EC Number   |
Protein Variants |
Reference |
|---|
    6.1.1.4 | A156V |
mutation in beta-subunit, the ratio of turnover-number to Km-value is identical to the wild-type ratio |
662970 |
| 6.1.1.4 | A293D |
81% decreased activity, highly decreased editing function, very strong binding of ATP, high decrease in Km for the substrates, more sensitive too inhibition by ATP, increased heat lability compared to the wild-type |
650024 |
| 6.1.1.4 | A293D |
site-directed mutagenesis, the mutant activity is similar to the wild-type enzyme |
672264 |
| 6.1.1.4 | A293E |
site-directed mutagenesis, the mutant activity is similar to the wild-type enzyme |
672264 |
| 6.1.1.4 | A293F |
54% decreased activity compared to the wild-type, more sensitive too inhibition by ATP |
650024 |
| 6.1.1.4 | A293G |
50% decreased activity, decreased editing function, stronger binding of ATP, decrease in Km for the substrates, more sensitive too inhibition by ATP |
650024 |
| 6.1.1.4 | A293I |
51% decreased activity, decreased editing function, stronger binding of ATP, decrease in Km for the substrates, more sensitive too inhibition by ATP |
650024 |
| 6.1.1.4 | A293K |
site-directed mutagenesis, the post-transfer editing activity of the isolated CP1-domain is enhanced compared to the wild-type enzyme's domain |
672264 |
| 6.1.1.4 | A293R |
30% decreased activity, decreased editing function, stronger binding of ATP, decrease in Km for the substrates |
650024 |
| 6.1.1.4 | A293R |
site-directed mutagenesis, the post-transfer editing activity of the isolated CP1-domain is enhanced compared to the wild-type enzyme's domain |
672264 |
