Sequence of TY3H_MOUSE
EC Number:1.14.16.2
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
L-tyrosine + a 5,6,7,8-tetrahydropteridine + O2 = L-dopa + a 4a-hydroxy-5,6,7,8-tetrahydropteridine
Other sequences found for EC No. 1.14.16.2
General information:
Sequence
0 MPTPSASSPQ PKGFRRAVSE QDTKQAEAVT SPRFIGRRQS LIEDARKERE AAAAAAAAAV
60 ASAEPGNPLE AVVFEERDGN AVLNLLFSLR GTKPSSLSRA LKVFETFEAK IHHLETRPAQ
120 RPLAGSPHLE YFVRFEVPSG DLAALLSSVR RVSDDVRSAR EDKVPWFPRK VSELDKCHHL
180 VTKFDPDLDL DHPGFSDQAY RQRRKLIAEI AFQYKQGEPI PHVEYTKEEI ATWKEVYATL
240 KGLYATHACR EHLEAFQLLE RYCGYREDSI PQLEDVSHFL KERTGFQLRP VAGLLSARDF
300 LASLAFRVFQ CTQYIRHASS PMHSPEPDCC HELLGHVPML ADRTFAQFSQ DIGLASLGAS
360 DEEIEKLSTV YWFTVEFGLC KQNGELKAYG AGLLSSYGEL LHSLSEEPEV RAFDPDTAAV
420 QPYQDQTYQP VYFVSESFSD AKDKLRNYAS RIQRPFSVKF DPYTLAIDVL DSPHTIRRSL
480 EGVQDELHTL TQALSAIS
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1268993
Ichikawa S.,Sasaoka T.,Nagatsu T.
Primary structure of mouse tyrosine hydroxylase deduced from its cDNA.
Biochem. Biophys. Res. Commun.
176
1610-1616
1991
1268996
Zhou Q.Y.,Quaife C.J.,Palmiter R.D.
Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development.
Nature
374
640-643
1995
1268997
Ihara M.,Yamasaki N.,Hagiwara A.,Tanigaki A.,Kitano A.,Hikawa R.,Tomimoto H.,Noda M.,Takanashi M.,Mori H.,Hattori N.,Miyakawa T.,Kinoshita M.
Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity.
Neuron
53
519-533
2007
1268998
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
1268999
Nguyen M.T.,Vemaraju S.,Nayak G.,Odaka Y.,Buhr E.D.,Alonzo N.,Tran U.,Batie M.,Upton B.A.,Darvas M.,Kozmik Z.,Rao S.,Hegde R.S.,Iuvone P.M.,Van Gelder R.N.,Lang R.A.
An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye.
Nat. Cell Biol.
21
420-429
2019
