EC Number   |
Protein Variants |
Reference |
|---|
   3.4.23.B6 | A114R |
site-directed mutagenesis, the mutation alters the substrate specificity and reduces the enzyme activity and viral infectivity of COS-1 cells |
669413 |
| 3.4.23.B6 | C7A/C106A |
the midpoint of the urea unfolding curve for 12000 Da truncated enzyme is at 1.9 M urea, the denaturation curve for the C7A/C106A mutant is no longer sigmoidal in character, confirming that this mutant is very unstable |
693612 |
| 3.4.23.B6 | C7A/D26N/C106A |
triple mutant of the 12000 Da truncated enzyme form shows significantly decreased capacity to dimerize |
693612 |
| 3.4.23.B6 | D26N/C7A/C106A |
mutant of isozyme p12 showing altered structure and low target functions |
668797 |
| 3.4.23.B6 | H21A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
670079 |
| 3.4.23.B6 | more |
mutation of the cytoplasmic tail amino acids of the transmembrane protein TM, analysis of effects on the fusion to glycoprotein Env involving he protease activity, overview |
670080 |
| 3.4.23.B6 | N109I/Q115I |
site-directed mutagenesis, the mutation alters the substrate specificity and reduces the enzyme activity and viral infectivity of COS-1 cells |
669413 |
| 3.4.23.B6 | Q115I |
site-directed mutagenesis, the mutation alters the substrate specificity and reduces the enzyme activity and viral infectivity of COS-1 cells |
669413 |
| 3.4.23.B6 | Q9A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme, and mutant virions show reduced incorporation of the viral glycoprotein Env during virus assembly |
670079 |
| 3.4.23.B6 | Q9A/V20A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme, and mutant virions show reduced incorporation of the viral glycoprotein Env during virus assembly |
670079 |
