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Information on EC 1.14.14.175 - ferruginol synthase and Organism(s) Rosmarinus officinalis and UniProt Accession A0A0C5Q4Y6

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EC Tree
IUBMB Comments
A cytochrome P-450 (heme thiolate) enzyme found in some members of the Lamiaceae (mint family). The enzyme from Rosmarinus officinalis (rosemary) is involved in biosynthesis of carnosic acid, while the enzyme from the Chinese medicinal herb Salvia miltiorrhiza is involved in the biosynthesis of the tanshinones, abietane-type norditerpenoid naphthoquinones that are the main lipophilic bioactive components found in the plant.
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Rosmarinus officinalis
UNIPROT: A0A0C5Q4Y6
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Word Map
The enzyme appears in selected viruses and cellular organisms
Synonyms
cyp76ah1, cyp76ah24, cyp76ah4, ferruginol synthase, miltiradiene oxidase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
CYP76AH1
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SYSTEMATIC NAME
IUBMB Comments
abieta-8,11,13-triene,[reduced NADPH-hemoprotein reductase]:oxygen 12-oxidoreductase (ferruginol-forming)
A cytochrome P-450 (heme thiolate) enzyme found in some members of the Lamiaceae (mint family). The enzyme from Rosmarinus officinalis (rosemary) is involved in biosynthesis of carnosic acid, while the enzyme from the Chinese medicinal herb Salvia miltiorrhiza is involved in the biosynthesis of the tanshinones, abietane-type norditerpenoid naphthoquinones that are the main lipophilic bioactive components found in the plant.
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
C76H2_ROSOF
493
1
56009
Swiss-Prot
Secretory Pathway (Reliability: 4)