Sequence of OTC_MYCTU
EC Number:2.1.3.3
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
ornithine carbamoyltransferase
P9WIT9
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
307
33057
Reaction
carbamoyl phosphate + L-ornithine = phosphate + L-citrulline
Other sequences found for EC No. 2.1.3.3
General information:
Sequence
0 MIRHFLRDDD LSPAEQAEVL ELAAELKKDP VSRRPLQGPR GVAVIFDKNS TRTRFSFELG
60 IAQLGGHAVV VDSGSTQLGR DETLQDTAKV LSRYVDAIVW RTFGQERLDA MASVATVPVI
120 NALSDEFHPC QVLADLQTIA ERKGALRGLR LSYFGDGANN MAHSLLLGGV TAGIHVTVAA
180 PEGFLPDPSV RAAAERRAQD TGASVTVTAD AHAAAAGADV LVTDTWTSMG QENDGLDRVK
240 PFRPFQLNSR LLALADSDAI VLHCLPAHRG DEITDAVMDG PASAVWDEAE NRLHAQKALL
300 VWLLERS
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
454693
Cole S.T.,Brosch R.,Parkhill J.,Garnier T.,Churcher C.M.,Harris D.E.,Gordon S.V.,Eiglmeier K.,Gas S.,Barry C.E. III,Tekaia F.,Badcock K.,Basham D.,Brown D.,Chillingworth T.,Connor R.,Davies R.M.,Devlin K.,Feltwell T.,Gentles S.,Hamlin N.,Holroyd S.,Hornsby T.,Jagels K.,Krogh A.,McLean J.,Moule S.,Murphy L.D.,Oliver S.,Osborne J.,Quail M.A.,Rajandream M.A.,Rogers J.,Rutter S.,Seeger K.,Skelton S.,Squares S.,Squares R.,Sulston J.E.,Taylor K.,Whitehead S.,Barrell B.G.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature
393
537-544
1998
454694
Moradian F.,Garen C.,Cherney L.,Cherney M.,James M.N.
Expression, purification, crystallization and preliminary X-ray analysis of two arginine-biosynthetic enzymes from Mycobacterium tuberculosis.
Acta Crystallogr. F
62
986-988
2006
454695
Kelkar D.S.,Kumar D.,Kumar P.,Balakrishnan L.,Muthusamy B.,Yadav A.K.,Shrivastava P.,Marimuthu A.,Anand S.,Sundaram H.,Kingsbury R.,Harsha H.C.,Nair B.,Prasad T.S.,Chauhan D.S.,Katoch K.,Katoch V.M.,Kumar P.,Chaerkady R.,Ramachandran S.,Dash D.,Pandey A.
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol. Cell. Proteomics
10
0-0
2011
454696
Sankaranarayanan R.,Cherney M.M.,Cherney L.T.,Garen C.R.,Moradian F.,James M.N.
The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism.
J. Mol. Biol.
375
1052-1063
2008
