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Literature summary for 3.4.24.B20 extracted from

  • Zhang, D.; Kato, Y.; Zhang, L.; Fujimoto, M.; Tsutsumi, N.; Sodmergen, N.; Sakamoto, W.
    The FtsH protease heterocomplex in Arabidopsis: dispensability of type-B protease activity for proper chloroplast development (2010), Plant Cell, 22, 3710-3725.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.B20

Cloned(Commentary)

Cloned (Comment) Organism
mutant enzymes are expressed in Escherichia coli AR5088 cells Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
D326N the mutant does not cleave delta32 protein Arabidopsis thaliana
G195D the mutant does not cleave delta32 protein Arabidopsis thaliana
G267D the mutant does not cleave delta32 protein Arabidopsis thaliana
G302S the mutant does not cleave delta32 protein Arabidopsis thaliana
G433R the mutant does not cleave delta32 protein Arabidopsis thaliana
H417L the mutant accumulates about 20% relative to the wild type enzyme and does not cleave delta32 protein Arabidopsis thaliana
H488L the FtsH2 mutation inhibits zinc binding and inactivates proteolysis Arabidopsis thaliana
P320L the mutant does not cleave delta32 protein Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
-
 Arabidopsis thaliana 9507
-
thylakoid membrane
-
 Arabidopsis thaliana 42651
-

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ dependent on Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
delta32 protein + H2O Arabidopsis thaliana
-
 ?
-
 ?
photodamaged D1 protein + H2O Arabidopsis thaliana
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
 ecotype Col
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
delta32 protein + H2O
-
 Arabidopsis thaliana ?
-
 ?
photodamaged D1 protein + H2O
-
 Arabidopsis thaliana ?
-
 ?

Subunits

Subunits Comment Organism
heterohexamer
-
 Arabidopsis thaliana

Synonyms

Synonyms Comment Organism
FtsH2 isoform Arabidopsis thaliana
FtsH5 isoform Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
ATP dependent on Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction mutants lacking isoforms FtsH2 and FtsH5 are characterized by a typical leaf-variegated phenotype Arabidopsis thaliana