Sequence of GH101_STRR6
EC Number:3.2.1.97
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
endo-alpha-N-acetylgalactosaminidase
Q8DR60
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
1767
196144
Reaction
beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-[glycoprotein]-L-serine/L-threonine + H2O = beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine + [glycoprotein]-L-serine/L-threonine
Other sequences found for EC No. 3.2.1.97
General information:
Sequence
0 MNKGLFEKRC KYSIRKFSLG VASVMIGATF FGTSPVLADS VQSGSTANLP ADLATALATA
60 KENDGHDFEA PKVGEDQGSP EVTDGPKTEE ELLALEKEKP AEEKPKEDKP AAAKPETPKT
120 VTPEWQTVEK KEQQGTVTIR EEKGVRYNQL SSTAQNDNAG KPALFEKKGL TVDANGNATV
180 DLTFKDDSEK GKSRFGVFLK FKDTKNNVFV GYDKDGWFWE YKSPTTSTWY RGSRVAAPET
240 GSTNRLSITL KSDGQLNASN NDVNLFDTVT LPAAVNDHLK NEKKILLKAG SYDDERTVVS
300 VKTDNQEGVK TEDTPAEKET GPEVDDSKVT YDTIQSKVLK AVIDQAFPRV KEYSLNGHTL
360 PGQVQQFNQV FINNHRITPE VTYKKINETT AEYLMKLRDD AHLINAEMTV RLQVVDNQLH
420 FDVTKIVNHN QVTPGQKIDD ERKLLSSISF LGNALVSVSS DQTGAKFDGA TMSNNTHVSG
480 DDHIDVTNPM KDLAKGYMYG FVSTDKLAAG VWSNSQNSYG GGSNDWTRLT AYKETVGNAN
540 YVGIHSSEWQ WEKAYKGIVF PEYTKELPSA KVVITEDANA DKKVDWQDGA IAYRSIMNNP
600 QGWKKVKDIT AYRIAMNFGS QAQNPFLMTL DGIKKINLHT DGLGQGVLLK GYGSEGHDSG
660 HLNYADIGKR IGGVEDFKTL IEKAKKYGAH LGIHVNASET YPESKYFNEK ILRKNPDGSY
720 SYGWNWLDQG INIDAAYDLA HGRLARWEDL KKKLGDGLDF IYVDVWGNGQ SGDNGAWATH
780 VLAKEINKQG WRFAIEWGHG GEYDSTFHHW AADLTYGGYT NKGINSAITR FIRNHQKDAW
840 VGDYRSYGGA ANYPLLGGYS MKDFEGWQGR SDYNGYVTNL FAHDVMTKYF QHFTVSKWEN
900 GTPVTMTDNG STYKWTPEMR VELVDADNNK VVVTRKSNDV NSPQYRERTV TLNGRVIQDG
960 SAYLTPWNWD ANGKKLSTDK EKMYYFNTQA GATTWTLPSD WAKSKVYLYK LTDQGKTEEQ
1020 ELTVKDGKIT LDLLANQPYV LYRSKQTNPE MSWSEGMHIY DQGFNSGTLK HWTISGDASK
1080 AEIVKSQGAN DMLRIQGNKE KVSLTQKLTG LKPNTKYAVY VGVDNRSNAK ASITVNTGEK
1140 EVTTYTNKSL ALNYVKAYAH NTRRNNATVD DTSYFQNMYA FFTTGSDVSN VTLTLSREAG
1200 DEATYFDEIR TFENNSSMYG DKHDTGKGTF KQDFENVAQG IFPFVVGGVE GVEDNRTHLS
1260 EKHDPYTQRG WNGKKVDDVI EGNWSLKTNG LVSRRNLVYQ TIPQNFRFEA GKTYRVTFEY
1320 EAGSDNTYAF VVGKGEFQSG RRGTQASNLE MHELPNTWTD SKKAKKATFL VTGAETGDTW
1380 VGIYSTGNAS NTRGDSGGNA NFRGYNDFMM DNLQIEEITL TGKMLTENAL KNYLPTVAMT
1440 NYTKESMDAL KEAVFNLSQA DDDISVEEAR AEIAKIEALK NALVQKKTAL VADDFASLTA
1500 PAQAQEGLAN AFDGNLSSLW HTSWGGGDVG KPATMVLKEA TEITGLRYVP RGSGSNGNLR
1560 DVKLVVTDES GKEHTFTATD WPDNNKPKDI DFGKTIKAKK IVLTGTKTYG DGGDKYQSAA
1620 ELIFTRPQVA ETPLDLSGYE AALAKAQKLT DKDNQEEVAS VQASMKYATD NHLLTERMVE
1680 YFADYLNQLK DSATKPDAPT VEKPEFKLSS VASDQGKTPD YKQEIARPET PEQILPATGE
1740 SQFDTALFLA SVSLALSALF VVKTKKD
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1062683
Hoskins J.,Alborn W.E. Jr.,Arnold J.,Blaszczak L.C.,Burgett S.,DeHoff B.S.,Estrem S.T.,Fritz L.,Fu D.-J.,Fuller W.,Geringer C.,Gilmour R.,Glass J.S.,Khoja H.,Kraft A.R.,Lagace R.E.,LeBlanc D.J.,Lee L.N.,Lefkowitz E.J.,Lu J.,Matsushima P.,McAhren S.M.,McHenney M.,McLeaster K.,Mundy C.W.,Nicas T.I.,Norris F.H.,O'Gara M.,Peery R.B.,Robertson G.T.,Rockey P.,Sun P.-M.,Winkler M.E.,Yang Y.,Young-Bellido M.,Zhao G.,Zook C.A.,Baltz R.H.,Jaskunas S.R.,Rosteck P.R. Jr.,Skatrud P.L.,Glass J.I.
Genome of the bacterium Streptococcus pneumoniae strain R6.
J. Bacteriol.
183
5709-5717
2001
1062684
Umemoto J.,Bhavanandan V.P.,Davidson E.A.
Purification and properties of an endo-alpha-N-acetyl-D-galactosaminidase from Diplococcus pneumoniae.
J. Biol. Chem.
252
8609-8614
1977
1062685
Willis L.M.,Zhang R.,Reid A.,Withers S.G.,Wakarchuk W.W.
Mechanistic investigation of the endo-alpha-N-acetylgalactosaminidase from Streptococcus pneumoniae R6.
Biochemistry
48
10334-10341
2009
1062686
Caines M.E.,Zhu H.,Vuckovic M.,Willis L.M.,Withers S.G.,Wakarchuk W.W.,Strynadka N.C.
The structural basis for T-antigen hydrolysis by Streptococcus pneumoniae: a target for structure-based vaccine design.
J. Biol. Chem.
283
31279-31283
2008
