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Information on EC 1.1.1.26 - glyoxylate reductase and Organism(s) Saccharolobus solfataricus and UniProt Accession Q97U35

for references in articles please use BRENDA:EC1.1.1.26
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EC Tree
     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.26 glyoxylate reductase
IUBMB Comments
Reduces glyoxylate to glycolate or hydroxypyruvate to D-glycerate.
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This record set is specific for:
Saccharolobus solfataricus
UNIPROT: Q97U35
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Word Map
The taxonomic range for the selected organisms is: Saccharolobus solfataricus
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
grhpr, glyoxylate reductase, glyr1, glyoxylate reductase/hydroxypyruvate reductase, glyr2, glyoxylate/hydroxypyruvate reductase, nadh-dependent glyoxylate reductase, nadh-glyoxylate reductase, glyoxylic acid reductase, succinic semialdehyde/glyoxylate reductase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
glycolate oxidase
-
-
-
-
glyoxylic acid reductase
-
-
-
-
NADH-dependent glyoxylate reductase
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-
-
-
NADH-glyoxylate reductase
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-
-
-
reductase, glyoxylate
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
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-
-
-
reduction
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-
-
-
SYSTEMATIC NAME
IUBMB Comments
glycolate:NAD+ oxidoreductase
Reduces glyoxylate to glycolate or hydroxypyruvate to D-glycerate.
CAS REGISTRY NUMBER
COMMENTARY hide
9028-32-4
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
glyoxylate + NADH + H+
glycolate + NAD+
show the reaction diagram
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-
-
?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
5
glyoxylate
pH 7.5, 70°C, recombinant enzyme and native enzyme from xylose-grown cell extract
0.1
NADH
pH 7.5, 70°C, recombinant enzyme and native enzyme from xylose-grown cell extract
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Nunn, C.E.; Johnsen, U.; Schoenheit, P.; Fuhrer, T.; Sauer, U.; Hough, D.W.; Danson, M.J.
Metabolism of pentose sugars in the hyperthermophilic archaea Sulfolobus solfataricus and Sulfolobus acidocaldarius
J. Biol. Chem.
285
33701-33709
2010
Saccharolobus solfataricus (Q97U35), Saccharolobus solfataricus P2 (Q97U35)
Manually annotated by BRENDA team