EC Number   |
Protein Variants |
Reference |
|---|
    3.1.8.1 | 185X |
construction of diverse mutants with polymorphism at residue 185 showing altered activities with substrate methyl parathion and paraoxon, overview |
666809 |
| 3.1.8.1 | A14T/A80V/K185R |
naturally occurring OPH genetic variant B1368, the variant shows altered kinetics with chlorpyrifos compared to the wild-type enzyme |
-, 663698 |
| 3.1.8.1 | A14T/A80V/K185R/H254R/I274N |
naturally occurring OPH genetic variant B2136, the variant shows altered kinetics with chlorpyrifos compared to the wild-type enzyme |
663698 |
| 3.1.8.1 | A14T/A80V/K185R/H257Y/I274N |
naturally occurring OPH genetic variant 22A11, the variant shows altered kinetics with chlorpyrifos compared to the wild-type enzyme |
-, 663698 |
| 3.1.8.1 | A14T/A80V/K185R/H257Y/I274N |
OPH genetic variant 22A11, constructed by site directed mutagenesis, the variant shows altered kinetics compared to the wild-type enzyme |
666809 |
| 3.1.8.1 | A14T/A80V/K185R/H257Y/I274N |
random saturation mutagenesis, variant 2H2, increased activity and altered kinetics compared to the wild-type enzyme |
666809 |
| 3.1.8.1 | A14T/A80V/K185R/I274N |
naturally occurring OPH genetic variant A1030, the variant shows altered kinetics with chlorpyrifos compared to the wild-type enzyme |
-, 663698 |
| 3.1.8.1 | A14T/L17P/A80V/V116I/K185R/A203T/I274N/P342S |
naturally occurring OPH genetic variant B3561, the variant shows altered kinetics with chlorpyrifos compared to the wild-type enzyme |
663698 |
| 3.1.8.1 | A14T/R67H/A80V/L87S/Q148R/K185R |
naturally occurring OPH genetic variant A1467, the variant shows altered kinetics with chlorpyrifos compared to the wild-type enzyme |
-, 663698 |
| 3.1.8.1 | A204C/T234C |
site-directed mutagenesis, Ala204 and Thr234 are located on the alpha-helices and gamma turn, respectively, thermostability of the mutant enzyme is increased compared to the wild-type, due to increased rigidity |
751134 |
