.
In vivo profiling of estrogen receptor/specificity protein-dependent transactivation.
In vivo transfection of melanoma cells by lithotripter shock waves.
In vivo tumor gene delivery using novel peptideticles: pH-responsive and ligand targeted core-shell nanoassembly.
Increased level of extracellular ATP at tumor sites: in vivo imaging with plasma membrane luciferase.
Increased oncolytic efficacy for high-grade gliomas by optimal integration of ionizing radiation into the replicative cycle of HSV-1.
Indexing TNF-alpha gene expression using a gene-targeted reporter cell line.
Induced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer.
Induction of Luciferase Activity under the Control of an hsp70 Promoter Using High-Intensity Focused Ultrasound: Combination of Bioluminescence and MRI Imaging in Three Different Tumour Models.
Induction of the suicide HSV-TK gene by activation of the Egr-1 promoter with radioisotopes.
Inflammation-induced transgene expression in genetically engineered equine mesenchymal stem cells.
Influences of the p53 status on hypoxia-induced gene expression.
Inhibition of glucocorticoid receptor-mediated transcriptional activation by p38 mitogen-activated protein (MAP) kinase.
Inhibition of GTP cyclohydrolase attenuates tumor growth by reducing angiogenesis and M2-like polarization of tumor associated macrophages.
Inhibition of in vivo tumor angiogenesis and growth via systemic delivery of an angiopoietin 2-specific RNA aptamer.
Inhibition of metastatic tumor growth in mouse lung by repeated administration of polyethylene glycol-conjugated catalase: quantitative analysis with firefly luciferase-expressing melanoma cells.
Inhibition of miR30a-3p by sulforaphane enhances gap junction intercellular communication in pancreatic cancer.
Inhibition of NF-kappaB and HIV-1 long terminal repeat transcriptional activation by inducible nitric oxide synthase 2 activity.
Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide.
Inhibition of prostate cancer neovascularization and growth by urokinase-plasminogen activator receptor blockade.
Inhibition of TNF-?-mediated NF-?B Transcriptional Activity in HepG2 Cells by Dammarane-type Saponins from Panax ginseng Leaves.
Inhibition of tumor growth by direct intratumoral gene transfer of herpes simplex virus thymidine kinase gene with DNA-liposome complexes.
Inhibition of tumor growth by DT-A expressed under the control of IGF2 P3 and P4 promoter sequences.
Inhibition of U6 snRNA Transcription by PTEN.
Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response.
Inhibitory effects of ethyl acetate extract of Andrographis paniculata on NF-{kappa}B trans-activation activity and LPS-induced acute inflammation in mice.
Integrated microarray meta-analysis identifies miRNA-27a as an oncogene in ovarian cancer by inhibiting FOXO1.
Integration and long-term expression in xenografted human glioblastoma cells using a plasmid-based transposon system.
Integrin-targeted nanocomplexes for tumour specific delivery and therapy by systemic administration.
Interleukin 6/Wnt interactions in rheumatoid arthritis: interleukin 6 inhibits Wnt signaling in synovial fibroblasts and osteoblasts.
Interleukin-12 gene transfer results in CD8-dependent regression of murine CT26 liver tumors.
Intestinal probiotics E. coli Nissle 1917 as a targeted vehicle for delivery of p53 and Tum-5 to solid tumors for cancer therapy.
Intra-arterial adenoviral mediated tumor transfection in a novel model of cancer gene therapy.
Intraarterial gene delivery in rabbit hepatic tumors: transfection with nonviral vector by using iodized oil emulsion.
Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells.
Intrabodies targeting human papillomavirus 16 E6 and E7 oncoproteins for therapy of established HPV-associated tumors.
Intraperitoneal photodynamic therapy mediated by a fullerene in a mouse model of abdominal dissemination of colon adenocarcinoma.
Intratracheal administration of a nanoparticle-based therapy with the angiotensin II type 2 receptor gene attenuates lung cancer growth.
Intratumoral delivery of bortezomib: impact on survival in an intracranial glioma tumor model.
Intravesically administered antisense oligonucleotides targeting heat-shock protein-27 inhibit the growth of non-muscle-invasive bladder cancer.
Irradiation with ultrasound of low output intensity increased chemosensitivity of subcutaneous solid tumors to an anti-cancer agent.
Isolation, antiproliferation on tumor cell and immunomodulatory activity of BSP-I, a novel bursal peptide from chicken humoral immune system.
Isoliquiritigenin suppresses the proliferation and induced apoptosis via miR-32/LATS2/Wnt in nasopharyngeal carcinoma.
Key promoter elements involved in transcriptional activation of the cancer-related gene coding for S100P calcium-binding protein.
KIF2C exerts an oncogenic role in nonsmall cell lung cancer and is negatively regulated by miR-325-3p.
KLF6 is one transcription factor involved in regulating acid ceramidase gene expression.
Knockdown of EBV-encoded circRNA circRPMS1 suppresses nasopharyngeal carcinoma cell proliferation and metastasis through sponging multiple miRNAs.
Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth.
KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines.
Lac/Tet dual-inducible system functions in mammalian cell lines.
Large T Antigen-Specific Cytotoxic T Cells Protect Against Dendritic Cell Tumors through Perforin-Mediated Mechanisms Independent of CD4 T Cell Help.
Lentiviral-Mediated Overexpression of MicroRNA-141 Promotes Cell Proliferation and Inhibits Apoptosis in Human Esophageal Squamous Cell Carcinoma.
Lentiviruses with trastuzumab bound to their envelopes can target and kill prostate cancer cells.
Leptin-elicited miRNA-342-3p potentiates gemcitabine resistance in pancreatic ductal adenocarcinoma.
Ligands located within a cholesterol domain enhance gene delivery to the target tissue.
LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer.
LINC00511 facilitates Temozolomide resistance of glioblastoma cells via sponging miR-126-5p and activating Wnt/?-catenin signaling.
Lithotripter shock waves with cavitation nucleation agents produce tumor growth reduction and gene transfer in vivo.
Lnc-SNHG1 Activates the TGFBR2/SMAD3 and RAB11A/Wnt/?-Catenin Pathway by Sponging MiR-302/372/373/520 in Invasive Pituitary Tumors.
Lnc-SNHG16/miR-128 axis modulates malignant phenotype through WNT/?-catenin pathway in cervical cancer cells.
LncRNA BLACAT1 Promotes Proliferation, Migration and Invasion of Prostate Cancer Cells via Regulating miR-29a-3p/DVL3 Axis.
LncRNA CASC15 promotes tumour progression through SOX4/Wnt/?-catenin signalling pathway in hepatocellular carcinoma.
LncRNA DDX11-AS1 Promotes Bladder Cancer Occurrence Via Protecting LAMB3 from Downregulation by Sponging miR-2355-5p.
LncRNA FEZF1-AS1 accelerates the migration and invasion of laryngeal squamous cell carcinoma cells through miR-4497 targeting GBX2.
LncRNA FOXC2-AS1 regulated proliferation and apoptosis of vascular smooth muscle cell through targeting miR-1253/FOXF1 axis in atherosclerosis.
LncRNA FOXD3-AS1 Promotes the Malignant Progression of Nasopharyngeal Carcinoma Through Enhancing the Transcription of YBX1 by H3K27Ac Modification.
lncRNA GAS5-promoted apoptosis in triple-negative breast cancer by targeting miR-378a-5p/SUFU signaling.
LncRNA GSTM3TV2 Promotes Cell Proliferation and Invasion via miR-597/FOSL2 Axis in Hepatocellular Carcinoma.
lncRNA LIFR?AS1 inhibits gastric carcinoma cell proliferation, migration and invasion by sponging miR?4698.
LncRNA LUCAT1/miR-181a-5p axis promotes proliferation and invasion of breast cancer via targeting KLF6 and KLF15.
LncRNA MACC1-AS1 sponges multiple miRNAs and RNA-binding protein PTBP1.
LncRNA meg3 suppresses hepatocellular carcinoma in vitro and vivo studies.
LncRNA PTCSC3/miR-574-5p Governs Cell Proliferation and Migration of Papillary Thyroid Carcinoma via Wnt/?-Catenin Signaling.
LncRNA PTTG3P Sponge Absorbs microRNA-155-5P to Promote Metastasis of Colorectal Cancer.
LncRNA SNHG3 promotes clear cell renal cell carcinoma proliferation and migration by upregulating TOP2A.
LncRNA UCA1 promotes the invasion and EMT of bladder cancer cells by regulating the miR-143/HMGB1 pathway.
LncRNA XIST Contributes to Cisplatin Resistance of Lung Cancer Cells by Promoting Cellular Glycolysis through Sponging miR-101-3p.
LncRNA-CCAT1 Promotes Migration, Invasion, and EMT in Intrahepatic Cholangiocarcinoma Through Suppressing miR-152.
LncRNA-PCAT-1 promotes non-small cell lung cancer progression by regulating miR-149-5p/LRIG2 axis.
Locally invasive, castrate-resistant prostate cancer in a Pten/Trp53 double knockout mouse model of prostate cancer monitored with non-invasive bioluminescent imaging.
Long non-coding RNA FER1L4 inhibits prostate cancer progression via sponging miR-92a-3p and upregulation of FBXW7.
Long Non-Coding RNA LEF1-AS1 Promotes Migration, Invasion and Metastasis of Colon Cancer Cells Through miR-30-5p/SOX9 Axis.
Long non-coding RNA MIR155HG knockdown suppresses cell proliferation, migration and invasion in NSCLC by upregulating TP53INP1 directly targeted by miR-155-3p and miR-155-5p.
Long non-coding RNA NEAT1 facilitates pancreatic cancer progression through negative modulation of miR-506-3p.
Long non-coding RNA taurine upregulated 1 enhances tumor-induced angiogenesis through inhibiting microRNA-299 in human glioblastoma.
Long non?coding RNA ferritin heavy polypeptide 1 pseudogene 3 controls glioma cell proliferation and apoptosis via regulation of the microRNA?224?5p/tumor protein D52 axis.
Long noncoding RNA 00976 promotes pancreatic cancer progression through OTUD7B by sponging miR-137 involving EGFR/MAPK pathway.
Long noncoding RNA DARS-AS1 regulates TP53 ubiquitination and affects ovarian cancer progression by modulation miR-194-5p/RBX1 axis.
Long noncoding RNA DLEU1 aggravates glioma progression via the miR-421/MEF2D axis.
Long noncoding RNA GACAT3 promotes glioma progression by sponging miR-135a.
Long noncoding RNA KCNQ1OT1 promotes proliferation, migration, and invasion in maxillary sinus squamous cell carcinoma by regulating miR-204/EphA7 axis.
Long noncoding RNA MIR155HG facilitates pancreatic cancer progression through negative regulation of miR-802.
Long Noncoding RNA miR210HG Sponges miR-503 to Facilitate Osteosarcoma Cell Invasion and Metastasis.
Long noncoding RNA ROR promotes proliferation and invasion of colorectal cancer by inhibiting tumor suppressor gene NF2 through interacting with miR-223-3p.
Long noncoding RNA SNHG14 promotes malignancy of prostate cancer by regulating with miR-5590-3p/YY1 axis.
Long-Chain Non-Coding RNA (lncRNA) MT1JP Suppresses Biological Activities of Lung Cancer by Regulating miRNA-423-3p/Bim Axis.
Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery.
Luciferase activity as a marker of tumor burden and as an indicator of tumor response to antineoplastic therapy in vivo.
Luciferase does not Alter Metabolism in Cancer Cells.
Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo.
Luciferase fragment complementation imaging in preclinical cancer studies.
Luciferase inhibition by a novel naphthoquinone.
Luciferase Reporter Assays to Study Transcriptional Activity of Hedgehog Signaling in Normal and Cancer Cells.
Luciferase-assisted detection of extracellular ATP and ATP metabolites during immunogenic death of cancer cells.
LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis.
Lymph node resection induces the activation of tumor cells in the lungs.
Magnetic resonance-guided regional gene delivery strategy using a tumor stroma-permeable nanocarrier for pancreatic cancer.
Mammographically dense human breast tissue stimulates MCF10DCIS.com progression to invasive lesions and metastasis.
Manganese superoxide dismutase: beyond life and death.
MAPK/AP-1-Targeted Anti-Inflammatory Activities of Xanthium strumarium.
Marine two-headed sphingolipid-like compound rhizochalin inhibits EGF-induced transformation of JB6 P+ Cl41 cells.
Matrix Metalloproteinase Responsive, Proximity-activated Polymeric Nanoparticles for siRNA Delivery.
Measuring cytotoxicity by bioluminescence imaging outperforms the standard chromium-51 release assay.
Mechanism of Prolactin Inhibition of miR-135b via Methylation in Goat Mammary Epithelial Cells.
Mechanisms of Yangjing Capsule in Leydig Cell Apoptosis and Testosterone Synthesis via Promoting StAR Expression.
Mesenchymal stem cells are efficiently transduced with adenoviruses bearing type 35-derived fibers and the transduced cells with the IL-28A gene produces cytotoxicity to lung carcinoma cells co-cultured.
Metallothionein-1 as a biomarker of altered redox metabolism in hepatocellular carcinoma cells exposed to sorafenib.
Metastasizing, Luciferase Transduced MAT?Lu Rat Prostate Cancer Models: Follow up of Bolus and Metronomic Therapy with Doxorubicin as Model Drug.
Metastatic burden in nude mice organs measured using prostate tumor PC-3 cells expressing the luciferase gene as a quantifiable tumor cell marker.
Methodologies for the establishment of an orthotopic transplantation model of ovarian cancer in mice.
Methods to Generate and Assay for Distinct Stages of Cancer Metastasis in Adult Drosophila melanogaster.
MEX3C promotes osteosarcoma malignant progression through negatively regulating FGF14.
MHP-1 inhibits cancer metastasis and restores topotecan sensitivity via regulating epithelial-mesenchymal transition and TGF-? signaling in human breast cancer cells.
Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.
Microparticle Depots for Controlled and Sustained Release of Endosomolytic Nanoparticles.
MicroR-545 mediates colorectal cancer cells proliferation through up-regulating epidermal growth factor receptor expression in HOTAIR long non-coding RNA dependent.
MicroRNA-103a Curtails the Stemness of Non-Small Cell Lung Cancer Cells by Binding OTUB1 via the Hippo Signaling Pathway.
MicroRNA-10a promotes granulosa cells tumor development via PTEN-AKT/Wnt regulatory axis.
microRNA-126 Is a Tumor Suppressor of Granulosa Cell Tumor Mediated by Its Host Gene EGFL7.
MicroRNA-1290 promotes esophageal squamous cell carcinoma cell proliferation and metastasis.
MicroRNA-136-5p regulates gemcitabine resistance in pancreatic cancer via down-regulating ZNF32.
MicroRNA-138 directly targets TNFAIP8 and acts as a tumor suppressor in osteosarcoma.
MicroRNA-140-5p inhibits salivary adenoid cystic carcinoma progression and metastasis via targeting survivin.
MicroRNA-145 transcriptionally regulates Semaphorin 3A expression in prostate cancer cells.
MicroRNA-150 suppresses triple-negative breast cancer metastasis through targeting HMGA2.
MicroRNA-16 sensitizes drug-resistant breast cancer cells to Adriamycin by targeting Wip1 and Bcl-2.
MicroRNA-16 suppressed the invasion and migration of osteosarcoma by directly inhibiting RAB23.
MicroRNA-186 suppresses lung cancer progression by targeting SIRT6.
MicroRNA-18a inhibits hypoxia-inducible factor 1? activity and lung metastasis in basal breast cancers.
MicroRNA-191 promotes pancreatic cancer progression by targeting USP10.
MicroRNA-200c inhibits apoptosis in pituitary adenoma cells by targeting the PTEN/Akt signaling pathway.
MicroRNA-200c suppresses tumor metastasis in oral squamous carcinoma by inhibiting epithelial-mesenchymal transition.
MicroRNA-204 increases sensitivity of neuroblastoma cells to cisplatin and is associated with a favourable clinical outcome.
MicroRNA-205 directly targets Krüppel-like factor 12 and is involved in invasion and apoptosis in basal-like breast carcinoma.
MicroRNA-205 Inhibits Src-Mediated Oncogenic Pathways in Renal Cancer.
microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN.
MicroRNA-21-5p induces the metastatic phenotype of human cervical carcinoma cells
MicroRNA-218 Negatively Regulates Osteoclastogenic Differentiation by Repressing the Nuclear Factor-?B Signaling Pathway and Targeting Tumor Necrosis Factor Receptor 1.
MicroRNA-26b regulates cancer proliferation migration and cell cycle transition by suppressing TRAF5 in esophageal squamous cell carcinoma.
MicroRNA-301a inhibits the progression of osteosarcoma by regulating DEC2.
MicroRNA-31 functions as an oncogenic microRNA in cutaneous squamous cell carcinoma cells by targeting RhoTBT1.
MicroRNA-331 inhibits development of gastric cancer through targeting musashi1.
MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells.
MicroRNA-361-3p regulates retinoblastoma cell proliferation and stemness by targeting hedgehog signaling.
MicroRNA-365a-3p inhibits c-Rel-mediated NF-?B signaling and the progression of pancreatic cancer.
MicroRNA-489-3p plays a significant role in congenital hypothyroidism through regulating neuronal cell apoptosis via targeting translationally controlled tumor protein 1.
MicroRNA-501-3p restricts prostate cancer growth through regulating cell cycle-related and expression-elevated protein in tumor/cyclin D1 signaling.
MicroRNA-590-5p antagonizes the inhibitory effect of high glucose on osteoblast differentiation by suppressing Smad7 in MC3T3-E1 cells.
MicroRNA-639 is Down-Regulated in Hepatocellular Carcinoma Tumor Tissue and Inhibits Proliferation and Migration of Human Hepatocellular Carcinoma Cells Through the KAT7/Wnt/?-Catenin Pathway.
MicroRNA-761 inhibits the metastasis of gastric cancer by negatively regulating Ras and Rab interactor 1.
MicroRNA-93 promotes bladder cancer proliferation and invasion by targeting PEDF.
MicroRNA-98 Suppress Warburg Effect by Targeting HK2 in Colon Cancer Cells.
MicroRNA-9 inhibits proliferation and progression in retinoblastoma cells by targeting PTEN.
MicroRNA23a Overexpression in Crohn's Disease Targets Tumour Necrosis Factor Alpha Inhibitor Protein 3, Increasing Sensitivity to TNF and Modifying the Epithelial Barrier.
MicroRNA?139 suppressed tumor cell proliferation, migration and invasion by directly targeting HDGF in epithelial ovarian cancer.
MicroRNA?198 suppresses prostate tumorigenesis by targeting MIB1.
MicroRNA?4284 promotes gastric cancer tumorigenicity by targeting ten-eleven translocation 1.
MicroRNA?92a promotes non?small cell lung cancer cell growth by targeting tumor suppressor gene FBXW7.
microRNA?99a inhibits cell proliferation, colony formation ability, migration and invasion by targeting fibroblast growth factor receptor 3 in prostate cancer.
Midkine promoter-based conditionally replicative adenovirus therapy for midkine-expressing human pancreatic cancer.
Mimicry of erythropoietin by a nonpeptide molecule.
miR-103 promotes the metastasis and EMT of hepatocellular carcinoma by directly inhibiting LATS2.
MiR-103/107 induces tumorigenicity in bladder cancer cell by suppressing PTEN.
miR-1207-5p regulates the sensitivity of triple-negative breast cancer cells to Taxol treatment via the suppression of LZTS1 expression.
miR-124 inhibits proliferation, migration and invasion of malignant melanoma cells via targeting versican.
MiR-124 suppresses cell motility and adhesion by targeting talin 1 in prostate cancer cells.
miR-126 functions as a tumor suppressor in osteosarcoma by targeting Sox2.
miR-1269 promotes cell survival and proliferation by targeting tp53 and caspase-9 in lung cancer.
miR-1271 inhibits migration, invasion and epithelial-mesenchymal transition by targeting ZEB1 and TWIST1 in pancreatic cancer cells.
MiR-130a in the adipogenesis of human SGBS preadipocytes and its susceptibility to androgen regulation.
miR-133a functions as a tumor suppressor and directly targets FSCN1 in pancreatic cancer.
MiR-135b is a novel oncogenic factor in cutaneous melanoma by targeting LATS2.
miR-135b, upregulated in breast cancer, promotes cell growth and disrupts the cell cycle by regulating LATS2.
miR-138-5p induces aggressive traits by targeting Trp53 expression in murine melanoma cells, and correlates with poor prognosis of melanoma patients.
miR-139-5p suppresses cancer cell migration and invasion through targeting ZEB1 and ZEB2 in GBM.
MiR-140 modulates the inflammatory responses of Mycobacterium tuberculosis-infected macrophages by targeting TRAF6.
miR-144-3p, a tumor suppressive microRNA targeting ETS-1 in laryngeal squamous cell carcinoma.
MiR-155-5p accelerates the metastasis of cervical cancer cell via targeting TP53INP1.
MiR-16a regulates milk fat metabolism by targeting large tumor suppressor kinase 1 (LATS1) in bovine mammary epithelial cells.
miR-181d-5p-FOXP1 feedback loop modulates the progression of osteosarcoma.
miR-185 inhibits hepatocellular carcinoma growth by targeting the DNMT1/PTEN/Akt pathway.
miR-199b exerts tumor suppressive functions in hepatocellular carcinoma by directly targeting JAG1.
miR-19a and miR-19b Overexpression in Gliomas.
miR-202 functions as a tumor suppressor in non-small cell lung cancer by targeting STAT3.
MiR-204 suppresses cell proliferation and promotes apoptosis in ovarian granulosa cells via targeting TPT1 in polycystic ovary syndrome.
miR-205 down-regulation promotes proliferation of dermatofibrosarcoma protuberans tumor cells by regulating LRP-1 and ERK phosphorylation.
miR-21 modulates resistance of HR-HPV positive cervical cancer cells to radiation through targeting LATS1.
miR-214 activates TP53 but suppresses the expression of RELA, CTNNB1, and STAT3 in human cervical and colorectal cancer cells.
miR-214-5p Targets ROCK1 and Suppresses Proliferation and Invasion of Human Osteosarcoma Cells.
miR-215 promotes cell migration and invasion of gastric cancer by targeting Retinoblastoma tumor suppressor gene 1.
miR-215 promotes malignant progression of gastric cancer by targeting RUNX1.
MiR-216a-5p inhibits tumorigenesis in Pancreatic Cancer by targeting TPT1/mTORC1 and is mediated by LINC01133.
miR-217 and CAGE form feedback loop and regulates the response to anti-cancer drugs through EGFR and HER2.
MiR-22 regulated T cell differentiation and hepatocellular carcinoma growth by directly targeting Jarid2.
MiR-222 overexpression confers cell migratory advantages in hepatocellular carcinoma through enhancing AKT signaling.
MiR-223-3p promotes the proliferation, invasion and migration of colon cancer cells by negative regulating PRDM1.
miR-27b Suppresses Tongue Squamous Cell Carcinoma Epithelial-Mesenchymal Transition by Targeting ITGA5.
miR-28-5p acts as a tumor suppressor in renal cell carcinoma for multiple antitumor effects by targeting RAP1B.
miR-29a suppresses MCF-7 cell growth by downregulating tumor necrosis factor receptor 1.
MiR-29b-3p promotes particulate matter-induced inflammatory responses by regulating the C1QTNF6/AMPK pathway.
miR-326-histone deacetylase-3 feedback loop regulates the invasion and tumorigenic and angiogenic response to anti-cancer drugs.
MiR-34a-3p alters proliferation and apoptosis of meningioma cells in vitro and is directly targeting SMAD4, FRAT1 and BCL2.
miR-361-5p modulates metabolism and autophagy via the Sp1-mediated regulation of PKM2 in prostate cancer.
miR-363 suppresses the proliferation, migration and invasion of clear cell renal cell carcinoma by downregulating S1PR1.
MiR-379 relieves myocardial injury after acute myocardial infarction by regulating tumor necrosis factor-?-induced protein 8.
miR-383 inhibits hepatocellular carcinoma cell proliferation via targeting APRIL.
miR-425 inhibits melanoma metastasis through repression of PI3K-Akt pathway by targeting IGF-1.
MiR-4262 promotes proliferation and invasion of human breast cancer cells through directly targeting KLF6 and KLF15.
MiR-4282 inhibits tumor progression through down-regulation of ZBTB2 by targeting LIN28B in oral squamous cell carcinoma.
miR-449a targets HDAC-1 and induces growth arrest in prostate cancer.
