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Results 1 - 7 of 7
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EC Number Protein Variants Commentary Reference
Display the reaction diagram Show all sequences 2.8.1.B3C108/202/207/344A the mutant enzyme is 2900fold less active than the wild-type enzyme 691755
Display the reaction diagram Show all sequences 2.8.1.B3C108A mutation has no significant effect on ThiI activity 692956
Display the reaction diagram Show all sequences 2.8.1.B3C108A/C202A/C207A the mutant is fully active 739607
Display the reaction diagram Show all sequences 2.8.1.B3C202A mutation has no significant effect on ThiI activity 692956
Display the reaction diagram Show all sequences 2.8.1.B3C344A mutation results in the loss of function in vivo and a 2700fold reduction in activity measured in vitro 692956
Display the reaction diagram Show all sequences 2.8.1.B3C456A mutation impairs this sulfurtransferase activity. ThiI is incapable of supporting generation of 4-thiouridine in tRNA both in vitro and in vivo 691754
Display the reaction diagram Show all sequences 2.8.1.B3C456S the mutant is not able to restore growth of a thiI mutant strain in minimal medium suggesting that C456 is required for thiazole synthesis in vivo 725262
Results 1 - 7 of 7
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