Sequence of PEPA_SUNMU
EC Number:3.4.23.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Preferential cleavage: hydrophobic, preferably aromatic, residues in P1 and P1' positions. Cleaves Phe1-/-Val, Gln4-/-His, Glu13-/-Ala, Ala14-/-Leu, Leu15-/-Tyr, Tyr16-/-Leu, Gly23-/-Phe, Phe24-/-Phe and Phe25-/-Tyr bonds in the B chain of insulin
Other sequences found for EC No. 3.4.23.1
General information:
Sequence
0 MKKLLLLLGL VALSECLYKV PLVKKKSLRQ NLIENGLLKD FLAKHNVNPA SKYFPTEAAT
60 ELADQPLVNY MDMEYFGTIG IGTPPQEFTV IFDTGSSNLW VPSVYCSSPA CSNHNRFNPQ
120 KSSTFQSTSQ TLSIAYGTGS MTGVLGYDTV QVAGIADTNQ IFGLSQTEPG SFLYYSPFDG
180 ILGLAYPNIA SSGATPVFDN MWNQGLVSQD LFSVYLSSND QSGSVVIFGG IDSSYYTGNL
240 NWVPLSSEGY WQITVDSITM NGQAIACSGS CQAIVDTGTS LLSGPNNAIA NIQKSIGASQ
300 NANGQMVVSC SSIQSLPDIV FTINGIQYPL PASAYILQNQ QDCTSGFQGM DIPTPSGELW
360 ILGDVFIRQY FAVFDRGNNR VGLAPVA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
73410
Narita Y.,Oda S.,Takenaka O.,Kageyama T.
Phylogenetic position of Eulipotyphla inferred from the cDNA sequences of pepsinogens A and C.
Mol. Phylogenet. Evol.
21
32-42
2001
73411
Narita Y.,Oda S.,Moriyama A.,Takenaka O.,Kageyama T.
Pepsinogens and pepsins from house musk shrew, Suncus murinus: purification, characterization, determination of the amino-acid sequences of the activation segments, and analysis of proteolytic specificities.
J. Biochem.
121
1010-1017
1997