MiR-450a-5p Inhibits Gastric Cancer Cell Proliferation, Migration, and Invasion and Promotes Apoptosis via Targeting CREB1 and Inhibiting AKT/GSK-3? Signaling Pathway.
miR-454-3p Is an Exosomal Biomarker and Functions as a Tumor Suppressor in Glioma.
miR-494 promotes progression of retinoblastoma via PTEN through PI3K/AKT signaling pathway.
miR-497 regulates fatty acid synthesis via LATS2 in bovine mammary epithelial cells.
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-?-catenin pathway.
miR-508-3p concordantly silences NFKB1 and RELA to inactivate canonical NF-?B signaling in gastric carcinogenesis.
miR-520b Inhibits IGF-1R to Increase Doxorubicin Sensitivity and Promote Cell Apoptosis in Breast Cancer.
miR-545 promoted enterovirus 71 replication via directly targeting phosphatase and tensin homolog and tumor necrosis factor receptor-associated factor 6.
MiR-572 prompted cell proliferation of human ovarian cancer cells by suppressing PPP2R2C expression.
miR-590-3p suppresses cancer cell migration, invasion and epithelial-mesenchymal transition in glioblastoma multiforme by targeting ZEB1 and ZEB2.
miR-605-5p promotes invasion and proliferation by targeting TNFAIP3 in non-small-cell lung cancer.
miR-650 Promotes the Metastasis and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Directly Inhibiting LATS2 Expression.
miR-761 inhibits human osteosarcoma progression by targeting CXCR1.
miR-885-5p upregulation promotes colorectal cancer cell proliferation and migration by targeting suppressor of cytokine signaling.
MiR-887 Promotes the Progression of Hepatocellular Carcinoma via Targeting VHL.
miR-92a Inhibits Peritoneal Dissemination of Ovarian Cancer Cells by Inhibiting Integrin ?5 Expression.
MiR-93 Promotes Tumorigenesis and Metastasis of Non-Small Cell Lung Cancer Cells by Activating the PI3K/Akt Pathway via Inhibition of LKB1/PTEN/CDKN1A.
MiR-93-5p up-regulation is involved in non-small cell lung cancer cells proliferation and migration and poor prognosis.
miR-938 promotes colorectal cancer cell proliferation via targeting tumor suppressor PHLPP2.
miRNA-30a functions as a tumor suppressor by downregulating cyclin E2 expression in castration-resistant prostate cancer.
miRNA-99b-5p suppresses liver metastasis of colorectal cancer by down-regulating mTOR.
miRNA?328 overexpression confers cisplatin resistance in non?small cell lung cancer via targeting of PTEN.
Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer.
Mitochondrial DNA mutation stimulates prostate cancer growth in bone stromal environment.
MNS16A tandem repeat minisatellite of human telomerase gene: functional studies in colorectal, lung and prostate cancer.
Modeling astrocytoma pathogenesis in vitro and in vivo using cortical astrocytes or neural stem cells from conditional, genetically engineered mice.
Modifications to the INSM1 promoter to preserve specificity and activity for use in adenoviral gene therapy of neuroendocrine carcinomas.
Modulation of T-cell activation through protein kinase C- or A-dependent signalling pathways synergistically increases human immunodeficiency virus long terminal repeat induction by cytomegalovirus immediate-early proteins.
Molecular and metabolic pathways mediating curative treatment of a non-Hodgkin B cell lymphoma by Sindbis viral vectors and anti-4-1BB monoclonal antibody.
Molecular Cloning of the Human Platelet-Derived Growth Factor Receptor beta (PDGFR-beta) Promoter and Drug Targeting of the G-Quadruplex-Forming Region To Repress PDGFR-beta Expression.
Molecular cloning, genomic organization, and identification of the promoter for the human pituitary tumor transforming gene (PTTG).
Molecular structure of the human gonadotropin-releasing hormone receptor gene.
Monitoring Atsttrin-Mediated Inhibition of TNF?/NF-?? Activation Through In Vivo Bioluminescence Imaging.
Monitoring luciferase-labeled human prostate stem cell antigen-expressing tumor growth in a mouse model.
Monitoring the dynamics of clonal tumour evolution in vivo using secreted luciferases.
Monitoring the efficacy of adoptively transferred prostate cancer-targeted human T lymphocytes with PET and bioluminescence imaging.
Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model.
Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence.
Multifunctional Polymeric Carrier for Co-Delivery of MRI Contrast Agents and siRNA to Tumors.
Multimodal fluorescence- and bioluminescence imaging reveals transfection potential of intratracheally administered polyplexes for breast cancer lung metastases.
Multimodal imaging guided preclinical trials of vascular targeting in prostate cancer.
Multimodal imaging of a humanized orthotopic model of hepatocellular carcinoma in immunodeficient mice.
Multivalent dendrimer vectors with DNA intercalation motifs for gene delivery.
Murine neuronal progenitor cells are preferentially recruited to tumor vasculature via alpha4-integrin and SDF-1alpha-dependent mechanisms.
Murine orthotopic model for the assessment of chemoradiotherapeutic interventions in rectal cancer.
Murine tyrosinase expressed by a T7 vector in bone marrow-derived dendritic progenitors effectively prevents and eradicates melanoma tumors in mice.
Mutant Bik gene transferred by cationic liposome inhibits peritoneal disseminated murine colon cancer.
Mycobacterium bovis BCG promotes tumor cell survival from tumor necrosis factor-?-induced apoptosis.
Natural Antioxidant Resveratrol Suppresses Uterine Fibroid Cell Growth and Extracellular Matrix Formation In Vitro and In Vivo.
NDRG2 ablation reprograms metastatic cancer cells towards glutamine dependence via the induction of ASCT2.
Near infrared photoimmunotherapy in the treatment of disseminated peritoneal ovarian cancer.
Near infrared photoimmunotherapy prevents lung cancer metastases in a murine model.
Neutralizing anti-vascular endothelial growth factor antibody inhibits further growth of established prostate cancer and metastases in a pre-clinical model.
New in vivo avatars of diffuse intrinsic pontine gliomas (DIPG) from stereotactic biopsies performed at diagnosis.
NF-?B inhibitory activities of glycosides and alkaloids from Zanthoxylum schinifolium stems.
NF-?B-mediated miR-650 plays oncogenic roles and activates AKT/ERK/NF-?B pathways by targeting RERG in glioma cells.
NF-kappaB activation by N-CAM and cytokines in astrocytes is regulated by multiple protein kinases and redox modulation.
NF-kappaB and not the MAPK signaling pathway regulates GADD45beta expression during acute inflammation.
Niclosamide Induces Cell Cycle Arrest in G1 Phase in Head and Neck Squamous Cell Carcinoma Through Let-7d/CDC34 Axis.
Nm23-H1 was involved in regulation of KAI1 expression in high-metastatic lung cancer cells L9981.
Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse model.
Non-invasive detection of bladder cancer via expression-targeted gene delivery.
Non-invasive imaging of firefly luciferase reporter gene expression using bioluminescence imaging in human prostate cancer models.
Non-invasive monitoring of hypoxia-inducible factor activation by optical imaging during antiangiogenic treatment in a xenograft model of ovarian carcinoma.
Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: correlation with magnetic resonance imaging determined tumor volume and longitudinal use in assessing tumor growth and antiangiogenic treatment effect.
Noninvasive delivery of oligonucleotide by penetratin-modified polyplexes to inhibit protein expression of intraocular tumor.
Noninvasive imaging and quantification of epidermal growth factor receptor kinase activation in vivo.
Noninvasive imaging for monitoring of viable cancer cells using a dual-imaging reporter gene.
Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice.
Noninvasive imaging of transcriptionally restricted transgene expression following intratumoral injection of an adenovirus in which the COX-2 promoter drives a reporter gene.
Noninvasive in vivo whole body luminescent analysis of luciferase labelled orthotopic prostate tumours.
Noninvasive of adenovirus tumor retargeting in living subjects by a soluble adenovirus receptor-epidermal growth factor (sCAR-EGF) fusion protein.
Nonstructural 5A protein of hepatitis C virus modulates tumor necrosis factor alpha-stimulated nuclear factor kappa B activation.
Novel Dual-Action Targeted Nanomedicine in Mice With Metastatic Thyroid Cancer and Pancreatic Neuroendocrine Tumors.
Novel Functional Germline Variants in the VEGF Receptor 2 Gene and Their Effect on Gene Expression and Microvessel Density in Lung Cancer.
Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals.
Novel oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer xenografts and exhibits abscopal effect at a single low dose.
Novel prostate-specific promoter derived from PSA and PSMA enhancers.
Novel shielded transferrin-polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer.
Novel, genetically induced mouse model that recapitulates the histological morphology and immunosuppressive tumor microenvironment of metastatic peritoneal carcinomatosis.
Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001.
Nuclear factor kappa B and tumor necrosis factor-alpha modulation of transcription of the mouse testis- and pre-implantation development-specific Rnf33/Trim60 gene.
Nuclear factor kappa B-dependent gene transcription in cholecystokinin- and tumor necrosis factor-alpha-stimulated isolated acinar cells is regulated by p38 mitogen-activated protein kinase.
Nuclear factor-kappaB activation by the photochemotherapeutic agent verteporfin.
Nucling interacts with nuclear factor-kappaB, regulating its cellular distribution.
NUMB suppression by miR-9-5P enhances CD44+ prostate cancer stem cell growth and metastasis.
Oestrogen receptor positive breast cancer metastasis to bone: inhibition by targeting the bone microenvironment in vivo.
Oligonucleotides conjugated with short chemically defined polyethylene glycol chains are efficient antisense agents.
Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer.
Oncolytic vaccinia virotherapy of anaplastic thyroid cancer in vivo.
OncomiR-196 promotes an invasive phenotype in oral cancer through the NME4-JNK-TIMP1-MMP signaling pathway.
Oncostatin M promotes mesenchymal stem cell-stimulated tumor growth through a paracrine mechanism involving periostin and TGFBI.
Optical imaging of tumor cells in hollow fibers: evaluation of the antitumor activities of anticancer drugs and target validation.
Optical imaging of tumor hypoxia and evaluation of efficacy of a hypoxia-targeting drug in living animals.
Optical imaging: bacteria, viruses, and mammalian cells encoding light-emitting proteins reveal the locations of primary tumors and metastases in animals.
Optimising ultrasound-mediated gene transfer (sonoporation) in vitro and prolonged expression of a transgene in vivo: potential applications for gene therapy of cancer.
Optimization and Internalization Mechanisms of PEGylated Adenovirus Vector with Targeting Peptide for Cancer Gene Therapy.
Optimizing live-animal bioluminescence imaging prediction of tumor burden in human prostate cancer xenograft models in SCID-NSG mice.
Organ-selective chemoresistance in metastasis from human breast cancer cells: inhibition of apoptosis, genetic variability and microenvironment at the metastatic focus.
Orthotopic Esophageal Cancers: Intraesophageal Hyperthermia-enhanced Direct Chemotherapy in Rats.
Orthotopic model of canine osteosarcoma in athymic rats for evaluation of stereotactic radiotherapy.
Over-expression of human PP5 gene in mice induces corneal hyperplasia and leads to ocular surface squamous neoplasia.
Overexpression of Bcl-xL in human breast cancer cells enhances organ-selective lymph node metastasis.
Overexpression of Kpn?1 and Kpn?2 importin proteins in cancer derives from deregulated E2F activity.
Overexpression of LIMD2 promotes the progression of non-small cell lung cancer.
Overexpression of microRNA-495 suppresses the proliferation and invasion and induces the apoptosis of osteosarcoma cells by targeting high-mobility group nucleosome-binding domain 5.
Overexpression of microRNA?101 causes anti?tumor effects by targeting CREB1 in colon cancer.
Overexpression of miR-191 Predicts Poor Prognosis and Promotes Proliferation and Invasion in Esophageal Squamous Cell Carcinoma.
Overexpression of TP53 mutation-associated microRNA-182 promotes tumor cell proliferation and migration in head and neck squamous cell carcinoma.
P329G-CAR-J: a novel Jurkat-NFAT-based CAR-T reporter system recognizing the P329G Fc mutation.
p53 Loses grip on PIK3CA expression leading to enhanced cell survival during platinum resistance.
Paradoxical triiodothyronine suppression of S14 transcription in permanent hepatic cell lines.
Pegylated immuno-lipopolyplexes: A novel non-viral gene delivery system for liver cancer therapy.
Peptide-Targeted Polyplexes for Aerosol-Mediated Gene Delivery to CD49f-Overexpressing Tumor Lesions in Lung.
Peptidyl Arginine Deiminase, Type II (PADI2) Is Involved in Urothelial Bladder Cancer.
Peritoneal Metastatic Cancer Stem Cells of Gastric Cancer with Partial Mesenchymal-Epithelial Transition and Enhanced Invasiveness in an Intraperitoneal Transplantation Model.
Persistent Infection of Simian Foamy Virus Derived from the Japanese Macaque Leads to the High-Level Expression of microRNA that Resembles the miR-1 microRNA Precursor Family.
PET imaging and optical imaging with D-luciferin [11C]methyl ester and D-luciferin [11C]methyl ether of luciferase gene expression in tumor xenografts of living mice.
Pharmacokinetic modeling of tumor bioluminescence implicates efflux, and not influx, as the bigger hurdle in cancer drug therapy.
Pharmacological inhibition of 17?-hydroxysteroid dehydrogenase impairs human endometrial cancer growth in an orthotopic xenograft mouse model.
Pharmacological Regulation of Tumor Hypoxia in Model Murine Tumors and Spontaneous Canine Tumors.
pHLuc, a Ratiometric Luminescent Reporter for in vivo Monitoring of Tumor Acidosis.
Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells.
Photo activation of HPPH encapsulated in "Pocket" liposomes triggers multiple drug release and tumor cell killing in mouse breast cancer xenografts.
Phototoxicity of flavoprotein miniSOG induced by bioluminescence resonance energy transfer in genetically encoded system NanoLuc-miniSOG is comparable with its LED-excited phototoxicity.
Phthalocyanine-based mesoporous organosilica nanoparticles: NIR photodynamic efficiency and siRNA photochemical internalization.
Physical activity modulates mononuclear phagocytes in mammary tissue and inhibits tumor growth in mice.
Pimobendan inhibits the activation of transcription factor NF-kappaB: a mechanism which explains its inhibition of cytokine production and inducible nitric oxide synthase.
Pinocembrin inhibits matrix metalloproteinase expression in chondrocytes.
Pivotal role of oxidative stress in tumor metastasis under diabetic conditions in mice.
Plasmid CpG depletion improves degree and duration of tumor gene expression after intravenous administration of polyplexes.
Plasmid DNA-Based Bioluminescence-Activated System for Photodynamic Therapy in Cancer Treatment.
Platelet-derived growth factor-specific regulation of the JE promoter in rat aortic smooth muscle cells.
Plectin-1 Targeted AAV Vector for the Molecular Imaging of Pancreatic Cancer.
PO-16 - ASK1 regulates tumor lung metastasis and platelet functions.
Polo-like kinase 1 regulates cell proliferation and is targeted by miR-593* in esophageal cancer.
Polyethyleneimine/DNA polyplexes with reduction-sensitive hyaluronic acid derivatives shielding for targeted gene delivery.
Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application.
Polymeric Micellar Delivery of Novel Microtubule Destabilizer and Hedgehog Signaling Inhibitor for Treating Chemoresistant Prostate Cancer.
Polymorphisms in the promoter region of the neutrophil elastase gene are associated with lung cancer development.
Polyplex-microbubble hybrids for ultrasound-guided plasmid DNA delivery to solid tumors.
Polythiophenes with Cationic Phosphonium Groups as Vectors for Imaging, siRNA Delivery, and Photodynamic Therapy.
Porcine transmissible gastroenteritis virus nonstructural protein 2 contributes to inflammation via NF-?B activation.
Position-independent expression of a human nerve growth factor-luciferase reporter gene cloned on a yeast artificial chromosome vector.
Post-transcriptional regulation of the DUSP6/MKP-3 phosphatase by MEK/ERK signaling and hypoxia.
Posttranscriptional regulation of protein expression in human epithelial carcinoma cells by adenine-uridine-rich elements in the 3'-untranslated region of tumor necrosis factor-alpha messenger RNA.
Potent antitumoral efficacy of a novel replicative adenovirus CNHK300 targeting telomerase-positive cancer cells.
Potent calcium phosphate nanoparticle surface coating for in vitro and in vivo siRNA delivery: a step toward multifunctional nanovectors.
Potent Nrf2-inducing, antioxidant, and anti-inflammatory effects and identification of constituents validate the anti-cancer use of Uvaria chamae and Olax subscorpioidea.
Potential action of IGF-1 and EGF on androgen receptor nuclear transfer and transactivation in normal and cancer human prostate cell lines.
Potential Onco-Suppressive Role of miR122 and miR144 in Uveal Melanoma through ADAM10 and C-Met Inhibition.
Potential tumor-targeting peptide vector of histidylated oligolysine conjugated to a tumor-homing RGD motif.
Precise engineering of siRNA delivery vehicles to tumors using polyion complexes and gold nanoparticles.
Preclinical evaluation of cancer immune therapy using patient-derived tumor antigen-specific T cells in a novel xenograft platform.
Preclinical evaluation of microRNA-34b/c delivery for malignant pleural mesothelioma.
Preclinical evaluation of transcriptional targeting strategy for human hepatocellular carcinoma in an orthotopic xenograft mouse model.
Preferentially enhanced gene expression from a synthetic human telomerase reverse transcriptase promoter in human cancer cells.
Preparation of Polyion Complex Micelles Using Block Copolymers for SiRNA Delivery.
Prevention of pulmonary metastasis from subcutaneous tumors by binary system-based sustained delivery of catalase.
Profiling of miRNAs in porcine Sertoli cells.
Progesterone receptor isoform A inhibits isoform B-mediated transactivation in human amnion.
Progestin-dependent stimulation of the human leukemia inhibitory factor promoter in SKUT-1B uterine tumor cells.
Proinflammatory cytokines induce amelotin transcription in human gingival fibroblasts.
Promoter-context as a determinant of glucocorticoid receptor-responsiveness to activation of p38 and JNK mitogen-activated protein (MAP) kinases.
Prompt assessment of WST11-VTP outcome using luciferase transfected tumors enables second treatment and increase in overall therapeutic rate.
Protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1) is a nuclear receptor coregulator expressed in human testis.
Protein kinase Calpha-responsive polymeric carrier: its application for gene delivery into human cancers.
Proteomic screening of anaerobically regulated promoters from Salmonella and its antitumor applications.
PTEN knockout prostate cancer as a model for experimental immunotherapy.
PTPRA facilitates cancer growth and migration via the TNF-?-mediated PTPRA-NF-?B pathway in MCF-7 breast cancer cells.
Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis.
Pyridylthiourea-grafted polyethylenimine offers an effective assistance to siRNA-mediated gene silencing in vitro and in vivo.
Quantitative and Functional Requirements for Bioluminescent Cancer Models.
Quantitative and in vivo activity of adenoviral-producing cells made by cotransduction of a replication-defective adenovirus and a replication-enabling plasmid.
RAB31 is targeted by miR-26b and serves a role in the promotion of osteosarcoma.
Radiation-mediated up-regulation of gene expression from replication-defective adenoviral vectors: implications for sodium iodide symporter gene therapy.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Radiotherapy combined with an engineered of Salmonella typhimurium inhibits tumor growth in a mouse model of colon cancer.
RanGTPase: A Candidate for Myc-Mediated Cancer Progression.
Ranpirnase Interferes with NF-?B Pathway and MMP9 Activity, Inhibiting Malignant Mesothelioma Cell Invasiveness and Xenograft Growth.
Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging.
Rapid formulation of redox-responsive oligo-?-aminoester polyplexes with siRNA via jet printing.
Rapid identification, isolation, and evaluation on anti-neuroinflammatory activity of limonoids derivatives from the root bark of Dictamnus dasycarpus.
Rapid obtention of stable, bioluminescent tumor cell lines using a tCD2-luciferase chimeric construct.
Real-time imaging of tumors using replication-competent light-emitting microorganisms.
Real-time monitoring of tumor progression and drug responses in a preclinical mouse model of prostate cancer.
Recognition and killing of cancer stem-like cell population in hepatocellular carcinoma cells by cytokine-induced killer cells via NKG2d-ligands recognition.
Recombinant adeno-associated virus for the generation of autologous, gene-modified tumor vaccines: evidence for a high transduction efficiency into primary epithelial cancer cells.
Registered report: the microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44.
Regression of glioma tumor growth in F98 and U87 rat glioma models by the Nitrone OKN-007.
Regulation of function of the murine luteinizing hormone receptor promoter by cis- and trans-acting elements in mouse Leydig tumor cells.
Regulation of IL-8 promoter activity by verrucarin A in human monocytic THP-1 cells.
Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1).
Regulation of NF-?B activity in astrocytes: effects of flavonoids at dietary-relevant concentrations.
Regulation of porcine classical and nonclassical MHC class I expression.
Regulation of the rat proopiomelanocortin gene expression in AtT-20 cells. II: Effects of the pituitary adenylate cyclase-activating polypeptide and vasoactive intestinal polypeptide.
Regulatory sequence analysis of semaphorin 4D 5' non-coding region.
Repetitive, noninvasive imaging of cyclooxygenase-2 gene expression in living mice.
Replacement of quaternary ammonium headgroups by tri-ornithine in cationic lipids for the improvement of gene delivery in vitro and in vivo.
Replication-deficient vaccinia virus gene therpay vector: evaluation of exogenous gene expression mediated by PUV-inactivated virus in glioma cells.
Reporter gene expression in fish following cutaneous infection with pantropic retroviral vectors.
Reporter protein complementation imaging assay to screen and study Nrf2 activators in cells and living animals.
Repression of MicroRNA-372 by Arsenic Sulphide Inhibits Prostate Cancer Cell Proliferation and Migration through Regulation of large tumour suppressor kinase 2.
Repression of the rat steroidogenic acute regulatory (StAR) protein gene by PGF2alpha is modulated by the negative transcription factor DAX-1.
Response to fish specific reproductive hormones and endocrine disrupting chemicals of a Sertoli cell line expressing endogenous receptors from an endemic cyprinid Gnathopogon caerulescens.
Restoration of miR-101 suppresses lung tumorigenesis through inhibition of DNMT3a-dependent DNA methylation.
Restoration of RNA helicase DDX5 suppresses hepatitis B virus (HBV) biosynthesis and Wnt signaling in HBV-related hepatocellular carcinoma.
Resveratrol inhibits LPS-induced epithelial-mesenchymal transition in mouse melanoma model.
Retargeting of Human T Cells to Tumor-Associated MUC1: The Evolution of a Chimeric Antigen Receptor.
Retinoic acids up-regulate steroidogenic acute regulatory protein gene.
Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy.
Reversal of cisplatin resistance in human gastric cancer cells by a wogonin-conjugated Pt(IV) prodrug via attenuating Casein Kinase 2-mediated Nuclear Factor-?B pathways.
Rhenium-186 liposomes as convection-enhanced nanoparticle brachytherapy for treatment of glioblastoma.
RIP140 Represses Intestinal Paneth Cell Differentiation and Interplays with SOX9 Signaling in Colorectal Cancer.
RNA splicing factor USP39 promotes glioma progression by inducing TAZ mRNA maturation.
Role of the mitogen-activated protein kinases in cytokine-mediated inhibition of insulin gene expression.
RP11-284F21.9 promotes oral squamous cell carcinoma development via the miR-383-5p/MAL2 axis.
Rs531564 polymorphism in microRNA-214 regulates interleukin-6R expression in anal fissure patients to affect the risk of anal abscess formation.
rs78378222 polymorphism in the 3'-untranslated region of TP53 contributes to development of age-associated cataracts by modifying microRNA-125b-induced apoptosis of lens epithelial cells.
RXR? and LXR activate two promoters in placenta- and tumor-specific expression of PLAC1.
S100A4 suppresses cancer stem cell proliferation via interaction with the IKK/NF-?B signaling pathway.
Safe and effective delivery of small interfering RNA with polymer- and liposomes-based complexes.
Saporin as a novel suicide gene in anticancer gene therapy.
Saporin suicide gene therapy.
Scatter factor protects tumor cells against apoptosis caused by TRAIL.
Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells.
Screening Method for Anti-Colon Cancer Drugs Using Two Sensor Cell Lines with Human ?4-Galactosyltransferase 4 Gene Promoters.
