Sequence of PEPA_MACMU
EC Number:3.4.23.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Preferential cleavage: hydrophobic, preferably aromatic, residues in P1 and P1' positions. Cleaves Phe1-/-Val, Gln4-/-His, Glu13-/-Ala, Ala14-/-Leu, Leu15-/-Tyr, Tyr16-/-Leu, Gly23-/-Phe, Phe24-/-Phe and Phe25-/-Tyr bonds in the B chain of insulin
Other sequences found for EC No. 3.4.23.1
General information:
Sequence
0 MKWLLLLGLV ALSECIIYKV PLVRKKSLRR NLSEHGLLKD FLKKHNRNPA SKYFPQTEAP
60 TLIDEQPLEN YLDVEYFGTI GIGTPAQDFT VIFDTGSSNL WVPSVYCSSL ACTNHNLFNP
120 QDSSTYQSTS GTLSITYGTG SMTGILGYDT VQVGGISDTN QIFGLSETEP GSFLYYAPFD
180 GILGLAYPSI SSSGATPVFD NIWDQGLVSQ DLFSVYLSAD DQSGSVVIFG GIDSSYYTGS
240 LNWVPVSVEG YWQISVDSIT MNGEAIACAE GCQAIVDTGT SLLTGPTSPI ANIQSDIGAS
300 ENSDGEMVVS CSAISSLPDI VFTINGVQYP LPPSAYILQS QGSCTSGFQG MDVPTESGEL
360 WILGDVFIRQ YFTVFDRANN QVGLAPVA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
332520
Evers M.P.J.,Zelle B.,Bebelman J.-P.,Pronk J.C.,Mager W.H.,Planta R.J.,Eriksson A.W.,Frants R.R.
Cloning and sequencing of rhesus monkey pepsinogen A cDNA.
Gene
65
179-185
1988
