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Information on EC 1.1.1.166 - hydroxycyclohexanecarboxylate dehydrogenase

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IUBMB Comments
Acts on hydroxycyclohexanecarboxylates that have an equatorial carboxy group at C-1, an axial hydroxy group at C-3 and an equatorial hydroxy or carbonyl group at C-4, including (-)-quinate and (-)-shikimate.
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The expected taxonomic range for this enzyme is: Lactobacillus plantarum
Synonyms
(-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD oxidoreductase, dihydroxycyclohexanecarboxylate dehydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD+ = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + NADH + H+
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Acts on hydroxycyclohexanecarboxylates that have an equatorial carboxyl group at C-1, an axial hydroxyl group at C-3 and an equatorial hydroxyl group or carbonyl group at C-4, including (-)-quinate and (-)-shikimate
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