Selective blockade of DCAMKL-1 results in tumor growth arrest by a Let-7a MicroRNA-dependent mechanism.
Selective transfection with osmotically active sorbitol modified PEI nanoparticles for enhanced anti-cancer gene therapy.
Selenium nanoparticles (SeNPs) have potent antitumor activity against prostate cancer cells through the upregulation of miR-16.
Self-assembled carboxymethyl poly (L-histidine) coated poly (?-amino ester)/DNA complexes for gene transfection.
Semliki Forest Virus Expressing IL-12 Induces Antiviral and Antitumoral Responses in Woodchucks With Chronic Viral Hepatitis and HCC.
Sensitive High-Throughput Assays for Tumour Burden Reveal the Response of a Drosophila melanogaster Model of Colorectal Cancer to Standard Chemotherapies.
Sensitive in vitro test systems to determine androgenic/antiandrogenic activity.
Sensitization of Gastric Cancer Cells to 5-FU by MicroRNA-204 Through Targeting the TGFBR2-Mediated Epithelial to Mesenchymal Transition.
Sequence and time dependence of transfection efficiency of electrically-assisted gene delivery to tumors in mice.
Sequential intravenous injection of anionic polymer and cationic lipoplex of siRNA could effectively deliver siRNA to the liver.
Serum-based tracking of de novo initiated liver cancer progression reveals early immunoregulation and response to therapy.
Severe pulmonary metastasis in obese and diabetic mice.
Significance of HIF-1-active cells in angiogenesis and radioresistance.
Silencing of antiapoptotic survivin gene by multiple approaches of RNA interference technology.
Silica cloaking of adenovirus enhances gene delivery while reducing immunogenicity.
Silk-elastinlike protein polymers improve the efficacy of adenovirus thymidine kinase enzyme prodrug therapy of head and neck tumors.
Single nucleotide polymorphisms in the MYLKP1 pseudogene are associated with increased colon cancer risk in African Americans.
Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility.
siRNA delivery to lung-metastasized tumor by systemic injection with cationic liposomes.
siRNA Lipid Nanoparticle Potently Silences Clusterin and Delays Progression When Combined with Androgen Receptor Cotargeting in Enzalutamide-Resistant Prostate Cancer.
Sleeping Beauty-mediated suicide gene therapy of hepatocellular carcinoma.
Slow disease progression in a C57BL/6 pten-deficient mouse model of prostate cancer.
Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ?Np73 Inhibition and p73 Activation.
sMicroRNA-1290 inhibits cells proliferation and migration by targeting FOXA1 in gastric cancer cells.
SOX17 antagonizes WNT/?-catenin signaling pathway in hepatocellular carcinoma.
SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells.
Sp1 regulates Raf/MEK/ERK-induced p21(CIP1) transcription in TP53-mutated cancer cells.
Spatiotemporal microRNA profile in peripheral nerve regeneration: miR-138 targets vimentin and inhibits Schwann cell migration and proliferation.
Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice.
Src is the primary target of aripiprazole, an atypical antipsychotic drug, in its anti-tumor action.
ST14 (suppression of tumorigenicity 14) gene is a target for miR-27b, and the inhibitory effect of ST14 on cell growth is independent of miR-27b regulation.
Stabilized plasmid-lipid particles for regional gene therapy: formulation and transfection properties.
Stable luciferase expression does not alter immunologic or in vivo growth properties of GL261 murine glioma cells.
Starburst Poly(amidoamine) Dendrimer Grafted Gold Nanoparticles as a Scaffold for Folic Acid-Targeted Plasmid DNA Delivery In Vitro.
Steroidal affinity labels of the estrogen receptor. 3. Estradiol 11 beta-n-alkyl derivatives bearing a terminal electrophilic group: antiestrogenic and cytotoxic properties.
Sterol-independent regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in tumor cells.
Stresgenin B, an inhibitor of heat-induced heat shock protein gene expression, produced by Streptomyces sp. AS-9.
Structure and transcriptional function of the 5'-flanking region of rat thromboxane receptor gene.
Structure of the human steroidogenic acute regulatory protein (StAR) gene: StAR stimulates mitochondrial cholesterol 27-hydroxylase activity.
Sucrose ester based cationic liposomes as effective non-viral gene vectors for gene delivery.
Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-?B-dependent pathway downregulating MGMT expression.
Sunitinib (SU11248) inhibits growth of human ovarian cancer in xenografted mice.
Sunitinib inhibits lymphatic endothelial cell functions and lymph node metastasis in a breast cancer model through inhibition of vascular endothelial growth factor receptor 3.
Suppression of Oral Carcinoma Oncogenic Activity by microRNA-203
Suppression of pancreatic ductal adenocarcinoma growth by intratumoral delivery of attenuated Salmonella typhimurium using a dual fluorescent live tracking system.
Suppression of pancreatic tumor progression by systemic delivery of a pancreatic-cancer-specific promoter driven Bik mutant.
Suppression of phospho-p85?-GTP-Rac1 lipid raft interaction by bichalcone analog attenuates cancer cell invasion.
Surface-Modified HK:siRNA Nanoplexes with Enhanced Pharmacokinetics and Tumor Growth Inhibition.
Synergistic in vivo antitumor effect of the histone deacetylase inhibitor MS-275 in combination with interleukin 2 in a murine model of renal cell carcinoma.
Syngeneic tobacco carcinogen-induced mouse lung adenocarcinoma model exhibits PD-L1 expression and high tumor mutational burden.
Synthesis and biological evaluation of an albumin-binding prodrug of doxorubicin that is cleaved by prostate-specific antigen (PSA) in a PSA-positive orthotopic prostate carcinoma model (LNCaP).
Synthesis and biological evaluation of imidazo[1,2-a]pyrimidines and imidazo[1,2-a]pyridines as new inhibitors of the Wnt/?-catenin signaling.
Synthesis and SAR study of novel 3,3-diphenyl-1,3-dihydroindol-2-one derivatives as potent eIF2·GTP·Met-tRNAi(Met) ternary complex inhibitors.
Synthesizing oncogenic signal-processing systems that function as both "signal counters" and "signal blockers" in cancer cells.
Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy.
Systemic delivery of sticky siRNAs targeting the cell cycle for lung tumor metastasis inhibition.
Systemic Immunotherapy of Non-Muscle Invasive Mouse Bladder Cancer with Avelumab, an Anti-PD-L1 Immune Checkpoint Inhibitor.
T cell cytotoxicity toward hematologic malignancy via B7-H3 targeting.
T7 peptide-functionalized nanoparticles utilizing RNA interference for glioma dual targeting.
Targeted Brain Tumor Therapy by Inhibiting the MDM2 Oncogene: In Vitro and In Vivo Antitumor Activity and Mechanism of Action.
Targeted gene therapy and in vivo bioluminescent imaging for monitoring postsurgical recurrence and metastasis in mouse models of liver cancer.
Targeted gene transfer into head and neck squamous cell carcinoma by nanosecond pulsed laser-induced stress waves.
Targeted gene transfer to hepatocellular carcinoma cells in vitro using a novel monoclonal antibody-based gene delivery system.
Targeted minicircle DNA delivery using folate-poly(ethylene glycol)-polyethylenimine as non-viral carrier.
Targeted Phototherapy for Malignant Pleural Mesothelioma: Near-Infrared Photoimmunotherapy Targeting Podoplanin.
Targeted suicide gene transfections reveal promising results in nu/nu mice with aggressive neuroblastoma.
Targeted therapy of spontaneous murine pancreatic tumors by polymeric micelles prolongs survival and prevents peritoneal metastasis.
Targeted therapy with fatty acid synthase inhibitors in a human prostate carcinoma LNCaP/tk-luc-bearing animal model.
Targeting gene expression to tumor cells with loss of wild-type p53 function.
Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition.
Targeting of prostate cancer cells by a cytotoxic lentiviral vector containing a prostate stem cell antigen (PSCA) promoter.
Targeting of syndecan-1 by microRNA miR-10b promotes breast cancer cell motility and invasiveness via a Rho-GTPase- and E-cadherin-dependent mechanism.
Targeting Survivin Enhances Chemosensitivity in Retinoblastoma Cells and Orthotopic Tumors.
TET1 suppresses colon cancer proliferation by impairing ?-catenin signal pathway.
Tetraspanin CD9 is Regulated by miR-518f-5p and Functions in Breast Cell Migration and In Vivo Tumor Growth.
TGF?-Stimulated MicroRNA-21 Utilizes PTEN to Orchestrate AKT/mTORC1 Signaling for Mesangial Cell Hypertrophy and Matrix Expansion.
The 5'-flanking region of the rat luteinizing hormone/chorionic gonadotropin receptor gene confers Leydig cell expression and negative regulation of gene transcription by 3',5'-cyclic adenosine monophosphate.
The Ancient Chinese Decoction Yu-Ping-Feng Suppresses Orthotopic Lewis Lung Cancer Tumor Growth Through Increasing M1 Macrophage Polarization and CD4+ T Cell Cytotoxicity.
The anti-infection drug furazolidone inhibits NF-?B signaling and induces cell apoptosis in small cell lung cancer.
The anticancer activity of 3- and 10-bromofascaplysins is mediated by caspase-8, -9, -3-dependent apoptosis.
The application of a murine bone bioreactor as a model of tumor: bone interaction.
The ARF Tumor Suppressor Inhibits Tumor Cell Colonization Independent of p53 in a Novel Mouse Model of Pancreatic Ductal Adenocarcinoma Metastasis.
The Association Between -1304T>G Polymorphism in the Promoter of Mitogen-Activated Protein Kinase Kinase 4 Gene and the Risk of Cervical Cancer in Chinese Population.
The Biological Function of TUSC7/miR-1224-3p Axis in Triple-Negative Breast Cancer.
The brain microenvironment negatively regulates miRNA-768-3p to promote K-ras expression and lung cancer metastasis.
The BRCA1 3'-UTR: 5711+421T/T_5711+1286T/T Genotype Is a Possible Breast and Ovarian Cancer Risk Factor.
The carcinoma-specific epithelial glycoprotein-2 promoter controls efficient and selective gene expression in an adenoviral context.
The CDX1-microRNA-215 axis regulates colorectal cancer stem cell differentiation.
The chemopreventive compound curcumin is an efficient inhibitor of Epstein-Barr virus BZLF1 transcription in Raji DR-LUC cells.
The cloning and activity of human Hes1 gene promoter.
The coordination between ZNF217 and LSD1 contributes to hepatocellular carcinoma progress and is negatively regulated by miR-101.
The cyclo-oxygenase 2 promoter is induced in nontarget cells following adenovirus infection, but an AU-rich 3'-untranslated region destabilization element can increase specificity.
The differential capacity of glucocorticoids and progestins to alter chromatin structure and induce gene expression in human breast cancer cells.
The effect of DNA-alkylating agents on gene expression from two integrated reporter genes in a mouse mammary tumor line.
The effect of high intensity focused ultrasound on luciferase activity on two tumor cell lines in vitro, under the control of a CMV promoter.
The efficacy of nuclease-resistant Chol-siRNA in primary breast tumors following complexation with PLL-PEG(5K).
The expression level of luciferase within tumour cells can alter tumour growth upon in vivo bioluminescence imaging.
The FKH domain in FOXP3 mRNA frequently contains mutations in hepatocellular carcinoma that influence the subcellular localization and functions of FOXP3.
The gene transfection efficiency of a folate-PEI600-cyclodextrin nanopolymer.
The glycosyltransferase ST6Gal-I is enriched in cancer stem-like cells in colorectal carcinoma and contributes to their chemo-resistance.
The Herbal Drug Melampyrum pratense L. (Koch): Isolation and Identification of Its Bioactive Compounds Targeting Mediators of Inflammation.
The human splice variant ?16HER2 induces rapid tumor onset in a reporter transgenic mouse.
The hypoxia-inducible factor-1? activates ectopic production of fibroblast growth factor 23 in tumor-induced osteomalacia.
The inducible isoform of CREM (inducible cAMP early repressor, ICER) is a repressor of CYP19 rat ovarian promoter.
The inflammatory circuitry of miR-149 as a pathological mechanism in osteoarthritis.
The JNK inhibitor AS602801 Synergizes with Enzalutamide to Kill Prostate Cancer Cells In Vitro and In Vivo and Inhibit Androgen Receptor Expression.
The lncRNA ZEB2-AS1 is upregulated in gastric cancer and affects cell proliferation and invasion via miR-143-5p/HIF-1? axis.
The long non-coding RNA H19-derived miR-675 modulates human gastric cancer cell proliferation by targeting tumor suppressor RUNX1.
The long non-coding RNA SUMO1P3 facilitates breast cancer progression by negatively regulating miR-320a.
The membrane protein of SARS-CoV suppresses NF-kappaB activation.
The MYCN oncoprotein as a drug development target.
The natural product hymenialdisine inhibits interleukin-8 production in U937 cells by inhibition of nuclear factor-kappaB.
The neuropilin-1 receptor mediates enhanced tumor delivery of H2K polyplexes.
The Next Generation of Orthotopic Thyroid Cancer Models: Immunocompetent Orthotopic Mouse Models of BRAF(V600E)-Positive Papillary and Anaplastic Thyroid Carcinoma.
The Nuclear Export Inhibitor Selinexor Inhibits Hypoxia Signaling Pathways And 3D Spheroid Growth Of Cancer Cells.
The oncogenetic role of microRNA-31 as a potential biomarker in oesophageal squamous cell carcinoma.
The oncogenic RNA-binding protein Musashi1 is regulated by tumor suppressor miRNAs.
The overexpression of miR-30a affects cell proliferation of chondrosarcoma via targeting Runx2.
The power of precise bioinformatics prediction of miRNA:mRNA interactions:miR-4699 as a potential inducer of Wnt signaling pathway.
The proto-oncogene Myc drives expression of the NK cell-activating NKp30 ligand B7-H6 in tumor cells.
The putative tumor suppressor Cdx2 is overexpressed by human colorectal adenocarcinomas.
The regulation of the human tumor necrosis factor alpha promoter region in macrophage, T cell, and B cell lines.
The role and regulation of the Niemann-Pick C1 gene in adrenal steroidogenesis.
The SP1-Induced Long Noncoding RNA, LINC00339, Promotes Tumorigenesis in Colorectal Cancer via the miR-378a-3p/MED19 Axis.
The Sp1/FOXC1/HOTTIP/LATS2/YAP/?-catenin cascade promotes malignant and metastatic progression of osteosarcoma.
The stress-activated protein kinase pathway and the expression of stanniocalcin-1 are regulated by miR-146b-5p in papillary thyroid carcinogenesis.
The systemic delivery of siRNAs by a cell penetrating peptide, low molecular weight protamine.
The Third Generation Anti-HER2 Chimeric Antigen Receptor Mouse T Cells Alone or Together With Anti-PD1 Antibody Inhibits the Growth of Mouse Breast Tumor Cells Expressing HER2 in vitro and in Immune Competent Mice.
The tumor-selective over-expression of the human Hsp70 gene is attributed to the aberrant controls at both initiation and elongation levels of transcription.
The use of recombinant adeno-associated viral vectors for the transduction of epithelial tumor cells.
The utility of the "Glowing Head" mouse for breast cancer metastasis research.
The vaccinia virus K1L gene product inhibits host NF-kappaB activation by preventing IkappaBalpha degradation.
Theaflavin, a black tea extract, is a novel anti-inflammatory compound.
Theranostic vitamin E TPGS micelles of transferrin conjugation for targeted co-delivery of docetaxel and ultra bright gold nanoclusters.
Therapeutic Improvement of a Stroma-Targeted CRAd by Incorporating Motives Responsive to the Melanoma Microenvironment.
Therapeutic Time-restricted Feeding Reduces Renal Tumor Bioluminescence in Mice but Fails to Improve Anti-CTLA-4 Efficacy.
Thermosensitive porphyrin-incorporated hydrogel with four-arm PEG-PCL copolymer (II): doxorubicin loaded hydrogel as a dual fluorescent drug delivery system for simultaneous imaging tracking in vivo.
Thermostability of firefly luciferases affects efficiency of detection by in vivo bioluminescence.
Thyroid hormone regulates the mouse thyrotropin beta-subunit gene promoter in transfected primary thyrotropes.
TMPRSS2-ERG fusions confer efficacy of enzalutamide in an in vivo bone tumor growth model.
TNFSF14, a novel target of miR-326, facilitates airway remodeling in airway smooth muscle cells via inducing extracellular matrix protein deposition and proliferation.
TNP1 Functional SNPs in bta-miR-532 and bta-miR-204 Target Sites Are Associated with Semen Quality Traits in Chinese Holstein Bulls.
Tracking leukemic T-cell transcriptional dynamics in vivo with a blood-based reporter assay.
Traditionally used Thai medicinal plants: In vitro anti-inflammatory, anticancer and antioxidant activities.
Traffic to lymph nodes of PC-3 prostate tumor cells in nude mice visualized using the luciferase gene as a tumor cell marker.
Transactivation of the IGFBP-2 promoter in human tumor cell lines.
Transcription of the human folylpoly-gamma-glutamate synthetase gene.
Transcriptional activation by p53 of the human type IV collagenase (gelatinase A or matrix metalloproteinase 2) promoter.
Transcriptional regulation of the rat steroidogenic acute regulatory protein gene by steroidogenic factor 1.
Transcriptional targeting of adenoviral vector through the CXCR4 tumor-specific promoter.
Transcriptional targeting of gene expression in breast cancer by the promoters of protein regulator of cytokinesis 1 and ribonuclease reductase 2.
Transcriptional targeting of tumors with a novel tumor-specific survivin promoter.
Transcriptionally targeted nonviral gene transfer using a beta-catenin/TCF-dependent promoter in a series of different human low passage colon cancer cells.
Transcriptomic analysis of hormone-sensitive patient-derived endometrial cancer spheroid culture defines Efp as a proliferation modulator.
Transduction of Tumor-Specific T Cells with CXCR2 Chemokine Receptor Improves Migration to Tumor and Antitumor Immune Responses.
Transgenic Animal Models to Visualize Cancer-Related Cellular Processes by Bioluminescence Imaging.
Transgenic mouse model expressing P53(R172H), luciferase, EGFP, and KRAS(G12D) in a single open reading frame for live imaging of tumor.
Treatment efficiency of a suicide gene therapy using prostate-specific membrane antigen promoter/enhancer in a castrated mouse model of prostate cancer.
Treatment of a human breast cancer xenograft with an adenovirus vector containing an interferon gene results in rapid regression due to viral oncolysis and gene therapy.
Treatment of leptomeningeal metastases in a rat model using a recombinant adenovirus containing the HSV-tk gene.
Tristetraprolin activation by resveratrol inhibits the proliferation and metastasis of colorectal cancer cells.
Tumor cell-derived TGF-beta and IL-10 dysregulate paclitaxel-induced macrophage activation.
Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity.
Tumor formation in a mouse model of colitis-associated colon cancer does not require COX-1 or COX-2 expression.
Tumor growth reduction and DNA transfer by cavitation-enhanced high-intensity focused ultrasound in vivo.
Tumor necrosis factor alpha-mediated tumor regression by the in vivo transfer of genes into the artery that leads to tumors.
Tumor necrosis factor-? regulates human follicular dendritic cell-secreted protein gene transcription in gingival epithelial cells.
Tumor Protein (TP)-p53 Members as Regulators of Autophagy in Tumor Cells upon Marine Drug Exposure.
Tumor regression and curability of preclinical neuroblastoma models by PEGylated SN38 (EZN-2208), a novel topoisomerase I inhibitor.
Tumor specific ultrasound enhanced gene transfer in vivo with novel liposomal bubbles.
Tumor suppressive microRNA?429 regulates cellular function by targeting VEGF in clear cell renal cell carcinoma.
Tumor suppressor microRNA-493 decreases cell motility and migration ability in human bladder cancer cells by downregulating RhoC and FZD4.
Tumor Suppressor Role of hsa-miR-193a-3p and -5p in Cutaneous Melanoma.
Tumor tissue characterization evaluating the luciferase activity under the control of a hsp70 promoter and MR imaging in three tumor cell lines.
Tumor-Specific Delivery of Immune Checkpoint Inhibitors by Engineered AAV Vectors.
Tumor-specific gene transfer with receptor-mediated nanocomplexes modified by polyethylene glycol shielding and endosomally cleavable lipid and peptide linkers.
Tumor-Specific, Hypoxia-Regulated WWOX Expression Adenovirus Inhibits Human Non-Small Cell Lung Cancer Growth in Vivo.
Tumor-targeted gene therapy for nasopharyngeal carcinoma.
Tumor-targeted gene therapy: strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes.
Twist1 and Y-box-binding protein-1 promote malignant potential in bladder cancer cells.
Ultrasound targeted microbubble destruction increases capillary permeability in hepatomas.
Up- and downregulation of mature miR-1587 function by modulating its G-quadruplex structure and using small molecules.
Up-regulation of miR-455-5p by the TGF-?-SMAD signalling axis promotes the proliferation of oral squamous cancer cells by targeting UBE2B.
UPF1 regulates the malignant biological behaviors of glioblastoma cells via enhancing the stability of Linc-00313.
Upregulation of microRNA-98 increases radiosensitivity in esophageal squamous cell carcinoma.
Upregulation of miR-144-3p expression attenuates glioma cell viability and invasion by targeting BCL6.
Upregulation of miR-215 attenuates propofol-induced apoptosis and oxidative stress in developing neurons by targeting LATS2.
Use of bioluminescent imaging to investigate the role of nuclear factor-kappaBeta in experimental non-small cell lung cancer metastasis.
Use of FVB Myc-CaP cells as an immune competent, androgen receptor positive, mouse model of prostate cancer bone metastasis.
Use of in vivo bioluminescence and MRI to determine hyperthermia-induced changes in luciferase activity under the control of an hsp70 promoter.
Use of mannosylated cationic liposomes/ immunostimulatory CpG DNA complex for effective inhibition of peritoneal dissemination in mice.
Use of transcription reporters with novel p53 binding sites to target tumour cells expressing endogenous or virally transduced p53 mutants with altered sequence-specificity.
Use of transient CD4 lymphocyte depletion to prolong transgene expression of E1-deleted adenoviral vectors.
Utilization of Ultrasound Guided Tissue-directed Cellular Implantation for the Establishment of Biologically Relevant Metastatic Tumor Xenografts.
Vaccinia as a vector for tumor-directed gene therapy: biodistribution of a thymidine kinase-deleted mutant.
Validating the use of a luciferase labeled breast cancer cell line, MDA435LCC6, as a means to monitor tumor progression and to assess the therapeutic activity of an established anticancer drug, docetaxel (Dt) alone or in combination with the ILK inhibitor, QLT0267.
Validation of bioluminescence imaging of colorectal liver metastases in the mouse.
Validity of bioluminescence measurements for noninvasive in vivo imaging of tumor load in small animals.
Variants in an Hdac9 intronic enhancer plasmid impact Twist1 expression in vitro.
Vectors based on reducible polycations facilitate intracellular release of nucleic acids.
Versatile and enhanced tumour modelling in mice via somatic cell transduction.
Virus-associated tumor imaging by induction of viral gene expression.
Visualization of hypoxia-inducible factor-1 transcriptional activation in C6 glioma using luciferase and sodium iodide symporter genes.
Xenotropic and polytropic retrovirus receptor 1 (XPR1) promotes progression of tongue squamous cell carcinoma (TSCC) via activation of NF-?B signaling.
Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol.
[Analysis of IL-8 gene transcription in human bronchial epithelial cells by stable transfection of a reporter gene]
[Application of secretary luciferase labeled orthotopic transplant model of hepatocellular carcinoma to evaluate tumor response to interferon-beta gene therapy].
[Balectin-3 affects the stability of vulnerable coronary atherosclerosis plaques by targeted modulation of lncARSR].
[Bioluminescent imaging: applications to cancerology and endocrinology]
[Construction and verification of NF-?B luciferase reporter gene system].
[Construction of an expression vector under the control of hTERT promoter.]
[Construction of human Egr-1 promoter and its response to ionizing radiation in tumor cells]
[Effect of GTPase activating protein Git2 on metastasis in breast cancer].
[Effect of SLC7A5 on the proliferation of tumor cells and its relationship with transforming growth factor-?1 ?signal pathway].
[Enhanced transduction efficiency of adeno-associated virus on cancer cells with the help of low dose adenovirus]
[Enhancement by hypoxia of antisense VEGF(165) gene expression in esophageal cancer cells]
[Establishment of a human bladder cancer cell line stably co-expressing hSPRY2 and luciferase genes and its subcutaneous tumor xenograft model in nude mice].
