Sequence of CYB2_YEAST
EC Number:1.1.2.3
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
L-lactate dehydrogenase (cytochrome)
P00175
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
591
65539
Reaction
(S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c + 2 H+
Other sequences found for EC No. 1.1.2.3
General information:
Sequence
0 MLKYKPLLKI SKNCEAAILR ASKTRLNTIR AYGSTVPKSK SFEQDSRKRT QSWTALRVGA
60 ILAATSSVAY LNWHNGQIDN EPKLDMNKQK ISPAEVAKHN KPDDCWVVIN GYVYDLTRFL
120 PNHPGGQDVI KFNAGKDVTA IFEPLHAPNV IDKYIAPEKK LGPLQGSMPP ELVCPPYAPG
180 ETKEDIARKE QLKSLLPPLD NIINLYDFEY LASQTLTKQA WAYYSSGAND EVTHRENHNA
240 YHRIFFKPKI LVDVRKVDIS TDMLGSHVDV PFYVSATALC KLGNPLEGEK DVARGCGQGV
300 TKVPQMISTL ASCSPEEIIE AAPSDKQIQW YQLYVNSDRK ITDDLVKNVE KLGVKALFVT
360 VDAPSLGQRE KDMKLKFSNT KAGPKAMKKT NVEESQGASR ALSKFIDPSL TWKDIEELKK
420 KTKLPIVIKG VQRTEDVIKA AEIGVSGVVL SNHGGRQLDF SRAPIEVLAE TMPILEQRNL
480 KDKLEVFVDG GVRRGTDVLK ALCLGAKGVG LGRPFLYANS CYGRNGVEKA IEILRDEIEM
540 SMRLLGVTSI AELKPDLLDL STLKARTVGV PNDVLYNEVY EGPTLTEFED A
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
22604
Guiard B.
Structure, expression and regulation of a nuclear gene encoding a mitochondrial protein: the yeast L(+)-lactate cytochrome c oxidoreductase (cytochrome b2).
EMBO J.
4
3265-3272
1985
22605
Bowman S.,Churcher C.M.,Badcock K.,Brown D.,Chillingworth T.,Connor R.,Dedman K.,Devlin K.,Gentles S.,Hamlin N.,Hunt S.,Jagels K.,Lye G.,Moule S.,Odell C.,Pearson D.,Rajandream M.A.,Rice P.,Skelton J.,Walsh S.V.,Whitehead S.,Barrell B.G.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
Nature
387
90-93
1997
22606
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
22607
Ghrir R.,Becam A.-M.,Lederer F.
Primary structure of flavocytochrome b2 from baker's yeast. Purification by reverse-phase high-pressure liquid chromatography and sequencing of fragment alpha cyanogen bromide peptides.
Eur. J. Biochem.
139
59-74
1984
22608
Lederer F.,Cortial S.,Becam A.-M.,Haumont P.-Y.,Perez L.
Complete amino acid sequence of flavocytochrome b2 from baker's yeast.
Eur. J. Biochem.
152
419-428
1985
22609
Guiard B.,Lederer F.,Jacq C.
More similarity between bakers'yeast L-(+)-lactate dehydrogenase and liver microsomal sytochrome B5.
Nature
255
422-423
1975
22610
Grandier-Vazeille X.,Bathany K.,Chaignepain S.,Camougrand N.,Manon S.,Schmitter J.-M.
Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.
Biochemistry
40
9758-9769
2001
22611
Guiard B.,Lederer F.
Complete amino acid sequence of the heme-binding core in bakers' yeast cytochrome b2 (L-(+)-lactate dehydrogenase).
Biochimie
58
305-316
1976
22612
Jacq C.,Lederer F.
Cytochrome b2 from bakers' yeast (L-lactate dehydrogenase). A double-headed enzyme.
Eur. J. Biochem.
41
311-320
1974
22613
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
22614
Voegtle F.N.,Burkhart J.M.,Rao S.,Gerbeth C.,Hinrichs J.,Martinou J.C.,Chacinska A.,Sickmann A.,Zahedi R.P.,Meisinger C.
Intermembrane space proteome of yeast mitochondria.
Mol. Cell. Proteomics
11
1840-1852
2012
22615
Xia Z.-X.,Mathews F.S.
Molecular structure of flavocytochrome b2 at 2.4-A resolution.
J. Mol. Biol.
212
837-863
1990
22616
Cunane L.M.,Barton J.D.,Chen Z.-W.,Welsh F.E.,Chapman S.K.,Reid G.A.,Mathews F.S.
Crystallographic study of the recombinant flavin-binding domain of Baker's yeast flavocytochrome b(2): comparison with the intact wild-type enzyme.
Biochemistry
41
4264-4272
2002
22617
Tsai C.L.,Gokulan K.,Sobrado P.,Sacchettini J.C.,Fitzpatrick P.F.
Mechanistic and structural studies of H373Q flavocytochrome b2: effects of mutating the active site base.
Biochemistry
46
7844-7851
2007
