EC Number   |
Protein Variants |
Reference |
|---|
   3.4.24.B20 | A359V |
homolog of the human pathogenic A510V mutation of paraplegin (SPG7), does not affect the dynamic behavior of the protease but impairs the ATP-coupled domain compaction |
-, 754430 |
| 3.4.24.B20 | D326N |
the mutant does not cleave delta32 protein |
720678 |
| 3.4.24.B20 | G195D |
the mutant does not cleave delta32 protein |
720678 |
| 3.4.24.B20 | G267D |
the mutant does not cleave delta32 protein |
720678 |
| 3.4.24.B20 | G302S |
the mutant does not cleave delta32 protein |
720678 |
| 3.4.24.B20 | G404L |
site-directed mutagenesis, the mutant is monomeric and inactive in the ATPase assay and possesses only very low proteolytic activity |
713403 |
| 3.4.24.B20 | G433R |
the mutant does not cleave delta32 protein |
720678 |
| 3.4.24.B20 | H416Y |
mutation in isoform Ftsh1, inactive |
-, 753669 |
| 3.4.24.B20 | H417L |
the mutant accumulates about 20% relative to the wild type enzyme and does not cleave delta32 protein |
720678 |
| 3.4.24.B20 | H420Y |
mutation in isoform Ftsh2, inactive |
-, 753669 |