[Establishment of reporter gene-based assays for the identification of (anti) androgenic effects of chemicals in CHO cells]
[Establishment of the cell line that human lung adenocarcinoma can stably express luciferase which is absent of nm23-H1 expression and detecting its luminescence?in vitro and in vivo].
[Expression of Gluc-Fluc dual luciferase plasmid after transfection into MB49 bladder cells.]
[Expression of modified humanized immunoapoptotic protein and its specific killing effect on HER2-positive tumor cells].
[Mechanism and Clinical Significance of miR-373 In Elderly Patients with Multiple Myeloma].
[MicroRNA-218 promotes osteosarcoma cell apoptosis by down-regulating oncogene B lymphoma mouse Moloney leukemia virus insertion region 1].
[N-ethyl- and [N,N'-diethyl-1,2-bis(2,6-difluoro-3-hydroxyphenyl)-ethylenediamine]dichloroplatinum(II): structure and cytotoxic/estrogenic activity in breast cancer cells.
[Overexpression of miR-519d-3p inhibits the proliferation of DU-145 prostate cancer cells by reducing TRAF4].
[Proliferation of MicroRNA-365 and E74-like Factor 4 in Cervical Cancer Cells and Its Clinical Significance].
[Receptor mediated gene transfer in squamous epithelial carcinoma of the head-neck area]
[Study on the anti-tumor effect of paclitaxel mixed micelle by using in vivo optical imaging technique].
[Synthesis of GnRH analogs and their application in targeted gene delivery systems].
Neoplasms, Squamous Cell
Efficacy of transfection rates on head and neck squamous cell cancer by a novel adenovirus: an in vivo and in vitro study.
[Receptor mediated gene transfer in squamous epithelial carcinoma of the head-neck area]
Neoplastic Cells, Circulating
Mammographically dense human breast tissue stimulates MCF10DCIS.com progression to invasive lesions and metastasis.
Neural Tube Defects
Donor mesenchymal stem cell linetics after transamniotic stem cell therapy (TRASCET) for experimental spina bifida.
Neuralgia
LncRNA MALAT1 promotes neuropathic pain progression through the miR?154?5p/AQP9 axis in CCI rat models.
Neurilemmoma
A novel imaging-compatible sciatic nerve schwannoma model.
Regression of schwannomas induced by adeno-associated virus-mediated delivery of caspase-1.
Neuroblastoma
5-HT2C receptor gene polymorphisms associated with antipsychotic drug action alter promoter activity.
A Cell-Based High-Throughput Screen Addressing 3'UTR-Dependent Regulation of the MYCN Gene.
A direct regulatory link between microRNA-137 and SHANK2: implications for neuropsychiatric disorders.
A facile Friedel-Crafts acylation for the synthesis of polyethylenimine-grafted multi-walled carbon nanotubes as efficient gene delivery vectors.
A high-throughput drug screen targeted to the 5'untranslated region of Alzheimer amyloid precursor protein mRNA.
A neuroblastoma-selective suicide gene therapy approach using the tyrosine hydroxylase promoter.
A novel blood-brain barrier co-culture system for drug targeting of Alzheimer's disease: establishment by using acitretin as a model drug.
A novel doxycycline inducible autoregulatory plasmid which displays "on"/"off" regulation suited to gene therapy applications.
A novel quantitative high-throughput screen identifies drugs that both activate SUMO conjugation via the inhibition of microRNAs 182 and 183 and facilitate neuroprotection in a model of oxygen and glucose deprivation.
A rapid assay for glial cell line-derived neurotrophic factor and neurturin based on transfection of cells with tyrosine hydroxylase promoter-luciferase construct.
A single nucleotide polymorphism in the 3'UTR of the SNCA gene encoding alpha-synuclein is a new potential susceptibility locus for Parkinson disease.
alpha-Synuclein maps to a quantitative trait locus for alcohol preference and is differentially expressed in alcohol-preferring and -nonpreferring rats.
Alternative polyadenylation and miR-34 family members regulate tau expression.
An in vitro approach to test the possible role of candidate factors in the transcriptional regulation of the RET proto-oncogene.
Androgen receptor transcriptionally regulates ?-opioid receptor expression in rat trigeminal ganglia.
Calsenilin regulates presenilin 1/{gamma}-secretase-mediated N-cadherin {varepsilon}-cleavage and {beta}-catenin signaling.
Cell-specific expression of the rat secretogranin II promoter.
Central memory phenotype drives success of checkpoint inhibition in combination with CAR T cells.
Characterization of phorbolester-inducible human neuronal factors involved in trans-activation of the galanin gene.
Characterization of the rat connexin40 promoter: two Sp1/Sp3 binding sites contribute to transcriptional activation.
Cloning and characterization of the promoter region of the mouse mu opioid receptor gene.
Cloning and functional characterization of the murine caspase-3 gene promoter.
Cytoplasmic polyadenylation-element-binding protein (CPEB)1 and 2 bind to the HIF-1alpha mRNA 3'-UTR and modulate HIF-1alpha protein expression.
Differential effects of the HESR/HEY transcription factor family on dopamine transporter reporter gene expression via variable number of tandem repeats.
Differential expression and transcription factor binding associated with genotype at a pharmacogenetic variant in OPRD1.
Disruption of the MYC transcriptional function by a small-molecule antagonist of MYC/MAX dimerization.
Dorsal root ganglia neuron-specific promoter activity of the rabbit beta-galactoside alpha1,2-fucosyltransferase gene.
Down-regulation of the dopamine receptor D2 in mice lacking ataxin 1.
Downregulation of miRNA-134 protects neural cells against ischemic injury in N2A cells and mouse brain with ischemic stroke by targeting HSPA12B.
Effect of allelic variation at the NACP-Rep1 repeat upstream of the alpha-synuclein gene (SNCA) on transcription in a cell culture luciferase reporter system.
Effect of polymorphism on expression of the neuropeptide Y gene in inbred alcohol-preferring and -nonpreferring rats.
Engineering viral promoters for gene transfer to human neuroblasts.
Ets1 transcription factor mediates gastrin-releasing peptide-induced IL-8 regulation in neuroblastoma cells.
Evaluation of chemical modification effects on DNA plasmid transfection efficiency of single-walled carbon nanotube-succinate- polyethylenimine conjugates as non-viral gene carriers.
Evidence for an internal regulatory region in a human nonmuscle myosin heavy chain gene.
Exonic Sp1 sites are required for neural-specific expression of the glycine receptor beta subunit gene.
Extracts of Fruits and Vegetables Activate the Antioxidant Response Element in IMR-32 Cells.
FDA-preapproved drugs targeted to the translational regulation and processing of the amyloid precursor protein.
Functional assessment of a promoter polymorphism in S100B, a putative risk variant for bipolar disorder.
Gene structure of the human metabotropic glutamate receptor 5 and functional analysis of its multiple promoters in neuroblastoma and astroglioma cells.
Gene transfer efficiency of high primary amine content, hydrophobic, alkyl-oligoamine derivatives of polyethylenimine.
Genetic variability in the regulatory region of presenilin 1 associated with risk for Alzheimer's disease and variable expression.
Genomic organization of alpha1 and beta1 subunits of the mammalian soluble guanylyl cyclase genes.
Genomic structure and promoter activity of the mouse polysialic acid synthase (mST8Sia IV/PST) gene.
Genomic variations and transcriptional regulation of the human mu-opioid receptor gene.
Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinase.
Glucocorticoid and androgen activation of monoamine oxidase A is regulated differently by R1 and Sp1.
Homocysteine regulates expression of Herp by DNA methylation involving the AARE and CREB binding sites.
Hsa-miR-376c-3p targets Cyclin D1 and induces G1-cell cycle arrest in neuroblastoma cells.
Identification and functional characterisation of a novel dopamine beta hydroxylase gene variant associated with attention deficit hyperactivity disorder.
Identification of an RB-responsive region in the 5' untranslated region of the RB gene.
Identification of GLI Mutations in Patients With Hirschsprung Disease That Disrupt Enteric Nervous System Development in Mice.
Identification of the promoter region and the 5'-untranslated exons of the human voltage-gated sodium channel Na(v)1.1 gene (SCN1A) and enhancement of gene expression by the 5'-untranslated exons.
Identifying the promoter region of the human brain sodium channel subtype II gene (SCN2A).
Improved gene transfer to neuroblastoma cells by a monoclonal antibody targeting RET, a receptor tyrosine kinase.
Induction of apoptosis in murine neuroblastoma by systemic delivery of transferrin-shielded siRNA polyplexes for downregulation of Ran.
Induction of parkin expression in the presence of oxidative stress.
INSM1 Promoter-Driven Adenoviral Herpes Simplex Virus Thymidine Kinase Cancer Gene Therapy for the Treatment of Primitive Neuroectodermal Tumors.
Integrin-targeted nanocomplexes for tumour specific delivery and therapy by systemic administration.
Isolation and characterization of the 5´-upstream region of the human voltage-gated Ca(2+) channel ? (2)?-1 auxiliary subunit gene: promoter analysis and regulation by transcription factor Sp1.
Isolation and characterization of the mouse PDGF beta-receptor promoter.
Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery.
Mesenchymal stem cells accelerated growth and metastasis of neuroblastoma and preferentially homed towards both primary and metastatic loci in orthotopic neuroblastoma model.
Micro-RNA-137 Inhibits Tau Hyperphosphorylation in Alzheimer's Disease and Targets the CACNA1C Gene in Transgenic Mice and Human Neuroblastoma SH-SY5Y Cells.
MicroRNA-204 increases sensitivity of neuroblastoma cells to cisplatin and is associated with a favourable clinical outcome.
Modified polyethyleneimine with histidine-lysine short peptides as gene carrier.
Molecular Function Analysis of Rabies Virus RNA Polymerase L Protein by Using an L Gene-Deficient Virus.
Multimodal imaging analysis of tumor progression and bone resorption in a murine cancer model.
Nanoparticles of compacted DNA transfect postmitotic cells.
NEAT1 Negatively Regulates Cell Proliferation and Migration of Neuroblastoma Cells by miR-183-5p/FOXP1 Via the ERK/AKT Pathway.
Neuroprotective agent chlomethiazole attenuates c-fos, c-jun, and AP-1 activation through inhibition of p38 MAP kinase.
Nuclear localization signal peptides enhance cationic liposome-mediated gene therapy.
Overexpression of PrPC by adenovirus-mediated gene targeting reduces ischemic injury in a stroke rat model.
Pharmacological profile of brain-derived neurotrophic factor (BDNF) splice variant translation using a novel drug screening assay: a "quantitative code".
Post-translational regulation of gene expression using the ATF4 oxygen-dependent degradation domain for hypoxia-specific gene therapy.
PPP2R2B CAG repeat length in the Han Chinese in Taiwan: Association analyses in neurological and psychiatric disorders and potential functional implications.
Promoter analysis of human corticotropin-releasing factor (CRF) type 1 receptor and regulation by CRF and urocortin.
Promoter variant in the GRK3 gene associated with bipolar disorder alters gene expression.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Receptor-targeted liposome-peptide nanocomplexes for siRNA delivery.
SCA8 repeat expansion: large CTA/CTG repeat alleles in neurological disorders and functional implications.
Sp1 and Sp3 activate the rat connexin40 proximal promoter.
Sp1-binding elements in the promoter of RAGE are essential for amphoterin-mediated gene expression in cultured neuroblastoma cells.
Structural and functional characterization of the human alpha3 nicotinic subunit gene promoter.
Targeted suicide gene transfections reveal promising results in nu/nu mice with aggressive neuroblastoma.
Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition.
The genomic structure and promoter region of the human parkin gene.
The MYCN oncoprotein as a drug development target.
The neurogene BTG2TIS21/PC3 is transactivated by DeltaNp73alpha via p53 specifically in neuroblastoma cells.
The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma.
The purinergic P2Y(13) receptor activates the Nrf2/HO-1 axis and protects against oxidative stress-induced neuronal death.
The thyrotropin-releasing hormone gene 1998: cloning, characterization, and transcriptional regulation in the central nervous system, heart, and testis.
Tissue-specific expression of a suicide gene for selective killing of neuroblastoma cells using a promoter region of the NCX gene.
Transcription factor cyclic adenosine monophosphate responsive element binding protein negatively regulates tumor necrosis factor alpha-induced protein 1 expression.
Transcription of the mouse mu-opioid receptor gene is regulated by two promoters.
Transcriptional regulation of the human alpha1a-adrenergic receptor gene. Characterization Of the 5'-regulatory and promoter region.
Tumor regression and curability of preclinical neuroblastoma models by PEGylated SN38 (EZN-2208), a novel topoisomerase I inhibitor.
Tumor-specific gene transfer with receptor-mediated nanocomplexes modified by polyethylene glycol shielding and endosomally cleavable lipid and peptide linkers.
Upregulation of the neuron-specific K+/Cl- cotransporter expression by transcription factor early growth response 4.
Valproate robustly enhances AP-1 mediated gene expression.
VIP receptor 1 (VPAC1) promoter targets the expression of a reporter gene to cerebellum and adrenal medulla in transgenic mice.
Winged helix hepatocyte nuclear factor 3 and POU-domain protein brn-2/N-oct-3 bind overlapping sites on the neuronal promoter of human aromatic L-amino acid decarboxylase gene.
Neurodegenerative Diseases
Untying a nanoscale knotted polymer structure to linear chains for efficient gene delivery in vitro and to the brain.
Neuroendocrine Tumors
Multiple Endocrine Neoplasia Type 1 (MEN1) 5'UTR Deletion, in MEN1 Family, Decreases Menin Expression.
Neurofibromatoses
A novel imaging-compatible sciatic nerve schwannoma model.
LukS-PV-Regulated MicroRNA-125a-3p Promotes THP-1 Macrophages Differentiation and Apoptosis by Down-Regulating NF1 and Bcl-2.
Neurofibromatosis 1
LukS-PV-Regulated MicroRNA-125a-3p Promotes THP-1 Macrophages Differentiation and Apoptosis by Down-Regulating NF1 and Bcl-2.
Neurofibromatosis 2
A novel imaging-compatible sciatic nerve schwannoma model.
Neurofibrosarcoma
MLN8237 treatment in an orthoxenograft murine model for malignant peripheral nerve sheath tumors.
Tumor targeted delivery of doxorubicin in malignant peripheral nerve sheath tumors.
Neuroinflammatory Diseases
Anti-inflammatory effects of astroglial ?7 nicotinic acetylcholine receptors are mediated by inhibition of the NF-?B pathway and activation of the Nrf2 pathway.
LncRNA MALAT1 promotes neuropathic pain progression through the miR?154?5p/AQP9 axis in CCI rat models.
Molecular imaging of nestin in neuroinflammatory conditions reveals marked signal induction in activated microglia.
Nevus
Antitumor activity of miR-1280 in melanoma by regulation of Src.
Newcastle Disease
N(pro) of classical swine fever virus is an antagonist of double-stranded RNA-mediated apoptosis and IFN-alpha/beta induction.
Non-alcoholic Fatty Liver Disease
CYP3A Activity and Expression in Nonalcoholic Fatty Liver Disease.
miR-222 targets ACOX1, promotes triglyceride accumulation in hepatocytes.
Noonan Syndrome
Gain-of-function mutations in RIT1 cause Noonan syndrome, a RAS/MAPK pathway syndrome.
Obesity
Impact of REV-ERB alpha gene polymorphisms on obesity phenotypes in adult and adolescent samples.
Oligodendroglioma
Ceramide galactosyltransferase expression is regulated positively by Nkx2.2 and negatively by OLIG2.
Isolation, sequencing, and functional analysis of the TATA-less human ATPase II promoter.
Oncogene Addiction
Illuminating cancer systems with genetically engineered mouse models and coupled luciferase reporters in vivo.
Osteoarthritis
A novel Saa3-promoter reporter distinguishes inflammatory subtypes in experimental arthritis and human synovial fibroblasts.
The function of microRNA-34a in osteoarthritis.
Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation.
Trex-1 deficiency in rheumatoid arthritis synovial fibroblasts.
Osteolysis
Triptolide inhibits osteoclast formation, bone resorption, RANKL-mediated NF-?B activation and titanium particle-induced osteolysis in a mouse model.
Osteoporosis
Estrogenic effects of herbal medicines from Costa Rica used for the management of menopausal symptoms.
MicroRNA-135a-5p is involved in osteoporosis progression through regulation of osteogenic differentiation by targeting RUNX2.
miR-485-5p promotes osteoporosis via targeting Osterix.
miR?27a?3p negatively regulates osteogenic differentiation of MC3T3?E1 preosteoblasts by targeting osterix.
Overexpression of miR125b Promotes Osteoporosis Through miR-125b-TRAF6 Pathway in Postmenopausal Ovariectomized Rats.
Osteosarcoma
A highly sensitive method for large-scale measurements of 1,25-dihydroxyvitamin D.
A mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by Luciferase imaging.
ADRA2A is involved in neuro-endocrine regulation of bone resorption.
Advantages of bioluminescence imaging to follow siRNA or chemotherapeutic treatments in osteosarcoma preclinical models.
An orthotopic, postsurgical model of luciferase transfected murine osteosarcoma with spontaneous metastasis.
Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/beta-catenin antagonists against human osteosarcoma cells.
Circular RNA GLI2 promotes osteosarcoma cell proliferation, migration, and invasion by targeting miR-125b-5p.
Compactin and simvastatin, but not pravastatin, induce bone morphogenetic protein-2 in human osteosarcoma cells.
Do Mesenchymal Stromal Cells Influence Microscopic Residual or Metastatic Osteosarcoma in a Murine Model?
Dysregulation of microRNA-106a-5p-RUNX1 axis associates with clinical progression and prognosis of osteosarcoma patients.
E2F1 silencing inhibits migration and invasion of osteosarcoma cells via regulating DDR1 expression.
Effect of CXCR4 on Apoptosis in Osteosarcoma Cells via the PI3K/Akt/NF-?? Signaling Pathway.
Effects of caffeine on the human circadian clock in vivo and in vitro.
Effects of Maerua subcordata (Gilg) DeWolf on electrophile-responsive element (EpRE)-mediated gene expression in vitro.
Elevated expression of microRNA-328-3p suppresses aggressive malignant behaviors via targeting matrix metalloprotease 16 in osteosarcoma.
Estrogenic properties of naturally occurring prenylated isoflavones in U2OS human osteosarcoma cells: Structure-activity relationships.
Functional imaging of multidrug resistance in an orthotopic model of osteosarcoma using (99m)Tc-sestamibi.
G-quadruplex formation in the Oct4 promoter positively regulates Oct4 expression.
High Content Screening Using New U2OS Reporter Cell Models Identifies Harmol Hydrochloride as a Selective and Competitive Antagonist of the Androgen Receptor.
Highly metastatic K7M2 cell line: A novel murine model capable of in vivo imaging via luciferase vector transfection.
Hsa-let-7g promotes osteosarcoma by reducing HOXB1 to activate NF-kB pathway.
Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor.
Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors.
IGFBP-3 stimulates human osteosarcoma cell migration by upregulating VCAM-1 expression.
LncRNA MALAT1 Promotes Cancer Metastasis in Osteosarcoma via Activation of the PI3K-Akt Signaling Pathway.
MicroRNA-1 functions as a potential tumor suppressor in osteosarcoma by targeting Med1 and Med31.
MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene in human hepatocellular carcinoma.
MicroRNA-132 inhibits cell growth and metastasis in osteosarcoma cell lines possibly by targeting Sox4.
MicroRNA-16 suppressed the invasion and migration of osteosarcoma by directly inhibiting RAB23.
MicroRNA-212 suppresses the proliferation and migration of osteosarcoma cells by targeting forkhead box protein A1.
MicroRNA-214 functions as an oncogene in human osteosarcoma by targeting TRAF3.
MicroRNA-27a functions as an oncogene in human osteosarcoma by targeting CCNG1.
MicroRNA-302a inhibits osteosarcoma cell migration and invasion by directly targeting IGF-1R.
MicroRNA-31 inhibits osteosarcoma cell proliferation, migration and invasion by targeting PIK3C2A.
MicroRNA-505 is downregulated in human osteosarcoma and regulates cell proliferation, migration and invasion.
MicroRNA-524 promotes cell proliferation by down-regulating PTEN expression in osteosarcoma.
MicroRNA-603 functions as an oncogene by suppressing BRCC2 protein translation in osteosarcoma.
microRNA-96 acts as a tumor suppressor gene in human osteosarcoma via target regulation of EZRIN.
MicroRNA?106a regulates the proliferation and invasion of human osteosarcoma cells by targeting VNN2.
MicroRNA?643 regulates the expression of ZEB1 and inhibits tumorigenesis in osteosarcoma.
miR-134 inhibits osteosarcoma cell invasion and metastasis through targeting MMP1 and MMP3 in vitro and in vivo.
miR-210 promotes human osteosarcoma cell migration and invasion by targeting FGFRL1.
miR-33a Mediates the Anti-Tumor Effect of Lovastatin in Osteosarcoma by Targeting CYR61.
MiR-33b inhibits osteosarcoma cell proliferation through suppression of glycolysis by targeting Lactate Dehydrogenase A (LDHA).
MiR-429 suppresses the progression and metastasis of osteosarcoma by targeting ZEB1.
miR-454 is down-regulated in osteosarcomas and suppresses cell proliferation and invasion by directly targeting c-Met.
miR-627-3p inhibits osteosarcoma cell proliferation and metastasis by targeting PTN.
miRNA-646 suppresses osteosarcoma cell metastasis by downregulating fibroblast growth factor 2 (FGF2).
Molecular cloning of the murine PHEX gene promoter.
Non-invasive imaging of engineered human tumors in the living chicken embryo.
Novel ring A stereoisomers of 2-methyl-1alpha,25-dihydroxyvitamin D(3) and 2-methyl-20-epi-1alpha,25-dihydroxyvitamin D(3): transactivation of target genes and modulation of differentiation in human promyelocytic leukemia (HL-60) cells.
Nuclear Innate Immune DNA Sensor IFI16 Is Degraded during Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV): Role of IFI16 in Maintenance of KSHV Latency.
Oleocanthal Modulates Estradiol-Induced Gene Expression Involving Estrogen Receptor ?.
Osteoporosis genome-wide association study variant c.3781 C>A is regulated by a novel anti-osteogenic factor miR-345-5p.
Overexpression of miR-329-3p sensitizes osteosarcoma cells to cisplatin through suppression of glucose metabolism by targeting LDHA.
Silica nanoparticles and polyethyleneimine (PEI)-mediated functionalization: a new method of PEI covalent attachment for siRNA delivery applications.
Targeted expression of human folylpolyglutamate synthase for selective enhancement of methotrexate chemotherapy in osteosarcoma cells.
Targeted gene delivery to human osteosarcoma cells with magnetic cationic liposomes under a magnetic field.
The tumor-suppressive microRNA-135b targets c-myc in osteoscarcoma.
TNF-? mediates the stimulation of sclerostin expression in an estrogen-deficient condition.
Tumor necrosis factor-related apoptosis-inducing ligand induces cytotoxicity specific to osteosarcoma by microRNA response elements.
Using the Spleen as an In Vivo Systemic Immune Barometer Alongside Osteosarcoma Disease Progression and Immunotherapy with ?-PD-L1.
Zoledronic Acid Inhibits Both the Osteolytic and Osteoblastic Components of Osteosarcoma Lesions in a Mouse Model.
[Long non-coding RNA RAB11B-AS1 prevents osteosarcoma proliferation via its sense gene RAB11B].
[microRNA-181b promotes migration and invasion of osteosarcoma cells by targeting N-myc downstream regulated gene 2].
[miR-181a promotes the proliferation and metastasis of osteosarcoma cells by targeting RASSF1A].
[MiR-300 inhibits invasion and metastasis of osteosarcoma cell MG63 by negatively regulating PTTG1].
[Structural characterization of 5' flanking regulatory region of DNA repair gene Rad51]
Ovarian Neoplasms
A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and ?-catenin-ABCG2 signaling.
An advanced generation of adenoviral vectors selectively enhances gene transfer for ovarian cancer gene therapy approaches.
An Orthotopic Mouse Model of Ovarian Cancer using Human Stroma to Promote Metastasis.
Anticancer activity of the intraperitoneal-delivered DFP-10825, the cationic liposome-conjugated RNAi molecule targeting thymidylate synthase, on peritoneal disseminated ovarian cancer xenograft model.
