Sequence of CHS7_CRYNH
EC Number:2.4.1.16
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
chitin synthase
J9VMX7
Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
931
104529
Reaction
UDP-N-acetyl-alpha-D-glucosamine + [(1->4)-N-acetyl-beta-D-glucosaminyl]n = UDP + [(1->4)-N-acetyl-beta-D-glucosaminyl]n+1
Other sequences found for EC No. 2.4.1.16
General information:
Sequence
0 MVRHDPFTNS VSEDSSFTPS VNPSTPYPQS GHYRPYYPPQ LTYCQGQQGY QYDHTGDVGY
60 GGRSRRHGSW ASVNNEDNEE LTPLTTGPAS SSTFLTTDPY LSGGPDLPLS SSSASISSAG
120 ADFLRRQTVP RRGATIKKIK LTNGNFIADY PVPGPVSSSV EAKWLNDKTS NEFWHMRYTA
180 ATCDPDDFTP ENGWKLKTTS YNRETELLVA ITSYNEDKIL YARTLHNVML NIRDICNTKA
240 SKFWRRSAEE GRPGWQKIVV ALVADGLDPM DKQVLDVLQT IGVFQDGILK KEVDGKKTAA
300 HIFEYTTQLS IDATPQLVQP HPGDPNNLVP VQIIFVLKQE NSKKINSHRW LFNALGRQLQ
360 PEICVLLDAG TKPGHKAIYH LWEAFYNNQN LGGACGEIHA MIKKGVKLLN PLVAAQNFEY
420 KMSNILDKPL ESSFGYVSVL PGAFSAYRYK AIQGRPLTQY FHGDATLAAR LGKKGIYGMG
480 IFTKNMFLAE DRILCFELVA KKGEKWVLQY VKPSKAETDV PEQAAELISQ RRRWLNGSFA
540 ASVYSVFHFF RLYRSGHGPI RMLFLHIQAI YNIFSLIFSW FALANLWLTF SIIIELLPES
600 ANINLFGTAD ITHWINLVFA WVYLAFLMLQ LVLALGNRPK AEKGLYILTL WVYAFLSFYL
660 IVCSIILSVV AFKGALRDGG SIGAKLGNLF NSTNGVLVAA IMSTIGIYLI ASFLYRDPWH
720 MFSSFPQYML LAPSFTNVLN IYAFCNLHDV SWGTKGSDRA ESLPAISSSK QKDGETAVVE
780 EQQRSQGELD ESFKQVVRRA VAPYKPEDAD EKPNLDDQNR TFRTRLVVVW LLTNAALAIS
840 IQTLNGLDTT KPLVEACLPN SYNPENGTVI VSTNGTCITQ ALEHDGDKLQ DKQQIYFQAI
900 LWTTFALSMV RFIGCVFYWA MRQMGRCWRR N
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
144801
Janbon G.,Ormerod K.L.,Paulet D.,Byrnes E.J. III,Yadav V.,Chatterjee G.,Mullapudi N.,Hon C.-C.,Billmyre R.B.,Brunel F.,Bahn Y.-S.,Chen W.,Chen Y.,Chow E.W.L.,Coppee J.-Y.,Floyd-Averette A.,Gaillardin C.,Gerik K.J.,Goldberg J.,Gonzalez-Hilarion S.,Gujja S.,Hamlin J.L.,Hsueh Y.-P.,Ianiri G.,Jones S.,Kodira C.D.,Kozubowski L.,Lam W.,Marra M.,Mesner L.D.,Mieczkowski P.A.,Moyrand F.,Nielsen K.,Proux C.,Rossignol T.,Schein J.E.,Sun S.,Wollschlaeger C.,Wood I.A.,Zeng Q.,Neuveglise C.,Newlon C.S.,Perfect J.R.,Lodge J.K.,Idnurm A.,Stajich J.E.,Kronstad J.W.,Sanyal K.,Heitman J.,Fraser J.A.,Cuomo C.A.,Dietrich F.S.
Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation.
PLoS Genet.
10
0-0
2014
144802
Banks I.R.,Specht C.A.,Donlin M.J.,Gerik K.J.,Levitz S.M.,Lodge J.K.
A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans.
Eukaryot. Cell
4
1902-1912
2005
144803
Park H.S.,Chow E.W.,Fu C.,Soderblom E.J.,Moseley M.A.,Heitman J.,Cardenas M.E.
Calcineurin Targets Involved in Stress Survival and Fungal Virulence.
PLoS Pathog.
12
0-0
2016
144804
Rodrigues J.,Ramos C.L.,Frases S.,Godinho R.M.D.C.,Fonseca F.L.,Rodrigues M.L.
Lack of chitin synthase genes impacts capsular architecture and cellular physiology in Cryptococcus neoformans.
Cell Surf.
2
14-23
2018
144805
Pianalto K.M.,Billmyre R.B.,Telzrow C.L.,Alspaugh J.A.
Roles for Stress Response and Cell Wall Biosynthesis Pathways in Caspofungin Tolerance in Cryptococcus neoformans.
Genetics
213
213-227
2019
