EC Number   |
Protein Variants |
Reference |
|---|
    2.5.1.29 | A57L |
mutated enzyme produces mainly farnesyl diphosphate |
-, 638767 |
| 2.5.1.29 | A89F |
mutant enzyme yields shorter products than the wild-type enzyme. Substrate specificity is almost identical to that of farnesyl diphosphate synthase |
686706 |
| 2.5.1.29 | A89H |
mutant enzyme yields shorter products than the wild-type enzyme. Substrate specificity is almost identical to that of farnesyl diphosphate synthase |
686706 |
| 2.5.1.29 | A89L |
mutant enzyme yields shorter products than the wild-type enzyme |
686706 |
| 2.5.1.29 | D170E/M171P/I172A/S173M |
mutant enzyme shows considerably lower activity toward primer substrates with a short prenyl chain, DMAPP and GPP, than the wild-type enzyme |
638757 |
| 2.5.1.29 | D170E/M171P/I172A/S173M |
no activity with dimethylallyl diphosphate, low activity with geranyl diphosphate |
638757 |
| 2.5.1.29 | D170E/M171P/I172A/S173R |
low activity with dimethylallyl diphosphate, approx. 60% of wild-type activity with geranyl diphosphate |
638757 |
| 2.5.1.29 | D170E/M171P/I172R/S173V |
mutant enzyme shows considerably lower activity toward primer substrates with a short prenyl chain, DMAPP and GPP, than the wild-type enzyme. Scarcely accepts DMAPP as an allylic substrate. The mutant enzyme can not catalyze condensation of 3,7,ll-trimethyl-2,6,10,14-heptadecatetraenyl diphosphate with isopentenyl diphosphate. Does not accept short allylic substrates but forms products with the same length as those of the wild-type enzyme |
638757 |
| 2.5.1.29 | D170E/M171P/I172R/S173V |
no activity with dimethylallyl diphosphate, low activity with geranyl diphosphate |
638757 |
| 2.5.1.29 | DelP173/DelP174 |
decrease in reaction rate |
706332 |