Apolipoprotein A-I mimetic peptides inhibit expression and activity of hypoxia-inducible factor-1? in human ovarian cancer cell lines and a mouse ovarian cancer model.
Aurora-A/SOX8/FOXK1 signaling axis promotes chemoresistance via suppression of cell senescence and induction of glucose metabolism in ovarian cancer organoids and cells.
c-Fos mediates ?1, 2-fucosyltransferase 1 and Lewis y expression in response to TGF-?1 in ovarian cancer.
Cancer immunotherapy using irradiated tumor cells secreting heat shock protein 70.
circEPSTI1 regulates ovarian cancer progression via decoying miR-942.
circGFRA1 Promotes Ovarian Cancer Progression By Sponging miR-449a.
CircRNA_100395 inhibits cell proliferation and metastasis in ovarian cancer via regulating miR-1228/p53/epithelial-mesenchymal transition (EMT) axis.
Conditionally replicating adenovirus expressing TIMP2 increases survival in a mouse model of disseminated ovarian cancer.
Confirmation of 42-bp deletion within the ERCC1 5' UTR.
Cucurbit [7] uril encapsulated cisplatin overcomes resistance to cisplatin induced by Rab25 overexpression in an intraperitoneal ovarian cancer model.
Demethoxycurcumin inhibited human epithelia ovarian cancer cells' growth via up-regulating miR-551a.
Development of a clinically relevant ovarian cancer model incorporating surgical cytoreduction to evaluate treatment of micro-metastatic disease.
Exploring the HYDRAtion method for loading siRNA on liposomes: the interplay between stability and biological activity in human undiluted ascites fluid.
Generation of a syngeneic mouse model to study the intraperitoneal dissemination of ovarian cancer with in vivo luciferase imaging.
Hypoxia-induced elevation in interleukin-8 expression by human ovarian carcinoma cells.
Imaging CXCL12-CXCR4 signaling in ovarian cancer therapy.
In vitro expression of the diphtheria toxin A-chain gene under the control of human chorionic gonadotropin gene promoters as a means of directing toxicity to ovarian cancer cell lines.
Knockdown of NRSF inhibits cell proliferation of ovarian cancer via activating Hippo pathway.
LINC00339 promotes cell proliferation, migration, and invasion of ovarian cancer cells via miR-148a-3p/ROCK1 axes.
LNC00115 Mediates Cisplatin Resistance by Regulating the miR-7/ERK Signalling Pathway in Ovarian Cancer.
lncRNA HEIH accelerates cell proliferation and inhibits cell senescence by targeting miR-3619-5p/CTTNBP2 axis in ovarian cancer.
LncRNA LINC00857 regulates the progression and glycolysis in ovarian cancer by modulating the Hippo signaling pathway.
LncRNA-ATB Promotes the Tumorigenesis of Ovarian Cancer via Targeting miR-204-3p.
lncRNA-PRLB Confers Paclitaxel Resistance of Ovarian Cancer Cells by Regulating RSF1/NF-?B Signaling Pathway.
Long noncoding RNA DARS-AS1 acts as an oncogene by targeting miR-532-3p in ovarian cancer.
Mechanism of vascular endothelial growth factor expression mediated by cisplatin in human ovarian cancer cells.
microRNA-137 promotes apoptosis in ovarian cancer cells via the regulation of XIAP.
MicroRNA-149 suppresses the proliferation and increases the sensitivity of ovarian cancer cells to cisplatin by targeting X-linked inhibitor of apoptosis.
MicroRNA-365 inhibits ovarian cancer progression by targeting Wnt5a.
MicroRNAs 125a and 125b inhibit ovarian cancer cells through post-transcriptional inactivation of EIF4EBP1.
miR-1224-5p inhibits the proliferation and invasion of ovarian cancer via targeting SND1.
MiR-125a regulates ovarian cancer proliferation and invasion by repressing GALNT14 expression.
MiR-126-3p inhibits ovarian cancer proliferation and invasion via targeting PLXNB2.
miR-152 is involved in the proliferation and metastasis of ovarian cancer through repression of ERBB3.
miR-197-3p reduces epithelial-mesenchymal transition by targeting ABCA7 in ovarian cancer cells.
miR-362-3p acts as a tumor suppressor by targeting SERBP1 in ovarian cancer.
MiR-4429 suppresses the malignant development of ovarian cancer by targeting YOD1.
MiR-548c impairs migration and invasion of endometrial and ovarian cancer cells via downregulation of Twist.
miR-552 promotes ovarian cancer progression by regulating PTEN pathway.
MiR-760 overexpression promotes proliferation in ovarian cancer by downregulation of PHLPP2 expression.
MiR-92 overexpression suppresses immune cell function in ovarian cancer via LATS2/YAP1/PD-L1 pathway.
miR-92a Inhibits Peritoneal Dissemination of Ovarian Cancer Cells by Inhibiting Integrin ?5 Expression.
Overexpressed miR-9 promotes tumor metastasis via targeting E-cadherin in serous ovarian cancer.
Overexpression of PTEN in ovarian cancer cells suppresses i.p. dissemination and extends survival in mice.
P18/Stathmin1 is regulated by miR-31 in ovarian cancer in response to taxane.
Propofol?induced miR?125a?5p inhibits the proliferation and metastasis of ovarian cancer by suppressing LIN28B.
Qualitative in vivo bioluminescence imaging.
RHPN2 Promotes Malignant Cell Behaviours in Ovarian Cancer by Activating STAT3 Signalling.
Selective activation of ceruloplasmin promoter in ovarian tumors: potential use for gene therapy.
Silencing LGR6 Attenuates Stemness and Chemoresistance via Inhibiting Wnt/?-Catenin Signaling in Ovarian Cancer.
SLC27A2 regulates miR-411 to affect chemo-resistance in ovarian cancer.
Specific thiazolidinediones inhibit ovarian cancer cell line proliferation and cause cell cycle arrest in a PPAR? independent manner.
STAT3 regulated miR-216a promotes ovarian cancer proliferation and cisplatin resistance.
Targeting miR-21-3p inhibits proliferation and invasion of ovarian cancer cells.
The activity of a novel mithramycin analog is related to its binding to DNA, cellular accumulation, and inhibition of Sp1-driven gene transcription.
The dark side of ID8-Luc2: pitfalls for luciferase tagged murine models for ovarian cancer.
The oncogenic Golgi phosphoprotein 3 like overexpression is associated with cisplatin resistance in ovarian carcinoma and activating the NF-?B signaling pathway.
The oncoprotein hepatitis B X-interacting protein promotes the migration of ovarian cancer cells through the upregulation of S-phase kinase-associated protein 2 by Sp1.
Transcriptional targeting in ovarian cancer cells using the human epididymis protein 4 promoter.
Transcriptional targeting of adenoviral vector through the CXCR4 tumor-specific promoter.
Up-regulation of miR-383-5p suppresses proliferation and enhances chemosensitivity in ovarian cancer cells by targeting TRIM27.
VEGF- and LPA-induced telomerase in human ovarian cancer cells is Sp1-dependent.
ZNF703 promotes tumor progression in ovarian cancer by interacting with HE4 and epigenetically regulating PEA15.
[Effect of miR-145 on Migration and Invasion of Ovarian Cancer Cells].
[Involvement of miR-199a in cisplatin resistance of ovarian cancer cell through modulating expression of mTOR].
Pancreatic Diseases
MicroRNA?224 is downregulated in mucinous cystic neoplasms of the pancreas and may regulate tumorigenesis by targeting Jagged1.
Pancreatic Neoplasms
1,2,3-Triazolyl ester of ketorolac (15K), a potent PAK1 blocker, inhibits both growth and metastasis of orthotopic human pancreatic cancer xenografts in mice.
Adaptation of vectors and drug-inducible systems for controlled expression of transgenes in the tumor microenvironment.
Clinicopathological significance and molecular regulation of maspin expression in ductal adenocarcinoma of the pancreas.
Conditionally replicative adenoviral vectors for imaging the effect of chemotherapy on pancreatic cancer cells.
Dominant negative MEKK1 inhibits survival of pancreatic cancer cells.
Downregulation of miR?29b targets DNMT3b to suppress cellular apoptosis and enhance proliferation in pancreatic cancer.
Downregulation of survivin by siRNA diminishes radioresistance of pancreatic cancer cells.
Effect of cromolyn on S100P interactions with RAGE and pancreatic cancer growth and invasion in mouse models.
Effect of Plasma-Activated Lactated Ringer's Solution on Pancreatic Cancer Cells In Vitro and In Vivo.
Essential contribution of Ets-1 to constitutive Pim-3 expression in human pancreatic cancer cells.
Few genes are associated with the capability of pancreatic ductal adenocarcinoma cells to grow in the liver of nude rats.
FH535 inhibited metastasis and growth of pancreatic cancer cells.
Hypoxia-Inducible Factor-1? Regulates Chemotactic Migration of Pancreatic Ductal Adenocarcinoma Cells through Directly Transactivating the CX3CR1 Gene.
In vivo bioluminescent imaging of irradiated orthotopic pancreatic cancer xenografts in nonobese diabetic-severe combined immunodeficient mice: a novel method for targeting and assaying efficacy of ionizing radiation.
Inhibitory activity of flavonoids from Ephedrae Herba on hypoxia signaling in PANC-1 cells and the evaluation of their mechanisms.
Leucine-zipper protein, LDOC1, inhibits NF-kappaB activation and sensitizes pancreatic cancer cells to apoptosis.
LINC00052 functions as a tumor suppressor through negatively modulating miR-330-3p in pancreatic cancer.
LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis.
Mechanism of miR-210 involved in epithelial-mesenchymal transition of pancreatic cancer cells under hypoxia.
Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death.
MicroRNA-138-5p regulates pancreatic cancer cell growth through targeting FOXC1.
MicroRNA-202 suppresses glycolysis of pancreatic cancer by targeting hexokinase 2.
MicroRNA-mediated regulation of pancreatic cancer cell proliferation.
MicroRNA?296 targets AKT2 in pancreatic cancer and functions as a potential tumor suppressor.
MiR-130b Is a Prognostic Marker and Inhibits Cell Proliferation and Invasion in Pancreatic Cancer through Targeting STAT3.
miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor.
MiR-29b suppresses proliferation and mobility by targeting SOX12 and DNMT3b in pancreatic cancer.
miR-30d suppresses proliferation and invasiveness of pancreatic cancer by targeting the SOX4/PI3K-AKT axis and predicts poor outcome.
MiR-608 regulating the expression of ribonucleotide reductase M1 and cytidine deaminase is repressed through induced gemcitabine chemoresistance in pancreatic cancer cells.
Modulation of Pancreatic Cancer Chemoresistance by Inhibition of TAK1.
Nanoparticulate delivery of diphtheria toxin DNA effectively kills Mesothelin expressing pancreatic cancer cells.
Oncogenic TRIM31 confers gemcitabine resistance in pancreatic cancer via activating the NF-?B signaling pathway.
Overexpression of membrane-type 2 matrix metalloproteinase induced by hypoxia-inducible factor-1? in pancreatic cancer: Implications for tumor progression and prognosis.
Potential tumor-targeting peptide vector of histidylated oligolysine conjugated to a tumor-homing RGD motif.
Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells.
RNA interference may be more potent than antisense RNA in human cancer cell lines.
Rosmarinic inhibits cell proliferation, invasion and migration via up-regulating miR-506 and suppressing MMP2/16 expression in pancreatic cancer.
Selective Killing of Hypoxia-Inducible Factor-1-Active Cells Improves Survival in a Mouse Model of Invasive and Metastatic Pancreatic Cancer.
Simultaneous inhibition of multiple oncogenic miRNAs by a multi-potent microRNA sponge.
STIM1 overexpression in hypoxia microenvironment contributes to pancreatic carcinoma progression.
Targeted therapy of spontaneous murine pancreatic tumors by polymeric micelles prolongs survival and prevents peritoneal metastasis.
The interaction between miR?148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer.
Transcriptional regulation of urokinase-type plasminogen activator receptor by hypoxia-inducible factor 1 is crucial for invasion of pancreatic and liver cancer.
Pancreatitis
Systemic nf-kappaB activation in a transgenic mouse model of acute pancreatitis.
Pancreatitis, Acute Necrotizing
Differential response of the Senegalese sole (Solea senegalensis) Mx promoter to viral infections in two salmonid cell lines.
Papilloma
Cox-2 gene expression in chemically induced skin papillomas cannot predict subsequent tumor fate.
Non-invasive
Transcriptional repression of catalase in mouse skin tumor progression.
Papillomavirus Infections
Impact of inhibitors and L2 antibodies upon the infectivity of diverse alpha and beta human papillomavirus types.
Paralysis
Targeted foreign gene expression in spinal cord neurons using poliovirus replicons.
Paramyxoviridae Infections
Identification of two essential aspartates for polymerase activity in parainfluenza virus L protein by a minireplicon system expressing secretory luciferase.
Parasitemia
4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection.
Impact of Extended Duration of Artesunate Treatment on Parasitological Outcome in a Cytocidal Murine Malaria Model.
Parasitic Diseases
Luciferase Immunoprecipitation System Assay, a Rapid, Simple, Quantitative, and Highly Sensitive Antibody Detection for Parasitic Diseases.
Parathyroid Neoplasms
miR-129 Blocks Secondary Hyperparathyroidism-Inducing Fgf23/?Klotho Signaling in Mice with Chronic Kidney Disease.
Paratuberculosis
Detection of viable Mycobacterium avium subsp. paratuberculosis using luciferase reporter systems.
Development of a firefly luciferase-based assay for determining antimicrobial susceptibility of Mycobacterium avium subsp. paratuberculosis.
Development of luminescent Mycobacterium avium subsp. paratuberculosis for rapid screening of vaccine candidates in mice.
Genetic resistance of mice to Mycobacterium paratuberculosis is influenced by Slc11a1 at the early but not at the late stage of infection.
Phage infection, transfection and transformation of Mycobacterium avium complex and Mycobacterium paratuberculosis.
Parkinson Disease
Sevoflurane anesthesia represses neurogenesis of hippocampus neural stem cells via regulating microRNA-183-mediated NR4A2 in newborn rats.
Pemphigoid, Bullous
Calcineurin/NFAT-dependent regulation of 230-kDa bullous pemphigoid antigen (BPAG1) gene expression in normal human epidermal keratinocytes.
Keratinocyte responsive element 3: analysis of a keratinocyte-specific regulatory sequence in the 230-kDa bullous pemphigoid antigen gene promoter.
Periodontitis
Visualization of Oxidative Stress Induced by Experimental Periodontitis in Keap1-Dependent Oxidative Stress Detector-Luciferase Mice.
Peritoneal Fibrosis
MicroRNA-145 promotes the epithelial-mesenchymal transition in peritoneal dialysis-associated fibrosis by suppressing fibroblast growth factor 10.
Peritoneal Neoplasms
Atelocollagen-mediated in vivo siRNA transfection in ovarian carcinoma is influenced by tumor site, siRNA target and administration route.
Novel, genetically induced mouse model that recapitulates the histological morphology and immunosuppressive tumor microenvironment of metastatic peritoneal carcinomatosis.
Peritonitis
Peritonitis activates transcription of the human prolactin locus in myeloid cells in a humanized transgenic rat model.
Persistent Infection
[The sensitivity of transmitted/founder HIV-1 to anti-HIV drugs].
Peste-des-Petits-Ruminants
Paradigm shift in the diagnosis of peste des petits ruminants: scoping review.
Specific detection of peste des petits ruminants virus antibodies in sheep and goat sera by the luciferase immunoprecipitation system.
Pheochromocytoma
Cell-specific expression of the rat secretogranin II promoter.
Characterization of the 5'-flanking region of the rat TIS11 gene.
Characterization of two mouse models of metastatic pheochromocytoma using bioluminescence imaging.
Cloning and characterization of the rat TIS11 gene.
Differentiation of PC12 cells by infection with an HSV-1 vector expressing nerve growth factor.
Functional analysis of the proximal 5'-flanking region of the N-methyl-D-aspartate receptor subunit gene, NMDAR1.
Identification of a novel variant of the human NR2B gene promoter region and its possible association with schizophrenia.
Identification of a promoter region in the rat prion protein gene.
Induction of NFAT-mediated transcription by Gq-coupled receptors in lymphoid and non-lymphoid cells.
Promoter polymorphisms regulating corticotrophin-releasing hormone transcription in vitro.
Sequence variants of the CRH 5'-flanking region: effects on DNA-protein interactions studied by EMSA in PC12 cells.
Transcription of the rat angiotensin II type 2 receptor gene.
Transcriptional activation function of zinc finger protein TIS11 and its negative regulation by phorbol ester.
Transcriptional regulation of the mouse angiotensin II type 2 receptor gene.
Photophobia
Novel luciferase-opsin combinations for improved luminopsins.
Pituitary Neoplasms
Caveolin-1 promotes pituitary adenoma cells migration and invasion by regulating the interaction between EGR1 and KLF5.
Clustered point mutation analysis of the rat prolactin promoter.
Continuous measurement of targeted promoter activity by a secreted bioluminescence reporter, Vargula hilgendorfii luciferase.
Detection of thyroid hormone receptor disruptors by a novel stable in vitro reporter gene assay.
Enhancement of proopiomelanocortin gene promoter activity by local anesthetics in a pituitary cell line.
Expression of somatostatin receptor subtype 2 in growth hormone-secreting pituitary adenoma and the regulation of miR-185.
Insulin activation of rat prolactin promoter activity.
Lnc-SNHG1 Activates the TGFBR2/SMAD3 and RAB11A/Wnt/?-Catenin Pathway by Sponging MiR-302/372/373/520 in Invasive Pituitary Tumors.
LncRNA LINC00473 is involved in the progression of invasive pituitary adenoma by upregulating KMT5A via ceRNA-mediated miR-502-3p evasion.
Molecular mechanisms for somatostatin inhibition of c-fos gene expression.
Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice.
Novel estrogenic action of the pesticide residue beta-hexachlorocyclohexane in human breast cancer cells.
Stimulatory effect of interleukin-1beta on growth hormone gene expression and growth hormone release from rat GH3 cells.
The regulatory mechanism by which interleukin-6 stimulates GH-gene expression in rat GH3 cells.
Thyrotrope expression and thyroid hormone inhibition map to different regions of the mouse glycoprotein hormone alpha-subunit gene promoter.
[Development of a new method for sequential monitoring of transcriptional activities of growth hormone genes by a secreted bioluminescence reporter]
Plague
'Bioluminescent' reporter phage for the detection of category a bacterial pathogens.
Bioluminescent tracking of colonization and clearance dynamics of plasmid-deficient Yersinia pestis strains in a mouse model of septicemic plague.
Diagnostic bioluminescent phage for the detection of Yersinia pestis.
Real-Time Monitoring of Yersinia pestis Promoter Activity by Bioluminescence Imaging.
Plasmacytoma
An acute phase response factor/NF-kappa B site downstream of the junB gene that mediates responsiveness to interleukin-6 in a murine plasmacytoma.
Curcumin nicotinate suppresses abdominal aortic aneurysm pyroptosis via lncRNA PVT1/miR-26a/KLF4 axis through regulating the PI3K/AKT signaling pathway.
Inducible nuclear factors binding the IgM heavy chain pre-mRNA secretory poly(A) site.
PVT1 (rs13281615) and miR-146a (rs2910164) polymorphisms affect the prognosis of colon cancer by regulating COX2 expression and cell apoptosis.
The murine Ig 3' alpha enhancer is a target site with repressor function for the B cell lineage-specific transcription factor BSAP (NF-HB, S alpha-BP).
The transcription factor MZF1 differentially regulates murine Mtor promoter variants linked to tumor susceptibility.
Pneumonia
An IL-8 Transiently Transgenized Mouse Model for the In Vivo Long-term Monitoring of Inflammatory Responses.
CHF6001 Inhibits NF-?B Activation and Neutrophilic Recruitment in LPS-Induced Lung Inflammation in Mice.
High-dose dexamethasone accentuates nuclear factor-kappa b activation in endotoxin-treated mice.
In vivo monitoring of lung inflammation in CFTR-deficient mice.
Kefir peptides alleviate particulate matter <4 ?m (PM4.0)-induced pulmonary inflammation by inhibiting the NF-?B pathway using luciferase transgenic mice.
Lung-specific expression of adenovirus E3-14.7K in transgenic mice attenuates adenoviral vector-mediated lung inflammation and enhances transgene expression.
MicroRNAs are dynamically regulated and play an important role in LPS-induced lung injury.
Persistence of replication-deficient adenovirus-mediated gene transfer in lungs of immune-deficient (nu/nu) mice.
Pneumonia, Ventilator-Associated
One functional variant in the 3'-untranslated region of TLR4 is associated with the elevated risk of ventilator-associated pneumonia in the patients with chronic obstructive pulmonary disease.
Polycystic Kidney Diseases
MicroRNA-106b-5p regulates cisplatin chemosensitivity by targeting polycystic kidney disease-2 in non-small-cell lung cancer.
MiR-4787-5p regulates vascular smooth muscle cell apoptosis by targeting PKD1 and inhibiting the PI3K/Akt/FKHR pathway.
Polycystic Kidney, Autosomal Dominant
Effects of pyrrolidine dithiocarbamate on proliferation and nuclear factor-?B activity in autosomal dominant polycystic kidney disease cells.
Polycystin-1 regulates amphiregulin expression through CREB and AP1 signalling: implications in ADPKD cell proliferation.
Polyendocrinopathies, Autoimmune
IL-6-specific autoantibodies among APECED and thymoma patients.
Porcine Reproductive and Respiratory Syndrome
Development of luciferase-linked antibody capture assay based on luciferase immunoprecipitation systems for antibody detection of porcine reproductive and respiratory syndrome virus.
Electroporation of a nanoparticle-associated DNA vaccine induces higher inflammation and immunity compared to its delivery with microneedle patches in pigs.
Recombinant porcine reproductive and respiratory syndrome virus expressing luciferase genes provide a new indication of viral propagation in both permissive and target cells.
Poxviridae Infections
In Vitro Transcribed RNA-based Luciferase Reporter Assay to Study Translation Regulation in Poxvirus-infected Cells.
Pre-Eclampsia
Stimulating autoantibodies against the angiotensin II type 1 receptor are not associated with preeclampsia in Mexican-Mestizo women.
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Chronic stress enhances progression of acute lymphoblastic leukemia via ?-adrenergic signaling.
MiR-320a inhibits malignant phenotype of melanoma cells via targeting PBX3.
Pre-B-cell leukemia transcription factor 1 regulates expression of valosin-containing protein, a gene involved in cancer growth.
The role of miR-320a and IL-1? in human chondrocyte degradation.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Identification and characterization of the IKKalpha promoter: positive and negative regulation by ETS-1 and p53, respectively.
MiR-7 Functions as a Tumor Suppressor by Targeting the Oncogenes TAL1 in T-Cell Acute Lymphoblastic Leukemia.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Hyper-activation of WNT/?-catenin signaling pathway mediates anti-tumor effects of histone deacetylase inhibitors in acute T lymphoblastic leukemia.
LncRNA ANRIL/miR-7-5p/TCF4 axis contributes to the progression of T cell acute lymphoblastic leukemia.
MicroRNA-204 inhibits cell proliferation in T-cell acute lymphoblastic leukemia by down-regulating SOX4.
miR-664 negatively regulates PLP2 and promotes cell proliferation and invasion in T-cell acute lymphoblastic leukaemia.
Prion Diseases
Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice.
Prolactinoma
MiR-1299 promotes the synthesis and secretion of prolactin by inhibiting FOXO1 expression in drug-resistant prolactinomas.
Prostatic Neoplasms
3,3'-Diindolylmethane Enhances Taxotere-Induced Apoptosis in Hormone-Refractory Prostate Cancer Cells through Survivin Down-regulation.
A functional screen identifies miRNAs that inhibit DNA repair and sensitize prostate cancer cells to ionizing radiation.
A human- and male-specific protocadherin that acts through the wnt signaling pathway to induce neuroendocrine transdifferentiation of prostate cancer cells.
A new luciferase reporter gene assay for the detection of androgenic and antiandrogenic effects based on a human prostate specific antigen promoter and PC3/AR human prostate cancer cells.
A novel androgen receptor antagonist JJ-450 inhibits enzalutamide-resistant mutant ARF876L nuclear import and function.
A TRAMP-derived orthotopic prostate syngeneic (TOPS) cancer model for investigating anti-tumor treatments.
