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Information on EC 1.1.1.219 - dihydroflavonol 4-reductase and Organism(s) Gerbera hybrida and UniProt Accession P51105

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IUBMB Comments
This plant enzyme, involved in the biosynthesis of anthocyanidins, is known to act on (+)-dihydrokaempferol, (+)-taxifolin, and (+)-dihydromyricetin, although some enzymes may act only on a subset of these compounds. Each dihydroflavonol is reduced to the corresponding cis-flavan-3,4-diol. NAD+ can act instead of NADP+, but more slowly.
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This record set is specific for:
Gerbera hybrida
UNIPROT: P51105
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
dihydroflavonol 4-reductase, flavonoid 3'-hydroxylase, dihydroflavonol reductase, dihydroflavonol-4-reductase, csdfr, tadfr, mcdfr, brdfr1, bo9g058630, pgdfr, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
DFR
-
-
-
-
DHM reductase
-
-
-
-
DHQ reductase
-
-
-
-
dihydroflavanol 4-reductase
-
-
-
-
dihydrokaempferol 4-reductase
-
-
-
-
dihydromyricetin reductase
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-
-
-
dihydroquercetin reductase
-
-
-
-
NADPH-dihydromyricetin reductase
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-
-
-
reductase, dihydromyricetin
-
-
-
-
reductase, dihydroquercetin
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-
-
-
TRANSPARENT TESTA 3 protein
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
-
-
-
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oxidation
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-
-
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reduction
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-, -
SYSTEMATIC NAME
IUBMB Comments
(2R,3S,4S)-leucoanthocyanidin:NADP+ 4-oxidoreductase
This plant enzyme, involved in the biosynthesis of anthocyanidins, is known to act on (+)-dihydrokaempferol, (+)-taxifolin, and (+)-dihydromyricetin, although some enzymes may act only on a subset of these compounds. Each dihydroflavonol is reduced to the corresponding cis-flavan-3,4-diol. NAD+ can act instead of NADP+, but more slowly.
CAS REGISTRY NUMBER
COMMENTARY hide
83682-99-9
-
98668-58-7
-
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
DFRA_GERHY
366
1
41102
Swiss-Prot
other Location (Reliability: 3)