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Sequence of CHIB1_ASPFM

EC Number:3.2.1.14

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
chitinase
Q873X9
Neosartorya fumigata
433
47622
Reaction
chitopentaose + H2O = chitobiose + chitotriose
Other sequences found for EC No. 3.2.1.14

General information:

Sequence
show sequence in fasta format
  0 MRFATSTIVK VALLLSSLCV DAAVMWNRDT SSTDLEARAS SGYRSVVYFV NWAIYGRNHN
 60 PQDLPVERLT HVLYAFANVR PETGEVYMTD SWADIEKHYP GDSWSDTGNN VYGCIKQLYL
120 LKKQNRNLKV LLSIGGWTYS PNFAPAASTD AGRKNFAKTA VKLLQDLGFD GLDIDWEYPE
180 NDQQANDFVL LLKEVRTALD SYSAANAGGQ HFLLTVASPA GPDKIKVLHL KDMDQQLDFW
240 NLMAYDYAGS FSSLSGHQAN VYNDTSNPLS TPFNTQTALD LYRAGGVPAN KIVLGMPLYG
300 RSFANTDGPG KPYNGVGQGS WENGVWDYKA LPQAGATEHV LPDIMASYSY DATNKFLISY
360 DNPQVANLKS GYIKSLGLGG AMWWDSSSDK TGSDSLITTV VNALGGTGVF EQSQNELDYP
420 VSQYDNLRNG MQT
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
16936
Jaques A.K.,Fukamizo T.,Hall D.,Barton R.C.,Escott G.M.,Parkinson T.,Hitchcock C.A.,Adams D.J.
Disruption of the gene encoding the ChiB1 chitinase of Aspergillus fumigatus and characterization of a recombinant gene product.
Microbiology
149
2931-2939
2003
16937
Hu H.,Wang G.,Yang H.,Zhou J.,Mo L.,Yang K.,Jin C.,Jin C.,Rao Z.
Crystallization and preliminary crystallographic analysis of a native chitinase from the fungal pathogen Aspergillus fumigatus YJ-407.
Acta Crystallogr. D
60
939-940
2004
16938
Taib M.,Pinney J.W.,Westhead D.R.,McDowall K.J.,Adams D.J.
Differential expression and extent of fungal/plant and fungal/bacterial chitinases of Aspergillus fumigatus.
Arch. Microbiol.
184
78-81
2005
16939
Lu Y.,Yang H.,Hu H.,Wang Y.,Rao Z.,Jin C.
Mutation of Trp137 to glutamate completely removes transglycosyl activity associated with the Aspergillus fumigatus AfChiB1.
Glycoconj. J.
26
525-534
2009
16941
Rao F.V.,Houston D.R.,Boot R.G.,Aerts J.M.,Hodkinson M.,Adams D.J.,Shiomi K.,Omura S.,van Aalten D.M.
Specificity and affinity of natural product cyclopentapeptide inhibitors against A. fumigatus, human, and bacterial chitinases.
Chem. Biol.
12
65-76
2005
16942
Rao F.V.,Andersen O.A.,Vora K.A.,Demartino J.A.,van Aalten D.M.
Methylxanthine drugs are chitinase inhibitors: investigation of inhibition and binding modes.
Chem. Biol.
12
973-980
2005
16943
Schuttelkopf A.W.,Andersen O.A.,Rao F.V.,Allwood M.,Lloyd C.,Eggleston I.M.,van Aalten D.M.
Screening-based discovery and structural dissection of a novel family 18 chitinase inhibitor.
J. Biol. Chem.
281
27278-27285
2006
16944
Andersen O.A.,Nathubhai A.,Dixon M.J.,Eggleston I.M.,van Aalten D.M.
Structure-based dissection of the natural product cyclopentapeptide chitinase inhibitor argifin.
Chem. Biol.
15
295-301
2008