Abrogation of prostaglandin E-EP4 signaling in osteoblasts prevents the bone destruction induced by human prostate cancer metastases.
Adenovirus mediated prostate specific enzyme prodrug gene therapy using prostate specific antigen promoter enhanced by the Cre-loxP system.
Androgen receptor is causally involved in the homeostasis of the human prostate endothelial cell.
Androgen Receptor Regulation of the Versican Gene through an Androgen Response Element in the Proximal Promoter.
Anti-Androgenic Activity of Icarisid II from Epimedium Herb in Prostate Cancer LNCaP Cells.
Anti-Androgenic Activity of Resveratrol Analogs in Prostate Cancer LNCaP Cells.
Anti-prostate cancer activity of 8-hydroxyquinoline-2-carboxaldehyde-thiosemicarbazide copper complexes in vivo by bioluminescence imaging.
Association between genetic polymorphisms in the prostate-specific antigen gene promoter and serum prostate-specific antigen levels.
Bioluminescent imaging study: FAK inhibitor, PF-562,271, preclinical study in PC3M-luc-C6 local implant and metastasis xenograft models.
Characterization of two functional NKX3.1 binding sites upstream of the PCAN1 gene that are involved in the positive regulation of PCAN1 gene transcription.
Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells.
Combined cryoablation and GM-CSF treatment for metastatic hormone refractory prostate cancer.
Combining Optical Reporter Proteins with Different Half-lives to Detect Temporal Evolution of Hypoxia and Reoxygenation in Tumors.
Conjugation with Receptor-Targeted Histidine-Rich Peptides Enhances the Pharmacological Effectiveness of Antisense Oligonucleotides.
Constraints to counting bioluminescence producing cells by a commonly used transgene promoter and its implications for experimental design.
Construction of strong mammalian promoters by random cis-acting element elongation.
Drugs which inhibit osteoclast function suppress tumor growth through calcium reduction in bone.
Effects of lactone derivatives on aromatase (CYP19) activity in H295R human adrenocortical and (anti)androgenicity in transfected LNCaP human prostate cancer cells.
Effects of microRNA-221/222 on cell proliferation and apoptosis in prostate cancer cells.
Efficient transfection of tumors facilitated by long-term therapeutic ultrasound in combination with contrast agent: from in vitro to in vivo setting.
Enhancement of androgen-dependent transcription and cell proliferation by tributyltin and triphenyltin in human prostate cancer cells.
Enhancement of PSMA-Directed CAR Adoptive Immunotherapy by PD-1/PD-L1 Blockade.
Evaluation of 19-nor-2alpha-(3-hydroxypropyl)-1alpha,25-dihydroxyvitamin D3 as a therapeutic agent for androgen-dependent prostate cancer.
Exosome circ_0044516 promotes prostate cancer cell proliferation and metastasis as a potential biomarker.
Exploiting the transcriptional specificity of the alpha-methylacyl-CoA racemase AMACR promoter for the molecular imaging of prostate cancer.
EZC-prostate models offer high sensitivity and specificity for noninvasive imaging of prostate cancer progression and androgen receptor action.
Frequently rearranged in advanced T?cell lymphomas?1 demonstrates oncogenic properties in prostate cancer.
Functional domains of androgen receptor coactivator p44/Mep50/WDR77and its interaction with Smad1.
Genistein downregulates onco-miR-1260b and upregulates sFRP1 and Smad4 via demethylation and histone modification in prostate cancer cells.
Grape seed extract regulates androgen receptor-mediated transcription in prostate cancer cells through potent anti-histone acetyltransferase activity.
Hypoxia theranostics of a human prostate cancer xenograft and the resulting effects on the tumor microenvironment.
Id-1 expression induces androgen-independent prostate cancer cell growth through activation of epidermal growth factor receptor (EGF-R).
Identification and characterization of the novel human prostate cancer-specific PC-1 gene promoter.
Identification of an additional hypoxia responsive element in the glyceraldehyde-3-phosphate dehydrogenase gene promoter.
Immunologic response to primary cryoablation of high-risk prostate cancer.
Impact of prostate inflammation on lesion development in the POET3(+)Pten(+/-) mouse model of prostate carcinogenesis.
In vivo and in vitro effects of a HIF-1alpha inhibitor, RX-0047.
In vivo evaluation of a novel albumin-binding prodrug of doxorubicin in an orthotopic mouse model of prostate cancer (LNCaP).
In vivo regulation of hTERT expression and telomerase activity by androgen.
In vivo suicide gene therapy model using a newly discovered prostate-specific membrane antigen promoter/enhancer: a potential alternative approach to androgen deprivation therapy.
Inhibition of cancer cell-derived exosomal microRNA-183 suppresses cell growth and metastasis in prostate cancer by upregulating TPM1.
Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with {beta}-phenylethyl isothiocyanate and curcumin.
Inhibition of microRNA-500 has anti-cancer effect through its conditional downstream target of TFPI in human prostate cancer.
Inhibition of prostate cancer neovascularization and growth by urokinase-plasminogen activator receptor blockade.
Inhibition of Protein Kinase CK2 Reduces Cyp24a1 Expression and Enhances 1,25-Dihydroxyvitamin D3 Antitumor Activity in Human Prostate Cancer Cells.
Insulin-like growth factor 1 stimulation of androgen receptor activity requires ?(1A) integrins.
Interleukin-17 promotes metastasis in an immunocompetent orthotopic mouse model of prostate cancer.
Ku is a novel transcriptional recycling coactivator of the androgen receptor in prostate cancer cells.
KU675, a Concomitant Heat-Shock Protein Inhibitor of Hsp90 and Hsc70 that Manifests Isoform Selectivity for Hsp90? in Prostate Cancer Cells.
Limited specificity of promoter constructs for gene therapy in osteosarcoma.
LncRNA BLACAT1 Promotes Proliferation, Migration and Invasion of Prostate Cancer Cells via Regulating miR-29a-3p/DVL3 Axis.
Locally invasive, castrate-resistant prostate cancer in a Pten/Trp53 double knockout mouse model of prostate cancer monitored with non-invasive bioluminescent imaging.
Long non-coding RNA BLACAT1 inhibits prostate cancer cell proliferation through sponging miR-361.
LSD1 inhibition attenuates androgen receptor V7 splice variant activation in castration resistant prostate cancer models.
MEF2?activated long non?coding RNA PCGEM1 promotes cell proliferation in hormone?refractory prostate cancer through downregulation of miR?148a.
Metastasizing, Luciferase Transduced MAT?Lu Rat Prostate Cancer Models: Follow up of Bolus and Metronomic Therapy with Doxorubicin as Model Drug.
MicroRNA-143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer.
microRNA-155 promotes the proliferation of prostate cancer cells by targeting annexin 7.
MicroRNA-200a suppresses prostate cancer progression through BRD4/AR signaling pathway.
MicroRNA-455-3p functions as a tumor suppressor by targeting eIF4E in prostate cancer.
MicroRNA-497 targets hepatoma-derived growth factor and suppresses human prostate cancer cell motility.
MicroRNA?198 suppresses prostate tumorigenesis by targeting MIB1.
microRNA?99a inhibits cell proliferation, colony formation ability, migration and invasion by targeting fibroblast growth factor receptor 3 in prostate cancer.
MiR-150 promotes the cell invasion of prostate cancer cells by directly regulating the expression of p53.
miR-17* suppresses tumorigenicity of prostate cancer by inhibiting mitochondrial antioxidant enzymes.
miR-24-3p stimulates migration, invasion and proliferation of prostate cancer cells by targeting suppressor of cytokine signaling 6.
MiR-26a inhibits prostate cancer progression by repression of Wnt5a.
MiR-373 Inhibits the Epithelial-Mesenchymal Transition of Prostatic Cancer via Targeting Runt-Related Transcription Factor 2.
miR-483-5p promotes prostate cancer cell proliferation and invasion by targeting RBM5.
MiRNA regulation of TRAIL expression exerts selective cytotoxicity to prostate carcinoma cells.
Mitogen-activated protein kinase pathway is involved in alpha6 integrin gene expression in androgen-independent prostate cancer cells: role of proximal Sp1 consensus sequence.
MNS16A tandem repeat minisatellite of human telomerase gene: functional studies in colorectal, lung and prostate cancer.
Modulation of activator protein-1 (AP-1) and MAPK pathway by flavonoids in human prostate cancer PC3 cells.
Monitoring luciferase-labeled human prostate stem cell antigen-expressing tumor growth in a mouse model.
Monitoring of prostate cancer growth and metastasis using a PSA luciferase report plasmid in a mouse model.
Non-invasive imaging of engineered human tumors in the living chicken embryo.
Non-invasive imaging of firefly luciferase reporter gene expression using bioluminescence imaging in human prostate cancer models.
Novel binding of HuR and poly(C)-binding protein to a conserved UC-rich motif within the 3'-untranslated region of the androgen receptor messenger RNA.
Novel prostate-specific promoter derived from PSA and PSMA enhancers.
Oncostatin M promotes mesenchymal stem cell-stimulated tumor growth through a paracrine mechanism involving periostin and TGFBI.
Overexpression of the zinc uptake transporter hZIP1 inhibits nuclear factor-kappaB and reduces the malignant potential of prostate cancer cells in vitro and in vivo.
PC-SPES: Molecular mechanism to induce apoptosis and down-regulate expression of PSA in LNCaP human prostate cancer cells.
Piceatannol inhibits migration and invasion of prostate cancer cells: possible mediation by decreased interleukin-6 signaling.
Real-time monitoring of tumor progression and drug responses in a preclinical mouse model of prostate cancer.
Reduced expression of the androgen receptor by third generation of antisense shows antitumor activity in models of prostate cancer.
Reduction of metastasis using a non-volatile buffer.
Regulation of prostate cancer cell growth and PSA expression by angiotensin II receptor blocker with peroxisome proliferator-activated receptor gamma ligand like action.
Regulation of steroid hydroxylase CYP7B1 by androgens and estrogens in prostate cancer LNCaP cells.
Repression of MicroRNA-372 by Arsenic Sulphide Inhibits Prostate Cancer Cell Proliferation and Migration through Regulation of large tumour suppressor kinase 2.
Single-nucleotide polymorphism rs13426236 contributes to an increased prostate cancer risk via regulating MLPH splicing variant 4.
Slow disease progression in a C57BL/6 pten-deficient mouse model of prostate cancer.
Small Molecule Antagonists of the Nuclear Androgen Receptor for the Treatment of Castration-Resistant Prostate Cancer.
Sp1 and Sp3 transcription factors upregulate the proximal promoter of the human prostate-specific antigen gene in prostate cancer cells.
Splicing Factor Prp8 Interacts With NES(AR) and Regulates Androgen Receptor in Prostate Cancer Cells.
STAT3 mediates IL-6-induced growth inhibition in the human prostate cancer cell line LNCaP.
Structural and functional analysis of amino-terminal enhancer of split in androgen-receptor-driven transcription.
Suppression of hormone-refractory prostate cancer by a novel nuclear factor kappaB inhibitor in nude mice.
Synthesis and biological evaluation of an albumin-binding prodrug of doxorubicin that is cleaved by prostate-specific antigen (PSA) in a PSA-positive orthotopic prostate carcinoma model (LNCaP).
Targeted therapy with fatty acid synthase inhibitors in a human prostate carcinoma LNCaP/tk-luc-bearing animal model.
Targeting of prostate cancer cells by a cytotoxic lentiviral vector containing a prostate stem cell antigen (PSCA) promoter.
TGF-beta signaling and androgen receptor status determine apoptotic cross-talk in human prostate cancer cells.
The atypical GATA protein TRPS1 represses androgen-induced prostate-specific antigen expression in LNCaP prostate cancer cells.
The modified firefly luciferase reporter gene (luc+) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells.
The transcription factor SPDEF is required for E-Cadherin expression in prostate cancer cells.
Transcriptional activation of the human gastrin-releasing peptide receptor gene in gastrointestinal and prostatic epithelial cancer cells.
Transcriptional regulation of the homeobox gene NKX3.1 by all-trans retinoic acid in prostate cancer cells.
Transcriptional regulation of the major zinc uptake protein hZip1 in prostate cancer cells.
Transforming growth factor-? signaling induced during prostate cancer cell death and neuroendocrine differentiation is mediated by bone marrow stromal cells.
Two-step transcriptional amplification-lipid-based nanoparticles using PSMA or midkine promoter for suicide gene therapy in prostate cancer.
[Identification of response element gene sequence for non-steroid hormone transcription factors for the activation and up-regulation of L-plastin expression in prostate cancer]
[Inhibition of the expression of prostate specific antigen by curcumin]
Prostatitis
Impact of prostate inflammation on lesion development in the POET3(+)Pten(+/-) mouse model of prostate carcinogenesis.
Proteinuria
MicroRNA?199a?3p suppresses high glucose?induced apoptosis and inflammation by regulating the IKK?/NF??B signaling pathway in renal tubular epithelial cells.
Pseudorabies
A NanoLuc Luciferase Reporter Pseudorabies Virus for Live Imaging and Quantification of Viral Infection.
Psoriasis
USP2 as a potential link between miR-125b and psoriasis.
Pulmonary Disease, Chronic Obstructive
MicroRNA-221-3p alleviates cell apoptosis and inflammatory response by targeting cyclin dependent kinase inhibitor 1B in chronic obstructive pulmonary disease.
miR-422a suppresses SMAD4 protein expression and promotes resistance to muscle loss.
miRNA-486-5p Promotes COPD Progression by Targeting HAT1 to Regulate the TLR4-Triggered Inflammatory Response of Alveolar Macrophages.
Pulmonary Fibrosis
Luciferase expression is driven by the promoter of fibroblast activation protein-? in murine pulmonary fibrosis
Luciferase expression is driven by the promoter of fibroblast activation protein-? in murine pulmonary fibrosis.
miR-205 Suppresses Pulmonary Fibrosis By Targeting GATA3 Through Inhibition Of Endoplasmic Reticulum Stress.
The Anti-fibrotic Effects and Mechanisms of MicroRNA-486-5p in Pulmonary Fibrosis.
Rabies
A recombinant rabies virus expressing luciferase.
Generation of recombinant rabies viruses encoding NanoLuc luciferase for antiviral activity assays.
Novel, rapid assay for measuring entry of diverse enveloped viruses, including HIV and rabies.
Peptides that mimic the amino-terminal end of the rabies virus phosphoprotein have antiviral activity.
Protection of bats (Eptesicus fuscus) against rabies following topical or oronasal exposure to a recombinant raccoon poxvirus vaccine.
Rectal Neoplasms
Murine orthotopic model for the assessment of chemoradiotherapeutic interventions in rectal cancer.
SNHG17 Serves as an Oncogenic lncRNA by Regulating the miR-361-3p/STC2 Axis in Rectal Cancer.
Relative Energy Deficiency in Sport
A small nuclear acidic protein (MTI-II, Zn2+-binding protein, parathymosin) attenuates TNF-? inhibition of BMP-induced osteogenesis by enhancing accessibility of the Smad4-NF-?B p65 complex to Smad binding element.
MiR-155-5p regulates mesenchymal stem cell osteogenesis and proliferation via targeting GSK3B in steroid-associated osteonecrosis.
MiR-217 promotes cell proliferation and osteogenic differentiation of BMSCs by targeting DKK1 in steroid-associated osteonecrosis.
Synergistic stimulating effect of 2-hydroxymelatonin and BMP-4 on osteogenic differentiation in vitro.
Reperfusion Injury
Bioluminescence Imaging Visualizes Activation of Nuclear Factor-kappaB in Mouse Cardiac Transplantation.
Inhibition of miR-34a-5p protected myocardial ischemia reperfusion injury-induced apoptosis and reactive oxygen species accumulation through regulation of Notch Receptor 1 signaling.
Retinitis Pigmentosa
Development of a Reporter System to Explore MMEJ in the Context of Replacing Large Genomic Fragments.
Development of photoreceptor-specific promoters and their utility to investigate EIAV lentiviral vector mediated gene transfer to photoreceptors.
Retinoblastoma
A short, highly active photoreceptor-specific enhancer/promoter region upstream of the human rhodopsin kinase gene.
Analysis of the 5' regulatory region of the human Norrie's disease gene: evidence that a non-translated CT dinucleotide repeat in exon one has a role in controlling expression.
Conserved transcriptional regulation of a cone phototransduction gene in vertebrates.
Expression of minichromosome maintenance proteins in vascular smooth muscle cells is ERK/MAPK dependent.
Ginsenoside Rh2-mediated G1 phase cell cycle arrest in human breast cancer cells is caused by p15 Ink4B and p27 Kip1-dependent Inhibition of cyclin-dependent kinases.
HGUE-C-1 is an atypical and novel colon carcinoma cell line.
Identification of an RB-responsive region in the 5' untranslated region of the RB gene.
INSM1 Promoter-Driven Adenoviral Herpes Simplex Virus Thymidine Kinase Cancer Gene Therapy for the Treatment of Primitive Neuroectodermal Tumors.
MicroRNA-101-3p inhibits proliferation in retinoblastoma cells by targeting EZH2 and HDAC9.
MicroRNA-215 promoted the progression of nasopharyngeal carcinoma through targeting RB1 and activating Wnt/?-catenin pathway.
miR-1297 promotes cell proliferation by inhibiting RB1 in liver cancer.
miR-215 promotes cell migration and invasion of gastric cancer by targeting Retinoblastoma tumor suppressor gene 1.
MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network.
Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer.
Regulatory sequences in the 3' Untranslated region of the human cGMP-Phosphodiesterase {beta}-Subunit gene.
Retinoblastoma suppressor associated protein 46 (RbAp46) attenuates the beta-catenin/TCF signaling through up-regulation of GSK-3beta expression.
TGF-{beta} type II Receptor mRNA in Retinoblastoma Cell Lines is induced by Trichostatin A.
The expression of retinoblastoma and Sp1 is increased by low concentrations of cyclin-dependent kinase inhibitors.
Treating retinoblastoma in tissue culture and in a rat model with a novel isoquinoline derivative.
Rhabdomyosarcoma
Development of a Coxsackievirus A16 neutralization assay based on pseudoviruses for measurement of neutralizing antibody titer in human serum.
Development of a stable Gaussia luciferase enterovirus 71 reporter virus.
Expansion of tropism of a feline parvovirus to target a human tumor cell line by display of an alpha(v) integrin binding peptide on the capsid.
Functional characterization of the human PAX3 gene regulatory region.
Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells.
Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element.
Rhabdomyosarcoma, Alveolar
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Rheumatic Diseases
Ganglionic Acetylcholine Receptor Antibodies and Autonomic Dysfunction in Autoimmune Rheumatic Diseases.
Rhinitis, Allergic
miR-487b mitigates allergic rhinitis through inhibition of the IL-33/ST2 signaling pathway.
Rotavirus Infections
Interleukin-8 gene regulation in intestinal epithelial cells infected with rotavirus: role of viral-induced IkappaB kinase activation.
Rubella
The construction of defective interfering rubella virus particles.
The preparation of bacterial luciferase conjugates for immunoassay and application to rubella antibody detection.
Sarcoma
A Trp53fl/flPtenfl/fl mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection and in vivo bioluminescence imaging.
Alternative promoters of gene MAGE4a.
COL11A2 collagen gene transcription is differentially regulated by EWS/ERG sarcoma fusion protein and wild-type ERG.
miR-134 functions as a tumor suppressor in cell proliferation and epithelial-to-mesenchymal Transition by targeting KRAS in renal cell carcinoma cells.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Sarcoma derived from cultured mesenchymal stem cells.
Sarcoma, Avian
A cell line that expresses a reporter gene in response to infection by Sindbis virus: a prototype for detection of positive strand RNA viruses.
Adenovirus-mediated augmentation of cell transfection with unmodified plasmid vectors.
Antitumoral gene-based strategy involving nitric oxide synthase type III overexpression in hepatocellular carcinoma.
Behavior of genes directly injected into the rat heart in vivo.
cAMP regulates G-protein alpha i-2 subunit gene transcription in polarized LLC-PK1 cells by induction of a CCAAT box nuclear binding factor.
Cytoplasmic gene expression system enhances the efficiency of cationic liposome-mediated in vivo gene transfer into mouse brain.
Dexamethasone enhancement of gene expression after direct hepatic DNA injection.
Direct gene transfer into skeletal muscle in vivo: factors affecting efficiency of transfer and stability of expression.
Evaluation of viral and mammalian promoters for driving transgene expression in mouse liver.
Evaluation of viral and mammalian promoters for use in gene delivery to salivary glands.
Functional studies of a germ-line polymorphism at codon 47 within the p53 gene.
Gene delivery and expression in human retinal pigment epithelial cells: effects of synthetic carriers, serum, extracellular matrix and viral promoters.
Genomic structure and functional analysis of promoter region of somatolactin gene of sea bream (Sparus aurata).
High level of transgene expression in cell cultures and in the mouse by replication-incompetent adenoviruses harboring modified VAI genes.
Human ethanol-inducible P450IIE1: complete gene sequence, promoter characterization, chromosome mapping, and cDNA-directed expression.
Identification of mouse histone deacetylase 1 as a growth factor-inducible gene.
Ischemic/reperfused myocardium can express recombinant protein following direct DNA or retroviral injection.
Mechanism of enhancement of DNA expression consequent to cointernalization of a replication-deficient adenovirus and unmodified plasmid DNA.
Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins.
Nitric Oxide Synthase Type III Overexpression By Gene Therapy Exerts Antitumoral Activity In Mouse Hepatocellular Carcinoma.
Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP.
Pharmacological expression in rat hepatocytes of a gene transferred by an adenovirus vector enabled by a chimeric promoter containing multiple cyclic adenosine monophosphate response elements.
Preservation of myocardial function after adenoviral gene transfer in isolated myocardium.
Reporter gene expression in fish following cutaneous infection with pantropic retroviral vectors.
The mouse p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1) gene. Genomic organization and structure of the 5'-flanking regulatory region.
Transcriptional activation of the ovine follicle-stimulating hormone beta-subunit gene by gonadotropin-releasing hormone: involvement of two activating protein-1-binding sites and protein kinase C.
Transgene expression in the brain stem effected by intramuscular injection of polyethylenimine/DNA complexes.
Up to 100-fold increase of apparent gene expression in the presence of Epstein-Barr virus oriP sequences and EBNA1: implications of the nuclear import of plasmids.
Up-regulation of CRKL by microRNA-335 methylation is associated with poor prognosis in gastric cancer.
Sarcoma, Ewing
Analysis of Regulatory DNA Sequences by Dual-Luciferase Reporter Assays in Ewing Sarcoma.
Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor.
Use of transcription reporters with novel p53 binding sites to target tumour cells expressing endogenous or virally transduced p53 mutants with altered sequence-specificity.
Sarcoma, Kaposi
Four-antigen mixture containing v-cyclin for serological screening of human herpesvirus 8 infection.
The Cancer-Associated Virus Landscape in HIV Patients with Oral Hairy Leukoplakia, Kaposi's Sarcoma, and Non-Hodgkin Lymphoma.
Sepsis
An inducible nitric oxide synthase-luciferase reporter system for in vivo testing of anti-inflammatory compounds in transgenic mice.
Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in transgenic mice.
Functional imaging of rel expression in inflammatory processes using bioluminescence imaging system in transgenic mice.
Imaging cyclooxygenase-2 (Cox-2) gene expression in living animals with a luciferase knock-in reporter gene.
Inhibition of MicroRNA-23b Attenuates Immunosuppression in Late Sepsis through NIK, TRAF1 and XIAP.
microRNA-103a-3p confers protection against lipopolysaccharide-induced sepsis and consequent multiple organ dysfunction syndrome by targeting HMGB1.
microRNA-98 protects sepsis mice from cardiac dysfunction, liver and lung injury by negatively regulating HMGA2 through inhibiting NF-?B signaling pathway.
MiR-210-3p Enhances Cardiomyocyte Apoptosis and Mitochondrial Dysfunction by Targeting the NDUFA4 Gene in Sepsis-Induced Myocardial Dysfunction.
miR-23b Negatively Regulates Sepsis-Induced Inflammatory Responses by Targeting ADAM10 in Human THP-1 Monocytes.
Rapid induction of autoantibodies during ARDS and septic shock.
Simian virus 40 vectors for pulmonary gene therapy.
Tracing the dynamic expression of the Nf?b2 gene during inflammatory processes by in vivo bioluminescence imaging in transgenic mice.
Septo-Optic Dysplasia
Novel application of luciferase assay for the in vitro functional assessment of KAL1 variants in three females with septo-optic dysplasia (SOD).
Severe Acute Respiratory Syndrome
SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.
Severe Combined Immunodeficiency
Immune-mediated destruction of transfected muscle fibers after direct gene transfer with antigen-expressing plasmid DNA.
Utility of 211At-trastuzumab for the Treatment of Metastatic Gastric Cancer in the Liver: Evaluation of a Preclinical ?-Radioimmunotherapy Approach in a Clinically-relevant Mouse Model.
Silicosis
Functional variant of the carboxypeptidase M (CPM) gene may affect silica-related pneumoconiosis susceptibility by its expression: a multistage case-control study.
Skin Neoplasms
Down-Regulation of miR-148a Promotes Metastasis by DNA Methylation and is Associated with Prognosis of Skin Cancer by Targeting TGIF2.
Hyaluronate-Gold Nanorod/DR5 Antibody Complex for Noninvasive Theranosis of Skin Cancer.
UVA and UVB irradiation differentially regulate microRNA expression in human primary keratinocytes.
Small Cell Lung Carcinoma
Characterization of a functional promoter polymorphism of the human tryptophan hydroxylase 2 gene in serotonergic raphe neurons.
miR-181b inhibits chemoresistance in cisplatin-resistant H446 small cell lung cancer cells by targeting Bcl-2.
The anti-infection drug furazolidone inhibits NF-?B signaling and induces cell apoptosis in small cell lung cancer.
The Expression of miR-375 Is Associated with Carcinogenesis in Three Subtypes of Lung Cancer.
Spinal Cord Injuries
RXR? Blocks Nerve Regeneration after Spinal Cord Injury by Targeting p66shc.
Swim training initiated acutely after spinal cord injury is ineffective and induces extravasation in and around the epicenter.
Squamous Cell Carcinoma of Head and Neck
Cepharanthin-enhanced radiosensitivity through the inhibition of radiation-induced nuclear factor-kappaB activity in human oral squamous cell carcinoma cells.
HPV E6 and E7 Mediated Regulation of HPV(-) HNSCC Cell Lines.
LINC00958-MYC positive feedback loop modulates resistance of head and neck squamous cell carcinoma cells to chemo- and radiotherapy in vitro.
Long noncoding RNA MEG3 decreases the growth of head and neck squamous cell carcinoma by regulating the expression of miR-421 and E-cadherin.
Luciferase-Based Detection of Antibodies for the Diagnosis of HPV-Associated Head and Neck Squamous Cell Carcinoma.
MicroRNA-200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells.
MiR-501-5p acts as an energetic regulator in head and neck squamous cell carcinoma cells growth and aggressiveness via reducing CLCA4.
Physiologic and molecular characterization of a novel murine model of metastatic head and neck cancer cachexia.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Reciprocal transactivation of Merkel cell polyomavirus and high-risk human papillomavirus promoter activities and increased expression of their oncoproteins.
TGF-?-induced STAT3 overexpression promotes human head and neck squamous cell carcinoma invasion and metastasis through malat1/miR-30a interactions.
The role of HOXB9 and miR-196a in head and neck squamous cell carcinoma.
Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly suppressed metastasis-promoting LOXL2 in head and neck squamous cell carcinoma.
Upregulated miR?20a?5p expression promotes proliferation and invasion of head and neck squamous cell carcinoma cells by targeting of TNFRSF21.
Wnt/Beta-Catenin Signal Inhibitor HC-1 Sensitizes Oral Squamous Cell Carcinoma Cells to 5-Fluorouracil through Reduction of CD44-Positive Population.
[Inflammatory factors promote oral squamous cell carcinoma cells metastasis, via nuclear factor kappa B signal pathway in vitro]
Staphylococcal Infections
A stable luciferase reporter plasmid for in vivo imaging in murine models of Staphylococcus aureus infections.
Starvation
A Transcriptome Meta-Analysis Proposes Novel Biological Roles for the Antifungal Protein AnAFP in Aspergillus niger.
Activation of the promoters of Arabidopsis genes for the branched-chain alpha-keto acid dehydrogenase complex in transgenic tobacco BY-2 cells under sugar starvation.
Assay of ATP in intact cells of the facultative phototroph Rhodobacter capsulatus expressing recombinant firefly luciferase.
Bioluminescent Escherichia coli strains for the quantitative detection of phosphate and ammonia in coastal and suburban watersheds.
Branched-Chain Amino Acid Negatively Regulates KLF15 Expression via PI3K-AKT Pathway.
Cell cycle-dependent regulation of the bi-directional overlapping promoter of human BRCA2/ZAR2 genes in breast cancer cells.
Characterization and cell cycle regulation of the major Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) latent genes and their promoter.
Codon optimality controls differential mRNA translation during amino acid starvation.
Differential expression of speckled POZ protein, SPOP: putative regulation by miR-145.
Glucose Regulates Foxo1 Through Insulin Receptor Signaling in the Pancreatic Islet {beta}-cell.
Metabolic reprogramming during purine stress in the protozoan pathogen Leishmania donovani.
Nitrate-inducible NIGT1 proteins modulate phosphate uptake and starvation signalling via transcriptional regulation of SPX genes.
Post-transcriptional regulation of ribosomal protein genes during serum starvation in Entamoeba histolytica.
Simultaneous monitoring of cell number and metabolic activity of specific bacterial populations with a dual gfp-luxAB marker system.
Status Epilepticus
Antagonist Targeting microRNA-155 Protects against Lithium-Pilocarpine-Induced Status Epilepticus in C57BL/6 Mice by Activating Brain-Derived Neurotrophic Factor.
Stiff-Person Syndrome
High definition profiling of autoantibodies to glutamic acid decarboxylases GAD65/GAD67 in stiff-person syndrome.
Stomach Neoplasms
A miR-570 binding site polymorphism in the B7-H1 gene is associated with the risk of gastric adenocarcinoma.
Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1.
An orthotopic mouse model of gastric cancer invasion and metastasis.
Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan.
Bufalin promotes apoptosis of gastric cancer by down-regulation of miR-298 targeting bax.
Control of expression of the lectin-like protein Reg-1 by gastrin: role of the Rho family GTPase RhoA and a C-rich promoter element.
CST1 Promoted Gastric Cancer Migration and Invasion Through Activating Wnt Pathway.
Decrease of 5hmC in gastric cancers is associated with TET1 silencing due to with DNA methylation and bivalent histone marks at TET1 CpG island 3'-shore.
DNMT3A-mediated down-regulation of microRNA-105 promotes gastric cancer cell proliferation.
Down-Regulation of circNRIP1 Promotes the Apoptosis and Inhibits the Migration and Invasion of Gastric Cancer Cells by miR-182/ROCK1 Axis.
Effects of Combined Simultaneous and Sequential Endostar and Cisplatin Treatment in a Mice Model of Gastric Cancer Peritoneal Metastases.
Heat-directed suicide gene therapy mediated by heat shock protein promoter for gastric cancer.
Helicobacter pylori induced transactivation of SRE and AP-1 through the ERK signalling pathway in gastric cancer cells.
Human gastrin mRNA expression up-regulated by Helicobacter pylori CagA through MEK/ERK and JAK2-signaling pathways in gastric cancer cells.
Hypoxia Induced Overexpression of PrP(C) in Gastric Cancer Cell Lines.
I?B? polymorphisms were associated with increased risk of gastric cancer in a southern Chinese population: A case-control study.
Identification and characterization of the retinoic acid response elements in the human RIG1 gene promoter.
Identification of miR-30e* regulation of Bmi1 expression mediated by tumor-associated macrophages in gastrointestinal cancer.
IGFBP3, a transcriptional target of homeobox D10, is correlated with the prognosis of gastric cancer.
Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis.
Inhibition of microRNA-17/20a suppresses cell proliferation in gastric cancer by modulating UBE2C expression.
Integrated MicroRNA-mRNA Analysis Reveals miR-204 Inhibits Cell Proliferation in Gastric Cancer by Targeting CKS1B, CXCL1 and GPRC5A.
Itraconazole induces apoptosis and cell cycle arrest via inhibiting Hedgehog signaling in gastric cancer cells.
KIAA1429 regulates cell proliferation by targeting c-Jun messenger RNA directly in gastric cancer.
LINC00511 promotes proliferation and invasion by sponging miR-515-5p in gastric cancer.
Long non-coding RNA FTX promotes gastric cancer progression by targeting miR-215.
Long noncoding RNA LINC00982 upregulates CTSF expression to inhibit gastric cancer progression via the transcription factor HEY1.
Long noncoding RNA SNHG16 silencing inhibits the aggressiveness of gastric cancer via upregulation of microRNA-628-3p and consequent decrease of NRP1.
MicroRNA-125b promotes invasion and metastasis of gastric cancer by targeting STARD13 and NEU1.
MicroRNA-139 inhibits the proliferation, migration and invasion of gastric cancer cells by directly targeting ?-associated protein kinase 1.
MicroRNA-141 inhibits migration of gastric cancer by targeting zinc finger E-box-binding homeobox 2.
microRNA-155 is downregulated in gastric cancer cells and involved in cell metastasis.
MicroRNA-183 inhibits gastric cancer proliferation and invasion via directly targeting Bmi-1.
microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN.
MicroRNA-222-3p associated with Helicobacter pylori targets HIPK2 to promote cell proliferation, invasion, and inhibits apoptosis in gastric cancer.
MicroRNA-28 promotes cell proliferation and invasion in gastric cancer via the PTEN/PI3K/AKT signalling pathway.
MicroRNA-29a inhibits cell migration and invasion via targeting Roundabout homolog 1 in gastric cancer cells.
MicroRNA-340 promotes the tumor growth of human gastric cancer by inhibiting cyclin G2.
MicroRNA-375 reverses the expression of PD-L1 by inactivating the JAK2/STAT3 signaling pathways in gastric cancer.
MicroRNA-381 inhibits the metastasis of gastric cancer by targeting TMEM16A expression.
MicroRNA-449a inhibits proliferation and induces apoptosis by directly repressing E2F3 in gastric cancer.
MicroRNA-577 inhibits gastric cancer growth by targeting E2F transcription factor 3.
MicroRNA?499 rs3746444 A/G polymorphism functions as a biomarker to predict recurrence following endoscopic submucosal dissection in primary early gastric cancer.
MicroRNA?744 inhibits tumor cell proliferation and invasion of gastric cancer via targeting brain?derived neurotrophic factor.
miR 1296-5p Inhibits the Migration and Invasion of Gastric Cancer Cells by Repressing ERBB2 Expression.
MiR-105 inhibits gastric cancer cells metastasis, epithelial-mesenchymal transition by targeting SOX9.
miR-107 targets cyclin-dependent kinase 6 expression, induces cell cycle G1 arrest and inhibits invasion in gastric cancer cells.
miR-129-5p attenuates cell proliferation and epithelial mesenchymal transition via HMGB1 in gastric cancer.
miR-130a acts as a potential diagnostic biomarker and promotes gastric cancer migration, invasion and proliferation by targeting RUNX3.
MiR-216b inhibits gastric cancer proliferation and migration by targeting PARK7.
miR-218 inhibits proliferation, migration, and EMT of gastric cancer cells by targeting WASF3.
MiR-320a inhibits gastric carcinoma by targeting activity in the FoxM1-P27KIP1 axis.
MiR-338-3p inhibits the proliferation and migration of gastric cancer cells by targeting ADAM17.
miR-374a-5p: A New Target for Diagnosis and Drug Resistance Therapy in Gastric Cancer.
MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2.
MiR-450a-5p Inhibits Gastric Cancer Cell Proliferation, Migration, and Invasion and Promotes Apoptosis via Targeting CREB1 and Inhibiting AKT/GSK-3? Signaling Pathway.
miR-494 Sensitizes Gastric Cancer Cells to TRAIL Treatment Through Downregulation of Survivin.
miRNA-223 inhibits epithelial-mesenchymal transition in gastric carcinoma cells via Sp1.
Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer.
p38MAPK Signaling Enhances Glycolysis Through the Up-Regulation of the Glucose Transporter GLUT-4 in Gastric Cancer Cells.
Peritoneal Metastatic Cancer Stem Cells of Gastric Cancer with Partial Mesenchymal-Epithelial Transition and Enhanced Invasiveness in an Intraperitoneal Transplantation Model.
Profiling of Virus-encoded MicroRNAs in Epstein-Barr Virus-associated Gastric Carcinoma and their Roles in Gastric Carcinogenesis.
Real-time bioluminescence and tomographic imaging of gastric cancer in a novel orthotopic mouse model.
REG Ialpha protein may function as a trophic and/or anti-apoptotic factor in the development of gastric cancer.
SALL4 activates TGF-?/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis.
SET7/9 promotes H3K4me3 at lncRNA DRAIC promoter to modulate growth and metastasis of glioma.
Short hairpin RNA targeting beta-catenin suppresses cell proliferation and induces apoptosis in human gastric carcinoma cells.
sMicroRNA-1290 inhibits cells proliferation and migration by targeting FOXA1 in gastric cancer cells.
SOX10-dependent CMTM7 expression inhibits cell proliferation and tumor growth in gastric carcinoma.
SP1 reduces autophagic flux through activating p62 in gastric cancer cells.
STAT5A reprograms fatty acid metabolism and promotes tumorigenesis of gastric cancer cells.
Suppression of gastric cancer growth by adenovirus-mediated transfer of the PTEN gene.
Synthetic Circular RNA Functions as a miR-21 Sponge to Suppress Gastric Carcinoma Cell Proliferation.
The LINC00365/SCGB2A1 (Mammaglobin B) Axis Down-Regulates NF-?B Signaling and Is Associated with the Progression of Gastric Cancer.
The lncRNA ZEB2-AS1 is upregulated in gastric cancer and affects cell proliferation and invasion via miR-143-5p/HIF-1? axis.
Transcription factor KLF4 modulates microRNA-106a that targets Smad7 in gastric cancer.
Transcriptional regulation of the human ABO histo-blood group genes is dependent on the N box upstream of the proximal promoter.
TRIM29 functions as an oncogene in gastric cancer and is regulated by miR-185.
Tumor suppressive microRNA-708 targets Notch1 to suppress cell proliferation and invasion in gastric cancer.
[MiR-126 inhibits the proliferation and invasion of gastric cancer by downregulation of IGF-1R].
[The overexpression and significance of MKP-1 in oxygen-deprived gastric cancer cell line SGC7901]
Stroke
Alteration of microRNA 340-5p and Arginase-1 Expression in Peripheral Blood Cells during Acute Ischemic Stroke.
Enriched housing down-regulates the Toll-like receptor 2 response in the mouse brain after experimental stroke.
Future contrast agents for molecular imaging in stroke.
MicroRNA-195 protection against focal cerebral ischemia by targeting CX3CR1.
Neurogenesis upregulation on the healthy hemisphere after stroke enhances compensation for age-dependent decrease of basal neurogenesis.
Strongyloidiasis
Development of Ss-NIE-1 recombinant antigen based assays for immunodiagnosis of strongyloidiasis.
Subacute Sclerosing Panencephalitis
Functional MxA promoter polymorphism associated with subacute sclerosing panencephalitis.
Superinfection
Distinct modes of human immunodeficiency virus type 1 proviral latency revealed by superinfection of nonproductively infected cell lines with recombinant luciferase-encoding viruses.
Non-structural Proteins of Severe Fever With Thrombocytopenia Syndrome Virus Suppress RNA Synthesis in a Transcriptionally Active cDNA-Derived Viral RNA Synthesis System.
Telangiectasis
Resveratrol transcriptionally regulates miRNA-18a-5p expression ameliorating diabetic nephropathy via increasing autophagy.
Teratocarcinoma
MicroRNA-9 and microRNA-326 regulate human dopamine D2 receptor expression and the microRNA-mediated expression regulation is altered by a genetic variant.
Promoter analysis of human corticotropin-releasing factor (CRF) type 1 receptor and regulation by CRF and urocortin.
The IDDM-associated solitary retroviral promoters DQ-LTR3 and DQ-LTR13 have a distinct impact on the expression of selected DQB1 genes in different cell lines in vitro.
The long terminal repeats of the HERV-H human endogenous retrovirus contain binding sites for transcriptional regulation by the Myb protein.
Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.
Teratoma
Minimum CAG repeat in the human calmodulin-1 gene 5' untranslated region is required for full expression.
Preventing Pluripotent Cell Teratoma in Regenerative Medicine Applied to Hematology Disorders.
Theranostic effect of serial manganese-enhanced magnetic resonance imaging of human embryonic stem cell derived teratoma.
Thrombosis
Ceramidase critically affects GPVI-dependent platelet activation and thrombus formation.
Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels.
Thymoquinone Modulates Blood Coagulation in Vitro via Its Effects on Inflammatory and Coagulation Pathways.
Thymoma
Development of an in vitro test system measuring transcriptional downregulatory activities on IL-13.
Establishment of an in vitro test system to evaluate the down-regulatory activities of natural products on IL-4.
IL-6-specific autoantibodies among APECED and thymoma patients.
The regulation of CD5 expression in murine T cells.
Thyroid Cancer, Papillary
A GC box in the human sodium iodide symporter gene promoter is essential for full activity.
Transcriptional activation of the thyroglobulin promoter directing suicide gene expression by thyroid transcription factor-1 in thyroid cancer cells.
Thyroid Carcinoma, Anaplastic
Adenovirus HSV-TK construct with thyroid-specific promoter: enhancement of activity and specificity with histone deacetylase inhibitors and agents modulating the camp pathway.
Thyroid Neoplasms
Adenovirus HSV-TK construct with thyroid-specific promoter: enhancement of activity and specificity with histone deacetylase inhibitors and agents modulating the camp pathway.
Ca2+-dependent regulation of calcitonin gene expression by the transcriptional repressor DREAM.
Construction of gene therapy vectors targeting thyroid cells: enhancement of activity and specificity with histone deacetylase inhibitors and agents modulating the cyclic adenosine 3',5'-monophosphate pathway and demonstration of activity in follicular and anaplastic thyroid carcinoma cells.
Downregulation of TSPAN13 by miR-369-3p inhibits cell proliferation in papillary thyroid cancer (PTC).
Effects of CDK6 regulated by miR-298 on proliferation and apoptosis of thyroid cancer cells.
Generation and identification of a thyroid cancer cell line with stable expression of CCDC67 and luciferase reporter genes.
LncRNA FOXD2-AS1 Functions as a Competing Endogenous RNA to Regulate TERT Expression by Sponging miR-7-5p in Thyroid Cancer.
Long Noncoding RNA CCDC26 Promotes Thyroid Cancer Malignant Progression via miR-422a/EZH2/Sirt6 Axis.
MicroRNA?126 is downregulated in thyroid cancer cells, and regulates proliferation, migration and invasion by targeting CXCR4.
miR-424-5p Promotes Anoikis Resistance and Lung Metastasis by Inactivating Hippo Signaling in Thyroid Cancer.
MiR-539 inhibits thyroid cancer cell migration and invasion by directly targeting CARMA1.
Molecular cloning of a functional promoter of the human plakoglobin gene.
Notch signaling is involved in expression of thyrocyte differentiation markers and is down-regulated in thyroid tumors.
Protein synthesis inhibitors, in synergy with 5-azacytidine, restore sodium/iodide symporter gene expression in human thyroid adenoma cell line, KAK-1, suggesting trans-active transcriptional repressor.
Regulatory Single Nucleotide Polymorphism Increases TERT Promoter Activity in Thyroid Carcinoma Cells.
ZFPM2-AS1 transcriptionally mediated by STAT1 regulates thyroid cancer cell growth, migration and invasion via miR-515-5p/TUSC3.
Toxoplasmosis
Seroprevalence of toxoplasmosis among reproductive-aged women in Myanmar and evaluation of luciferase immunoprecipitation system assay.
Triple Negative Breast Neoplasms
Angiotensin II promotes primary tumor growth and metastasis formation of murine TNBC 4T1 cells through the fibroblasts around cancer cells.
Aptamer-guided siRNA-loaded nanomedicines for systemic gene silencing in CD-44 expressing murine triple-negative breast cancer model.
Bioluminescence Imaging-Based Assessment of the Anti-Triple-Negative Breast Cancer and NF-Kappa B Pathway Inhibition Activity of Britanin.
Establishment of a bioluminescent MDA-MB-231 cell line for human triple-negative breast cancer research.
Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6-Abundant Breast Cancer Cells by Regulating ?-Secretase-Mediated Notch1 Activation in Caveolae.
MicroRNA-150 suppresses triple-negative breast cancer metastasis through targeting HMGA2.
[Constraction of triple negative breast cancer cell model containing EGFR promoter and luciferase reporter gene].
[Establishment of a bioluminescent MDA-MB-231 cell line for in vivo imaging of human triple-negative breast cancer xenograft].
Trophoblastic Neoplasms
Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains.
Tuberculosis
A rapid method for screening antimicrobial agents for activities against a strain of Mycobacterium tuberculosis expressing firefly luciferase.
A rapid, low pH, nutrient stress, assay to determine the bactericidal activity of compounds against non-replicating Mycobacterium tuberculosis.
Anti-tubercular and probiotic properties of coagulase-negative staphylococci isolated from Koozh, a traditional fermented food of South India.
Assessment of immunity to mycobacterial infection with luciferase reporter constructs.
Assessment of in vitro immunity to Mycobacterium tuberculosis in a human peripheral blood infection model using a luciferase reporter construct of M. tuberculosis H37Rv.
Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains.
Bacterial luciferase is naturally destabilized in Mycobacterium tuberculosis and can be used to monitor changes in gene expression.
Bioactive Potential of Actinomycetes from Less Explored Ecosystems against Mycobacterium tuberculosis and Other Nonmycobacterial Pathogens.
Bioluminescence screening in vitro (Bio-Siv) assays for high-volume antimycobacterial drug discovery.
Characterization of temperate phage Che12 and construction of a new tool for diagnosis of tuberculosis.
Conditionally replicating luciferase reporter phages: improved sensitivity for rapid detection and assessment of drug susceptibility of Mycobacterium tuberculosis.
Construction of D29 shuttle phasmids and luciferase reporter phages for detection of mycobacteria.
Detection and drug-susceptibility testing of M. tuberculosis from sputum samples using luciferase reporter phage: comparison with the Mycobacteria Growth Indicator Tube (MGIT) system.
Enhancement of anti-tubercular activity and biomass of fermented food associated Staphylococcus hominis strain MANF2 using Taguchi orthogonal array and Box-Behnken design.
Establishing Virulence Associated Polyphosphate Kinase 2 as a drug target for Mycobacterium tuberculosis.
Evaluation of a semi-automated reporter phage assay for susceptibility testing of Mycobacterium tuberculosis isolates in South Africa.
Exploration of Synergistic Action of Cell Wall-Degrading Enzymes against Mycobacterium tuberculosis.
Human immunodeficiency virus type 1 protease inhibitors block toll-like receptor 2 (TLR2)- and TLR4-Induced NF-kappaB activation.
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
Luciferase reporter mycobacteriophages for detection, identification, and antibiotic susceptibility testing of Mycobacterium tuberculosis in Mexico.
Luciferase reporter phage phAE85 for rapid detection of rifampicin resistance in clinical isolates of Mycobacterium tuberculosis.
Microplate Alamar Blue Assay (MABA) and Low Oxygen Recovery Assay (LORA) for Mycobacterium tuberculosis.
Microwave-assisted synthesis, molecular docking and antitubercular activity of 1,2,3,4-tetrahydropyrimidine-5-carbonitrile derivatives.
Mycobacterium tuberculosis mannose-capped lipoarabinomannan can induce NF-kappaB-dependent activation of human immunodeficiency virus type 1 long terminal repeat in T cells.
Mycobacterium tuberculosis Rv2185c contributes to nuclear factor-?B activation.
Phage lysin to control the overgrowth of normal flora in processed sputum samples for the rapid and sensitive detection of Mycobacterium tuberculosis by luciferase reporter phage assay.
Phage lysin to supplement phagebiotics to decontaminate processed sputum specimens.
Photographic and luminometric detection of luciferase reporter phages for drug susceptibility testing of clinical Mycobacterium tuberculosis isolates.
Production and purification of anti-tubercular and anticancer protein from Staphylococcus hominis under mild stress condition of Mentha piperita L.
Purification and characterization of anti-tubercular and anticancer protein from Staphylococcus hominis strain MANF2: In silico structural and functional insight of peptide.
Rapid assessment of drug susceptibilities of Mycobacterium tuberculosis by means of luciferase reporter phages.
Rapid film-based determination of antibiotic susceptibilities of Mycobacterium tuberculosis strains by using a luciferase reporter phage and the Bronx Box.
Rapid identification and susceptibility testing of Mycobacterium tuberculosis from MGIT cultures with luciferase reporter mycobacteriophages.
Reduced expression of nuclear cyclic adenosine 5'-monophosphate response element-binding proteins and IFN-gamma promoter function in disease due to an intracellular pathogen.
Selective Killing of Dormant Mycobacterium tuberculosis by Marine Natural Products.
Serological diagnosis of pulmonary Mycobacterium tuberculosis infection by LIPS using a multiple antigen mixture.
Specific identification of Mycobacterium tuberculosis with the luciferase reporter mycobacteriophage: use of p-nitro-alpha-acetylamino-beta-hydroxy propiophenone.
Synthesis and anti-tubercular and antimicrobial activities of some 2r,4c-diaryl-3-azabicyclo[3.3.1]nonan-9-one N-isonicotinoylhydrazone derivatives.
Synthesis of quinoline coupled [1,2,3]-triazoles as a promising class of anti-tuberculosis agents.
Tape measure protein having MT3 motif facilitates phage entry into stationary phase cells of Mycobacterium tuberculosis.
The Mycobacterium tuberculosis katG promoter region contains a novel upstream activator.
Tuberous Sclerosis
MiR-451 is decreased in hypertrophic cardiomyopathy and regulates autophagy by targeting TSC1.
Ureteral Obstruction
A sensitive short-term evaluation of antifibrotic effects using newly established type I collagen reporter transgenic rats.
Urinary Bladder Neoplasms
A novel gene expression system for detecting viable bladder cancer cells.
Circ0001429 regulates progression of bladder cancer through binding miR-205-5p and promoting VEGFA expression.
circCEP128 Knockdown Suppresses Bladder Cancer Progression via Regulating microRNA-515-5p/SDC1 Axis.
circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-?2/smad3 pathway.
Circular RNA RBPMS inhibits bladder cancer progression via miR-330-3p/RAI2 regulation.
Expression and regulation of tumor suppressor gene maspin in human bladder cancer.
LncRNA MT1JP functions as a tumor suppressor via regulating miR-214-3p expression in bladder cancer.
LncRNA ZNFX1-AS1 targeting miR-193a-3p/SDC1 regulates cell proliferation, migration and invasion of bladder cancer cells.
microRNA response elements-regulated TRAIL expression shows specific survival-suppressing activity on bladder cancer.
MicroRNA-101 inhibits the proliferation and invasion of bladder cancer cells via targeting c-FOS.
MicroRNA-124-3p suppresses cell migration and invasion by targeting ITGA3 signaling in bladder cancer.
MicroRNA-1246 regulates the radio-sensitizing effect of curcumin in bladder cancer cells via activating P53.
microRNA-125b inhibits cell migration and invasion by targeting matrix metallopeptidase 13 in bladder cancer.
MicroRNA-125b suppresses the development of bladder cancer by targeting E2F3.
MicroRNA-1280 inhibits invasion and metastasis by targeting ROCK1 in bladder cancer.
MicroRNA-133 inhibits cell proliferation, migration and invasion by targeting epidermal growth factor receptor and its downstream effector proteins in bladder cancer.
microRNA-18a, a member of the oncogenic miR-17-92 cluster, targets Dicer and suppresses cell proliferation in bladder cancer T24 cells.
microRNA-195 inhibits cell proliferation in bladder cancer via inhibition of cell division control protein 42 homolog/signal transducer and activator of transcription-3 signaling.
microRNA-203 suppresses bladder cancer development by repressing bcl-w expression.
MicroRNA-23b functions as a tumor suppressor by regulating Zeb1 in bladder cancer.
MicroRNA-335 is downregulated in bladder cancer and inhibits cell growth, migration and invasion via targeting ROCK1.
MicroRNA-34a functions as an anti-metastatic microRNA and suppresses angiogenesis in bladder cancer by directly targeting CD44.
MicroRNA-374a Inhibits Aggressive Tumor Biological Behavior in Bladder Carcinoma by Suppressing Wnt/?-Catenin Signaling.
MicroRNA-490-5p inhibits proliferation of bladder cancer by targeting c-Fos.
microRNA-99a inhibiting cell proliferation, migration and invasion by targeting fibroblast growth factor receptor 3 in bladder cancer.
MicroRNA?539 inhibits the proliferation and invasion of bladder cancer cells by regulating IGF?1R.
miR-1-3p Contributes to Cell Proliferation and Invasion by Targeting Glutaminase in Bladder Cancer Cells.
MiR-103/107 induces tumorigenicity in bladder cancer cell by suppressing PTEN.
Mir-135a enhances cellular proliferation through post-transcriptionally regulating PHLPP2 and FOXO1 in human bladder cancer.
miR-199a-5p suppresses human bladder cancer cell metastasis by targeting CCR7.
miR-200c Inhibits invasion, migration and proliferation of bladder cancer cells through down-regulation of BMI-1 and E2F3.
miR-221 facilitates the TGFbeta1-induced epithelial-mesenchymal transition in human bladder cancer cells by targeting STMN1.
MiR-5195-3p inhibits proliferation and invasion of human bladder cancer cells by directly targeting oncogene KLF5.
miR-9 promotes cell proliferation and inhibits apoptosis by targeting LASS2 in bladder cancer.
Nucleic Acid Targeted Therapy: G4 Oligonucleotides Downregulate HRAS in Bladder Cancer Cells through a Decoy Mechanism.
Oncogenic miRNA-182-5p targets Smad4 and RECK in human bladder cancer.
Optimum conditions of ultrasound-mediated destruction of bubble liposome for siRNA transfer in bladder cancer.
Short rare minisatellite variant of BORIS-MS2 is related to bladder cancer susceptibility.
Synthesizing AND gate genetic circuits based on CRISPR-Cas9 for identification of bladder cancer cells.
Synthetic miRNA sponges driven by mutant hTERT promoter selectively inhibit the progression of bladder cancer.
Systemic Immunotherapy of Non-Muscle Invasive Mouse Bladder Cancer with Avelumab, an Anti-PD-L1 Immune Checkpoint Inhibitor.
Targeting immunotherapy for bladder cancer by using anti-CD3 × CD155 bispecific antibody.
Targeting immunotherapy for bladder cancer using anti-CD3× B7-H3 bispecific antibody.
The Antineoplastic Activity of Photothermal Ablative Therapy with Targeted Gold Nanorods in an Orthotopic Urinary Bladder Cancer Model.
The role of Lutheran/basal cell adhesion molecule in human bladder carcinogenesis.
Tumor suppressor microRNA-493 decreases cell motility and migration ability in human bladder cancer cells by downregulating RhoC and FZD4.
Upregulation of long non-coding RNA urothelial carcinoma associated 1 by CCAAT/enhancer binding protein ? contributes to bladder cancer cell growth and reduced apoptosis.
Validating bladder cancer xenograft bioluminescence with magnetic resonance imaging: the significance of hypoxia and necrosis.
Welfare Assessment following Heterotopic or Orthotopic Inoculation of Bladder Cancer in C57BL/6 Mice.
[Effect of mouse uroplakin II promoter on human bladder cancer cell line]
[Establishment of a human bladder cancer cell line stably co-expressing hSPRY2 and luciferase genes and its subcutaneous tumor xenograft model in nude mice].
Uterine Cervical Neoplasms
Absence of EpCAM in cervical cancer cells is involved in sluginduced epithelial-mesenchymal transition.
Aldehyde dehydrogenase 1, a target of miR-222, is expressed at elevated levels in cervical cancer.
Androgen Receptor Regulation of the Versican Gene through an Androgen Response Element in the Proximal Promoter.
Bax-induced apoptosis as a novel gene therapy approach for carcinoma of the cervix.
CD14 protein acts as an adaptor molecule for the immune recognition of Salmonella curli fibers.
CircNEIL3 promotes cervical cancer cell proliferation by adsorbing miR-137 and upregulating KLF12.
Comparison of transfection efficiency of nonviral gene transfer reagents.
Conditionally replicating E1B-deleted adenovirus driven by the squamous cell carcinoma antigen 2 promoter for uterine cervical cancer therapy.
Construction of artificial promoters sensitively responsive to sonication in vitro.
DARS-AS1 Knockdown Inhibits the Growth of Cervical Cancer Cells via Downregulating HMGB1 via Sponging miR-188-5p.
Down-regulation of HPGD by miR-146b-3p promotes cervical cancer cell proliferation, migration and anchorage-independent growth through activation of STAT3 and AKT pathways.
Evaluation of tissue-specific promoters in carcinomas of the cervix uteri.
hTERT promoter activity and CpG methylation in HPV-induced carcinogenesis.
Inhibiting the redox function of APE1 suppresses cervical cancer metastasis via disengagement of ZEB1 from E-cadherin in EMT.
LINC00707 Regulates miR-382-5p/VEGFA Pathway to Enhance Cervical Cancer Progression.
Lnc-SNHG16/miR-128 axis modulates malignant phenotype through WNT/?-catenin pathway in cervical cancer cells.
LncRNA SNHG20 promotes cell proliferation and invasion via miR-140-5p-ADAM10 axis in cervical cancer.
MicroRNA-101-5p inhibits the growth and metastasis of cervical cancer cell by inhibiting CXCL6.
MicroRNA-10b inhibits proliferation, migration and invasion in cervical cancer cells via direct targeting of insulin-like growth factor-1 receptor.
MicroRNA-138 inhibits proliferation of cervical cancer cells by targeting c-Met.
MicroRNA-143 regulates cell migration and invasion by targeting GOLM1 in cervical cancer.
MicroRNA-145 sensitizes cervical cancer cells to low-dose irradiation by downregulating OCT4 expression.
MicroRNA-148a-3p inhibits the proliferation of cervical cancer cells by regulating the expression levels of DNMT1 and UTF1.
microRNA-150 promotes cervical cancer cell growth and survival by targeting FOXO4.
MicroRNA-196a promotes cervical cancer proliferation through the regulation of FOXO1 and p27(Kip1.).
MicroRNA-362 is downregulated in cervical cancer and inhibits cell proliferation, migration and invasion by directly targeting SIX1.
MicroRNA-373 functions as an oncogene and targets YOD1 gene in cervical cancer.
MicroRNA-425 induces apoptosis and suppresses migration and invasion of human cervical cancer cells by targeting RAB2B.
MicroRNA-432 is downregulated in cervical cancer and directly targets FN1 to inhibit cell proliferation and invasion.
microRNA-499a promotes the progression and chemoresistance of cervical cancer cells by targeting SOX6.
MicroRNA-664 suppresses the growth of cervical cancer cells via targeting c-Kit.
MicroRNA-7-5p Promotes Cisplatin Resistance of Cervical Cancer Cells and Modulation of Cellular Energy Homeostasis by Regulating the Expression of the PARP-1 and BCL2 Genes.
MicroRNA?195 inhibits cell proliferation, migration and invasion by targeting defective in cullin neddylation 1 domain containing 1 in cervical cancer.
MicroRNA?485 targets MACC1 and inhibits cervical cancer cell proliferation and invasion.
miR-126-5p Restoration Promotes Cell Apoptosis in Cervical Cancer by Targeting Bcl2l2.
miR-133a inhibits cervical cancer growth by targeting EGFR.
Mir-155 promotes cervical cancer cell proliferation through suppression of its target gene LKB1.
MiR-181a Promotes Apoptosis and Reduces Cisplatin Resistance by Inhibiting Osteopontin in Cervical Cancer Cells.
miR-185-3p targets Annexin-A8 to inhibit proliferation in cervical cancer cells.
miR-187 inhibits tumor growth and invasion by directly targeting MAPK12 in osteosarcoma.
MiR-195 Suppresses Cervical Cancer Migration and Invasion Through Targeting Smad3.
miR-205 Promotes Apoptosis of Cervical Cancer Cells and Enhances Drug Sensitivity of Cisplatin by Inhibiting YAP1.
miR-20a inhibits the killing effect of natural killer cells to cervical cancer cells by downregulating RUNX1.
miR-376c inhibits cervical cancer cell proliferation and invasion by targeting BMI1.
miR-587 promotes cervical cancer by repressing interferon regulatory factor 6.
miR-92a promotes cervical cancer cell proliferation, invasion, and migration by directly targeting PIK3R1.
miR?802 inhibits the epithelial?mesenchymal transition, migration and invasion of cervical cancer by regulating BTF3.
MiRNA-338-3p regulates cervical cancer cells proliferation by targeting MACC1 through MAPK signaling pathway.
miRNA-641 inhibits the proliferation, migration, and invasion and induces apoptosis of cervical cancer cells by directly targeting ZEB1.
NF-YA promotes the cell proliferation and tumorigenic properties by transcriptional activation of SOX2 in cervical cancer.
Precise engineering of siRNA delivery vehicles to tumors using polyion complexes and gold nanoparticles.
Promoter activity of SARS coronavirus 5' UTR sequence in eukaryotic cells.
Reciprocal transactivation of Merkel cell polyomavirus and high-risk human papillomavirus promoter activities and increased expression of their oncoproteins.
Repression of HPV E6-activated RSV promoter activity by anti-cancer agents.
Ropivacaine inhibits cervical cancer cell growth via suppression of the miR?96/MEG2/pSTAT3 axis.
Silencing of long non-coding RNA NCK1-AS1 inhibits cell proliferation and migration via inhibition of microRNA-134 in cervical cancer.
Suppression of hypoxia-inducible factor 1? (HIF-1?) by tirapazamine is dependent on eIF2? phosphorylation rather than the mTORC1/4E-BP1 pathway.
Tanshinone I attenuates proliferation and chemoresistance of cervical cancer in a KRAS-dependent manner.
The cloning and activity of human Hes1 gene promoter.
Using ?-Lactamase and NanoLuc Luciferase Reporter Gene Assays to Identify Inhibitors of the HIF-1 Signaling Pathway.
[CDH1 polymorphism and its association with the risk of cervical cancer]
[Proliferation of MicroRNA-365 and E74-like Factor 4 in Cervical Cancer Cells and Its Clinical Significance].
Uterine Neoplasms
Transcriptional activity of the tandem repeat polymorphism in the 5'-flanking region of the human CYP2E1 gene.
Uveitis
Bioluminescence for in vivo detection of cell-type-specific inflammation in a mouse model of uveitis.
Vaccinia
A synthetic vaccinia virus promoter with enhanced early and late activity.
Application of bioluminescence imaging to the prediction of lethality in vaccinia virus-infected mice.
Cascade regulation of vaccinia virus gene expression is modulated by multistage promoters.
Demonstration of the specificity of poliovirus encapsidation using a novel replicon which encodes enzymatically active firefly luciferase.
Development of an animal model of progressive vaccinia in nu/nu mice and the use of bioluminescence imaging for assessment of the efficacy of monoclonal antibodies against vaccinial B5 and L1 proteins.
Highly attenuated vaccinia virus mutants for the generation of safe recombinant viruses.
Inhibition of toll-like receptor signaling in primary murine microglia.
Interferon treatment inhibits early events in vaccinia virus gene expression in infected mice.
Lethality in mice infected with recombinant vaccinia virus expressing hepatitis C virus core protein.
Measurements of vaccinia virus dissemination using whole body imaging: approaches for predicting of lethality in challenge models and testing of vaccines and antiviral treatments.
Molluscum Contagiosum Virus Transcriptome in Abortively Infected Cultured Cells and Human Skin Lesion.
Mutational analysis of poliovirus 2Apro. Distinct inhibitory functions of 2apro on translation and transcription.
New method for the assessment of molluscum contagiosum virus infectivity.
Passive Immunotherapies Protect WRvFire and IHD-J-Luc Vaccinia Virus-Infected Mice from Lethality by Reducing Viral Loads in the Upper Respiratory Tract and Internal Organs.
Real-time imaging of tumors using replication-competent light-emitting microorganisms.
Role of NH(2)- and COOH-terminal domains of the P protein of human parainfluenza virus type 3 in transcription and replication.
Vaccinia virus preferentially enters polarized epithelial cells through the basolateral surface.
[Expression of the glow worm luciferase gene in mammalian cells using vectors based on vaccinia viruses]
Ventricular Fibrillation
Variants in the SCN5A Promoter Associated With Various Arrhythmia Phenotypes.
Vesicular Stomatitis
Characterization of cell-surface determinants important for baculovirus infection.
Computational and Experimental Studies Reveal That Thymoquinone Blocks the Entry of Coronaviruses Into In Vitro Cells.
Functional expression of mouse relaxin and mouse relaxin-3 in the lung from an Ebola virus glycoprotein-pseudotyped lentivirus via tracheal delivery.
Hepatitis C virus: The role of molecular mimicry in response to interferon treatment.
Human immunodeficiency virus type 1 uses lipid raft-colocalized CD4 and chemokine receptors for productive entry into CD4(+) T cells.
Human T-cell leukemia virus type-I (HTLV-I) tax is not the only one factor to enhance human immunodeficiency virus type-I (HIV-1) infection in culture-supernatants.
Middle East respiratory coronavirus (MERS-CoV) spike (S) protein vesicular stomatitis virus pseudoparticle neutralization assays offer a reliable alternative to the conventional neutralization assay in human seroepidemiological studies.
Monitoring Viral Entry in Real-Time Using a Luciferase Recombinant Vesicular Stomatitis Virus Producing SARS-CoV-2, EBOV, LASV, CHIKV, and VSV Glycoproteins.
Preparation of vesicular stomatitis virus pseudotype with Chikungunya virus envelope protein.
Reduced HIV-1 long terminal repeat transcription in subjects with protective interferon regulatory factor-1 genotype: a potential mechanism mediating resistance to infection by HIV-1.
The maturation of dendritic cells results in postintegration inhibition of HIV-1 replication.
The NRTIs lamivudine, stavudine and zidovudine have reduced HIV-1 inhibitory activity in astrocytes.
Towards Human Translation of Lentiviral Airway Gene Delivery for Cystic Fibrosis: A One-Month CFTR and Reporter Gene Study in Marmosets.
Tumour necrosis factor-alpha stimulates HIV-1 replication in single-cycle infection of human term placental villi fragments in a time, viral dose and envelope dependent manner.
Viral-mediated fusion of mesenchymal stem cells with cells of the infarcted heart hinders healing via decreased vascularization and immune modulation.
Vibrio Infections
The 9H-Fluoren Vinyl Ether Derivative SAM461 Inhibits Bacterial Luciferase Activity and Protects Artemia franciscana From Luminescent Vibriosis.
Virus Diseases
A NanoLuc Luciferase Reporter Pseudorabies Virus for Live Imaging and Quantification of Viral Infection.
A sensitive and versatile bioluminescence bioassay for HIV type 1 based on adenoviral vectors.
Applications of bioluminescence imaging to antiviral research and therapy: Multiple luciferase enzymes and quantitation.
Bioluminescence Imaging as a Tool for Poxvirus Biology.
Bioluminescence imaging of reporter mice for studies of infection and inflammation.
Cell Cultures for Virology: Usability, Advantages, and Prospects.
Cell-free HIV type 1 infection is restricted in the human trophoblast choriocarcinoma BeWo cell line, even with expression of CD4, CXCR4 and CCR5.
Characterization of the early steps of hepatitis C virus infection by using luciferase reporter viruses.
CIRP promotes the progression of non-small cell lung cancer through activation of Wnt/?-catenin signaling via CTNNB1.
Comparison of monkeypox viruses pathogenesis in mice by in vivo imaging.
Complex Regulation Pattern of IRF3 Activation Revealed by a Novel Dimerization Reporter System.
Contribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear import.
Determination of neutralization activities by a new versatile assay using an HIV-1 genome carrying the Gaussia luciferase gene.
Differential response of the Senegalese sole (Solea senegalensis) Mx promoter to viral infections in two salmonid cell lines.
Epstein-Barr virus LF2: an antagonist to type I interferon.
Evaluation of a range of mammalian and mosquito cell lines for use in Chikungunya virus research.
Firefly luciferase, synthesized to very high levels in caterpillars infected with a recombinant baculovirus, can also be used as an efficient reporter enzyme in vivo.
Generation and Characterization of recombinant SARS-CoV-2 expressing reporter genes.
Generation of recombinant rabies viruses encoding NanoLuc luciferase for antiviral activity assays.
Highly sensitive real-time in vivo imaging of an influenza reporter virus reveals dynamics of replication and spread.
Human kinome analysis reveals novel kinases contributing to virus infection and retinoic-acid inducible gene I-induced type I and type III IFN gene expression.
ICAM-1 regulates the survival of influenza virus in lung epithelial cells during the early stages of infection.
Imaging immediate-early and strict-late promoter activity during oncolytic herpes simplex virus type 1 infection and replication in tumors.
Imaging of light emission from the expression of luciferases in living cells and organisms: a review.
Infectivity of attenuated poxvirus vaccine vectors and immunogenicity of a raccoonpox vectored rabies vaccine in the Brazilian Free-tailed bat (Tadarida brasiliensis).
Interferon treatment inhibits early events in vaccinia virus gene expression in infected mice.
Luciferase imaging of a neurotropic viral infection in intact animals.
MicroRNA 34a contributes to virus-mediated apoptosis through binding to its target gene Bax in influenza A virus infection.
Nanobody-based sandwich reporter system for living cell sensing influenza A virus infection.
Peptides that mimic the amino-terminal end of the rabies virus phosphoprotein have antiviral activity.
Protamine sulfate enhances the transduction efficiency of recombinant adeno-associated virus-mediated gene delivery.
Proteins are cointernalized with virion particles during early infection.
Redirected infection of directly biotinylated recombinant adenovirus vectors through cell surface receptors and antigens.
The HSV-1 Latency-Associated Transcript Functions to Repress Latent Phase Lytic Gene Expression and Suppress Virus Reactivation from Latently Infected Neurons.
Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein.
Utilization of Replication-Competent XMRV Reporter-Viruses Reveals Severe Viral Restriction in Primary Human Cells.
Vaccinia virus preferentially enters polarized epithelial cells through the basolateral surface.
Visualizing influenza virus infection in living mice.
Warts
Low doses of flagellin-L2 multimer vaccines protect against challenge with diverse papillomavirus genotypes.
West Nile Fever
Dicer-2-dependent activation of Culex Vago occurs via the TRAF-Rel2 signaling pathway.
Transcriptional regulation of major histocompatibility complex class I by flavivirus West Nile is dependent on NF-kappaB activation.
Whooping Cough
Comparison of functional profiles at human recombinant somatostatin sst2 receptor: simultaneous determination of intracellular Ca2+ and luciferase expression in CHO-K1 cells.
Constitutive activation of NF-kappa B and secretion of interleukin-8 induced by the G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus involve G alpha(13) and RhoA.
Functional analysis of the D2L dopamine receptor expressed in a cAMP-responsive luciferase reporter cell line.
Label-free versus conventional cellular assays: Functional investigations on the human histamine H1 receptor.
Pharmacological characterisation of the goldfish somatostatin sst5 receptor.
Regulation of p42/p44 mitogen-activated protein kinase by the human adenosine A3 receptor in transfected CHO cells.
The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids.
Wilms Tumor
LINC00858 facilitates the malignant development of Wilms' tumor by targeting miR-653-5p.
LncRNA CRNDE promotes the development of Wilms' tumor by regulating microRNA-424.
MicroRNA-193a inhibits breast cancer proliferation and metastasis by downregulating WT1.
miR-140-5p could suppress tumor proliferation and progression by targeting TGFBRI/SMAD2/3 and IGF-1R/AKT signaling pathways in Wilms' tumor.
miR-200c-3p Suppresses the Proliferative, Migratory, and Invasive Capacities of Nephroblastoma Cells via Targeting FRS2.
miR-378c suppresses Wilms tumor development via negatively regulating CAMKK2.
Positive and negative regulatory regions in promoters of human glutathione transferase alpha genes.
The 5' flanking region of the human bone morphogenetic protein-7 gene.
Transcriptional repression of catalase in mouse skin tumor progression.
[Effect of piRNA NU13 in regulating biological behaviors of human Wilms tumor cells in vitro].
Yellow Fever
Generation and Application of a Luciferase Reporter Virus Based on Yellow Fever Virus 17D.
High-throughput neutralization assay for multiple flaviviruses based on single-round infectious particles using dengue virus type 1 reporter replicon.
Yersinia Infections
In vivo analysis of Yersinia enterocolitica infection using luxCDABE.